teniposide induces the transcription of heat shock genes in. HeLa cells (32). However, despite the fact that vepeside has been thoroughly documented to induce ...
Ciprofloxacin Induces an Immunomodulatory Stress Response in Human T Lymphocytes KRISTIAN RIESBECK,* ARNE FORSGREN, AGNETHE HENRIKSSON, AND ANDERS BREDBERG Department of Medical Microbiology, Lund University, Malmo ¨ University Hospital, S-205 02 Malmo ¨, Sweden Received 9 February 1998/Returned for modification 13 May 1998/Accepted 3 June 1998
Exposure of cells to adverse environmental conditions invokes a genetically programmed series of events resulting in the induction of specific genes. The fluoroquinolone antibiotic ciprofloxacin has recently been reported to upregulate interleukin-2 (IL-2) gene induction. In the present investigation, the effect of ciprofloxacin at supratherapeutic concentrations on immediate-early (
