CURRICULUM 2014/2015

UNIVERSITY OF SZEGED

Faculty of Medicine Faculty of Dentistry Faculty of Pharmacy

Where knowledge and challenge meet

CURRICULUM 2014/2015

2

Publisher: Prof. Dr. Gyula Szabó Program Director

Curriculum 2014/2015

3

Content Brief History of the University of Szeged Management of the University of Szeged Management of the Albert Szent-Györgyi Clinical Center Mangement of the Faculties Management of the Faculty of Medicine Management of the Faculty of Dentistry Management of the Faculty of Pharmacy Foreign Students' Secretariat Organizational units of the Faculties Faculty of Medicine Faculty of Dentistry Faculty of Pharmacy List of educational advisors and research consultants Faculty of Medicine Faculty of Dentistry Faculty of Pharmacy Academic Calendar Fees General Guidelines Expressions

4 5 6 7 8 9 10 11 13 19 20 21 24 24 25 26 27 29

Study Programs Faculty of Medicine General information regarding the credit system at the who have started their studies in 2013/2014 or later General information regarding the credit system at the who have started their studies befor 2013/2014 Suggested study plans Compulsory practices in summer Extracurricular Scientific Activity Recommended textbooks Syllabuses Basic and Pre-clinical Module Pre-clinical Module Clinical Module Faculty of Dentistry General information regarding the credit system at the Compulsory practices in summer Suggested study plans Recommended textbooks Syllabuses Basic Module Pre-clinical Module Clinical Module Faculty of Pharmacy General information regarding the credit system at the Suggested study plans Recommended textbooks Syllabuses 1st year 2nd year 3rd year 4th year 5th year

Faculty of Medicine for those 32 Faculty of Medicine for those 34 37 58 59 64 74 102 118 Faculty of Dentistry

153 157 158 178 182 195 210

Faculty of Pharmacy

Vow to be made by 1st year medical, dental and pharmacy students Oath to be taken by medical graduates Oath to be taken by pharmacy graduates

233 234 252 258 274 285 307 322 327 327 327

4 BRIEF HISTORY OF THE UNIVERSITY OF SZEGED Before the 12th century, intellectual and scholarly life concentrated in the monasteries. With the growing professionalisation of society in the 12th and 13th centuries, demand increased for educated professionals. The universities appeared in Europe from the 11th-12th century. Medieval universities were established for the study of arts, law, theology and medicine. Universities were not defined by location and space but by individuals banded together as a corporation. The end of the medieval period signalled the arrival of modern universities where teaching and research met. In 1581, following the establishment of universities in other regions of Central and Eastern Europe, István Báthory, the Prince of Transylvania, issued a founding document for a higher educational institute in Kolozsvár (Cluj-Napoca). The Jesuit Academy (Societatis Jesu Academia Claudiopolitana) was organized with two faculties, the Faculty of Philosophy and the Faculty of Theology. The academy was meant to have the rank of a university from the beginning; Prince Báthory endowed the institute with the right to confer baccalaureate and master’s degrees on its students. At that time, the university held a unique place in the intellectual activity of Hungary; it was the only institute for higher education in Hungary. The academy was soon closed due to religious and political turmoil, but the Jesuits re-established it and the institute gained more stability and prestige in the 17th century. From 1753, according to a decree passed by the Holy Roman Empress and Queen of Hungary and Bohemia, Maria Theresia, the institute functioned as a university, where teaching was carried out in German. She was one of the most significant proponents of enlightened absolutism; her educational reforms were highly lauded. 1774 saw not only the introduction of mandatory education but also the start of change for the University of Kolozsvár. After the Society of Jesus had been abolished, Maria Theresia entrusted the Piarists with the reorganization of the institute. As a result of the restructuring–in addition to the Faculties of Theology and Arts–two new faculties were established, the Faculty of Law (1774) and the Faculty of Medicine-Surgery (1775). Later on, these faculties served as the basis for the Hungarian Royal University of Kolozsvár, which was founded by King Francis Joseph I and the Hungarian Parliament in 1872. In 1881, the university was renamed after the king and bore his name until 1940. In 1919, the university had to leave its founding place and after a brief stay in Budapest, found new home in Szeged. From 1921 until 1940 the Ferenc József Tudományegyem (Francis Joseph University) gained more and more prestige. When in 1940 the university was divided and part of it moved back to Kolozsvár, the remaining staff and students, the laboratories and the library were reorganized. The university took the name of Miklós Horthy, who was a former Governor of Hungary. The first rector of this institute was Albert Szent-Györgyi, who received the most prestigious award of sciences in 1937, the Nobel-price, for his research conducted at the university. After World War II the institute assumed the name University of Szeged. In 1951 the Faculty of Medicine formed an independent institution under the name Medical University of Szeged. The pharmacy training was started as an independent faculty (separate from the medical faculty) in 1957, and the Division of Dentistry as part of the Faculty of Medicine in 1962. The English-Language Program for foreign students was established in 1985. From 1999 there is also a German-Language Program at the Faculty of Medicine. In 1987 the University assumed the name of its former Biochemistry Professor, Dean of the Faculty of Medicine, Rector, and Nobel Prize Laureate, Albert SzentGyörgyi who was first to isolate vitamin C, extracted from paprika. In 2000 the Albert Szent-Györgyi Medical University became again an integrated part of the University of Szeged. The Faculty of Medicine and the Faculty of Pharmacy functioned as the Albert Szent-Györgyi Medical and Pharmaceutical Center until July 2007. In the year 2004 the English-language dentistry program was launched and the Faculty of Dentistry was founded in January 2007.

The faculties obtain their basis for education by running a high-level clinical and research work. The task of the faculties is represented by three different fields: education, research-work, and prevention-treatment.

The University of Szeged is one of the most distinguished universities in Hungary and is proud to be considered as the intellectual successor of the University of Kolozsvár founded in 1581.


5 MANAGEMENT OF THE UNIVERSITY OF SZEGED Address: 6720 Szeged, Dugonics tér 13. Tel.: + 36 62 544-001

RECTOR Prof. GÁBOR SZABÓ Ph.D., D.Sc. Member of the Hungarian Academy of Sciences

VICE RECTOR FOR SCIENTIFIC AFFAIRS AND INNOVATION Prof. LAJOS KEMÉNY M.D., Ph.D., D.Sc. VICE RECTOR FOR EDUCATION Prof. KRISZTINA KARSAI LL.D., Ph. D. VICE RECTOR FOR INTERNATIONAL AFFAIRS AND PUBLIC RELATIONS Prof. TAMÁS MARTINEK D.Chem, Ph. D. GENERAL DIRECTOR FOR FINANCE AND MAINTENANCE Dr. ZOLTÁN MAJÓ Ph.D. GENERAL SECRETARY OF THE UNIVERSITY Dr. MÁTÉ DÖMÖTÖR LL.D. HEAD OF RECTOR’S CABINET GEORGINA PETRI

6 MANAGEMENT OF THE ALBERT SZENT-GYÖRGYI CLINICAL CENTER Office of the President Address: 6725 Szeged, Tisza Lajos krt. 107. Tel.: + 36 62 545-007, Fax: + 36 62 545-005 PRESIDENT Prof. ATTILA PÁL M.D., Ph.D. Tel.: + 36 62 545-007 VICE PRESIDENT FOR GENERAL AFFAIRS Prof. FERENC HAJNAL M.D., Ph.D. Tel.: + 36 62 545-007 VICE PRESIDENT FOR EQUIPMENT AFFAIRS Prof. GYÖRGY LÁZÁR M.D., Ph.D. Tel.: + 36 62 545-007 HEAD OF THE OFFICE OF THE PRESIDENT Dr. IVÁN KOVÁCS M.D., LL.D. Tel.: + 36 62 546-450 CHIEF COUNSELLOR MAGDOLNA BARÁTH-TÓTH Tel.: +36 62 545 007


7 MANAGEMENT OF THE FACULTIES FACULTY OF AGRICULTURE Dr. JÓZSEF HORVÁTH Ph.D. Dean FACULTY OF ARTS Prof. Dr. SZAJBÉLY MIHÁLY Ph.D. Dean FACULTY OF DENTISTRY Prof. KATALIN NAGY D.D.S., Ph.D. Dean FACULTY OF ECONOMICS AND BUSINESS ADMINISTRATION Dr. MÁRTON VILMÁNYI Dean FACULTY OF ENGINEERING Prof. GÁBOR KESZTHELYI-SZABÓ D.Sc. Rector Emeritus Dean FACULTY OF HEALTH SCIENCES AND SOCIAL STUDIES Dr. MÁRIA BARNAI Ph.D. Dean FACULTY OF LAW Prof. JÓZSEF HAJDÚ LL.D., Ph.D. Dean FACULTY OF MEDICINE Prof. FERENC BARI Ph.D., D.Sc. Dean FACULTY OF MUSIC Prof. PÉTER TÓTH D.L.A. Dean FACULTY OF PHARMACY Prof. habil. JUDIT HOHMANN D.Pharm., Ph.D., D.Sc. Dean FACULTY OF SCIENCE AND INFORMATICS Dr. LÁSZLÓ MUCSI Ph.D. Dean JUHÁSZ GYULA TEACHER TRAINING FACULTY Dr. ISTVÁN MARSI Ph.D. Dean

8 MANAGEMENT OF THE FACULTY OF MEDICINE Dean’s Office Address: 6720 Szeged, Tisza L. krt. 109. Tel.: + 36 62 545-016, Fax: + 36 62 545-478

DEAN Prof. FERENC BARI Ph.D., D.Sc.

VICE DEAN FOR GENERAL AND EDUCATIONAL AFFAIRS Prof. ANDRÁS PALKÓ M.D., Ph.D., D.Sc.

VICE DEAN FOR POSTGRADUATE EDUCATIONAL AFFAIRS Prof. FERENC HAJNAL M.D., Ph.D.

VICE DEAN FOR CLINICAL AFFAIRS Prof. ATTILA PÁL M.D., Ph.D.

VICE DEAN FOR SCIENTIFIC AND INTERNATIONAL AFFAIRS Prof. MÁRTA SZÉLL M.D., Ph.D, D.Sc.

VICE DEAN FOR FINANCIAL AFFAIRS Prof. GÁBOR TÓTH M.D., D.Sc.

DIRECTOR FOR POSTGRADUATE EDUCATIONAL AFFAIRS Prof. ANDREA FACSKÓ M.D., Ph.D.

DIRECTOR FOR EDUCATIONAL AFFAIRS Prof. GYULA SÁRY Ph.D., D.Sc.

HEAD OF THE DEAN'S OFFICE Dr. NÓRA FİZİ LL.D.


9 MANAGEMENT OF THE FACULTY OF DENTISTRY Dean’s Office Address: 6720 Szeged, Tisza Lajos körút 64. Tel.: + 36 62 545-299, Fax: + 36 62 545-282

DEAN Prof. KATALIN NAGY D.D.S., Ph.D. VICE DEAN Dr. KINGA TURZÓ Ph.D. DEAN'S ADVISORY Dr. ILDIKÓ PINKE Dr. PÉTER VÁLYI HEAD OF THE DEAN'S OFFICE ESZTER RÉVÉSZ KOCSIS

10 MANAGEMENT OF THE FACULTY OF PHARMACY Dean’s Office Address: 6720 Szeged, Zrínyi u. 9. Tel/Fax: + 36 62 545-022 DEAN Prof. habil. JUDIT HOHMANN D.Pharm., Ph.D., D.Sc. VICE DEAN FOR EDUCATIONAL AFFAIRS Dr. habil. LÁSZLÓ LÁZÁR D.Pharm., Ph.D. VICE DEAN FOR SCIENTIFIC AND FINANCIAL AFFAIRS Dr. habil. ISTVÁN ZUPKÓ D.Pharm., Ph.D. VICE DEAN FOR ADMISSIONS AND PUBLIC RELATIONS Dr. RÓBERT GÁSPÁR D.Pharm., Ph.D. HEAD OF THE DEAN'S OFFICE Dr. ILONA LANTOS D.Pharm.


11 FOREIGN STUDENTS' SECRETARIAT Address: 6720 Szeged, Dóm tér 12. Tel: + 36 62 545-458 Fax: +36 62 545-028, +36 62 544-562 Web: www.szegedmed.hu E-mail: [email protected]

Program Director: Prof. habil. GYULA SZABÓ M.D., Ph.D., D.Sc. Reception Hours: Monday, Thursday 12.00-13.00

Special advisor on housing affairs: Prof. habil. GÁBOR TÓTH Ph.D., D.Sc.

Head of the Foreign Students’ Secretariat: ANDREA LEHOCKI BALOG Tel.: + 36 62 545-458 E-mail: [email protected]

Academic officers: ALEXANDRA BÁNFI Tel.: +36 62 545-030 E-mail: [email protected] (English Medical Program: year 3)

SZILVIA BAUNOK Tel.: + 36 62 546-865 E-mail: [email protected]

(German Medical Program: application and admission, year 1, Student card: application) ÉVA CSÁSZÁR-KOVÁCS Tel.: + 36 62 545-031 E-mail: [email protected]

(English Pharmacy Program, English Medical Program: year 6) KATALIN FEHÉR Tel.: + 36 62 342-124 E-mail: [email protected]

(English Programs: application and admission Student card: application) DEZSİ JEREMIÁS Tel.: +36 62 545-029 E-mail: [email protected]

(English Dentistry Program)

12 ZSUZSANNA KOVÁCS Tel.: + 36 62 545-030 E-mail: [email protected]

(English Dentistry Program) ZSUZSANNA RAKONCZAI Tel.: +36 62 545-029 E-mail: [email protected]

(ETR -Unified Academic System- coordinator, English Medical Program: years 4-5) KATALIN SZIVERI Tel.: + 36 62 546-867 E-mail: [email protected]

(Tuition Fee, Health Insurance English programm – Student card: sticker) ERZSÉBET GUTÁNÉ NAGY Tel.: + 36 62 546-865 E-mail: [email protected]

(German Medical Program: application and admission, year 2, German programm – Student card: sticker) JUDIT TÓTH Tel.: + 36 62 545-836 E-mail: [email protected]

(English Medical Program: year 2) SZILVIA TÖRÖK-CSORDÁS Tel.: + 36 62 545-031 E-mail: [email protected]

(English Medical Program: year 1) ANITA TAKÁCS Tel.: + 36 62 546-867 E-mail: [email protected]

(Alumni, Graduates, English & German Foundation Years)

Reception hours:

Monday and Thursday:

9.30 - 12.00 and 14.30 - 15.30

Tuesday, Wednesday and Friday:

9.30 - 12.00


13 ORGANIZATIONAL UNITS OF THE FACULTIES

FACULTY OF MEDICINE Pre-Clinical Departments Department of Anatomy, Histology and Embryology (ANATÓMIAI, SZÖVET- ÉS FEJLİDÉSTANI INTÉZET) (Szeged, Kossuth Lajos sugárút 40. Tel: + 36 62 545-665, Fax: + 36 62 545-707) Head of Department: Prof. habil. ANDRÁS MIHÁLY, M.D., Ph.D., D.Sc. Department of Behavioural Sciences (MAGATARTÁSTUDOMÁNYI INTÉZET) (Szeged, Szentháromság u. 5. Tel./Fax: + 36 62 420-530, + 36 62 545-968) Head: Dr. habil. KATALIN BARABÁS, M.D., Ph.D. Section of Gerontology (GERONTOLÓGIAI OKTATÁSI RÉSZLEG) Head: Dr. habil. SÁNDOR BENKİ Ph.D. Department of Biochemistry (BIOKÉMIAI INTÉZET) (Szeged, Dóm tér 9. Tel.: + 36 62 545-096, Fax: + 36 62 545-097) Head of Department: Prof. habil. LÁSZLÓ DUX, M.D., Ph.D., D.Sc. English-Hungarian Medical Translator Training Group (formerly Department of Foreign Languages) (ANGOL-MAGYAR ORVOSI SZAKFORDÍTÓKÉPZİ CSOPORT) (Szeged, Szentháromság u. 5. Tel./Fax: + 36 62 425-521) Head of Department: Dr. ÉVA DEMETER, Ph.D. Department of Medical Biology (ORVOSI BIOLÓGIAI INTÉZET) (Szeged, Somogyi Béla u. 4. Tel.: + 36 62 545-109, Fax: + 36 62 545-131) Head of Department: Prof. ZSOLT BOLDOGKİI, Ph.D., D.Sc. Department of Medical Chemistry (ORVOSI VEGYTANI INTÉZET) (Szeged, Dóm tér 8. Tel.: + 36 62 545-136, Fax: + 36 62 545-971) Head of Department: Prof. habil. GÁBOR TÓTH, D.Chem., Ph.D., D.Sc. Supramolecular and Nanostructured Materials Research Group (MAGYAR TUDOMÁNYOS AKADÉMIA SZUPRAMOLEKULÁRIS ÉS NANOSZERKEZETŐ ANYAGOK KUTATÓCSOPORT (Szeged, Dóm tér 8. Tel.: + 36 62 544-593) Hungarian Academy of Sciences - University of Szeged Head: Prof. habil. IMRE DÉKÁNY D. Chem., Ph.D., D.Sc. Department of Medical Physics and Informatics (ORVOSI FIZIKAI ÉS ORVOSI INFORMATIKAI INTÉZET) (Szeged, Korányi fasor 9. Tel/Fax.: + 36 62 545-077) Head of Department: Prof. habil. FERENC BARI, Ph.D., D.Sc. Department of Medical Microbiology and Immunbiology (ORVOSI MIKROBIOLÓGIAI ÉS IMMUNBIOLÓGIAI INTÉZET) (Szeged, Dóm tér 10. Tel.: + 36 62 545-115, Fax: + 36 62 545-113) Head of Department: Dr. KATALIN BURIÁN, MD., Ph.D. Department of Pathophysiology (KÓRÉLETTANI INTÉZET) (Szeged, Semmelweis u. 1. Tel.: + 36 62 545-994, Fax: + 36 62 545-710) Head of Department: Prof. habil. GYULA SZABÓ, M.D., Ph.D., D.Sc. Department of Pharmacology and Pharmacotherapy (FARMAKOLÓGIAI ÉS FARMAKOTERÁPIAI INTÉZET) (Szeged, Dóm tér 12. Tel.: + 36 62 545-682, Fax: + 36 62 545-680) Head of Department: Prof. habil. ANDRÁS VARRÓ, M.D., Ph.D., D.Sc.

14 Cardiovascular Pharmacology Research Group (MTA-SZTE KERINGÉSFARMAKOLÓGIAI KUTATÓCSOPORT) (Szeged, Dóm tér 12. Tel.: + 36 62 545-681, Fax: + 36 62 544-565) Hungarian Academy of Sciences - University of Szeged Head: Prof. habil ANDRÁS VARRÓ, M.D., Ph.D., D.Sc. Department of Physiology (ÉLETTANI INTÉZET) (Szeged, Dóm tér 10. Tel.: + 36 62 545-101, Fax: + 36 62 545-842) Head of Department: Dr. habil. GYULA SÁRY, M.D., Ph.D. D.Sc. Department of Public Health (NÉPEGÉSZSÉGTANI INTÉZET) (Szeged, Dóm tér 10. Tel.: + 36 62 545-119, Fax: + 36 62 545-120) Head of Department: Dr. habil. EDIT PAULIK, M.D. Ph.D. Institute of Surgical Research (SEBÉSZETI MŐTÉTTANI INTÉZET) (Szeged, Szıkefalvi-Nagy B u. 6. Tel.: + 36 62 545-103, Fax: 545-743) Head of Department: Prof. habil. MIHÁLY BOROS, M.D., Ph.D., D.Sc. Department of Cell Biology and Molecular Medicine (SEJTBIOLÓGIA ÉS MOLEKULÁRIS MEDICINA TANSZÉK) (Szeged, Somogyi Béla u. 4. Tel./Fax: + 36 62 544-569) Head: Prof. habil. KÁROLY GULYA, Ph.D., D.Sc. Clinics, Clinical and Diagnostic Departments Department of Anesthesiology and Intensive Therapy (ANESZTEZIOLÓGIAI ÉS INTENZÍV TERÁPIÁS INTÉZET) (Szeged, Szıkefalvi-Nagy B u. 4. Tel.: + 36 62 545-168, Fax: + 36 62 545-593) Head of Department: Prof. habil. ZSOLT MOLNÁR, M.D., Ph.D., DEAA IV. Intensive Therapy Section (ANESZTEZIOLÓGIAI ÉS INTENZÍV TERÁPIÁS INTÉZET) (Szeged, Kossuth Lajos sgt. 42) Head of Section: Prof. GYÖRGY MAROSI, M.D. Department of Aviation and Space Medicine (REPÜLİ- ÉS ŐRORVOSI TANSZÉK) (Kecskemét, Balaton u. 17. Tel.: + 36 76-581-600/3170, Fax: +36 76 581-622 Head of Department: Prof. ANDOR GRÓSZ, M.D., Ph.D. Department of Laboratory Medicine (LABORATÓRIUMI MEDICINA INTÉZET) (Szeged, Semmelweis u. 6. Tel.: + 36 62 545-751, Fax: +36 62 544-559) Head of Department: Dr. habil. IMRE FÖLDESI, Pharm.D., Ph.D. Department of Clinical Microbiology (KLINIKAI MIKROBIOLÓGIAI DIAGNOSZTIKAI INTÉZET) Szeged, Semmelweis u. 6. Tel.: +36 62 545-398, Tel./Fax: +36 62 545-712 Head of Institute: Dr. habil. EDIT URBÁN, Pharm.D, Ph.D. Department of Dermatology and Allergology (BİRGYÓGYÁSZATI ÉS ALLERGOLÓGIAI KLINIKA) (Szeged, Korányi fasor 6. Tel.: + 36 62 545-277, Fax: +36 62 545-954) Head of Department: Prof. habil. LAJOS KEMÉNY, M.D., Ph.D., D.Sc.


15 Dermatology Research Group (MTA-SZTE DERMATOLÓGIAI KUTATÓCSOPORT) (Szeged, Korányi fasor 6. Tel.: + 36 62 545-277) Hungarian Academy of Sciences - University of Szeged Head: Prof. habil. LAJOS KEMÉNY, M.D., Ph.D., D.Sc.

Department of Family Medicine (CSALÁDORVOSI INTÉZET ÉS RENDELİ) (Szeged, Tisza Lajos krt 109. Tel./Fax: + 36 62 545-553) Head of Department: Prof. habil. FERENC HAJNAL, M.D., Ph.D. Department of Forensic Medicine (IGAZSÁGÜGYI ORVOSTANI INTÉZET) (Szeged, Kossuth Lajos sugárút 40. Tel./Fax: + 36 62 545-708) Appt. Head of Department: Dr. ÉVA KERESZTY, M.D., Ph.D. Departments of Internal Medicine First Department of Internal Medicine (I. SZ. BELGYÓGYÁSZATI KLINIKA) (Szeged, Korányi fasor 8-10, Secretary: Tel.: + 36 62 545-189, Fax: + 36 62 545-185) Head of Department: Dr. habil. GYÖRGY ÁBRAHÁM, M.D., Ph.D., II. Division of Internal Medicine (BELGYÓGYÁSZATI OSZTÁLY II.) (Szeged, Kálvária sgt. 57. Tel.: +36 62 561-361) Head of Division: Dr. JÓZSEF KISS, M.D. I. Division of Geriatry and Chronical Diseases (GERIÁTRIAI ÉS KRÓNIKUS BELGYÓGYÁSZATI OSZTÁLY I.) (Szeged, Kossuth L. sgt. 42. Tel.: +36 62 553-853) Head of Division: Dr. MAGDOLNA ZÖLLEI, M.D. Division of Infectology (INFEKTOLÓGIAI OSZTÁLY) (Szeged, Kálvária sgt. 57. Tel.: +36 62 561-361) Head of Division: Dr. EDIT HAJDÚ, M.D., Ph. D. Dyalisis Center (FMC MAGYARORSZÁGI EGÉSZSÉGÜGYI KFT. DIALÍZIS CENTRUM) (6724 Szeged, Korányi fasor 8-10., Tel.: 545-585) Head of Center: Dr. ZOLTÁN ONDRIK, M.D. Division of Endocrinology and Research Laboratory (ENDOKRINOLÓGIAI ÖNÁLLÓ OSZTÁLY ÉS KUTATÓ LABORATÓRIUM) (Szeged, Korányi fasor 8. Tel./Fax: + 36 62 545-211) Head of Division: Prof. habil. JÁNOS JULESZ, M.D., Ph.D. Second Department of Internal Medicine and Cardiological Center (II. SZ. BELGYÓGYÁSZATI KLINIKA ÉS KARDIOLÓGIAI KÖZPONT) (Szeged, Korányi fasor 6. Tel.: + 36 62 545-220, Fax: + 36 62 544-568) Head of Department: Prof. habil. TAMÁS FORSTER, M.D., Ph.D., D.Sc. Section of Invasive Cardiology (INVAZÍV KARDIOLÓGIAI RÉSZLEG) (Szeged, Szıkefalvi-Nagy B u. Fel: +36 62 544-915, 544-962, 545-473, Fax: +36 62 544- 915) Head of Section: Dr. IMRE UNGI, M.D. Divison of Cardiac Surgery (SZÍVSEBÉSZETI OSZTÁLY) (Szeged, Szıkefalvi-Nagy B u. Fel: +36 62 545-183, Fax: +36 62 544-563) Head of Division: Dr. GÁBOR BOGÁTS, M.D.

16

Department of Oral and Maxillofacial Surgery (ARC-, ÁLLCSONT- ÉS SZÁJSEBÉSZETI KLINIKA) (6725 Szeged, Kálvária sgt. 57. Tel.: + 36 62 561-393, Fax.: + 36 62 561-340) Head of Department: Prof. habil. JÓZSEF PIFFKÓ D.M.D., M.D., Ph.D. Department of Medical Genetics (ORVOSI GENETIKAI INTÉZET) (Szeged, Somogyi Béla u. 4. Tel.: + 36 62 545-134, Fax: + 36 62 545-699) Head of Department: Dr. habil. MÁRTA SZÉLL, M.D., Ph.D. Department of Neurology (NEUROLÓGIAI KLINIKA) (Szeged, Semmelweis u. 6. Tel.: + 36 62 545-351, Fax: + 36 62 545-597) Head of Department: Prof. habil. LÁSZLÓ VÉCSEI, M.D., Ph.D., D.Sc. Department of Neurosurgery (IDEGSEBÉSZETI KLINIKA) (Szeged, Semmelweis u. 6. Tel.: + 36 62 545-379, Fax: +36 62 545-972) Head of Department: Prof. habil. PÁL BARZÓ, M.D., Ph.D., D.Sc. Department of Nuclear Medicine (NUKLEÁRIS MEDICINA INTÉZET) (Szeged, Korányi fasor 8. Tel.: + 36 62 545-390, Fax: + 36 62 544-564) Head of Department: Prof. habil. LÁSZLÓ PÁVICS, M.D., Ph.D., D.Sc. Department of Obstetrics and Gynaecology (SZÜLÉSZETI ÉS NİGYÓGYÁSZATI KLINIKA) (Szeged, Semmelweis u. 1. Tel.: + 36 62 545-499, Fax: + 36 62 545-711) Head: Prof. habil. ATTILA PÁL, M.D., Ph.D. Department of Oncotherapy (ONKOTERÁPIÁS KLINIKA) (Section A: Szeged, Korányi fasor 12., Section B: Szeged, Semmelweis u. 1 Tel.: + 36 62 545-404, Fax: +36 62 545-922) Head of Department: Prof. habil. ZSUZSANNA KAHÁN, M.D., Ph.D. Department of Ophthalmology (SZEMÉSZETI KLINIKA) (Szeged, Korányi fasor 10-11. Tel.: + 36 62 545-487, Fax: + 36 62 544-573) Head: Prof. habil. ANDREA FACSKÓ, M.D., Ph.D. Department of Orthopedics (ORTOPÉDIAI KLINIKA) (Szeged, Semmelweis u. 6. Tel.: + 36 62 545-423, Fax: + 36 62 545-418) Head of Department: Prof. habil. KÁLMÁN TÓTH, M.D., Ph.D. Central Physiotherapeutic Unit and Educational Group (KÖZPONTI FIZIOTERÁPIÁS RÉSZLEG ÉS OKTATÁSI CSOPORT) Head: Dr. TAMÁS BENDER, M.D., Ph.D. Department of Oto-Rhino-Laryngology and Head-Neck Surgery (FÜL, ORR, GÉGÉSZETI ÉS FEJ-NYAKSEBÉSZETI KLINIKA) (Szeged, Tisza Lajos körút 111. Tel.: + 36 62 545-310, Fax: + 36 62 545-848) Head: Dr. habil. LÁSZLÓ RÓVÓ, M.D., Ph.D. Department of Pathology (PATHOLOGIAI INTÉZET) (Szeged, Állomás u. 2. Tel.: + 36 62 545-148, 545-878, Fax: + 36 62 545-868) Head of Department: Prof. habil. BÉLA IVÁNYI, M.D., D.Sc. Department of Pediatrics and Child Health Center (GYERMEKGYÓGYÁSZATI KLINIKA ÉS GYERMEKEGÉSZSÉGÜGYI KÖZPONT) (Szeged, Korányi fasor 14-15. Tel.: + 36 62 545-330 Fax: + 36 62 545-329) Head: Dr. CSABA BERECKI, M.D., Ph.D.


17

Department of Pediatrics Child Health Center Outpatient Department Section D (GYERMEKGYÓGYÁSZATI KLINIKA ÉS GYERMEKEGÉSZSÉGÜGYI KÖZPONT “D“ RÉSZLEG GYERMEK- ÉS IFJÚSÁGPSCHICHIÁTRIAI OSZÁLY) (Szeged, Boldogasszony sugárút 15. Tel.: + 36 62 545-052, Fax: + 36 62 545-049) Head: Dr. ÁGNES VETRÓ Department of Psychiatry (Pszichiátriai Klinika) (Szeged, Kálvária sgt. 57.) Head of Department: Prof. habil. JÁNOS KÁLMÁN, M.D., Ph.D., D.Sc. Psychiatry Unit I. (I. sz. PSZICHIÁTRIAI OSZTÁLY) (Szeged, Kálvária sgt. 57., Tel.: + 36 62 490-590) Head of Unit: Dr.ISTVÁN BONCZ, M.D., Ph.D. Psychiatry Unit II. (II.sz. PSZICHIÁTRIAI OSZTÁLY) (Szeged, Kálvária sgt. 57., Tel.: + 36 62 490-590/307, Fax: + 36 62 490-760/376) Head of Unit: Dr.ILDIKÓ DEMETER, M.D. Psychiatry Unit III. (III.sz. PSZICHIÁTRIAI OSZTÁLY) (Szeged, Pulz u.1., Tel.: + 36 62 545-376) Head of Unit: Dr.RÓBERT TARI, M.D. Psychiatric Rehabilitation Unit (PSZICHIÁTRIAI REHABILITÁCIÓS OSZTÁLY) (Szeged, Leányszállás köz 2/a., Tel.: + 36 62 490-590/490, Fax: + 36 62 490-590-489) Head of Unit: Dr.ZOLTÁN KOVÁCS, M.D. Psychiatric Outpatient Unit (PSZICHIÁTRIAI SZAKRENDELÉS I.) (Szeged, Vasas Szent Péter u. 1-3., Tel.: + 36 62 574-418) Head of Unit: Dr.ISTVÁN SZENDI, M.D., Ph.D. Clinical Psychology Group (KLINIKAI PSZICHOLÓGIAI CSOPORT) (Szeged, Leányszállás köz 2/a., Tel.: + 36 62 490-590/490, Fax.: + 36 62 490-590/489) Head: Dr.TIBOR RUDISCH, Ph.D. Alzheimer’s Disease Research Group (ALZHEIMER-KÓR KUTATÓCSOPORT) (Szeged, Leányszállás köz 2/a., Tel.: + 36 62 490-590/466) Head: Prof.habil.JÁNOS KÁLMÁN, M.D., Ph.D., D.Sc. Department of Pulmonology (TÜDİGYÓGYÁSZATI TANSZÉK) (Deszk, Alkotmány u. 36. Tel./Fax: + 36 62 571-552) Head of Department: Prof. habil ATTILA SOMFAY, M.D., Ph.D. Department of Radiology (RADIOLÓGIAI KLINIKA) (Szeged, Semmelweis u. 6. Tel.: + 36 62 545-429, Fax: + 36 62 545-742) Head of Department: Prof. habil. ANDRÁS PALKÓ, M.D., Ph.D. Department of Surgery (SEBÉSZETI KLINIKA) (Szeged, Szıkefalvi-Nagy B u. 4. Tel.: + 36 62 545-444, + 36 62 545-445, + 36 62 545-446, Fax: +36 62 545-701) Head of Department: Prof. habil. GYÖRGY LÁZÁR, M.D., Ph.D., D.Sc.

Transfusiology Section (TRANSZFÚZIOLÓGIAI TANSZÉK) (Szeged, Szıkefalvi-Nagy B u. 4/b Tel.: +36 62 546-805Fax: + 36 62 545-908) Head of Department: Dr. KLÁRA VEZENDI, M.D. Ph.D.

18 Department of Traumatology (TRAUMATOLÓGIAI KLINIKA) (Szeged, Semmelweis u. 6. Tel.: + 36 62 545-531, Fax: + 36 62 545-530) Head of Department: Prof. habil. JÁNOS AURÉL SIMONKA, M.D., Ph.D. Department of Urology (UROLÓGIAI TANSZÉK) (Szeged, Kálvária sugárút 57. Tel./Fax: + 36 62 490-590/280) Head of Department: Prof. habil. LÁSZLÓ PAJOR, M.D., Ph.D. Pharmacy of the Faculty of Medicine (ORVOSKARI GYÓGYSZERTÁR) (Szeged, Szikra u. 8. Tel.: + 36 62 545-061, Tel./Fax: + 36 62 545-974) Head Pharmacist: Dr. GABRIELLA JÁNOSI, D.Pharm.

Curriculum 2014/2015 FACULTY OF DENTISTRY Department of Operative and Esthetic Dentistry (KONZERVÁLÓ ÉS ESZTÉTIKAI FOGÁSZATI TANSZÉK) (Szeged, Tisza Lajos krt. 64. Tel.: +36 62 545-299) Acting Head: Dr. MÁRK ANTAL Department of Periodontology (PARODONTOLÓGIAI TANSZÉK) (Szeged, Tisza Lajos krt. 64. Tel.: +36 62 545-292) Head: Dr. LACZKÓNÉ DR. KINGA TURZÓ Department of Prosthodontics (FOGPÓTLÁSTANI TANSZÉK) (Szeged, Tisza Lajos krt. 64. Tel.: +36 62 545-308) Acting Head: Dr. ZOLTÁN BARÁTH Department of Oral Biology and Experimental Dental Research (ORÁLBIOLÓGIAI ÉS KÍSÉRLETES FOGORVOSTUOMÁNYI TANSZÉK) (Szeged, Tisza Lajos krt. 83. Tel.: +36 62 342-541) Acting Head: Prof. habil JÁNOS MINÁROVITS MD, DSc Department of Oral Surgery (SZÁJSEBÉSZETI TANSZÉK) (Szeged, Tisza Lajos krt. 64. Tel.: +36 62 545-447, +36 62545-299) Head: Prof. habil. KATALIN NAGY D.DS., Ph.D. Department of Orthodontics and Paediatric Dentistry (FOGSZABÁLYOZÁSI ÉS GYERMEKFOGÁSZATI TANSZÉK) (Szeged, Tisza Lajos krt. 64. Tel.: +36 62 545-294) Head: Dr. EMIL SEGATTO D.DS., Ph.D.

19

20

Curriculum 2014/2015 FACULTY OF PHARMACY Institute of Clinical Pharmacy (KLINIKAI GYÓGYSZERÉSZETI INTÉZET) (Szeged, Szikra u. 8. Tel.: + 36 62 544-922, Fax: +36 62 544-921) Head of Department: Dr. habil. PÉTER DORÓ Ph.D. Institute of Drug Regulatory Affairs (GYÓGYSZERFELÜGYELETI INTÉZET) (Szeged, Eötvös u. 6. Tel./Fax: +36 62 546-115) Head of Department: Dr. habil. ILDIKÓ CSÓKA D.Pharm., Ph.D. Institute of Pharmaceutical Analysis (GYÓGYSZERANALITIKAI INTÉZET) (Szeged, Somogyi u. 4. Tel.: + 36 62 545-804, Fax: +36 62 545-806) Head of Department: Prof. habil GYÖRGY DOMBI D.Chem., Ph.D. Institute of Pharmaceutical Chemistry (GYÓGYSZERKÉMIAI INTÉZET) (Szeged, Eötvös u. 6. Tel.: + 36 62 545-562, Fax: +36 62 545-705) Head of Department: Prof. habil. FERENC FÜLÖP, D.Chem., Ph.D., D.Sc. Department of Pharmaceutical Technology (GYÓGYSZERTECHNOLÓGIAI INTÉZET) (Szeged, Eötvös u. 6. Tel./Fax: + 36 62 545-571) Head of Department: Prof. habil. PIROSKA RÉVÉSZ, D.Pharm., Ph.D., D.Sc. Department of Pharmacodynamics and Biopharmaceutics (GYÓGYSZERHATÁSTANI ÉS BIOFARMÁCIAI INTÉZET) (Szeged, Eötvös u. 6. Tel./Fax: + 36 62 545-567) Head of Department: Dr. habil. RÓBERT GÁSPÁR D.Pharm, Ph.D. Department of Pharmacognosy (FARMAKOGNÓZIAI INTÉZET) (Szeged, Eötvös u. 6. Tel.: + 36 62 545-558, Fax: +36 62 324-177) Head of Department: Prof. habil. JUDIT HOHMANN D.Chem., Ph.D., D.Sc.

21

22 LIST OF EDUCATIONAL ADVISORS AND RESEARCH CONSULTANTS Research at the bench or on a clinical basis provides a very important perspective for future physicians. It gives the students a chance to pursue common goals with faculty mentors and may give a glimpse into potential careers. Students are strongly encouraged to consider research opportunities. See your scientific research consultant at each department. FACULTY OF MEDICINE Department Dept. of Anatomy, Histology and Embryology Medicine and Dentistry:

Educational advisor

Research consultant

Dr. Czigner Andrea +36 62/545 056

Dr. Annamária Kovács

[email protected] Pharmacy:

Dr. Süle Zoltán +36 62/545 734

[email protected] Dept. of Anesthesiology and Intensive Therapy

Dr. Szegesdi Ilona +36 62/545 173

Dept. of Behaviour Sciences

Dr. Bettina Pikó +36 62/545 968

Dr. László Praefort

[email protected] -Medicine:

Dr. Katalin Barabás

[email protected] Dentistry and Pharmacy:

Csaba Hamvai +36 62/545 968


[email protected] Dept. of Biochemistry

Dr. Anikó Görbe +36 62/342-810

Dr. Tamás Csont

[email protected] Department of Cell Biology and Molecular Medicine Dr. Ádám Légrádi +36 62/544-000/2296

Dr. Ádám Légrádi

[email protected] Department of Clinical Microbiology

Dr. Gabriella Terhes +36 62/545 888

Dr. Gabriella Terhes

[email protected] Dept. of Laboratory Medicine

Dr. Rita Ónody +36 62/545 753

Dept. of Surgery

Prof. Dr. András Petri +36 62/545 445

Dept. of Dermatology and Allergology

Dr. Zsuzsanna Bata +36 62/545 996

Dr. Rita Ónody

[email protected] Dr. Zsolt Simonka

[email protected] Dr. Kornélia Szabó

[email protected] 1st Department of Internal Medicine

Dr. András Rosztóczy +36 62/545 195

Dr. Tamás Takács

[email protected] 2nd Department of Internal Medicine - Cardiology: Dr. Gábor Bencsik

[email protected] +36 62/544 901 - Hematology: Dr. Tímea P. Gurbity + 36 62/545 226 Dept. of Forensic Medicine

Dr. Beáta Havasi +36 62/342-910

Institute of Foreign Languages

Vanda Varga +36 62/425-521

Dr. Beáta Havasi

[email protected] [email protected]

Izabella Villányi


23

Institute of Surgical Research

Dr. Andrea Szabó +36 62/545 106

Dept. of Medical Biology

Dr. Dóra Tombácz +36 62/542 384

Dept. of Medical Chemistry

Dr. Györgyi Váradi +36 62/545 136

Dept. of Medical Genetics

Dr. Zsuzsanna László +36 62/546 127

Dept. of Medical Physics and Informatics

Dr. Ferenc Peták +36 62/545 832

Dr. József Kaszaki

[email protected] Dr. István Belecz

[email protected] Dr. Lajos Kovács

[email protected] Dr. Nikoletta Nagy

[email protected] Dr. Ferenc Peták

[email protected] Dept. of Medical Microbiology and Immunobiology Medicine: Dr. Zoltán Tiszlavicz +36 62/342 840 [email protected] Dentistry: Dr. Béla Prágai +36 62/545 920

Dr. András Miczák

[email protected] Dept. of Neurology

Dr. János Tajti +36 62/545 355

Dept. of Neurosurgery

Dr. Zsolt Kopniczky +36 62/545 383 or 71-154

Dept. of Nuclear Medicine

Dr. Miklós Papós +36 62/545 736

Dept. of Obstetrics and Gynecology

Dr. Zoltán Borthaiser +36 62/545 518

Dr. János Tajti

[email protected] Dr. Pál Barzó

[email protected] Dr. Miklós Papós

[email protected] Dr. György Bártfai

[email protected] Dr. Gábor Németh +36 62/545 522, 545 757

[email protected] Dept. of Oncotherapy

Dr. Gabriella Fábián +36 62/545 403

Dr. Anikó Maráz

[email protected] Dept. of Ophthalmology

- Medicine:

- Dentistry:

Prof. Dr. Andrea Facskó Dr. Edit Tóth-Molnár Dr. Goran Petrovski +36 62-545-487 [email protected] Dr. Rózsa Dégi +36 62/ 545 778, 544 933

Prof. Andrea Facskó

[email protected] Dept. of Orthopedics

Dr. Péter Kellermann +36 62/541 314

Dept. of Oto-Rhino-Laryngology - Medicine:

Dr. Miklós Csanády +36 62/545 317

- Dentistry:

Dr. Smehák György +36 62/545 317

- Medicine:

Dr. Levente Kuthi +36 62/546 176

- Dentistry:

Dr. Bence Kıvári +36 62/546 176

Dr. László Tajti

[email protected] [email protected] [email protected] Dept. of Pathology

[email protected]

Dr. Birinyiczki Kitti

24

[email protected] Dept. of Pathophysiology

– Medicine:

Dr. Zsófia Mezei +36 62/545 111

- Dentistry:

Dr. Júlia Szakács +36 62/545 993

Dr. Miklós Jászberényi

[email protected] [email protected] - Pharmacy:

Dr. Zsolt Bagosi +36 62/545 789

[email protected] Dept. of Pediatrics

Dr. Ágnes Maróti +36 62/545 5330

Dr. Eszter Karg

[email protected] Dentistry:

Dr. Dániel Szőcs +36 62/545 5330

[email protected] Dept. of Child and Adolescent Psychiatry

Dr. Dochnal Roberta Beatrix

Dr. Dochnal Roberta Beatrix

+36 62/549 635

[email protected] Dept. of Pharmacology and Pharmacotherapy

Dr. János Pataricza +36 62/545 674

Dr. István Baczkó

[email protected] Dept. of Physiology Medicine and Dentistry:

Dr. Ferenc Domoki +36 62/545 100

Dr. Ferenc Domoki


Dr. Gyöngyi Horváth +36 62/544 971

[email protected] Dept. of Psychiatry

Dr. János Kálmán +36 62/490 590

Dr. János Kálmán

[email protected] Dr. Horváth Szatmár +36 62/545 944

[email protected] Dept. of Public Health (Public Health) Medicine and Dentistry:

Dr. Andrea Szabó +36 62/342 869

Dr. András Papp


Dr. Zsuzsanna Máté +36 62/342 866

[email protected] Dept. of Public Health (Medical Sociology)

Dr. Regina Molnár +36 62/342 872

Dept. of Pulmonology

Dr. Edit Csada +36 62/571 552

Dept. of Radiology

Dr. Endre Nagy +36 62/545 438

Dr. Regina Molnár

[email protected] Dr. Edit Csada

[email protected] Dr. Erika Vörös

[email protected] 2nd Department of Internal Medicine

Dr. Szabolcs Modok +36 62/545 226

Dept. of Traumatology

Dr. Endre Varga +36 62/545 537

Dept. of Urology

Dr. István Papos +36 62/541 918

Dr. Zita Borbényi

[email protected] Dr. Sándor Pintér

[email protected] [email protected]

Dr. Olivér Pintér


25

FACULTY OF DENTISTRY Educational advisor Dr. Anette Stájer +36 62/545 298

[email protected]

FACULTY OF PHARMACY Department Institute of Drug Regulatory Affairs

Educational advisor Dr. Ildikó Csóka +36 62/546 162

[email protected] Institute of Clinical Pharmacy

Dr. Péter Doró +36 62/544 944

Institute of Pharmaceutical Analysis

Dr. Gerda Szakonyi +36 62/545 925, 545-804

Institute of Pharmaceutical Chemistry

Dr. Márta Palkó

Department of Pharmaceutical Technology

Dr.Erzsébet Csányi +36 62/545 573

Department of Pharmacodynamics and Biopharmacy

Dr. Eszter Ducza +36 62/541-977

Department of Pharmacognosy

Dr. Katalin Veres +36 62/546 451

[email protected] [email protected] [email protected] [email protected] [email protected] [email protected]

Research consultant Prof. Zoltán Rakonczay +36 62/545 301

26 ACADEMIC CALENDAR Faculty of Medicine Faculty of Dentistry Faculty of Pharmacy 2014/2015

ACADEMIC PERIODS 1st semester Education period: September 01 – December 06, 2014 Examination period: December 08 – December 23, 2014 and January 05 – January 24, 2015 Repeat examination period: January 26 – January 31, 2015 Winter break: December 24, 2014 – January 04, 2015 (School is closed: No exams.) Holidays: October 23, 2014 and November 01, 2014 2nd semester Education period: February 02 – May 16, 2015 Examination period: May 18 – June 27, 2015 Repeat examination period: June 29 – July 04, 2015 Spring break: April 07-April 11, 2015 Holidays: April 06, 2015 and May 01, 2015

For other important dates and deadlines please check the relevant Info Sheet, our website or the Clerkship Guide.


27 FEES

1. Tuition fees Fees are subject to change in case the students’ academic progress does not follow the suggested study plan. Minimum tuition fee can be determined by the Academic Board. Fee of attending three or more compulsory subjects/Hungarian Language/Latin Language Fee of attending two compulsory subjects/Hungarian Language/Latin Language Fee of attending one compulsory subject/Hungarian Language/Latin Language Exam course fee Fee of Compulsory Elective Courses/Elective Courses/Physical Education (in case of attending one or two compulsory courses/Hungarian Language/Latin Language) Payment can be made the following ways: • by transfer • by cash: you have to pick up a slip at the Foreign Students' Secretariat in order to be able to pay in cash at the MKB Bank. • by check: the checks have to be handed in at the Foreign Students' Secretariat.

100% of one semester’s tuition fee 60% of one semester’s tuition fee 40% of one semester’s tuition fee 570 USD/course 5% of one semester’s fee/course

tuition

Account: University of Szeged Hungarian Foreign Trade Bank (MKB), Szeged, Kölcsey u. 8 Swift code: MKKBHUHB IBAN: HU14-1030-0002-6610-3177-2700-4013

2. Procedural fees Repeat examination fee • on the first occasion • on the second occasion Procedural fee for further requests (Deans’ permission) Fee for improving a successful examination State Board Examination fee Fee for repeating the State Board examination Fee for repeating the Thesis defense • on the first occasion • on the second occasion • procedural fee for further requests

HUF 1 000 HUF 1 500 HUF 3 000 HUF 500 USD 300 USD 250 HUF 7 500 HUF 15 000 HUF 15 000

3. Administrative fees • loss of the index book and providing a duplicate first occasion further occasions • transcript • certificate • syllabus • ETR Late course registration (only possible in the week after the course registration deadline) • missing other deadlines

HUF HUF HUF HUF HUF HUF

5 000 10 000 400/semester 300 400/year 5 000/subject

HUF 10 000 in the first week, after that additional HUF 2000/week

28

Fees are subject to change. For updates please check the relevant Info Sheet.


29 GENERAL GUIDELINES

1.) Registration: Students have to register for each semester in order to have an active student status. Students who are not registered properly are not entitled to attend the classes. LATE REGISTRATION IS NOT POSSIBLE. Registration requirements: • Tuition fee has to be credited to the University’s bank account in full before registration. • ETR registration form (to be signed at the Secretariat) • Valid residence permit. Please check in the ETR (under MY DATA/PERSONAL DATA/IDENTIFIERS) whether you have submitted a copy of your valid residence permit. If it was renewed recently please present the original and a copy to the Secretariat. • Valid health insurance (If it was renewed recently please present the original and a copy to the Secretariat. If you contract the Generali Providencia insurance you do not have to bring a copy). • Index book (with all signatures and grades) • Summer practice evaluation sheet (if required) • NEW! Paid repeat examination ticket •

NEW! Valid Medical Fitness Certificate (completed medical check-up by the University Doctor) You will be notified via e-mail in case any part of the medical check up has been found insufficient!

2.) Payment of the tuition fee: The deadline of payment is always specified in the information sheets distributed to the students before the beginning of the upcoming semester. Proof of payment has to be submitted to the Secretariat. Students have to make sure that the exact amount of the tuition fee is credited to the University's account until the deadline. Late payment is not possible. 3.) ETR course registration: Students have to sign up for their courses in the ETR (computer-based academic system) each semester. Students failing to meet this requirement are not entitled to attend the classes. The number of course registrations in a subject is limited: one course can be registered 3 times during the period of studies. Make sure you sign up for all your courses (both the lectures and practices, examination courses, physical education -2 semesters required). 4.) Residence permit

Details: http://szegedmed.hu/residence_permit_info 5.) Health Insurance All students must have a valid health insurance during their stay in Hungary.

Details: http://www.szegedmed.hu/insurance 6.) Attendance of classes: If the absence does not exceed 15% of the total number of classes, students are not obliged to provide a certificate justifying the absence. If the absence falls between 15 and 25% of the total number of classes, students may only make up for the missed classes if they provide a certificate.The departments have the right to refuse the acceptance of a semester if the student missed more than 25 % of the practicals and did not make up for the absences. 7.) Obligation to report changes to the Secretariat: If there is a change in your personal data (address, e-mail address, telephone number etc.) you are required to notify the Secretariat and correct the data in the ETR. If you have to leave Szeged for a longer period of time during the lecture period due to substantial reasons (hospitalization, extraordinary family issues), you need to request permission in writing. Applications have to be handed in at the Foreign Students’ Secretariat. 8.) General information regarding the examinations: General information before you sign up for your exams: • One course can be taken 3 times during your studies (3 exams/semester). • All exams including date, time and place is posted in the ETR. Make sure to arrive for your exam on time with your index book. • Exam dates can be postponed before the ETR closes the registration (usually 24 hours before the date of the exam. Clicking the course code, one can determine the closing of registration.) However, it is your duty to secure another date and time for your exam when you make changes.

• •

30 Students not showing up on an exam will lose one chance unless their absence is justified. Documents justifying the absence have to be presented at the Department concerned. To get the ticket to your next examination, please see the fee schedule below. A successful examination can be improved only in one subject / semester and only with the permission of the Program Director. The requests have to be handed in at the Foreign Students’ Secretariat.

In order to receive your index book for the exam period you have to meet all the following requirements: • Paid tuition fee, valid matriculation, valid health insurance, and valid visa/residence permit. • Please note that Hungarian law (2007. II. Törvény) requires Non-EU Students to be fully covered under a health insurance plan or be able to cover the expenses of their health care. EU citizens are supposed to register with BÁH upon their arrival and submit a photocopy of their health insurance (2007. I. Törvény) Please make sure to register for all your exams at the beginning of the exam registration period. Index book can be picked up from the Secretariat upon signing a consent form. Students are required to return their index book to the Secretariat upon finishing their exams. Procedures for unsuccessful exams: • Repeated exam can be scheduled at the earliest by the 3rd day following the unsuccessful exam. Repeat exam cheques are available at the Secretariat. Fees have to be paid at the post office and slips have to be returned to the Secretariat in order to get repeat tickets. The repeat ticket has to be presented at the Department before starting the examination. The current fee schedule is: • Unsuccessful exams can be repeated 2 times during the exam period. Upon request, a repeated exam can be taken before a committee. The exam committee is appointed by the Department Chair. Repeated exams with committee can be scheduled only for exam dates announced in the ETR. • 3rd repeat chance can be granted to those who have only one exam left. (In these cases the chances should be decreased by one when students sign up for the course for the 3rd time). Request have to be handed in at the Foreign Students’ Secretariat. • In case of even one unjustified absence in an examination the student will not be entitled to any further equities and exceptional permissions in any subject in the respective examination period (e.g. 3rd repeat examination chance). • In the repeat examination period only repeated exams can be taken. First examinations – even with a former absent registration – cannot be taken in the repeat examination week! • In exceptional cases (hospitalization, extraordinary family issues) further examination chances can be requested from the Dean. Examinations granted as an exceptional equity can be taken only till the end of second week following the repeat examination period. Supporting documents must be attached to the application. Please take into consideration that all matters not regulated in the Study and Examination Regulations will be evaluated on individual basis by the Academic Board (eg. 4th course registration)!

Further details are available in the relevant Info Sheet.


31 EXPRESSIONS

Compulsory Elective Subject (including Behavioral Science Subjects – only for medical students): There is a given number of credit points that has to be acquired in Compulsory Elective Subjects in the certain modules. One can choose freely from the subjects offered, however it is strongly recommended to follow the Suggested Study Plan. Compulsory Subject: It is obligatory to take the subject in the module given. Contact hours: Contact hours are the units of time required for a teacher to present subject material and to assess a student’s performance. Contact hours include lectures, seminars, practical demonstrations, consultation hours and assessment. Course requirement: The course requirement defines the precondition of a certain course. The course requirement can either be a subject or an examination requirement. In case of the subject requirement a course can be signed up for only if the examination defined in the course requirement has been completed successfully. In case of the examination requirement the examination of a course can only be taken if the examination defined in the course requirement has been completed successfully. Credit: Credits are standard measurement of a student’s accepted study time. One credit equals thirty hours of study time. Credit transfer: Is a procedure accorded by the University of Szeged Code of Study and Examination Regulations, whereby a partial or full exemption can be given from completing one or more subjects by acknowledging previously completed subjects and thereby award the appropriate number of credit points. Criteria Subject: Completion of criteria subjects is a precondition for entering the next module or receiving the diploma after finishing the final year (Physical Training, Summer Practices, Hungarian Language). Criteria subjects have no credit allocated to. Elective Subject: There is a given number of credit points that has to be acquired in the certain modules. One can chose freely from the subjects offered, however it is strongly recommended to follow the Suggested Study Plan. Examination course: If one cannot pass an examination successfully in the semester given, the examination can be repeated in the next examination period if the Department concerned announces it in the given semester and you get permission from the Academic Board. This means that the student will be exempted from fulfilling the requirements of the semester (classes do not have to be attended). An examination course can be taken only once in a certain subject. Suggested study plan: the order and timing of subjects offered to students enabling them to obtain qualification within a specified period of time.

Grading system

Five-grade system 5 4 3 2 1

-

excellent good accepted passed failed

32


33

Faculty of Medicine

34 GENERAL INFORMATION REGARDING THE STRUCTURE OF STUDIES AT THE FACULTY OF MEDICINE FOR THOSE WHO STARTED THEIR STUDIES IN THE ACADEMIC YEAR 2013/2014 OR LATER I. STRUCTURE OF STUDIES In the academic year 2014/2015, first year students follow the new Curriculum / Suggested Study Plan of University of Szeged, Faculty of Medicine. In order to obtain the Doctor of Medicine diploma, students need to acquire a minimum of 360 credits (by fulfilling the study and examination requirements of the subjects listed in the suggested study plan). In the final year, students, furthermore, have to complete the Final (State Board) Examination which consists of writing and defending a thesis, passing a complex written test and an oral patient examination (theoretical and practical part). The order of taking the courses is set in the suggested study plan which is designed for completing medical studies within 12 semesters (6 years). It is highly recommended to take the courses according to the Suggested Study Plan. Teaching is performed in 3 modules:

Basic & Pre-Clinical Module (1st, 2nd, 3rd year) Clinical Module (4th, 5th year) Final Module (6th year)

Types of courses:

Compulsory Courses Compulsory Elective Courses Elective Courses Criteria Subjects

Credits to be acquired:

Basic & Pre-Clinical Module (semesters 1-6)

Compulsory Courses Compulsory Elective Courses Elective Courses Criteria Subjects (no credits)

Clinical Module (semesters 7-10) Credits 104

145 45 18 Physical Education, Hungarian Language, Summer Practice

Hungarian Language, Summer Practice

All the requirements of a module have to be fulfilled in order to enter the next module.

Final Module (semesters 11-12)

60


35

II. SPECIAL RULES FOR BEHAVIORAL SCIENCE SUBJECTS In the fourth year (7th semester), students have to take a final examination which covers the knowledge, skills and attitudes learned during the seven previous semesters. The precondition for taking the examination is the earlier acquisition of 13 credits from the subjects below. However, it is recommended to complete all Behavioral Science Subjects (15 credits).

Recommended schedule for acquiring 13 credits: • 8 credits for compulsory subjects: Introduction to Psychology, basics of nursing Communication skills (2 credits, year 1, spring semester) Medical Ethics (3 credits, year 3, spring semester) Medical Psychology I. (2 credits, year 3, spring semester) Medical Psychology II. (1 credit, year 4, fall semester) • 5 credits for compulsory elective subjects. You can choose from the following courses: Introduction to Medicine (2 credits, year 1, fall semester) Medical Sociology (2 credits, year 2, fall semester) Medical Anthropology (1 credit, year 2, spring semester) Gerontology (2 credits, year 3, spring semester) • Criteria subject: Doctor-Patient Communication (0 credit, criteria subject; year 4, fall or spring semester)

36 GENERAL INFORMATION REGARDING THE CREDIT SYSTEM AT THE FACULTY OF MEDICINE FOR THOSE WHO HAVE STARTED THEIR STUDIES BEFORE THE ACADEMIC YEAR 2013/2014

I. STRUCTURE OF STUDIES Students have to complete 4 modules in order to obtain the Doctor of Medicine diploma. All the requirements of a module have to be fulfilled in order to enter the next module: • acquisition of the required credits • completion of Criteria Subjects: - 2 semesters of Physical Training till the end of the 12th semester (It is recommended to complete it in the Basic Module) - Summer practices (Nursing, Internal Medicine, Surgery) - 8 semesters of Hungarian Language Behavioral Science Subjects: In the fourth year (7th semester) students have to take a final examination which covers the knowledge, skills and attitudes learned during the seven previous semesters. The precondition for taking the examination is the earlier acquisition of 10 credits from the subjects below. However, it is recommended to complete all Behavioral Science Subjects (13 credits). Recommended schedule for acquiring 13 credits: • 8 credits for compulsory subjects: Introduction to Psychology, basics of nursing (0 credit, year 1, spring semester) Communication skills (3 credits, year 1, spring semester) Medical Ethics (2 credit, year 3, spring semester) Medical Psychology I. (2 credits, year 3, spring semester) Medical Psychology II. (1 credit, year 4, fall semester) • 5 credits for compulsory elective subjects. You can choose from the following courses: Introduction to Medicine (2 credits, year 1, fall semester) Medical Sociology (2 credits, year 2, fall semester) Medical Anthropology (1 credit, year 2, spring semester) Gerontology (2 credits, year 3, spring semester) + Doctor-Patient Communication (0 credit, criteria subject; year 4, fall or spring semester)

II. MODULES:

1. BASIC MODULE In the Basic Module (years 1-2, semesters 1-4) one has to acquire 117 credits in order to enter the PreClinical module. Credits have to be acquired according to the following scheme: Required credits: • Compulsory Subjects (94 credits) • Compulsory Elective Subjects (17 credits) • Elective Subjects (6 credits) • Criteria Subjects (Nursing Summer Practice – to be completed after the 2nd semester, 4 semesters of Hungarian Language) It is also recommended to complete 2 semesters of Physical Education in the Basic Module.


