CG GC TG AC CA GT CG TG TG TA CG GC - PLOS

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Page 1. CG. GC. TG. AC. CA. GT. CG. TG. TG. TA. CG. GC. 5'. 5'. 5'. 5'. 5'. 5'. 5'. 5'. In vivo Evolution. In vitro Bisulfite Reaction. No Mutation. Mutation on.
In vivo Evolution

No Mutation

5’

CG GC

Mutation on

In vitro Bisulfite Reaction

5’

Reverse Strand

Unme

thyla

ted

5’

CG

5’

TG

5’

TG AC

5’

TG

5’

CA GT

5’

TA

Forward Strand

Mutation on

CG GC

ted

yla Meth

Fig. S5