Adolescent Idiopathic Scoliosis - eJManager

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Apr 22, 2013 - cast immobilization with posterior spinal arthrodesis. [36]. In 1958, Risser described the progressive lateral to medial ossification of the iliac ...
Review Article

Archives of Clinical

Experimental Surgery

Increased of Langerhans Cells in Smokeless Tobacco-Associated Oral Mucosal Lesions Érica Dorigatti de Ávila1, Rafael Scaf de Molon2, Melaine de Almeida Lawall1, Renata Bianco Consolaro1, Alberto Consolaro1

Adolescent Idiopathic Scoliosis Safak Ekinci 1, Omer Ersen 2 1

2

Department of Orthopedics and Traumatology Ağrı Military Hospital Ağrı, Turkey Department of Orthopedics and Traumatology Erzurum Military Hospital Erzurum, Turkey

Received: March 28, 2013 Accepted: April 22, 2013 Arch Clin Exp Surg 2014;3:174-182 DOI:10.5455/aces.20130422110147 Corresponding author: Safak Ekinci, MD Department of Orthopedics and Traumatology Ağrı Military Hospital Ağrı, Turkey [email protected]

Abstract Abstract Objective: To evaluate the changes in the number of Langerhans Cells (LC) observed in the epithelium of

smokeless tobacco (SLT-induced) Scoliosis is called idiopathic when no lesions. other underlying disease can be identified. The etiology of adoMethods: Microscopic sections from biopsies carried in years the buccal mucosa of twenty patients, who were lescent idiopathic scoliosis (AIS) is still unknown despite out many of research effort. Theories on AIS’s etiology included tobacco mechanical, hormonal, metabolic, growth, andnon-SLT genetic users of SLT chronic users have of smokeless (SLT), were utilized. For neuromuscular, the control group, twenty abnormalities. Skeletally immature with adolescent idiopathic scoliosis are at risk curve with normal mucosa were selected.patients The sections were studied with routine coloring andofwere immunostained progression. The adolescent onset of severe idiopathic scoliosis has traditionally been evaluated usfor S-100, CD1a, Ki-67 and p63. These data were statistically analyzed by the Student’s t-test to investigate the ing standingin posteroanterior the full in spine to assess lateral with the leukoplakia Cobb differences the expressionradiographs of immuneofmarkers normal mucosa andcurvature in SLT-induced lesions. method. Scoliosis in children of school age and above primarily occurs in girls. The therapeutic goal in Results: There was a significant difference in the immunolabeling of all markers between normal mucosa children is to prevent progression. In children, scoliosis of 20° or more should be treated with a brace, and SLT-induced lesions (p