Great Western Hospital, Swindon, UK. Haitham Abdelmoteleb, Elisabeth Probst, John Iacovou. Pa erns of prostate cancer in men < 60 years of age. 32%. 21%.
PaFerns of prostate cancer in men < 60 years of age Haitham Abdelmoteleb, Elisabeth Probst, John Iacovou Great Western Hospital, Swindon, UK
RESULTS
Background • In the UK, the incidence rate of prostate cancer (PCa) in men aged 55-59 is 168 per 100,000 men. • Between 2010 and 2012, an average of 74% of PCa deaths was in men aged 75 years and over, and more than 99% were in those aged 55 years and over. • Age-specific mortality rates rise sharply from around age 55-59.
• 56 men met the inclusion criteria. • Mean age: 56 + 4 years. • Presentation: LUTS (33%), followed by rise in PSA (30.4%). • Mean PSA: 22.9 + 57.2 ng/ml • Risk Groups: Figure 1
• Five-year survival for prostate cancer in men aged < 60 years is 92%.
• Treatment Protocol: Figure 2
Treatment Protocol
METHODS
45.0%
40.0%
• Retrospective analysis of our database.
35.0%
• Period: January 2012 and December 2013.
AXIS TITLE
30.0%
25.0%
20.0%
• Inclusion criteria: - < 60 years of age at presentation of PCa.
15.0%
10.0%
5.0%
0.0%
• Exclusion criteria: - Previous diagnoses of Pca.
RALP
Treatment Protocol 41.0%
Radioth erapy 21.4%
Hormon al 7.1%
AS
HIFU
28.6%
1.8%
CONCLUSIONS Risk Groups
11%
32%
36%
• In our center, we found that PCa in younger men tend to have a more advanced presentation.
Low Risk
• Active surveillance as a management option should be considered with caution in this subgroup of men.