Journal of the College of Physicians and Surgeons Pakistan 2009, Vol. 19 (4): 232-235. INTRODUCTION. The prevalence of Diabetes Mellitus (DM) for all age.
ORIGINAL ARTICLE
Cardiac Autonomic Neuropathy (CAN) in Type-1 Diabetes Mellitus Patients and its Association with the Duration of Disease and Glycemic Control Haji Khan Khoharo1, Shuaib Ansari2, Imran Ali Shaikh3 and Fatima Qureshi4
ABSTRACT Objective: To determine the frequency of Cardiac Autonomic Neuropathy (CAN) in type-1 Diabetes mellitus patients and its association with the duration of disease and glycemic control. Study Design: Descriptive study. Place and Duration of Study: Department of Medicine, Liaquat University Hospital, Hyderabad/Jamshoro, from December, 2004 to April, 2005. Methodology: Fifty patients of type-1 Diabetes Mellitus (DM) of ≥10 years duration were selected. CAN was evaluated in terms of presence of resting tachycardia, loss of sinus arrhythmia and heart rate response to Valsalva maneuver by electrocardiogram (ECG). An R-R variation with respiration of >15 beats per minute was taken normal, while 10-15 beats and
