BMC Pediatrics
BioMed Central
Open Access
Case report
A neonatal presentation of factor V deficiency: A case report Amol Chingale1, Michael Eisenhut*1, Anjali Gadiraju1 and Ri Liesner2 Address: 1Department of Pediatrics, Luton and Dunstable Hospital NHS Foundation Trust, Luton, Bedfordshire, LU 4 0DZ, UK and 2Department of Hematology, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK Email: Amol Chingale -
[email protected]; Michael Eisenhut* -
[email protected]; Anjali Gadiraju -
[email protected]; Ri Liesner -
[email protected] * Corresponding author
Published: 21 February 2007 BMC Pediatrics 2007, 7:8
doi:10.1186/1471-2431-7-8
Received: 1 June 2006 Accepted: 21 February 2007
This article is available from: http://www.biomedcentral.com/1471-2431/7/8 © 2007 Chingale et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Factor V deficiency is a rare autosomal recessive coagulation disorder. Awareness of presenting features and management is important to avoid bleeding complications associated with mortality and neurodisability. Case presentation: A 6-day-old Pakistani boy was admitted with bleeding from the left nipple. His parents were first cousins. A coagulation screen showed a prothrombin time of 41 s (control 14 s), a partial thromboplastin time of 132 s (control 33 s) and a normal thrombin time of 15 s (control 14 s). Factor V activity was