37

Preconditions for enrollment to the forthcoming semesters: •

The compulsory courses in the second semester have examination requirements. This means one can take the examination of the second semester course only if the examination of the first semester subject (defined in the examination requirement) has been completed successfully: Course Anatomy II. Medical Chemistry II. Medical Physics II. Medical Biology II.

Examination requirement Anatomy I. Medical Chemistry I. Medical Physics I. Medical Biology I.

The first semester courses might be taken as examination courses in the second semester, if the Department concerned announces it in the given semester and if you get permission from the Academic Board. This means that the student will be exempted from fulfilling the study requirements (classes do not have to be attended). An examination course can be taken only once in a certain subject. If one fails to complete an examination course both the study and examination requirements have to be completed in the proper semester (the whole course has to be repeated by attending the lectures and practices). •

The compulsory courses in the third semester have subject requirements. This means one can attend a third semester course only if the examination of the second semester (defined in the subject requirement) has been completed successfully: Course Anatomy III. Biochemistry I. Physiology I.

Subject requirement Anatomy II. Medical Chemistry II. Medical Chemistry II.

In this case the failed examination of the second semester can be repeated as an examination course in the semester when it is announced by the Department concerned. •

The compulsory courses in the fourth semester have examination requirements. This means one can take the examination of the fourth semester course only if the examination of the third semester (defined in the examination requirement) has been completed successfully: Course Anatomy IV. Biochemistry II. Physiology II.

Examination requirement Anatomy III. Biochemistry I. Physiology I.

For further conditions see the requirements of the second semester.

2. PRE-CLINICAL MODULE In the Pre-Clinical Module (year 3, semesters 5-6) one has to acquire 56 credits in order to enter the Clinical module. Credits have to be acquired according to the following scheme: Required credits: • Compulsory Subjects (45 credits) • Compulsory Elective Subjects (8 credits) • Elective Subjects (3 credits) • Criteria Subjects (Internal Medicine Summer Practice – to be completed after the 6th semester, 2 semesters of Hungarian Language)

38 Preconditions for enrollment to the forthcoming semester: •

The compulsory courses in the second semester have subject requirements. This means one can take the second semester course only if the first semester course has been completed successfully: Course Pathophysiology II. Microbiology and Immunology II. Pathology II. Internal Medicine I.

Subject requirements Pathophysiology I. Microbiology and Immunology I. Pathology I. Clinical Diagnostics I.

If one fails to complete the first semester course both the study and examination requirements have to be completed in the proper semester (the whole course has to be repeated).

3. CLINICAL MODULE In the Clinical Module (years 4-5, semesters 7-10) one has to acquire 132 credits in order to enter the Final module. Credits have to be acquired according to the following scheme: Required credits: • Compulsory Subjects (106 credits) • Compulsory Elective Subjects (18 credits) • Elective Subjects (8 credits) • Criteria Subjects (Surgery Summer Practice – to be completed after the 8th semester, 2 semesters of Hungarian Language, Doctor-Patient Communication) Preconditions for enrollment to the forthcoming semester: You can find the subject requirements in the suggested study plans for the certain semesters.

4. FINAL MODULE – CLERKSHIP YEAR In the Final Module (year 6, semesters 11-12) one has to acquire 60 credits in order to be eligible to sit for the State Board Examination.


37 Hrs/week: Practice

Form of exam

Credit

Course Code

Hrs/week: Theory

SUGGESTED STUDY PLAN Course Requirement (SR=Subject requirement; ER=Examination requirement; P=Parallel Completion)

2 -

3 2 2

Examination Term Mark(5) Signature Term Mark(5)

5 3 2

P:AOK-KUA011 P:AOK-KUA012 -

3

-

Examination

4

-

Gábor Tóth Gábor Tóth Zsolt Boldogkıi Zsolt Boldogkıi

3 2 -

2 3 2

Signature Examination Signature Examination Signature

6 4 -

P:AOK-KUA051 P:AOK-KUA061 P:AOK-KUA-071

Dept. of Med. Biology Dept. of Med. Physics and Informatics

Prof. Zsolt Boldogkıi Prof. Ferenc Bari

1 -

2

Evaluation(5)

1 2

-

Dept. of Cell Biology and Molecular Medicine

Prof. Károly Gulya

2

-

Dept. of Med. Biology Dept. of Med. Biology Dept. of Med. Biology Dept.of Behavioural Sciences Dept.of Behavioural Sciences

Prof. Zsolt Boldogkıi Prof. Zsolt Boldogkıi Prof. Zsolt Boldogkıi Dr. Katalin Barabás Dr. Katalin Barabás

Course

Department

Head of Department

MEDICINE BASIC AND PRE-CLINICAL MODULE 2014/2015 1st year, 1st (fall) semester (9001AK_N_2013) Compulsory Subjects AOK-KUA011 AOK-KUA012 AOK-KUA013 AOK-KUA041

Anatomy, Histology and Embryology I. Dissection Practice I. Anatomy Seminar Basic Life Support

AOK-KUA051

Medical Physics and Statistics I.

AOK-KUA052 AOK-KUA061 AOK-KUA062 AOK-KUA071 AOK-KUA072 AOK-KA1311 AOK-KA1801

Medical Physics and Statistics I. Medical Chemistry I. Medical Chemistry I. Cell Biology and Molecular Genetics I. Cell Biology and Molecular Genetics I. Compulsory Elective Subjects Basics in Molecular Biology Biostatistical Calculations

AOK-KA1891

Cytomorphology and Microtechnics

AOK-KA091 AOK-KA1321 AOK-KA101 AOK-KA601 AOK-KA602

Developmental Genetics I. Frontiers of Molecular Biology Genetic Analysis I. Introduction to Medicine Introduction to Medicine

Dept. of Anatomy Dept. of Anatomy Dept. of Anatomy Dept. of Traumatology Dept. of Med. Physics and Informatics

Prof. Prof. Prof. Prof. Prof.

Dept. of Med. Physics and Informatics

Prof. Ferenc Bari

Dept. Dept. Dept. Dept.

Prof. Prof. Prof. Prof.

of of of of

Med. Med. Med. Med.

Chemistry Chemistry Biology Biology

András Mihály András Mihály András Mihály Endre Varga Ferenc Bari

Term Mark(5)

1 2 1 1 -

1

2 Evaluation(5) Evaluation(5) Evaluation(5) Evaluation(5) Evaluation(5) Signature

1 2 1 2 -

P:AOK-KA601

Credit

AOK-KUA251 XT0011-PHE

Elective Subjects Medical Latin Language I. Criteria Subjects Hungarian Language I.* Physical Education (P.E.)**

Head of Department

Form of exam

AOK-KA391

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

38

Dept. of Foreign Lang.

Dr. Éva Demeter

-

2

Term Mark(5)

2

Dept. of Foreign Lang. Sport Center

Dr. Éva Demeter Andrea Böröcz Hézsıné

-

4 2

Term Mark(5) Signature

-

Department

* The completion of the course is obligatory in the semester given. ** One has to complete 2 semesters of Physical Education until the end of the 5th year.

Course Requirement (SR=Subject requirement; ER=Examination requirement; P=Parallel Completion)

-


39

Form of exam

Credit

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

SUGGESTED STUDY PLAN

Dept. of Anatomy Dept. of Anatomy

Prof. András Mihály Prof. András Mihály

2 -

3

Examination Term Mark(5)

3 3

Dept. of Anatomy

Prof. András Mihály

-

2

Term Mark(5)

2

Dept. of Traumatology Dept. of Med. Physics and Informatics Dept. of Med. Physics and Informatics Dept. of Med. Chemistry Dept. of Med. Chemistry Dept. of Med. Biology Dept. of Med. Biology Dept.of Behavioural Sciences Dept.of Behavioural Sciences

Prof. Endre Varga Prof. Ferenc Bari

3

2 -

Term Mark(5) Examination

1 4

Prof. Ferenc Bari

-

2

Signature

-

Prof. Gábor Tóth Prof. Gábor Tóth Prof. Zsolt Boldogkıi Prof. Zsolt Boldogkıi Dr. Katalin Barabás Dr. Katalin Barabás

3 2 1 -

3 2 2

Examination Signature Examination Signature Signature Term Mark(5)

6 4 2

Prof. Prof. Prof. Prof. Prof. Prof. Prof.

1 1 2 1 1 1

1 -

Evaluation(5) Evaluation(5) Evaluation(5) Evaluation(5) Evaluation(5) Signature

1 1 2 1 2 3

Department

Head of Department


MEDICINE BASIC AND PRE-CLINICAL MODULE 2014/2015 1st year, 2nd (spring) semester (9001AK_N_2013) Compulsory Subjects AOK-KUA014 AOK-KUA015

Anatomy, Histology and Embryology II.

AOK-KUA016

Dissection Practice II. Histology Practice I.

AOK-KUA042 AOK-KUA053

Basic Life Support II. Medical Physics and Statistics II.

AOK-KUA054

Medical Physics and Statistics II.

AOK-KUA063 AOK-KUA064 AOK-KUA073 AOK-KUA074 AOK-KA1901 AOK-KA1902

Medical Chemistry II. Medical Chemistry II. Cell Biology and Molecular Genetics II. Cell Biology and Molecular Genetics II. Introduction to Psychology, basics of nursing Communication Skills Compulsory Elective Subjects Basics in Molecular Biology Developmental Genetics II. Frontiers in Molecular Biology Genetic Analysis II. Introduction to Chemistry Introduction to Chemistry Introduction to Medical Informatics

AOK-KA1312 AOK-KA092 AOK-KA1322 AOK-KA102 AOK-KA1231 AOK-KA1232 AOK-KA081

Dept. of Med. Dept. of Med. Dept. of Med. Dept. of Med. Dept. of Med. Dept. of Med. Dept. of Med. Informatics

Biology Biology Biology Biology Chemistry Chemistry Physics and

ER: AOK-KUA011 P:AOK-KUA011, AOKKUA014 P:AOK-KUA011, AOKKUA015 ER: AOK-KUA041 ER: AOK-KUA051

Zsolt Boldogkıi Zsolt Boldogkıi Zsolt Boldogkıi Zsolt Boldogkıi Gábor Tóth Gábor Tóth Ferenc Bari

Evaluation(5)

P: AOK-KUA053 ER: AOK-KUA061 P: AOK-KUA063 ER: AOK-KUA071 P: AOK-KUA073 P:AOK-KA1231 -

Introduction to Medical Informatics

AOK-KA151 AOK-KA121

Modern Instrumental Analysis and Separation Methods Neurocytology

AOK-KA161 AOK-KA392 AOK-KUA261 AOK-KUA252 XT0011-2PHE AOK-KUA211

Steric Strucure of Biopolimers Elective Subjects Medical Latin Language II.* Chemical Misconceptions Criteria Subjects Hungarian Language II.* Physical Education (P.E.)** Nursing Practice

Head of Department

Credit

AOK-KA082

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

40

-

2

Signature

-



Prof. Ferenc Bari

Dept. of Med. Chemistry Dept. of Anatomy Dept. of Med. Chemistry

Prof. Gábor Tóth Prof. András Mihály

1 2

-

Evaluation(5) Evaluation(5)

1 2

-

Prof. Gábor Tóth

1

-

Evaluation(5)

1

-

Dept. of Foreign Lang. Dept. of Med. Chemistry

Dr. Éva Demeter Prof. Gábor Tóth

2

2 -

Term Mark(5) Evaluation (5)

2 2

SR: AOK-KA391


Dr. Éva Demeter

-

4 2 4x30

Term Mark(5) Signature Signature

-

SR: AOK-KUA251

Andrea Böröcz Hézsıné

P:AOK-KA081

* The completion of the course is obligatory in the semester given. **One has to complete 2 semesters of Physical Education until the end of the 5th year.

-

-


41


2

-

Dept. of Anatomy


-

3

Head of Department

Credit

Dept. of Anatomy

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


3

SR:AOK-KUA014

3

MEDICINE BASIC AND PRE-CLINICAL MODULE 2014/2015 2nd year, 3rd (fall) semester (9001AK_N_2013) Compulsory Subjects AOK-KUA017

Anatomy, Histology and Embryology III.

AOK-KUA018 AOK-KUA019 AOK-KUA021 AOK-KUA022 AOK-KUA031 AOK-KUA032

Dissection Practice III. Histology Practice II.

Comprehensive Exam

6 8 -

P:AOK-KUA017, AOKKUA019 P:AOK-KUA017, AOKKUA018 SR:AOK-KUA063 P:AOK-KUA021 SR:AOK-KUA063 P:AOK-KUA031

Term Mark(5) Dept. of Anatomy

Biochemistry I. Dept. of Biochemistry Biochemistry I. Dept. of Biochemistry Medical Physiology I. Dept. of Physiology Medical Physiology I. Dept. of Physiology Compulsory Elective Subjects AOK-KA351N Medical Physiology (Seminar) I. Dept. of Physiology AOK-KA1631 Biochemistry Seminar I. Dept. of Biochemistry AOK-KA871 Molecular Cytology and Histology Dept. of Anatomy AOK-KA631 Medical Sociology Dept. of Public Health Elective Subjects AOK-KA1771 Body Development and Diseases and a Molecular Dept. of Biochemistry Biological Background AOK-KA99031 Animal Experiments in Medicine Inst. of Surgical Research Criteria Subjects AOK-KUA253 Hungarian Language III.* Dept. of Foreign Lang. XT0011-PHE Physical Education (P.E.)** Sport Center * The completion of the course is obligatory in the semester given. ** One has to complete 2 semesters of Physical Education until the end of the 5th year.


-

2

2

4 4 -

2 4

Term Mark(5) Examination Signature Examination Signature

Prof. Gyula Sáry Prof. László Dux Prof. András Mihály Dr. Edit Paulik

2 2 -

4 2

Evaluation(5) Evaluation(5) Evaluation(5) Examination

4 2 2 2


Prof. László Dux

2

-

Evaluation(5)

2

-

total 22

-

Evaluation(5)

1

-

-

4 2


-

SR:AOK-KUA252 -


László Dux László Dux Gyula Sáry Gyula Sáry

Prof. Mihály Boros Dr. Éva Demeter Andrea Böröcz Hézsıné

42

Hrs/week: Practice

AOK-KUA091 AOK-KUA092 AOK-KUA101 AOK-KUA111 AOK-KUA112 AOK-KUA023

Compulsory Subjects Microbiology I. Microbiology I. Immunology Basic Surgical Skills Basic Surgical Skills Biochemistry II.

Dept. of Med. Microbiology Dept. of Med. Microbiology Dept. of Med. Microbiology Inst. of Surgical Research Inst. of Surgical Research Dept. of Biochemistry

Dr. Katalin Burián Dr. Katalin Burián Dr. Katalin Burián Prof. Mihály Boros Prof. Mihály Boros Prof. László Dux

2 2 1 4

3 2 -

AOK-KUA024 AOK-KUA033

Biochemistry II. Medical Physiology II.

Dept. of Biochemistry Dept. of Physiology

Prof. László Dux Prof. Gyula Sáry

6

2 -

AOK-KUA034

Medical Physiology II. Compulsory Elective Subjects Human Embryology: Development of the Organ Systems Medical Physiology (Seminar) II. Biochemistry Seminar II. Cardiac Electrophysiology as a Basic Property of Cardiac Function Cardiac Electrophysiology as a Basic Property of Cardiac Function Molecular Developmental-Biology Medical Anthropology Biochemical Basics of Preventive Medicine

Dept. of Physiology

Prof. Gyula Sáry

-

4

Dept. of Anatomy


2

-

Dept. of Physiology Dept. of Biochemistry Dept. of Pharmacology

Prof. Gyula Sáry Prof. László Dux Prof. András Varró

2 1

4 -

Dept. of Pharmacology

Prof. András Varró

2 2

Course

Department

Head of Department


5 2 3 6

ER:AOK-KUA073 P:AOK-KUA091 ER:AOK-KUA073 ER:AOK-KUA017 P:AOK-KUA111 ER:AOK-KUA021

10

P:AOK-KUA023 ER:AOK-KUA031

-

P:AOK-KUA033

2

ER:AOK-KUA017

Evaluation(5) Evaluation(5) Evaluation(5)

4 2 2


1

Signature

-

-

1 -


2 1 2

-

Form of exam

Course Code

Credit

Hrs/week: Theory


MEDICINE BASIC AND PRE-CLINICAL MODULE 2014/2015 2nd year, 4th (spring) semester (9001AK_N_2013)

AOK-KUA231 AOK-KA352N AOK-KA1632 AOK-KA861 AOK-KA862 AOK-KA881 AOK-KA621 AOK-KA1221

Dept. of Biochemistry Prof. László Dux Dept.of Behavioural Sciences Dr. Katalin Barabás Dept. of Biochemistry Prof. László Dux

Exam Signature Exam Exam Signature Comprehensive Exam Signature Comprehensive Exam Signature


AOK-KUA261 AOK-KUA254 XT0011-2PHE

Credit

AOK-KA99052

Mathematical and Statistical Modelling in Medicine Lecture Mathematical and Statistical Modelling in Medicine Practice Chemical Misconceptions Criteria Subjects Hungarian Language IV.* Physical Education (P.E.)**

Form of exam

AOK-KA99051

Elective Subjects Clinical Anatomy Animal Experiments in Medicine

Department

Hrs/week: Practice

AOK-KUA241 AOK-KA99031

Course

-

3 -

Term Mark (5) Evaluation (5)

3 1

SR:AOK-KUA017

1

-

Evaluation (5)

2

-

Prof. Ferenc Bari

-

1

Signature

-

-

Prof. Gábor Tóth

2

-

Evaluation (5)

2

-

Dr. Éva Demeter

-

4 2

Prel.Exam Signature

-

SR:AOK-KUA253

Head of Department

Dept. of Anatomy Inst. of Surgical Research

Prof. András Mihály Prof. Mihály Boros

Dept. of Med. Physics and Informatics Dept. of Med. Physics and Informatics Dept. of Med. Chemistry

Prof. Ferenc Bari


* The completion of the course is obligatory in the semester given. ** One has to complete 2 semesters of Physical Education until the end of the 5th year.


Hrs/week: Theory

Course Code

43


total 22

-

-

44

Form of exam

Credit

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


1st Dept. of Int.Med. / 2nd Dept. of Int.Med. 1st Dept. of Int.Med. / 2nd Dept. of Int.Med. Dept. of Pathophysiology Dept. of Pathophysiology Dept. of Med. Microbiology Dept. of Med. Microbiology Dept. of Pathology Dept. of Pathology

Dr. György Ábrahám / Prof. Tamás Forster Dr. György Ábrahám / Prof. Tamás Forster Prof. Gyula Szabó Prof. Gyula Szabó Dr. Katalin Burián Dr. Katalin Burián Prof. Béla Iványi Prof. Béla Iványi

2

-

Examination

3

Basic Module

-

2

Signature

-

Basic Module

3 3 3 -

2 2 3

Examination Signature Examination Signature Examination Signature

5 5 6 -

Basic Basic Basic Basic Basic Basic

Inst. of Surgical Research Inst. of Surgical Research

Prof. Mihály Boros Prof. Mihály Boros

1 -

2

Evaluation(5) Signature

3 -

Inst. of Surgical Research

Prof. Mihály Boros

total: 8

-

Evaluation(5)

2

Signature

-

Basic Module Basic Module parallel completion of Basic Surg. Skills parallel completion of Basic Surg. Skills

Department

Head of Department

MEDICINE PRE-CLINICAL MODULE 2014/2015 3rd year, 5th (fall) semester AOK-KA711 AOK-KA712 AOK-KA731 AOK-KA732 AOK-KA741 AOK-KA742 AOK-KA781 AOK-KA782

Compulsory Subjects Clinical Diagnostics I. (Internal Medicine Basics of Haematology) Clinical Diagnostics I. (Internal Medicine)

AOK-KA1441 AOK-KA1442

Pathophysiology I. Pathophysiology I. Microbiology and Immunology I. Microbiology and Immunology I. Pathology I. Pathology I. Compulsory Elective Subjects Basic Surgical Skills Basic Surgical Skills

AOK-KA1451

Microsurgery

AOK-KA1452

Microsurgery

AOK-KA1011

Molecular Medicine

AOK-KA1611

Pathophysiology of Sepsis at the Bedside Elective Subjects Animal Experiments in Medicine

AOK-KA9903P AOK-KA1771P

Body Development and Diseases and a Molecular Biological Background

Module Module Module Module Module Module

Inst. of Surgical Research Dept. of Cell Biology and Molecular Medicine Dept. of Anesthesiology and Intensive Therapy

Prof. Mihály Boros

-

total: 20

Prof. Károly Gulya Prof. Zsolt Molnár

2

-

Evaluation(5)

2

Basic Module

1

-

Evaluation(5)

1

Basic Module

Inst. of Surgical Research Dept. of Biochemistry

Prof. Mihály Boros Prof. László Dux

total 22

-

Evaluation(5)

1

-

2

-

Evaluation(5)

2



Prof. Ferenc Bari

Dept. of Foreign Lang.

Dr. Éva Demeter

* The completion of the course is obligatory in the semester given.

Credit

Head of Department

Form of exam

AOK-KA4715

Cerebral Blood Flow and Metabolism Criteria Subjects Hungarian Language V.*

Department

Hrs/week: Practice

AOK-KA1027

Course

Hrs/week: Theory

Course Code

45 Course Requirement (SR=Subject requirement; ER=Examination requirement; P=Parallel Completion)

2

-

Evaluation(5)

2

Basic Module

-

3

Term Mark(5)

-

Basic Module

46


3 5

SR:Clin. Diagnos. I. SR:Clin. Diagnos. I. SR:Pathophysiology. I.

5

SR:Pathophysiology. I. SR: Microbiology I.

6

SR: Microbiology I. SR: Pathology I.

3 2 3 -

SR: Pathology I. Basic Module Basic Module Basic Module Basic Module Basic Module Basic Module

Signature

-

SR: Basic Surgical Skills

Term Mark(5) Evaluation(5) Signature Evaluation(5)

2 2 2

SR: Basic Surgical Skills SR: Basic Surgical Skills SR: Basic Surgical Skills -

Hrs/week: Theory

Hrs/week: Practice

Form of exam

Credit


AOK-KA721 AOK-KA722 AOK-KA733

Compulsory Subjects Internal Medicine I. Internal Medicine I. Pathophysiology II.

1st Dept. of Int.Med. 1st Dept. of Int.Med. Dept. of Pathophysiology

Dr. György Ábrahám Dr. György Ábrahám Prof. Gyula Szabó

3 3

2 -

AOK-KA734 AOK-KA743

Pathophysiology II. Microbiology and Immunology II.

Dept. of Pathophysiology Dept. of Med. Microbiology

Prof. Gyula Szabó Dr. Katalin Burián

3

2 -

AOK-KA744 AOK-KA783

Microbiology and Immunology II. Pathology II.

Dept. of Med. Microbiology Dept. of Pathology

Dr. Katalin Burián Prof. Béla Iványi

2

2 -


Pathology II. Clinical Diagnostics II. (Surgery) Clinical Diagnostics II. (Surgery) Medical Psychology I. Medical Psychology I. Ethics in Medicine Ethics in Medicine Compulsory Elective Subjects

Dept. of Pathology Dept. of Surgery Dept. of Surgery Dept.of Behavioural Dept.of Behavioural Dept.of Behavioural Dept.of Behavioural

Prof. Béla Iványi Prof. György Lázár Prof. György Lázár Dr. Katalin Barabás Dr. Katalin Barabás Dr. Katalin Barabás Dr. Katalin Barabás

2 1 1 -

4 2 1 2

Examination Signature Comprehensive Exam Signature Comprehensive Exam Signature Comprehensive Exam Signature Examination Signature Evaluation(5) Signature Examination Signature

AOK-KA1471

Basics of Emergency Medicine

Prof. Mihály Boros

1

-

AOK-KA1472 AOK-KA1461 AOK-KA1462 AOK-KA881P

Basics of Emergency Medicine Advanced Surgical Skills Advanced Surgical Skills Molecular Developmental-Biology


1 2

2 1 -

Course Code

Course

Department

Head of Department

Course Code

MEDICINE PRE-CLINICAL MODULE 2014/2015 3rd year, 6th (spring) semester

Sciences Sciences Sciences Sciences

Inst. of Surgical Research, Dep. of Anaesthesiology Inst. of Surgical Research, Dep. of Anaesthesiology Inst. of Surgical Research Inst. of Surgical Research Dept. of Biochemistry

Mihály Boros Mihály Boros Mihály Boros László Dux


Microsurgery

AOK-KA1452 AOK-KA831 AOK-KA671 AOK-KA672 AOK-KA1023 AOK-KA1711P AOKKA99031P AOK-KA99061 AOK-KA99062 AOK-KA911 AOK-KA4716 AOK-KA9811

Microsurgery Pathophysiological Aspects of Laboratory Medicine Gerontology Gerontology Elective Subjects Basic Immunpathology Biotechnology from a Business Perspective Animal Experiments in Medicine Mathematical and Statistical Modelling in Medicine Lecture Mathematical and Statistical Modelling in Medicine Practice Chemical Misconceptions Criteria Subjects Hungarian Language VI.* Internal Medicine Practice

Credit

AOK-KA1451

Form of exam

Microbiological Probems in Med. Practice

Hrs/week: Practice

AOK-KA821

Course

Hrs/week: Theory

Course Code


Dr. Katalin Burián

1

-

Evaluation(5)

1

Basic Module

Prof. Mihály Boros

total: 8

-

Evaluation(5)

2


-

total: 20

Signature

-


Dept. of Laboratory Medicine Dr.Földesi Imre Dept.of Behavioural Sciences Dr. Katalin Barabás Dept.of Behavioural Sciences Dr. Katalin Barabás

2 1 -

1

Evaluation(5) Evaluation(5) Signature

2 2 -

Basic Module Basic Module Basic Module

Inst. of Surgical Research Dept. of Biotechnology

1 2

-


1 2 1

SR: Microbiology I. Basic Module -

1

-

Evaluation(5)

2

-

Department

Dept. of Med. Microbiology Inst. of Surgical Research Inst. of Surgical Research

Head of Department

Prof. Mihály Boros

Prof. Mihály Boros Prof. Kornél Kovács L.

Inst. of Surgical Research Dept. of Med. Physics and Informatics Dept. of Med. Physics and Informatics Dept. of Med. Chemistry

Prof. Ferenc Bari

-

1

Signature

-

-

Prof. Gábor Tóth

2

-

Evaluation (5)

2

-

Dept. of Foreign Languages

Dr. Éva Demeter

-

3 4x30


-

SR: Hung. Lang. V.

* The completion of the course is obligatory in the semester given.

Prof. Mihály Boros Prof. Ferenc Bari

total 22

48

SUGGESTED STUDY PLAN Form of exam

Credit

Department

Examination Signature Examination Signature Examination Signature Examination Signature Examination Signature Evaluation(5) Signature Evaluation(5) Signature Examination Signature Signature

5 5 3 3 2 2 3 4 -

Prof. Zsuzsanna Kahán Dr. Katalin Nagy Dr. Katalin Nagy Dr. Katalin Barabás Dr. Katalin Barabás

5 2 3 2 2 2 2 2 1 2 1 1 2 2 3 2 total 3 days 2 1 2 1 1

Examination Examination Signature Evaluation(5) Signature

2 2 1 -

SR: Obstetrics I. Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module

Dr. Éva Demeter

-

Term Mark(5)

-

Pre-Clinical Module

Head of Department

Hrs/week: Practice

Course

Hrs/week: Theory

Course Code


MEDICINE CLINICAL MODULE 2014/2015 4th year, 7th (fall) semester AOK-KA201 AOK-KA202 AOK-KA231 AOK-KA232 AOK-KA271 AOK-KA272 AOK-KA291 AOK-KA292 AOK-KA311 AOK-KA312 AOK-KA321 AOK-KA322 AOK-KA331 AOK-KA332 AOK-KA351 AOK-KA352 AOK-KA353 AOK-KA381 AOK-KA651 AOK-KA652 AOK-KA961 AOK-KA962 AOK-KA4717

Compulsory Subjects Internal Medicine II. Internal Medicine II. Pharmacology Pharmacology Public Health I. Lecture Public Health I. Practice Orthopedics Orthopedics Pulmonology Pulmonology Radiology I. Radiology I. Surgery I. Surgery I. Obstetrics and Gynaecology I. Obstetrics and Gynaecology I. Delivery-Room** Clinical Oncology Stomatology Stomatology Medical Psychology II. Medical Psychology II. Criteria Subjects Hungarian Language VII.*

2nd Dept. of Int.Med. 2nd Dept. of Int.Med. Dept. of Pharmacology Dept. of Pharmacology Department of Public Health Department of Public Health Dept. of Orthopedics Dept. of Orthopedics Dept. of Pulmonolgy Dept. of Pulmonolgy Dept. of Radiology Dept. of Radiology Dept. of Surgery Dept. of Surgery Dept. of Obstetrics and G. Dept. of Obstetrics and G. Dept. of Obstetrics and G.

Prof. Tamás Forster Prof. Tamás Forster Prof. András Varró Prof. András Varró Dr. Edit Paulik Dr. Edit Paulik Prof. Kálmán Tóth Prof. Kálmán Tóth Prof. Attila Somfay Prof. Attila Somfay Prof. András Palkó Prof. András Palkó Prof. György Lázár Prof. György Lázár Prof. Attila Pál Prof. Attila Pál Prof. Attila Pál

Dept. of Oncology Dept. of Stomatology Dept. of Stomatology Dept.of Behavioural Sciences Dept.of Behavioural Sciences Dept. of Foreign Lang.

3

Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module SR: 6th semester SR: 6th semester Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module


Doctor-Patient Communication** Examination in Behavioural Sciences

Dept.of Behavioural Sciences Dr. Katalin Barabás Dept.of Behavioural Sciences Dr. Katalin Barabás

* The completion of the course is obligatory in the semester given. ** Only half of the 4th year students can register in each semester.

-

2 -

Signature Comprehensive Exam

Credit

Head of Department

Form of exam

Department

Hrs/week: Practice

AOK-KA681 AOK-KA591

Course

Hrs/week: Theory

Course Code

49

-

Course Requirement (SR=Subject requirement; ER=Examination requirement; P=Parallel Completion) Pre-Clinical Module

50

Compulsory Subjects Internal Medicine III. Internal Medicine III. Pharmacology II.

1st Dept. of Internal Med. 1st Dept. of Internal Med. Dept. of Pharmacology

Dr. György Ábrahám Dr. György Ábrahám Prof. András Varró

5 4

2 -

AOK-KA234 AOK-KA273 AOK-KA274 AOK-KA323 AOK-KA324 AOK-KA333 AOK-KA334 AOK-KA354 AOK-KA355 AOK-KA356

Pharmacology II. Public Health II. Lecture Public Health II. Practice Radiology II. Radiology II. Surgery II. Surgery II. Obstetrics and Gynaecology II. Obstetrics and Gynaecology II. Delivery-Room**

Dept. of Pharmacology Department of Public Health Department of Public Health Dept. of Radiology Dept. of Radiology Dept. of Surgery Dept. of Surgery Dept. of Obstetrics and G. Dept. of Obstetrics and G. Dept. of Obstetrics and G.

Prof. András Varró Dr. Edit Paulik Dr. Edit Paulik Prof. András Palkó Prof. András Palkó Prof. György Lázár Prof. György Lázár Prof. Attila Pál Prof. Attila Pál Prof. Attila Pál

2 2 2 1 1 2 2 3 2 total 3 days

Course

Department

Head of Department

Credit

Hrs/week: Practice


Course Code

Form of exam

Hrs/week: Theory


MEDICINE CLINICAL MODULE 2014/2015 4th year, 8th (spring) semester Examination Signature Comprehensive Exam Signature Examination Signature Examination Signature Examination Signature Evaluation(5) Signature Signature

5 5 3 2 3 4 -

SR: Internal Med. II. SR: Internal Med. II. SR: Pharmacology I. SR: Pharmacology I. SR: Public Health I. SR: Public Health I. SR: Radiology I. SR: Radiology I. SR: Surgery I. SR: Surgery I. SR: Obstetrics I. SR: Obstetrics I. SR: Obstetrics I.

Criteria Subjects AOK-KA4718 AOK-KA681 AOK-KA701

Hungarian Language VIII.* Doctor-Patient Communication** Surgery Summer Practice

Dept. of Foreign Lang. Dr. Éva Demeter Dept.of Behavioural Sciences Dr. Katalin Barabás

* The completion of the course is obligatory in the semester given. ** Only half of the 4th year students can register in each semester.

-

3 2 4x30

Comprehensive Exam Signature Signature

-

SR: Hungarian Language VII.


51

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


Prof. Zsolt Molnár

2

-

Evaluation(5)

1

Pre-Clinical Module

Prof. Zsolt Molnár

-

1

Signature

-

Pre-Clinical Module

Head of Department

MEDICINE CLINICAL MODULE 2014/2015 5th year, 9th (fall) semester Compulsory Subjects AOK-KA191

Anesthesiology and Intensive Therapy I.

AOK-KA192

Anesthesiology and Intensive Therapy I.

AOK-KA205 AOK-KA0211 AOK-KA335 AOK-KA336 AOK-KA251 AOK-KA252 AOK-KA281 AOK-KA282 AOK-KA301 AOK-KA302

Internal Medicine - Infectology Practice Internal Medicine - Infectology - Infectious Diseases Lecture Surgery III. Surgery III. Pediatrics I. Pediatrics I. Neurology I. Neurology I. Psychiatry I. Psychiatry I.

AOK-KA261

Forensic Medicine I.


Forensic Medicine I. Dermatology Dermatology

AOK-KA241

Oto-Rhino-Laryngology

AOK-KA242


Dept. of Anesthesiology and Intensive Therapy Dept. of Anesthesiology and Intensive Therapy 1st Dept. of Int.Med. / 2nd Dept. of Int.Med. 1st Dept. of Int.Med. / 2nd Dept. of Int.Med. Department of Surgery Department of Surgery Department of Pediatrics Department of Pediatrics Department of Neurology Department of Neurology Department of Psychiatry Department of Psychiatry Department of Forensic Medicine Department of Forensic Medicine Department of Dermatology Department of Dermatology Department of Oto-RhinoLaryngology Department of Oto-RhinoLaryngology

Dr. György Ábrahám / Prof. Tamás Forster Dr. György Ábrahám / Prof. Tamás Forster Prof. György Lázár Prof. György Lázár Dr. Csaba Berecki Dr. Csaba Berecki Prof. László Vécsei Prof. László Vécsei Prof. János Kálmán Prof. János Kálmán

-

2

Signature

0

SR: 8th semester

2 1 3 1 1 -

1 2 2 1

Examination Evaluation (5) Signature Examination Signature Examination Signature Signature Term Mark (5)

3 2 5 3 2

Dr. Éva Kereszty

1

-

Examination

3

Dr. Éva Kereszty Prof. Lajos Kemény Prof. Lajos Kemény

2 -

2 3

Signature Examination Signature

4 -

Dr. László Rovó

2

-

Examination

4

Dr. László Rovó

-

3

Signature

-

SR: 8th semester SR: Surgery II. SR: Surgery II. SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester SR: 8th semester

Head of Department

AOK-KA1201

Compulsory Elective Subjects in the Clinical Module, fall semester (semester 7 and 9) Dept. of Med. Physics and Informatics Basic Biostatistics Prof. Ferenc Bari Introduction to Aviation and Space Medicine Dept. of Aviation and Space Medicine Prof. Andor Grósz Dept. of Med. Physics and Medical Informatics I. Informatics Prof. Ferenc Bari Medical Molecular Biology and Genomics Dept. of Med. Biology Prof. Zsolt Boldogkıi Microsurgery Inst. of Surgical Research Prof. Mihály Boros Microsurgery Inst. of Surgical Research Prof. Mihály Boros Nuclear Medicine Dept. of Nuclear Med. Prof. László Pávics Pharmacology Cases I. Dept. of Pharmacology Prof. András Varró The Language of Effective Doctor-Patient Communication Dept. of Foreign Lang. Dr. Éva Demeter Compulsory Elective Subjects in the Clinical Module, only semester 9 Rheumatology Dept. of Rheumatology Dr. László Kovács Elective Subjects in the Clinical Module, only semester 9 Biophysics of Hearing. Objective and Subjective Department of Oto-RhinoAudiometry Laryngology Dr. László Rovó Diseases of the Temporomandibular System Department of Prosthodontics and Oral Biology Dr. Márta Radnai Diseases of the Temporomandibular System Department of Prosthodontics and Oral Biology Dr. Márta Radnai Elective Subjects in the Clinical Module, fall semester (semester 7 and 9) Sexual Disorders - Gynecological Aspects Dept. of Obstetrics and G. Prof. Attila Pál Tropical Medicine Department of Psychiatry Prof. János Kálmán Modern Approach of the Gynecological Laparoscopy Dept. of Obstetrics and G. Prof. Attila Pál

AOK-KA9903K

Animal Experiments in Medicine

AOK-KA1881

Esthetics of the Face

AOK-KA1841

Medical History Taking in Hungarian


AOK-KA451 AOK-KA1791 AOK-KA1451K AOK-KA1452K AOK-KA421 AOK-KA1061 AOK-KA1581

AOK-KA531



Inst. of Surgical Research Dept. Of Operative and Esthetic Dentistry Dept. Of Foreign Lang.

Prof. Mihály Boros Prof. Katalin Nagy Dr. Éva Demeter

2

-

Evaluation(5)

2

-

Evaluation(5)

2 1 total 8

-


1 -

total 20 2

Signature Evaluation(5) Term Mark(5)

-

2

Term Mark(5)

2

-

1 1

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

52 Course Requirement (SR=Subject requirement; ER=Examination requirement; P=Parallel Completion) Pre-Clinical Module 2 2

Pre-Clinical Module Pre-Clinical Module

2 1 2

Pre-Clinical Module SR: Basic Surgical Skills

1 2 2

SR: Basic Surgical Skills Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module

Evaluation(5)

2

SR: 8th semester

-


1 2

SR: 8th semester

-

1

Signature

-

SR: 8th semester

1 2

-


1 2

Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module

1 total 22 1

-


1 1

-

-

Examination

1

Pre-Clinical Module

-

2

Term Mark(5)

2

Pre-Clinical Module

SR: 8th semester


53

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


Prof. Zsolt Molnár

2

-

Examination

2

Prof. Zsolt Molnár

-

1

Signature

-

Head of Department


MEDICINE CLINICAL MODULE 2014/2015 5th year, 10th (spring) semester AOK-KA193

Compulsory Subjects Anesthesiology and Intensive Therapy II.

AOK-KA194

Anesthesiology and Intensive Therapy II.

AOK-KA207

Internal Medicine V.


Internal Medicine V. Pediatrics II. Pediatrics II. Neurology II. Neurology II. Psychiatry II. Psychiatry II.

AOK-KA263

Forensic Medicine II.


Forensic Medicine II. Ophthalmology Ophthalmology Urology Urology Traumatology Traumatology

Dept. of Anesthesiology and Intensive Therapy Dept. of Anesthesiology and Intensive Therapy 1st Dept. of Int.Med. / 2nd Dept. of Int.Med. 1st Dept. of Int.Med. / 2nd Dept. of Int.Med. Department of Pediatrics Department of Pediatrics Department of Neurology Department of Neurology Department of Psychiatry Department of Psychiatry Department of Forensic Medicine Department of Forensic Medicine Department of Ophthalmology Department of Ophthalmology Department of Urology Department of Urology Department of Traumatology Department of Traumatology

SR: Anesthesiology I. SR: Anesthesiology I. Dr. György Ábrahám / Prof. Tamás Forster Dr. György Ábrahám / Prof. Tamás Forster Dr. Csaba Berecki Dr. Csaba Berecki Prof. László Vécsei Prof. László Vécsei Prof. János Kálmán Prof. János Kálmán

2

Examination

3

SR: 9th sem.

2 1 2 -

total 16 2 1 1

Signature Evaluation (5) Signature Evaluation(5) Signature Examination S

4 2 3 -

SR: 9th sem. SR: Pediatrics I. SR: Pediatrics I. SR: Neurology I. SR: Neurology I. SR: Psychiatry I. SR: Psychiatry I.

Dr. Éva Kereszty

1

-

Examination

3

SR: Forensic Medicine I.

Dr. Éva Kereszty Prof. Andrea Facskó Prof. Andrea Facskó Dr. Olivér Pintér Dr. Olivér Pintér Prof. Aurél J. Simonka Prof. Aurél J. Simonka

2 1 2 -

2 2 2 2

Signature Examination Signature Examination Signature Examination Signature

3 2 3 -

SR: Forensic Medicine I. SR: 9th sem. SR: 9th sem. SR: 9th sem. SR: 9th sem. SR: 9th sem. SR: 9th sem.

AOK-KA691 AOK-KASZD101

AOK-KA4321 AOK-KA1461 AOK-KA1462 AOK-KA1731K AOK-KA481 AOK-KA861K AOK-KA862K

AOK-KA211 AOK-KA491 AOK-KA501 AOK-KA1451K AOK-KA1452K AOK-KA881K AOK-KA1511 AOK-KA1521

Head of Department

Compulsory Elective Subjects in the Clinical Module, only semester 10 Neurosurgery Department of Neurosurgery Prof. Pál Barzó Neurosurgery Department of Neurosurgery Prof. Pál Barzó Department of Medical Genetics Clinical Genetics and Genomics Dr. Széll Márta Criteria Subjects Examination of Forensic Medicine-Public Dept of Forensic Medicine / Dr. Éva Kereszty / Dr. Health Dept. Of Puplic Health Edit Paulik Thesis Consultation Compulsory Elective Subjects in the Clinical Module, spring semester (semester 8 and 10) Dept. of Med. Physics and Advanced Biostatistics Informatics Prof. Ferenc Bari Advanced Surgical Skills Inst. of Surgical Research Prof. Mihály Boros Advanced Surgical Skills Inst. of Surgical Research Prof. Mihály Boros Dept. of Anesthesiology and Applied Cardiorespiratory Pathophysiology Intensive Therapy Prof. Zsolt Molnár Cases in Medical Microbiology and Infectious Department of Clinical Dr. habil Edit Urbán Diseases Microbiology Cardiac Electrophysiology as a Basic Dept. of Pharmacology Prof. András Varró Property of Cardiac Function Cardiac Electrophysiology as a Basic Dept. of Pharmacology Prof. András Varró Property of Cardiac Function Child and Adolescent Psychiatry, Dept. Of Child and Mentalhygiene Adolescent Psychiatry Dr. Ágnes Vetró Clinical Immunology Dept. of Dermatology Prof. Lajos Kemény Laboratory Diagnostics in Clinical Practice Dept. of Laboratory Medicine Dr. Földesi Imre Microsurgery Inst. of Surgical Research Prof. Mihály Boros Microsurgery Inst. of Surgical Research Prof. Mihály Boros Molecular Developmental-Biology Dept. of Biochemistry Prof. László Dux Oral and Maxillofacial Surgery Maxillofacial Surgery Clinic Prof. József Piffkó Oral and Maxillofacial Surgery Maxillofacial Surgery Clinic Prof. József Piffkó

Credit

AOK-KA411

Department

Form of exam

AOK-KA401 AOK-KA402

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


1 -

1

Examination Signature

2 -

SR: 9th sem. SR: 9th sem.

2

-

Evaluation(5)

2

SR: 9th sem.

-

-

-

total 30

2 1 -

Comprehensive Exam Signature

-

1

Evaluation(5) Evaluation(5) Signature

2 2 -

SR: Basic Biostatistics SR: Basic Surgical Skills SR: Basic Surgical Skills

1

-

Evaluation(5)

1

Pre-Clinical Module

2 1

-


2 2


-

1

Signature

-

-

2 2 2

-


Pre-Clinical Module Pre-Clinical Module SR: 9th sem.

-

Evaluation(5)

2 2 2 2

total 8

2 1 -

total 20

1

Signature Evaluation(5) Evaluation(5) Signature

-

2 2 -

SR: Basic Surgical Skills SR: Basic Surgical Skills Pre-Clinical Module Pre-Clinical Module


AOK-KA1582

AOK-KA1211

AOK-KA1331 AOK-KA1851 AOK-KA1861 AOK-KA911K AOK-KA1831 AOK-KA1841

Dept. of Pharmacology Dept. of Public Health Dept. of Aviation and Space Medicine

Dept. of Foreign Lang. Department of Clinical Microbiology Elective Subjects in the Clinical Module, spring semester (semester Multidisciplinary care of breast cancer Dept. of Oncology Dept. of Oncology Modern Complex Therapy of Malignant Diseases Dept. of Oncology Intensive Course on Radiation Oncology Chemical Misconceptions Dept. of Med. Chemistry Illicite Drug Use Dept. Of Psychiatry Medical History Taking in Hungarian Dept. Of Foreign Lang. Tropical Diseases

Prof. András Varró Dr. Edit Paulik

2

2 -


Prof. Andor Grósz

2

-

Evaluation(5)

Head of Department

Credit

Form of exam

Pharmacology Cases II. Social and Health Policy The Clinical Basics of Aviation and Space Medicine The Language of Effective Doctor-Patient Communication II.

Department

Hrs/week: Practice


Course

Hrs/week: Theory

Course Code

55

2 2 2

2

2

Term Mark(5)

-

2 1 2 2 -

2 2

The Language of Effective DoctorPatient Communication I.

2 Evaluation(5)

8 and 10) Prof. Zsuzsanna Kahán Prof. Zsuzsanna Kahán Prof. Zsuzsanna Kahán Prof. Gábor Tóth Prof. János Kálmán Dr. Éva Demeter

SR: Pharmacology Cases I. Pre-Clinical Module Pre-Clinical Module

2

Dr. Éva Demeter Dr. habil Edit Urbán


Evaluation(5) Term mark(5) Evaluation (5) Evaluation (5) Evaluation(5) Term Mark(5)

Pre-Clinical Module

2 2 1 2 2 2

Pre-Clinical Module Pre-Clinical Module Pre-Clinical Module


56

Head of Department

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


9

Clinical Module

9

Clinical Module Clinical Module

5

Clinical Module

5

Clinical Module

4

Clinical Module

8

Clinical Module

20

Clinical Module Clinical Module

MEDICINE FINAL MODULE 2014/2015 6th year AOK-KA901 AOK-KA902 AOK-KA941 AOK-KA921 AOK-KA931 AOK-KA951 AOK-KA911

Compulsory Subjects Internal Medicine

1st Department of Internal Medicine

Dr. György Ábrahám 9 weeks* 1 week*

General Practice Surgery

Department of Surgery

Prof. György Lázár

Neurology

Department of Neurology

Prof. László Vécsei

9 weeks* 4 weeks* Psychiatry

Department of Psychiatry

Prof. János Kálmán 4 weeks*

Obstetrics and Gynaecology Pediatrics

Department of Obstetrics and Gynaecology Department of Pediatrics

Prof. Attila Pál 5 weeks* Dr. Csaba Berecki

AOK-KA912 AOK-KA971 AOK-KA972 AOK-KA973 AOK-KA974

District Pediatric Consultation Thesis State Board Examination - written part State Board Examination - oral part State Board Examination - practical part *1 week = 30 hours

7 weeks* 1 week* -

Comprehensive Exam Signature Comprehensive Exam Comprehensive Exam Comprehensive Exam Comprehensive Exam Comprehensive Exam Signature Defence Examination Examination Examination


57 6 th year (11th and 12th semester) academic year 2013/2014

The internships should be accomplished principally at the clinics and hospitals of the University, however they can be also accomplished abroad, provided the students submit the acceptance letter of the clinic/hospital and have the permission of the Department concerned before starting the practice. The accomplishment of the practices must be verified officially to the Secretariat as the precondition for starting the next practice. Two practices can be accomplished continuously and the final examinations can be taken in the week following the accomplishment of the practices. In the sixth year interns can be assigned to duty service as physicians. If the student fails an examination, it must be repeated together with the half of the practice period. The next practice can be started only following a successful examination. If the student fails to submit the thesis by the deadline given - or fails to submit it by the deadline of postponement (permission for postponement is given by the Program Director), his/her internships and examinations must be suspended. The State Board Examination consists of: Test (Multiple Choice Questions), Oral examination (theory) and Practical examination (bedside examination).

Fees:

Sixth year practices Period of practice

Fee

•

Obligatory fee *

6,250 USD

•

All practices are spent at the University of Szeged (40 weeks)

12,500 USD

•

1 extra week of practice at the University of Szeged

290 USD

•

1 extra month of practice at the University of Szeged

1160 USD

State Board Examination fee

300 USD

* Students can complete half of the practices abroad. This amount entitles them to complete half of the practices (20 weeks) at the University of Szeged without additional costs. ** Students can complete more than half of the practices abroad, provided they have the permission of the Program Director before starting the practice. Payments have to be made before starting the practice, but latest before the final examination of the subject concerned.

Further details are available in the relevant Clerkship Guide.

58

COMPULSORY PRACTICES IN SUMMER Summer practice: 1st, 3rd and 4th year students are required to complete a four-week compulsory summer practice in a hospital or clinic which must be accredited by the country concerned. At the completion of the practice an “Evaluation form” should be filled in, signed, stamped and sent directly from the hospital/clinic or submitted by the student in a sealed envelope. (The form can be downloaded from our website). A “Letter of Acceptance” issued by the hospital/clinic, furthermore a certificate that the hospital/clinic is accredited by the country concerned has to be presented at the Foreign Students’ Secretariat until May 06, 2014.

Fees if the practices are performed in Hungary: • Nursing practice: 500 USD • Internal Medicine practice: 1000 USD • Surgery practice: 1000 USD. Students should register for completing a practice at least one month before its beginning. Practice fee must be paid before starting the practice. 1st year medical students have to perform a four-week Nursing practice. Departments at the University of Szeged: 1st Department of Internal Medicine 2nd Department of Internal Medicine Obstetrics and Gynecology Department Department of Surgery Neurosurgery Department Neurology Department Psychiatry Department Pediatrics Department Ophthalmology Department Oto-Rhino-Laryngology and Head-Neck Surgery Department Urology Department Pulmonology Department Traumatology Department

3rd year medical students have to perform a four-week Internal Medicine practice. Departments at the University of Szeged: 1st Department of Internal Medicine Division of Endocrinology 2nd Department of Internal Medicine

4th year medical students have to perform a four-week Surgery practice. Departments at the University of Szeged: Department of Surgery

INTERIM PRACTICE

4th year medical students have to complete a three-day Obstetrics and Gynaecology Delivery-Room Practice in one semester.


59 EXTRACURRICULAR SCIENTIFIC ACTIVITY

Department of Anatomy, Histology and Embryology Department 1. Gene expression in the mammalian central nervous system. Prof. Dr. Andras Mihaly 2. Role of animal experiments in research of diseases of the central nervous system Dr. Endre Dobo, PhD Department of Nuclear Medicine 1. Up to date Nuclear Medicine investigations in neurology and psichiatry Dr. László Pávics Professor of Nuclear Medicine 2. Experimental validation of new radiopharmaneuticals Dr. László Pávics Professor of Nuclear Medicine 3. Radiation safety in Nuclear Medicine Dr. Teréz Séra physicist 4. New Nuclear Medicine investigations in oncology Dr. Miklós Papós associate professor Department of Clinical Microbiology 1. Specially selected topics dealing with sexually transmitted infections. Dr. habil Judit Deák 2. Specially selected topics dealing with tropical diseases. Diagnostic problems, epidemiology, and therapy. Dr. habil Judit Deák 3. Antibiotic resistance development in a selected pathogen. Dr. habil. DSc. Elisabeth Nagy 4. Anaerobic infections. Diagnostics and therapy. Dr. Edit Urbán Ph.D. 5. Role of anaerobic bacteria in oral infections. Dr. Edit Urbán Ph.D. 6. Clostridium difficile-associated infections. Dr. Gabriella Terhes Ph.D.

