Correlation of Histology and Alpha-1-Fetoprotein Resurgence in Rat ...

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cytoplasm of epithelial cells of bile ducts and canaliculi in portal spaces. ... AFP in sera, intensity of epithelial bile duct proliferation and cellular AFP staining.
Correlation of Histology and Alpha-1-Fetoprotein Resurgence in Rat Liver Regeneration After Experimental Injury by Galactosamine W. D. KUHLMANN, K. WURSTER Laboratory of Experimental Medicine and Immunocytochemistry, Institut für Nuklearmedizin, DKFZ Heidelberg, Germany, and Institut für Pathologie, Heidelberg, Germany

Virchows Arch. A Path. Anat. Histol. 387, 47-57, 1980

Summary Intraperitoneal injections of galactosamine-HCl in rats were followed by transitory elevations of serum alpha-fetoprotein (AFP) concentrations. These were associated with regeneration of the damaged liver; a maximum of serum AFP was reached on day 4 (2.08 ± 0.67 µg/ml). In sera of untreated rats, serum AFP levels were