Clinical features and risk factors of pancreatic cancer ... - Pancreatology

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Joon Hyuk Choi, Myung-Hwan Kim, Dong Wan Seo, Sang Soo Lee,. Do Hyun Park, Sung Koo Lee. Gastroenterology, University of Ulsan College of Medicine, ...
Abstracts / Pancreatology 13 (2013) S1–S80

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Conclusions: Analysis of EUS-FNA specimens with combination of conventional cytological smear and cell block may give higher diagnostic yield than cytological smear alone. Additional cell block may increase sensitivity and negative predictive value in the analysis of EUS-FNA specimen without decreasing specificity. Keywords: EUS-FNA, Cell block, Cytological smear

[P-058]. Clinical features and risk factors of pancreatic cancer in chronic pancreatitis Joon Hyuk Choi, Myung-Hwan Kim, Dong Wan Seo, Sang Soo Lee, Do Hyun Park, Sung Koo Lee Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea Background/aim: The relative risk of pancreatic cancer in chronic pancreatitis was reported as 13.3 compared with the prevalence in normal population. However, little is known about specific clinical features that can be warning sign of pancreatic cancer in chronic pancreatitis. The aims of this study were to compare clinical features of pancreatic cancer between with and without chronic pancreatitis and to find specific features in chronic pancreatitis preceding pancreatic cancer. Methods: We performed a chart review of patients with pancreatic cancer with underlying chronic pancreatitis who visited our institute, tertiary-referral hospital from 1989 to 2011 retrospectively. General clinical features such as age at diagnosis of pancreatic cancer, smoking, alcohol consumption were collected. Then, specific features of pancreatic cancer in chronic pancreatitis such as changes of pain, tumor marker, radiologic findings were compared to those of chronic pancreatitis patients without pancreatic cancer selected by using propensity score matching. Results: Total 40 patients were enrolled. In propensity score matched pairs (1:3 match) using covariates including age, sex, smoking, alcohol consumption, and follow-up periods and intervals, there were differences in clinical presentations including jaundice (OR: 18.3, p