60 Department of Otolaryngology and Head & Neck Surgery 1. Pathogenesis and treatment of laryngeal tumors 2. Pathophysiology and treatment of vocal cord functional disorders Department of Behavioural Sciences 1. Behavioral science approach to smoking Dr. Bettina Pikó associate professor 2. Cultural medicine: theory and examples Dr. Bettina Pikó associate professor 3. Prevention of addictions Dr. Bettina Pikó associate professor 4. Stress and anxiety in modern medicine Dr. Bettina Pikó associate professor Department of Otolaryngology and Head & Neck Surgery Biophysics of hearing. Objective and subjective audiometry Dr. Kiss József Géza Surgical treatment for laryngeal carcinoma and quality of life (QOL) 1st semester, years 4-5 Prof. Czigner Jenı Department of Forensic Medicine 1. Illegal drug use Dr. Antia Reka Tóth 2. Laboratory investigation of drug abuse Dr. László Institoris 3. The role of alcohol in traffic Prof. Tibor Varga 4. Forensci point of DNA investigations Dr. Bernadett Csányi 5. Evaluation of permanent disability Dr. Beáta Havasi 6. Problems of the health legislation Dr. Éva Kereszty 7. Death detection in the clinical practice Dr. Éva Kereszty 2nd Department of Internal Medicine Prognostic factors in multiple myeloma Szabolcs Modok, MD, PhD Pharmacologic and interventional treatment of atrial fibrillation Dr. Róbert Pap


61

Atrial flutter after open heart surgery Dr. Attila Makai Long-term efficacy of slow pathway ablation for atrioventricular nodal reentrant tachycardia Dr. László Sághy Heart failure and pacemaker therapy Dr. Gábor Bencsik 1st Department of Medicine Dr. Péter Hegyi and Dr. Zoltán Rakonczay 1. The regulation of pancreatic ductal HCO3- secretion. 2 2. The role of pancreatic ducts in the process of acute pancreatitis. 3. Acid secretion from human gastric glands. 4. The regulation of human intestinal ion secretion. 5. Characterisation of lacrimal gland epithelial cells. 6. Viral transfection of epithelial cells. Department of Pharmacology and Pharmacotherapy 1/ The mechanisms of action of antiarrhythmic drugs. Tutor: Dr. András Varró 2/ Cellular electrophysiology of the cardiac muscle. Tutor: Dr. András Varró 3/ Mechanism of the antiarrhythmic effect of preconditioning. Role of endogenous substances. Tutor: Dr. Ágnes Végh 4/ Investigation of antiarrhythmic mechanism in rat models. Tutor: Dr. István Leprán 5/ Potassium channel and cyclic nucleotide mediated vasodilation in isolated blood vessels. Tutor: Dr. János Pataricza 6/ Cellular electrophysiological techniques. Tutor: Dr. László Virág and Dr. Norbert Iost 7/ Patomechanisms of congestive heart failure Tutor: Dr. István Baczkó 8/ Intra-and extracellular regulatory mechanisms of electric activity in human cardiac atrium. Etiology and pathomechanism of atrial fibrillation. Tutor: Dr. Ottó Hála 9/ Regulation of the Ca2+ homeostasis in isolated cardiac cells. Tutor: Dr. András Tóth 10/ Cellular mechanism leading to ischemia/ reperfusion in jury in cardiac tissue. Tutor: Dr. András Tóth 11/ Review of the literature: A selected topic in pharmacology. Tutor: Dr. István Leprán Department of Medical Informatics 1. Oscillation mechanics of the human respiratory system Prof. Zoltán Hantos 2. Computer analysis of lung sounds

62 Prof. Zoltán Hantos 3. Studies on regulation of cerebral blood flow Prof. Ferenc Bari 4. Experimental models for cortical spreading depression Dr. Eszter Fazekas 5. Computer aided modelling in Pharmacy and Medicine Dr. János Karsai 6. Investigation of the role of enviromental factors in aetiology of childhood cancers Dr. Tibor Nyári 7. Investigation of the role of human papilloma virus in cervical carcinoma Dr. Tibor Nyári 8. Application of biostatistical methods to medical data Dr. Krisztina Boda Institute of Surgical Research 1. Pathomechanism of small bowel ischemia-reperfusion. Monitoring of microcirculatory changes with intravital videomicroscopy and OPS technique Prof. Mihály Boros, M.D., Ph.D., D.Sc. 2. Biological activity of phospholipids in inflammatory diseases Prof. Mihály Boros, M.D., Ph.D., D.Sc. 3. Protective effects of biological gases in circulatory disorders Prof. Mihály Boros, M.D., Ph.D., D.Sc. Dr. József Kaszaki, Ph.D. 4. Neuroprotection in the enteral nervous system Dr. József Kaszaki, Ph.D. 5. Examination of microcirculation under septic conditions Dr. József Kaszaki, Ph.D. 6. Assessment of hemodynamic and biochemical consequences of experimental pericardial tamponade Dr. József Kaszaki, Ph.D. 7. Examination of macro- and microhemodynamic consequences of volume therapy in circulatory shock Dr. József Kaszaki, Ph.D. 8. Examination of mechanical parameters of the lung under normal and pathologic conditions Dr. József Kaszaki, Ph.D. Prof. Zoltán Hantos, Ph.D., D.Sc., Department of Medical Physics and Informatics 9. Assessment of biochemical and microcirculatory consequences of disorders of the locomotor system using intravital videomicroscopy and OPS technique Dr. Andrea Szabó, M.D., Ph.D. 10. Assessment and treatment of biochemical and microcirculatory consequences of urogenital diseases Dr. Andrea Szabó, M.D., Ph.D. 11. Assessment and treatment of the oral surgical complications of chronic bisphosphonate

Curriculum 2014/2015 exposure Dr. Andrea Szabó, M.D., Ph.D. Department of Pathophysiology Student research program consultant: Dr Miklós Jászberényi, MD, PhD telephone number: 62-545-993 E-mail: [email protected], [email protected] Programs: 1. Tutors: Professor Dr Gyula Szabó, MD, PhD, DSc head of the department Topics: 1. Computer based education of pathophysiology (usage of internet in medical education) 2. The investigation of specific opiate ligands in animal experiments 3. Elected subject from pathophysiology 2. Tutors: Professor Dr Gyula Szabó, MD, PhD, DSc head of the department Julianna Szakács, MD Topics: 1. The effect of neuropeptides on experimental drug tolerance and dependence 2. Elective subject from pathophysiology 3. Tutors: Professor emeritus Gyula Telegdy, MD, PhD, DSc, member of the Hungarian Academy of Sciences Ágnes Adamik, MSc; Tanaka Masaru MD, PhD Topics: 1. The effects of neuropeptides on behavioral and cognitive processes 2. Examination of behavioral and cognitive processes in the rat 3. The effects of neuropeptides on thermoregulatory processes 4. The role of neuropeptides in the organization of cognitive processes 4. Tutor: Professor emeritus Gyula Telegdy, MD, PhD, DSc, member of the Hungarian Academy of Sciences Topics: 1. The role of nitric oxide in the organization of cognitive processes 2. The investigation of the anxiogenetic-anxiolytic effects of neuropeptides

5. Tutors: Professor Dr Gyula Szabó, MD, PhD, DSc head of the department Zsófia Mezei, MD, PhD Topics: 1. Role of the mediators in the pathogenesis of the cardiovascular diseases. 2. Role of the mediators in the pathogenesis of the neurodegenerative disorders. 3. Role of the mediators in the pathogenesis of the diabetes mellitus. 6. Tutors Professor emeritus Gyula Telegdy, MD, PhD, DSc, member of the Hungarian Academy of Sciences Professor Gyula Szabó, MD, PhD, DSc head of the department Miklós Jászberényi, MD, PhD Zsolt Bagosi, MD, PhD Krisztina Anna Csabafi, MD Topics: 1. The effects of neuropeptides on the hypothalamic-pituitary-adrenal axis 2. The investigation of anxiolytic and antidepressant effects of neuropeptides 3. The investigation of the thermoregulatory, cardiac and behavioral effects of neuropeptides 4. The interaction between neuropeptides and addictive drugs 5. The interaction between neuropeptides and neurotransmitters 6. The action of neuropeptides in the development of Alzheimer’s disease 7. The action of neuropeptides in different animal models of psychiatric disorders

63

64 Recommended textbooks for first year medical students It is recommended to purchase the latest edition of the following textbooks! ANATOMY, HISTOLOGY AND EMBRYOLOGY Obligatory: • Junqueira, Carneiro, Kelley: Basic Histology, Prentice Hall, International Student Edition, Mc Graw-Hill • Sadler: Langman's Medical Embryology, with Simbryo CD, Lippincott Williams & Wilkins • Kiernan: Barr’s The Human Nervous System, International Student Edition, Lippincott Williams & Wilkins • Snell, Richard S.: Clinical Anatomy, Lippincott Williams & Wilkins • Sobotta Atlas of Human Anatomy, Volume 1, (Latin Edition), Lippincott Williams & Wilkins • Sobotta Atlas of Human Anatomy, Volume 2, (Latin Edition), English Text with Latin Nomenclature, Lippincott Williams & Wilkins Recommended: • Drake, RL, Wayne Vogl, A, Mitchell, AWM.: Gray’s Anatomy for Students. Churchill Livingstone Elsevier, 2010. • Gartner, LP, Hiatt, JL: Concise Histology, Saunders Elsevier, 2011 • Moore, KL, Persaud, TVN, Torchia, MG.: Before we are Born. Essentials of Embryology and Birth Defects. Elservier Saunders, 2013 CELL BIOLOGY AND MOLECULAR GENETICS • William K. Purves, Gordon H. Orians: Life: The Science of Biology,W.H. Freeman and Company, New York • J. Darnell H. Lodish D. Baltimore: Molecular Cell Biology, W.H. Freeman and Company, New York • B. Alberts, D.B.J. Lewis, M. Raff. K. Roberts, J.D. Watson: Molecular Biology of the Cell, Garland Publishing, Inc. New York FIRST AID • Brent, Karren: First Aid for Colleges and Universities, Brady Morton Series INTRODUCTION TO MEDICINE • W. Bynum: The History of Medicine: A Very Short Introduction, Oxford, University Press • Bettina Pikó : Introduction to Medicine. Basic Principles of Behavioral Sciences and, Preventive Medicine. University of Szeged INTRODUCTION TO PSYCHOLOGY, BASICS OF NURSING • Atkinson and Hilgard: Introduction to psychology. Andover, Wadsworth Cengage Learning, 2009

MEDICAL CHEMISTRY Obligatory: • Ebbing-Hart: General Chemistry /Organic Chemistry, Houghton Mifflin Company Recommended: • Harold Hart: Organic Chemistry (A Short Course), Houghton Mifflin Company, Boston • P. Gergely: Organic and Bioorganic Chemistry for Medical Students, University Medical School of Debrecen, • John McMurry: Fundamentals of Organic Chemistry, Brooks/Cole Publishing Company, ITP, An International Thomson Publishing Company MEDICAL PHYSICS AND STATISTICS • Damjanovich-Fidy-Szöllısi (eds): Medical Biophysics. Medicina, 2009. • M.J. Campbell, D. Machin: Medical Statistics. A Commonsense Approach. John Wiley & Sons Chichester-New York- Brisbane-Toronto-Singapore , 1993. • Rice Virtual Lab in Statistics http://onlinestatbook.com/rvls.html

MEDICAL DICTIONARIES • Mosbey's: Mosbey's Medical, Nursing and Allied Health, Mosbey • Stedmans: Medical Dictionary, Williams and Wilkins


65

Recommended textbooks for second year medical students ANATOMY, HISTOLOGY AND EMBRYOLOGY Obligatory: • Junqueira, Carneiro, Kelley: Basic Histology, Prentice Hall, International Student Edition, Mc Graw-Hill • Sadler: Langman's Medical Embryology, with Simbryo CD, Lippincott Williams & Wilkins • Kiernan: Barr’s The Human Nervous System, International Student Edition, Lippincott Williams & • Snell, Richard S.: Clinical Anatomy, Lippincott Williams & Wilkins • Sobotta Atlas of Human Anatomy, Volume 1, (Latin Edition), Lippincott Williams & Wilkins • Sobotta Atlas of Human Anatomy, Volume 2, (Latin Edition), English Text with Latin Nomenclature, Lippincott Williams & Wilkins Recommended: • Kyung Won Chung: Gross Anatomy, Lippincott Williams & Wilkins • Netter, Frank H.: Atlas of Human Anatomy, Icon Learning Systems • Wolf, Heidegger: Wolf-Heidegger’s Atlas of Human Anatomy, Karger • Sobotta Atlas of Human Anatomy, Volume 1 (Head, Neck, Upper Limb), English Text with English Nomenclature, Lippincott Williams & Wilkins • Sobotta Atlas of Human Anatomy, Volume 2 (Trunk, Viscera, Lower Limb), English Text with English Nomenclature, Lippincott Williams & Wilkins • Sobotta Atlas of Human Anatomy, 2 Volume Set, English Text with English Nomenclature, Lippincott Williams & Wilkins • Tömböl Teréz: Topographic Anatomy, Medicina Könyvkiadó Rt. • B. Alberts, A. Johnson, J Lewis, M Raff, K. Roberts, P Walter: Molecular biology of the cell (4th ed. Garland Science) BIOCHEMISTRY, BIOCHEMISTRY SEMINAR Obligatory: • Robert K.Murray, Daryl K. Ganner, Peter A. Mayers, Vicot W. Rodwell: Harper’s Illustrated Biochemistry 29th Edition 2012 ISBN: 978-0-07-176576-3 Recommended for 1st semester: • W. J. Marshall, S. K. Bangert Clinical Chemistry 6th Edition 2008 ISBN:9780723434559 •

P.C. Champe, R. A. Harvey Lippincott’s Illustrated Reviews Biochemistry 4th Edition 2008 ISBN-13: 978-07817-6960-0

•

J.W. Baynes, M. H. Dominiczak Medical Biochemsitry 4th Edition, 2014-06-04 ISBN: 978-1-4557-4580-7

BIOCHEMICAL BASICS OF PREVENTIVE MEDICINE • Janet Christian and Janet Greger: Nutrition for Living, Addison-Wesley CARDIAC ELECTROPHYSIOLOGY AS A BASIC PROPERTY OF CARDIAC FUNCTION • Macfarlane PW, van Oosterom A, Janse MJ, Camm J, Kligfield P, Pahlm O, eds. Comprehensive Electrocardiology, 2nd Ed. Springer, London MATHEMATICAL AND STATISTICAL MODELLING IN MEDICINE • Mark Woodward: Epidemiology –Study design and Data analysis, Chapman & Hall/CRC 1999 • Interesting mathematical problems in every-day life. Electronic handout in Teaching Mathematics and Statistics in Sciences HU-SRB/0901/221/088 MEDICAL ANTHROPOLOGY • C.G.Helman: Culture, Health and Illness, Oxford University Press

66 MEDICAL PHYSIOLOGY • Arthur C.Guyton, John E. Hall: Textbook of Medical Physiology, Elsevier Science • Kim Barrett, Heddwen Brooks, Scott Biotano, Susan Barman: Ganong’s Review of Medical Physiology, McGraw Hill Publishers • Walter F. Boron, Emile L. Boulpaep: Medical Physiology, Saunders Elsevier • William F. Ganong: Review of Medical Physiology by The McGraw-Hill Companies Inc. • Fonyó Attila: Principles of Medical Physiology, Medicina Kiadó Zrt. • Albert Szent-Györgyi Medical University, Department of Physiology, Physiology Laboratory Manual, (handout) MEDICAL SOCIOLOGY • A. Giddens: Sociology 2009. Cambridge, Polity Press UK


67

Recommended textbooks for third year medical students HUNGARIAN LANGUAGE • GYİRFFY, Mária: Mi a panasz? Idióma Bt. Pécs, 1999, ISBN 963 04 8860 4 INTERNAL MEDICINE (CLINICAL DIAGNOSTICS) Obligatory: • Barbara Bates’: A Guide to Physical Examination and History Taking, 8th ed. with bonus CD, Lippincott Williams & Wilkins, ISBN: 078175819X or • Bates' Guide to Physical Examination and History Taking, Authors: Lynn S. Bickley, M.D. , Barbara Bates, Peter G. Szilagyi, Peter Gabor Szilagyi, Publication Date: December 2005., ISBN: 0781767180 Recommended: • Harrison's Principles of Internal Medicine, Authors: Kasper, Dennis L. Braunwald, Eugene Fauci, Anthony Hauser, Stephen Longo, Dan Jameson, J. Larry, ISBN: 0071391401, Publication Date: 2004-07-27, Edition:16 • Te-Chuan Chou: Chou’s Electrocardiography Clinical Practice, 5th ed., W.B. Saunders, 2001., ISBN: 0721686974 • Brostoff: Clinical Immunology – An Illustrated Outline, Mosby, 1994, ISBN: 1563756641 • Kumar, Parveen, Clark, Michael: Clinical Medicine, 5th ed., W. B. Saunders, 2002, ISBN: 0702025798 • Current Medical Diagnosis and Treatment 2006, Author(s): Lawrence M. Tierney, Jr., MD; Stephen J. McPhee, MD; Maxine A. Papadakis, MD, ISBN: 0071454101, Publication date: 2005, Edition 45th • Stone: Current Emergency Diagnosis & Treatment, 5th ed., Appleton & Lange, 2004., ISBN: 0071219757 MEDICAL MICROBIOLOGY AND IMMUNOLOGY • ABBAS et al., Cellular and Molecular Immunology, Sanders, Elsevier, 6th ed., 2007. • Greenwood at al., Medical Microbiology; Churchill, Livingstone, Elsevier; 17th ed., 2007. • Murphy et al., Janeway’s Immunology, Garland Science; 7th ed., 2008. • Murray et al., Medical Microbiology, Elsevier, Mosby 6th ed. 2009. • Practical Notes (Edited by R. Pusztai, University of Szeged, 2002) MICROSURGERY • Szabó, A., Vass, G., Zádor, Z., Boros, M.: Basics of Microsurgery. Manual for Medical Students, Szeged, 2004. (handout) PATHOLOGY • Kumar, Abbas, Aster: Robbins Basic Pathology, 9th Edition. W.B. Saunders Company Philadelphia, 2012. ISBN: 9781437717815 PATHOPHYSIOLOGY Texbooks • Gayton and Hall: Texbook of Medical Physiology 12th ed. 2011 ISBN: 978-1-4160-4574-8/978-0-8089-2400-5 • Damjanov: Pathophysiology, Elsevier (Saunders title), 2008, ISBN: 978-1-4160-0229-1 • McPhee, Hammer: Pathophysiology of Disease 6th ed., McGraw-Hill Medical, 2009, ISBN- 0071621679/9780071621670 • Silbernagl, Lang: Color Atlas of Pathophysiology, George Thieme Verlag, 2000, ISBN: 9780865778665/9783131165510 • Kumar, Abbas, Fausto, Aster: Robbins & Cotran Pathologic Basis of Disease, 8th ed, Elsevier (Saunders title) 2010, ISBN: 978-1-4160-3121-5 • Goldman, Schafer: Goldman’s Cecil Medicine, 24th ed., Elsevier (Saunders title), 2012, ISBN: 978-1-4377-2788-3 • Longo, Fauci, Kasper, Hauser, Jameson, Loscalzo: Harrison’s Principles of Internal Medicine, 18th ed., McGraw-Hill Medical, 2012, ISBN 9780071748896/007174889X • Khan: Rapid ECG Interpretation 3rd ed., Humana Press Inc, 2008, ISBN: 978-1-58829-979-6 • Foster: Twelve-lead electrocardiography: theory and interpretation, 2nd ed., Springer-Verlag, 2007, ISBN-10: 1-84628-592-5 ISBN-13: 978-1-84628-592-9 • Wagner: Marriott's Practical Electrocardiography, 11th ed., Lippincott Williams & Wilkins, 2007, ISBN-10: 0781797381 ISBN-13: 9780781797382 • Bayés de Luna: Basic electrocardiography: normal and abnormal ECG patterns, Blackwell Publishing, 2007,

68 ISBN: 978-1-4051-7570-8 • Abedin & Conner: ECG Interpretation - The Self-Assessment Approach, 2nd ed., Blackwell Publishing, 2008, ISBN: 978-1-4051-6749-9 • Morris, Edhause, Brady, Camm: ABC of Clinical Electrocardiography, BMJ Publishing Group, 2003, ISBN 0 7279 1536 3 Handouts (for practice) • Fekete M.: Pathophysiology exercises II. 1987. • Szabó G.: Introduction to Electrocardiography 1999. MEDICAL PSYCHOLOGY • • • • • • •

Kent G., Dalgleish M.: Psychology and Medical Care, W.B. Saunders C.L.T.D. 1996. (compulsory) Suls J.M., Davidson, K. and Kaplan, R.M. (Eds): Handbook of Health Psychology and Behavioral Medicine. The Guilford Press, 2010. ISBN-10: 9781606238950 (compulsory) Andrew B. Crider: et all Psychology, Harper Collins College Publisher 1993. (recommended) Márta Csabai and Péter Molnár: Health, Illness, and Care. A textbook of medical psychology. Springer, Budapest, 2000. János Pilling (Ed): Medical Communication. Medicina, Budapest, 2011 Moira S. (2003): Patient-centered medicine: Transforming the clinical method. Radcliff Medical Press Ltd.

SURGERY (CLINICAL DIAGNOSTICS) • Ed.: Norton, Barie, Bollinger, Chang, Lowry, Mulvihill, Pass, Thompson, Shirazi: Surgery: Basic Science and Clinical Evidence (Book with CD-ROM), Springer, 2000., ISBN: 038798447X

BASICS OF EMERGENCY MEDICINE • Boros, M. (Ed.): Monitoring in Medical Practice. Basic Medical Skills. Innovariant Ltd., Szeged, 2007. ISBN 963-482-787-X • Boros, M. (Ed.): Practical Skills Syllabus. Innovariant Ltd., Szeged, 2007. ISBN 978-963-482-840-2 MICROSURGERY • Szabó, A., Vass, G., Zádor, Z., Boros, M.: Basics of Microsurgery. Manual for Medical Students. Szeged, 2004. (handout) • BASIC SURGICAL SKILLS, ADVANCED SURGICAL SKILLS • Boros, M. (Ed.): Surgical Techniques. Medicina, Budapest, 2009. ISBN 978-963-226-256-7 • Boros, M. (Ed.): Practical Skills Syllabus. Innovariant Ltd., Szeged, 2007. ISBN 978-963-482-840-2 • Kirk, R. M.: Basic Surgical Techniques, 6th Edition. Churchill Livingstone, 2010. ISBN: 978-0-7020-3390-2 BASIC IMMUNOPATHOLOGY • Abbas, A. K., Lichtman, A. H., Pillai, S: Cellular and Molecular Immunology. 7th Edition. Elsevier, Saunders, Philadelphia, 2011. ISBN: 978-0-8089-2425-8 LABORATORY MEDICINE • William J. Marshall: Clinical Chemistry, 4th, 5th or 6th Edition, MOSBY – Harcourt Publishers Ltd. 2008, ISBN 0-72-34-3159-0


69

Recommended textbooks for fourth year medical students ANAESTHESIOLOGY AND OXYOLOGY Recommended: • Keith G. Allman, Iain H. Wilson: Oxford Handbook of Anaesthesia, Oxford University Press, 2006. ISBN 0-19-856606-3 • Tim Craft, Jerry Nolan, Mike Parr: Critical Care, BIOS Scientific Publishers Ltd. 2009. ISBN 1-85996-2229-7 CASES IN CLINICAL MICROBIOLOGY • Cases in Medical Microbiology and Infectious Diseases, By Gilligan PH, Smiley ML, Shapiro DS, 3rd Edition, ISBN 10: 1555812074 / ISBN 13: 9781555812072, ASM, 2002. • Problem-Oriented Clinical Microbiology and Infectious Diseases, By Humphreys H, Irving WL, Hart CA, 2nd Edition, ISBN 0198515855, Oxford Medical Publication, 2004. • Atlas of Tropical Medicine and Parasitology, By Wallace Peters and Geoffrey Pasvol, 6th Edition, ISBN-13: 978 0-323-04364-9, Elsevier Mosby, 2007. CHILD AND ADOLESCENT PSYCHIATRY • Robert Goodman and Stephen Scott, Child Psychiatry, 1998 CLINICAL IMMUNOLOGY • Spickett, Gavin: Oxford Handbook of Clinical Immunology, Oxford University Press, 2006, ISBN:019262721x CLINICAL ONCOLOGY • AJCC Cancer Staging Manual, 2002 Springer • Cancer Management: A Multidisciplinary Approach, 2002 PRR Melvilla NY • Principles and Practice of Radiation Oncology Editors Carios A. Perez Luther W. Brandy., 1998 Lippincott-Raven • Radiation Oncology: Management Devisions. Editors K. S. Clifford Chao, Carlos A. Perez., 1999. LippincottRaven • The Washington Manual of Oncology. Editor Ramaswamy Gorindan, 2002 Lippincott HUNGARIAN LANGUAGE Obligatory: • GYİRFFY, Mária: Mi a panasz?, Idióma Bt. Pécs, 1999, ISBN 963 04 8860 4 INTERNAL MEDICINE Obligatory: • Hoffbrand, Moss: Essential Haematology, Wiley, 6th edition • Harrison’s Principles of Internal Medicine (2 Volume Set), Kasper, Dennis L. Braunwald, Eugene Fauci, Anthony Hauser, Stephen Longo, Dan Jameson, J., Larry, 16th ed., 2004, McGraw-Hill, ISBN: 0071391401 • Gibson, Costabel: Respiratory Medicine (2 Volume Set), 3rd ed., W. B. Saunders, 2002., ISBN: 0702026131 • Te-Chuan Chou: Chou’s Electrocardiography Clinical Practice, 5th ed., W.B. Saunders, 2001., ISBN: 0721686974 • Forster T., Csanády M.: Atlas of Colour Doppler Echocardiography, Szeged, 1991., • I.J. Mazza: Manual of Clinical Hematology, Oxford Textbook of Nephrology JS Cameron, AM Davison et al, Oxford University Press, 2001., ISBN: 078172907 • The Merck Manual of Diagnosis and Therapy, Merck and Co. Inc. 2006., ISBN: 0911910182 Recommended: • Stone: Harrison’s Principles of Internal Medicine: Self Assessment and Board Review: ISE, International Student Edition, McGraw-Hill, 2001., ISBN: 0071203591 • Brostoff: Clinical Immunology – An Illustrated Outline, Mosby, 1994, ISBN: 1563756641 • Stone: Current Emergency Diagnosis & Treatment, 5th ed., Appleton & Lange, 2004., ISBN: 0071219757 • Cheitlin: Clinical Cardiology, 7th ed. (to be published in January 2006), Appleton & Lange, ISBN: 0838513859 • Current Medical Diagnosis and Treatment 2006, Author(s): Lawrence M. Tierney, Jr., MD; Stephen J. McPhee, MD; Maxine A. Papadakis, MD, ISBN: 0071454101, Publication date: 2005, Edition 45th, ISBN: 034061370X LABORATORY DIAGNOSTICS: USE OF LABORATORY TESTS IN PRACTICE • William J. Marshall: Clinical Chemistry, 4th , 5th or 6th Edition, MOSBY – Harcourt Publishers Ltd., 2008, ISBN: 0-72-34-3159-0

70 NUCLEAR MEDICINE H.J. Biersack and L.M. Freeman. Clinical Nuclear Medicine; Springer 2007, ISBN 978-5-540-28025-5 OBSTETRICS AND GYNAECOLOGY • M. M. Garrey, A. D. T. Govan, C. Hodge, R. Callander: Obstetrics Illustrated, Fourth Edition, Churchill Livingstone, 1993., ISBN: 0443041806 • Fundamentals of Obstetrics, Zth ed., 1999, ISBN: 0723431507 • E. Malcolm Symonds: Essential Obstetrics and Gynaecology, Churchill Livingstone 1992, ISBN: 044304337X ORTHOPAEDICS • Miklós Szendrıi: Orthopedics. Semmelweis, Budapest 2008 PHARMACOLOGY • Katzung: Basic and Clinical Pharmacology, 10th Edition, McGraw-Hill Medical, 2007., ISBN: 007145136 • Rang & Dale’s Pharmacology, 6th ed., Churchill-Livingstone, 2007., ISBN: 0443069115, ISBN-13: 9780443069116 PUBLIC HEALTH Obligatory: • Paulik E (ed.): Public Health and Preventive Medicine. Medicina Publishing House, Budapest, 2013 Recommended: • Tulchinsky TH, Varavikova EA: The New Public Health. 2nd ed. Elsevier Academic Press, 2009, ISBN: 978-0-12370890-8 • Donaldson LJ, Donaldson RJ: Essential Public Health. 2nd ed. Petroc Press, 2003, ISBN:1900603B7X PULMONOLOGY • Isselbacher: Harrisons's: Principles of Internal Medicine I–II., 14th Edition, McGraw-Hill Book Company, 1998., ISBN: 0071133801 • S.J. Bourke: Lecture Notes On Respiratory Medicine, Sixth Edition, Blackwell Publishing, 2003 RADIOLOGY • Richard B. Gunderman, Essential Radiology, 3rd edition, Thieme, New Yorik, Stuttgart, 2007 SURGERY • Ed.: Norton, Barie, Bollinger, Chang, Lowry, Mulvihill, Pass, Thompson, Shirazi: Surgery: Basic Science and Clinical Evidence (Book with CD-ROM), Springer, 2000., ISBN: 038798447X STOMATOLOGY • R. A. Cawson: Essentials of Oral Pathology and Oral Medicine, Churchill Livingstone, 1-3 Baxters Place (Leith Warh, Edinburg, EHI 3AF), ISBN: 0443040427 • Szabó Gy.: Oral and Maxillofacial Surgery, 2nd ed., Semmelweis, Budapest, 2001. TROPICAL DISEASES • Manson's Tropical Diseases, By Gordon C. Cook, and Alimuddin I. Zumla, 22nd Edition, ISBN 978-1-4160-4470-3, Elsevier Inc., Imprint: Saunders Ltd., 2012. • Atlas of Tropical Medicine and Parasitology, By Wallace Peters and Geoffrey Pasvol, 6th Edition, ISBN-13: 978 0-323-04364-9, Elsevier Mosby, 2007.


71

Recommended textbooks for fifth year medical students CHILD AND ADOLESCENT PSYCHIATRY • Robert Goodman and Stephen Scott, Child Psychiatry, 1998 CLINICAL GENETICS • Harper, Peter, S: Practical Genetic Counselling, 2001. • Goodman, R.M. Golin, R.J: The Malformed Infant and Child, Oxford Univ. Press., 1983., ISBN: 0195032551 • Emery’s Elements of Medical Genetics, Mueller RF, Young ID, 11th Edition Churchill Livingstone, 2001 • Genetics, 2nd Edition National Medical Series for Independent Study., Williams and Wilkins, 1995. Friedman JM, Dill FJ, Hayden MR, McGillivray • Human Genetics . A problem-based approach B.R., Korf. 2nd,2000. CLINICAL MICROBIOLOGY • Peter H. Gilligan, Daniel S. Shapiro and M. Lynn Smiley: Cases in Medical Microbiology and Infectios Diseases, Publisher: Amer Society for Microbiology, Published Date: 1992, ISBN 1555810454 • Hilary HUmphreys, William L. Irving: Problem-Oriented-Clinical Microbiolgy and Infection, 2nd Edition, Publisher: Oxford University Press, 2004, ISBN: 0198515855 • W. Peters.H.M.Gilles: Color Atlas of Tropical Medicine and Parasitology, 4th Edition, London, Mosby, Wolfe, 1995, ISBN: 0723420696 CLINICAL PHARMACOLOGY • Oxford Textbook of clinical pharmacology and drug therapy (Eds. Grahame-Smith, Aronson), Lecture notes on clinical pharmacology (Eds. Reid, Rubin, Whiting) DERMATOLOGY • J. A. A. Hunter, J. A. Savin, M. V. Dahl: Clinical Dermatology, Blackwell Scientific Publications 2nd ed., ISBN: 0632037148 FORENSIC MEDICINE • Richard Shepeherd: Simson's Forensic Medicine 12th edition, 2003 Hodder Arnold and Hachette UK Company ISBN 978 0 340 76422 0 • Lecture Notes of Forensic Medicine (Ed.: P. Sótonyi, E. Keller), Semmelweis Publisher, 2008. ISBN 978 963 9656 92 5

INTERNAL MEDICINE Obligatory: • Harrison’s Principles of Internal Medicine (2 Volume Set), Kasper, Dennis L. Braunwald, Eugene Fauci, Anthony Hauser, Stephen Longo, Dan, 16th ed., 2004., McGraw-Hill, ISBN: 0071391401 • Te-Chuan Chou: Chou’s Electrocardiography Clinical Practice, 5th ed., W.B. Saunders, 2001., ISBN: 0721686974 • Forster T., Csanády M.: Atlas of Colour Doppler Echocardiography, Szeged, 1991. • I.J. Mazza: Manual of Clinical Hematology, Oxford Textbook of Nephrology JS Cameron, AM Davison et al, Oxford University Press, 2001., ISBN: 078172907 • The Merck Manual of Diagnosis and Therapy, Merck and Co. Inc. 2006., ISBN: 0911910182 Recommended: • Stone: Harrison’s Principles of Internal Medicine: Self Assessment and Board Review: ISE, International Student Edition, McGraw-Hill, 2001., ISBN: 0071203591 • Stone: Current Emergency Diagnosis & Treatment, 5th ed., Appleton & Lange, 2004., ISBN: 0071219757 • Current Medical Diagnosis and Treatment 2006, Author(s): Lawrence M. Tierney, Jr., MD; Stephen J. McPhee, MD; Maxine A. Papadakis, MD, ISBN: 0071454101, Publication date: 2005, Edition 45th LABORATORY DIAGNOSTICS: USE OF LABORATORY TESTS IN PRACTICE • William J. Marshall: Clinical Chemistry, 4th , 5th or 6th Edition, MOSBY – Harcourt Publishers Ltd., 2008, ISBN: 0-72-34-3159-0 NEUROLOGY • Rowland, L.P: Merritt's Textbook of Neurology, Lea and Febiger, Philadelphia, 1995., ISBN: 0683074008

72 • •

Simon, R. P., Aminoff, M. J., Greenberg, D. A: Clinical Neurology, Appleton and Lange, 1993., ISBN: 0838514782 Adams, R., Victor, M: Principles of Neurology, McGraw Hill, 1996., ISBN: 0070674396

NEUROSURGERY • Andrew Kaye: Essential Neurosurgery, Churchill Livingstone, ISBN: 0443043507, available online: https://archive.org/details/EssentialNeurosurgery • Mark S. Greenberg – Handbook of Neurosurgery (ISBN: 978-1-60406-326-4) OPHTHALMOLOGY

• Thieme Flexi Book, Gerhard K. Lang, Ophthalmology, A Pocket Textbook Atlas, Thieme 2000., ISBN: 313126161-7 (GTV), ISBN: 0865779368 (TNY) • Differiential Diagnosis in Ophthalmology, Stephen A. Vernon, Manson Publishing 1999., ISBN: 1874545901 OTO-RHINO-LARYNGOLOGY • W. Becker, H.H. Naumann, C.R. Pfaltz: Ear, Nose and Throat Diseases, A Pocket Reference, Georg Thiemes Verlag Stuttgart, New York 1996., ISBN 3-13671201-3 • Sziklai: Oto-Rhino-Laryngology Lecture notes 1994. (handout), Order from: Semmelweis Orvostudományi Egyetem Képzéskutató, Oktatástechnológiai és Dokumentációs Központ, Budapest • Carl RudolfPfaltz: Ear, Nose and Throat Diseases –A Pocket Reference, Thieme Medical Publishers, Inc., 1994., ISBN: 3136712021 • Simson Hall, Bernard H. Colman: Diseases of the Nose, Throat and Ear, A Handbook for Students and Practitioners, 1992., ISBN: 0443045631 PAEDIATRICS • David Hull, Derek I. Johnston: Essential Pediatrics, Churchill Livingstone 4th ed. 1999., ISBN: 0443059586 or • • •

Op Ghai: Essential Pediatrics, Fifth Edition Richard E. Behrman, Robert M. Kliegmann: Nelson Essentials of Pediatrics, Fourth edition Tom Lissauer, Graham Clayden: Illustrated Textbook of Pediatrics, Mosby 2nd ed. 2001., ISBN: 0723431787

PSYCHIATRY • Z. Janka: One Page Synopsis - Abstracts of Psychiatry Lectures, handout. • B.J. Sadock - V.A. Sadock: Kaplan & Sadock's Concise Textbook of Clinical Psychiatry. Lippincott Williams & Wilkins, Philadelphia, latest edition, ISBN 0-7817-5033-4 or any of the following books: • • • • •

N.C. Andreasen - D.W. Black: Introductory Textbook of Psychiatry. American Psychiatric Press: Washington, D.C., latest edition. ISBN: 0-88048-705-4 R.J. Waldinger: Psychiatry for Medical Students. American Psychiatric Press: Washington, D.C. latest edition. H.H. Goldman: Review of General Psychiatry. Appleton and Lange, Norwalk, CT., latest edition. ISBN 0-8385-8421-7; ISBN 089-2404 H.I. Kaplan - B.J. Sadock: Synopsis of Psychiatry. Behavioral Science, Clinical Psychiatry. Lippincott Williams and Wilkins, Baltimore, MD, latest edition. Szilárd J. - Janka Z.: Elements of Social Psychology. Univiversity Meddical School Press, Szeged

RHEUMATOLOGY • Harrison’s Principles of Internal Medicine (2 Volume Set), Kasper, Dennis L. Braunwald, Eugene Fauci, Anthony Hauser, Stephen Longo, Dan Jameson, J., Larry, 16th ed., 2004, McGraw-Hill, ISBN: 0071391401 SURGERY • Ed.: Norton, Barie, Bollinger, Chang, Lowry, Mulvihill, Pass, Thompson, Shirazi: Surgery: Basic Science and Clinical Evidence (Book with CD-ROM), Springer, 2000., ISBN: 038798447X


73

UROLOGY • Smith: General Urology, Appleton and Lange, 14th ed. 1994., ISBN: 0838586139 TRAUMATOLOGY • James D. Hardy: Hardy's Textbook of Surgery, J.B. Lippincott Company, Philadelphia, 1990, ISBN: 0397508182

74 SYLLABUSES BASIC AND PRE-CLINICAL MODULE - MEDICINE ANATOMY, HISTOLOGY AND EMBRYOLOGY 1st semester LECTURE (2 hrs/week) * General anatomy Terminology (planes, directions, parts of the human body) General osteology General syndesmology *

General myology General angiology

DISSECTION PRACTICE ANATOMY SEMINAR (3 hrs/week) (2 hrs/week)

Rules, regulations of the dissection room Bones, joints of the thorax(vertebrae,ribs, sternum)

Upper limb Bones and joints of the upper limb (UL).

Bones, joints of the upper limb

Muscles of the UL.

Dissection of the muscles of the upper limb.

Arteries and veins of the UL. Branches of the axillary artery. Lymph vessels of the UL.

Main branches of the aorta and SVC-IVC *

General neurology. Brachial and lumbosacral plexuses.

*

Functional- and clinical anatomy of the UL. Dissection of the vessels and nerves of the upper limb.

*

Trunk anatomy Anatomy of the vertebral column (bones

1.MTO:

Branches of the brachial plexus on the UL. Nerve injuries on the UL. Lower limb

UL, Bones, joints of the thorax Functional anatomy of the joints of the lower limb (LL).

and joints). Thorax: bones and joints. Movements of the spine and rib cage. *

Functional anatomy of back muscles. The thoracolumbar fascia. Anatomy of the

Bones, joints of the lower limb.

Muscles of the hip and pelvis. Muscles of the LL. Fasciae of the LL.

chest wall muscles. *

*

Anatomy, blood supply, lymphatics of the breast (mammary gland) Diaphragm, muscles of respiration Basic tissues

Epithelia, connective tissues. *

Cartilage, bone tissue, ossification. Muscle tissue.

Dissection of the muscles of the lower limb.

Functional anatomy of the blood vessels of the LL. Lymph nodes and vessels of the LL.

Dissection of the vessels, nerves of the lower limb.

23-24.October holiday

Innervation of the LL. Motorand sensory nerves on the LL (nerve injuries).

Dissection of the vessels, nerves of the lower limb.

Functional- and clinical anatomy of the LL. Functional anatomy of the abdominal wall: muscles, fasciae. Inguinal canal, rectus sheath, hernia canals.

*

Nerve tissue. Receptors, effectors.

Study of the bones of the trunk (vertebrae, ribs, sternum) on human samples and on radiographic pictures.

*

Circulatory- and respiratory anatomy Anatomy, histology of the heart, pericardium.

Dissection of the chest- and back muscles. Dissection of the intercostal space.

Skull Bones of the skull. Sutures and joints. The concept of viscerocranium and neurocranium.


75

*

Anatomy, histology of the nasal cavity and the paranasal sinuses.

Structure of the abdominal wall, abdominal muscles, rectus sheath, inguinal canal.

External and internal cranial basis: bony structures and contents.

*

Anatomy, histology of the larynx.

Bones of the skull. External, internal cranial base.

Nasal cavity, oral cavity, orbit, infratemporal- and pterygopalatine fossae (bony structures and contents).

*

Anatomy, histology of the trachea and the bronchial tree.

2.MTO:

Discussion of the topics of the semester: tutorial on the radiological images (UL, LL, trunk, skull).

Skull, LL, Trunk anatomy.

* 2nd semester LECTURE (2 hrs/week)

DISSECTION PRACTICE (3 hrs/week)

Alimentary System Thoracic Cavity, The anatomy and histology of the oral Cardiovascular and cavity; teeth, large salivary glands, and the Respiratory System tongue. The anatomy of the mediastinum. Dissection of the superior mediastinum. *

The anatomy and histology of the, pharynx The anatomy of the heart and the oesophagus. and the pericardium. The anatomy of the peritoneum.

MICROSCOPY PRACTICE (2 hrs/week) Basic tissues I.: Epithelial tissues:

Kidney (HE) Trachea (HE) Esophagus (HE) Skin (HE) Basic tissues II.: Connective and supporting tissues:

Skin (HE) Ear (Orcein) Bone (ground section) Enchondral ossification (HE) *

*

*

*

The anatomy and histology of the stomach, small intestine, large intestine and the rectum. The topography, anatomy and histology of the spleen.

Removal and dissection of the lungs and the bronchial tree. Dissection of the posterior mediastinum and the intercostal space.

Basic tissues III.: Muscle tissues and nervous tissue

The anatomy, blood circulation and histology of the liver and the gall bladder. The anatomy and histology of the pancreas.

The anatomy of the nasal cavity, nasopharynx and the paranasal sinuses. The anatomy of the larynx.

Histology of the blood vessels and the respiratory system

Blood supply, lymphatic drainage and innervation of the organs of the abdominal cavity. Topography of the abdominal organs.

Practical assessment: Anatomy of the thoracic cavity, mediastinum, heart, and the respiratory system. (nasal cavity, larynx, trachea and lungs)

Urogenital System Gross anatomy, blood supply and histology of the kidney. Anatomy and histology of the ureter, urinary bladder and the urethra.

Abdominal Cavity and the Digestive System Abdominal regions, abdominal situs and projection of the viscera. Opening of the abdominal cavity, inspection of the viscera. Dissection of the lesser and

Smooth muscle (HE) Skeletal muscle (HE) Cardiac muscle (HE) Peripherial nerve (HE) Sensory ganglion (HE) Aorta (resorcin-fuchsin) Artery & Vein (HE) Trachea (HE) Lung (HE) Histology of the digestive system I.

Lip (HE) Dorsum linguae (HE) Circumvallate papilla (HE) Parotid gland (HE) Submandibular gland (HE) Histology of the digestive system II.

Esophagus (HE) Cardia (HE) Fundus, corpus (HE) Duodenum (HE) Jejunum (HE) Jejunum (PAS) Ileum (HE)

76

*

*

The anatomy and histology of the male genital organs. The anatomy and histology of the female genital organs.

The anatomy of the male and female perineum. Topography of the lesser pelvis.

greater omentum, the omental bursa, the recesses of the peritoneum. Dissection of the stomach, the small and large intestines. Examination of the liver and the pancreas. Dissection of the hepatoduodenal ligament. Dissection of the retroperitoneum: kidneys, ureters, posterior abdominal wall.

Histology of the digestive system III.

Large intestine (HE) Vermiform appendix (HE) Anal canal (HE)

Practical assessment: Histology of the heart and blood vessels Histology of the respiratory and digestive systems Practical assessment: Histology of the liver and the Anatomy of the alimentary pancreas tract and the abdominal Liver (HE) cavity. Liver (Kupffer-cells)

Gall bladder (HE) Pancreas (HE) *

*

*

*

*

Blood, Hematopoies and the Lymphatic System Histology of the blood. Hematopoiesis. Histology of the immune system and lymphoid organs.

Lesser Pelvis and Perineum Dissection of the scrotum, testis and epididymis. Topography of the male pelvis. Dissection of the female genital organs. Topography of the female pelvis.

Uropoietic system:

Kidney (HE) Ureter (HE) Urinary bladder (HE) Urethra (HE) Male genital organs I.:

Testis-epididymis(HE) Spermatic cord(HE) Seminal vesicle(HE) Prostate (HE) Penis(HE

Endocrine System The pituitary gland and the neuroendocrine regulation.

Dissection of the male and female perineum. Ischiorectal fossa, pudendal canal.

Female genital organs:

The anatomy and histology of the thyroid and parathyroid glands. The endocrine pancreas and the enteroendokrin system.

Practical assessment: Anatomy of the lesser pelvis and urogenital organs

General recapitulation

The suprarenal gland, and the endocrine cells of the gonads. Histology of the diffuse neuroendocrine system.

General recapitulation

Practical assessment: Histology of the urogenital system Histology of the liver and the pancreas

Repetition

Ovary (HE) Oviduct(HE) Uterus(HE) Uterine cervix(HE) Repetition

*

*

3rd semester LECTURE (2 hrs/week) Fine structure of the grey matter of the spinal cord. Tracts of the white matter.

DISSECTION PRACTICE (3 hrs/week)

HISTOLOGY PRACTICE (2 hrs/week)

Rules, regulations of the dissection room.

General information, rules and regulations.

CNS. Opening of the skull, removal of the brain, duplicatures of the dura mater, meningeal spaces. Vertebral canal preparation, meninges of the

Blood smear (MGG) Red bone marrow (HE) Thymus (HE)


*

Fine structure of the medulla oblongata, pons, mesencephalon. Reticular formation.

*

Synaptology, histology of the cerebellum. Neuroanatomy of the cerebellar motion regulation.

*

Diencephalon: fine structure of the thalamus and the hypothalamus. Neurosecretion.

*

Basal ganglia, extrapyramidal system.

*

Neocortex, allocortex: function, histology, transmitters. Commissural, associational pathways. Rhinencephalon, limbic system.

*

77 spinal cord, spinal cord preparation. Hemispheres, gyri, sulci, lateral ventricles. Circle of Willis, blood supply of the hemispheres.

Lymphnode (HE) Spleen (HE) Palatine tonsill (HE) Root of the tongue (HE)

Anatomy of the diencephalon, III. ventricle, FLECHSIG’s section, internal capsule, basal ganglia. Brainstem, IV. ventricle, romboid fossa. Exit of the cranial nerves (brainstem, skull).

CNS SEMINAR: Cross-sections of the brainstem I., classification of cranial nerve nuclei CNS SEMINAR: Cross-sections of the brainstem II.,brainstem nuclei. Branchings of the cranial nerves.

Anatomy and topography of the cerebellum. Cerebellar nuclei. External, internal base of the skull. Summary of the cavities of the skull.

CNS SEMINAR: Summary of the ascending and descending pathways. Sensory nerve ending (HE) Sensory nerve ending (Ag) Spinal cord (HE) Cerebellum (HE) Neocortex (HE)

Meninges. Blood supply of the CNS, ventricles, CSF circulation.

1.MTO: CNS.

*

Anatomy, histology of the eye. Structure, blood supply of the retina. Accessory organs, muscles of the eye.

HEAD and NECK Muscles of mastication- and facial expression. Muscles of the neck.

Hypophysis (HE) Thyroid gland(HE) Parathyroid gland (HE) Adrenal gland (HE) Corpus luteum (HE) Pancreas (HE) Eye (HE) Eyelid (HE) Lacrimalgland (HE)

*

Neuroanatomy of the visual pathway. Light reflex of the pupil. Eye movements – pathways. Anatomy, histology of the external and middle ear. Anatomy of the inner ear: osseous, membranaceous labyrinth.

Arteries, veins, lymphatics of the head, neck

Skin (HE) Hairy skin (HE)

Cervical plexus, skin innervation of the head & neck

Placenta (HE) Mammary gland(HE)

*

Organ of Corti: fine structure of the cristae, maculae. Auditory, vestibular pathways.

Repetition

*

Ovulation, fertilisation. Cleavage, blastocyst, implantation, formation of the placenta.

Topography of the head & neck. Dissection of the paranasal sinuses. Mediansagittal section of the head & neck. Topography of the cranial base, orbita, tympanic cavity.

*

*

Developement of the embryo: gastrulation and neurulation. Developement of the amnion and the yolk sac. The folding of the embryo.

2.MTO:

Head & neck, periferial branches of the cranial nerves, sense organs.

MTO:

Blood, haemopoesis, lymphatic system, nervous system, endocrine system, sense organs, skin, mammary gland, placenta Histology consultation for the anatomy final exam

78 *

The formation of the branchial apparatus: blood and nerve supply, derivatives. Summary of the main points of the embryonal and fetal periods.

Dissection room consultation for the final exam

Histology consultation for the anatomy final exam

MTO Retake.

BIOCHEMISTRY 3rd semester

* *

* * * * * * * * * *

*

*

LECTURE (3 hrs/week) Proteins and bioenergetics: structure and function of proteins, thermodynamics of living systems Enzymology: enzyme classes, coenzymes, characterisation of enzymes, isoenzymes, multienzyme systems

PRACTICE (2 hrs/week) General information, work safety and laboratory work Substrate specificity and temperature optimum of amylase enzyme activity Enzymology: molecular mechanism of catalysis, enzyme kinetics, Determination of protein modulation and regulation of enzyme activity concentration Carbohydrate metabolism: Digestion and absorption of carbohydrates, Seminar: proteins and glycolysis, gluconeogenesis, pyruvate dehydrogenase enzyme complex enzymes* Carbohydrate metabolism: glycogen metabolism, pentose phosphate cycle Assay of activity of alkalnine and glucuronide shunt phosphatase Carbohydrate metabolism: Fructose and galactose metabolism, Seminar: carbohydrate glycoproteins, regulation of blood glucose level, diabetes mellitus metabolism* Lipid metabolism: Digestion and absorption of lipids, lipoprotein Determination of glucose-6metabolism, lipid mobilisation, oxidation of fatty acids, ketone bodies phosphatase enzyme activity Lipid metabolism: Synthesis of fatty acids, synthesis of triacyl glycerols and Seminar: lipid metabolism* sphingolipids, cholesterol and steroid metabolism Amino acid metabolism: Digestion and absorption of proteins, catabolism MTO of amino acids, fate of amino group, urea cycle Amino acid metabolism: catabolism of amino acids, fate of carbon Determination of uric acid skeleton of amino acids, one-carbon units, glutathione concentration Synthesis of hem and porphyrine, enterohepatic circulation of hem Seminar: amino acid degradation products metabolism* Nucleotide metabolism: synthesis and degradation of purine and pirimidine Investigation of oxygen nucleotides, salvage pathways, synthesis of deoxyribonucleotides consumption of isolated mitochondria Citric acid cycle: steps and regulation of the cycle, relationship between Seminar: nucleotide the cycle and other metabolic pathways metabolism, citric acid cycle, respiratory chain, oxidative phosphorylation* Mitochondrial transport systems, mechanism of respiratory chain and Consultation oxidative phosphorylation

4th semester LECTURE

SEMINAR

PRACTICE

*

Proteins and bioenergetics: structure and function of proteins, thermodynamics of living systems

General information, work safety, principles of lab work

*

Enzymology: enzyme classes, coenzymes, characterisation of enzymes, isoenzymes, multienzyme systems

Determination of protein concentration

*

Enzymology: molecular mechanism of catalysis, enzyme kinetics, modulation and regulation of enzyme activity

Substrate specificity and temperature optimum of amylase enzyme activity


79

*

Carbohydrate metabolism: Digestion and SEMINAR absorption of carbohydrates, glycolysis, (proteins, pyruvate dehydrogenase enzyme complex, enzymes) gluconeogenesis

*

Carbohydrate metabolism: Fructose and galactose metabolism, glycogen metabolism, pentose phosphate cycle and glucuronide shunt

*

Carbohydrate metabolism: regulation of blood glucose level, glycoproteins

Assay of activity of alkaline phosphatase

SEMINAR (carbohydrate metabolism)

Lipid metabolism: Eicosanoids, digestion and absorption of lipids, lipoprotein metabolism *

Lipid metabolism: lipid mobilisation, oxidation of fatty acids, ketone bodies, diabetes mellitus

*

Lipid metabolism: Synthesis of fatty acids, synthesis of triacyl glycerols and phospholipids, sphingolipids, cholesterol and steroid metabolism

*

Amino acid metabolism: Digestion and SEMINAR (lipid absorption of proteins, catabolism of metabolism) essential amino acids, fate of amino group, urea cycle

*

Amino acid metabolism: metabolism of non-essential amino acids, fate of carbon skeleton of amino acids, one-carbon units, glutathione

*

Amino acid metabolism: Synthesis of hem and porphyrine, enterohepatic circulation of hem degradation products

*

Citric acid cycle: steps and regulation of the cycle, relationship between the cycle and other metabolic pathways

Determination of glucose-6phosphatase activity

1st MTO

Determination of triacyl glycerol and cholesterol

SEMINAR (amino acid metabolism)

SEMINAR (citric acid cycle, respiratory chain, oxidative phosphorylati on) 2nd MTO

*

Mitochondrial transport systems, mechanism of respiratory chain and oxidative phosphorylation

Investigation of the oxygen consumption of isolated mitochondria

*

Nucleotide metabolism: synthesis and degradation of purine and pirimidine nucleotides, salvage pathways, synthesis of deoxyribonucleotides

Nucleotide metabolism Determination of uric acid concentration

80

CELL BIOLOGY AND MOLECULAR GENETICS 1st semester

* * * * * * * * * * * * * *

LECTURE (2 hrs/week) Structure and operation of the cell The DNA Transcription, translation & proteins Mutation &jumping genes Bacterial genetics Genetic regulation in eukaryotes Mendelian and non-Mendelian genetics Epigenetics Genes and traits Genetic diseases Evolution Cytoskeleton & membrane processes Molecular biology of viruses Frontiers of molecular and cell biology

PRACTICE (2 hrs/week) Handling of technical devices Microscopy-1 Microscopy-2 DNA and RNA purification Genetic exercises Separation techniques Lac operon & consultation

2nd semester

* * * * *

LECTURE (2 hrs/week) Human genome Genetically modified organisms & cloning Cell cycle & tumor formation Molecular medicine Cell signalling-1

* * * * * * * * *

Cell-signalling-2 Cell communication & tissue differentiation Genetic regulation of ontogenesis Neural communication & consciousness Molecular biology of sensation Immunogenetics Molecular evolution Genetics of behaviour Genetic disease of brain and psyche

PRACTICE (2 hrs/week) Molecular cloning PCR & DNA sequencing Detection of DNA and RNA Detection of proteins DNA and protein chips, DNA finger printing Genetic exercises Reporter genes & consultation

FIRST AID AND RESUSCITATION 1st semester

* * * * * * * *

PRACTICE (2 hrs/week) Principles of first aid. Emergency situations. Victim assessment routine. Assessing respiration and pulses. Normal and abnormal pulse rates per minute. The unresponsive patient. Terms of position. Extrication of the injured patient (Rautek manoeuvre). Basic life support. Victim assessment and positioning. Determine unresponsiveness. Assess for breathlessness. Provide rescue breathing. Circulation. Esmarch-Heiberg manoeuvre. BLS (one-person CPR, two-person CPR) Obstructed airway emergencies. Heimlich manoeuvre. Paediatric basic life support. Bleeding (haemorrhage). Bleeding from an artery, from a vein. General procedures for controlling bleeding. Direct and indirect pressure. Arterial pulse points. Recognition of patients with shock condition. Body positioning for preventing shock.

Curriculum 2014/2015 * * * * * *

81

Classification of open wounds. Bandaging. Burn injuries. Electrical injuries. Heat and cold emergencies. Water accident. Mechanism of injury. Types of injury to joints and bones. Splints. Head injuries. Injuries to the spine. Injuries to the chest. Injuries to the abdomen. Poisoning. Heart attack. Respiratory emergencies. Revision of BLS.

MEDICAL CHEMISTRY 1st smester (14 weeks) WEEK 1.

2.

3.

4.

5.

6.

LECTURE

SEMINAR

PRACTICE

(3 hrs/week)

(1 hr/week)

(2 hrs/week)

Basic terms. The mole concept. Basic structure of atoms. Electronic structure of atoms. Atomic theories. The periodic table. Explanation of periodic properties. Chemical bonding. Octet rule. Ionic bonding. Ionic solids, monatomic and polyatomic ions. Metallic bonding. Covalent bonds. Characterization of molecules. Dipole moment. Molecular geometry. Intermolecular forces: hydrogen bonding and van der Waals forces (dipole-dipole and London forces). Introduction to inorganic chemistry. Properties of the most important metals and their compounds. Biological importance and usage. Complex ions. Properties of the most important nonmetals and their compounds. Biological importance and usage. Formation and physiological effects of free radicals. Types of metathesis reactions. States of matter. Gas laws and Avogadro's law. Properties of liquids, dependence of phase changes on pressure and temperature. Properties of solids, types of crystalline lattice. Homogenous and heterogenous systems. Colloids. Solutions. Types of solutions. The solution process. Ways of expressing concentration. Colligative properties. Osmosis and its biological importance. Chemical equilibrium.

Important terms: atomic mass, molar mass, moles, chemical formulas. Chemical reactions, stoichiometry, SI units, simple chemical calculations involving Avogadro’s number and moles. Atomic models, electronic configuration of atoms. Chemical calculations: concentration of solutions.

Review of laboratory requirements. Fire and safety precautions. Demonstration of laboratory equipments.

The application of the periodic table. Continuation of practicing simple chemical calculations.

Background of volumetric analysis. Using a pipette and a burette. Titration calculations.

The principle of photometry, Lambert-Beer law.

Intra- and intermolecular Potentiometry, pH measurements. chemical bonds. Continuation of practicing simple chemical calculations.

Metals and nonmetals and their compounds. Complexes. Summary of inorganic chemical reactions.

During weeks 5 to 12 students work in rotation and conduct one of the following experiments each week:

Solutions.

I) Quantitative determination of HCl content by titration with NaOH solution. II) Determination of pKa of a known concentration weak acid solution through the preparation of different buffers. III) Measurement of buffer capacity. IV) Qualitative analysis (2 weeks).

82

7.

8.

9.

10.

11.

12.

13.

LeChatelier's principle. Electrolytic dissociation, strong and weak electrolytes. Acid-base concepts. Equilibrium in electrolytes, pH and pOH. Acid-base ionization equilibrium. Salts. Solubility of electrolytes. Hydrolysis of salts. Acidic and basic anhydrides. Acid-base titration. Buffers and their biological importance. Thermochemistry. Basic terms. First, second and third laws of thermodynamics. Entropy and disorder. Change in Gibb's free energy and spontaneity of a reaction. Electrochemistry. Oxidationreduction reactions. Electrical work and free energy change.

Osmosis.

V) Quantitative determination of Fe(II)-content by permanganometric titration measuring the redox potential. VI) Complexometric determination of calcium and magnesium. VII) Photometric determination of iron. VIII) Photometric determination of Chemical equilibrium. Application glucose. of LeChatelier’s principle. Acid-base concepts. Simple pH calculations.

Voltaic cells, types of electrodes. Reference electrodes. Glass electrodes, measurement of pH. Electrolysis. Reaction kinetics. Rate, order, molecularity and mechanism of reactions. Complex chemical reactions. Catalysis. Enzymes as biocatalysts. General principles of organic chemistry. Classification of organic compounds. Functional groups. Types of organic chemical reactions: substitution, addition, and elimination. Types of isomerism. Alkanes (paraffin hydrocarbons). Cycloalkanes. Alkenes. Alkynes. Isoprene, mevalonic acid, terpenes. Carotinoids. Vitamin A. The photochemistry of vision. Polarization in organic compounds: inductive and conjugation effects. Structure of conjugated dienes. Absorption of light, color compounds. Aromatic hydrocarbons. Structure and reactions of benzene and its derivatives. Organic halogen compounds. Hydroxyl group containing organic compounds: alcohols, enols and phenols. Classification, nomenclature and chemical properties of alcohols. Some important

Brief summary of chemical thermodynamics. Electrochemistry. Electrode potential. Balancing redox reaction equations.

Buffers, calculations involving buffers.

Voltaic cells. Calculations involving the Nernst equation. Reaction kinetics. Catalysis.

Saturated hydrocarbons: alkanes and cycloalkanes. Unsaturated hydrocarbons: alkenes and alkynes.

Inductive and conjugation effects in organic compounds. Aromatic hydrocarbons.

Weeks 12 and 14: make-up laboratory practicals.

Curriculum 2014/2015 14.

alcohols. Esters of alcohols formed with inorganic acids. Phenols. Acidity of phenols. Nomenclature and chemical reactions of phenols. Oxidation of phenols, quinones. Ethers. Thioalcohols, thioethers, sulfoxides and sulfones.

83 Organic halogen compounds. Alcohols and phenols. Ethers and sulfur-containing organic compounds.

2nd smester (14 weeks) WEEK

LECTURE

SEMINAR

PRACTICE

(3 hrs/week)

(1 hr/week)

(2 hrs/week)

1.

Three-dimensional structure of molecules: Summary of organic constitution, configuration and conformation. chemical reactions. Optical isomerism. Enantiomers, racemates. Configuration: D-L and R-S systems. Molecules with more than one chiral centers. Diastereomers.

2.

Classification and nomenclature of amines. Basicity of amines, salt formation. Biologically important amines and aminoalcohols. Amines as neurotransmitters. Reactions of amines. Azodyes, sulfonamides and their chemotherapy. Classification and nomenclature of heterocyclic compounds. Three- and four-membered heterocycles: beta-lactams. Five-membered heterocycles with one and two heteroatoms. Six-membered heterocycles with one heteroatom: nicotinamide, flavonoids. Sixmembered heterocycles with two heteroatoms: pyrimidines, barbituric acid and barbiturates. Purines. Uric acid. Oxo compounds. Structure of the carbonyl group. Chemical reactions of aldehydes and ketones: addition and condenzation reactions. Enol-oxo tautomerism and aldol dimerization of oxo compounds. The role of these reactions in biochemical processes. Oxidation and reduction reactions. Important oxo compounds: quinones, coenzyme Q and vitamin K. Classification and nomenclature of carboxylic acids. Acidity, salt formation. Homologous series of saturated and unsaturated carboxylic acids. Fatty acids. The role of eicosapentaenic and docosahexaenic acids in biological membranes. Prostaglandines. Dicarboxylic acids. Unsaturated and hydroxy carboxylic acids. Oxo acids, "ketone bodies". Derivatives of carbonic acid: urea, guanidine, creatine, phosphocreatine. Carboxylic acid derivatives: esters,

3.

4.

5.

Chirality, optical isomerism.

Demonstration of laboratory equipments used for preparative organic chemistry. Examination of some important functional groups: - detection of the double bond - electrophilic substitution of aromatic compounds - reactions of alcohols Modeling of chirality.

Amines.

Examination of some important functional groups: - reactions of amines - reactions of oxo compounds - acidity and basicity of organic compounds

Heterocyclic compounds.

During weeks 4 to 11 students work in rotation and conduct one of the following experiments each week: I) Complexometric determination of calcium and magnesium. II) Photometric determination of iron. III) Photometric determination of glucose. IV) Kinetic examination of the hydrolysis of an ester. V) Polarimetric determination of sugar. VI) Quantitative determination of a protein by photometric method.

Aldehydes, ketones, and quinones.

84

6.

7.

8.

9.

10.

11.

12.

thioesters, acyl halides, anhydrides, amides. Acylation reaction, acylating agents. Acid-catalyzed esterification and hydrolysis of esters. Soaps, detergents. Phosphoglycerydes. Plasmalogens. Sphingolipids. The structure of biological membranes. Classification and nomenclature of amino acids. Proteinogenic amino acids. Amphoteric character: isoelectric points. Essential amino acids, biological importance. Qualitative tests, preparation and separation of amino acids. Chemical properties. Peptides. Stereochemistry of the peptide bond. Principles of sequence analysis. Synthesis of peptides. Biological importance of peptides. Naturally occurring peptides. Important peptide hormones, analogues and peptide antibiotics. Structure and function of proteins. Physical and chemical properties, purification and classification of proteins. Qualitative tests. The three-dimensional structure of proteins. Protein folding. Denaturation of proteins. Biological importance of proteins: transport, contractile, structural, nutrient, storage, defense and regulation proteins. Mechanism of enzyme reactions. Classification of carbohydrates. Configuration. D-glucose, mutarotation, anomers. Cyclic structures. Chemical properties of monosaccharides: oxidation, reduction, formation of ethers and esters, formation of O- and N-glycosides. Important monosaccharides: aldoses and ketoses and their derivatives. Structure of disaccharides. Nonreducing disaccharides: sucrose and trehalose. Reducing disaccharides: maltose, cellobiose, lactose. Oligosaccharides. Complex oligosaccharides. Mucopolysaccharides: hyaluronic acid, chondroitin and its sulfate, dermatane sulfate and heparine. Polysaccharides: starch, glycogen, cellulose. Structure of bacterial cell wall. Steroids. Classification of steroids. Cholesterol, cholesterolesters. Ergosterol. Vitamins D2 and D3. Bile acids and their detergent effect. Steroid hormones. Corticosteroids: mineralo- and glucocorticosteroids. Sex hormones. Structure and properties of nucleosides and nucleotides. Nucleic acid bases (uracil, thymine, cytosine, adenine, guanine). Nucleotide coenzymes:NAD and NADH. Nucleic acids: RNA and DNA. Hydrolysis, purification and properties of nucleic acids. Sequence analysis and synthesis of nucleic acids. Structure of DNA: double helix. BDNA, A-DNA and Z-DNA. Denaturation of DNA. DNA-protein complexes.

