No associations were observed between SGA and exposure to combination ARV regimens. Conclusions. .... cal findings in 43% of cases, ultrasound dating in 20%, and both ultrasound and clinical findings in 29%. Preterm birth was defined as ...
MAJOR ARTICLE
Combination Antiretroviral Use and Preterm Birth D. Heather Watts,1 Paige L. Williams,2 Deborah Kacanek,2 Raymond Griner,2 Kenneth Rich,3 Rohan Hazra,1 Lynne M. Mofenson,1 and Hermann A. Mendez,4 for the Pediatric HIV/AIDS Cohort Study
Background. Use of antiretroviral drugs (ARVs) during pregnancy has been associated with higher risk of preterm birth. Methods. The Pediatric HIV/AIDS Cohort Study network’s Surveillance Monitoring for ART Toxicities study is a US-based cohort of human immunodeficiency virus (HIV)–exposed uninfected children. We evaluated maternal ARV use during pregnancy and the risk of any type of preterm birth (ie, birth before 37 completed weeks of gestation), the risk of spontaneous preterm birth (ie, preterm birth that occurred after preterm labor or membrane rupture, without other complications), and the risk of small for gestational age (SGA; ie, a birth weight of
