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European Heart Journal: Acute Cardiovascular Care http://acc.sagepub.com/
Acute Cardiovascular Care 2014 European Heart Journal: Acute Cardiovascular Care 2014 3: 1 DOI: 10.1177/2048872614549721 The online version of this article can be found at: http://acc.sagepub.com/content/3/2_suppl/1.citation
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EUROPEAN SOCIETY OF CARDIOLOGY ®
Acute Cardiovascular Care 2014
Rapid Fire Saturday, 18 October 2014 - 16:15 - 17:45 Myocardial and pericardial diseases 55 The prevalence and long-term outcomes of extreme right ventricular hypertrophy compared with that of extreme left ventricular hypertrophy in patients with hypertrophic cardiomyopathy X Y Guo,1 CM Fan,1 YJ Yang,1 LR Yan1 and YS Li1 1Fuwai Hospital, National Center for Cardiovascular Diseases, CAMS&PUMC, Key Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, beijing, China, People’s Republic of
Background: Extreme left ventricular hypertrophy (LVH) has been associated with a poor prognosis and a risk factor of sudden cardiac death in hypertrophic cardiomyopathy(HCM). Severe right ventricular hypertrophy(RVH) is rare and whether it also be linked to a poor outcome is unknown. The aim of this study was to investigate the differences of the prevalence and long-term outcomes between patients with extreme RVH and extreme LVH in HCM.
Methods: A retrospective study of 30 patients with extreme RVH (maximum RV wall thickness >10 mm)and 143 patients with extreme LVH (maximum LV wall thickness ≥30 mm) identified in a consecutive cohort consisting of 2320 patients with HCM was performed. Any other diseases capable of producing such right or left hypertrophy were excluded. The prevalence and natural history of the2 groups were compared. Results: The prevalence of extreme RVH was 1.3% and extreme LVH was 6.7% in Chinese HCM patients. Patients with extreme RVH tended to be younger p=0.02 and more women involved (p=0.01. The 10 years probability of cardiovascular mortality was significantly greater in extreme RVH group(log-rank, P= 0.017). Nevertheless cardiovascular morbidity were similar (p=0.07), among which progressing to heart failure was much more common in extreme RVH p