Carboxylic acids. Substituted carboxylic acids.

VII) Photometric cholesterol determination. VIII) Quantitative determination of vitamin C content by bromatometric titration.

Carboxylic acid derivatives. Lipids.

Amino acids.

Peptides and proteins.

Mono- and disaccharides.

Oligo- and polysaccharides.

Bioorganic chemistry: some chemical reactions of proteins and carbohydrates.

Steroids.

Weeks 12 to 14: make-up laboratory practicals.


14.

85

Biological importance of nucleic acids. Classification of RNA. Molecular mechanism of protein biosynthesis, genetic code. Water-soluble vitamins and their coenzymes. Fat-soluble vitamines. Hypo- and hypervitaminosis. Alkaloids, most important representatives. Antibiosis. Classification of antibiotics. Most important antibiotics. Porphin-ring containing compounds. Protoporphyrin-IX and heme. Structure and biological importance of hemoglobin and myoglobin. Intermediates of heme: biliverdin and bilirubin. Chlorophyll.

Nucleosides, nucleotides, nucleic acids.

Vitamins.

MEDICAL PHYSICS AND STATISTICS 1st semester

Lecture (2+1 hours a week) Medical physics course requirements, training objectives, subject, structure. Importance of physics in understanding physiological mechanisms, medical diagnostics, therapy and it’s use in medical research. Introduction. Course requirements, training objectives, subject, structure. Introductory examples. Types of data. Fundamentals of mathematics related to biological phenomena. Population and sample characteristics. Definitions, examples, distribution of a sample, measures of the center and variability, and their properties. Displaying data. Scatterplot. Mechanics of the human body. Mechanics of rigid and deformable structures. Description of motion. Description of linear relationship: correlation and regression analysis. The equation of the best fitting line, the principle of least squares. Regression using transformations. Mechanical oscillations in the living organism. Fundamentals of wave theory. Doppler effect. The basics of probability theory. Experiments, events, operations with events, the concept of probability, rules of probability calculus in special cases. Distribution of variables, some important distributions (uniform, binomial, normal). Sound – ultrasound: describing the physical process, interaction of ultrasound with human tissue, medical applications. Statistical estimation, confidence interval.. The standard error of mean. The aim and steps of hypothesis testing, one-sample ttest. Eyesight, corrections. Optical instruments in medicine.

Practice/Seminar (2 hours a week) Anthropometric measurements. Fundamental aspects of measurements: derived quantities, measurement error.

Force, work and power measurement. Introduction to the BIOPAC measurement system. Data collection, data processing, illustration.

Electrophysiology I.: Electromyography. Relationship between the measured electric signal and the applied force. Linearization. Studying muscle fatigue.

86 Paired t-test, two-sample t-tests. Assumptions. F test for testing equality of variances. Thermal interaction between the human body and its environment. Temperature, its measurement, heat, heat transport. Statistical errors, the increase of Type I error, ANOVA models Principles of fluid mechanics. Models of linear and nonlinear regression. The significance of the correlation coefficient, hypothesis tests for the coefficients of regression line. Physics of biological membranes, diffusion, osmosis. Nonparametric tests using ranks. Thermodynamic aspects of transport processes. Contingency table, observed and expected frequencies, degrees of freedom, the chisquare test, assumptions. Special case: a 2x2 table. Odds ratio, relative risk. Bioelectric phenomena: interpretation of resting membrane potential, changes in membrane potential in response to stimuli, action potential. Diagnostic tests. Electricity and magnetism in biological processes and diagnostics. Survival analysis, life tables, Kaplan-Meier method. Signal, signal processing, visualization. Summary, case-studies. 2nd semester Lecture (2+1 hours a week) Introduction. Therapeutic and diagnostic procedures. Fundamentals of quantum mechanics. Atomic physics. Atomic spectra. Electromagnetic radiation. Luminescence. Radiation basics, dosimetry. Measuring dose. Absorption, scattering, reflection, interaction with matter. Spectroscopy (optical, with an outlook to general spectroscopy). Principles of LASER. Medical applications of lasers, laser – matter interaction. X-rays: general properties, their use in diagnostics. Absorption of X-radiation. Producing X-rays, interaction with living substances. Nuclear physics. Radioactivity. Nuclear radiation, dosimetry. Practical application of radioactive isotopes. Particle accelerators in the medical practice. Radiological protection. Medical imaging techniques: ultrasound, CT, MRI/NMR, PET, infrared diagnostics.

Characterising sound waves: frequency, loudness, power.

Blood pressure measurement: Korotkoff-sounds, oscillometric method. Hydrostatic pressure of blood column.

Evaluation of the blood pressure measurement results

Make up practicals

Practice/Seminar (2 hours a week) Electrophysiology II. ECG period / frequency, frequency spectrum, filtering. Unipolar and bipolar leads. Differential amplification.

Pulmonary function: flow and volume of inhaled and exhaled air (spirometry)

Measurement of the focal distance of optical lenses, visual acuity.

Electrodermal activity

Light absorption. Fundamentals of spectro-photometry.


87

Physical basis of therapeutic methods: CT image - reconstruction laser -, light -, radio -, heat – therapy, therapeutic use of electricity. Physical methods in physiological research: microscopy (optical -, scanning -, electron -) mass spectrometry Molecular and cellular diagnostics: Make up practicals sedimentation, electrophoretic methods,flow cytometry Biophysics of the senses: vision, hearing. Relationship between stimulus and sensation.. MEDICAL PHYSIOLOGY 3rd semester

* *

LECTURE (6hrs/week) Introduction. Regulation dynamics. Membrane: transport mechanisms, electrical activity.

*

Transmission of excitation.

*

Muscle physiology.

*

Fluid compartments. Physiology of the blood.

*

Heart physiology.

*

Circulation physiology.Renal physiology.

*

* *

Osmoregulation, volumen regulation. Respiration physiology.

PRACTICE (2 hrs/week)

Recording techniques. Recording devices: Methods of stimulation: thermal, chemical, electrical, types of electrodes. Studies on nervemuscle preparation (frog): video, anaesthesia, righting (turning) reflex, decapitation, lesioning of the spinal cord, studies on nerve-muscle preparation, direct and indirect stimulations, stimulus summation, complete and incomplete tetanus, rheobasis, chronaxia, recording of fatigue in the muscle. Principles of blood tests: the microscope in hematological tests, sterilization and disinfection, methods of taking blood (vein, fingertip), using and cleaning of the diluting pipettes, Bürker's chamber, Westergren's tube, centrifuges. Blood smear. Principles of bleeding time, blood clotting time, Staining index, Price-Jones's curve, partial thromboplastin time and thrombin time. Blood tests: hematocrit (micro-, macro-), determination of hemoglobin concentration (Drabkin), erythrocyte sedimentation rate by Westergren, differential count (leukocytes), osmotic resistance of red blood cells, prothrombin time, blood groups (AB0, Rh), red blood cell count, white blood cell count, thrombocyte count (Fischer-Germer), reticulocyte count. Blood tests: hematocrit (micro-, macro-), determination of hemoglobin concentration (Drabkin), erythrocyte sedimentation rate by Westergren, differential count (leukocytes), osmotic resistance of red blood cells, prothrombin time, blood groups (AB0, Rh), red blood cell count, white blood cell count, thrombocyte count (Fischer-Germer), reticulocyte count. Studies of the circulatory system I. : video, in situ registration of the activity of the heart in the frog, effects of electrical and thermal stimulations of the heart, Stannius' ligatures, summation, all or none law, Goltz reflex. Studies of the circulatory system II. Effects of ions (adrenaline, acetylcholine, atropine) on the heart, in the isolated rat heart preparation (Langendorf perfusion). The human circulatory and respiratory system: ECG, peripheral pulse, characteristics of the radial pulse, palpation over the chest, auscultation over the heart and lungs, the effects of physical exercise on circulation, spirometry, determination of inspiratory and expiratory pressures, effects of breathing on the circulation, cold pressor test, blood pressure measurement.

88 * * * * *

pH regulation. Gastrointestinal physiology. Nutrition physiology. Vitamins. Metabolism. Thermoregulation. Sport/work physiology.

4th semester

* *

*

*

*

*

*

*

* * * * *

LECTURE (4hrs/week) CNS, introduction, transmitters

PRACTICE (2 hrs/week) General information. Video (GI tract, liver). Collection of gastric juice, test meal (principle) Autonomic nervous system GI tract: The pH of the saliva. Detection of proteins in saliva. Demonstration of amylase and maltase activities in the saliva. Detection of lactic acid in gastric juice. Demonstration of the protein digesting activity of pepsin. Measurement of acidity of gastric juice. Analysis of feces: colour, smell, pH etc. Microscopic examination of the feces. Detection of blood in feces. Studies on gastric acid and bile secretion in rats. Demonstration of the movements of the small intestine according to Magnus' method. Motor system, spinal cord Urine analysis I.: Colour, smell, transparency and pH. Microscopic investigation of the urinary sediment. Specific gravity. Detection of UBG (Ehrlich's method). Detection of calcium (Sulkowitsch' test). Detection of sugar (Nylander's and Fehling's tests). Detection of protein (Heller's test, boiling test, sulphosalicylic acid test). Detection of blood (benzidine test). Detection of acetone. Detection of bile pigment. Detection of pus (principle). Rapid strip tests. Video (kidney). Physiology of the cerebral cortex, Urine analysis II.: Demonstration of the effect of ADH on urine output. EEG Dilution and concentration test in human (principle). Counting corpuscular elements in urine (Addis' method). Determination of clearance (principle). Analysis of an unknown urine sample. Receptors. Somatosensory Human reflexes. Patella-, Achilles-tendon, biceps-, triceps-, radialsystem reflex. Skin reflexes. Reaction time. Tremor. Demonstration of bloodbrain barrier in the rat. EEG. Chronically implanted EEG-electrodes in rats. Computer program (EEG). Video (Development of the motor system of a baby, EEG). Vision. Hearing Video, motor functions of intact frog. Posture and locomotion. Righting, compass- and cornea-reflex. Motor functions of the spinal frog. Spinal shock and muscular tension. Wiping-reflex. Hugging-reflex. Reciprocal innervation. Protective (flexor-) reflex. Reflex-irradiation. Stimulus summation. Analysis of the reflex-arc. Determination of reflex-time. Reflex hyperresponsiveness after strychnine. Taste, smell Sensory organs I.: Visual acuity. Correction of faults of refraction (principle). Accommodation. Mariotte's blind-spot test. The lightresponse of the pupil. Testing of colour blindness. Perimetry. Ophthalmoscopy. Dark adaptation. Purkinje-Sanson's images. Fusion frequency. Nystagmus. Detection of astigmatism (Placido's keratoscope, Javal-schiötz'-ophthalmometer). Visual evoked potentials (computer program). Endocrinology, hypophysis Sensory organs II.: Laryngoscopy, otoscopy. Acoustic acuity (drop-test, audiometry). Tests with tuning fork (examinations according to Rinne, Schwabach and Weber). Bárány's pointing test. Olphactometry. Tests of somatosensations (pressure, pain, tactile sense etc.). Video (Vision, inner ear). Pregnancy tests. Adrenal cortex. Thyroid gland Thorn's test (principle). Pancreas The effect of insulin on blood glucose level. Parath. gland Ca2+, adrenal Video (Sleep, behaviour). medulla Reproduction, male sexual. Reproduction, female sexual

Curriculum 2014/2015 * *

Emotions, limbic system Speech, hemispherical lateralization. Learning

HUNGARIAN LANGUAGE 1st semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) Introduction: general information about the language. The Hungarian alphabet, pronunciation and intonation. Greetings, notices. Getting acquainted: Who are you? Where are you from? Conjugation of the verb ‘to be’, subject form of the personal pronouns. What is where in Szeged? Asking questions. Question words, existential sentences. Definite and indefinite articles. Meeting students. The conjugation of verbs: present indefinite conjugation, singular forms. Cardinal numbers: telephone numbers and prices. Going shopping. The accusative form of nouns. Revision of grammar and vocabulary. Going to the cinema. Telling the time. Making an appointment. Plural forms of the verb (indefinite present tense). The postposition ‘elıtt’. TEST 1 A Sunday out: museum, theatre. The plural form of nouns and adjectives. Expressing possibility. The infinitive form. Buying cinema tickets. Practising the present tense indefinite conjugation. Some adverbial suffixes: -ba/-be (to, into), -ban/-ben (in) In a restaurant. Ordering a meal. Further adverbial suffixes: -hoz/-hez/-höz (to), -nál/-nél (at) General revision. TEST 2 Oral tests

2nd semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) My family:possesive suffixes, genitive structure. I have a…:Possesives+case endings. Expressing possession. What is your friend like:describing people. Calendar, dates. Revision TEST 1 Students life: review of indefinite conjugation. Transitive and intransitive verbs. Definite conjugation. Daily routine: verbal prefixes. Finding a flat: suffixes tól/tıl, hoz/hez/höz, ra/re. Compound nouns. Weather and seasons. General revision. TEST 2 Preparation for the oral exam. Oral tests

3rd semester

* * * *

PRACTICE (4 hrs/week) General revision. A weekend trip to Budapest. The comparative and superlative form of adjectives. Travelling by train. Sightseeing. Travelling abroad:revision of case endings and postpositions. Noun formation. I feel ill 'kell'+personalised infinitive. Reflexive pronouns. Health vocabulary.

89

90 * * * * * * * * * *

At the doctor's: kell, lehet, szabad, tilos. Suffix szor/szer/ször. Body parts. Revision TEST 1 Where were you in the summer: past tense conjugations. What happened? :past tense definite and indefinite. Time expressions. Revision of grammar and vocabulary. Revision of grammar and vocabulary. TEST 2 Preparation for the oral exam Oral tests

4th semester PRACTICE (4 hrs/week) * Services: possesive suffixes in the plural. At the pharmacy. * Private conversations:personal pronouns with case endings. Hat/het. * Revision of past and present tense conjugation. * Questions and question words. * Word order and complex sentences. * Grammar exercises and reading comprehension tasks. * TEST 1 * Practising role-play and picture description. * Practising role-play and picture description. * Grammar exercises and reading comprehension tasks. * Grammar exercises and reading comprehension tasks. * Words originating from the same root (kezd, kezdıdik etc.) * Revision of grammar and vocabulary. * Practising role-play and picture description. LATIN 1st semester

* * * * * * * * * * * * * *

PRACTICE (2 hrs/week) The role of the Latin language in medicine. Pronunciation. Groups of nouns - typical forms. 1st declension. Grammatical gender. Noun - adjective agreement. Cases - Possession. Praes. Imp. Act. Forms of the verb „to be”. 2nd declension. Examples from anatomy. Prepositions. The verb. Miscellaneous exercises on the covered subjects. Mid-term test. 3rd declension. Nouns. Typical endings, typical gender. 3rd declension nouns + adjectives ending in -us, -a -um. Adjectives ending in -is, -e, -ns. Adjective formation. Noun + adjective use (examples from anatomy). Cardinals, their use. Clinical and pathological diagnoses. Miscellaneous exercises on the covered subjects. Final test. Evaluation.

2nd semester

* * * * *

PRACTICE (2 hrs/week) Revision. Picking topics for weekly student presentations. 4th declension. Greek prefixes. 5th declension. Greek suffixes. Comparison of adjectives. Examples from anatomy, pathology, physiology, clinical subjects. Verbs in medicine, in medical prescription. Imperative. Greek elements in medicine.

Curriculum 2014/2015 * * * * * * * *

Miscellaneous exercises. Mid-term test. Medical prescription. Formules. Abbreviations Greek elements in medicine. Latin - Greek equivalents. Diagnoses - clinical and pathological. Miscellaneous exercises. Analysis of disease names with Greek and Latin elements. Miscellaneous exercises. Revision. Final test.

BIOCHEMICAL BASICS OF PREVENTIVE MEDICINE 4th semester

* * * * * * * * * * * * * * * * * * * * *

LECTURE (2 hrs/week) Introduction to preventive medicine (importance of nutrition, physical activity and stress in the development of „civilization diseases”) Biochemistry of oxidative stress and its importance in physiological and pathological processes (formation of free radicals and their effects) Antioxidant mechanisms (vitamins, vitaminlike substances, enzymes and their cofactors involved in antioxidant protection) Stress adaptation of the heart (early and late preconditioning) General importance of balanced nutrition (macro- and micronutrients, alimentary fibers; additives) Pathobiochemistry of atherosclerosis and possibilities of prevention Role of oxidative stress in respiratory diseases Role of free radicals and antioxidant protective mechanisms in physiological and pathological brain function Background and prevention of obesity, metabolic syndrome and diabetes mellitus Altered requirements for nutrients in physiological and pathological conditions; diets (theory and practice) Sport biochemistry: general importance of physical activity (oxidative stress and role of antioxidants; changes in blood plasma parameters) Psychological stress, oxidative stress, and importance of stress management Biochemical basics of preventive medicine in the light of the most recent medical literature (interactive seminar and test) Biochemical basics of preventive medicine in the light of the most recent medical literature (interactive seminar and test)

BIOCHEMISTRY SEMINAR 1st semester

* * * * * * * * *

LECTURE (2 hrs/week) Characterization of proteins (protein structure, folding, chaperones, and central role of heat shock proteins) Enzimology (molecular mechanism of enzyme action, regaulation of enzyme activity, enzyme classes, isoenzymes, coenzymes) Carbohydrate metabolism (alternative pathways, metabolism of galactose and fructose, patobiochemical aspects, glucuronic acid shunt) Carbohydrate metabolism (regulation of carbohydrate metabolism, regulation of blood glucose level, glucoproteins) Lipid metabolism (metabolism of phospholipids and sphyngolipids, detailed characterization of fatty acids, eiokazoids) Lipid metabolism (metabolism of cholesterol and its derivative, transport of cholesterol, cardiovascular risk factors) Amino acid metabolism (N balance in human body, specialized products derived from amino acids) Amino acid metabolism (inherited disorders affecting amino acids and their diagnostics) Nucleic acid metabolism (drugs influencing nucleotide metabolism and patobiochemical aspects)

91

92 * * * *

Consultation. Citric acid cycle (central role in the metabolism, connection to other metabolic pathways) Terminal oxidation and oxidative phosphorylation Summary of metabolism

2nd semester LECTURE (2 hrs/week) * * * * * * * * * * * * * *

General information Biochemistry of blood (pathobiochemistry of plasma proteins and biochemical background of blood coagulation) Biochemistry of blood (ion determination and blood-gas analysis) Inherited metabolic disorders Pathobiochemical aspects of connective tissue. Pathobiochemical aspects of adhesion receptors and cytoskeleton. Biochemical background of risk factors of cardiovascular diseases. Biochemistry of vision. Pathobiochemistry and diagnostics of liver. Pathobiochemistry and diagnostics of diabetes mellitus. Signaling Biochemistry of nutrition Molecular biology diagnostics Exam

BIOINORGANIC CHEMISTRY 2nd semester

*

* * * *

*

*

*

*

* * *

LECTURE (1 hr/week) Macro and micro elements. Alkali metals and their compounds. Complexes of alkali metals. Function of NaK pump. Biological role of lithium, sodium and potassium ions. Important alkaline earth metals. Calcium signal. Calcium binding proteins. Calcium transport systems. Characterization of d-transition metals. Complex formation. Chelate complexes. Role of complexes in biological systems. Iron and its compounds. Biological role of iron: heme, carrying of oxygen. Electron transport and cytochromes. Catalase, peroxidase. Metabolism of iron. Metabolism problems. Copper and its compounds. Copper-metalloenzymes and their role: cytochrome oxidase, superoxide dismutase, amine oxidases. Hemocyanin. Problems in the metabolism of copper. Zinc and its compounds. Role of zinc metalloenzymes in hydrolytic reactions. Carbonic anhydrase, carbopeptidase, alcohol dehydrogenase, alkaline phosphatase. Zinc-finger protein and their binding to DNA. Zinc-peptide complexes, zinc-insulin. Poisoning effect of cadmium and mercury. Molybdenum and its complexes, molybdenum metalloenzymes (aldehyde oxydase, xanthine oxydase and dehydrogenase). Manganese and its compounds, role of manganese in photosynthesis. Vanadium, vanadates and bone formation. Toxic effect of chromium. Cobalt and its complexes: vitamin B-12. Hydrogen and its compounds. Isotopes of hydrogen. Application of radioactive isotopes: tracing, isotope dilution analysis. Medical therapy and diagnosis: application of technetium and iodine isotopes. Iradiation therapy. Boron and its compounds. Bactericid and fungicid effects of boron. Aluminum and its compounds, medical usage. Toxic effect of aluminium ions. Lead and its compounds, toxic effect, lead poisoning and its therapy. Tin and its compounds. Carbon. Carbon monoxide, carbon dioxide, carbonic acid, carbonates. Hydrogen cyanide, cyanides. Silicon and its compounds. Effect of silicates in the development of diseases, silicosis. Application of silicates in medicine. Halogens and their compounds. Biological role of fluoride ion, fluoroapatite. Biological role of chloride ions, chloride transport. Medical usage of iodine and its compounds. Nitrogen and its compounds. Nitrogen oxides: Medical usage of dinitrogen monoxide in medicine, biological role of nitrogen monoxide. Nitric and nitrous acids. Nitrates, nitrites, detection, toxic effect. Phosphorus and its poisoning effect. Phosphoric acids. The role of high-energy phosphate bonds in the


93

energy production of cells. Oxygen and ozone. Oxides, peroxides. Reactive particles formed from oxygen. Oxygen activating enzymes, oxygenases and oxydases. Formation, toxic effect and elimination of oxygen radicals in biological systems. Oxygen poisoning Sulphur. Hydrogen sulphide and sulphides. Sulphur dioxide and trioxide, sulphurous and sulphuric acids, sulphites and sulphates. Selenium and its compounds. Selenium as an essential micro element.

*

*

CARDIAC ELECTROPHYSIOLOGY AS A BASIC PROPERTY OF CARDIAC FUNCTION 4th and 8th semester

* * * * * * * * * * * * * *

LECTURE AND PRACTICE (2 hrs/week) Introduction. Basic principles of electrophysiology, the impulse propagation in the heart I. Basic principles of electrophysiology, the impulse propagation in the heart II. The action potential of myocytes and the ionic channels determining the action potential I. The action potential of myocytes and the ionic channels determining the action potential II. Methods and techniques in cardiac electrophysiology. Electro-mechanical coupling in the heart I. Genetic background of ion-channel disturbances in the heart. Electro-mechanical coupling in the heart II. The mechanism of developing cardiac arrhythmias Electrophysiological changes after the disturbances in blood supply to the myocardium. Experimental methods and clinical relevance to investigate cardiac arrhythmias. Investigational techniques in cardiac cellular electrophysiology Practical and consultation

CYTOMORPHOLOGY AND MICROTECHNICS 1st semester, 3rd and 5th semester LECTURE (2 hrs/week) * Evolution of cellular organisms. General morphology of the eukaryotic cell: size, shape. Research methods for structural cell biology. * Intracellular compartmentalization. Structure of the cell membrane. The endomembranes. Membrane dynamics (membrane fusion and fission). * Membrane modifications: cell surface modification (microvilli, stereocilia, cilia), coupling structures (belt-, spot-, hemidesmosome), impermeable junction (tight junction), communication junctions (gap junction, chemical synapse). * Structure and functions of the extracellular matrix. The lamina basalis. Cell adhesion molecules. * Structure and functions of the cytoskeleton. General characteristics of cytoskeletal proteins. Actin filaments/microfilaments. Microtubules and intermedier filaments. * Light- and electron microscopic structure of the cell nucleus and nucleolus. Organization of the chromatin. Chromosomes. * The cell cycle. Growth and division of the cell. Mitotic and meiotic cell divisions. * The endomembranes: endoplasmic reticular systems, Golgi complex. Targeted intracellular transport of ptoteins. The vesicular transport and secretion * Transport across membranes. Internalization of macromolecules and viruses. Phagocytosis. Receptor-indiced endocytosis, exocytosis, transcytosis. The lysosomes. * Mitochondria: general characteristics and types.

* * *

Cyto- and histotechnics I. Nuclear / chromatin staining methods. Light- and electron microscopic enzyme histochemical methods. Cyto- and histotechnics II. Light- and electron microscopic immunocytochemical and –histochemical methods. Scanning electron microscopic techniques (freeze-etching, freeze-fracturing, etc.).

INTRODUCTION TO ANALYTICAL CHEMISTRY

94 1st semester

* * * * * * * * * * * * * *

LECTURE (1 hr/week) Definition of quantitative and qualitative analysis. Application of analytical chemistry: environment protection, clinical diagnosis, pharmacology, bioanalysis. SI Units, prefixes and base units. Types of concentration of solutions. Methods of analytical error calculation. Inaccuracy of measurement. Sources of inaccuracy. Systematic error. Minimizing systematic error. Reduction of accidental error. Characteristics of analytical methods: accuracy, precision, average, median. Standard deviation. Distribution of the result. Accuracy of measurement. Selectivity. Factors that influence selectivity. Analytical interference. Example. Prediction and avoidance of analytical interference. Sensitivity of analytical methods. Definition. Sensitivity of different analytical methods. Choosing of the appropriate analytical method. Measuring of low concentrations. Steps of quantitative analysis. Sampling. Gravimetry. Definition, steps, example. Advantages and drawbacks of gravimetric analysis. Volumetric analysis (titrimetry). Definition. Possible reactions, examples. Indication of the end-point of titration. Standardized solution. Types of titration. Acid-base titration. Measuring of pH during titration. Titration curve, equivalence point. Titration of weak acids by strong bases. Titration of polyprotic acids. Acid-base indicators. Indicator error. Complexometry. Formation of a complex. Stability of complexes. Metal indicators. Titration curve. Example. Redox titration. Types of redox titration: permanganometry, chromatometry, cerimetry, bromatometry, iodometry. Application. Precipitate formation titrations. Argentometry. Application.

INTRODUCTION TO INFORMATICS 1st semester LECTURE (1 hr/week) Why do we learn and teach medical informatics? The information system of the health. History of computing hardware. (From the mechanical devices to supercomputers). Software. The operating system, viruses. Computer networks, internet, data protection. Development and integration of software application. Data presentation, documents handling, spreadsheets, data analysis and reports. Internet browsers, search engines, metadata, web documents, Web 2.0 Virtual reality. Telemedicine. Integrated IT support of scientific research. Data and information in health care. Health care data types: text, signs, images, sounds, videos, codes, medical code systems. Integrated hospital information systems. (Database and standards). Digital medical image communication systems and standards (PACS, DICOM).

PRACTICE (2 hrs/week) Hardware and software environment (login, rights, sharing resources) of the practice. ETR CooSpace. Creating presentation: IT in health care. Examination of medical data with spreadsheets (validation, sorting, filtering). Evaluation of medical data with spreadsheets (calculations). Evaluation of health information (functions, sub-total tables). Health data presentation (tables, charts, graphs, images).

1st practical test Literature reference; well-known databases and queries. Documents Formatting large documents templates and styles.

Advances document editing, embedding tables, graphs and images.

Digital medical images, basic image processing.

2nd practical test

New trends in medical informatics. Advanced

Conclusion remarks and discussion of practical marks


95

systems INTRODUCTION TO MEDICINE 1st semester

* * * * * * * * * * * * * *

LECTURE/PRACTICE (1 hr/week)/(1 hr/week) Health Philosophy and Behavioral Medicine I. Modern concept of health and disease Health Philosophy and Behavioral Medicine II. What influences health? The development of disease: Causal models Health Philosophy and Behavioral Medicine III. Stress, coping, culture and lifestyle Preventive Medicine and Public Health I. Community diagnosis. Describing health problems Preventive Medicine and Public Health II. Analyzing health problems. Risk perception and risk communication Preventive Medicine and Public Health III. Basic theories of prevention and health education. The role of screening in prevention History of medicine I. Earliest medicine, antique times History of medicine II. Medicine in Middle Ages, Renaissance, Enlightenment History of medicine III. Science and technology in the19th-20th centuries Medical Ethics I. The Hippocratic oath Medical Ethics II. Ethics, morality and ethical theories Medical Ethics III. Basic principles of bioethics WRITTEN TEST EXAM

INTRODUCTION TO PSYCHOLOGY, BASICS OF NURSING 2nd semester LECTURE (1 hr/week) * General prelude, the attitude, point of view of the curse, what is psychology, the relation between psychology and medicine. The necessity and traits of self-evaluation (selfimage, assertive attitude, games people play, and it’s solution) * Block in basic and biological elements of psychology (Sensation and perception). The psychology of social interactions (Basic elements of perception of people, schemas, stereotypes, attributions, the point of view of individual psychology) * The psychology of social interactions (Basic elements of social behavior – the effect of people’s presence on human achievement, human groups and roles, the human mass’s symptom) *The psychology of social interactions (submission, diffusion of responsibility, conformity to the great mass, the effect of minority on the majority) * General psychology (attention, memory, imagination, human consciousness, thinking) * Motivation (, human needs, sexual-, human arousal) * Human values (The base of values - cognition, exploration -, self-respect and respecting people), The born-out syndrome (how to protect our mental health and harmony) * Emotions (the evolution of them, theories of

COMMUNICATION SKILLS (PRACTICE) (2 hrs/week) * Introduction, technical details * Basic elements of communication * Factors which disturb the communicational process I. * Factors which disturb the communicational process II. * Verbal communication I. * Verbal communication II. * Factors which disturb the communicational process III. * Nonverbal communication I. * Nonverbal communication II. * Cultural presentation I. * Cultural presentation II. *Discussion

96 their functioning, the mechanism of facial feedback, and it’s practical utility) * The personality (definitions, theories, the role of nature and nurture) * The psychology of human development (The importance, sections, approaches of it) * The mechanism of human behavior, the possibilities to take effect on it. Basic element of learning processes (Respondent or classical conditioning, Instrumental conditioning, complex –observational, and cognitivebehavioral – learning, and it’s practical utility) * Summary of practical utilities of psychology – Questions and answers MEDICAL ANTHROPOLOGY 4th semester

* *

PRACTICE (1 hr/week) Introduction to cultural and medical anthropology Cultural anthropology of anatomy and physiology (lay beliefs)

* * * * *

Medical anthropology of stress and stress-related disease Medical anthropology of pain and nutrition Medical anthropology of sexuality and gynecology Cultural aspects of health care Medical anthropology of death and dying

MEDICAL SOCIOLOGY 3rd semester

* * * * * * * * * * * * * *

PRACTICE (2 hrs/week) What is sociology? Theories and perspectives in sociology. Role of behavioural sciences and medical sociology in medical education. Development, division, research fields of medical sociology. The medical profession. Professional socialisation among medical students. Gender differences among medical students in their professional socialisation. Role conflicts between family and professional roles. Doctor-patient interaction, models of the doctor-patient relationship. Parsons' concept of the sick- and doctor roles. Illness behaviour. Going to the doctor. Sociology of disability. Labelling and stigma. Illness as deviance, primary, secondary deviance. Deviance behaviours. Theories of deviance: biological, physical, psychological, sociological theories. Stratification and class. Social mobility. Social causes of illness, social patterns of illness (social aetiology of disease). Global inequality. Race, etnicity and migration. Social inequalities and health. Poverty, social exclusion and welfare. Families and intimate relationships. The life-course. Practice of medical sociological research methods. Strategy and research methods of medical sociology.

MOLECULAR CYTOLOGY AND HISTOLOGY 1st semester LECTURE (2 hrs/week)

Curriculum 2014/2015 * * * * * * * * *

*

Connective tissue fibers: types, synthesis, occurrence in various organs and in the basement membrane. Staining of connective tissue fibers for routine histology and pathology. Muscle tissue: light- and electron-microscopical properties, and molecular composition. Endocrine function of muscle tissue. Blood - and lymphatic vessels: light- and electron-microscopical properties. Ultrastructure of capillaries in various organs. The kidney, the testis and the ovarium: light- and electron-microscopical properties. Development of the ovarian follicles. Ultrastructure of spermatozoon. Formed elements of blood: light- and electron-microscopical properties. Haemopoiesis. Types of lymphocytes. Antigen-presenting cells. Electron-microscopical features of lymphoid organs. The teeth, the major salivary glands and the tounge: functional histology and electron-microscopical features. Innervation of salivary glands. The stomach and the intestines: light- and electron-microscopical properties, and microcirculation. Immune system of the alimentary tract. The liver, the bile system and the pancreas: functional histology and electron-microscopical features. Microcirculation and lymphatics of the liver. Innervation of the liver and the pancreas. The respiratory system: functional histology and electron-microscopical features. The blood-air barrier. Tissue-specific macrophages in the lung. Innervation, blood circulation and lymphatic drainage of the bronchial tree and the pleura. The endocrine system: functional histology and electron-microscopical features. Modulations of the hormone release. Neurosecretion.

MOLECULAR DEVELOPMENTAL BIOLOGY 4th semester

* * * * * * * * * * * * * *

LECTURE (2 hrs/week) The molecular developmental aspect of medical biology General mechanisms of embryonic development The formation of body pattern (polarity, segment polarity, body domains) and appendix development Seminary (lectures 1-3) Cell movement and body formation in vertebrates, neural development The formation of the epiderm and its renewal from stem cells. Sensory epithel, airway system, gut and liver development. Seminary (lectures 5,6) Blood vesels and endothel cells, multipotent stem cells, blood cell renewal. Fibroblasts and their transformations. The movement and muscle types. The origin a nd potency of stem cells. Seminary (lecture 8) The cancer as a microevolutionary process. Tumor formation nand its molecular background Seminary (lecture 10,11) The molecular biology of nutrition and life span Seminary (lecture 13)

NEUROCYTOLOGY 2nd semester

* * * * * * *

LECTURE (2 hrs/week) History: discovery of the neuron and glial cells, neuron theory, the discovery of synapses and synaptic transmission Immunohistochemistry, in situ hybridization: pheno- and genotyping of neurons and glial cells The cytology of glial cells: astrocytes, oligodendrocyte, microglia, ependyma and choroid epithelium, Schwann cells, myelin sheath The morphology of the blood-brain barrier: ultrastructure of cerebral vessels, the regulation of cerebral circulation The structure of the neuron: axontransport, dendrite-transport, neurosecretion and neuroresorption Basic neuropathological processes: chromatolysis, Wallerian degeneration, hypoxia, neuronal damage The ultrastructure and types of synapses: chemical and electric synapses, types of vesicle, transmitters and receptors, the mechanism of the exocytotis of the synaptic vesicles

97

98 * * * * *

Glutamate as a neurotransmitter: immunocytochemical identification, types of receptors, molecular structure and distribution The cholinergic system:cholinergic nuclei, neurotransmission, receptors, pathology, Alzheimer’s disease Neuroimmunology Functional neuroradiology Neurocytology of the peripheral nervous system: distribution and cytochemical anatomy of the nerve and glial cells in the peripheral nervous system

ANIMAL EXPERIMENTS IN MEDICINE 3rd, 4th, 5th, 6th, 7th, 8th, 9th or 10th semester

* * * * * * * * * * * * * *

LECTURE (2 hrs/week for 11 weeks) Introduction, general information. The theoretical background, history and significance of animal experiments in research. Animal models in biomedical research Ethical aspects and legal regulation of animal experiments Keeping, care, handling and transport of experimental animals. Biology, microbiological quality and diseases of the most frequently used laboratory mammals General and local anesthesia, analgesia. Principles of invasive and surgical interventions, postoperative care. Euthanasia Planning and evaluation of experiments. Processing and analysis of experimental data. Statistical methods. Publication of results. Basic experimental techniques: Methods and animal models of circulation research Methods and animal models of respiration research. Methods and animal models of gastrointestinal research Methods and animal models of microcirculation research Methods and animal models of neurobiological research Research methods of pharmacodynamics. Research methods and animal models of the reproductive system Methods and animal models of dermatological research. Biocompatibility examinations. Alternative methods for the replacement of animal experiments. In vitro techniques and models Outbred, inbred and genetically modified animals, cloning. Animal models in immunobiology Written test exam

BODY DEVELOPMENT AND DISEASES - A MOLECULAR BIOLOGICAL BACKGROUND 4th semester

* * * * * * * * * * * * * * *

LECTURE (2 hrs/week) The general mechanisms of animal development. Siamese twins, embryo deformities The formation of body pattern (polarity, segment polarity, homeotic genes), organ formation and appendages. Molecular base of appendage abnormalities Cell movements and body formation of vertebrates. The formation of body axis (situs inversus totalis). The neural development. The axonal growth cone, formation of the visual and auditory map, formation and processing of the synapse. The formation of the epidermis and its renewal from stem cells. Definition of stem cells, types of stem cells, use for therapies. The sensory epithelial development. Molecular evidence for renewal of connections between olfactory neurons and the bulbus. The characteristics of renewal of auditory neurons and retinal neurons. The airways and the gut development. The mucociliary escalator and its connection with situs inversus. The renewal of intestine epithelial layer. The connection between the size of the liver and the whole body. Blood vessels and endothelial cells, the molecular drive of angiogenesis, VHL syndrome and hemangioblastoma. Renewal by multipotent stem cells: blood cell formation. Pathological migration of crista neuralis cells. Genesis, modulation and regeneration of skeletal muscle. Muscle size and quality, myopathies with functional defects, secondary muscle defects. Fibroblasts and their transformations: the connective-tissue cell family. Leptins and obesity, bone abnormalities, achondroplasia. Stem-cell origin and engineering, the main questions of stem cell therapy, the special renewal of the heart and brain. Cancer as a micro evolutionary process, features making cancer diagnosis problematic. The molecular base of cancer formation, the character of tumour cell formation, the definition of tumour, the contradictive nature of tumour stem cell. Nutrition and life span, the rules of proper nutrition, the likely genetic background of metabolic syndrome,


99

genes influencing life span. MATHEMATICAL AND STATISTICAL MODELLING IN MEDICINE 4th semester LECTURE (1 hr/week) * Elementary mathematical functions (The logarithm and exponential functions). Definitions and graphs. Geometric meaning of the derivative and definite integral. * Discrete (Poisson–) and continuous ( exponential, Weibull–, normal and t-) distributions * Ratios, proportions and rates in epidemiology * Conditional probability, testing proportions: the relative difference * One- and Two-way ANOVA * Repeated measurement ANOVA * Nonparametric ANOVA. Kruskall-Wallis, Jonckheere-Terpstra and Nemenyi tests * Linear-by-linear method. Kendall tau statistic. Logrank test * Logistic and Poisson regression models (ROC curves) * Harmonic trend andseasonality (Edward and Walter-Elwood test, logistic regression and Cosinor method) * Area under curve methods * Non-linear regression models (Michaelis–Menten kinetics, RIA, Scatchard plots) * Internal and external quality control methods * Decision and cost-effectiveness analysis with probabilities. MOLECULAR MEDICINE 5th semester

* * * * * * * * *

PRACTICE (1 hr/week) Elementary mathematical functions (The logarithm and exponential functions). Definitions and graphs. Geometric meaning of the derivative and definite integral. Discrete (Poisson–) and continuous ( exponential, Weibull–, normal and t-) distributions Ratios, proportions and rates in epidemiology Conditional probability, testing proportions: the relative difference One- and Two-way ANOVA Repeated measurement ANOVA Nonparametric ANOVA. Kruskall-Wallis, JonckheereTerpstra and Nemenyi tests Linear-by-linear method. Kendall tau statistic. Logrank test Logistic and Poisson regression models (ROC curves) Harmonic trend andseasonality (Edward and WalterElwood test, logistic regression and Cosinor method) Area under curve methods Non-linear regression models (Michaelis–Menten kinetics, RIA, Scatchard plots) Internal and external quality control methods Exam

LECTURE (1 hr/week) Molecular genetic and cell biology methods in diagnosis and therapy. Diagnostic methods based on immunological techniques (RIA, ELISA, Western blot analysis, immunocytology, citotoxicity tests, etc.). Diagnostic methods beased on nucleic acid hybridization (Northern and Southern analysis, in situ hybidization, DNA chip technology, etc.). Diagnostic methods based on specific endonuclease activity (fragment length polymorphism, pedigree analysis, etc.). Gene sequencing and analysis, genomic and proteomic techniques. Cell and tissue culture methods. Antisense pharmacology. RNA interference/silencing. Small interfering RNAs. Molecular chaperons. Gene therapy, viral vectors, DNA-liposome complexes. Molecular markers in human disorders. Biomarkers for neurological and psychiatric disorders. Molecular interactions between pathogens and host.

MICROBIOLOGY I. 4th semester LECTURE (3hrs/week) * Introduction to microbiology. Characterization and classification of bacteria Structure of bacteria. Growth and nutrition of bacteria.

PRACTICE (2 hrs/weeks) Introduction to microbiology. Laboratory Safety. Aspetic techniques- Wet-mount preparation.

100 *

* * * * *

* * * * *

* *

General Characteristics of viruses, viral replication, antiviral therapy Structure of viruses and classification Herpesviriade Papilloma and polyoma viruses Poxviridae, Rhabdoviridae Orthomyxoviridae, Paramyxoviridae Togaviridae, adenoviridae Retroviridae Picornaviridae HIV Reoviridae, Astroviridae, Coronaviridae „Slow” viruses. Parvoviridae, Bunyaviridae Hepatitis viruses, Flaviviridae Arenaviridae, Filoviridae Oncoviruses Growth and nutrition of bacteria Mivrobial genetics Immune response against pathogens Pathogenesis of bacterial infection Immune response against pathogens Antimicrobial chemotherapy I., II. Antimicrobial chemotherapy III. Microbial antigens

Preparatio of bacterial smear. Simple and Gram staining. Ziehl-Neelsen, Schaffer-Fulton and Neisser staining Methods of sterilization. Sterility testing Methods for counting bacteria. Methods for disinfection Serological reactions I. (precipitation, CFT) Serological reactions II. Agglutination, ELISA. Laboratory methods for detection of cellular immunity MTO Bacteriophages, Molecular methods Virology I. Cultivation of viruses Signs of Viral replication Virology II. Quantification of viruses Virus Virology III. HAG, ELISA, IF Neutralization test Antimicrobial susceptibility testing Consultation

Immunology I. 4th semester LECTURE (2hrs/week) * Introduction to immunology. Basic principles * Phagocytic cells, phagocytosis. Innate immunity * The structure and activation of the complement system * Ontogeny of B cells. Antigen recognition * B cell activation. Humoral immune response * Ontogeny of T cells. Antigen recognition * Major histocompatibility complex (MHC) * Antigen processing * Cytokines I. * Cytokines II. * Hypersensitivity reactions * Tumonrimmunity * Transplantation immunity * Tolerance, autoimmunity


101 SYLLABUSES PRE-CLINICAL MODULE - MEDICINE

CLINICAL DIAGNOSTICS I. – INTERNAL MEDICINE 5th semester

* * *

LECTURE Basics of Haematology (2 hrs/week) Case history, documentation Inspection, palpation Percussion, auscultation

*

Fever, pulse, blood pressure

*

Heart sounds

* * * *

Electrocardiography Electrocardiography Echocardiography Modern cardiological investigative methods Abdominal sonography Modern gastroenterological investigative methods Physical examination in ophthalmology Physical examination in neurology Consultation

* * * * *

PRACTICE (2 hrs/week) General introduction and guide to the practicals in internal medicine Documentation, taking history Elements of physical examination: practical aspects of inspection, palpation Elements of physical examination: practical aspects of percussio and auscultation Elements of physical examination: feeling pulse, checking blood pressure, taking temperature Listening to the heart and chest Basic aspects of electrocardiography. Developing skills in PE Practical electrocardiography. Developing skills in PE Practical electrocardiography. Developing skills in PE Practical echocardiography. Developing skills in PE Practical echocardiography. Developing skills in PE Abdominal sonography Physical examination in neurology. Developing skills in PE Consultation

CLINICAL DIAGNOSTICS II. – SURGERY 6th semester Lecture * The origins and development of surgery * * * * * * * * * * * * * *

Practice/Seminar Demonstration and investigation of surgical patients Observation and documentation of surgical “ patients The shock. Basic mechanism and clinical “ profile The circulatory shock “ The basis of fluid and electrolyte therapy in “ surgical patients Blood transfusion “ Bleeding and haemostasis “ The significance and role of asepsis and “ antisepsis in the practice of surgery Surgical infections. Modern antibiotic “ treatment Types of wounds and the basic principles of “ wound healing Perioperative complications “ Parenteral feeding “ Surgical oncology “ The possibilities and practice of organ “ transplantation Video demonstration of surgical procedures “

102 *

Test

ETHICS IN MEDICINE 6th semester

* * * * * * * * * * * * * *

LECTURE/PRACTICE (1 hr/week)/(2 hrs/week) Introduction: Basic Moral Concepts. Introduction to Medical Etics. Laws and Morals Basic Ethical Theories, Principles of Bioethics. Informed Consent Moral dilemmas in reproductive medicine. Family planning Reproductive medicine (cont.) Moral aspects of pediatrics Ethical aspects of medical genetics Surgery. Pain. Transplantation from living donors Euthanasia – a non –medical approach AIDS Cloning Research on human subjects. Patients’ rights and health care system Consultation

INTERNAL MEDICINE I. 6th semester

*

LECTURE (4 hrs/week) Esohpageal disorders

*

Peptic ulcer disease

* *

*

*

*

*

*

*

PRACTICE (2 hrs/week) Problem oriented evaluation of the symptoms of patients with esophageal disorders Practical aspects of the functional evaluation of patients with esophageal disorders (esophageal manometry, 24 h pH-metry, evaluation of the biliary reflux)

Functional dyspepsia Gastrointestinal hormones Upper gastrointestinal endoscopy Gastric Cancer Chronic hepatitis Symptomatic evaluation of the liver patient. Cirrhosis of the liver I. Problem oriented laboratory investigation of the liver patient. (etiology, symptoms) Cirrhosis of the liver II Symptoms of biliary obstruction, investigative methods for patients (complications, therapeutical with biliary obstruction (symptoms, biochemistry, ultrasonography, options) ERCP) Diseases of the biliary system I Diseases of the biliary system Symptoms of patients with acute pancreatitis II Acute pancreatitis Diagnostic work up of patients with acute pancreatitis Chronic pancreatitis Diagnostic work up of patients with chronic pancreatitis and pancreatic cancer Pancreatic cancer Pathomechanisms of Diagnostic work up of patients with CU and Crohn’s disease. Inflammatory Bowel Disease Crohn’s disease and Ulcerative Colitis Tumors of the large intestine Early identification of patients with colorectal cancer. Diagnostic methods. Malabsorption syndrome Irritable Bowel Syndrome Symptoms of malabsorption, maldigestion, Diagnostic workup: Hydrogen, c13 urea and starch breath tests Diabetes mellitus (etiology,

Curriculum 2014/2015 *

* *

*

classification) Complications of diabetes mellitus Therapy of diabetes mellitus Dyslipoproteinemias Hyperuricemia, gout Introduction to clinical immunology Rheumatoid arthritis SLE, Dermatomyosistis, Sjögren’s disease, MCTD Consultation

103 Practical aspects of the diagnosis and therapy of patients with diabetes mellitus; the patient education. Practical aspects of insulin therapy. Treatment of dyslipoproteinemias Physical examination of patients with rheumatoid diseases

Consultation

MEDICAL PSYCHOLOGY I. 6th semester

*

*

LECTURE/PRACTICE (1 hr/week)/(1 hr/week) Lecture: 1. Introduction: Medical psychology and border areas 2. The psychological process of becoming ill 3. Stress, in the light of evolution 4. Coping with stress and illness 5. Patients’ representations and beliefs about illness 6. The role of personality in the changes of health status 7. The influences of gender and age on health behaviors 8. Psychological aspects and management of pain 9. Chronic illness and social support 10. Hospitalization 11. The prevention and management of burnout among health professionals 12. Adherence in the patient–physician relationship Practice: 1. Patient-centered medicine, Biopsychosocial approach to illness 2. Understanding the Whole Person 3. Skill lab practice 4. Enhancing the Patient-Doctor Relationship, CLASS modell 5. Finding Common Grund 6. Being realistic, Burnout prevention

MICROBIOLOGY AND IMMUNOLOGY 5th semester

*

* * *

*

LECTURE ( 3 hrs/week) Introduction to microbiology. Characterization and classification of bacteria. Structure of bacteria. Growth and nutrition of bacteria. Introduction to immunology. Basic Principles. Ontogeny of T cells. Antigen recognition. Major histocompatibility complex (MHC) Ontogeny of B cells. Antigen recognition. B cell activation. Humoral immune response Antigen processing. MHC I, MHC II.

Phagocytic cells, phagocytosis. Innate immunity. The structure and the activation of the complement system.

PRACTICE ( 2 hrs/week) Introduction to microbiology. Laboratory safety. Aseptic techniques. Wet-mount preparation Preparation of bacterial smear. Simple and Gaim staining. Ziehl-Neelsen, Schaffer-Fulton and Neisser staining Culture media. Preparation of blood agar. Methods of sterilization. Sterility Testing Colony Morphology Handling bacterial cultures

104 * * * *

Hypersensitivity reactions

(inoculation and plating). Biochemical diagnostic tests.

Microbiology antigens.

Anaerobic cultivation.

Transplantation and immunity. Tolerance, autoimmunity. Immune response against pathogens Tummorimunity. Cytokines I. Cytokines II. Adhesion molecules. Pathogenesis of bacterial infection

Methods for counting bacteria. Methods for disinfection. MTO

Staphylococcus.

Serological reactions II. Laboratory methods for detection of cellural immunity Antimicrobial suscepibility testing. Staphylococcus. Streptococcus, AST.

Serological reactions I. (Precipitation, CFT). Agglutination, ELISA

*

* * * *

Antimicrobial chemotherapy I. Antimicrobial chemotherapy II. Streptococcus. Neisseria. E.coli. Shigella, Proteus Microbioal genetics Consultation

Neisseria, E.coli Consultation

6th semester

* * * * * * *

*

* * * *

* * *

LECTURE (3 hrs/week) Brucella. Listeria Yersinia. Francisella. Human pathogenic Salmonellae Vibrio cholerae. Campylobacter. Helicobacter. Burkholderia, Pseudomonas Anaerobic bacteria. Corynebacterium Mycobacterium, Legionella Bordetella, Haemophilus Treponema, Leptospira, Borrelia Bacillus Mycoplasma, Chlamydia. Rickettsia.

PRACTICE (2 hrs/week) Safety rules, Yersinina, Salmonellae, Shigellae Pseudomonas, Camplyobacter, Heliobacter Listeria, Bacillus

General characteristics of viruses, viral replication, antiviral chemotherapy. Structure of viruses and classification Herpesviridae Papilloma and plyoma viruses Orthomyxoviridae, Paramyxoviridae Togaviridae, adenoviridae Retroviridae, HIV Poxviridae, Rhabdoviridae Hepatitis viruses, Flaviviridae Slow viruses.

Bacteriophages. Molecular methods

Vaccination

Human pathogenic protozoa. Picornaviridae Human pathogenic helminthes.

Bunyaviridae, Filoviridae, Arenaviridae, Parvoviridae Protozoa, helminthes.

Important human pathogenic fungi. Reoviridae, Astroviridae, Coronaviridae

Mycology

Mycobacterium, Haemophilus Corynebacterium, Bordetella Bacteroides. Clostridium. Mycoplasma. Leptospira.

Clinical bacteriology

Virology I. Cultivation of viruses Signs of Viral Replication Virology II. Quantification of viruses Virus serology (HAG, ELISA, IF) Neutralization test


105

PATHOLOGY 5th semester

*

*

* *

* *

*

*

*

*

* * * *

LECTURE (3 hrs/week) Pathology of cellular injury and death (necrosis, apoptosis, degenerations). Cellular adaptations of growth and differentiation (hyperplasia, hypertrophy, atrophy, metaplasia). Calcification. Oedema, hyperaemia, congestion. Haemorrhage. Disseminated intravascular coagulation. Thrombosis. Embolism. Shock. Consequences of vascular occlusion. Infarction. Pathology of inflammation I. Pathology of inflammation II. Pathology of inflammation III. Pathology of inflammation IV. Tissue repair. Wound healing. Immunopathology I. Immunopathology II. Immunopathology III. Pathology of transplant rejection. Neoplasia I. Neoplasia II. Carcinogenesis. Amyloidosis. Cystic fibrosis. Pathology of bed rest. Pathology of alcohol abuse. Pathology of smoking. Diabetes. Pathology of obesity.

SEMINAR (1 hour/week) Cellular injury and death Cellular adaptations of growth and differentiation. Oedema, hyperaemia, congestion. Haemorrhage.

PRACTICE (2 hrs/week) Histolopathology of cellular injury and death/Autopsy

Thrombosis. Embolism. Shock. Autopsy/Histolopathology of Consequences of vascular occlusion. cellular injury and death/ Infarction.

Pathology of inflammation Pathology of inflammation

Immunopathology Immunopathology

Neoplasia.

Carcinogenesis. Pathology of alcohol abuse. Pathology of smoking. Diseases of the blood vessels I. Diabetes. Pathology of obesity. Diseases of the blood vessels Diseases of the blood vessels II. Diseases of the heart I. Diseases of the heart II. Diseases of the heart Essential hypertension. Nephropathology I. Nephropathology II. Diseases of the heart Nephropathology III. Nephropathology IV. Nephropathology Diseases of the lung I. Diseases of the lung. II. Diseases of the lung Diseases of the lung III. Oral pathology Gastrointestinal pathology Gastrointestinal pathology

Histopathology of degeneration/Autopsy Autopsy/Histopathology of degeneration Histopathology of degeneration/Autopsy Autopsy/Histopathology of degeneration

Histopathology of circulation disorders/Autopsy

Autopsy/Histopathology of circulation disorders

Autopsy/Oncohistopathology

Oncohistopathology/Autopsy

Autopsy/Repetition Repetition/Autopsy Autopsy/Repetition Repetition/Autopsy

6th semester

*

LECTURE (2 hrs/week) Gastrointestinal pathology.

SEMINAR (1 hr/week) Gastrointestinal pathology.

PRACTICE (3 hrs/week) Histopathology of the

106 cardiovascular system/Autopsy Histopathology of the respiratory tract/Autopsy Histopathology of the gastrointestinal system/Autopsy Histopathology of the liver and pancreas/Autopsy

*

Pathology of the liver.

Pathology of the liver.

*

*

Pathology of the biliary tract and pancreas. Pathology of soft tissue tumours. Pathology of the bones, joints and muscles. Endocrine pathology I.

Pathology of the biliary tract and pancreas. Pathology of soft tissue tumours. Pathology of the bones, joints and muscles. Endocrine pathology

*

Endocrine pathology II.

Endocrine pathology

*

Pathology of female genital system

*

Pathology of female genital system I. Pathology of female genital system II. Breast pathology. Neuropathology I.

Pathology of female genital system. Breast pathology. Neuropathology

*

Neuropathology II.

Neuropathology

*

Immune pathology

Immune pathology.

*

Pathology of male genital system. Haematopathology I. Haematopathology II.

Pathology of male genital system.

Haematohistopathology/ Autopsy Histopathology of the urogenital tract/Autopsy Histopathology of the female genital tract/Autopsy Histopathology of the breast/Autopsy Endocrine histopathology/Autopsy Histopathology of the bones, joints and muscles/Autopsy Histopathology of the nervous system/Autopsy Repetition/Autopsy

Haematopathology Haematopathology

Repetition/Autopsy Repetition/Autopsy

*

*

* *

PATHOPHYSIOLOGY 5th semester LECTURE (3 hrs/week)

PRACTICE/SEMINAR (2 hrs/week)

*

Introduction to Pathophysiology; Basics of ECG

Safety regulations. Review of physiologic background of circulation. Registration of ECG Determination of spirometric parameters.

*

Inflammation I.: Definition, causes and forms of inflammation. Mediators of acute inflammation.

Review of physiologic background of normal ECG. Registration and analysis of ECG Determination of spirometric parameters. (Lecture topic of the 1st week).

*

Inflammation II.: Cellular elements of acute inflammation. Regulation and outcome of acute inflammation.

Seminar: Inflammation I. (Lecture topic of the 2nd week).

*

Inflammation III.: Chronic inflammation. Local and generalized reactions of inflammation: fever, inflammatory pain.

Seminar: Inflammation II. (Lecture topic of the 3rd week).

*

Pathophysiology of leukocytes I.: Immunology I.: In vivo allergic reactions, autoimmunity, immunodeficiencies, oncogenesis. Arrhythmia I.: Development, mechanisms and classification of arrhythmias. Premature beats.

Seminar: Inflammation III. (Lecture topic of the 4th week).

*

Endocrinology I.: Diseases of hypothalamus, adenohypophysis, thyroid, and adrenal (cortex and medulla) glands.

Seminar: Pathophysiology of leukocytes I.: Immunology Arrhythmias I.(Lecture topic of


107 the 5th week)

*

Endocrinology II.: Male and female reproductive endocrinology. Diseases of neurohypophysis and parathyroid glands. Hypo- and hypercalcemias. Arrhythmia II.: Bradyarrhythmias and blocks.

Seminar: Endocrinology I. (Lecture topic of the 6th week).

*

Starvation and obesity. Diabetes mellitus I: definition, diagnosis and classification.

Seminar: Endocrinology II. Arrhythmias II. (Lecture topic of the 7th week).

*

Diabetes mellitus II: Type 1 and 2 diabetes mellitus pathogenesis and consequences. Hypoglycemia. Arrhythmia III.: Tachyarrhythmias.

Seminar: Starvation, obesity Diabetes mellitus (Lecture topic of the 8thweek).

*

Cardiovascular system I.: Pathophysiology of plasma lipoprotein metabolism. Atherosclerosis (development and consequences).

Seminar: Diabetes mellitus, hypoglycemia. Arrhythmias III. (Lecture topic of the 9th week).

*

Cardiovascular system II.: Pathophysiology and ECG of acute Seminar: Cardiovascular coronary syndromes: angina pectoris, myocardial infarction, sudden system I. (Lecture topic of the ischemic death. 10th week).

*

Cardiovascular system III.: Hypertension (essential & Seminar: Cardiovascular secondary) development, risk factors and consequences. Congenital system II. ECG: Myocardial heart diseases I. ischemia, injury and infarction (Lecture topic of the 11th week).

*

Cardiovascular system IV.: Congenital heart diseases II. Adaptation of the heart, hypertrophy. Mitral, aortic stenosis and regurgitation. Compensated and decompensated heart function, left, right and combined heart failure.

Seminar: Cardiovascular system III. (Lecture topic of the 12th week). ECG: Hypertrophy and repetition of ECG

*

Peripheral circulatory diseases: Volume depletion. Syncope. Circulatory shock (development, stages). Multiple organ dysfunctions in shock. Hypotension.

