VOLUME 48 / SUPPLEMENT 60 / SEPTEMBER 2016
Abstracts / 26th International Congress London, United Kingdom 4 – 7 September 2016
Online ISSN: 1399-3003
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ERS International Congress 2016 Your personal abstract book
Table Of Content 125. Epidemiological aspects of obstructive sleep apnoea
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PA340: Obstructive sleep apnea is a risk factor for osteoarthritis
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ERS International Congress 2016 Your personal abstract book
125. Epidemiological aspects of obstructive sleep apnoea PA340 Obstructive sleep apnea is a risk factor for osteoarthritis Asiye Kanbay¹, Oguz Kokturk², Aylin Pihtili¹, Erkan Ceylan¹, Selcan Tulu³, Ercan Madenci⁴, Handan Köseoglu⁵, Johan Verbraecken⁶ ¹Pulmonary Medicine, Istanbul Medeniyet University School of Medicine, Istanbul, Kadikoy, Turkey; ²Pulmonary Medicine, Gazi University School of Medicine, Ankara, Turkey; ³Internal Medicine, Istanbul Medeniyet University School of Medicine, Istanbul, Kadikoy, Turkey; ⁴Physical Theraphy and Rehabilitation, Istanbul Medeniyet University School of Medicine, Istanbul, Kadikoy, Turkey; ⁵Pulmonary Medicine, Gazi Osman Pasa University School of Medicine, Tokat, Turkey; ⁶Pulmonary Medicine, Antwerp University Hospital and University of Antwerp, Edegem, Belgium BACKGROUND AND AIM: Obstructive sleep apnea (OSA) syndrome is closely associated with cardiovascular and metabolic disorders. Recent studies showed that osteoarthritis (OA) is associated with cardiovascular disease as well as inflammation defined as "metabolic disorder". Due to the strong association of metabolic disorders with both OA and OSA, we aimed to evaluate the role of OSA in the development of OA and to investigate whether an association could be found between rising severity of OSA and OA. MATERIALS AND METHODS: Patients who got polysomnography due to suspicion of OSA were recruited in a cross-sectional study. Included patients were grouped according to apnea-hypopnea index (AHI) as mild (AHI between 5 and 14.9), moderately severe (AHI between 15 and 29,9), and severe OSA (AHI ≥- 30). Patients with AHI < 5 served as control group. KellgrenLawrence scoring system was used to express OA severity, which was graded as Grade 0, 1, 2, 3 and 4. RESULTS: 120 patients were enrolled into the study. Mean age was 52.4±11.5 years and 56% (68/120) of the patients were male. A strong correlation was present between severity of OSA and severity of OA. In Grade 4 OA group (33 patients), all patients had severe OSA and this association was independent from body-mass index. In Grade 1 OA group, none of the patients had severe OSA (p
