Correlation of Histology and Alpha-1-Fetoprotein Resurgence in Rat ...
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Correlation of Histology and Alpha-1-Fetoprotein Resurgence in Rat Liver Regeneration After Experimental Injury by Galactosamine W. D. KUHLMANN, K. WURSTER Laboratory of Experimental Medicine and Immunocytochemistry, Institut für Nuklearmedizin, DKFZ Heidelberg, Germany, and Institut für Pathologie, Heidelberg, Germany
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Summary Intraperitoneal injections of galactosamine-HCl in rats were followed by transitory elevations of serum alpha-fetoprotein (AFP) concentrations. These were associated with regeneration of the damaged liver; a maximum of serum AFP was reached on day 4 (2.08 ± 0.67 µg/ml). In sera of untreated rats, serum AFP levels were