Seminar: Cardiovascular system IV. (Lecture topic of the 13th week).

6th semester LECTURE (3 hrs/week)

PRACTICE/SEMINAR (2 hrs/week)

*

Pathophysiology of kidney diseases I.: Kidney stones. Polyuria, Safety regulations. oliguria and anuria. Acute renal failure and tubulointerstitial Seminar: Thermoregulation. nephropathies. (Please download and study the material from our website or coospace, before class).

*

Pathophysiology of kidney diseases II.: Major glomerular diseases: nephrotic and nephritic syndrome, RPGN, asymptomatic and chronic GN. Chronic renal failure. Tubular transport diseases. Pathophysiology of salt-water balance I. hyper- and hyponatremia

Seminar: Kidney diseases I., Pathophysiology of salt-water balance I. (Lecture topic of the 1st week) In the practice room: Investigation of urine and renal function: proteinuria, hematuria, pyuria, hemoglobinuria, ketone bodies, urobilinogen, urine sediment

108 and casts.

*

Pathophysiology of salt-water balance II. Volume excess, development of edemas. Changes of potassium, calcium, magnesium, phosphate, chloride and trace elements under pathological conditions; ECG signs of electrolyte disturbances.

Seminar: Pathophysiology of salt-water balance I (Lecture topic of the 2nd week) In the practice room: Investigation of urine and renal function: proteinuria, hematuria, pyuria, hemoglobinuria, ketone bodies, urobilinogen, urine sediment and casts.

*

Pulmonary diseases I: Abnormal breathing patterns, dyspneas. Obstructive pulmonary diseases: CODP, asthma bronchiale, cystic fibrosis, bronchiectasis, bronchiolitis acuta.

Seminar: Pathophysiology of salt-water balance II (Lecture topic of the 3rd week)

*

Pulmonary diseases II: Restrictive pulmonary diseases, Seminar: Pathophysiology of hypoxias, disorders of pleura, pulmonary edema, hypertension, pulmonary diseases I. (Lecture embolisation, hypoxic conditions, respiratory failure. Cor pulmonale. topic of the 4th week).

*

Disturbances of acid-base metabolism: Laboratory changes in acid-base diseases. Respiratory acidosis and alkalosis. Normo- and hyperchloremic metabolic acidosis. Chloride responsive and nonresponsive metabolic alkalosis.

Seminar: Pathophysiology of pulmonary diseases II. (Lecture topic of the 5th week).

*

Gastrointestinal diseases I.: Nausea, vomiting, dysphagia. Abnormalities of gastric juice secretion, peptic ulcer.

Seminar: Disturbances of acidbase metabolism (Lecture topic of the 6th week).

*

Gastrointestinal diseases II.: Diseases of absorption, diarrhea, Seminar: Gastroenterology I. constipation: Irritable bowel syndrome. Intestinal obstruction. Acute (Lecture topic of the 7th week). and chronic pancreatitis.

*

Diseases of liver and biliary tract: Abnormal liver function. Diseases of bilirubin metabolism: hemolytic, hepatocellular and obstructive jaundice. Cirrhosis hepatic. Liver failure. Alcoholic, immune and genetic liver diseases. Cholelithiasis.

*

Seminar: Pathophysiology of Pathophysiology of leukocytes II.: Leucopenia. Proliferative diseases: reactive and malignant diseases (leukemias, lymphomas). liver diseases (Lecture topic of the 10th week).

*

Red blood cell diseases I.: Anemias - ineffective erythropoesis, blood loss, hemolysis.

Seminar: Pathophysiology of leucocytes II. (Lecture topic of the 11th week)

*

Hemostasis: Bleeding disorders (platelet, vascular, clotting factor disturbances), thrombosis and embolism.

Seminar: Anemias (Lecture topic of the 12th week). In the practice room: Determination of WBC, RBC, platelet, eosinophyl and reticulocyte count. Staining and analysis of blood smear.

*

Pathophysiology of the CNS I.: Multiple sclerosis, neurodegenerative diseases: Alzheimer’s, Parkinson’s and Huntington’s disease. Circulatory diseases of the CNS.

Seminar: Hemostasis (Lecture topic of the 13th week). In the practice room: Determination of WBC, RBC, platelet, eosinophyl and reticulocyte count. Staining and

Seminar: : Gastroenterology II. (Lecture topic of the 8th week).


109 analysis of blood smear.

*

Pathophysiology of the CNS II.: Cerebral edema. Pain, headaches, seizures and epilepsy.

Seminar: Pathophysiology of the CNS. (Lecture topic of the 14th week).

HUNGARIAN LANGUAGE 5th semester

* *

* *

* * * * * * *

* * *

PRACTICE (2 hrs/week) Introduction to the course. The name of various clinical departments, the medical and nursing staff working there. Revision of the Present Tense. Introduction to history taking. The parts of the case history. Asking and answering questions concerning present condition and pain: location, type, and duration, aggravating and relieving factors. Yes/No questions. Asking the patients about previous hospitalisation and operations, major health problems, childhood diseases and vaccination. Revision of the Past Tense. Wh-questions. Taking family and social history. Revising family relations, marital status, harmful habits (e.g. smoking, uncontrolled alcohol consumption, illegal drugs, excessive caffeine intake). Revising numbers and measurements. Practising basic doctor-patient situations: role-play, history taking. Asking about presenting symptoms/ present complaints, past history, family and social history. Asking the patient about dizziness, sweating, nausea or vomiting. Revision of Adjectives and Adverbs. Practising the Comparative and the Superlative. Interviewing the patient about dyspnoea, cough and sputum. Revision of the Future Tense. Mid-term test. Questions and answers concerning heart complaints and oedema of the legs. Revision of the Definite and Indefinite Articles. Practising doctor-patient situations: role-play, history taking. Briefing simple English case histories in Hungarian. Asking the patient about appetite, stools and urine. Revision of Modifiers and Quantifiers, and the vocabulary concerning food and drinks. Questioning the patient about changes in his/her temperature. Questions about having fever, measuring fever and decreasing high temperature. Revising the vocabulary concerning the main parts of the body. General instructions to patients during physical examination. The polite way of giving instructions. Revision of the Imperative Voice. The most common conditions and diseases in Internal Medicine in Hungary: diseases of the digestive, cardiovascular and respiratory systems. Practising doctor-patient situations: role-play, history taking. Briefing English case histories taken from the field of Internal Medicine in Hungarian. Final tests (written and oral).

6th semester

* * *

* *

PRACTICE (2 hrs/week) The type of drugs/medicines. Internally and externally administered drugs. Vocabulary expansion concerning forms of medicines and their containers. The effect of drugs. Most common adverse effects. Explaining to patients how to take the prescribed medicines. General instructions. Practising doctor-patient communication: role-play, history taking and giving advice to patients concerning medication. Reading simple Hungarian case histories taken from the field of Internal Medicine. Surgery. Interviewing the patient at the Surgery Department. General and more specific questions. Parts of the digestive tract. The most common problems of the digestive tract. Role-play, history taking of patients with

110 * *

*

* *

* * *

*

oesophageal problems. Interviewing a patient with gallbladder complaints. Interviewing patients with abdominal complaints. Discussing case histories involving acute intestinal problems: appendicitis and ileus. Physical examination of the patient with acute abdominal complaints. Interviewing patients with complaints referring to herniation. Chronic conditions in the colon: tumours of the large intestine and rectum. Sending patients for further investigations. Vocabulary concerning basic imaging techniques. Mid-term test. Practising doctor-patient communication at the Surgery department: role-play, history taking and discussing possible surgical intervention with the patient. Revising the Conditional Mood. Briefing simple English case histories taken from the field of Surgery in Hungarian. Interviewing patients who suffer from problems of the thyroid gland. Interviewing patients with breast cancer. Giving advice concerning life style. Revising Auxiliary Verbs. Discussing the most common vascular problems. Interviewing patients with hypertension, vasoconstriction and varicose veins. Giving instructions concerning life style and medication. Discussing and arguing with patients. Acute cases of the vascular system: embolism and thrombosis. Interviewing patients presenting with symptoms of embolism and thrombosis. Management of acute cases. Patients at the Traumatology department. Home, road and sports accidents. Asking patients about conditions caused by accidents. Explaining medical procedures and giving advice to patients. Practising doctor-patient communication: role-play, history taking and giving advice to patients concerning treatment and medication. Reading simple Hungarian case histories taken from the field of Surgery and Traumatology. Revision. Practising doctor-patient situations that can emerge in the Internal Medicine, Surgery and Traumatology department. Interviewing and examining patients, sending them for further investigations, giving advice on diet, life style and medication. Final tests (written and oral).

ADVANCED SURGICAL SKILLS 5th, 6th, 7th, 8th, 9th or 10th semester

*

*

*

*

LECTURE (2 hrs/week) Laparotomy I. Abdominal pain. History of abdominal surgery. Technical background and basic principles of abdominal incisions. Anatomy, vessels and nerves of the abdominal wall. Factors affecting wound healing. Prevention of wound complications. Surgical intervention: anesthesia, positioning, skin preparation, draping, incisions, supplies Laparotomy II. Abdominal incisions. Major types, characteristics, advantages, disadvantages. Extraperitoneal incisions for staging. Wound closure. Drainage. Laparatomy in obese patients. Wound dehiscence (characteristics, types, repair). Irrigation. Basic gastrointestinal operations. Surgical disease conditions. Appendectomy (history, anatomy). Open appendectomy Abdominal drainage. Invasive diagnostic techniques. Acute (diagnostic) peritoneal lavage. Chronic (therapeutic) peritoneal lavage (peritoneal dialysis). Postoperative abdominal lavage/drainage (indications, main types, problems). Anastomoses (types, factors influencing healing). Anastomosis techniques. Intestinal anastomoses. Indications, principles and steps of bowel resection and anastomosis. Postoperative care Basic thoracic techniques. Thoracic trauma (localization, types, general considerations). Pleural effusion. Hemothorax. Pleural injury. Pneumothorax. Open and closed (tension) pneumothorax. Thoracocentesis, chest tubing, chest drainage systems. Flail chest. Cardiac tamponade. Pericardiocentesis. Etiology, clinical manifestations and treatment of the diseases

PRACTICE (4 hrs/gr./every 2nd week) Scrubbing. Basic knotting and suturing techniques.

Advanced suturing techniques. Would closure techniques with multiple layers. Enterotomy. Intestinal anastomosis

The Minor Skin Procedures computer program. Local anesthesia. Ellipse excision of skin. Removal of encapsulated structures (cysts, tunors). Incision of abscesses. Minimally invasive surgery.

Advanced forms of surgical hemostasis and suturing techniques on a large animal model. Tracheostomy. Laparotomy


Minimally invasive surgery I. Technical background. Equipments and instruments. Robotic and fetoscopic surgery

*

Minimally invasive surgery II. Pneumoperitoneum (pathophysiology, complications, diagnosis, treatment). Gastro-enteroanastomoses. Laparoscopic surgery. Laparoscopic cholecystectomy Written test exam

*

111

BASICS OF EMERGENCY MEDICINE 6th semester

*

*

*

*

LECTURE (2 hrs/week) Bioinstrumentation. Bioengineering. Medical devices (risk classes, therapeutic and monitoring devices). Basic metrology. Types, categories and definitions of measurements. Monitoring (guidelines, monitor categories). Non-invasive cardiovascular monitoring. Clinical observations. Pulse examination, indirect blood pressure measurement, pulse pressure, electrocardiography, pulse-oximetry. The Dopplertechnique: flowmetry, echocardiography Invasive cardiovascular monitoring. Direct (invasive) blood pressure measurements: arterial pressure, central venous pressure, pulmonary artery pressure (sites for cannulation, Seldinger technique, SwanGanz catheter, methods, equipment, indications, complications). Blood flow, cardiac output measurements. Oxygen delivery, saturation and consumption measurement (central and mixed venous O2). Heart contractility Monitoring of respiration and gas exchange. Clinical respiratory patterns. Spirometry. Airway gas (CO2) monitoring (capnography, capnometry). Air embolism, pulmonary embolism (diagnosis, prevention, treatment)

PRACTICE (4 hrs/gr./every 2nd week) Injections. Puncture and cannulation of veins (braunule). Taking blood samples. Venous cut-down ex vivo. The Seldinger technique. Practising on phantoms and a Virtual Reality simulator (Cathsim). Fluid therapy in practice. Infusions, infusion pumps

Injections. Puncture and cannulation of veins (braunule). Taking blood samples. Venous cut-down ex vivo. The Seldinger technique. Practising on phantoms and a Virtual Reality simulator (Cathsim). Fluid therapy in practice. Infusions, infusion pumps

Invasive cardiovascular monitoring. Securing of central vein (dissection of veins, introduction of central venous catheter using the Seldinger technique). Measurement of central venous pressure. Dissection of arteries, direct measurement of arterial pressure. Determination of cardiac output using the transpulmonary thermodilution method. Arterial blood flow measurements. Monitoring of pulmonary circulation. Introduction of Swan-Ganz catheter into the pulmonary artery, pressure measurements. Thermodilution cardiac output measurement with the aid of Swan-Ganz catheter Monitoring of oxygenation and hypoxia. Inadequate Invasive cardiovascular monitoring. Securing of external respiration, O2 transport, internal central vein (dissection of veins, introduction of respiration. Hypoxemia, tissue hypoxia, subcellular central venous catheter using the Seldinger hypoxia (etiology, pathophysiology, clinical signs and technique). Measurement of central venous pressure. symptoms). Tissue oxygenation and wound healing. Dissection of arteries, direct measurement of arterial Clinical assessment of tissue hypoxia. Diagnostic pressure. Determination of cardiac output using the assessment of oxygen delivery, extraction, transpulmonary thermodilution method. Arterial requirement and consumption. Monitors of blood flow measurements. Monitoring of pulmonary hypoperfusion-associated hypoxia and tissue circulation. Introduction of Swan-Ganz catheter into oxygenation (tissue oxymeter, Clark electrode, near the pulmonary artery, pressure measurements.

112

*

*

*

infrared spectroscopy); organ perfusion (macrocirculation: angiography and flowmetry; microcirculation: intravital microscopy, orthogonal polarization spectral imaging) and mucosal pCO2 (clinical tonometry). Blood acid-base status, blood gas analysis. Extracorporal membrane oxygenation Monitoring of urinary system. Catheters. Analysis of urine. Blood laboratory parameters indicating renal function. Imaging techniques. Urinary bladder pressure. Monitoring of central nervous system. Measurement of intracranial pressure (ICP), cerebral blood flow and cerebral perfusion pressure. Increased ICP (etiology, pathology, diagnosis, treatment). Monitoring of temperature (sites, methods). Hyperthermia, hypothermia (pathophysiology, clinical signs, treatment) Monitoring of gastrointestinal tract. Measurement of intrabdominal pressure (direct, indirect methods; intravesical pressure), abdominal compartment syndrome (etiology, pathopysiology). Monitoring of nutrition (anamnesis, clinical assessment, anthropometry, laboratory analysis, calorimetry). Feeding (indications, nutrients). Enteral feeding. Gastric intubation, nasogastric and orogastric tubes (types, indications, contraindications, tube insertion). Gastrostomy, jejunostomy. Feeding formulas, methods, complications. Parenteral feeding. Indications, nutrient solutions, complications (postagression syndromes). Enemas, laxation Written test exam

MICROSURGERY 5th, 6th, 7th, 8th, 9th or 10th semester LECTURE (TOTAL: 8 hrs) * General information. introduction to microsurgery (1 hrs) * Indications of microsurgery. Personal and technical conditions of microsurgery. Asepsis in microsurgery (2 hrs) * Clinical applications of microsurgery (2 hrs) * The operating microscope (1 hr)

* *

Thermodilution cardiac output measurement with the aid of Swan-Ganz catheter

Complex monitoring. Monitoring of respiratory system. Endotracheal intubation; monitoring of respiratory rate, rhythm and airway gases (capnography, capnometry). Pulse oxymetry. Blood gas analysis. Mechanical ventilation. Monitoring of gastrointestinal tract. Indirect (gastric, intestinal and sublingual) tonometry. Monitoring of microcirculation (intravital videomicroscopy, orthogonal polarization spectral imaging). Monitoring of urinary system. Catheterization of the urinary bladder (male, female) Complex monitoring. Monitoring of respiratory system. Endotracheal intubation; monitoring of respiratory rate, rhythm and airway gases (capnography, capnometry). Pulse oxymetry. Blood gas analysis. Mechanical ventilation. Monitoring of gastrointestinal tract. Indirect (gastric, intestinal and sublingual) tonometry. Monitoring of microcirculation (intravital videomicroscopy, orthogonal polarization spectral imaging). Monitoring of urinary system. Catheterization of the urinary bladder (male, female)

Practical exam

PRACTICE (TOTAL: 20 hrs)

Appropriate posture at the operating microscope and the adjustment of the microscope. Movement coordination of the hands: interlacing threads under microscope (1 hr) Tying basic microsurgical knots under macroscopic and microscopic conditions (2 hrs)

Basic suturing techniques, sutures of vessels and nerves (2 hrs)

* * * * * *

MOLECULAR MEDICINE

Stitching and tying knots with microsurgical instruments on rubber gloves (3 hrs) Stitching and tying knots with microsurgical instruments on rubber gloves (2hrs) Suture of tubes (3 hrs) Suture of tubes (3 hrs) End-to-end anastomosis of rat carotid artery ex vivo (3 hrs) End-to-end anastomosis of rat carotid artery ex vivo (3 hrs)

Curriculum 2014/2015 5th semester

* * * * * * * * * * * * * * * *

LECTURE (2 hrs/week) Molecular genetic and cell biology methods in diagnosis and therapy. Diagnostic methods based on immunologic techniques (RIA, ELISA, Western blot analysis, immunocytology, citotoxicity tests, etc.). Diagnostic methods beased on nucleic acid hybridization (Northern and Southern analysis, in situ hybidization, DNA chip technology, etc.). Diagnostic methods based on specific endonuclease activity (fragment length polymorphism, pedigree analysis, etc.). Gene sequencing and analysis, genomic and proteomic techniques, cell and tissue culture methods. Antisense pharmacology. Small interfering RNA. Molecular chaperons. Gene therapy, viral vectors, DNA-liposome complexes. Molecular markers in human disorders. Biomarkers for neurologic and psychiatric disorders. Molecular interactions between pathogens and host. Stem cell therapy. Embryonal and adult stem cells. In vitro differentiation of stem cells to the desired phenotype. Transfection of stem cells. Regulation of cell cycle and cell differentiation. Regulation of transcriptional and translational control of gene expression. Telomerase-directed molecular therapy. Immunotherapy. Antitumour immune responses. Bioinformatic and computer-assisted methods in diagnosis and therapy: functional genomics and proteomics.

PATHOPHYSIOLOGICAL ASPECTS OF LABORATORY MEDICINE 6th semester

*

* * *

*

* * *

* *

* *

LECTURE (2 hrs/week) Introduction to laboratory medicine Preanalytical processes, test requesting, sampling, common preanalytical errors Analytical processes: quality control, traceability of measurements, precision, biological variation, reference range, point of care testing. Postanalytical processes: interpretation of results, sensitivity, specificity, predictive values, pre- and post-test probability, clinically significant change values, alarming or critical values, evidence based laboratory medicine Visit at the Department of Laboratory Medicine Acid-base balance disorders Laboratory diagnosis of coagulation disorders Basic coagulation tests, monitoring of anticoagulant therapy, testing for congenital and acquired thrombophilias Laboratory diagnosis of sodium and water metabolism Hypo- and hypernatremia: causes and differential diagnosis, SIADH, diabetes insipidus, laboratory diagnosis of oedema. Effect of diuretics on sodium and water balance, disorders of osmolar regulation Disorders of potassium metabolism Hypo-, and hyperkalemia: causes and differential diagnosis, diagnostic algorithms and treatment Laboratory diagnosis of liver diseases Endocrinology I. Laboratory diagnosis of disorders of endocrine regulation. Diseases of hypothalamus, hypophysis, thyroid and parathyroid glands. Endocrinology II. Laboratory diagnosis of disorders of the adrenal gland and the reproductive system Laboratory diagnosis of disorders of lipid metabolism Primary, and secondary hyperlipidemia, clinical significance of cholesterol, TG, HDL-C, LDL-C, classification of hyperlipidemias. Risks of atherosclerosis: clinical significance of ApoA, ApoB, Lp(a), homocystein, fibrinogen. Laboratory diagnosis and monitoring of diabetes mellitus Laboratory diagnosis of renal diseases

113

114

*

Laboratory tests of glomerular and tubular functions, laboratory diagnosis of proteinuria, acute and chronic renal failure, nephrosis syndrome, differentiation of distal and proximal renal tubular acidosis Laboratory diagnosis of myocardial infarction and acut coronary syndrome Classical markers: CK, LDH isoenzymes, myoglobin. New markers: Troponin I, Troponin T, significance of point of care testing, diagnostic algorithms.

BASIC SURGICAL SKILLS 5th semester

*

LECTURE PRACTICE (2 hrs/every 2nd week) (2 hrs/gr./every 2nd week) Asepsis and antisepsis. Historical background. Surgical infections, sources of infections. Types, classification, risks and prevention of wound contaminations. Sterilization, disinfection. Preparation of the patient before operation: scrub preparation and isolation of the surgical site. Scrubbing, disinfection, gowning and gloving of the operating team. Personnel attire and movement. Basic rules of asepsis in the operating room. Postoperative wound management. Surgical antisepsis. Design and equipments of the operating room, basic technical background. Operating room personnel and their duties. Positioning of the patient on the operating table

*

General information. Scrubbing, gowning and gloving. Practical rules of asepsis in the operating room. Behavior and movement in the operating room

*

Surgical instruments. Basic surgical instruments, special surgical tools and technologies, suture materials. Wound closure (sutures, clips, adhesive strips). Imperfections of suturing techniques. Removal of sutures. Drainage. Basics of minimally invasive surgical interventions. Historical background. Components of the laparoscopic tower, laparoscopic instruments

*

Basic surgical instruments, suture materials, textiles. Scrubbing, gowning and gloving. Scrub preparation and draping of the surgical site. Tying surgical knots (hand and instrument knots) The operation. Basic surgical interventions. Basic surgical instruments, suture materials, textiles. Indications for an operation, informed consent, Scrubbing, gowning and gloving. Scrub preparation operative risk, the surgeon’s responsibility. and draping of the surgical site. Tying surgical knots Preoperative investigations. Complications of (hand and instrument knots) surgery. Preoperative preparation of the patient. Local anesthesia (drugs, types of local anesthesia, complications). Perioperative fluid balance, fluid requirements and fluid therapy Tying surgical knots. Knotting under tension and in cavities

*

* *

*

Wounds. Types and classification of accidental wounds. Wound healing, scar formation. Surgical wounds. Wound closure and its complications. Management of accidental wounds. Dressings, types of bandages. Innovations in wound treatment

General information. Scrubbing, gowning and gloving. Practical rules of asepsis in the operating room. Behavior and movement in the operating room

Tying surgical knots. Knotting under tension and in cavities

Skin incision, handling bleeding, closing wounds in


*

*

*

*

*

115

separate layers with sutures or with wound clips. Draining of wounds. Knotting with an instruments using the Suture Tutor program Bleeding. Types and classification of Skin incision, handling bleeding, closing wounds in hemorrhage. Signs and consequences of blood separate layers with sutures or with wound clips. loss. Bleeding in surgery (pre-, intra- and Draining of wounds. Knotting with an instruments postoperative bleeding). Factors influencing using the Suture Tutor program operative blood loss. Surgical hemostasis (mechanical, thermal, chemical-biological methods). Blood replacement in surgery, autotransfusion Management of accidental wounds. Dressing, types of dressing. Changing dressing under aseptic conditions. Removal of sutures Complications. Definition and classification of Management of accidental wounds. Dressing, types complications. Complications of wound of dressing. Changing dressing under aseptic healing. Complications related to surgery. conditions. Removal of sutures Haemorrhagic complications. Pathophysiology, signs and treatment of hemorrhagic shock

Written test exam

Basics of minimally invasive surgery. Components of the laparoscopic tower, laparoscopic instruments. Eupractic movements, handling of laparoscopic instruments, knotting Basics of minimally invasive surgery. Components of the laparoscopic tower, laparoscopic instruments. Eupractic movements, handling of laparoscopic instruments, knotting Practical Exam

BASIC IMMUNOPATHOLOGY 6th semester

* * * * * * * * *

LECTURE (2 hrs/every 2nd week) General informations. Introduction to immunopathology. Transplantation immunology: transplantation antigens, allogeneic recognition, effector mechanisms of graft rejection Histocompatibility testing. Immunological investigations before and after transplantation. Immunosuppressive therapy Immunology of organ transplantation. Immunology of bone marrow transplantation: graft-versus-host disease. Xenogeneic transplantation Reproductive immunology Tumor immunology: tumor antigens, antitumor immune responses. Evasion of immune responses by tumors. Immunotherapy for tumors Immunological tolerance. Self tolerance: central and peripheral tolerance. Mehanisms of T and B cell tolerance Pathomechanisms of autoimmunity: failure of self tolerance, genetic factors, role of infections and other factors; effector mechanisms. Systemic and organ specific autoimmune diseases Written test exam

CEREBRAL BLOOD FLOW AND METABOLISM 5th semester

* * * * * *

LECTURE (2 hrs/week) Introduction – requirements-general view Methods for investigation of cerebral blood flow and metabolism The physiology of the cerebrovascular smooth muscle Regulation of the cerebrovascular tone * the role of the endothelium Regulation of the cerebrovascular tone * the neural components Regulation of the cerebrovascular tone * the metabolic components

116 * * * * * * * *

Blood supply and basal metabolic processes in the brain The neurovascular coupling The transport to the brain-the blood brain barrier The blood supply of the dura mater cerebri The regulation of the cerebral blood flow in the neonate Ageing and cerebral blood flow Basic pathomechanism of the stroke Exam

GERONTOLOGY 6th semester

*

LECTURE/PRACTICE (1 hr/week, 1 hr/week) General principles of geriatric medicine

*

History taking with elderly patients

*

Physicial examination

*

Mental status examination

*

Evaluation of functional capacity in him elderly

*

Laboratory examination

*

Progressive constriction of each organ systems

*

Intellectual impairment

*

Immobility

*

Iatrogenic drug reactions

*

Community of care

*

Quality of life and therapeutic objectives

*

Legal and ethical issues

*

Care of the dying patient


117 SYLLABUSES CLINICAL MODULE - MEDICINE

ANAESTHESIOLOGY AND OXYOLOGY 9th semester (Basics, anaesthesiology)

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13.

LECTURE/PRACTICE (2 hrs/week, 1 hr/week) Introducing anaesthesiology and intensive therapy Applied physiology – I. Breathing, oxygen therapy Applied physiology – II. Circulation, circulation management Applied physiology – III. Acid-base balance, blood-gas analysis Monitoring airway, circulation, sleep in the operating room Methods of air flow management Fluid therapy – fluid resuscitation Assessment of operation hazards, preoperative preparation Respirator, respiratory system General anaesthesia, anaesthetics Regional anaesthesia, local anesthetics Postoperative patient care, postoperative complications, significance of PACU Postoperative and acute analgesia

10th semester (acute care, intensive therapy)

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 11. 12. 13.

LECTURE/PRACTICE (2 hrs/week, 1 hr/week) Theory of sudden death and resuscitation (BLS, ALS) Methods of invasive hemodynamic measurement The respirator Infection, infection control Severe sepsis, septic shock Acute respiratory dysfunction and ARDS Acute metabolic dysfunction and their treatment Recognition and treatment of acute cardiovascular diseases Low GCS, coma, brain death Basics of clinical nutrition Main aspects in the acute treatment of polytraumatized patient Acute treatment of intoxicated patient Chronic pain, pain clinic Recognition and acute treatment of multi-organ dysfunction

118

CLINICAL ONCOLOGY 7th semester LECTURE (2 hrs/week) 6-Sep Cancer etiology, epidemiology. Tumor prevention

Prof. Dr. Zsuzsanna Kahán

13-Sep

The basics of Radiotherapy

Dr. Elemér Szil

20-Sep

The importance of pathology and diagnostic imaging in oncology; AJC/UICC TNM system


27-Sep

Practical aspects of Radiotherapy

Dr. Elemér Szil Dr. Katalin Hideghéty Dr. Zoltán Varga

4-Oct 11-Oct 18-Oct 25-Oct 8-Nov 15-Nov 22-Nov 23-Nov 29-Nov

Medical therapies: chemotherapy, endocrine therapy, biological therapies Supportive, palliative therapy and the holistic approach; psychooncology


Breast cancer and gynecological malignancies The complex therapy of head and neck, oesophagus and gastric cancers The complex therapy of liver, pancreas and colorectal tumors Genitourinary malignancies


Lung cancer and mesenchymal tumors

Dr. Anikó Maráz


Dr. Katalin Hideghéty Prof. Dr. Zsuzsanna Kahán Dr. Anikó Maráz

Dr. Katalin Hideghéty Central nervous system, childhood and skin malignancies

Dr. Katalin Hideghéty

6-Dec

Multidisciplinary team-work


13-Dec

EXAM

DERMATOLOGY 9th semester

*

LECTURE (3 hrs/week) Introduction. The anatomy and physiology of the skin. Types of skin lesions.

*

Basic immunpathologic reactions. Urticaria. Drug allergy.

*

Atopic dermatitis. Contact der-matitis and other eczematous reactions. Viral diseases.

*

Bacterial diseases with cutan involvement. Fungal diseases with cutaneous involvement.

*

Tuberculosis of the skin. Sexually transmitted diseases. Syphilis. Gonorrhoea.

*

AIDS. Scabies, pediculosis. Tropical skin diseases.

*

Psoriasis. Papulosquamosus diseases. Thermally injured skin.

PRACTICE (2 hrs/week) Examination of patients with dermatological diseases. Case presentations. Primary and secondary lesions. Case presentations. Special tools and techniques in Dermatology (Wood-lights, diascopy, dermatoscopy) Case presentations. Special tests in Dermatology I.In vitro and in vivo (skin) tests in allergic disorders. Case presentations. Special tests in Dermatology II. Diagnosis of infectious diseases. Case presentations. Special tests in Dermatology. Diagnosis and treatment of STD. Case presentations. Special tests in Dermatology III. Diagnosis of autoimmune diseases. Case presentations.


* *

*

*

*

*

119

Vesiculobullosus diseases. Acne, rosacea, perioral dermatitis.

Skin biopsy, histological examinations in Dermatology. Case presentations. Disorders of collagen and tissue. Vasculitis, purpuric conditions. Topical therapy in Dermatology. Case presentations. Cutaneous manifestations in metabolic disorders. Benign malign Physical therapies in tumours of the skin. Dermatology I. Surgical excision, currettage, electrodessication, cryotherapy, radiotherapy. Case presentations. Tumours of mesodermal origin. Melanoma malignum. Differential Physical therapies in diagnosis of pigmented lesions. Dermatology II. Phototherapy, lasertherapy. Case presentations. Disorders of the vasculature. Granulomas. Disorders with abnormal Physical therapies of venous and keratinization. The skin in systemic disease. lymphatic insufficienties. Case presentations. Disorders of the hair and nails. UV-induced dermatoses. Laser Systemic therapy in therapy in dermatology. Dermatology. Case presentations. Local therapy in dermatology. Systemic therapy in dermatology. Case presentations and Dermatosurgery. discussions.

FORENSIC MEDICINE 9th semester

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15.

LECTURE (1 hr/week) Introduction. Essential law What to do with a dead body? Recommendation on autopsy rules Types of injuries I. (blunt force, sharp object injuries) Types of injuries II. (heat, cold, shot wounds) Fall break Midterm demonstration (written) Scientific session Forensic psychiatry Forensic aspects of alcohol consumption Asphyxia, drowning

PRACTICE (2 hrs/week) Time of death Changes after death How to fill out a death certificate? Autopsy Hystology (vitality signs) Classification of wounds Autopsy Scene investigation, sample collection Toxicology Autopsy Poisoning Suicide Autopsy Consultation Supplementary practice

FORENSIC MEDICINE 10th semester

1. 2. 3. 4. 5.

LECTURE (2 hrs/every second week) Traffic accidents I. Traffic accidents II. Forensic aspects of drug abuse

PRACTICE (2 hrs/week) Hystology (sudden death in adults) Toxicology Autopsy Malpractice Reconstruction of accidents and criminal cases

120 6. 7. 8. 9. 10. 11. 12. 13.

Medical duties in relation to custody Social insurance systems Spring break Identification of the living and of the dead Sexual offences. Battered child, infanticide

14. 15.

Consultation

Autopsy Midterm demonstration Visit in the county jail Use of DNA in forensic medicine Autopsy Identification Assessment of working ability and disability Autopsy Autopsy

INTERNAL MEDICINE 7th semester

* *

LECTURE (5 hrs/week) Echocardiography Infective endocarditis. Tumors of the heart Hypertension in cardiologic aspect. Aortic dissection Aortic stenosis +Aortic incompetence. Mitral stenosis + Mitral incompetence Tricuspid stenosis and incompetence. Combined valvular heart disease. Prosthetic valve. Rheumatic fever. Myocardtitis and pericarditis Adult congenital heart diseases Hypertrophic and dilatative cardiomyopathy: diagnosis and treatment Electrocardiography Cardiac arrhythmias

*

Ischemic heart diseases

*

Invasive diagnostic and theraputic methods in cardiology Restrictive and obliterative cardiomyopathy. Chronic heart failure Pulmonary embolism. Pulmonary hypertension. Cardiac rehabilitation Special cardiac conditions: women, athletics, elders. Cardiac risk stratification in non cardiac surgery Acute heart failure. Failure of periferial circulation Revascularization in cardiac surgery Basic hematology Anemias

* * * * * *

* * *

*

* * *

* * * *

PRACTICE (2 hrs/week) Methods in echocardiography, reading an echocardiographic record. Taking the case history the physical examination. Performing percussion, auscultation. Performing percussion, auscultation. Performing percussion, auscultation. Performing percussion, auscultation.

The physical findings of rheumatic fever and inflammatory diseases. Performing percussion, auscultation. Performing percussion, auscultation. The physical findings of cardiomyopathies. Reading ECG records. Reading ECG records learning modern antiarrhythmic treatment and procedures. Non invasive and invasive technics in the diagnosis of ischemic heart disease. Non invasive and invasive technics in the diagnosis of ischemic heart disease. Performing percussion, auscultation. The physical findings of cardiomyopathies and chronic heart failure. Physical findings of pulmonary embolism and hypertension. Possibilities in rehabilitation program. Non invasive and invasive technics in cardiology.

The signs and treatment of heart failure and periferial circulation disturbances. Visiting at operation theatre. Evaluation of laboratory data Inspection of patients with anaemia

Curriculum 2014/2015 * * * * * * * * * * * *

Anemias. Hemolytic anemia Pancytopenias (Myelodysplastic syndromes. Aplastic anemia) Acut leukemia Stem cell transplantation Myeloproliferative diseases Malignant lymphomas. (Classification, Hodgkin disease) Aggressive lymphomas

121 Microscopic evaluation of red cells morphology Bone marrow smears examination, physical signs of pancytopenic patients Examination of blood and bone marrow smears with acute leukemias Discussion of indications for stem cell transplantation Palpation of spleens and enlarged livers Lymp nodes palpation

Examination of blood and bone marrow smears with lymphomatic infiltration X ray consultation, physical examinations

Malignant lymphomas. (Indolent lymphomas, multiple myeloma) Coagulation abnormalities. Bleeding manifestations (Thrombophilias)

8th semester

*

LECTURE (5 hrs/week) Esohpageal disorders

*

Peptic ulcer disease

* *

*

*

*

*

* *

*

*

PRACTICE (2 hrs/week) Problem oriented evaluation of the symptoms of patients with esophageal disorders Practical aspects of the functional evaluation of patients with esophageal disorders (esophageal manometry, 24 h pH-metry, evaluation of the biliary reflux)

Functional dyspepsia Gastrointestinal hormones Upper gastrointestinal endoscopy Gastric Cancer Chronic hepatitis Symptomatic evaluation of the liver patient. Cirrhosis of the liver I. Problem oriented laboratory investigation of the liver patient. (etiology, symptoms) Cirrhosis of the liver II Symptoms of biliary obstruction, investigative methods for patients (complications, therapeutical with biliary obstruction (symptoms, biochemistry, ultrasonography, options) ERCP) Diseases of the biliary system I Diseases of the biliary system Symptoms of patients with acute pancreatitis II Acute pancreatitis Diagnostic work up of patients with acute pancreatitis Chronic pancreatitis Diagnostic work up of patients with chronic pancreatitis and pancreatic cancer Pancreatic cancer Pathomechanisms of Diagnostic work up of patients with CU and Crohn’s disease. Inflammatory Bowel Disease Crohn’s disease and Ulcerative Colitis Tumors of the large intestine Early identification of patients with colorectal cancer. Diagnostic methods. Malabsorption syndrome Irritable Bowel Syndrome Symptoms of malabsorption, maldigestion, Diagnostic workup: Hydrogen, c13 urea and starch breath tests Diabetes mellitus (etiology, classification) Complications of diabetes Practical aspects of the diagnosis and therapy of patients with mellitus diabetes mellitus; the patient education. Therapy of diabetes mellitus Dyslipoproteinemias Practical aspects of insulin therapy. Treatment of dyslipoproteinemias Hyperuricemia, gout

122 *

*

Introduction to clinical immunology Rheumatoid arthritis SLE, Dermatomyosistis, Sjögren’s disease, MCTD Consultation

Physical examination of patients with rheumatoid diseases

Consultation

9th semester

*

* * * * * * * * * * * * *

LECTURE (2 hrs/week) History, principles, distribution of infectious diseases. Epidemiological problems. Pathogenetic agents. Pathophysiology and diagnosis of infectious diseases. Infections of the respiratory organs. Infections of the gastrointestinal tract Neuroinfections Hepatitis AIDS Sepsis Prevention of infectious diseases Exanthematous infectious diseases Antropozoonoses (Lyssa, Brucellosis, Tularemia etc.) Antimicrobal therapy Nosocomial infections Tropical diseases

PRACTICE (2 hrs/week) History, principles, distribution of infectious diseases. Epidemiological problems. Pathogenetic agents.

Pathophysiology and diagnosis of infectious diseases. Infections of the respiratory organs. Infections of the gastrointestinal tract Neuroinfections Hepatitis AIDS Sepsis Prevention of infectious diseases Exanthematous infectious diseases Antropozoonoses (Lyssa, Brucellosis, Tularemia etc.) Antimicrobal therapy Nosocomial infections Tropical diseases

10th semester

* * * * * * * * * * *

* * *

LECTURE (2 hrs/week) Diarrhea, constipation Abdominal pain Ascites Gastrointestinal bleeding Jaundice Hypertension Motility disorders of the GI tract Differential diagnosis of chest pain Edema, cyanosis, dyspnea Approach to patients with bleeding problems Differential diagnosis of anaemias and lymph node enlargements Hematuria, edema Syncope Genetic disorders, obesity

PRACTICE (total 16 hrs) Medical thinking, general principles of differential diagnostics Differential diagnostics of diarrhea and constipation Differential diagnostics in patients with abdominal pain Differential diagnostics of ascites Differential diagnostics of occult and manifest gastrointestinal bleedings Differential diagnostics of jaundice Differential diagnostics of the gastrointestinal motility disorders differential diagnostics of hypertension differential diagnostics of chest pain and syncope differential diagnostics of edema, cyanosis, dyspnoe differential diagnostics of anaemias and lymph node enlargement

differential diagnostics in patients with renal diseases selected differential diagnostic problems, consultation selected differential diagnostic problems, consultation


123

MEDICAL PSYCHOLOGY II. 7th semester

*

LECTURE/PRACTICE (1 hr/week, 1 hr/week) Lecture: 1. Introduction. Outline of the course 2. Medically unexplained symptoms – Somatisation 3. Risk behaviors and problem health conditions 4. Psychological aspects of general practice and family medicine 5. Cardiovascular diseases. Psychological aspects of prevention, treatment and rehabilitation 6. 7. 8. 9. 10. 11. 12. 13. 14.

*

Cancer prevention and the care of cancer patients The psychological aspects of death and dying. Breaking bad news Surgery and organ transplantation. Problems of body-image in different medical conditions The role of persuasive communication and suggestion in medicine Psychological interventions and communication in pediatric care Management of communication problems and medical decision making Telemedicine and the use of the internet in health communication Psychological interventions /Short introduction to psychotherapies I Psychological interventions /Short introduction to psychotherapies II

Practice: 1. Psychosocial factors and family background as causes of morbidity and health risks 2. Communication with relatives and friends of the patient. Problems with referring patients to psychiatrist, psychologist 3. Communication with aggressive patient 4. Psychological aspects of helping chronic patients. Patients in crisis 5. Breaking bad news 6. Difficulties in the medical team-work. The drawbacks of hierarchy

NEUROLOGY 9th semester

*

* * * * * * *

LECTURE (1 hr/week) a. Introduction. History of neurology. b. Physical examination. Neurological status. a. The organization of the sensory system. b. Pain. The organization of the motor system. Spinal cord. Neurological localization. Brainstem. Neurological localization. Cerebellum. Neurological localization. Cerebral cortex. Frontal lobe. Neurological localization. Temporal lobe. Neurological localization.

PRACTICE (2 hrs/week) Neurological investigation related to the lecture

Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture

124 *

* * * *

*

a./ Parietal and occipital lobes. Neurological localization. b./ Vegetative nervous system. Cerebrospinal fluid. Diagnostic methods. Neurovascular system. Neurological localization. Extrapyramidal system. Neurologicallocalization. a./ Electrical activity and examination of muscles and nerves b./ Modern neuroradiological diagnostic methods. Review of basic neurology knowledge

Neurological investigation related to the lecture

Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture


10th semester

* * * * * * * * * * * * *

LECTURE (1 hr/week) Cerebrovascular disorders I. Cerebrovascular disorders II. Epilepsies. Epilepsies. Sleep disturbances. Muscle and motoneuron disorders. Neuroinflammatory disorders. Multiple sclerosis Extrapyramidal disorders I. Extrapyramidal disorders II. Intensive neurology. Tumors of the central nervous system. Neurorehabilitation. Diagnosis and treatment of headaches. Pathomechanism of neurodegenerative disorders. Dementias. Neurology in general medical practice. Novel therapies in neurology.

PRACTICE (1 hr/week) Neurological investigation related to the lecture Neurological investigation related to the lecture Neurological investigation related to the lecture

Neurological investigation related to the lecture Neurological investigation related to the lecture



OBSTETRICS AND GYNAECOLOGY 7th semester

*

*

*

LECTURE (3 hrs/week) Introduction. Concepts of obstetrics and gynaecology and its role in modern medicine. Historical review. Development and function of the placenta. Development of the fetus. Endocrinology of pregnancy.

PRACTICE (2 hrs/week) Prenatal care. Obstetrical history, physical examination.

Pregnancy tests

Induction of labour

Curriculum 2014/2015 * * *

* * * * *

* * * * * * * * * * * * * *

Obstetrical anatomy. Diagnosis of pregnancy. Genital and extragenital changes during pregnancy. Signs of the fetal life. The mature placenta, umbilical cord, membranes and amniotic fluid. Intrauterine position of the fetus. Antenatal care and examinations. Normal mechanism of labour. Patient care during labour.

125 Ultrasonography Follow up examinations during pregnancy Genetics, CVS, AC, Cordocentesis

Preparation for labour CTG, OCT, AS, X ray Normal delivery Induced abortion. Surgical aspects. Forceps delivery, vacuum extraction

Pharmacokinetics in pregnancy. Registration of the uterine activity. Diseases of the trophoblast. Breech presentation Monitoring of the fetus and Postpartal hemorrhage placenta. Physiology of the uterus. Caesarean section Obstetrical ultrasonography. The newborn. Care and management. The puerperium. Abortion. Ectopic pregnancy. EPH-gestosis. Breech presentation and delivery. Multiple pregnancy. Premature labour. Management of delivery. Induction of labour. Intrauterine death. Postmaturity. Dysmaturity. Alternative delivery methods.

8th semester LECTURE (3 hrs/week) Uterine rupture, postpartal haemorrhage, abnormal puerperium.

PRACTICE (2 hrs/week) Gynaecological history taking, physical and pelvic examinations.

*

Causes of 3rd trimester bleeding (premature separation of the placenta, DIC, plac. praevia). Dysmaturity. Hyperemesis.

*

Erythroblastosis fetalis.

* *

Dystocia (difficult labor) pelvic dystocia due to uterine dysfunction, dystocia of fetal origin, dystocia of placental origigin. Infectious diseases and pregnancy.

* * *

Respiratory, renal, neurologic, endocrine and metabolic diseases. Benign tumors of the uterus. Diseases of the cervix. Cancer screening.

Screening methods for cervical cancer: cytology. Screening methods for cervical cancer: colposcopy. Curettage, cervical biopsy, electrocauterisation, conisation. Female infertility, diagnostic procedures. Infertility study of the male partner. Labor procedures of infertility. Conception control. Endoscopy.

* *

126 * * * * * * * * * * * * * * * *

Pelvic inflammatory diseases. Diseases of the Fallopian tube. Medical complications during pregnancy. (Heart, haematologic, gastrointestinal diseases.) Genetic disorders. Birth control. Contraception. Abnormalities of the menstruation. Climacteric. Ethical aspects of Obstetrics-Gynaecology. Endometriosis. Assisted fertilization in the female. Gynaecological endoscopy. Infertility of the female. Benign ovarian tumors. Malignant ovarian tumors. Adolescent gynaecology. Infertility of the male. Diseases of the vulva and vagina.

Abdominal gynaecological operations. Vaginal surgical procedures. Adolescent gynaecology. Physiotherapy in gynaecology. Radio- and chemotherapy. Psychosexual diseases.

OPHTALMOLOGY 10th semester

* * * * * * * * * * * * * *

LECTURE (2 hrs/week) The eye and systemic diseases Essentials of anatomy and physiology, Optics and refraction The lids and the lacrimal system, The conjuctiva The cornea, The lens The iris, The choroid The retina The vitreous, Retinal detachment Optic nerve diseases, Neuroophthalmology Strabismus, The child with suspected eye disease Glaucoma, The Sclera, the orbita Acute painless visual disturbance, Chronic loss of vision Chronic ocular unease, The acute red eyes Ocular injuries Ophthalmology through on the world

PRACTICE (2 hrs/week) General Practical General Practical General Practical Angiography and laser therapy Pediatric ophthalmology Contact lens Ultrasound in ophthalmology Elektrophysiology MTO Eximer laser surgery General Practical General Practical General Practical General Practical

ORTHOPAEDICS 7th semester

*

*

* *

* *

LECTURE (2 hrs/week) Field of orthopaedics, history. Diagnosis and treatment of orthopaedic disorders. Disorders of the spine in childhood. Scoliosis. General affections of the skeleton Congenital deformities and disabilities Disorders of the foot (congenital club foot, pes planovalgus) Arthritis, osteomyelitis, tuberculous arthritis Bone tumors

PRACTICE (2 hrs/week) The course of the examination of the patients with locomotor system diseases. Diagnostic means. X-ray demonstration. Case report. Examination of the neck and cervical spine. Disorders of the neck and cervical spine. X-ray demonstration. Case report. Examination of the trunk and spine. Disorders of the trunk and spine. X-ray demonstration. Case report. Examination of the scoliosis. Diagnostic means. X-ray demonstration. Case report. Examination of the shoulder and elbow. Disorders of the shoulder and elbow. X-ray demonstration. Case report. Examination of the forearm, wrist and the hand. Disorders of the forearm, wrist and the hand. X-ray demonstration. Case report. Examination of the hip regio. Disorders of the hip. Messuring the


* * *

*

* *

127 length of the limbs. X-ray demonstration. Case report. Examination of the osteoarthritis of the hip and of the knee. X-ray demonstration. Case report.

Infections and degenerative disorders of the spine. Spondylolysis, spondylolisthesis. Disorders of the neck and Examination of the knee. Disorders of the knee. X-ray demonstration. upper limbs Case report. Congenital dislocation and Examination of the leg, ankle and foot. Disorders of the leg, ankle dysplasia of the hip and foot. X-ray demonstration. Case report. Other hip disorders in Infections of the bone. Arthritis. Bone tumors. X-ray demonstration. childhood (Perthes disease, Case report. slipped upper femoral epiphysis. Transient arthritis of the hip.) Osteoarthritis of the hip. Osteoarthrosis. General affections of the skeleton. (Neurological Idiopathical necrosis capitis disorders). X-ray demonstration. Case report. femoris. Disorders of the knee. Neuromuscular diseases, general affections of the skeleton

OTO-RHINO-LARYNGOLOGY 9th semester

*

LECTURE (2 hrs/week) Oto-rhino-laryngology in medicine.

* *

History of oto-rhino-laryngology. Anatomy and physiology of the ear.

*

Diseases of the external ear and their treatment.

*

Acute inflammation of the middle ear.

*

Complications of acute otitis media.

*

Non-suppurative diseases of the middle ear.

*

Chronic otitis media. Complications of chronic otitis media.

*

Reconstruction of the hearing mechanism.

*

Anatomy of the inner ear. The vestibular and cochlear system.

*

Examination of hearing and the vestibular system.

PRACTICE (3 hrs/week) Examination equipment in otorhino-laryngology. Practice in use of forehead mirror and ear speculum. Examination of the external auditoy meatus and eardrum. Practice in cleaning the external meatus. Diseases of the external meatus. Ear drops. Examination of the Eustachian tube. Demonstration of eardrum perforations and various ear diseases. X-ray, CT, MR pictures of the ear. Examination of hearing by means of tuning forks. Measurement of hearing loss. The usual method of recording hearing by audiometer. Demonstration of various types of pure-tone audiograms. Hearing aids. Demonstrations of otoneurological examinations. Clinical examination of the nose and nasal cavity. Practice in using nasal speculum. Posterior rhinoscopy. Demonstration of diseases of nasal cavity. Treatment of nasal injuries.

128 *

*

Diseases of the inner ear: toxic damage to the ear, inflammatory and vascular lesions of the inner ear. Acoustic trauma. Meniere's disease. Diseases of the inner ear: acoustic neuroma, temporal bone fractures.

*

Anatomy of the nose and nasal sinuses.

*

Diseases of the external nose and the nasal cavity.

*

Sinusitis. Treatment and complications. Fractures of the sinuses.

*

Haemorrhage from the nose. Tumors of the nose and paranasal sinuses.

*

Anatomy of the pharynx. Diseases of the nasopharynx.

*

Adenoid hyperplasia. Benign and malignant nasopharyngeal tumors. Acute and chronic inflammatory diseases of the pharynx. Acute and chronic tonsillitis. Peritonsillar abscess and complications. Indications of tonsillectomy. Tumors of mesopharynx. Functional anatomy of the larynx. Acute and chronic diseases of the larynx. Injuries of the larynx. Paralysis of the larynx. Tumors of the hypopharynx and the larynx. Classifications of malignant laryngeal tumors. Treatment of laryngeal tumors. Diseases of the oesophagus and the inferior respiratory tract. Differential diagnosis of neck nodes.

* * * * * * * * * *

Haemorrhage from the nose. Treatment of epistaxis.. Demonstration of Bellocq pack. Treatment of sinusitis. Nasal drops. X-ray, CT, MR pictures of nasal sinuses. Demonstration of puncture of the maxillary sinus. Differential diagnosis of headache. Examination of the mouth and pharynx. Demonstration of pharyngeal diseases. Demonstration of tumors in the larynx and hypopharynx. Examination of the larynx. Demonstration of laryngeal diseases. Anaesthesia in otorhino-laryngology. Demonstration of patients after tracheostomy. Cleaning of tracheostomy tube. Demonstration of esophagoscopes and bronchoscopes. The method of introducing the naso-esophageal nutrition tube. Differential diagnosis of neck nodes in practice.

PEDIATRICS 9th semester

* * * *

*

LECTURE (3 hrs/week) The ill child and his doctor

PRACTICE (2 hrs/week) History taking, Iatrogenic infections The interview, The problems, Mortality Examination of the child and infant, Rickets, tetany Genes Newborn, preterm and small for dates infants Chromosomes and chromosome abnormalities, Common autosomal O2, incubator, mechanical abnormalities, Common sex chromosome abnormalities, Single ventillation gene (Mendelian) inheritance, Multifactorial (polygenic) inheritance, Recent advances in molecular genetics, Genetic counselling Fetus Paediatric surgery: malformations


* *

* * * *

* * * *

* *

*

*

* *

* *

Periconceptional medicine, The placenta, Examination of the fetus, Drugs which cross the placenta, Fetal transplacental infections, Infections acquired during passage through the birth canal, Maternal immunoglobulins Newborn

129 Developmental and nutritional state

Healthy babies' care and nutrition Prevention and treatment of infections

Routine examination of the newborn, Birth injuries, Birth asphyxia, Size at birth, Respiratory problems in the newborn, Jaundice in the newborn, Gastrointestinal problems, Neural tube anomalies, Cleft lip and palate, Neonatal infections, Neonatal convulsions and jitters Nutrition Immunological procedures, tuberculin test Breast feeding, Artificial feeding, Feeding problems, Nutritional Management of the poisoned deficiencies, Malnutrition, Obesity child Infection Treatment of burns, shock, unconsciousness Measles, Rubella, Mumps, Chicken pox (Varicella), Herpes simplex Respiratory tract diseases, infections, Glandular fever, Kawasaki disease (mucocutaneous Asthma, Allergens and lymph node syndrome), Erythema infectiosum (5th disease), respiratory function testing Roseola infantum (Exanthema subitum), Hand, foot and mouth disease, Hepatitis A (infectious jaundice), Poliomyelitis, Diphtheria, Pertussis (whooping cough), Scarlet fever, Tuberculosis, Malaria, Human immunodeficiency virus, Immunisation, Immune deficiency Hazards Examination: murmurs, heart failure, congenital heart disease Injuries, Burns and scalds, Drowning, Choking, Poisoning, Other Cardiological diagnostics hazard Airways and lungs Dehydration, Infusion therapy, Malabsorption, Liver diseases Upper respiratory tract infections, Upper airway obstruction, Lower Paediatric surgery: appendicitis, respiratory tract infections, Cystic fibrosis, Asthma inguinal hernias and disorders of the testes Heart Diagnosis and treatment of UT, renal diseases Acyanotic lesions with a left to right shunt, Atrial septal defect Emergency treatment, (Ostium secundum), Atrial septal defect (Ostium primum), resuscitation, intensive care Ventricular septal defect, Patent ductus arteriosus, Pulmonary hypertension, Obstructive lesions, Aortic stenosis, Coarctation of the aorta, Hypoplastic left heart, Pulmonary stenosis, Cyanotic heart disease, Fallot tetralogy, Transposition of the great arteries, Cardiac arrhythmias, Subacute bacterial endocarditis, Rheumatic fever, Hypertension Hyperlipoproteinaemia Gut Blood and bone marrow diagnostics, anaemia, bleeding disorders, Transfusion Acute abdominal pain, Recurrent abdominal pain, Gastroenteritis, Malabsorption, Chronic diarrhoea, Intestinal parasites, Constipation, Liver disease, Liver enzyme deficiencies Urinary tract and testes Renal function tests, Urinary tract malformations, Urinary tract infections, Haematuria, Acute nephritic syndrome, Nephrotic syndrome, Renal tubular disorders, Acute renal failure, Chronic renal failure, The testes, The prepuce Blood Iron deficiency anaemia, Aplastic anaemia, Haemolytic anaemias, Bleeding disorders

10th semester

130

* *

* * * * * * * * * * * * * * * *

LECTURE/PRACTICE (2 hrs/week, 2 hrs/week) Malignancy The management of children with cancer, Acute leukaemia, Lymphomas, Neuroblastoma, Brain and spinal tumors, Soft tissue sarcomas, Renal tumors, Germ cell tumors, Bone tumors, Other tumors, Histiocytic disorders Growth Head growth, Height and weight, Short stature, Excessive height Endocrine Puberty, Disorders of sexual differentiation, Adrenal glands, Thyroid, Parathyroid glands, Diabetes, Hypoglycaemia Skin Rashes of early infancy, Atopic eczema, Infections and infestations, Congenital skin lesions, Other common skin disorders Bone and joint Arthritis, Osteomyelitis, Normal postural variations, Scoliosis, Hip disorders, Knee disorders, Talipes (clubfoot), Genetic bone and joint disorders, Bone tumors and allied disorders Brain, cord, nerve, muscle Intracranial infection, Encephalitis, Epilepsy and convulsions, Neuromuscular disorders, Headache, Ataxia, Cerebral palsy Vision, hearing, speech Hearing, Speech and language Mental handicap The identification and treatment of mentally handicapped children, Mentabolic and other cerebral degenerative disorders, Specific treatment and general management Emotions and behavior Brain disorders, The interaction between the child and his world, Behavioral problems, Emotional disorders, Management, The maltreatment of children

PHARMACOLOGY 7th semester

* * *

LECTURE (3 hrs/week) Introduction into pharmacology. Pharmacokinetics I: Absorption. Passage across body membranes. Pharmacokinetics II: Distribution.

*

Pharmacokinetics III: Elimination - Metabolism and excretion. Individual drug responses: Pharmacogenetics. Allergy. Age, diet, and diseases. Safety and effectiveness. Therapeutic index. Development of new drugs. Tolerance and drug dependence. Drug interactions. Autonomic nervous system: Introduction. Ganglion stimulants, inhibitors. Cholinomimetics. Cholinolytic drugs. Sympathomimetic drugs. Alpha-adrenoceptor blockers. Beta-adrenoceptor blockers. Adrenergic neuron blocking agents. Peripheral muscle relaxants. Antihistamines. Serotonin, kinin, PG, LT antagonists. Smooth muscle relaxants. Treatment of asthma bronchiale.

*

Local anaesthetics. Antiinflammatory drugs. Glucocorticoids.

*

Chemotherapy I. Cell wall synthesis inhibitors. Protein synthesis inhibitors. Chemotherapy II. Sulfonamids. Kinolones. Anthelmintic agents. Antiseptics, desinfectants.

* * * * *

*

PRACTICE (2 hrs/week) Receptor theory. Computer Lab: Drug-receptor interactions. Computer Lab: Pharmacokinetics.

Computer Lab: Repeated drug administration. MTO: General pharmacology. MTO-GPH Discussion Computer Lab: Parasympathetic nervous system. Computer Lab: Sympathetic nervous system. Computer Lab: Skeletal muscle and smooth muscle relaxants. MTO: Autonomic nervous system. MTO: Autonomic nervous system - Discussion. Prescripton writing.


131

Chemotherapy III. Macrolid-antibiotics. Chemotherapy of neoplastic Treatment of mycobacterium diseases. infections (TBC). Chemotherapy IV: Antiviral and antifungal agents. Treatment of To recapitulate: Chemotherapy. protozoon infections (malaria).

8th semester

* * * * * * * * * *

LECTURE (4 hrs/week) Psychostimulants. Anorectics. Hallucinogenics. Anxiolytics. Sedatohypnotics. Pharmacology of general anaesthesia. Opioid analgetics. Antidepressants. Antiparkinson drugs. Central muscle relaxants.

