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Nov 20, 1987 - Assistant Professor, Dept of Oral and Maxillofacial Surgery, School of Dentistry, ... impacted third molar on patients referred to surgical Department of Tehran Azad ..... Miloro M. Petersons Principles of Oral and Maxillofacial Surgery. 2th ed. ... Tucker MR .Contemporary Oral and Maxillofacial Surgery. 4th ed.
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3 ‫ ﺷﻤﺎره‬/ 33 ‫ دوره‬/ 1388 ‫ ﺳﺎل‬/ ‫ﻣﺠﻠﻪ داﻧﺸﻜﺪه دﻧﺪاﻧﭙﺰﺷﻜﻲ ﻣﺸﻬﺪ‬

‫آزﻳﺘﺮوﻣﺎﻳﺴﻴﻦ ﺑﺮ ﭘﻴﺸﮕﻴﺮي از‬-‫آزﻳﺘﺮوﻣﺎﻳﺴﻴﻦ ﺑﺎ ﭘﻴﺮوﻛﺴﻲﻛﺎم‬-‫ﻣﻘﺎﻳﺴﻪ ﺗﺎﺛﻴﺮ ﺗﺮﻛﻴﺐ ﻧﭙﺮوﻛﺴﻦ‬ ‫ﻋﻮارض ﻧﺎﺷﻲ از ﺧﺎرج ﻛﺮدن دﻧﺪان ﻋﻘﻞ ﻧﻬﻔﺘﻪ‬ ****‫ دﻛﺘﺮ زﻫﺮا ﻧﺎﻃﻘﻲ‬،***‫ دﻛﺘﺮ رﺿﺎ زارع‬،**‫ دﻛﺘﺮ اﺳﺤﻖ ﻻﺳﻤﻲ‬،#*‫دﻛﺘﺮ اﻓﺸﻴﻦ ﺣﺮاﺟﻲ‬

‫ ﻓﻚ و ﺻﻮرت داﻧﺸﻜﺪه دﻧﺪاﻧﭙﺰﺷﻜﻲ داﻧﺸﮕﺎه آزاد اﺳﻼﻣﻲ واﺣﺪ ﺗﻬﺮان‬،‫* اﺳﺘﺎدﻳﺎر ﮔﺮوه ﺟﺮاﺣﻲ دﻫﺎن‬ ‫ ﻓﻚ و ﺻﻮرت داﻧﺸﻜﺪه دﻧﺪاﻧﭙﺰﺷﻜﻲ داﻧﺸﮕﺎه آزاد اﺳﻼﻣﻲ واﺣﺪ ﺗﻬﺮان‬،‫** داﻧﺸﻴﺎر ﮔﺮوه ﺟﺮاﺣﻲ دﻫﺎن‬ ‫ ﻓﻚ و ﺻﻮرت داﻧﺸﻜﺪه دﻧﺪاﻧﭙﺰﺷﻜﻲ و ﻣﺮﻛﺰ ﺗﺤﻘﻴﻘﺎت دﻧﺪاﻧﭙﺰﺷﻜﻲ داﻧﺸﮕﺎه ﻋﻠﻮم ﭘﺰﺷﻜﻲ ﻣﺸﻬﺪ‬،‫*** اﺳﺘﺎدﻳﺎر ﮔﺮوه آﺳﻴﺐ ﺷﻨﺎﺳﻲ دﻫﺎن‬ ‫**** دﻧﺪاﻧﭙﺰﺷﻚ‬ 88/2/26 : ‫ – ﺗﺎرﻳﺦ ﭘﺬﻳﺮش‬87/11/20 : ‫ﺗﺎرﻳﺦ اراﺋﻪ ﻣﻘﺎﻟﻪ‬

Comparison of Naproxen-Azithromycin Combination with Piroxicam-Azithromycin Combination in Prevention of Complications after Impacted Third Molar Extraction Afshin Haraji*#, Eshagh Lasemi**, Reza Zareh***, Zahra Nateghi**** * Assistant Professor, Dept of Oral and Maxillofacial Surgery, School of Dentistry, Tehran Islamic Azad University, Tehran, Iran. ** Associate Professor, Dept of Oral and Maxillofacial Surgery, School of Dentistry, Tehran Islamic Azad University, Tehran, Iran. *** Assistant Professor, Dept of Oral and Maxillofacial Surgery, School of Dentistry and Dental Research Center of Mashhad University of Medical Sciences, Mashhad, Iran. **** Dentist. Received: 9 February 2009; Accepted: 16 May 2009

Introduction: According to the large number of surgical removal of impacted third molar and prevalence of pain and side effects and importance of prevention to reduce these side effects and also presence of existing studies which show positive effects of prophylactic use of NSAIDs and antibiotics on healing after surgical removal of teeth and periodontal surgery, the present study was done to evaluate the effect of NSAIDs and antibiotics on pain and side effects after surgical removal of impacted third molar on patients referred to surgical Department of Tehran Azad university and two private surgical clinics in Tehran in 2008-2009. Materials & Methods: In this double-blind clinical trial study, approved by ethical committee of Azad University of Medical Sciences, 31 patients at the age of 17-27 who were candidate for bilateral impacted third molar extraction with the same difficulty index were recruited. Effects of naproxen-azithromycin combination (case side) and piroxicam-azithromycin combination (control side) were evaluated on pain, edema, dry socket, infection and trismus in different times. Data were analyzed with "Mann Whitney" and "Student t-tests". Results: From 60 evaluated samples, 24 were from maxilla and 36 were from mandible. Intensity of pain in study groups was lower in control group than the case group (P