* * *

Antipsychotic drugs. Antiepileptic drugs. Antiarrhythmic drugs. Antianginal drugs. Diuretic drugs. Pharmacotherapy of hyperlipoproteinemias. Cardiotonics. Antihypertensive drugs. Drugs acting on the blood. Stroke (prevention and treatment). Diabetes mellitus. Hyperthyreosis. Hormones. Vitamines. Drugs that influence the GIT. Toxicology I. Toxicology II.

*

Toxicology of doping.

PRACTICE (2 hrs/week) Introduction. Contemporary drug abuse. To recapitulate: General anaesthesia. Pharmacotherapy of pain. To recapitulate: CNS MTO: CNS. Therapy of AMI. Computer lab - CVS Therapy of migraine. Therapy of anaemias. MTO: CVS. Discussion - CVS. Principles of immunopharmacology. Prepare for the final exam.

PSYCHIATRY 9th semester

* * * * * * * * * * * * * *

LECTURE 1 hr/week The psychiatric examination Psychodynamic aspects of mental disturbances Psychopathology of perception and affect Pathology of cognitive and psychomotor functions Biological foundation of psychiatry Principles of social psychiatry Behavioural approach to psychiatry Genetic and neurochemical concepts in psychiatry Affective (mood) disorders: depression Mania and bipolar affective disorders Cyclothymia and dysthymia Clinical aspects of schizophrenia Etiology and therapy of schizophrenia Paranoid disorders

PRACTICE 1hr/week Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture

132 10th semester LECTURE (2 hrs/week) Organic mental disorders Dementia states Psychoactive substance abuse Psychosomatic diseases Psychosexual disorders Personality disorders Anxiety states. Neurosis I. Anxiety states. Neurosis II. Psychotherapeutic methods Psychopharmacologic treatments Child and adolescent psychiatry Sleep disorders Geriatric psychiatry Ethics and law in psychiatry

* * * * * * * * * * * * * *

PRACTICE (1 hr/week) Psychiatric patient Psychiatric patient Psychiatric patient Psychiatric patient Psychiatric patient Psychiatric patient Psychiatric patient Psychiatric patient Psychiatric patient Psychiatric patient

examination examination examination examination examination examination examination examination examination examination

related related related related related related related related related related

to to to to to to to to to to

the the the the the the the the the the

lecture lecture lecture lecture lecture lecture lecture lecture lecture lecture

Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture Psychiatric patient examination related to the lecture

PUBLIC HEALTH 7th semester LECTURE *

*

*

*

*

*

*

(2 hrs/week) (2 hrs/week) The history of preventive medicine and public health. The levels of prevention. Requirements of the semester. The global health situation; priorities in global health. Measuring health status of a population; the theoretical basis of demography. Introduction into public health and The theoretical basis of epidemiology. demography. Demographic indexes and their use. Measuring mortality. Analysis of statistical Health status of high-risk populations data-bases. Epidemiological indexes and (elderly people, prisoners, military and their use, epidemiological studies: cross homeless people). sectional and case-control studies. Epidemiological studies: cohort and Epidemiology of chronic diseases – interventional studies. Planning and cardiovascular diseases. preparation of epidemiological surveys. Students’ presentations. Practical aspects of the prevention of Epidemiology of chronic diseases – cardiovascular diseases. Students’ tumors. presentations. The role of screening in the prevention of Epidemiology of chronic diseases – selected chronic diseases. Students’ metabolic and musculoskeletal diseases. presentations. Practical aspects of the prevention of Epidemiology of chronic diseases – selected chronic conditions. Students’ gastrointestinal and respiratory diseases. presentations.

*

HOLIDAY

*

Epidemiology of mental disorders, suicide and accidents. Epidemiology of health care associated infections (infection control, nosocomial surveillance).

*

PRACTICE

General epidemiology of infectious diseases. Sterilization, disinfection (hand hygiene), disinsection, deratisation. Practical aspects of vaccination. Students’ presentations.


*

*

*

Epidemiology of infectious diseases: airborne diseases. Epidemiology of infectious diseases: enteric diseases, toxicoinfections. Epidemiology of infectious diseases: hematogenic, cutaneous, and sexually transmitted diseases. Epidemiology of infectious diseases: zoonoses and transmissible spongiform encephalopathies

133 Practical aspects of the prevention of selected infectious diseases I. Case studies. Practical aspects of the prevention of selected infectious diseases II. Case studies. Practical aspects of the prevention of selected infectious diseases III. Case studies. Consultation

PUBLIC HEALTH 8th semester

*

*

LECTURE

PRACTICE

(2 hrs/week)

(2 hrs/week) Requirements, questionnaire. Basics of nutrition, measuring nutritional status.

Health influencing factors – life style, environment, health care, genetics. Nutrition in public health. Malnutritions. Diet-related chronic diseases.

* Food quality and safety. * Epidemiology of smoking. *

*

*

*

Epidemiology of alcohol and drug consumption.

Dietary guidelines, healthy nutrition. Treatment of obesity. The role of diet in the prevention of dietrelated diseases; special dietary requirements of certain chronic diseases I. (Students’ presentations) The role of diet in the prevention of dietrelated diseases; special dietary requirements of certain chronic diseases II. (Students’ presentations) Smoking cessation guidelines for health professionals.

Role of physical activity in the prevention of chronic diseases. Human ecology; global warming; air pollutants and their effects on human health (indoor and outdoor). Water pollutants and their effects on human health. Sewage, soil pollutions, waste management.

Health promotion in various settings (community, workplace, school)

General toxicology. Toxicology of metals, solvents and gases.

Case studies about health effects of certain chemicals.

Environmental epidemiology: examining health damaging effects of air pollution Environmental epidemiology: examining health damaging effects of surface and drinking water pollution.

*

Toxicology of persistent organic pollutants, Practical aspects of occupational health. plastics and agrochemicals.

*

Occupational health. Occupational safety, accident prevention. Occupational diseases caused by physical exposures Occupational diseases caused by biological, ergonomic and psychosocial exposures. Health effects of dusts, occupational pneumoconiosis.

*

*

*

Health effects of workplace-related exposures. Occupational hazards in health care (case studies). Visiting factory.

Structure and operation of health systems I. – general aspects

Quality improvement in health care. Quality improvement methods according to steps of PDCA.

Structure and operation of health systems II. – health and health care in the family

Consultation.

134 (mother, infant, child, adolescent, elderly).

PULMONOLOGY 7th semester

*

LECTURE (1 hr/week) Main clinical features of lung diseases COPD (Chronic bronchitis.Emphysema.) Respiratory function. Spirometry. Pharmacospirometry. Provocation. Asthma bronchiale

* *

Malignant neoplasm of lung Pneumonia lung abscess

*

Breathing mechanics. Blood gases. Interstitial lung diseases Diseases of pleura

* * * *

* * * * * *

Pulmonary thromboembolism, cor pulmonale chronicum Tuberculosis Occupational lung diseases. Fungal infections. Respiratory failure. Sleep apnoea syndrome.

PRACTICE (2 hrs/week) Morphology and roentgen anatomy of lung. Physical examination. Characteristic X-ray findings. Chronic bronchitis. "Pink puffers" and "blue bloaters". Lung function tests. Pharmacospirometry. Diagnosis of asthma bronchiale. Aspecific provocation tests, skin test, IgE. Bronchoscopy, Thoracoscopy, mediastinoscopy. Radiographic findings of lung cancer. Transthoracic needle-biopsy. Cytology. TNM classification. Radiographic findings of pneumonia. Sputum examination. Treatment. Pletysmography. Diffusing capacity. Cardiopulmonary exercise test. Aetiology of pleural effusions. Aspiration of the pleural effusion. Laboratory findings. X-ray findings in tuberculosis. Sputum examination in tuberculosis. Tuberculin test. Treatment. Cor pulmonale. Differential diagnosis of disseminated lung diseases.

RADIOLOGY 7th semester

*

* * * * * *

*

* * * * *

LECTURE (1 hr/week) Imaging diagnostics: role, development, present and future Conventional radiology Contrast agents Ultrasound Computed tomography and magnetic resonance imaging Interventional radiology Gastroenterology I.(esophagus, stomach, duodenum) Gastroenterology II. (mesenteric small bowels large intestine) Joints Bones Chest I. (lung) Chest II. (mediastinum) Heart and peripheric vessels

PRACTICE (1 hr/week) Imaging diagnostics: role, development, present and future

Conventional radiology Contrast agents Ultrasound Computed tomography and magnetic resonance imaging Interventional radiology Gastroenterology I.

Gastroenterology II.

Joints Bones Chest I. (lung) Chest II. (mediastinum) Heart and peripheric vessels


Head and neck

135 Head and neck

8th semester

* * * * *

* * * * * * * *

LECTURE (1 hr/week) Radiology of the Radiology of the Radiology of the Radiology of the

breasts and female reproductive system liver biliary tract pancreas & spleen

PRACTICE (1 hr/week) Radiology of the breasts Radiology of the liver Radiology of the biliary tract Radiology of the pancreas & spleen Neuroradiology I.

Neuroradiology I. (image modalities, congenital anomalies and vascular lesions of the head) Neuroradiology II. Neuroradiology II. (Tumours, infections, trauma of the head) Neuroradiology III. Neuroradiology III. (Spinal diseases) Pediatric radiology Pediatric radiology Radiology of the kidneys & the urinay tract Radiology of the kidneys & the urinay tract Radiology of the retroperitoneal space Radiology of the retroperitoneal space Radiology of the pelvis and the male reproductive organs Radiology of the pelvis and the male reproductive organs Radiological aspects of emergency Radiological aspects of emergency Radiological aspects of trauma Radiological aspects of trauma

STOMATOLOGY 7th semester

* * * * * * * * * * * * * *

LECTURE/PRACTICE (1 hr/week, 2 hrs/week) Disorders of development of the teeth and related tissues dental caries preventation Diseases of dental pulp, and treatment of dental caries Periapical periodontitis and severe infections Extraction of teeth and related problems. Injuries to teeth and supporting tissues Periodontal diseases Cysts of the maxillo-facial region Oral diseases Systemic diseases in relation to dentistry Benign tumors, praecancerous lesions Malignant tumors Maxillo-facial traumatology Prosthetic dentistry and disorders of temporomandibular joints Treatment of malignant tumors Rehabilitation following maxillo-facial-surgery

SURGERY 7th semester

*

LECTURE (2 hrs/week) Benign of the breast

PRACTICE (2 hrs/week) The syllabus of the practicals are synchronized with the lectures.

*

Surgery of the breast cancer

The patients examinations and the discussion of the symptoms and illnesses follow the topics of the lectures.

136 * * * *

Surgery Surgery Surgery Surgery

* * *

Vascular surgery Cardiac Surgery Test

of of of of

the the the the

abdominal wall mediastinum thorax lung cancer

The practicals take place in the Department of Surgery.

8th semester

* *

LECTURE (2 hrs/week) Surgery of the pancreas I. Surgery of pancreas II.

*

Benign diseases of the oesophagus * The malignant disease of oesophagus * Gastric surgery. Malignant disease * Gastric surgery. Benign disease * Surgery of gallbladder and biliary ways * Surgery of the liver * Surgery of the spleen * Bleeding of the GI tract * Benign diseases of the colon and rectum * Malignant diseases of the colon and rectum * Proctology, the care of patients wearing of intestional stoma * Test 9th semester

* *

LECTURE (1 hr/week) Endocrine surgery I. Endocrine surgery II.

* * * * * * *

Ileus Peritonitis Appendicitis Minimal invasive surgery Surgerical immunology Organ Transplantation Test

PRACTICE (2 hrs/week) The syllabus of the practicals are synchronized with the lectures. The patients examinations and the discussion of the symptoms and illnesses follow the topics of the lectures. The practicals take place in the Department of Surgery.

PRACTICE (1 hr/week) The syllabus of the practicals are synchronized with the lectures. The patients examinations and the discussion of the symptoms and illnesses follow the topics of the lectures. The practicals take place in the Department of Surgery.

TRAUMATOLOGY 10th semester LECTURE (2 hrs/week)



*

* *

*

*

*

*

*

*

*

*

* *

137

General traumatology. Injuries of soft tissues. Types of fractures. Bone bealing. Methods of managing fractures. Early and late complications of the fractures and dislocations.

Clinical examination of the injured patient. Additional clinical investigations. X-ray examination. Fractures and dislocations about the shoulder, humerus and elbow. Principles of fracture treatment. First aid. Treatment of uncomplicated closed fractures. Fractures of the olecranon, radius and ulna. General hand surgery. Plaster technique. Synthetic Fractures and dislocations of the hand. splinting. Other external splints. Surgical management of soft tissue injuries. Treatment of tendon Operative treatment of fractures. injuries. Skin ijuries. Treatment of skin defects. Plastic Presentation of cases. reconstructive surgery of the hand. Injuries of the peripheral nerves. Nerve degeneration and Complications of fractures. regeneration. Microsurgical treatment of peripheral nerve injuries. Delayed union. Non-union. Amputations. Replantation, revascularisation and microvascular Avasular necrosis. Osteoarthritis. plastic surgical methods. Reflex sympathetic dystrophy. Injuries of the vertebral column with and without neurological Joint injuries. Dislocation and spinal cord defect. Surgical stabilization of the vertebral fractures. subluxation. Diagnosis, complications, treatment. Head injuries. Fractures, epidural, subdural and intracerebral Head injuries. Diagnosis, hematomas. First aid diagnosis and treatment. treatment. Visit at the intensive care unit. Fractures of the hip joint, intracapsular fractures of the femoral Spine injuries. Cervical spine head. Intertrochanteric fractures. Fractures of the femur and injuries. Halo-thoracic support. patella. Paraplegia and tetraplegia. Pelvic injuries. Fractures of the acetabulum. Examination of the Shoulder, upper arm and elbow knee joint. Injuries of the knee joint. Ligamentous injuries. injuries. Meniscal ruptures. Arthroscopy of the knee joint. Sport traumatology. Fractures of the tibial condyles. Closed and open injuries of the Forearm, wrist and hand. tibial shaft. Complications. Fractures and soft tissue injuries. Fractures and dislocations about the ankle and foot. Peripheral nerve injuries. Microsurgical treatment. Brachial plexus injuries. Politraumatization and multiple injuries. First aid and Plevic fractures. Fractures of the transportation. Priorities in polytrauma. Primary and secondary femoral neck. Intertrochaenteric treatment of fractures. fractures. Treatment of the femoral fractures. Thoracic and abdominal injuries. Treatment of open and blunt Knee injuries. Arthroscopy. traumas. Intensive therapy of injured patients. Meniscal tear. Rupture of ACL. Leg, ankle and foot injuries. Methods of treatment. Special fractures in children.

UROLOGY 10th semester

*

* * * * *

LECTURE (1hr/week) Signs and symptoms urological diseases. Case history and the physical examination. Congenital anomalies. Urolithiasis. Incontinency. Urotraumatology. Acute and chronic renal failure.

PRACTICE (2hrs/week) Case history, physical examination. Case presentation.

Signs and symptoms of the urology patient. Case presentation. Catheters and endoscopic instruments. Endoscopy. Percutaneous epicystostomy and nephrostomy. ESWL.

138 * * * * * * * *

Nonspecific infections in the urology. Tumors of the kidney and ureter. Tumors of the bladder. Tumors of the external male genitalia. Tumors of the prostate. BPH. Acute urology. Consultation

Uro-radiology. Physical examinations of patients. Laboratory investigations in the urology. Biopsy from bladder, prostate and testis. Evaluation of sonography. Physical examinations. Case reports. Visit to operating theatre. Acute urology

DOCTOR-PATIENT COMMUNICATION 7th or 8th semester The aim of the subject: Students attain the skills needed for doctor-patient consultation and for selecting from the appropriate consultation models. By the end of the course students will be aware of the importance of doctor-patient communication and its critical points. They should acquire the ethical principles of doctor-patient communication and they should be able to integrate them into their consultation behaviour. Students should know the ethical and communication methods of commitment to providing medical information. They should be able to carry out a 10-minute doctor-patient consultation, and afterwards to analyse and evaluate their performance from the video recording at a group meeting. They should be able to elaborate a medical case. HUNGARIAN LANGUAGE 7th semester

* * * * * * * * * * * * * * *

PRACTICE (3 hrs/week) Gynaecology. The external and internal female genital organs. Revising the Possessive Structure. The most frequent complaints and diseases in the field of gynaecology. Practising basic doctor-patient situations: role-play, history taking in Gynaecology. Asking the patient about her menstruation cycle and history. Revision of Wh-questions. Obstetrics. Taking history concerning previous pregnancies. Deliveries and abortions. Complaints during pregnancy. Patient examination at the Department of Obstetrics and Gynaecology. General and specific instructions to patients. Sending the patient for further investigations. Practising basic doctor-patient situations: role-play, history taking in Obstetrics and Gynaecology. Revising the Indefinite Pronouns. Practising doctor-patient communication: role-play, history taking and giving advice to patients concerning treatment and medication. Urology. The most common conditions and diseases in the field of Urology: cystitis, kidney stones, pyelonephritis. Patient examination in Urology. Giving instructions and sending the patient for further investigations. Revising Adverbs of Manner. Practising doctor-patient situations: role-play, history taking in Urology. Briefing English case histories taken from the field of Urology in Hungarian. Final tests (written and oral). Pulmonology. The structure of the respiratory system. Revising the name of body parts. The most frequent abnormal conditions and diseases in Pulmonology. Revising the vocabulary of breathing problems, coughing and sputum. History taking, patient examination and specific instructions in the field of Pulmonology. Practising doctor-patient communication: role-play, history taking and examination of patients with respiratory problems. Giving advice to patients concerning medication. Reading simple Hungarian case histories taken from the field of Pulmonology and Urology.

8th semester


* * * * * * * * * * * *

* *

139

PRACTICE (3 hrs/week) Neurology. Parts of the nervous system. Revising Time Clauses. Some diseases of the nervous system. Most frequent patient complaints at the Neurology Department. Symptoms and signs of certain neurological conditions. History taking and patient examination in Neurology. Giving specific instructions to patients. Mid-term test. Practising doctor-patient communication at the Neurology Department: role-playing history taking and discussing possible treatment methods with the patient. Revising the Conditional Mood. Briefing simple English case histories taken from the field of Neurology in Hungarian. Final exam practice: written. Final exam practice: oral. Paediatrics. Locomotor, cognitive, emotional and social development. The most important milestones. Paediatrics. Asking the child’s parents about symptoms and signs. Giving advice concerning treatment options. Revising the Auxiliary Verbs. The most common paediatric problems. Discussing and arguing with parents. Revising vocabulary in connection with delivery and breast feeding. Acute cases in the field of paediatrics. Interviewing parents presenting their child with accidents, meningitis or febrile convulsion. Management of acute cases. Practising doctor-patient communication: role-play, history taking and giving advice to patients’ parents concerning treatment and medication. Reading simple Hungarian case histories taken from the field of Paediatrics. Explaining medical procedures and giving advice to patients. General revision. Practising doctor-patient dialogues in all covered medical fields. Revision. Practising doctor-patient situations that can emerge at medical and surgical departments. Interviewing and examining patients, sending them for further investigations, giving advice on diet, life style and medication. Final test.

ADVANCED BIOSTATISTICS 8th, 10th semester

* *

* *

* *

* * *

* *

LECTURE (1 hr/week) Introduction: summary of basic biostatistics Nonparametric methods for two ore more dependent or independent data Multiple linear regression, linear models Comparison of several independent group-means: two-way ANOVA Two-way ANOVA with interaction Comparison of several related group-menad: repeated measures ANOVA Summary Diagnostic tests. Specificity, sensitivity, PPV, NPV, Accuracy Biostatistical methods in epidemiology, relative risk, odds ratio Logistic regression: equation, use, meaning Logistic regression: ogisticc accuracy ROC curve

PRACTICE (1 hr/week) The mean concepts of ogisticccs. Statistical computer systems. The choice of the appropriate statistical method and its evaluation

Data sets with several independent variables (i.e., risc factors) Data sets and problems when two-way ANOVA is appropriate

Understanding the concept of interaction Data sets and problems for repeated measurements ANOVA

TEST I: solving two problems, main results and interpretation Calculation of the diagnostic measures Calculation of RR and OR by hand and by computer. Comparison of methods. Simple logistic regression problem soving by computer program Examples from the medical literature: the use of ogistic regression to find risc factors of an illness.

140 * * *

Multivariate methods: discriminant analysis Multivariate methods: cluster analysis Summary

Examples from the medical literature: decision making by computer Examples from the medical literature: classification of cases or variables TEST II: solving two simple problems, main results and interpretation.

BASIC BIOSTATISTICS 7th, 9th semester

*

* *

* *

* * *

*

*

*

* * *

LECTURE ( 1 hr/week) Data definition, types of data, displaying data. Sample characteristics. Probability, random variables and their types, distributions. Binomial, Poisson, uniform and normal distribution and their properties. Statistical estimation, confidence intervals. Testing hypotheses, significance. One-sample ttest. Paired and Independent samples t-tests. Errors in hypothesis tests Comparing the mean of several gourps: one-way analysis of variance. Relationship between continuous variables, correlation, linear regression. Relationship between categorical variables: the chisquare test for independence The use of 2x2 tables in diagnostic tests. The chisquare-test for goodness of fit. Nonparametric methods. Summary Examples from the literature

PRACTICE (1 hr/week) Bar chart, histogram. Calculation of the mean and standard deviation.

Calculation of ogisticccs. The use of a computer program. The use of statistical tables – standard normal distribution.

Calculation of the confidence interval for a population mean. The use of the t-table. Practice of one-sample t-test using experimental data.

Practice of t-tests using experimental data. The meaning of significance, p-value. TEST I. Independent t-tests and one-way ANOVA. Multiple comparisons.

Scatterplot, trend-line in EXCEL. http://www.ruf.rice.edu/~lane/stat_sim/reg_by_eye Evaluation of a 2x2 table by hand calculation and by computer

Calculation of sensutitvity, specificity, positive and negative predictive value. Statistical tests on ranks. TEST II. Practical questions of applied biostatistics.

CASES IN CLINICAL MICROBIOLOGY 8th or 10th semester

* *

* * *

LECTURE (2 hrs/week) How to take samples for microbiology? Cases will be discussed where these procedures have a great influence on the outcome of the laboratory investigations and the fate of the patient. Upper and lower respiratory infections. Causative agents in different age groups. Cases will be discussed with community-acquired and nosocomial pneumonia. How to select appropriate antibiotic treatment empirically? The value of microbiological tests. Upper and lower urinary tract infections. Differences in antibiotic resistance of pathogens causing urinary tract infections. Pitfalls in the laboratory tests. Differences in gastrointestinal diseases caused by bacteria, viruses and parasites. The possibilities of the laboratory diagnosis and treatment Infection or colonization. How to distinguish them through laboratory tests? Cases caused by fungi will


*

*

*

*

*

*

*

*

be discussed. Systemic or local fungal infections? Difficulties in laboratory tests Nosocomial infections. Nosocomial epidemics. Which methods are suitable to diagnose the spread of nosocomial pathogens in a hospital environment? Cases involved in nosocomial epidemics will be discussed, together with the measures that can be taken to stop the spread of nosocomial pathogens. Neuroinfections and joint infections. The main pathogens causing these kind of infections, and how to diagnose them will be discussed. Direct and indirect methods to reach a microbiological diagnosis and special aspects in the selection of antibiotic treatment will be discussed through the cases. Infections of immunosuppressed patients. Special aspects of infections of haematology patients will be discussed . The role of facultative and non-pathogenic bacteria in infections of immunosuppressed patients and the problems in the laboratory diagnosis of such clinical situations will be discussed through the cases. Sexually transmitted diseases and their consequences. Classical and newly recognized sexually transmitted infections (STI) and sexually transmitted diseases (STD). Diagnostic possibilities. Sexual abuse of children and adolescents. How to choose antibiotic treatment? How can we recognise HIV infected and AIDS patients. Cases caused by STI and STDs. Infections caused by anaerobic bacteria. Diagnostic problems and how to take samples to be able to isolate anaerobic pathogens will be discussed? Special aspects of clostridial infections as well as cases where anaerobic bacteria were involved will be discussed together with the special aspects of antibiotic treatment of such cases. Sepsis and its consequences. How blood culture techniques help in the diagnosis of sepsis. Determination of false-positive and false-negative blood cultures and the sensitivity and specificity of this technique will be discussed through clinical cases. Treatment options selecting the best antibiotic should be determined. Antibiotics. How to use antibiotics in prophylaxis and in treatment? The spread of antibiotic resistance worldwide, in different countries, and in hospitals/wards. Development of resistance to special antibiotics during patient therapy. Cases demonstrating the consequences of the correct and incorrect choice of antibiotics during treatment will be discussed How to take samples in virus infections? Which laboratory tests can help in their diagnosis? Cases caused by viruses and their differential diagnostics will be discussed. Emerging and re-emerging viral infections. Prevention and treatment of viral infections. Possibilities of antiviral therapies. How to use molecular biological methods in routine clinical microbiological diagnostics? The value of these methods? Quality control problems. Cases will be discussed where molecular techniques can be helpful in the diagnosis. Cases caused by parasites and their clinical diagnosis and laboratory detection will be discussed

CHILD AND ADOLESCENT PSYCHIATRY 8th or 10th semester

* * * * * * * * * * * * * * * * * * * *

LECTURE (2hr/week) Introduction Assessment, formulation Classification Psychological examinations Normal child development, risk and protective factors in childhood psychiatric disorders Conduct disorder Juvenile delinquency, School non-attendance Hyperactivity / ADHD Emotional disorders: Anxiety disorders I. Separation anxiety, Generalized anxiety Anxiety disorders II. Specific phobias, Social anxiety, Panic disorder Anxiety disorders III. PTSD Anxiety disorders IV. OCD Affective disorders Cognitive Behavior Therapy for depression-PASCET Suicide and deliberate self- harm Pervasive developmental disorders Psychoses of childhood and adolescence Eating disorders Enuresis Encopresis,

141

142 * * * * * * * * * *

Tic disorders, Tourette’ syndrome Selective mutism Behavior therapy-case presentation (SM) Speech and learning disorders Mental retardation Psychosomatics disorders-Recurrent abdominal pain, chronic fatigue syndrome, conversion disorder The child and adolescent in hospital Maltreatment of children Consultation Exam

CLINICAL GENETICS AND CLINICAL GENOMICS 10th semester

* * * * * * * * * * * * * *

LECTURE (2 hrs/week) Genetics in medicine. Human genome, epigenome. Genome programs, postgenomic era. Epigenetic control of gene expression. Genomic imprinting, X chromosome inactivation, tissue specific imprinting. Teratogenesis. Teratogens in clinical praxis. Reproductive genetics. Prenatal genetic screening. Prenatal genetic diagnostics. Fetal programming. Dominant and recessive pattern of inheritance in clinical praxis. Chromosome anomalies in clinical practice. Dysmorphology. Facial dysmorphism. Genetic counseling, genetic screening. Ethical considerations. Genetic law. Local aspects in EC, U.S. and Hungary Genetics therapy. Stem cell therapy. Artificial chromosome. Pharmacogenetics, pharmacogenomics. Cancer genetics and genomics. Mitochondrial inheritance. Multifactorial inheritance. Genetic background of complex diseases, geneenvironment interactions. Clinical Genomics. Changing paradigm in common disease. The significance of genomic knowledge in the diagnosis, therapy and prevention of human diseases. Summary. Assessment of the semester.

CLINICAL IMMUNOLOGY 8th, 10th semester

* * * * * * * * * * * * *

LECTURE (2 hrs/week) The structure and the functions of the immune system. The biological significance of the self recognition. Methods for clinical immunological investigations. Immune-mediated tissue damage. The role of cytokines. Immunology of allergic diseases. Autoimmunity - Health and disease. The autoimmune diseases. Immunhaematology. Connective tissue disorders and joint diseases. Organ specific autoimmune diseases. Detection of histocompatibility antigens and their pathogenetic significance. Transplantation immunology. Reproductive immunology. Immundeficiencies. The immunology of HIV infection. Tumor immunology. Neuroimmunology. Immune manipulation.

CLINICAL PHARMACOLOGY 8th or 10th semester LECTURE (2 hrs/week)

Curriculum 2014/2015 * * * * * * * * * * * * * *

Introduction into clinical pharmacology. Historical background. The basic principles of pharmacokinetics. The basic principles of pharmacodynamics The basic principles of pharmacogenetics. Drug interactions and side-effects. The basic principles of biostatistics. The evaluation of preclinical data. The principles of GCP (Good Clinical Practice) The ethical and authorative legislation of clinical drug trials. The principles of human phase studies (Phase I-II.) The principles of human phase studies (Phase III-IV.) Bioequivalence studies. Industrial drug research and development. Visit to the human Phase I. Unit at the I. Dept of Internal Medicine.

INTRODUCTION TO AVIATION AND SPACE MEDICINE 7th or 9th semester * * * * * * * * * * * * *

The history, subject, position and role of aviation and space medicine in medical sciences. The effects of short- and long-range flights from the passenger's point of view. The basics of aerodynamics. The composition, layers and main physical properties of the atmosphere. Pressure oxygen breathing. Motion sickness in aviation. The adverse effects of changes in baropressure on the human body. The effect of reduction in partial oxygen pressure on the human body, its importance in aviation. The pilots' lifestyle, nutrition and sports. The medical qualification of pilots and parachuters. The psychophysiological characters of the pilot's personality. The fatigue and overload of aircrews. The effect of the dynamic factors of aviation on the pilot's body. The ergonomical characters of the cockpit of an aircraft. The pressurized cabin. The pilot's life-saving equipments. The effects of noise and vibration on the human body during flight. Spatial alertness in flight, flight illusions. The physiological effects of space flight on the human body. The basic principles of astronaut selection and training. Decompression sickness

THE CLINICAL BASICS OF AVIATION AND SPACE MEDICINE 8th or 10th semester * * * * * * * * * * * * *

The aeromedical qualification system in civilian and military practice. Functional diagnostic examinations in practical aviation medicine. Aeromedical problems in pulmonology and gastroenterology. The cardiological aspects of aviation medicine. Excess temperature in aviation. Neurological and psychiatricalproblems in aviation medicine. Ophtalmology in aviation medicine. Emphasized aeromedical issues in oto-rhino-Iaryngology. The comparison of experiences gained in the MiG-29 and the Gripen. The issues of alcoholism in aviation medicine. Rheumatological aspects of aviation. The medical background of the International Space Station (ISS). Medical care during long-term space flights. Energy drinks in aviation?

143

144 LABORATORY DIAGNOSTICS: USE OF LABORATORY TESTS IN PRACTICE 8th, 10th semester TUTORIAL (2 hours/week): Solving and discussing clinical cases * * * * * * * *

* * *

* * *

Introduction to laboratory diagnostics Visit at the Department of Laboratory Medicine Acid-base balance disorders: diagnosis and treatment of acute cases, combined acid-base disorders, discussion of complex cases Disorders of water, sodium and potassium balance: diagnosis and treatment of osmoregulatory defects and hypo-, and hyperkalaemia and -natraemia Bone and calcium metabolism: Causes of hypo- and hypercalcaemia, diagnostic algorithms Laboratory diagnosis of renal diseases: Managing patients with acute and chronic renal failure, diagnosis of impaired glomerular and tubular function. Differential diagnosis of proteinuria Laboratory diagnosis of diabetes mellitus: diagnosis and treatment of acute cases, problems with the laboratory monitoring of long-term outcomes Cardiovascular risk assessment and laboratory management of patients with cardiovascular diseases: case discussions – Evidence-based practice of AMI, acute coronary syndrome and congestive heart failure. Differential diagnosis of acute chest pain and dyspnoea. The role of laboratory in oncology: tumor markers and their use in practice Case presentations in endocrinology – a case oriented approach: Functional tests and diagnostic algorithms in the investigation of endocrine abnormalities Laboratory diagnosis of coagulation disorders: Cases on the diagnosis of thrombo-embolic events (DVT, PE, congenital thrombophilias, lupus anticoagulant and anti-phospholipid syndrome) and bleeding disorders Haematology cases: differential diagnosis of anaemia, diagnosis of monoclonal gammopathies, use of flow cytometry in haemato-oncology Therapeutic drug monitoring: Role of TDM in patients treated with lithium, digoxin, antibiotics and immunosuppressive medications. Toxicology: Cases on drug overdose and ingestion of toxic substances.

NEUROSURGERY 10th semester

*

LECTURE (1 hr/week) Introduction to neurosurgery. History, main topics, diagnostic procedures. Head injury. Head trauma, biomechanics, skull fractures, early and late complications, management, outcome. Tumors of the CNS. Increased intracranial pressure, brain oedema, signs and symptoms of space-occupying lesions. Supratentorial tumors.

*

Axial-tumors, tumors of the posterior fossa.

*

Tumors of the spine and spinal cord, metastatic tumors.

*

Vascular disorders of the brain. Pathophysiology of cerebral circulation, occlusive cerebrovascular diseases, operative versus conservative treatment, intracerebral haemorrhage. Subarachnoid bleeding, cerebral aneurysms, early and late surgery, arteriovenous malformations cavernomas of the brain, venous anomalies. Spinal trauma. Biomechanics, acute pathology, early and late surgery versus conservative treatment, peripheral nerve injuries. Cervicobrachial syndromes. Herniation of the intervertebral disc in the cervical region, cervical spondylosis, narrowed spinal canal, surgical versus conservative therapy.

* * *

*

* *

PRACTICE (1 hr/week) Material of the practice. Material of the practice. Material of the practice. Material of the practice. Material of the practice. Material of the practice. Material of the practice.

lectures in lectures in lectures in lectures in lectures in lectures in lectures in

Material of the lectures in practice. Material of the lectures in practice. Material of the lectures in practice.


*

Lumbar syndromes. Low back pain, lumbar disc prolaps, spondylosis of the lumbar region, failed back syndrome. Congenital anomalies. CSF circulatory disturbances, hydrocephalus, meningoceles, Chiari-malformation, pediatric neurosurgery. Main topics of functional neurosurgery

*

Exam

*

NUCLEAR MEDICINE 7th semester

*

*

*

*

* *

*

*

*

*

*

LECTURE (1 hr/week) Nuclear medicine physics History Basic principles of nuclear physics and radiation biology Instrumentation of nuclear medicine Radiation detector systems Gamma camera Single photon emission computed tomography Positron emission computed tomography (PET), PET/CT Radiopharmacology Tracer principle Production of radionuclides Radiopharmaceutical chemistry Nuclear medicine in disorders of bones and joints Bone scintigraphy Joint scintigraphy Bone marrow scintigraphy Complementary investigations of the bones and joints Nuclear cardiology I. Myocardial perfusion studies Nuclear cardiology II. Radionuclide ventriculography (RNV) at rest RNV during stress ECG-gated RNV with SPECT Miscellaneous nuclear cardiological methods Nuclear medicine investigations of the respiratory system Lung perfusion investigation Lung ventilation investigations Diagnosis of pulmonary embolism Nuclear medicine in gastroenterology Hepatobiliary scintigraphy Differential diagnostics of focal liver lesions Scintigraphy of the salivary glands Oesophagus passage study Gastric motility study Gastrointestinal bleeding site detected by radioisotopes Meckel's diverticulum detection Investigations of intestinal inflammations Investigations in malabsorption (Schilling test) In vitro nuclear medicine assays with radionuclides Principles of immunoassays Clinical applications of immunoassays Endocrinological aspects of nuclear medicine Thyroid scintigraphy Parathyroid scintigraphy Adrenal scintigraphy Neuroendocrine tumor imaging techniques Nuclear medicine in urogenital disorders Static renal scintigraphy

145 Material of the lectures in practice. Material of the lectures in practice. Material of the lectures in practice.

146

*

*

*

Dynamic studies Vesicoureteric reflux study Evaluation of renal transplants Scrotum scintigraphy Radionuclide hysterosalpingography Nuclear medicine of the central nervous system (CNS) Brain angioscintigraphy and blood-brain barrier scintigraphy Cerebrospinal fluid scintigraphy Brain SPECT studies Neuroreceptor SPECT Brain tumors evaluated by SPECT Brain PET studies Nuclear oncology Tumour markers Tumouraffin radiopharmaceuticals and their applications Oncological aspects of bone marrow scintigraphy Scintigraphy of the lymphatic system, sentinel lymph node detection Oncological aspects of PET, PET/CT and SPECT/CT studies Nuclear medicine in therapy Thyroid disorders treated with radioisotopes Radiosynovectomy Palliative treatment of bone metastases Possibilities in radioimmunotherapy Neuroendocrine tumours treated with 131-I-MIBG 32-P treatment in polycythaemia vera

ORAL AND MAXILLOFACIAL SURGERY 8th and 10th semester LECTURE (2 hrs/week) 04 Sept. Cardiac risk patients in dental practice 11 Sept. Antibiotics in dentistry and oral surgery 18 Sept. Internal medicine questions in dental practice 25 Sept. Dental treatment of patients with bleeding disorders 02 Oct. Dental treatment of patients following radio/chemotherapy 09 Oct. Maxillary sinus diseases and their management 16 Oct. Stomato-oncological screening 30 Oct. Differential diagnosis of neck masses 6 Nov. Differential diagnosis of facial pain 13 Nov. Head and neck skin tumors 20 Nov. Odontogenic tumors 27 Nov. Sedoanelgesia 4 Dec. Written exam

Prof. József Piffkó Dr. Renáta Varga Prof. Judit Méray Dr. Zoltán Raskó Dr. Renáta Varga Dr. Zoltán Raskó Dr. Róbert Paczona Dr. Róbert Paczona Dr. Róbert Paczona Prof. József Piffkó Dr. Renáta Varga Prof. József Piffkó Dr. Renáta Varga

SOCIAL AND HEALTH POLICY 8th, 10th semester LECTURE (2 hrs/week) * * * * * * * *

Introduction to health policy. The influence of international organisations (WHO, World Bank etc.) on national health policies. Health and health policy in the European Union. The basic principles of health care systems. Health care services in selected European countries. Health care services in North American countries. Quality assurance in health care. Human resource management in health care. Introduction to social policy. The aim and task of social policy. The basic values and principles of social policy.

* * * * * *

Curriculum 2014/2015 Social policy in welfare states. The structure and function of social policy in the European Union. Social policy in developing countries. Poverty, deprivation, patterns of inequalities. Social policy of high-risk populations I. (immigrant, ethnicity, unemployed). Social policy of high-risk populations II. (disabled, chronic diseased, elderly). The evaluation of the social and health care reforms from the beginning of ’90s – world tendencies (Final evaluation).

THE LANGUAGE OF EFFECTIVE DOCTOR-PATIENT COMMUNICATION I. 7th or 9th semester

*

PRACTICE (2 hrs/week) An introduction to physician – patient communication 1

*

An introduction to physician – patient communication 2

*

Gastroenterology 1

*

Gastroenterology 2

*

Gynecology and obstetrics 1

*

Gynecology and obstetrics 2

*

Orthopedics

*

Endocrinology

* *

Surgery 1 Surgery 2

*

Surgery 3

*

Pulmonology

*

Dental care

*

Test/exam

An overview of communication. Identifying the elements that make up communication The patient centered approach: patient friendly language in history taking, instructing patients during examinations and discussing treatment options. Receiving patients: greeting them and putting them at ease. Introducing yourself as the attending physician and explaining your role. The presenting complaint. Encouraging patients to describe their problems in their own words. Asking for history of menstruation Encouraging withdrawn patients to speak Taking obstetric history: previous pregnancies, complications, deliveries, asking for present complaints Patient’s past medical history. Discussing family medical history. Taking effective notes during the interview. Explaining medical terminology to a patient Updating patient notes Giving results: explaining results to patients, giving a prognosis Planning surgical treatment: explaining treatments/ surgical interventions to a patient, discussing options Describing benefits and side effects, negotiating treatment Informed decision making Delivering bad news Writing concise and accurate notes Preparing and reassuring the patient during the examination. Negotiating the treatment.

THE LANGUAGE OF EFFECTIVE DOCTOR-PATIENT COMMUNICATION II. 8th or 10th semester

* *

PRACTICE (2 hrs/week) Cardiology Anesthesiology and intensive care

*

Oncology

*

Dermatology

Enquiring about patient’s social history. Asking about life-style and environmental health Anesthesiological assessment of a patient Describing types of anesthesia Postoperative care Educating and counseling patients and their families Revision of the written documentation of patient care Discussing treatment options Showing sensitivity and respect to patients

147

148 *

Pediatrics 1

*

Pediatrics 2

*

Psychology

* *

Neurology 1 Neurology 2

*

Rheumatology

*

Oto-rhino-laryngology

*

Ophthalmology

*

Urology

*

Test/exam

Communicating with children and adolescents. Establishing and developing rapport with a child. Reassuring a child. Child-friendly instructions. Asking about substance use. Encouraging withdrawn patients to speak. Calming aggressive or angry patients. Reassuring a patient or relative. Showing empathy. Techniques for communicating with patients with neurological problems. Language to show sensitivity. Encouraging patients to express their fears and concerns. Giving a prognosis. Summarizing and structuring the interview Communicating with elderly patients Handling complaints Managing unrealistic requests (saying no) Encouraging patients to express their fears and concerns Advising on lifestyle

TROPICAL DISEASES 8th or 10th semester LECTURE (2 hrs/week) * General aspects of tropical diseases. Characteristic diseases of the gastrointestinal tract focusing on bacterial infections frequently seen in tropical areas. Pathogenesis, clinical and laboratory diagnostics, and therapeutic options. Travelers’ diarrhea. * Diarrhea caused by protozoa: entamoebiasis, cryptosporidiasis, giardiasis, and diseases caused by Isospora, Balantidium, and Capillaria. Pathogenesis, clinical and laboratory diagnosis, and therapy. * Arthropod-borne infections caused by various bacteria, rickettsia, and spirochetes in tropical areas. Distribution of various vectors which may influence the emergence of a disease. Plague, tularaemia, endemic typhus, spotted fevers, and ehrlichiosis, etc. Clinical and laboratory diagnosis, and therapy. * Tuberculosis, leprosy, and other bacterial infections with special emphasis on tropical areas. (meningitis caused by N. meningitidis, anthrax, tetanus, and rhinoscleroma). Clinical and laboratory diagnosis. Differences in clinical picture in the tropical areas compared to other countries. Therapy. * Special aspects of viral infections in tropical areas. Geographical distribution, pathogenesis, clinical and laboratory diagnosis of arboviruses. Pathogenesis, clinical and laboratory diagnosis of viral hemorrhagic fevers; Marburg and Ebola viruses. Importance of the early diagnosis of imported viral infections in non-tropical countries. * SARS, avian flu, rabies, West Nile virus- and other rare viral infections characteristic in some tropical countries. Slow viruses. Clinical picture, pathogenesis, and diagnostic possibilities. * Malaria, schistosomiasis. Causative agents, distribution of vectors, pathogenesis, clinical and laboratory diagnosis, and therapy. * Leishmaniasis, and trypanosomiasis (Chagas' disease). Clinical symptoms, epidemiology, pathogenesis, and laboratory diagnosis. * Soil-transmitted helminths. Epidemiology, life cycles clinical and laboratory diagnosis. Therapy. * Sexually transmitted infections and diseases. Differences in the presentation of various bacterial and viral STDs in tropical areas. Pathogenesis, clinical and laboratory diagnosis. AIDS in Africa and in other undeveloped countries. Clinical symptoms, epidemiology, laboratory diagnosis, and therapy. AIDSrelated infections and therapy. * Special non-infectious diseases in tropical areas. Hemoglobinopathies, thalassemias, sickle cell anemia. Malnutrition in childhood and in adults. Kwashiorkor disease. Anemia. Venomous bites and stings. Snake bite. Special aspect of respiratory infections in tropical area. Cumulation of infections, local epidemics, and pandemics. New viral infections caused respiratory diseases. Newly discovered viruses caused serious diseases in tropical and non-tropical area. Case discussions of diseases frequently seen in tropical areas or in patients having journeys in tropical areas, with active involvement of the students in solving the diagnostic and/or therapeutic problems 1. Laboratory seminar with demonstration of diagnostic procedures in the Institute of Clinical Microbiology 1. RHEUMATOLOGY

Curriculum 2014/2015 9

th

semester LECTURE (2 hrs/week) The course „Rheumatology” covers the whole spectrum of musculoskeletal diseases including the immune-mediated internal medical systemic inflammatory diseases. The aim of the course is to provide a more detailed and practical overview of various types of arthritis and systemic autoimmune diseases, in addition to the limited topics covered within the clinical immunology section of the Internal Medicine course. The immunological basis of the diseases, novel treatment paradigms, the principles of immunosuppressive therapy, the innovative biological therapies, and the systematic diagnostic work-up of patients with arthritis, and other immune-mediated manifestations, such as Raynaud’s phenomenon, skin, renal, pulmonary, neurological, etc. involvements typical of systemic autoimmune diseases are detailed within the course „Rheumatology”. The topics are delivered in lectures and practicals at the Department of Rheumatology.

*

Introduction into rheumatology (basics, history, immunopathological principles)

*

Rheumatoid arthritis – therapeutic principles, new paradigms, biological therapies

*

Systemic lupus erythematosus, antiphospholipid syndrome.

*

Practical

*

Systemic sclerosis (scleroderma), Mixed connective tissue disease (MCTD).

*

Systemic vasculitides (terminology, general overview of the clinical spectrum)

*

ANCA-associated vasculitides

*

Polymyalgia rheumatica, giant cell arteritis, Takayasu arteritis

*

Practical

*

Spondyloarthritides (ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathicarthritis)

*

Consultation

CARDIAC ELECTROPHYSIOLOGY AS A BASIC PROPERTY OF CARDIAC FUNCTION 4th and 8th semester

* * * * * * * * * *

LECTURE AND PRACTICE (2 hrs/week) Introduction. Basic principles of electrophysiology, the impulse propagation in the heart I. Basic principles of electrophysiology, the impulse propagation in the heart II. The action potential of myocytes and the ionic channels determining the action potential I. The action potential of myocytes and the ionic channels determining the action potential II. Methods and techniques in cardiac electrophysiology. Electro-mechanical coupling in the heart I. Genetic background of ion-channel disturbances in the heart. Electro-mechanical coupling in the heart II. The mechanism of developing cardiac arrhythmias

149

150 * * * *

Electrophysiological changes after the disturbances in blood supply to the myocardium. Experimental methods and clinical relevance to investigate cardiac arrhythmias. Investigational techniques in cardiac cellular electrophysiology Practical and consultation


151

Faculty of Dentistry

152 GENERAL INFORMATION REGARDING THE CREDIT SYSTEM AT THE FACULTY OF DENTISTRY STRUCTURE OF STUDIES CURRICULUM 9002AK_N_2013 For the complete suggested study plan visit the ETR website. Students have to acquire a total of 300 credits 5 modules in order to obtain the Doctor of Dental Medicine diploma. All the requirements of a module have to be fulfilled in order to enter the next module: • acquisition of the required credits • completion of Criteria Subjects: 2 semesters of Physical Training (It is compulsory to complete it in the first year) Dentist-Patient Communication (in the 5th semester) Preclinical Course of Prosthodontics and Gnathology Examination (in the 6th semester) Prosthodontics and Implantology (in the 10th semester) Operative Dentistry and Endodontics (in the 10th semester) Pediatric Dentistry and Orthodontics (in the 10th semester) Oral Surgery (in the 10th semester) Periodontology (in the 10th semester) Summer practices 8 semesters of Hungarian Language 1 semesters of Latin Language for Dental Students MODULES: 1. Basic Module (years 1-2, semesters 1-4) In the Basic Module one has to acquire a minimum of 80 credits in order to enter the Pre-Clinical module. It is recommended to acquire 100 credits according to the following scheme: • • • •

Compulsory Subjects: 80 credits Compulsory Elective Subjects: 10 credits recommended in the basic module Elective Subjects : 6 credits recommended in the basic module Criteria Subjects (summer practice in Nursing, summer practice in Odontotechnology , 4 semesters of Hungarian Language) It is compulsory to complete 2 semesters of Physical Education in the first year.

2. Pre-Clinical Module (year 3, semesters 5-6) In the Pre-Clinical Module one has to acquire a minimum of 52 credits in order to enter the Clinical Module. It is recommended to acquire 60 credits according to the following scheme: • • • •

Compulsory Subjects: 52 credits Compulsory Elective Subjects: 5 credits recommended in the preclinical module Elective Subjects: 3 credits recommended in the preclinical module Criteria Subjects (Dentist-Patient Communication, Preclinical Course of Prosthodontics and Gnathology Examination, 2 semesters of Hungarian Language, Dental Surgery Summer Practice )

4. Dental Clinical Module (year 4, 5 semesters 7-10) In the Dental Clinical Module one has to acquire a minimum of 83 credits 5. General Clinical Module (year 4, 5 semesters 7-10) In the General Clinical Module one has to acquire a minimum of 25 credits

Curriculum 2014/2015 • •

153

Criteria Subjects (summer practice in Basic Treatment in Dental Medicine , 2 semesters of Hungarian Language, Prosthodontics and Implantology, Operative Dentistry and Endodontics, Pediatric Dentistry and Orthodontics, Oral Surgery, P Periodontology)

6. Compulsory Elective Subjects One has to acquire a minimum of 25 credits until the 10th semester. 7. Elective Subjects One has to acquire a minimum of 15 credits until the 10th semester. 8. State Board Examination A student is entitled to sit for the State Board Examination if he/she has fulfilled all the study and examination requirements of the Dental Medicine Program. In order to certify the completion of the ten-semester education period of the Dental Medicine Program, student has to fulfill all the study and examination requirements according to the Curriculum by obtaining minimum 280 credits. The thesis has to be submitted and defended in the 10th semester. The credit number obtained at a successful defense of the thesis is 20 credits. Conditions of issuing the Diploma of Major of Dental Medicine: Obtaining minimum 300 credits Completion of all parts of the State Board Examination: - Successful defense of the thesis -completion of the written test, the practical and the oral part of the patient examination

STRUCTURE OF STUDIES CURRICULUM 9002AK_N For the complete suggested study plan visit the ETR website. Students have to acquire a total of 300 credits 5 modules in order to obtain the Doctor of Dental Medicine diploma. All the requirements of a module have to be fulfilled in order to enter the next module: • acquisition of the required credits • completion of Criteria Subjects: 2 semesters of Physical Training (It is recommended to complete it in the Basic Module) Dentist-Patient Communication (in the 5th semester) Preclinical Course of Prosthodontics and Gnathology Examination (in the 6th semester) Prosthodontics and Implantology (in the 10th semester) Operative Dentistry and Endodontics (in the 10th semester) Pediatric Dentistry and Orthodontics (in the 10th semester) Oral Surgery (in the 10th semester) Periodontology (in the 10th semester) Summer practices 8 semesters of Hungarian Language 2 semesters of Latin Language

154

MODULES: 1. Basic Module (years 1-2, semesters 1-4) In the Basic Module one has to acquire a minimum of 84 credits in order to enter the Pre-Clinical module. It is recommended to acquire 100 credits according to the following scheme: • • • •

Compulsory Subjects: 84 credits Compulsory Elective Subjects: 10 credits recommended in the basic module Elective Subjects : 6 credits recommended in the basic module Criteria Subjects (summer practice in Nursing, summer practice in Odontotechnology , 4 semesters of Hungarian Language) It is recommended to complete 2 semesters of Physical Education in the Basic Module.

2. Pre-Clinical Module (year 3, semesters 5-6) In the Pre-Clinical Module one has to acquire a minimum of 46 credits in order to enter the Clinical Module. It is recommended to acquire 54 credits according to the following scheme: • • • •

Compulsory Subjects: 46 credits Compulsory Elective Subjects: 5 credits recommended in the preclinical module Elective Subjects: 3 credits recommended in the preclinical module Criteria Subjects (Dentist-Patient Communication, Preclinical Course of Prosthodontics and Gnathology Examination, 2 semesters of Hungarian Language, Dental Surgery Summer Practice )

4. Dental Clinical Module (year 4, 5 semesters 7-10) In the Dental Clinical Module one has to acquire a minimum of 85 credits 5. General Clinical Module (year 4, 5 semesters 7-10) In the General Clinical Module one has to acquire a minimum of 25 credits • •

Criteria Subjects (summer practice in Basic Treatment in Dental Medicine , 2 semesters of Hungarian Language, Prosthodontics and Implantology, Operative Dentistry and Endodontics, Pediatric Dentistry and Orthodontics, Oral Surgery, P eriodontology)

6. Compulsory Elective Subjects One has to acquire a minimum of 25 credits until the 10th semester. 7. Elective Subjects One has to acquire a minimum of 15 credits until the 10th semester. 8. State Board Examination A student is entitled to sit for the State Board Examination if he/she has fulfilled all the study and examination requirements of the Dental Medicine Program. In order to certify the completion of the ten-semester education period of the Dental Medicine Program, student has to fulfill all the study and examination requirements according to the Curriculum by obtaining minimum 280 credits. The thesis has to be submitted and defended in the 10th semester. The credit number obtained at a successful defense of the thesis is 20 credits.


155

Conditions of issuing the Diploma of Major of Dental Medicine: Obtaining minimum 300 credits Completion of all parts of the State Board Examination: - Successful defense of the thesis -completion of the written test, the practical and the oral part of the patient examination II. PRECONDITIONS FOR ENROLLMENT TO THE FOR THE COMING SEMESTERS: CURRICULUM 9002AK_N •

The compulsory courses in the second semester have examination requirements. This means one can take the examination of the second semester course only if the examination of the first semester subject (defined in the examination requirement) has been completed successfully: Course Anatomy, Histology and Embryology II. Medical Chemistry II. Medical Physics and Statistics II. Cell Biology and Molecular Genetics II.

Examination requirement Anatomy, Histology and Embryology I. Medical Chemistry I. Medical Physics and Statistics I. Cell Biology and Molecular Genetics I.

The first semester courses can be taken as examination courses in the second semester. This means that the student will be exempted from fulfilling the study requirements (classes do not have to be attended). An examination course can be taken only once in a certain subject. The fee of the course is 570 USD. If one fails to complete an examination course both the study and examination requirements have to be completed in the proper semester (the whole course has to be repeated). •

The compulsory courses in the third semester have subject requirements. This means one can attend a third semester course only if the examination of the second semester (defined in the subject requirement) has been completed successfully: Course Anatomy, Histology and Embryology III. Biochemistry I.

Subject requirement Anatomy, Histology and Embryology II. Medical Chemistry II.

In this case the failed examination of the second semester can be repeated as an examination course in the semester when it is offered by the Department concerned.

•

The compulsory courses in the fourth semester have examination requirements. This means one can take the examination of the fourth semester course only if the examination of the third semester (defined in the examination requirement) has been completed successfully: Course Anatomy, Histology and Embryology IV. Biochemistry II. Physiology for dental students II.

Examination requirement Anatomy, Histology and Embryology III. Biochemistry I. Physiology for dental students I.

Further conditions of requirements are in the complete study plan visit the ETR website.

156

COMPULSORY PRACTICES IN SUMMER

Students who intend to perform the compulsory summer practice abroad should have a “Letter of acceptance” issued by the hospital where the student wishes to complete the practice has to be presented at the Foreign Students’ Secretariat. Deadline for presenting it: May 06, 2014. Official detailed certificate on the accomplishment of the practice has to be submitted subsequently, otherwise students cannot register for the next semester. Fees if the practices are spent in Hungary: The fee for Nursing practice is 500 USD, for Odontotechnology is 600 USD, for Oral Surgery practice is 600 USD and for Basic Treatment in Dental Medicine is 800 USD. Practice fee must be paid before starting the practice. Practices are spent in Hungary (Deadline for presenting the application: March 31, 2014.): 1st year dental students have to perform a practice in Nursing of two weeks. Faculty of Dentistry: Department of Oral Surgery Period of time: from July 7, 2014 to August 1, 2014

2nd year dental students have to perform a practice in Odontotechnology of two weeks. Faculty of Dentistry: Department of Prosthodontics and Oral Biology Period of time: from July 7, 2014 to August 1, 2014

3rd year dental students have to perform a practice in Oral Surgery of four weeks. Faculty of Dentistry: Department of Oral Surgery Period of time: from July 7 2014 to August 29, 2014

4th year dental students have to perform a practice in Basic Treatment in Dental Medicine of four weeks. Faculty of Dentistry: Department of Prosthodontics and Oral Biology and Department of Operative and Esthetic Dentistry Period of time: from July 7, 2014 to August 01, 2014

158

Credit

Course Requirement (SR=Subject requirement; ER=Examinatio n requirement)

FOG-MA011

Anatomy for Dental Students 1

Department of Anatomy


2

-

Examination

2

-

FOG-MA012




-

2

Term Mark (5)

1

-

FOG-MA111

Biology for Dental Students 1

Department of Oral Biology and Experimental Dental Research

Prof. János Minárovits

2

-

Examination

2

-

FOG-MA112



1

-

Evaluation (5)

1

-

FOG-MA081

Physics for Dental Students 1


2

-

Examination

2

-

FOG-MA082



1

-

Evaluation (5)

1

-

FOG-MA101

Chemistry for Dental Students 1

Prof. Gábor Tóth

2

-

Examination

2

-

Term Mark (5)

2

-

Term Mark (5)

2

-

Course Code

Course

Department and Head of Department

Hrs/week: Theory Hrs/week: Practice

Form of exam

SUGGESTED STUDY PLAN for 9002AK_N_2013 Study Plan

DENTISTRY BASIC MODULE (semesters 1-4) 2014/2015 1st year fall, 1st semester Compulsory Subjects

Department of Oral Biology and Experimental Dental Research Department of Oral Biology and Experimental Dental Research Department of Oral Biology and Experimental Dental Research Department of Medical Chemistry

FOG-MA102


Department of Medical Chemistry

Prof. Gábor Tóth

-

FOG-MA071

First Aid and Resuscitation

Department of Traumatology

Prof. Endre Varga

-

Total 30 2

Dr. Emil Segatto

1

-

Evaluation (5)

1

-

Dr. Emil Segatto

-

1

Term Mark (5)

1

-

FOG-MA061

Introduction to Dentistry

FOG-MA062

Introduction to Dentistry

Department of Orthodontics and Pediatric Dentistry Department of Orthodontics and Pediatric Dentistry

Criteria Subjects FOG-MA221

Latin Language for Dental Students

Department of Foreign Languages

Dr. Éva Demeter

-

2

Signature

0

-

FOG-MA231

Hungarian Language 1


Dr. Éva Demeter

-

4

Term Mark (5)

0

-

XT0011-PHE

Physical Education*

Sport Center


-

2

Signature

0

-

Compulsory Elective Subjects FOG-MAC011

Introduction to Medicine

Dept.of Behavioural Sciences


1

-

Evaluation (5)

1

-

FOG-MAC012

Introduction to Medicine



-

1

Term Mark (5)

1

-

FOG-MAC071

Dental Prevention in Children

Department of Orthodontics and Pediatric Dentistry

Dr. Emil Segatto

1

-

Evaluation (5)

1

-


Credit

Course Requirement (SR=Subject requirement; ER=Examination requirement)

Smoking prevention in Dental practice

Department of Oral Surgery

Prof. Katalin Nagy

1

-

Evaluation (5)

1

-

Responses of the Living Cell to the enviroment


Prof. Dr. Kornél Kovács

2

-

Evaluation (5)

2

-

Faculty of Arts, Department of Communication and Media Studies


2

-

Evaluation (5)

2

-

Faculty of Arts, Hungarian Studies Program

Dr. Bertalan Pusztai

2

-

Evaluation (5)

2

-

Prof. György Szınyi

2

-

Evaluation (5)

2

-


2

-

Evaluation (5)

2

-

University of Szeged


2

-

Examination

2

-


SZTE

-

2

Term Mark (5)

2

-

Course Code

Course



Form of exam

159

Elective Subjects FOG-MAC041 FOG-MAE211

FOG-MAE041

Reflecting on a locality: Communication, Culture and Social Change in Szeged

FOG-MAE151 Hungarian Cultural History: the Visual Arts in an European Context FOG-MAE161 FOG-MAE171

Hungarian History 1000-1848

XA0021

Hungarian Literature General Elective Subjects

XN0211

SZTE Language Courses

Faculty of Arts, Hungarian Studies Program Faculty of Arts, Hungarian Studies Program

*One has to complete 2 semesters Physical Education until the end of the 1st year

Course Requirement (SR=Subject requirement; ER=Examinati on requirement)

FOG-MA013




2

-

Examination

2

ER: Anatomy I. lec.

FOG-MA014




-

3

Term Mark (5)

3

SR: Anatomy I. prac.

FOG-MA113




2

-

Examination

2

ER: Biology 1 lec.

FOG-MA114



1

-

Evaluation (5)

FOG-MA083



2

-

Examination

FOG-MA084



1

-

Evaluation (5)

FOG-MA103



Prof. Gábor Tóth

2

-

Examination

FOG-MA104



Prof. Gábor Tóth

-

Total 30

Term Mark (5)

FOG-MA051

Dental Instruments

Depatrment of Oral Surgery

Prof. Katalin Nagy

1

-

Evaluation (5)

1 -

FOG-MA052

Dental Instruments


Prof. Katalin Nagy

-

1

Term Mark (5)

1 -

Signature

0 -

Term Mark (5)

Course Code

Course



Credit

Form of exam

160

DENTISTRY BASIC MODULE (semesters 1-4) 2014/2015 1st year spring, 2nd semester Compulsory Subjects

Department of Oral Biology and Experimental Dental Research Department of Oral Biology and Experimental Dental Research Department of Oral Biology and Experimental Dental Research

ER: Biology 1 sem. ER: Physics 1 2 lec. ER: Physics 1 1 sem. 1

2

ER: Chemistry I. lec.

2 -


Nursing Practice


Prof. Katalin Nagy

-

FOG-MA232



Dr. Éva Demeter

-

2x35 hours 4

XT0011-PHE

Physical Education*

Sport Center


-

2

Signature

0 -



1

-

Evaluation (5)

1 -

0

SR: Hungarian I.

Compulsory Elective Subjects FOG-MAC021

Communication in Dentistry


FOG-MAC022

Communication in Dentistry

FOG-MAC091

Introduction to Informatics


FOG-MAC092

Introduction to Informatics

FOG-MAC031

Introduction to Chemistry

FOG-MAC032

Introduction to Chemistry


FOG-MAC051

Social Policy for Dental Students

Department of Public Health

Faculty of Science and Informatics, Institute of Informatics Department of Medical Chemistry

Credit


Form of exam

Course


Course Code

161 Course Requirement (SR=Subject requirement; ER=Examinatio n requirement)


-

1

Term Mark (5)

1 -

Dr. Richárd Farkas

1

-

Evaluation (5)

1 -

Dr. Richárd Farkas

-

2

Term Mark (5)

2 -

Prof. Gábor Tóth

1

-

Evaluation (5)

1 -

Prof. Gábor Tóth

-

1

Term Mark (5)

1 -

Dr. Edit Paulik

1

-

Evaluation (5)

1 -

Elective Subjects FOG-MAE091

Biochemical Basics of Preventive Medicine

Department of Biochemistry

Prof. László Dux

2

-

Evaluation (5)

2 -

FOG-MAE101

Molecular Developmental Biology


Prof. László Dux

2

-

Evaluation (5)

2 -


2

-

Evaluation (5)

2 -


2

-

Evaluation (5)

2 -

Department of Oral Biology and Experimental Dental Research Faculty of Arts, Department of Communication and Media Studies

FOG-MAE221

Selected Methods in Modern Biology

FOG-MAE051

Contemporary Culture and Media in Hungary

FOG-MAE181

Hungarian Films



2

-

Evaluation (5)

2 -

FOG-MAE191

History of Hungary 1848-2004



2

-

Evaluation (5)

2 -


2

-

Evaluation (5)

2 -

XA0021

Perspectives on Hungarian Culture General Elective Subjects

Faculty of Arts, Hungarian Studies Program University of Szeged

SZTE

2

-

Examination

2 -

XN0211

SZTE Language Courses


SZTE

-

2

Term Mark (5)

2 -

FOG-MAE201


162


Credit

Course

Form of exam

Course Code


SUGGESTED STUDY PLAN for 9002AK_N Study Plan Course Requirement (SR=Subject requirement; ER=Examinatio n requirement)

DENTISTRY BASIC MODULE (semesters 1-4) 2014/2015 2nd year fall, 3rd semester Compulsory Subjects FOG-MA015




2

-

Comp. Exam

2

FOG-MA016




-

2

Term Mark (5)

2

FOG-MA021

Dental Anatomy


Dr. Emil Segatto

2

-

Examination

2

FOG-MA022

Dental Anatomy


Dr. Emil Segatto

-

1

Term Mark (5)

1

FOG-MA031

Biochemistry


Prof. László Dux

2

-

Examination

2

FOG-MA032

Biochemistry


Prof. László Dux

-

1

Term Mark (5)

1

FOG-MA041

Physiology for Dental Students 1

Department of Medical Physiology

Prof. Gyula Sáry

4

-

Examination

3

FOG-MA042



2

Term Mark (5)

1

Dental Psychology


FOG-MA122

Dental Psychology


FOG-MA131

Ethics in Dentistry


FOG-MA132

Ethics in Dentistry


Prof. Gyula Sáry Dr. Katalin Barabás Dr. Katalin Barabás Dr. Katalin Barabás Dr. Katalin Barabás

-

FOG-MA121

FOG-MA161

Dental Materials and Technology

Department of Prosthodontics

FOG-MA162

Dental Materials and Technology

FOG-MA091

Dental Biometry and Evaluation of Research Results

FOG-MA092


1

Examination

SR: Anatomy II. lec,prac. SR: Anatomy II. lec,prac. SR: Anatomy II. lec,prac. SR: Anatomy II. lec,prac. SR: Chemistry 2 lec. Biology II. lec. SR: Chemistry 2 lec. Biology II. lec. ER: Physiology 1 prac. -

1

-

-

1

Term Mark (5)

1

-

1

-

Examination

1

ER: Dental Instruments lec. SR: Dental Instruments lec,prac.

-

1

Term Mark (5)

1

Dr. Zoltán Baráth

2

-

Examination

2


Dr. Zoltán Baráth

-

2

Term Mark (5)

2

Department of Oral Biology and Experimental Dental Research Department of Oral Biology and Experimental Dental Research


1

-

Evaluation (5)

1

-


-

1

Term Mark (5)

1

-


Dr. Éva Demeter

-

4

Term Mark (5)

0

ER: Hungarian 2



Curriculum 2014/2015 Form of exam

Credit

Course


Department of Medical Physiology Department of Orthodontics and Pediatric Dentistry Department of Oral Surgery

Prof. Gyula Sáry Dr. Emil Segatto Prof. Katalin Nagy

2 1 1

-

Evaluation (5) Evaluation (5) Evaluation (5)

2 1 1

-



Course Code

163

Compulsory Elective Subjects FOG-MAC101 FOG-MA071 FOG-MAC041

Physiology Seminar I. Dental Prevention in Children Smoking prevention in Dental practice




Prof. Mihály Boros

tota l 22

-

Evaluation (5)

3

-

FOG-MAE032



Prof. Mihály Boros

-

total 20

Signature

0

-

Reflecting on a locality: Communication, Culture and Social Change in Szeged Hungarian Cultural History: the Visual Arts in an European Context Hungarian History 1000-1848 Hungarian Literature General Elective Subjects SZTE Language Courses

Faculty of Arts, Department of Communication and Media Studies


2

-

Evaluation (5)

2

-



2

-

Evaluation (5)

-

Faculty of Arts, Hungarian Studies Program Faculty of Arts, Hungarian Studies Program University of Szeged University of Szeged

Prof. György Szınyi Prof. György Szınyi SZTE SZTE

2 2 2 -

2

Evaluation (5) Evaluation (5) Examination Term Mark (5)

-

FOG-MAE041 FOG-MAE151 FOG-MAE161 FOG-MAE171 XA0021 XN0211


2 2

164

DENTISTRY

Credit


Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

BASIC MODULE (semesters 1-4) Course Requirement (SR=Subject requirement; ER=Examination requirement)

2014/2015 2nd year spring, 4th semester Compulsory Subjects FOG-MA033

Biochemistry 2


Prof. László Dux

4

-

Comp. Exam

4

FOG-MA043



Prof. Gyula Sáry

4

-

Examination

4

FOG-MA044 FOG-MA141

Physiology for Dental Students 2 Medical Sociology

Prof. Gyula Sáry Dr. Edit Paulik

1

2 -

Term Mark (5) Examination

1 1

FOG-MA151

Oral Biology


2

-

Examination

2

FOG-MA152

Oral Biology

Department of Medical Physiology Department of Public Health Department of Oral Biology and Experimental Dental Research Department of Oral Biology and Experimental Dental Research


1

-

Evaluation (5)

1

FOG-MA171

Biomaterials and Biocompatibility in Dentistry



2

-

Evaluation (5)

2

FOG-MA181

Preclinical Course of Operative Dentistry 1

Department of Operative and Esthetic Dentistry

Dr. Antal Márk

1

-

Evaluation (5)

FOG-MA182

Preclinical Course of Operative Dentistry 1


Dr. Antal Márk

-

3

Term Mark (5)

FOG-MA191

Preclinical course of Prosthodontics 1


Dr. Zoltán Baráth

1

-

Evaluation (5)

FOG-MA192

Preclinical course of Prosthodontics 1


Dr. Zoltán Baráth

-

2

Term Mark (5)

Department of Prosthodontics Department of Foreign Languages

Dr. Zoltán Baráth Dr. Éva Demeter

-

2x35 hours 4

Signature preliminary exam

Criteria Subjects FOG-MA211 FOG-MA234

Odontotechnological Practice Hungarian Language 4

SR: Biochemistry 1lec,prac. ER: Physiology 1 lec, prac. SR: Biology 2 lec, sem. SR: Biology 2 lec, sem. ER: Dental materials lec.

SR: Dental 1 materials lec, prac. SR: Dental 3 materials lec, prac. SR: Dental 1 materials lec, prac. SR: Dental 2 materials lec, prac. 0 0 ER: Hungarian 3

Compulsory Elective Subjects FOG-MAC081 FOG-MAC102 FOG-MAC111 FOG-MAC051

Medical Anthropology Medical Physiology Seminar 2 Biochemistry Seminar Social Policy for Dental Students

Dept.of Behavioural Sciences Department of Medical Physiology Department of Biochemistry Department of Public Health

Dr. Katalin Barabás Prof. Gyula Sáry Prof. László Dux Dr. Edit Paulik

1 4 2 1

-

Qualification (5) Evaluation (5) Evaluation (5) Evaluation (5)

FOG-MAC042

Smoking prevention in Dental practice


Prof. Katalin Nagy

-

1

Term Mark (5)

1 4 2 1

SR: Smoking 1 prevention lec.


Dr. Antal Márk

Credit


Form of exam

Preclinical Course of Operative Dentistry Seminar


Hrs/week: Practice

FOG-MAC181

Course

Hrs/week: Theory

Course Code

165 Course Requirement (SR=Subject requirement; ER=Examination requirement)

1

-

Evaluation (5)

1

-




Prof. Mihály Boros

total 22

-

Evaluation (5)

3

-

FOG-MAE032



Prof. Mihály Boros

-

total 20

Signature

0

-

FOG-MAE111

Body development and diseases – a molecular biological background


Prof. László Dux

2

-

Evaluation (5)

2

-

FOG-MAE051

Contemporary Culture and Media in Hungary


2

-

Evaluation (5)

2

-

FOG-MAE181 FOG-MAE191 FOG-MAE201 XA0021 XN0211

Hungarian Films History of Hungary 1848-2004 Perspectives on Hungarian Culture General Elective Subjects SZTE Language Courses

Prof. György Szınyi Prof. György Szınyi Prof. György Szınyi SZTE SZTE

2 2 2 2 -

2

Evaluation (5) Evaluation (5) Evaluation (5) Examination Term Mark (5)

2 2

-

Faculty of Arts, Department of Communication and Media Studies Faculty of Arts, Hungarian Studies Program Faculty of Arts, Hungarian Studies Program Faculty of Arts, Hungarian Studies Program University of Szeged University of Szeged


166

DENTISTRY


Credit

Course

Form of exam

Course Code


Pre-Clinical Module

2014/2015 3rd year fall, 5th semester Compulsory Subjects FOG-KA211

General and Dental Radiology


Prof. Katalin Nagy

2

-

Examination

FOG-KA212

General and Dental Radiology


Prof. Katalin Nagy

-

2

Signature

3 0

FOG-KA221

Pharmacology I.

Department of Pharmacology


2

-

Evaluation (5)

2

FOG-KA222

Pharmacology I.



-

1

Signature

0

FOG-KA231

Pathophysiology I.

Department of Pathophysiology

Prof. Gyula Szabó

2

-

Examination

3

FOG-KA232

Pathophysiology I.


Prof. Gyula Szabó

-

2

Signature

0

FOG-KA241

Pathology and Oral Pathology I.

Department of Pathology

Prof. Béla Iványi

3

-

Examination

3

FOG-KA242

Pathology and Oral Pathology I.


Prof. Béla Iványi

-

2

Signature

0

FOG-KA251

Microbiology and Immunology I.

Department of Medical Microbiology and Immunobiology

Prof. Béla Prágai

3

-

Examination

3

FOG-KA252

Microbiology and Immunology I.


Prof. Béla Prágai

-

1

Signature

0

FOG-KA261

Preclinical course of Prosthodontics I.


Dr. Zoltán Baráth

1

-

Evaluation (5)

1

FOG-KA262

Preclinical course of Prosthodontics I.


Dr. Zoltán Baráth

-

2

Term Mark (5)

1

FOG-KA271

Preclinical Course of Operative Dentistry I.


Dr. Antal Márk

1

-

Evaluation (5)

2

FOG-KA272

Preclinical Course of Operative Dentistry I.


Dr. Antal Márk

-

4

Term Mark (5)

1

FOG-KA291

Gnatology


Dr. Zoltán Baráth

1

-

Evaluation (5)

1

FOG-KA292

Gnatology


Dr. Zoltán Baráth

-

3

Term Mark (5)

3

FOG-KA301

Introduction to Internal Medicine

1st Dept. of Internal Medicine

Prof. György Ábrahám

1

-

Evaluation (5)

1

FOG-KA311

Introduction to Surgery

Department of Surgery

Prof. György Lázár

1

-

Evaluation (5)

1

FOG-KA321

Public Health I.


Dr. Edit Paulik

1

-

Evaluation (5)

1



Credit


Form of exam

Course


Course Code

167 Course Requirement (SR=Subject requirement; ER=Examination requirement)

total 4total 4 3

Signature Signature Term Mark (5)

0 0 0

ER: Hungarian IV.

Criteria Subjects FOG-KA341 FOG-KA342-Dent 1 FOG-KA165

Dentist - Patient Communication Dentist - Patient Communication Hungarian Language V.

Department of Oral Surgery Department of Oral Surgery Department of Foreign Languages

Prof. Katalin Nagy Prof. Katalin Nagy Dr. Éva Demeter


Prof. Miháy Boros

total 12

Compulsory Elective Subjects FOG-KAC601

Introduction to Surgical Techniques

FOG-KAC602

Introduction to Surgical Techniques


Prof. Mihály Boros

FOG-KAC101

Bio- and Alloplastic Materials in Dentistry



-

Examination

2

-

total 14

Signature

0

-

2

-

Examination

2

1 total 22

-

Evaluation (5)

1

-

-

Evaluation (5)

3

-

total 20 2

Signature

0

-

Examination Term Mark (5)

2 2

-

Elective Subjects FOG-KAE131

Preclinical Course of Operative Dentistry Seminar I.


Dr. Antal Márk

FOG-KAE031



Prof. Mihály Boros

FOG-KAE0311



Prof. Mihály Boros

XA0021 XN0211

General Elective Subjects SZTE Language Courses

University of Szeged University of Szeged

SZTE SZTE

2 -

168

DENTISTRY


Credit

Course

Form of exam

Course Code


Pre-Clinical Module Course Requirement (SR=Subject requirement; ER=Examinatio n requirement)

2014/2015 3rd year spring, 6th semester Compulsory Subjects FOG-KA201 FOG-KA202

Advanced Imaging Techniques in Dentistry Advanced Imaging Techniques in Dentistry

Department of Oral Surgery Department of Oral Surgery

Prof. Katalin Nagy Prof. Katalin Nagy

1 -

1

Evaluation (5) Signature

1 0

FOG-KA223

Pharmacology II.



2

-

Examination

2

FOG-KA224

Pharmacology II.



-

1

Signature

0

FOG-KA233

Pathophysiology II.


Prof. Gyula Szabó

3

-

Examination

3

FOG-KA234

Pathophysiology II.


Prof. Gyula Szabó

-

2

Signature

0

FOG-KA243

Pathology and Oral Pathology II.


Prof. Béla Iványi

2

-

Examination

3

ER: Path.and Oral Path I. lect.

FOG-KA244

Pathology and Oral Pathology II.


Prof. Béla Iványi

-

2

Signature

0

-

FOG-KA263

Preclinical Course of Prosthodontics II.


Dr. Zoltán Baráth

1

-

Evaluation (5)

1

ER: Prec.C. of Prosth.I. lect.

FOG-KA264

Preclinical Course of Prosthodontics II.


Dr. Zoltán Baráth

-

4

Term Mark (5)

3

FOG-KA273

Preclinical Course of Operative Dent. II.


Dr. Antal Márk

1

-

Evaluation (5)

2

FOG-KA274

Preclinical Course of Operative Dent. II.


Dr. Antal Márk

-

4

Term Mark (5)

1


Dr. Antal Márk

-

-



2 -

1

preliminary exam Examination Signature

FOG-KA281 FOG-KA282

Preclinical Course of Operative Dent. preliminary exam Preclinical Course of Oral Surgery Preclinical Course of Oral Surgery

FOG-KA322

Public Health II.


Dr. Edit Paulik

1

-

Examination

2

FOG-KA323

Public Health II.


Dr. Edit Paulik

-

1

Signature

0

FOG-KA342-Dent Dentist - Patient Communication 2 FOG-KA331 Oral Surgery Summer Practice



total 4 total 140

Signature Signature

0 0

FOG-KA351

Preclinical Course of Prosthodontics and Gnatology


Dr. Zoltán Baráth

-

-

Comp. Exam

0

FOG-KA166

Hungarian Language VI.


Dr. Éva Demeter

-

3

Term Mark (5)

0

FOG-KA361

0 2 0

ER: Pharmacology I. ER: Pathophys. I. lect. -

SR: Prec.C. of Prosth.I. lect., pr. ER: Prec.C.of Op.Dent.I. lect. SR: Prec.C.of Op.Dent.I. lect., pr. Prec.C.of ER: Op.Dent.II. lect., -pr. ER: Public Health I. lect. -

Criteria Subjects ER: Prec.C. of Prosth.I. lect., pr., Gnatology ER: Hungarian IV.

Curriculum 2014/2015 Course Requirement (SR=Subject requirement; ER=Examinati on requirement)

Credit


Form of exam

Course


Course Code

169


Antimicrobial Chemotherapy


Dr. Katalin Burján

2

-

Evaluation (5)

2

-


Advanced Surgical Skills


Prof. Mihály Boros

total 12

-

Evaluation (5)

2

-

FOG-KAE038

Advanced Surgical Skills


Prof. Mihály Boros

-

total 12

Signature

0

-

FOG-KAE031



Prof. Mihály Boros

total 22

-

Evaluation (5)

3

-

FOG-KAE0311



Prof. Mihály Boros

Signature

0

-

FOG-KAE036 FOG-KAE051 FOG-KAE052 FOG-KAE132 XA0021 XN0211

Basic Immunpathology Dental Biometry and Evaluation of Research Results Dental Biometry and Evaluation of Research Results Preclinical Course of Operative Dentistry Seminar II. General Elective Subjects SZTE Language Courses

Institute of Surgical Research Department of Oral Biology and Experimental Dental Research of Oral Biology and Experimental Dental Department Research of Operative and Esthetic Dentistry Department University of Szeged University of Szeged

Prof. Mihály Boros Prof. János Minárovits Prof. János Minárovits Dr. Antal Márk SZTE SZTE

Evaluation (5) Evaluation (5) Signature Evaluation (5) Examination Term Mark (5)

1 2 0 1 2 2

-

1 1 1 2 -

total 20 1 2

170

DENTISTRY


Credit

Course

Form of exam

Course Code


CLINICAL MODULE (semester 7-10) (General Clinical Module: 30 credits, Dental Clinical Module: 95 credits) Course Requirement (SR=Subject requirement; ER=Examinatio n requirement)

2014/2015 4th year fall, 7th semester Compulsory Subjects in the General Clinical Module FOG-KA401 FOG-KA402 FOG-KA411

Internal Medicine I. Internal Medicine I. Dermatology

1st Dept. of Internal Medicine 1st Dept. of Internal Medicine Department of Dermatology

Prof. György Ábrahám Prof. György Ábrahám Prof. Lajos Kemény

3 1

FOG-KA412

Dermatology

Department of Dermatology

Prof. Lajos Kemény

-

FOG-KA421 FOG-KA422

Neurology Neurology

Department of Neurology Department of Neurology

Prof. László Vécsei Prof. László Vécsei

1 -

Department of Operative and Esthetic Dentistry Department of Operative and Esthetic Dentistry Department of Operative and Esthetic Dentistry Department of Prosthodontics Department of Prosthodontics Department of Oral Surgery Department of Oral Surgery Department of Oral Surgery Department of Periodontology Department of Periodontology Department of Periodontology Department of Periodontology

Dr. Antal Márk Dr. Antal Márk Dr. Antal Márk Dr. Zoltán Baráth Dr. Zoltán Baráth Prof. Katalin Nagy Prof. Katalin Nagy Prof. Katalin Nagy Dr. Laczkóné Dr. Turzó Kinga Dr. Laczkóné Dr. Turzó Kinga Dr. Laczkóné Dr. Turzó Kinga Dr. Laczkóné Dr. Turzó Kinga

1 1 1 2 1 1


Dr. Éva Demeter

2 total 3 1

Examination Signature Examination

4 0 1 -

Signature

0 -

Examination Signature

2 0 -

Compulsory Subjects in the Dental Clinical Module FOG-KA641 FOG-KA642 FOG-KA701 FOG-KA611 FOG-KA612 FOG-KA681 FOG-KA651 FOG-KA652 FOG-KA661 FOG-KA662 FOG-KA671 FOG-KA672

Operative Dentistry I. Operative Dentistry I. Endodontics Prosthodontics I. Prosthodontics I. Oral Surgery I. Oral Medicine I. Oral Medicine I. Infection Control in Dentistry Infection Control in Dentistry Periodontology I. Periodontology I.

6 7 3 1 1 2

Evaluation (5) Term Mark (5) Examination Evaluation (5) Term Mark (5) Term Mark (5) Examination Signature Examination Signature Examination Term Mark (5)

2 2 2 1 4 1 3 0 2 0 1 2

-

-

3

Term Mark (5)

0

SR: Hungarian VI.

Criteria Subjects FOG-KA167

Hungarian Language VII.


Esthetic Dentistry I.


Dr. Antal Márk

1

-

Examination

FOG-KAC541

Surgical Considerations in Dentistry

Department of Maxillofacial Surgery

Prof. Piffkó József

-

2

Term Mark (5)

1 SR: preclin c. of 2 Oral Surgery


FOG-KAC611

Microsurgery in Dentistry


Prof. Mihály Boros

total 10

FOG-KAC612

Microsurgery in Dentistry


Prof. Mihály Boros

-

FOG-KAC571

Scientific Circle


Prof. Zoltán Rakonczay

2

-

Credit


Form of exam

Course


Course Code

171 Course Requirement (SR=Subject requirement; ER=Examinatio n requirement)

Evaluation (5)

2 -

total 18 -

Signature

0 -

Evaluation (5)

2 -

-

Evaluation (5)

3 -




Prof. Mihály Boros

FOG-KAE0311



Prof. Mihály Boros

FOG-KAE113

Echocardiography Modern Diagnostic and Therapeutic Approach of Hemathology Operative Dentistry Seminar I. Esthetics of the Face Global Perspectives of Modern Management of Acute Bleeding in Obstetrics

2nd Dept. of Internal Medicine

Prof. Tamás Forster

FOG-KAE111 FOG-KAE141 FOG-KAE161 FOG-KAE061

total 22

2

total 20 -

Signature

0 -

Qualification (3)

2 -

2nd Dept. of Internal Medicine

Prof. Tamás Forster

2

-

Qualification (3)

2 -

Department of Operative and Esthetic Dentistry Department of Operative and Esthetic Dentistry

Dr. Antal Márk Dr. Antal Márk

1 1

-

Evaluation (5) Examination

1 1 -


Prof. Attila Pál

1

-

Qualification (3)

1 -

FOG-KAE062

Sexual Disorders - Gynecological Aspects


Prof. Attila Pál

1

-

Qualification (3)

1 -

FOG-KAE063 FOG-KAE064 FOG-KAE181 XA0021 XN0211

Modern Approach of the Gynecological Laparoscopy Actual Problems in Obstetric Immunology Demonstrator Activity General Elective Subjects SZTE Language Courses

Dept. of Obstetrics and Gynecology Dept. of Obstetrics and Gynecology Faculty of Dentistry University of Szeged University of Szeged

Prof. Attila Pál Prof. Attila Pál Prof. Zoltán Rakonczay SZTE SZTE

1 1 2 2 -

2

Qualification (3) Qualification (3) Evaluation (5) Examination Term Mark (5)

1 1 2 2 2

-

172

DENTISTRY

Credit

Course


1st Dept. of Internal Medicine 1st Dept. of Internal Medicine Department of Surgery Department of Surgery Dept. of Obstetrics and Gynecology Department of Psychiatry Department of Psychiatry Department of Anesthesiology and Intensive Therapy Department of Anesthesiology and Intensive Therapy

Prof. György Ábrahám Prof. György Ábrahám Prof. György Lázár Prof. György Lázár Prof. Attila Pál Prof. János Kálmán Prof. János Kálmán Prof. Zsolt Molnár Prof. Zsolt Molnár

2 2 1 1 1 -

1 1 1 1

Examination Signature Examination Signature Evaluation (5) Evaluation (5) Signature Examination Term Mark (5)

3 0 3 0 1 1 0 1 1

ER: Int. Med I. -lec. -

Department of Prosthodontics Department of Prosthodontics Department of Operative and Esthetic Dentistry Department of Operative and Esthetic Dentistry Department of Operative and Esthetic Dentistry Department of Prosthodontics Department of Prosthodontics Department of Prosthodontics Department of Oral Surgery Department of Oral Surgery Department of Oral Surgery Department of Oral Surgery Department of Orthodontics and Pediatric Dentistry Department of Orthodontics and Pediatric Dentistry Department of Periodontology Department of Periodontology Department of Periodontology

Dr. Zoltán Baráth Dr. Zoltán Baráth Dr. Antal Márk Dr. Antal Márk Dr. Antal Márk Dr. Zoltán Baráth Dr. Zoltán Baráth Dr. Zoltán Baráth Prof. Katalin Nagy Prof. Katalin Nagy Prof. Katalin Nagy Prof. Katalin Nagy Dr. Emil Segatto Dr. Emil Segatto Dr. Laczkóné Dr. Turzó Kinga Dr. Laczkóné Dr. Turzó Kinga Dr. Laczkóné Dr. Turzó Kinga

1 1 1 1 1 1 -

1 5 7 3 2 2 2 -

Evaluation (5) Signature Evaluation (5) Term Mark(5) preliminary exam Evaluation (5) Term Mark (5) preliminary exam Term Mark (5) Evaluation (5) Signature preliminary exam Examination Term Mark (5) Evaluation (5) Term Mark (5) preliminary exam

2 0 2 2 0 1 4 0 2 3 0 0 1 1 1 2 0

ER: Op. Dent I. lect. Op. Dent I. SR: lect.,Op. pr.,Dent II. ER: lect.,Prosth. pr. ER: I. lect. Prosth. I. SR: lect.,Prosth. pr. ER: II. lect.,Oral. pr. Surg. I. SR:



Course Code

Form of exam

CLINICAL MODULE

2014/2015 4th year spring, 8th semester Compulsory Subjects in the General Clinical Module FOG-KA403 FOG-KA404 FOG-KA431 FOG-KA432 FOG-KA441 FOG-KA451 FOG-KA452 FOG-KA511 FOG-KA512

Internal Medicine II. Internal Medicine II. Surgery Surgery Obstetrics and Gynecology Psychiatry Psychiatry Emergency medicine and anesthesiology in dentistry Emergency medicine and anesthesiology in dentistry

Compulsory Subjects in the Dental Clinical Module FOG-KA601 FOG-KA602 FOG-KA643 FOG-KA644 FOG-KA645 FOG-KA613 FOG-KA614 FOG-KA615 FOG-KA682 FOG-KA653 FOG-KA654 FOG-KA655 FOG-KA631 FOG-KA632 FOG-KA673 FOG-KA674 FOG-KA675

Dental Diagnostics and Treatment Planning Dental Diagnostics and Treatment Planning Operative Dentistry II. Operative Dentistry II. Operative Dentistry preliminary exam Prosthodontics II Prosthodontics II. Prosthodontics preliminary exam Oral Surgery II. Oral Medicine II. Oral Medicine II. Oral Medicine preliminary exam Pediatric Dentistry I. Pediatric Dentistry I. Periodontology II. Periodontology II. Periodontology preliminary exam

ER: Oral. Med. I. lect. Oral. Med. I. SR: lect.,Oral. pr. Med. II. ER: ER: Perio. I. lect. SR: Perio. I. lect., pr. Perio. II. ER: lect., pr.


Credit


Form of exam

Course


Course Code

173


Criteria Subjects

FOG-KA731

Basic Treatment in Dental Medicine (Summer Practice)


Dr. Judit Kádár-Nagy

total 140

FOG-KA168

Hungarian Language VIII.


Dr. Éva Demeter

-

Signature

0

3

Comp. Exam

0

Department of Operative and Esthetic Dentistry Faculty of Dentistry

Dr. Antal Márk Prof. Zoltán Rakonczay

2

1 -

Term Mark (5) Evaluation (5)

1 2

SR: Esthetic -Dentistry I.


Prof. Katalin Nagy

2

-

Examination

3

-


1

-

Evaluation (5)

2

-

-

1

Signature

0

-

tota l 22

Evaluation (5) Signature

3 0

-

Qualification (3)

1

-

1

-

Compulsory Elective Subjects FOG-KAC142 FOG-KAC571 FOG-KAC151

Esthetic Dentistry II. Scientific Circle Dental Treatment of Elderly People and Patients with Special Needs

ER: Prosth II. pr, Op.Dent. pr, Perio. II pr, Oral Surg II. pr., Ped. Dent. I pr, Em.Med. in An lect, pr. SR: Hungarian VII.



FOG-KAE052


Department of Oral Biology and Experimental Dental Research Department of Oral Biology and Experimental Dental Research Institute of Surgical Research Institute of Surgical Research

Prof. Mihály Boros Prof. Mihály Boros


FOG-KAE031 FOG-KAE0311

Animal Experiments in Medicine Animal Experiments in Medicine

FOG-KAE065

The Investigation of Male and Female Infertility and the Importance of Andrological Aspects


Prof. Attila Pál

1

total 20 -

FOG-KAE066

The Use of Gynecological Endoscopy with Respect on Average and Special Applications


Prof. Attila Pál

1

-

Qualification (3)

FOG-KAE067

Gynecological Endocrinology, Infertility


Prof. Attila Pál

1

-

Qualification (3)

1

-

FOG-KAE142 FOG-KAE111 FOG-KAE112 FOG-KAE181 XA0021 XN0211

Operative Dentistry Seminar II. Modern Diagnostic and Therapeutic Approach of Hemathology Arythmology

Department of Operative and Esthetic Dentistry 2nd Dept. of Internal Medicine 2nd Dept. of Internal Medicine Faculty of Dentistry University of Szeged University of Szeged

Dr. Zoltán Baráth Prof. Tamás Forster Prof. Tamás Forster Prof. Zoltán Rakonczay SZTE SZTE

1 1 1 2 2 -

2

Evaluation (5) Qualification (3) Qualification (3) Evaluation (5) Examination Term Mark (5)

1 1 1 2 2 2

-

Demonstrator Activity General Elective Subjects SZTE Language Courses

174

DENTISTRY

Credit


FOG-KA461


Department of Otolaryngology and Head & Neck Surgery

Prof. László Rovó

2

-

Examination

3

-

FOG-KA462


Department of Otolaryngology and Head & Neck Surgery

Prof. László Rovó

-

1

Signature

0

-

FOG-KA481 FOG-KA482 FOG-KA471

Pediatrics Pediatrics Forensic Medicine

Department of Pediatrics Child Health Center Department of Pediatrics Child Health Center Department of Forensic Medicine

Dr. Csaba Bereczki Dr. Csaba Bereczki Dr. Éva Kereszty

2 1

total 7 -

Examination Signature Examination

2 0 1

-

SR: Prosthodontics preliminary exam

Course Code

Course



Form of exam

CLINICAL MODULE

2014/2015 5th year fall, 9th semester Compulsory Subjects in the General Clinical Module

Compulsory Subjects in the Dental Clinical Module FOG-KA616

Prosthodontics III.


Dr. Zoltán Baráth

-

6

Term Mark (5)

3

FOG-KA646

Operative Dentistry III.


Dr. Antal Márk

-

4

Term Mark (5)

2

FOG-KA683

Oral Surgery III.


Prof. Katalin Nagy

2

-

Evaluation (5)

1

FOG-KA684

Oral Surgery III.


Prof. Katalin Nagy

4

Term Mark (5)

3

FOG-KA633

Pediatric Dentistry II.


Dr. Emil Segatto

1

-

Evaluation (5)

2

FOG-KA616

Prosthodontics III.


Dr. Anette Stájer

-

6

Term Mark (5)

3

FOG-KA646

Operative Dentistry III.


Dr. Zoltán Baráth

-

4

Term Mark (5)

2

FOG-KA683

Oral Surgery III.


Prof. Katalin Nagy

2

-

Evaluation (5)

1

FOG-KA684

Oral Surgery III.


Prof. Katalin Nagy

4

Term Mark (5)

3

FOG-KA634 FOG-KA621 FOG-KA622

Pediatric Dentistry II. Orthodontics I. Orthodontics I.

Department of Orthodontics and Pediatric Dentistry Department of Orthodontics and Pediatric Dentistry Department of Orthodontics and Pediatric Dentistry

Dr. Emil Segatto Dr. Emil Segatto Dr. Emil Segatto

4 2

Term Mark (5) Examination Term Mark (5)

2 2 1

1 -

SR:Op. Dentistry preliminary exam SR: Oral Surgery II. pr. SR: Oral Surgery II. pr. ER: Pediatric Dentistry I. SR: Prosthodontics preliminary exam SR:Op. Dentistry preliminary exam SR: Oral Surgery II. pr. SR: Oral Surgery II. pr. -


Credit


Form of exam

Course


Course Code

175 Course Requirement (SR=Subject requirement; ER=Examination requirement) SR: Periodontology SR: Periodontology preliminary exam -

FOG-KA676

Periodontology III.

Department of Periodontology

Dr. Laczkóné Dr. Turzó Kinga

1

-

Evaluation (5)

1

FOG-KA677

Periodontology III.



-

3

Term Mark (5)

2

FOG-KA691

Practice Management in Dentistry


Dr. Emil Segatto

2

-

Examination

2

FOG-KA711

Dental Implantology I.


Prof. Katalin Nagy

2

-

Evaluation (5)

2

SR: Oral Surgery II. pr.

FOG-KA721

Preventive Dentistry


Prof. Katalin Nagy

1

Examination

1

-

FOG-KA722

Preventive Dentistry


Prof. Katalin Nagy

-

1

Term Mark (5)

1

FOG-KA676

Periodontology III.



1

-

Evaluation (5)

1

FOG-KA677

Periodontology III.



-

3

Term Mark (5)

2

SR: Periodontology preliminary exam SR: Periodontology preliminary exam


Prof. Katalin Nagy

2

-

Qualification (3)

2


2

-

Examination

2

Dental and Medical Departments

2

Signature

0

-


Weekly Scientific Session I.

-

Elective Subjects XA0021

General Elective Subjects

Criteria Subject FOG-ASZD101

Thesis Consultation

Compulsory Elective Subjects FOG-KAC161 FOG-KAC141 FOG-KAC571

Weekly Scientific Session I. Esthetic Dentistry I. Scientific Circle

Faculty of Dentistry Department of Operative and Esthetic Dentistry Faculty of Dentistry

Prof. Zoltán Rakonczay Dr. Antal Márk Prof. Zoltán Rakonczay

2 1 2

-

Qualification (3) Examination Evaluation (5)

2 1 2

-

Department of Prosthodontics and Oral Biology Department of Prosthodontics and Oral Biology Department of Operative and Esthetic Dentistry Department of Operative and Esthetic Dentistry Department of Prosthodontics Institute of Surgical Research Institute of Surgical Research Faculty of Dentistry

Dr. Zoltán Baráth Dr. Zoltán Baráth Dr. Antal Márk Dr. Antal Márk Dr. Zoltán Baráth Prof. Mihály Boros Prof. Mihály Boros Prof. Zoltán Rakonczay

1 1 1 1 1 tota l 22

total 20 -

Evaluation (5) Signature Examination Evaluation (5) Term Mark (5) Evaluation (5) Signature Evaluation (5)

2 0 1 1 1 3 0 2

SR: Prosthodontics II. SR: -Prosthodontics II.

Elective Subjects FOG-KAE055 FOG-KAE056 FOG-KAE161 FOG-KAE143 FOG-KAE151 FOG-KAE031 FOG-KAE0311 FOG-KAE181

Diseases of the Temporomandibular System Diseases of the Temporomandibular System Esthetics of the Face Operative Dentistry Seminar III. Prosthodontics seminar I. Animal Experiments in Medicine Animal Experiments in Medicine Demonstrator Activity

2

SR: Operative Dentistry SR: -Prosthodontics -

176

DENTISTRY


Credit

Course

Form of exam

Course Code


CLINICAL MODULE


2014/2015 5th year spring, 10th semester Compulsory Subjects in the General Clinical Module FOG-KA501 FOG-KA491 FOG-KA492

Medical Genetics Ophthalmology Ophthalmology

Department of Medical Genetics Department of Ophthalmology Department of Ophthalmology

Prof. Dr. Márta Széll Prof. Dr. Andrea Facskó. Prof. Dr. Andrea Facskó

1 1 -

total 3

Evaluation (5) Examination Signature

1 1 0 3 SR: Prosthodontics SR: Operative 3 Dentistry III. pr. SR: Oral 4 Srugery III. lect, pr. ER: Pediatric 2 Dentistry II. lect.

Compulsory Subjects in the Dental Clinical Module FOG-KA617

Prosthodontics IV.


Dr. Anette Stájer

-

6

Term Mark (5)

FOG-KA647

Operative Dentistry IV.


Dr. Zoltán Baráth

-

6

Term Mark (5)

FOG-KA685

Oral Surgery IV.


Prof. Katalin Nagy

-

6

Term Mark (5)

FOG-KA635

Pediatric Dentistry III.


Dr. Emil Segatto

-

3

Term Mark (5)

FOG-KA623

Orthodontics II.


Dr. Emil Segatto

1

-

Evaluation (5)

ER: 2 Orthodontics I. lect.

FOG-KA624

Orthodontics II.


Dr. Emil Segatto

-

2

Term Mark (5)

1 -

FOG-KA678

Periodontology IV.



1

-

Signature

FOG-KA679

Periodontology IV.



-

3

Term Mark (5)

FOG-KA712

Dental Implantology II.


Prof. Katalin Nagy

-

2

Term Mark (5)

ER: 0 Periodontology III. lect. SR: 2 Periodontology III. lect., pr. ER: Dental 2 Implantology I. lect.

Criteria Subjects FOG-KA617

Prosthodontics IV.


Dr. Zoltán Baráth

-

6

Term Mark (5)

SR: 3 Prosthodontics III. pr.

FOG-KA647

Operative Dentistry IV.


Dr. Márk Antal

-

6

Term Mark (5)

3

SR: Operative Dentistry III. pr.


Credit


FOG-KA761

Pediatric Dentistry and Orthodontics


Dr. Emil Segatto

-

-

Comp. Exam

0

ER: Orthodontics II. lect, Pediatric Dent. III. pr.

FOG-KA685

Oral Surgery IV.


Prof. Katalin Nagy

-

6

Term Mark (5)

4

SR: Oral Srugery III. lect, pr.

FOG-KA781

Periodontology



-

-

Comp. Exam

0

-

Course Code

Course



Form of exam

177


Weekly Scientific Session II.


Prof. Zoltán Rakonczay

2

-

Qualification (3)

2

ER: Weekly Scientific Session I. lect.

FOG-KAC142

Esthetic Dentistry II.


Dr. Márk Antal

-

1

Term Mark (5)

1

SR: Esthetic Dentistry I. Lect.

FOG-KAC171

Dental Implantology in Prosthodontics


Dr. Zoltán Baráth

2

-

Evaluation (5)

2

ER: Dent. Impl. I. lect.

FOG-KAC561

Child and Adolescent Psychiatry, Mentalhygiene

Department of Child and Adolescent Psychiatry

Dr. Ágnes Vetró

2

-

Examination

2

FOG-KAC621

Digital Restaurative Dentistry


Dr. Zoltán Baráth

1

-

Evaluation (5)

1

Dr. Emil Segatto

2

-

Evaluation (5)

3

Dr. Emil Segatto

-

1

Signature

0

SR: preclin. mod.

Elective Subject Treatment of Traumatic Dental Injuries in Childhood Lecture Treatment of Traumatic Dental Injuries in Childhood Seminar

Department of Orthodontics and Pediatric Dentistry Department of Orthodontics and Pediatric Dentistry

FOG-KAE144

Operative Dentistry Seminar IV.


Dr. Márk Antal

1

-

Evaluation (5)

1

FOG-KAE152

Prosthodontics seminar II.


Dr. Zoltán Baráth

1

-

Term Mark (5)

1

FOG-KAE031



Prof. Mihály Boros

total 22

-

Evaluation (5)

3

Prosthodontics preliminary exam -

FOG-KAE0311



Prof. Mihály Boros

Signature

0

-

XA0021 XN0211

General Elective Subjects SZTE Language Courses

University of Szeged University of Szeged

SZTE SZTE

Examination Term Mark(5)

2 2

-

FOG-KAE053 FOG-KAE054

2 -

total 20 2

SR: Pediatric Dent. II. lect. SR: Pediatric Dent. II. pr. SR: Operative Dentistry preliminary SR:

178 FOG-KAE031



Prof. Mihály Boros

total 22

-

Evaluation (5)

3

-

Faculty of Dentistry Faculty of Dentistry Faculty of Dentistry Faculty of Dentistry

Prof. Katalin Nagy Prof. Katalin Nagy Prof. Katalin Nagy Prof. Katalin Nagy

-

-

State Board Examination

20 0 0 0

Thesis Thesis Thesis

State Board Examination Thesis Written Test Patient Examination - Oral exam Patient Examination - Practical exam

178 Recommended textbooks for first year dental students For the textbooks of the medical basic module subjects check the medical recommended textbooks (pg: 56.) DENTAL ANATOMY • Nelson, Ash: Wheeler's Dental Anatomy, Physiology and Occlusion, 9th Edition, Saunders – 2010 • Scheid, Weiss: Woelfel's Dental Anatomy: Its Relevance to Dentistry, 8th Edition, Lippincott Williams & Wilkins – 2012 DENTAL INSTRUMENTS • Linda R. Boyd: Dental Instruments, A Pocket Guide, 3rd ed. 2008. COMMUNICATION IN DENTISTRY • Atkinson and Hilgard: Introduction to psychology. Andover, Wadsworth Cengage Learning, 2009.

Recommended textbooks for second year dental students ETHICS IN MEDICINE • Ronald Munson: Intervention and Reflection. Basic Issues in Medical Ethics (Wadsworth Publishing Company, 2004) • World Medical Association (WMA, http://www.wma.net/e/about/index.htm ) • WMA Ethics Manual (http://www.wma.net/e/ethicsunit/resources.htm ) • WMA Policy (http://www.wma.net/e/policy/b3.htm ) • The Declaration of Genecva (http://www.cirp.org/library/ethics/geneva/ ) • The Declaration of Helsinki (http://www.fda.gov/oc/health/helsinki89.html ) DENTAL MATERIALS AND TECHNOLOGY • Dental Materials and Their Selection: Edited by W.J. O’Brien. Quintessence Publishing Co, Inc. ORAL BIOLOGY • Oral Biology. By B.G. Jansen van Rensburg, 1995. Quintessence Publ. Co, Inc. ISBN 0-86715-271-0; • Oral bioscience. David B. Ferguson, 1999, Churchill Livingstone, ISBN 0-433 05373 1. MEDICAL PSYCHOLOGY • Humphris, G. & Ling, M. S. (2000): Behavioural Sciences for Dentistry. Antony Rowe Ltd, Eastbourne

Recommended textbooks for third year dental students For the textbooks of the medical pre-clinical module subjects check the medical recommended textbooks (pg: 58.) PHARMACOLOGY • Katzung: Basic and Clinical Pharmacology, McGraw-Hill Medical, 11th ed., 2008. • Rang & Dale’s Pharmacology, Churchill-Livingstone, 6th ed., 2007. HUNGARIAN LANGUAGE • Putz Mónika: Magyar fogorvosi szaknyelv, Semmelweis Egyetem, Bp.2006 • Györffy Mária: Mi a panasz? PTE, Pécs 2003 PRECLINICAL COURSE OF ORAL SURGERY • Dimitroulis, G: Synopsis of Minor Oral Surgery, Elsevier, 1996 • Szabó Gy: Oral and Maxillofacial Surgery, Alapítvány a Száj-, Arc, és Állcsontsebészeti Betegségek Gyógyításáért Bp., 1997 PRECLINICAL COURSE OF PROSTHODONTICS • Shillingburg HT, Jacobi R, Brackett SE: Fundamentals of Tooth Preparation. Quintessence, 2nd printing, ISBN 0-86715-157-9 • SF Rosenstiel, MF Land, J Fujimoto: Contemporary Fixed Prosthodontics, 2001, 3rd ed., ISBN 0-8151-5559-X


179

GENERAL AND DENTAL RADIOLOGY • Pasler, FA, Visser, H: Pocket of Dental Radiology. Stuttgart: Thieme, 2007 • White, SC, Pharoah, MJ: Oral Radiology Principles and Interpretation, 2009, Mosby, St. Louis BIO- AND ALLOPLASTIC MATERIALS IN DENTISTRY • B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemons: Biomaterials Science: An Introduction to Materials in Science. Academic Press, 1996 PRECLINICAL COURSE OF OPERATIVE DENTISTRY • Summit J.B. et al. Fundamentals of Operative Dentistry, Quintessence Publ. Inc. 2006. GNATOLOGY • Wheeler’s Dental Anatomy, Physiology and Occlusion • McNeill: Science and Practice of Occlusion, Quintessence 1997. • Klineberg_Jagger Occlusion and Clinical Practice, Wright 2004. • Thomas- Tatenoi: Die gnathologische Okklusion, Quintessenz 1982. • Stuart: Full Mouth Waxing Technique, Quintessence 1984. DENTIST-PATIENT COMMUNICATION • Margaret L Loyd – Robert Bor: Communication Skills for Medicine, Elsevier, Second edition 2004. ADVANCED IMAGING TECHNICS IN DENTISTRY • Pasler, FA, Visser, H: Pocket of Dental Radiology. Stuttgart: Thieme, 2007 • White, SC, Pharoah, MJ: Oral Radiology Principles and Interpretation, 2009, Mosby, St. Louis PATHOPHYSIOLOGY Texbooks • Gayton and Hall: Texbook of Medical Physiology 12th ed. 2011 ISBN: 978-1-4160-4574-8/978-0-8089-2400-5 • Damjanov: Pathophysiology, Elsevier (Saunders title), 2008, ISBN: 978-1-4160-0229-1 • McPhee, Hammer: Pathophysiology of Disease 6th ed., McGraw-Hill Medical, 2009, ISBN- 0071621679/9780071621670 • Silbernagl, Lang: Color Atlas of Pathophysiology, George Thieme Verlag, 2000, ISBN: 9780865778665/9783131165510 • Kumar, Abbas, Fausto, Aster: Robbins & Cotran Pathologic Basis of Disease, 8th ed, Elsevier (Saunders title) 2010, ISBN: 978-1-4160-3121-5 • Goldman, Schafer: Goldman’s Cecil Medicine, 24th ed., Elsevier (Saunders title), 2012, ISBN: 978-1-4377-2788-3 • Longo, Fauci, Kasper, Hauser, Jameson, Loscalzo: Harrison’s Principles of Internal Medicine, 18th ed., McGraw-Hill Medical, 2012, ISBN 9780071748896/007174889X Handouts (for practice) • Fekete M.: Pathophysiology exercises II. 1987. • Szabó G.: Introduction to Electrocardiography 1999. PUBLIC HEALTH • Paulik E (ed.): Public Health and Preventive Medicine. Medicina Publishing House, Budapest, 2013

180 • Recommended textbooks for fourth and fifth year dental students OPERATIVE DENTISTRY • Summitt J. B. et al. Fundamentals of Operative Dentistry, Quintessence Publishing Inc., 2006 • Beer R. et al. Pocket Atlas of Endodontics. Thieme 2006 ESTHETIC DENTISTRY • Domenico Massironi, Romeo Pascetta, and Giuseppe Romeo: Percision in Dental Esthetics. Clinical and Laboratory Procedures. 464 pp., 2005. ENDODONTICS • Beer R, Baumann MA, Kim S: Endodontology in: Series of Color Atlas of Dental Medicine. Thieme Stuttgart, New York 2000. PROSTHODONTICS • Zarb, GA, Bolender, ChL (Ed.) Prosthodontic Traetment for Edentulous Patients. Complete Dentures and Implant-Supported Prostheses. 12th ed. Mosby, 2004. • Graber G: Removable partial Dentures, Thieme (ed: Rateitschak K. H.), 1988. ORAL SURGERY • Dimitroulis, G: Synopsis of Minor Oral Surgery, Elsevier, 1996 • Szabó Gy: Oral and Maxillofacial Surgery, Alapítvány a Száj-, Arc, és Állcsontsebészeti Betegségek Gyógyításáért Bp., 1997 ORAL MEDICINE • Dr. István Sonkodi: Oral Medicine (1993, 1996). • Dr. István Sonkodi: Oral and Maxillofacial Medicine (2006). INFECTION CONTROL IN DENTISTRY • Infection Control in Dentistry. Basic Guide Lines Tempus Join Europian Project. • E. Dietz: Safety standards and Infection Control in Dental Assistants. Delma, Tompson Leasning, 2002. DENTAL DIAGNOSTICS AND TREATMENT PLANNING • Stefanac, SJ, Nesbit, SP: Treatment Planning in Dentistry 2nd ed. (with CD) Mosby Elsevier: St. Louis, 2007 • Content of the lectures • Relating parts of recommended dental books DENTAL BIOMETRY AND EVALUATION OF RESEARCH RESULTS • G. M. Clarke: Statistics and experimental design. A series of student texts in CONTEMPORARY BIOLOGY. Eds: A. J. Willis, M. A. Sleigh, by Edward Arnold (Publishers) Ltd, Second Edition, 1980 • J.A. von Fraunhofer and J.J. Murray: Statistics in Medical, Dental and Biological Studies,TRI-MED BOOKS LTD. First published 1976 PEDIATRIC DENTISTRY • Richard J. Mathewson; Robert E. Primosh: Fundamentals of pediatric dentistry-Quintessence • Koch, G, Poulsen, S. (Ed.) Pediatric Dentistry. A clinical approach. Copenhagen: Blackwell Munksgaard, 482 p., 25 cm, 2009. PERIODONTOLOGY • Lindhe J, Lang NP, Karring T: Clinical Periodontology and Implant Dentistry. Fifth Edition. 2008. ISBN: 9781405160995 • Wolf HE edited: Color Atlas of Dental Medicine: Periodontology. Georg Thieme Verlag. 2005. 3rd edition. ISBN: 9780865779020 / 9783136750032 • Newman MG, Takei HH, Klokkevold PR, Carranza FA: Carranza’s Clinical Periodontology Elsevier Saunders 2011. 11th ed., ISBN: 9781437704167 • Nield-Gehrig JS, Willmann DE.: Foundations of Periodontics for the Dental Hygienist. Lippincott Williams & Wilkins, 2011. 3rd ed. ISBN: 9781605475738 DENTAL IMPLANTOLOGY • Myron Nevins, James T. Mellonig: Implant Therapy

Curriculum 2014/2015 •

181

Hubertus Spiekermann: Implantology

DENTAL IMPLANTOLOGY (IN PROSTHODONTICS) • Myron Nevins, James T. Mellonig: Implant Therapy • Hubertus Spiekermann: Implantology • Misch CE: Dental Implant Prosthetics • Content of the lectures ORTHODONTICS • TEXTBOOK OF ORTHODONTICS by Samir Bishara, DDS, BDS, Dortho, MS, Professor, Department of Orthodontics, University of Iowa, College of Dentistry, Iowa City, IABibliographyic & ordering Information, Hardbound, 592 pages, publication date: MAR-2001, Imprint: SAUNDERS DISEASES OF TEMPOROMANDIBULAR SYSTEM • Bumann, A., Lotzmann, U. TMJ Disorders and Orofacial Pain. The Role of Dentistry in a Multidisciplinary Diagnostic Approach. Color Atlas of Dental Medicine, Stuttgart New York: Thieme, 2005 • Zarb, GA, Carlsson, GE, Sessle, BJ, Mohl, ND (Ed.): Temporomandibular Joint and Masticatory Muscle Disorders. 2nd ed. Munksgaard: Copenhagen, 1994 TREATMENT OF TRAUMATIC DENTAL INJURIES IN CHILDHOOD • J.O. Andreasen , F.M. Andreasen and L. Andersson: Essentials of Traumatic Injuries to the Teeth, Blackwell Munksgaard, 2011. DENTAL TREATMENT OF ELDERLY PEOPLE AND PATIENTS WITH SPECIAL NEEDS • Textbook of Geriatric Dentistry. Third Ed. Editors: P. Holm-Pedersen, A. Walls, J. Ship, Blackwell Munksgaard, 2007.06.26. FORENSIC MEDICINE • Payne-James, Jones, Krach, Manlove: Simpson's Forensic Medicine 13th Edition, 2011 Hodder & Stoughton Ltd. ISBN 978 0 340 986 035 •

Péter Sótonyi, Éva Keller (ed.) Lecture Notes of Forensic Medicine, Semmelweis Kiadó, Budapest 2008 ISBN: 9789639656925

ESTHETICS OF THE FACE • • •

Cohen, Michael: Interdisciplinary Treatment Planning, Volume II: Comprehensive Case Studies (ISBN 978-086715-501-3) John E.Griffin, King Kim: Cosmetic Surgery for the Oral and Maxillofacial Surgeon (ISBN: 978-0-86715-4900) Chu, Stephen J, Devigus, Alessandro and Mieleszko, Adam J.: Fundamentals of Color: Shade Matching and Communication in Esthetic Dentistry (ISBN: 0-86715-434-9)

HUNGARIAN LANGUAGE • Putz Mónika: Magyar fogorvosi szaknyelv, Semmelweis Egyetem, Bp.2006 • Györffy Mária: Mi a panasz? PTE, Pécs 2003 DERMATOLOGY • J. A. A. Hunter, J. A. Savin, M. V. Dahl: Clinical Dermatology, Blackwell Scientific Publications 2nd ed. ISBN:0632037148

182 SYLLABUSES BASIC MODULE - DENTISTRY For the syllabus of the general basic module subjects check the medical syllabus (pg.: 65). DENTAL INSTRUMENTS 1st semester

* * * * * * * *

LECTURE (1 hr/week) 1. Introduction to the Szeged Dental School 2. History of Dentistry (Stone age – Greco-Roman Dentistry) 3. History of Dentistry (Greco-Roman Dentistry – Western Dentistry) 4. History of Dentistry (Western Dentistry – today) 5. Fully equipped dental surgery 6. Visiting a private dental practice 7. Dental instruments used in oral surgery

PRACTICE (1 hr/week)

8. Dental Instruments used in operative dentistry, endodontics 9. X-ray machine, Orto-pan tomogram 10. Dental instruments used in prosthetic dentistry 11. Dental Instruments used in orthodontics and children dentistry and periodontology, oral hygiene instruments 12. Exam 13. Semester overview 14. Consultation

* * *

* *

DENTAL ANATOMY 1st semester

* *

* * * * * * * * *

LECTURE (2 hours/week) 1. The object and importance of Dental Anatomy. Biomimetics 2. Dental terminology and nomenclature. Orientation, surfaces. Shape elements, contact points, positions 3. Primary tooth anatomy 4. Structure of permanent teeth 5. Maxillary incisors 6. Mandibular incisors 7. Maxillary and mandibular canines 8. Maxillary premolars 9. Mandibular premolars 10. Maxillary molars 11. Mandibular molars

PRACTICE (1 hour/week) 1. Tooth structure - drawing exercise in 2D and 3D, study of pulpal sections 2. Maxillary incisors. Natural tooth identification. Drawing exercise 3. Mandibular incisors. Natural tooth identification. Drawing exercise 4. Maxillary and mandibular canines. Natural tooth identification. Drawing exercise 5. Maxillary premolars. Mandibular premolars. Natural tooth identification. Drawing exercise 6. Maxillary molars. Natural tooth identification. Drawing exercise 7. Mandibular molars. Natural tooth identification. Drawing exercise 8. Maxillary incisors. Tooth model reconstruction with plasticine 9. Mandibular incisors. Tooth model reconstruction with plasticine 10. Maxillary and mandibular canines. Tooth model reconstruction with plasticine 11. Maxillary premolars. Mandibular premolars. Tooth model reconstruction with plasticine


183

12. Variation in form and shape. Incisors and canines. Premolars 13. Variation in form and shape. Premolars and molars

12. Maxillary molars. reconstruction with plasticine 13. Mandibular molars. reconstruction with plasticine

Tooth

model

Tooth

model

CHEMISTRY FOR DENTAL STUDENTS 1st smester (14 weeks) WEEK 1.

2.

3.

4.

5.

LECTURE (2 hrs/week) Basic terms. The mole concept. Basic structure of atoms. Electronic structure of atoms. Atomic theories. The periodic table. Explanation of periodic properties. Chemical bonding. Octet rule. Ionic bonding. Ionic solids, monatomic and polyatomic ions. Covalent bonds. Characterization of molecules. Dipole moment. Molecular geometry. Metallic bonding. Intermolecular forces: hydrogen bonding and van der Waals forces (dipoledipole and London forces). Introduction to inorganic chemistry. Types of metathesis reactions. Classification and properties of metals. Alloys. Properties and compounds of alkali metals, alkaline-earth metals and aluminum. Properties and compounds of d-transition metals. Complex ions and chelates. Hydrogen and its compounds. Importance of radioactive isotopes in medicine. Properties of the most important nonmetals and their compounds. Biological importance and usage. Formation and physiological effects of free radicals.

SEMINAR PRACTICE (1 hr/week) (2 hrs/week – 8 weeks) Review of laboratory No practice these weeks. requirements. Fire and safety precautions. Requirements for completion of the semester.

Electronic configuration of atoms. Chemical calculations: concentration of solutions.

The periodic table. Continuation of practicing simple chemical calculations.

Intra- and intermolecular chemical bonds. Titration calculations.

Background of volumetric analysis. Using a pipette and a burette. The principle of photometry, Lambert-Beer law.

Metals and their compounds. Complexes. Metathesis reactions.

During weeks 5 to 9 students work in rotation and conduct one of the following experiments each week: I) Quantitative determination of HCl content by titration with

184 7.

8.

9.

10.

11.

12.

Osmosis and its biological importance. Chemical equilibrium. LeChatelier's principle. Electrolytic dissociation, strong and weak electrolytes. Acid-base concepts. Self-ionization of water, pH and pOH. Acid-base ionization equilibrium. Acid-base titration. Common-ion effect. Buffers and their biological importance. Electrochemistry. Redox reactions. Standard reduction potentials. Strength of oxidizing or reducing agents. Voltaic cells, types of electrodes. Reference electrodes. Glass electrodes, measurement of pH. Electrolysis. Reaction kinetics. Rate, order, molecularity and mechanism of reactions. Complex chemical reactions. Catalysis. Enzymes as biocatalysts. Thermochemistry. Basic terms. First, second and third laws of thermodynamics. Entropy and disorder. Change in Gibb's free energy and spontaneity of a reaction. General principles of organic chemistry. Classification of organic compounds. Functional groups. Types of organic chemical reactions: substitution, addition, and elimination. Alkanes (paraffin hydrocarbons). Cycloalkanes. Alkenes. Addition and polymerization. Dental polymers. Dental composites, their structure. Alkynes. Structure of conjugated dienes. Isoprene and terpenes. Carotinoids. Vitamin A. The photochemistry of vision.

Solutions. Continuation of practicing simple chemical calculations.

of Fe(II)-content by permanganometric titration measuring the redox potential. VII) Photometric determination of iron.

Chemical equilibrium. Application of LeChatelier’s principle. Acid-base concepts.

Simple pH calculations. Buffers, calculations involving buffers.

Oxidation-reduction reactions. Voltaic cells.


Brief summary of chemical thermodynamics and reaction kinetics.

Types of organic chemical reactions. Saturated hydrocarbons: alkanes and cycloalkanes.

No practice these weeks.


14.

Aromatic hydrocarbons. Structure and reactions of benzene. Organic halogen compounds. Hydroxyl group containing organic compounds: alcohols, enols and phenols. Classification, nomenclature and chemical properties of alcohols. Esters of alcohols formed with inorganic acids. Phenols. Acidity of phenols. Oxidation of phenols, quinones. Ethers. Thioalcohols, thioethers, sulfoxides and sulfones.

185 Unsaturated hydrocarbons: alkenes and alkynes. .

Aromatic hydrocarbons Organic halogen compounds.

2nd smester (14 weeks) WEEK LECTURE (2 hrs/week) 1. Three-dimensional structure of molecules: constitution, configuration and conformation. Optical isomerism. Enantiomers, racemates. Configuration: D-L and R-S systems. Molecules with more than one chiral centers. Diastereomers. 2.

3.

4.

5.

Classification and nomenclature of amines. Basicity of amines, salt formation. Biologically important amines and aminoalcohols. Amines as neurotransmitters. Reactions of amines. Sulfonamides. Classification and nomenclature of heterocyclic compounds. Three- and four-membered heterocycles: betalactams. Five-membered heterocycles with one and two heteroatoms. Six-membered heterocycles with one heteroatom: nicotinamide, flavonoids. Six-membered heterocycles with two heteroatoms: pyrimidines, barbituric acid and barbiturates. Purines. Uric acid. Oxo compounds. Structure of the carbonyl group. Chemical reactions of aldehydes and ketones: addition and condenzation reactions. Enol-oxo tautomerism and aldol dimerization of oxo compounds. The role of these reactions in biochemical processes. Oxidation and reduction reactions. Important oxo compounds: quinones, coenzyme Q and vitamin K. Classification and nomenclature of carboxylic acids. Acidity, salt formation. Homologous series of saturated and

SEMINAR (1 hr/week) Fire and safety precautions. Requirements for completion of the semester. Summary of organic chemical reactions. Chirality, optical isomerism.

PRACTICE (2 hrs/week – 8 weeks) No practice these weeks.

Amines.

Heterocyclic compounds.

Aldehydes, ketones, and quinones.

During weeks 4 to 8 students work in rotation and conduct one of the following experiments each week: I) Determination of pKa of a known concentration weak acid solution through the preparation of different buffers. II) Quantitative determination of Fe(II)-content by permanganometric titration

186

6.

7.

8.

9.

10.

11.

unsaturated carboxylic acids. Fatty acids. Dicarboxylic acids. Unsaturated and hydroxy carboxylic acids. Oxo acids, "ketone bodies". Derivatives of carbonic acid: urea, guanidine, creatine, phosphocreatine. Carboxylic acid derivatives: esters, thioesters, acyl halides, anhydrides, amides. Acylation reaction, acylating agents. Acid-catalyzed esterification and hydrolysis of esters. Soaps, detergents. Phosphoglycerydes. The structure of biological membranes. Classification and nomenclature of amino acids. Proteinogenic amino acids. Amphoteric character: isoelectric points. Essential amino acids, biological importance. Qualitative tests, preparation and separation of amino acids. Chemical properties. Peptides. Stereochemistry of the peptide bond. Principles of sequence analysis. Synthesis of peptides. Biological importance of peptides. Naturally occurring peptides. Important peptide hormones, analogues and peptide antibiotics. Structure and function of proteins. Physical and chemical properties, purification and classification of proteins. Qualitative tests. The threedimensional structure of proteins. Protein folding. Denaturation of proteins. Biological importance of proteins: transport, contractile, structural, nutrient, storage, defense and regulation proteins. Enzyme reactions. Classification of carbohydrates. Configuration. D-glucose, mutarotation, anomers. Cyclic structures. Chemical properties of monosaccharides: oxidation, reduction, formation of ethers and esters, formation of O- and N-glycosides. Important monosaccharides: aldoses and ketoses and their derivatives. Structure of disaccharides. Nonreducing disaccharides: sucrose. Reducing disaccharides: maltose, cellobiose, lactose. Oligosaccharides. Complex oligosaccharides. Polysaccharides: starch, glycogen, cellulose. Steroids. Classification of steroids. Cholesterol, Vitamins D2 and D3. Bile acids and their detergent effect. Steroid hormones. Corticosteroids: mineraloand glucocorticosteroids. Sex

Carboxylic acids. Substituted carboxylic acids.

measuring the redox potential. III) Photometric determination of iron. IV) Polarimetric determination of sugar. V) Quantitative determination of a protein by photometric method. VI) Quantitative determination of vitamin C content by bromatometric titration.

Carboxylic acid derivatives. Lipids.

Amino acids.

Peptides and proteins.

Monosaccharides.

Di- and polysaccharides.

Bioorganic chemistry: some chemical reactions of proteins and carbohydrates.



3.

14.

hormones. Structure and properties of nucleosides and nucleotides. Nucleic acid bases (uracil, thymine, cytosine, adenine, guanine). Nucleotide coenzymes. Nucleic acids: RNA and DNA. Hydrolysis, purification and properties of nucleic acids. Sequence analysis and synthesis of nucleic acids. Structure of DNA: double helix. Denaturation of DNA. Biological importance of nucleic acids. Important bioorganic compounds I. Water-soluble vitamins and their coenzymes. Fat-soluble vitamines. Hypo- and hypervitaminosis. Important bioorganic compounds II. Alkaloids, most important representatives. Antibiosis. Classification of antibiotics. Penicillin. Porphin-ring containing compounds. Protoporphyrin-IX and heme. Structure and biological importance of hemoglobin and myoglobin. Chlorophyll.

187 Steroids.

No practice these weeks.

Nucleosides, nucleotides, and nucleic acids.

Vitamins and coenzymes.

INTRODUCTION TO MEDICINE 1st semester LECTURE (1 hr/week) and PRACTICE (1 hr/week) Health Philosophy and Behavioral Medicine I. Modern concept of health and disease Health Philosophy and Behavioral Medicine II. What influences health? The development of disease: Causal models Health Philosophy and Behavioral Medicine III. Stress, coping, culture and lifestyle Preventive Medicine and Public Health I. Community diagnosis. Describing health problems Preventive Medicine and Public Health II. Analyzing healthproblems. Risk perception and risk communication Preventive Medicine and Public Health III. Basic theories of prevention and health education. The role of screening in prevention History of medicine I. Earliest medicine, antique times History of medicine II. Medicine in Middle Ages, Renaissance, Enlightenment History of medicine III. Science and technology in the19th-20th centuries Medical Ethics I. The Hippocratic oath Medical Ethics II. Ethics, morality and ethical theories Medical Ethics III. Basic principles of bioethics I. Medical Ethics IV. Basic principles of bioethics II

COMMUNICATION IN DENTISTRY 2nd semester

*

LECTURE (1 hour/week) 1. General prelude, the attitude, point of view of the curse, what is psychology, the relation between psychology and medicine. The necessity and traits of

PRACTICE (2 hours/week) 1. Introduction, technical details

188

*

2.

*

3.

*

4.

*

5.

*

6.

*

7.

*

8.

*

9.

*

10.

*

11.

*

12.

*

13.

*

14.

self-evaluation (self-image, assertive attitude, games people play, and it’s solution) Block in basic and biological elements of psychology (Sensation and perception). The psychology of social interactions (Basic elements of perception of people, schemas, stereotypes, attributions, the point of view of individual psychology) The psychology of social interactions (Basic elements of social behavior – the effect of people’s presence on human achievement, human groups and roles, the human mass’s symptom) The psychology of social interactions (submission, diffusion of responsibility, conformity to the great mass, the effect of minority on the majority) General psychology (attention, memory, imagination, human consciousness, thinking) Motivation (human needs, sexual-, human arousal) Human values (The base of values cognition, exploration -, self-respect and respecting people), the born-out syndrome (how to protect our mental health and harmony) Emotions (the evolution of them, theories of their functioning, the mechanism of facial feed-back, and it’s practical utility) The personality (definitions, theories, the role of nature and nurture) The psychology of human development (The importance, sections, approaches of it) The mechanism of human behavior, the possibilities to take effect on it. Basic element of learning processes (Respondent and classical conditioning, and it’s practical utility) The mechanism of human behavior, the possibilities to take effect on it. Basic element of learning processes (Complex –observational, and cognitive-behavioral – learning, and it’s practical utility) Summary of practical utilities of psychology – Questions and answers Free consultation – Questions and answers

2. Basic elements of communication

3. Factors which disturb the communicational process I.

4. Factors which disturb the communicational process II.

5. Verbal communication I.

6. Verbal communication II. 7. Factors which disturb the communicational process III.

8. Nonverbal communication I.

9. Nonverbal communication II. 10. Cultural presentation I.

11. Cultural presentation II.

12. Discussion

13. Test 14. Closing


189

SOCIAL POLICY FOR DENTAL STUDENTS 2nd semester LECTURE (1 hr/week) * *

Introduction to social policy. The aim and task of social policy. The basic values and principles of social policy

*

Social policy in welfare states

*

Social policy in the European Union I.

*

Social policy in the European Union II.

*

Social policy in developing countries

*

Poverty, deprivation, patterns of inequalities

*

Social policies toward families. Connections between demographics and social policy

*

Social policy of high-risk populations I. (immigrant, ethnicity)

*

Social policy of high-risk populations II. (unemployed, homeless)

*

Social policy of high-risk populations III. (disabled, chronic diseased)

*

Social policy of high-risk populations IV. (elderly)

*

The role of civil society, non-profit and non-governmental organizations in social policy

*

The future of social policy at international level. Final evaluation

NURSIG PRACTICE (SUMMER PRACTICE) 2nd semester Students may perform the emergency ambulance practice out of the University (in their country) at a dental emergency ambulance. In this case they have to submit an acceptance letter from the head of the chosen surgery. Students have to submit a certificate about the practice, containing a short evaluation. 2 x 35 hours (dental emergency ambulance) in July and August according to the group arrangement. Detailed description of the practice requirements: Getting to know the work of the Emergency Ambulance: - Observing the administrative tasks in connection with patient examination. (assignments, computerized patient admission, ambulance diary, patient records) - Procedure and practice of making a diagnosis - Getting to know and practicing the duties related to patient examination. - Observing the examination of X-ray results, and diagnosis making. - Getting to know the procedure of patients referral to certain departments. DENTAL MATERIALS AND TECHNOLOGY 3rd semester LECTURE (2 hrs/week)

PRACTICE (1 hr/week)

190 *

*

*

* *

*

* *

*

*

* * *

*

1. Introduction to dental materials science. Importance of dental material knowledge in dentistry. History of dental materials. International standards for materials used in dentistry (ISO, DIN etc.). Classification of dental materials based on structure and utilization 2. Types, classifications and applications of impression materials Presentation of elastic impression materials. 3. Examining, treating and preventive methods used in dentistry from technological point of view. Die materials and methods of model preparation 4 Burs and polishing instrument in dentistry. 5. Basic physical properties of materials. Test methods for materials in dental material science 6. Polymers used in dentistry (1st part). Practical aspects of polymers used in dentistry (2nd part) 7. Waxes. Occlusion papers and foils. Artificial teeth (acrylic and ceramic) 8. Filling materials and adhesive technologies. Dental cements and endodontic materials 9. Structure and properties of metals and alloys used in dentistry. Electroforming. Corrosion of metals 10. Investment, investment materials, metal casting. Processing of surfaces of dental appliances, polishing 11. Amalgam. Allergic reactions to dental materials 12. WRITTEN TEST 13. Materials used for porcelain-fused-tometal restorations. All-ceramic systems, composition, characteristics, processing 14. Course-evaluation

1-2. Carving a premolar and an upper central incisor tooth in plaster (white)

3-4. Impression materials in practice (impression gypsum products in practice, take impression from a coin, demonstration and use putty and wash materials)

5-6. Making impression with alginate on manikin, casting impression with gypsum. Basing the cast, five pointed trimming

7-8. The use of burs, cutting and polishing instruments

9-10. Dental polymers in practice (Pattern resin, preparing different forms: cube and cone etc.) 11-12. Waxes (bite registration on manikin, demonstration of waxes). Carving a central incisor and a molar in wax 13. Dental cements and filling materials in practice. Endodontic materials in practice

MEDICAL PSYCHOLOGY 3rd semester LECTURE/PRACTICE (1 hr/week)/(1 hr/week) I. The place of psychology in dentistry: biopsychosocial perspective, compliance II. Managing patient’s anxiety III. Clinical interviews, informing patients IV. Positive suggestions in dentistry V. Changing patient’s behaviour, persuasive communication VI. Dental psychosomatics ETHICS IN MEDICINE 3rd semester LECTURE (1 hr/week) and PRACTICE (1 hr/week) 1. 2. 3. 4.

Introduction, basic moral concepts Morals and law, short history of ethics Basic ethical theories and principles of bioethics Health and illness, informed consent

Curriculum 2014/2015 5. 6. 7. 8. 9. 10. 11. 12. 13.

191

Abortion Aids Euthanasia and suicide Impaired infants Animal experimentation Cloning Transplantation Patients’ rights Justice in medicine and public health

ORAL BIOLOGY 4th semester

* * * * * * * * *

* * * * *

LECTURE (1 hour/week) 1. The chemical composition of bone and teeth 2. The microstructure of teeth. The enamel, the dentine and the cementum 3. Formation and mineralization of hard tissues. Trace elements in teeth 4. The periodontium 5. The mastication, the deglutition and the speech 6. Measurement of the masticator force 7. The dental pulp 8. The biochemistry of fluoride ion 9. The pharmacology and the toxicology of the fluoride ion. The detrimental effects of fluoride on teeth 10. The taste and the olfaction 11. The microbial flora of the mouth in health and diseases 12. The saliva and the salivary glands 13. The calcium metabolism of bones and teeth 14. Consultation

PRACTICE (1 hour/week) 1. The chemical composition of bone and teeth 2. The bone and teeth mineralization. The trace elements in the teeth. 3. Microstructure of teeth (light microscopy) 4. The periodontium 5. The mastication, the deglutition and the speech 6. Measurement of the masticator force 7. The dental pulp 8. Research methods in dentistry 9. Literature search 10. The taste and the olfaction 11. The microbial flora of the mouth in health and diseases 12. The saliva and the salivary glands 13. The calcium metabolism of bones and teeth 14. Consultation

DENTAL BIOMETRY AND EVALUATION OF RESEARCH RESULTS 4th/6th/8th semester LECTURE (1 hr/week)

*

*

*

*

1. The importance and applications of statistics in dental sciences. Introduction to Mathematics, Part I. (definition of functions, different type of determinations and analysis) 2. Introduction to Mathematics, Part II. (set theory, combinatorics). Populations, probability, discrete variables and probability distributions 3. Continuous variables and frequency distributions. Normal distribution and the standard normal distribution. Parameters of distribution: arithmetic mean, median, mode, standard deviation, variance, standard error of the mean 4. Theoretical background of tests of significance: null hypothesis, level of significance, degree of freedom, possible errors

PRACTICE (1 hr/week) 1. Acquisition and representation of experimental data. Basics of computerized data processing. Representation of functions, different types of determinations and analysis 2. Examples for variables, populations, probability, discrete probability distribution 3. Examples for continuous variables and distributions. Normal distributions. Frequency distribution and preparing a histogram 4. Determination of parameters of distribution (arithmetic mean, median, mode, standard deviation, variance, standard error of the mean).

192 * * * * * * * * *

5. Parametric tests. Verification of normality. Student’s

t-test for paired samples 6. Student’s t-test for unpaired samples and the F-test for variances 7. Written test (I.) 8. Analysis of variance (ANOVA-test) 9. Non-parametric methods (Wilcoxon, Mann-Whitney U-test etc.) 10. Analysis of discrete variables: χ2 - test and Fisher exact test (contingency table) 11. Linear regression and the t-test of correlation. Linearization 12. Written test (II.) 13. Statistical analysis and data analysis in other statistical programs (Statistica 11)

Determination of probability 5. Applications of Student’s t-test for paired samples 6. Applications of Student’s t-test for unpaired samples and the F-test for variances 7. Written test (I.) 8. Applications of ANOVA 9. Applications for non-parametric methods 10. Applications of χ2 - test and Fisher exact test 11. Applications of linear regression and the t-test of correlation. Linearization problems 12. Written test (II.) 13. Evaluation of research results in other statistical programs (Statistica 11)

ODONTOTECHNOLOGY (summer practice) 4th semester 2 x 35 hours (Odontotechnology) in July according to the group arrangement. Detailed description of the practice requirements: 1. week 1. day – Drawing of teeth, carving teeth in wax (upper first incisor with root) 2. day – Drawing of teeth (praemolars and molars), carving teeth in wax (lower praemolar with root) 3. day – Carving teeth in plaster, learn to use handpieces and burs 4. day – Carving teeth in plaster, learn to use handpieces and burs 5. day – Use of impression materials on manikin. Making study casts, bite registration. Mounting the casts in the articulator – demonstration 2. week 1. day – Students laboratory: Mounting the casts in the articulator based on Bonwill triangle. Preparation of resin teeth, embedding them in plaster 2. day – Students laboratory: Mounting the casts in the articulator for gnathology practice, mixing and polishing base plate acrylic material. Visiting the dental technical laboratory (2 groups from 8.00 am, 2 groups from 10.00 am) 3. day – Students laboratory: Mounting the casts in the articulator for gnathology practice, mixing Pattern Resin, shaping a premolar tooth with burs in resin. Surgery: making a lower jaw alginate impression from each other, making a cast. 4. day – Students laboratory: making resin teeth, mounting resin teeth in gypsum block, mixing self curing acrylate, shaping a premolar tooth with burs in resin. 5. day – Students laboratory: Power point presentation about a dental technical technical procedure with own photos taking in the laboratory. Evaluation of model mounting. In the 2nd week students visit a dental technical laboratory in small groups (watch metal casting, ceramic works, model preparation, etc.) and make documentation about a technical procedure, which is presented in the last day of the summer practice. Pictures from the internet are not accepted! Conditions of accepting the practice for those who spend the practice outside the University Those students who don’t come to the Dental Faculty Students Laboratory for the practice, have to bring a certification from the head of the laboratory, where they stay for the practice, in which he/she declares that the student spent two weeks in the lab and fulfilled the above mentioned tasks. This statement must arrive to the Dean’s Office of the Dental Faculty till 20. August 2013. Students have to show their work prepared by themselves in the first week of Preclinical Course of Prosthodontics -

An upper middle incisor with root carved in wax, coronal size about 2-3cm A lower premolar with root carved in wax, coronal size about 2-3cm An upper premolar carved in white plaster (only coronal part) A lower molar carved in white plaster (only coronal part)

193 Curriculum 2014/2015 - A power point presentation about a dental technical procedure (4-7 slides) with photos made by the student. Pictures from the internet are not accepted! The presentation will be assessed; the mark will be counted among the results of the Preclinical Course of Prosthodontics. This is also a condition of accepting this course. MEDICAL SOCIOLOGY 4th semester

* * * * * * * * * * * * * *

LECTURE (1 hrs/week) What is sociology? Theories and perspectives in sociology. Role of behavioural sciences and medical sociology in medical education. Development, division, research fields of medical sociology. The sociology of dentistry The medical profession. Professional socialisation among medical students. Gender differences among medical students in their professional socialisation. Roleconflicts between family and professional roles. Doctor-patient interaction, models of the doctor-patient relationship. Parsons' concept of the sick- and doctor roles. Illness behaviour. The dental anxiety. Going to the doctor. Sociology of disability. Labelling and stigma. Illness as deviance, primary, secondary deviance. Deviance behaviours. Theories of deviance: biological, physical, psychological, sociological theories. Stratification and class. Social mobility. Social causes of illness, social patterns of illness (social aetiology of disease). Global inequality. Race, etnicity and migration. Social inequalities and health. Poverty, social exclusion and welfare. Families and intimate relationships. The life-course. Practice of medical sociological research methods. Strategy and research methods of medical sociology.

HUNGARIAN LANGUAGE I-IV. 1st semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) Introduction: general information about the language. The Hungarian alphabet, pronunciation and intonation. Greetings, notices. Getting acquainted: Who are you? Where are you from? Conjugation of the verb ‘to be’, subject form of the personal pronouns. What is where in Szeged? Asking questions. Question words, existential sentences. Definite and indefinite articles. Meeting students. The conjugation of verbs: present indefinite conjugation, singular forms. Cardinal numbers: telephone numbers and prices. Going shopping. The accusative form of nouns. Revision of grammar and vocabulary. Going to the cinema. Telling the time. Making an appointment. Plural forms of the verb (indefinite present tense). The postposition ‘elıtt’. TEST 1 A Sunday out: museum, theatre. The plural form of nouns and adjectives. Expressing possibility. The infinitive form. Buying cinema tickets. Practising the present tense indefinite conjugation. Some adverbial suffixes: -ba/-be (to, into), -ban/-ben (in) In a restaurant. Ordering a meal. Further adverbial suffixes: -hoz/-hez/-höz (to), -nál/-nél (at) General revision. TEST 2 Oral tests

2nd semester PRACTICE (4 hrs/week)

194 * * * * * * * * * * * * * *

My family:possesive suffixes, genitive structure. I have a…:Possesives+case endings. Expressing possession. What is your friend like:describing people. Calendar, dates. Revision TEST 1 Students life: review of indefinite conjugation. Transitive and intransitive verbs. Definite conjugation. Daily routine: verbal prefixes. Finding a flat: suffixes tól/tıl, hoz/hez/höz, ra/re. Compound nouns. Weather and seasons. General revision. TEST 2 Preparation for the oral exam. Oral tests

3rd semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) General revision. A weekend trip to Budapest. The comparative and superlative form of adjectives. Travelling by train. Sightseeing. Travelling abroad:revision of case endings and postpositions. Noun formation. I feel ill 'kell'+personalised infinitive. Reflexive pronouns. Health vocabulary. At the doctor's: kell, lehet, szabad, tilos. Suffix szor/szer/ször. Body parts. Revision TEST 1 Where were you in the summer: past tense conjugations. What happened? :past tense definite and indefinite. Time expressions. Revision of grammar and vocabulary. Revision of grammar and vocabulary. TEST 2 Preparation for the oral exam Oral tests

4th semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) Services: possesive suffixes in the plural. At the pharmacy. Private conversations:personal pronouns with case endings. Hat/het. Revision of past and present tense conjugation. Questions and question words. Word order and complex sentences. Grammar exercises and reading comprehension tasks. TEST 1 Practising role-play and picture description. Practising role-play and picture description. Grammar exercises and reading comprehension tasks. Grammar exercises and reading comprehension tasks. Words originating from the same root (kezd, kezdıdik etc.) Revision of grammar and vocabulary. Practising role-play and picture description.


195

SYLLABUSES PRE-CLINICAL MODULE - DENTISTRY PRECLINICAL COURSE OF PROSTHODONTICS I. 5th semester

* * *

*

*

LECTURE

PRACTICE

(1 hr/week)

(2 hrs/week)

1. Topics of prosthodontics. Prosthetic appliances 2. Main principles of tooth preparation 3. Tools and methods of tooth preparation. Veneer crowns

3. Preparation of resin teeth for veneer crown, knife edge finish line

4. How to avoid the harmful effects of tooth preparation

4. Preparation of embedded resin teeth for veneer crown, knife edge finish line.

5 Classification of crowns. Types and indications of different finish lines

5. Preparation of resin teeth int he manikin for veneer crown, knife edge finish line. Embedding removed natural tooth. WRITTEN ASSEESSMENT

6. Partial crowns. Preparation of 3/4 and 4/5 crown

6. Preparation of resin teeth int he manikin, 90° shoulder

7. Impression methods

7. Preparation of resin teeth (front), chamfer finish line.

8. Procedure of dental impressions

8. Preparation of resin teeth in the manikin, chamfer finish line

9. Digital impression

9. Preparation of resin teeth in the manikin, chamfer finish line

*

*

*

*

* *

10. Laboratory procedures. Model preparation I, II.. 11. WRITTEN TEST

* 12. Pulp protection. Provisional restorations *

1. Introduction the order of the laboratory order, instruments. Practicing the use of burs. 2. Preparation of resin teeth for veneer crown, knife edge finish line

13. How to build up a destroyed tooth? 14. Consultation

10. Preparation of resin teeth for partial crown (4/5) in the manikin 11. Preparation of resin teeth for partial crown (3/4) in the manikin 12. Upper central incisor preparation with chamfer as a practical exam 13. Provisional crown fabrication with prefabricated celluloid crown 14. Provisional crown fabrication with Scutan method

PRECLINICAL COURSE OF PROSTHODONTICS II. 6th semester

*

LECTURE

PRACTICE

(1 hr/week)

(4 hrs/week)

1. Construction of complete crowns – Cast metal crowns, veneer crowns. (Resin faced and porcelain fused to metal crowns.)

1. Tooth preparation for abutment (Chamfer margin design), the students should collect one rooted teeth for modelling a post and core.

196 *

2. Construction of complete crowns – Jacket crowns. (Resin and ceramic. Jacket crowns)

* 3. Construction of full crowns – fzkk ceranuc crowns *

*

*

*

4. Laminate veneers, shade selection

4. Impression making, construction of sectioned cast

5. Interim and definitive cementation of crowns. Removal of cemented fixed partial dentures

5. Impression making, construction of sectioned cast

6. Post retained crowns. Classification, construction, indications and contraindications. 1st Midsemester written test (Topic: Crowns, time: in the practice)

6. Mounting of the casts into articulator

7. Fabrication of post retained crowns. Clinical and laboratory steps

7. Mounting of the casts into articulator. MTO

8. Prefabricated posts: types, classification.

8. Construction of cast metal crown. Preparation of wax pattern

9. Fábián-Fejérdy classification of partial edentulousness

9. Construction of resin faced metal crown. Preparation of wax pattern

*

*

*

*

* *

2. Preparation of tooth 21 for complete crown, with chamfer margin design. Construction of temporary crown onto the prepared abutment 3. Preparation of tooth 37 for complete cast metal crown. Preparation of tooth 44 for complete veneer crown

10. Consequences of tooth loss. International classifications for edentulousness. Condition of abutment teeth – abutment selection 11. Definitions, nomenclature, classification related to fixed partial dentures. Retainers, pontics, materials for constructing fixed partial dentures, veneering methods 12. 2nd Midsemester written test (Fixed partial dentures, Post retained crowns) 13. Indications, differential indications, contraindications. Static, biomechanical and hygienic aspects. Procession of bridge construction.

10. Construction of resin faced metal crown. Preparation of wax pattern

11. Processing and polishing of the crowns 12. Construction of resin faced metal crown. Build up the veneer part of the crown 13. Tooth preparation for post-and-core, making a post-and-core, course assessment

* 14. Special bridges. Consultation

PRECLINICAL COURSE OF OPERATIVE DENTISTRY I. 5th semester

LECTURE

PRACTICE

(1 hr/week)

(4 hrs/week)

1. The topics of Operative Dentistry and its role in dental care. Anatomy of enamel, dentine and cement. Dental status.

1. Reception of instruments. Review of syllabus. The topics of Operative Dentistry. Maintaining the handpieces. The dental color code.

2. The definition of caries, histology, pathology. Diagnostics.

2. Types of burs, sizes. Hand instruments used in operative dentistry. Matrix systems and their usage. Black cavities, nomenclature.

*

*


197

3. Principles of cavity preparation and design. Black’s cavity classification and its modifications IVIth class. Retention forms.

3. Black. cl.I. preparation in artificial teeth. Learning the surface structures of teeth.

4. Structural pathology of teeth. Non-cariogenic laesions.

4. Practicing cavity preparation: Black cl. I., II. MO, OD, MOD (4)

5. Materials for restoring tooth. Classification, indications.

5. Practicing cavity preparation from mirror: Black cl. I., II. MO, OD, MOD (4)

*

6. Comparison of cavity preparation techniques. Contemporary cavity preparation and minimal invasive technique. Special cavity designs

6. Practicing cavity preparation with high speed handpiece: Black cl. I., II. MO, OD, MOD (4)

*

7. The definition of cavity lining, and base. Goals and theory.

7. Practicing cavity preparation: Black III., IV., V. (6)

8. Amalgam.

8. Practicing cavity preparation from mirror: Black III., IV., V. (6)

9. The classification of filling materials. Cements, compomers, ormocers, GIC

9. Zinc-phosphate cement, glassionomer cement, adhesive systems, composites. Preparation and usage.

10. The adhesive technique

10. Black cl. II. base fillings. Black cl. V. cavity filling with composite and GIC.

11. The classification of composites. Chemical background.

11. Black cl. I. cavity fillings. Pulp capping.

12. Written demonstration

12. Black cl. II. cavity fillings. Matrix systems.

13. Cervical laesions, Vth class cavities, sandwich technique, direct veneers.

13. Black cl. III. and IV. fillings. Finishing and polishing in practice.

14. Fractionated caries elimination. Healing the injured pulp. Direct and indirect pulp capping. (Students will get this lecture in electronic form.)

14. Practical exam.

*

*

* *

*

* *

*

PRECLINICAL COURSE OF OPERATIVE DENTISTRY Seminar I. 5th (1 hr/week) 1. Introduction 2. Development of caries 3. Caries classification 4. Black classification and cavity preparation 5. Cavity nomenclature 6. Minimal and non-invasive preparation 7. Materials used for direct restaurations 8. Amalgam filling 9. Composite filling 10. Matrix systems

198 11. Occlusion, articulation 12. Finishing and polishing 13. Test 14. Consultation PRECLINICAL COURSE OF OPERATIVE DENTISTRY II. 6th semester

*

LECTURE

PRACTICE

(1 hr/week)

(4 hrs/week)

1. Isolation in dentistry. Rubber dam. Matrix systems.

* 2. The anatomy of the pulp, and the pulp chamber. *

*

3. Trepanation and access cavity. Defining the working length in the root canal. Different methods. 4. The aims and principles of chemomechanical treatment.

* 5. Hand instruments for root canal treatment. *

*

*

3. Trepanation, access cavity. Theory and practice. 4. Instruments of endodontic treatment. Status and administration. 5. Locating root canal orifices, preparation of coronal third. Status and administration.

8. Rotary instruments for root canal treatment 9. Temporary seal of the root canal. Calciumhydroxide

9. Chemomechanical preparation of the root canals.

7. The chemical preparation- aims, principles and methods

10. The root canal treatment – different ways

* 11. Materials used: points and sealers

* 12. Lentulo technique and lateral condensation * 13. Restorations after root canal treatment *

2. Rubber dam isolation. Cavity preparation in plastic teeth. Direct and indirect pulp capping.

6. Length measurement. Different methods, performing and evaluating. Status and administration. 7. Chemomechanical preparation of the root canals. 8. Chemomechanical preparation of the root canals.

6. The mechanical preparation – aims, principles and methods

* *

1. Cavity preparation in plastic teeth. Performing an amalgam filling.

14. Inlays

10. Temporary root canal obturation. Ca(OH)2 in practice. 11. Materials for root canal obturation. Performing root canal obturation with lateral condensing technique. 12. Materials for root canal obturation. Performing root canal obturation with lateral condensing technique. 13. Materials for root canal obturation. Performing root canal obturation with lateral condensing technique.


199

PRECLINICAL COURSE OF OPERATIVE DENTISTRY Seminar II. 6th (1 hr/week) 1. Introduction 2. Pulpal considerations 3. Macro- and microscopy of the endodontium 4. Pulpal and periapical diseases 5. RCT - indications and contraindication 6. RCT- instruments 7. Length measurement 8. RCT - materials 9. RCT - techniques 10. RCF - materials 11. RCF - techniques 12. Retreatment 13. RCT - Coronal restauration 14. Test GNATOLOGY 5th semester LECTURE

PRACTICE

(1 hr/week)

(3 hrs/week) 1. Introduction. Instruments and materials. Marking reference lines and points on the study cast and on the mounted lower cast. Marking the centric contacts on the upper mounted cast. Cutting off the occlusal surface of the mounted lower cast. Re-tracing the markings on the occlusal surface of the lower cast 2. Forming mandibular buccal cones. Marking reference lines and points on the mounted upper cast. Cutting off the occlusal surface of the mounted upper cast 3. Re-tracing the occlusal surface of the upper cast. Re-tracing the markings on the occlusal surface of the upper cast. Forming maxillary buccal cones. Forming the buccal ridges of mandibular buccal cusps 4. Forming the buccal ridges of maxillary buccal cusps. Shaping the triangular ridges of the maxillary buccal cusps

*

1. Introduction to Gnatology, it’s significance in dentistry. Functional units involved in mastication. Anatomical terminology of the mouth

*

2. Morphology of osseous structures involved in mastication and the temporo-mandibular joint

*

3. Basics of occlusal anatomy of the teeth and dental-arches

*

4. Occlusal contacts in central occlusion. Orientation in the oral cavity

*

5. Masticatory muscles, their function and innervation

*

6. WRITTEN TEST

*

7. Specific positions of the mandible

*

8. Mandibular movements, tooth guidance. Dynamics of occlusal relationships, bordermovements, mandibular movement envelope

*

9. The process of chewing. Occlusal relations in natural dentition

*

10. Aticulators (arcon, non-arcon types)

5. Forming the mesial and distal cusp ridges of the maxillary and mandibular buccal cusps 6. Forming the maxillary lingual cones and the cusp ridges of the maxillary lingual cusps 7. Shaping the lingual surfaces and triangular crests of the maxillary lingual cusps 8. Forming the mesial and distal marginal ridges of the maxillary posterior teeth. Building up the triangular ridges of the mandibular buccal cusps 9. Building up the mandibular lingual cones. Forming the lingual surfaces and the triangular ridges of the mandibular lingual cusps 10. Forming the mesial and distal cusp ridges of the mandibular lingual cusps. Face-bow and it’s use

200 *

11. Mounting the casts in the articulator, articulator-programming, face-bow and it’s usage

*

12. WRITTEN TEST

*

13. Modification of occlusion in adults. Christensen phenomenon

11. Forming the mesial and distal marginal ridges of the mandibular posterior teeth. Face-bow and it’s use 12. Completing the mandibular and maxillary occlusal surfaces. Evaluating the completed cusps and ridges, 13. Forming the occlusal surface of a molar tooth by oneself

14. Theories of occlusion in artificial dentition DENTIST-PATIENT COMMUNICATION 5th, 6th semester LECTURE, PRACTICE (8 hrs in block) *

The significance of dentist-patient communication, introduction of consultation models. Learning the importance of basic ethical principles expected in any dentist-patient communication. Preparing for project work. Group work I.: 7 tasks of Pendleton in consultation, situation practice, stopping an attack, the art of not saying, preparing for video-recording. Group work II.: defining personality marks by using Myers-Briggs Type Indicator, behaviour, personal relations, stress situations, reactions, leadership style, problem solving methods. Evaluation of the video-recordings of students’ private consultation with patients in the surgery room. Following the consultation the evaluation of the whole group according to the Pendleton rules.

GENERAL AND DENTAL RADIOLOGY 5th semester

*

LECTURE

PRACTICE

(2 hrs/week)

(2 hrs/week)

1. The basics of the general radiology I.

1. Investigating methods of general radiology I.

*

2. The basics of the general radiology II.

2. Investigating methods of general radiology II.

*

3. Investigating methods of dental radiology, imaging techniques in dental radiology I. The anatomy of the teeth and jaws in the dental radiology I. 4. Investigating methods of dental radiology, imaging techniques in dental radiology II. The anatomy of teeth and jaws in the dental radiology II. 5. Investigating methods of dental radiology, imaging techniques in dental radiology III. The anatomy of teeth and jaws in the dental radiology III. 6. Radiographic diagnostic methods for the malpositioned teeth and eruption anomalies of the teeth. WRITTEN ASSESMENT 7. Radiographic diagnostic methods in the operative dentistry 8. Radiographic diagnostic methods for the inflammation in jaws 9. Radiographic diagnostic methods for the periodontal diseases 10. Radiographic diagnostic methods for the dentogene sinusitis, sialolyts

3. The occlusal, panoramic, periapical bite-wing radiographs taking

7. The occlusal, panoramic, periapical bite-wing radiographs taking 8. The occlusal, panoramic, periapical bite-wing radiographs taking 9. The occlusal, panoramic, periapical bite-wing radiographs taking 10. The occlusal, panoramic, periapical bite-wing radiographs taking

11. Radiographic diagnostic methods in maxillo-

11. The occlusal, panoramic, periapical bite-wing

*

*

*

* * * * *





201

facial traumatology

radiographs taking

12. Radiographic diagnostic methods for the cysts in jaws. WRITTEN ASSESMENT 13. Radiographic diagnostic methods for the tumors in jaws

12. The occlusal, panoramic, periapical bite-wing radiographs taking 13. The occlusal, panoramic, periapical bite-wing radiographs taking

* BIO- AND ALLOPLASTIC MATERIALS IN DENTISTRY 5th semester LECTURE (2 hrs/week) * * * * * * * * * * * * * *

1. Introduction to biomaterials science. Historical overview. Classes of biomaterials used in dentistry and medicine 2. Bulk and mechanical properties of materials and investigation methods (chemical bonds and structure, mechanical testing methods) 3. Surface characteristics of materials and investigation methods (contact angle, ESCA, SIMS, SEM, IRS, STM, AFM) 4. Metals (stainless steels, Co-Cr alloys, Ti alloys) 5. Dental amalgams. Corrosion of metals. Hydrogels, bioresorbable and bioerodible materials 6. Written test (I.) 7. Polymers, types of polymers, polymerization, mechanical and thermal properties 8. Ceramics, glasses and glass-ceramics (bioinert, calcium-phosphate ceramics, bioactiv glasses) 9. Composites and natural materials (proteins, polysaccharides, polynucleotides) 10. Host reactions to biomaterials and degradation of biomaterials in the biological environment 11. Titanium implants and biointegration. Thin films, coatings and fabrics 12. Written test (II.) 13. Testing biomaterials (in vitro, in vivo assessment and animal models). Biocompatibility and biomechanical tests 14. Consultation

PATHOPHYSIOLOGY 5th semester LECTURE

SEMINAR/PRACTICE

Introduction to Pathophysiology; Inflammation I.: Definition, causes, mediators and signs of acute inflammation. Regulation and outcome of acute inflammation.

Safety regulations. Review of physiologic background of circulation and normal ECG. In the practice room: Registration and analysis of ECG. Determination of spirometric parameters.

Inflammation II.: Chronic inflammation. Local and generalized reactions of inflammation: fever, inflammatory pain.

Seminar: Inflammation I. (Lecture topic of the 1st week). In the practice room: Registration and analysis of ECG. Determination of spirometric parameters.

Pathophysiology of leukocytes I.: Immunology: In vivo allergic reactions, autoimmunity, immunodeficiency.

Seminar: Inflammation II. (Lecture topic of the 2nd week).

Endocrinology I.: Disturbances of endocrine regulation. Diseases of hypothalamus, hypophysis and thyroid gland. Hyperparathyreoidism.

Seminar: Pathophysiology of leukocytes I.: Immunology (Lecture topic of the 3rd week).

Endocrinology II.: Hypoparathyreoidism. Diseases of adrenal (cortex and medulla) gland.


202 Starvation and obesity. Diabetes mellitus, hypoglycemia Diabetes mellitus causes, types, clinical signs, pathogenesis and consequences. Hypoglycemia Cardiovascular system I.: Pathophysiology of plasma lipoprotein metabolism. Development of atherosclerosis.

Seminar: Endocrinology II. (Lecture topic of the 5th week).

Seminar: Starvation and obesity. Disturbances of carbohydrate metabolism (Lecture topic of the 6th week).

Cardiovascular system II.: Seminar: Cardiovascular system I. Pathogenesis and consequences of atherosclerosis. (Lecture topic of the 7thweek). Primary and secondary hypertension. Cardiovascular system III.: Pathophysiology and ECG of acute coronary syndromes: angina pectoris, myocardial infarction

Seminar: Cardiovascular system II. (Lecture topic of the 8th week).

Cardiovascular system IV.: Congenital heart diseases. Mitral, aortic stenosis and regurgitation. Compensated and decompensated heart function, Heart failure.

Seminar: Cardiovascular system III. (Lecture topic of the 9th week).

Peripheral circulatory diseases: Volume depletion. Syncope. Circulatory shock (development, stages). Multiple organ dysfunctions in shock.


Pathophysiology of salt-water balance I.: Volume excess, hyper- and hyponatremia, hyperand hypocalcemia

Seminar: Peripheral circulatory disease (Lecture topic of the 11th week).

Pathophysiology of salt-water balance II.: Hyper- and hypokalemia, disturbances of trace elements and vitamins.

Seminar: Pathophysiology of salt-water balance I (Lecture topic of the 12th week).

Cardiovascular system V.: Disturbances of electrical impulse generation and conduction.

Seminar: Pathophysiology of salt-water balance II (Lecture topic of the 13th week).

6th semester LECTURE Pathophysiology of kidney diseases I.: Proteinuria, hematuria, glycosuria, ketonuria, pyuria, bacteruria, polyuria, oliguria and anuria.

SEMINAR/PRACTICE Safety regulations. Seminar: Thermoregulation. (Please download and study the material from our website or coospace before class).

Pathophysiology of kidney diseases II.: Nephrotic and nephritic syndrome, pyelonephritis, kidney stones. Acute and chronic renal failure.

Seminar: Kidney diseases I. (Lecture topic of the 1st week). In the practice room: Investigation of urine and renal function: proteinuria, hematuria, pyuria, hemoglobinuria, ketone bodies, urobilinogen, urine sediment and casts.

Pulmonary diseases I: Abnormal breathing patterns, dyspneas. Obstructive pulmonary diseases: CODP, asthma bronchiale, cystic fibrosis.

Seminar: Kidney diseases II. (Lecture topic of the 2nd week). In the practice room: Investigation of urine and renal function: proteinuria, hematuria, pyuria, hemoglobinuria, ketone bodies, urobilinogen, urine sediment and casts.


203

Pulmonary diseases II: Restrictive pulmonary diseases (pleural disorders, pulmonary edema, embolism, hypertension), hypoxias, respiratory failure.

Seminar: Pathophysiology of pulmonary diseases I. (Lecture topic of the 3rd week).

Disturbances of acid-base metabolism: Respiratory acidosis and alkalosis. Metabolic acidosis and alkalosis.



Seminar: Disturbances of acid-base metabolism (Lecture topic of the 5th week).

Gastrointestinal diseases II.: Diseases of absorption, diarrhea, constipation. Intestinal obstruction. Acute and chronic pancreatitis.

Seminar: Gastroenterology I. (Lecture topic of the 6th week).

Diseases of liver and biliary tract: Diseases of Seminar: Gastroenterology II. (Lecture topic of the 7th bilirubin metabolism: hemolytic, hepatocellular and week). obstructive jaundice. Causes, pathogenesis and consequences of hepatic cirrhosis. Pathophysiology of leukocytes: Leucopenia. Proliferative diseases: reactive and malignant diseases (leukemias, lymphomas).

Seminar: Pathophysiology of liver diseases (Lecture topic of the 8th week).

Red blood cell diseases I.: Polycytemias, Anemias - ineffective erythropoesis.

Seminar: Pathophysiology of leucocytes II. (Lecture topic of the 9th week).

Red blood cell diseases II.: Anemias due to blood loss, hemolysis. Hemostasis I.: Bleeding disorders (platelet disturbances).

Seminar: Red blood cell diseases I. (Lecture topic of the 11th week).

Hemostasis II.: Bleeding disorders (vascular, clotting factor disturbances), thrombosis and embolism.

Seminar: Red blood cell diseases II. Hemostasis I. (Lecture topic of the 12th week). In the practice room: Determination of WBC, RBC, platelet, eosinophyl and reticulocyte count. Staining and analysis of blood smear.

Pathophysiology of the CNS I.: Multiple sclerosis, neurodegenerative diseases: Alzheimer’s, Parkinson’s and Huntington’s disease. Pathogenesis of psychiatric disorders.

Seminar: Hemostasis II. (Lecture topic of the 13th week). In the practice room: Determination of WBC, RBC, platelet, eosinophyl and reticulocyte count. Staining and analysis of blood smear.

Pathophysiology of the CNS II.: Circulatory diseases of the CNS. Cerebral edema. Pain, headaches, seizures and epilepsy.


PRECLINICAL COURSE OF ORAL SURGERY 6th semester

* * * *

LECTURE

PRACTICE

(2 hrs/week)

1 hr/week)

1. History of oral surgery. Sepsis. Antisepsis 2. Local anaesthesia in dentistry. Anatomical and pharmacological considerations 3. Complications of anaesthesia. Methods of local anaesthesia

Practice in local anaesthesia in dentistry and tooth extraction. Related problems. 10 simple extractions, assistance to dentoaveolar surgery.

4. Indications of tooth extraction. Simple tooth

204 * * * * * * * * * *

extractions 5. Complications of tooth removal. Normal and disturbed wound healing 6. Misplaced and impacted teeth 7. Opening of the maxillary sinus and its management 8. Dental inflammations 9. Endodontic surgery. Surgical procedures related to orthodontic treatment 10. Trismus 11. Clinicopathology of cysts 12. Dentoalveolar trauma 13. Written exam 14. Discussion

ORAL SURGERY (summer practice) 4 x 35 hours, four weeks in July/August. Detailed description of the practice requirements: Practice in local anaesthesia in dentistry and tooth extraction. Related problems. 10 simple extractions, assistance to dento-alveolar surgery. ADVANCED IMAGING TECHNIQUES IN DENTISTRY 6th semester

* * * *

LECTURE

PRACTICE

(1 hr/week)

(1 hr/week)

1. The basics of general radiology I. Modern imaging technics I. 2. The basics of general radiology II. Modern imaging technics II. 3. Interpretation in the dento-maxillo-facial radiology 4. Radiographic diagnostic methods in the operative dentistry

*

5. Modern digital imaging technics.

*

6. Modern digital imaging technics in the dental practice, Digora system 7. Nuclear medicine in dentistry 8. Radiographic diagnostic methods for the periodontal diseases 9. Modern imaging technics in the implantological diagnosis and in therapy

* * * * * * * *

10. Cone Beam CT in dentistry 11. Using of lateral cephalometric projection in the dental practice 12. WRITTEN ASSESSMENT 13. The practical questions of the mobile X-ray machine’s application 14. Consultation

PUBLIC HEALTH 5th semester LECTURE (1 hr/week)

Making of one digital image during the practices Knowledge of radiographic anatomy of the teeth and the jaws.

Curriculum 2014/2015 * * * * * * * * * * * * *

205

The history of public health. The aim and scope of public health. The levels of prevention. Measuring the health of a population I. Measuring the health of a population II. Measuring the health of a population III. Epidemiology of chronic diseases – cardiovascular diseases. Epidemiology of chronic diseases – tumors. Epidemiology of chronic diseases – respiratory and musculoskeletal diseases. Epidemiology of chronic diseases – gastrointestinal and metabolic diseases. Dental screening, effective dental prevention, health education and health promotion. Epidemiology of suicide and accidents. Epidemiology of smoking. Epidemiology of alcohol and drug consumption. Structure and operation of health systems.

PUBLIC HEALTH 6th semester LECTURE (1 hr/week – 7x2 hrs) * General epidemiology of infectious diseases. Epidemiology of airborne and enteric diseases in dental practice. * * Epidemiology of hematogenic, cutaneous, and sexually transmitted diseases in dental practice. * * Epidemiology of zoonoses, transmissible spongiform encephalopathy. Epidemiology of health care associated infections. * * Nutrition in public health. Disorders of under- and overnutrition. * * *

Food quality and safety.

PRACTICE (1 hr/week – 7x2 hrs)

Sterilization, disinfection, disinsection, deratisation. Practical aspects of vaccination. Infection control and hand hygiene in dental practice. Dietary guidelines and the prevention of dietrelated chronic diseases. Air pollutants, water pollutants and their effects on human health.

-

* Environmental epidemiology; sewage, soil pollutions; hazardous waste, waste management in dental office. * * Occupational diseases caused by chemicals and chemical safety in dental care.

Occupational hazards in dental care. Practical aspects of occupational and microenvironmental toxicology in dentistry. -

HUNGARIAN LANGUAGE V. 5th semester Week 1. 2. 3. 4. 5. 6. 7. 8. 9.

Topics Human dentition. Types of teeth Dental Specialties Taking medical history Communication in dental practice Interviewing the patient. Examining the patient Written test Autumn break Basic dental instruments

Practice/ Skills Vocabulary practice Word building Lexical drill Question-answer practice Dialogues Role-play

Reading comprehension

206 10. 11. 12. 13. 14. 15.

Preventive dentistry Brushing techniques Dental floss Fluoride – a decay fighter Written test Oral assessment

Role-play Vocabulary practice Lexical drill Dialogue

HUNGARIAN LANGUAGE VI. 6th semester Week 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15.

Topics Dental diseases Dental plaque Periodontal diseases Gingivitis Dental caries Restorative materials. Written test Spring break Anaesthesia in dentistry Complications of anaesthesia Extractions. Scaling techniques Bleaching techniques Written test Oral assessment

Practice/ Skills Reading comprehension Vocabulary practice Lexical drill Word building Dialogues Role-play

Reading comprehension Vocabulary practice Dialogues Lexical drill Role-play

PHARMACOLOGY 5th semester LECTURE (2 hrs/week) 1. General pharmacology, pharmacodynamics 2. Pharmacokinetics 3. Adverse effects of drugs 4. Drug interactions 5. Autonomic nervous system: Introduction 6. Cholinergic and Adrenergic agonists 7. Cholinergic and Adrenergic antagonists 8. Local anaesthetics 9. Chemotherapy and Antibiotics I 10. Chemotherapy and Antibiotics II 11. Chemotherapy of viral and fungal infections 12. Non-steroidal anti-inflammatory drugs 13. Antihelmintic drugs, treatment of protozoal infections 14. Antiseptis and desinfectants 15. Agents acting on the blood PHARMACOLOGY 6th semester LECTURE (2 HRS/WEEK) 1. Sedative-hypnotic drugs, anxiolytics 2. Opioid and non-opioid analgesics 3. General anaesthetics, antiepileptic drugs 4. Antiparkinson drugs, centrally acting muscle relaxants 5. Antidepressive drugs, Antipsychotic drugs 6. Cardiotonic drugs 7. Antiarrhythmic drugs 8. Pharmacology of atherosclerosis, antihypertensive drugs

PRACTICE (1 hr/week) Prescription writing Pharmacodynamic and kinetic examples Computer Lab: Drug-receptor interaction Examples for drug interactions MTO: General Pharmacology Computer Lab: Sympathomimetics Computer Lab: Sympatholytics Local anaesthetics in dental practice MTO: Autonomic nervous system and local anaesthetics Prescription writing Prescription writing To recapitulate chemotherapy To recapitulate chemotherapy Prescription writing Haemostatic drugs

PRACTICE (1 HR/WEEK) Drugs of convulsive types, psychostimulants Consultation (opioids) Prescription writing Interactions with centrally acting drugs MTO-CNS drugs Computer Lab: CVS drugs Computer Lab: CVS drugs Consultation: CVS drugs

Curriculum 2014/2015 9. 10. 11. 12. 13. 14. 15.

Antianginal drugs, diuretics Treatment of diabetes and hyperthyrosis Hormons, vitamins Gastrointestinal pharmacology Toxicology Agents affecting bone mineral homeostasis Introduction to immunpharmacology, steroidal drugs

207 Consultation: CVS drugs MTO-CVS Prescription writing Prescription writing Consultation: Toxicology Prescription writing Introduction to herbal drugs in dental practice

General and Systemic Pathology for Dentistry Students 5th semester Lecture 3 hours/week

1

Organ demonstration 1 hour/week

Pathology of cellular injury and death. Cellular Actual postmortem cases are adaptations of growth and presented to the students on differentiation. Postmortem changes each week

Practice 2 hours/week Autopsy/ Histology of the cellular injury and death

Calcification. Oedema, hyperaemia, congestion. Haemorrhage

2

Thrombosis. Embolism. DIC. Shock. Consequences of vascular occlusion. Infarction. Acute inflammation I.

Actual postmortem cases are presented to the students on each week

Autopsy/ Histology of the cellular injury and death

Acute inflammation II.


Autopsy/Histology of degeneration


Autopsy/Histology of degeneration


Autopsy/Histology of the circulation


Autopsy/Histology of the circulation

Pathology of prolonged bed rest. Pathology of Actual postmortem cases are smoking. Pathology of alcoholism. Pathology presented to the students on of obesity. Diabetes. each week

Autopsy/Histology of the inflammation

3 Pathology of chronic inflammation. Tissue repair. Wound healing. Immunopathology I 4

Immunopathology II. AIDS. Pathology of transplant rejection. Neoplasia I.

5 Neoplasia II. Carcinogenesis. 6 Clinical aspects of neoplasia.

7 Pathology of aging. Protein-energy malnutrition. Cystic fibrosis. Marfan's syndrome. Amyloidosis. Vascular pathology I. 8


Autopsy/Histology of the inflammation


Autopsy/Histology of the tumors

Vascular pathology II. Vascular pathology III. Heart failure. 9 Pathology of the heart I.

208 Pathology of the heart II. 10 Essential hypertension. Pathology of the kidney I. Pathology of the kidney II. 11


Autopsy/Histology of the tumors


Autopsy/Histology of the cardiovascular system


Autopsy/Histology of the cardiovascularsystem


Autopsy/repetion


Autopsy/repetion

Pathology of the kidney III. 12

Tumours of the kidney. Pathology of the urinary bladder. Pathology of the lung I. Pathology of the lung II. Pathology of the lung III.

13

14

Tumours of the lung. Upper respiratory airway diseases. Diseases of the oral cavity. Pathology of the oesophagus. Pathology of the stomach and duodenum. Oral and Maxillofacial Pathology for Dentistry Students 6th semester Lecture 2 hours/week

Organ demonstration 2 hours/week

Actual postmortem cases are presented to the students on Pathology of the liver. each week Actual postmortem cases are 2 Pathology of the biliary tract. Pathology of the presented to the students on each week pancreas. Actual postmortem cases are 3 presented to the students on Pathology of the bowels. each week Actual postmortem cases are 4 presented to the students on Pathology of the peritoneum. each week Actual postmortem cases are 5 presented to the students on Hemopathology II. each week Actual postmortem cases are 6 presented to the students on Hemopathology III. Neuropathology I. each week Actual postmortem cases are 7 presented to the students on Neuropathology II. each week Actual postmortem cases are 8 presented to the students on Neuropathology III. each week Actual postmortem cases are 9 presented to the students on Immunopathology. each week Actual postmortem cases are 10 Pathology of the male genital tract. presented to the students on 1

Practice 2 hours/week

Autopsy/Histology of urinary tract Autopsy/Histology of urinary tract Autopsy/Histology of the respiratoty tract Autopsy/Histology of the respiratoty tract Autopsy/Histology of gastrointestinal tract Autopsy/Histology of gastrointestinal tract Autopsy/Histology of the hematopoetic and the lymphoid system Autopsy/Histology of the hematopoetic and the lymphoid system Autopsy/Histology of the genital system Autopsy/Histology of the genital system


209 each week

11 Pathology of the female genital tract I. Pathology of the breast. 12 Pathology of the female genital tract II. 13 Tumors of the soft tissue. Pathology of the bones and joints. 14 Pathology of the endocrine glands.

Actual postmortem cases are presented to the students on each week Actual postmortem cases are presented to the students on each week Actual postmortem cases are presented to the students on each week Actual postmortem cases are presented to the students on each week

Autopsy/Histology of the nervous system

Autopsy/Histology of the nervous system Autopsy/Histology of the endocrin system Autopsy/Histology of the endocrin system

INTRODUCTION TO SURGERY 5th semester Lecture 1 hour/week * The history of Surgery * The inspection and preparation of the surgical patient before the operation * Blood circulation in the schock state * Clinical Aspects of Schock * Blood replacement and the basics of transfusion * Asepsis and antisepsis * Wound formation and unification, tools of haemostasis in surgery * Types, healing and treatment o wounds * Postoperative complications and nourishment * Surgical infections, modenr antibiosis * Basics of surgical oncology * Surgical demonstration * Consultation * Test

SURGERY 8th semester Lecture (2 hours/ week) * The complex treatment of the breast cancer * The Surgery of the abdominal wall * Thoracic surgery * The surgery of the oesophagus * The surgery of the stomach * The surgery if the bile system and the pancreas * The surgery of the liver * The surgery of the large intestine and rectum * The surgery of the acute abdomen (appendicitis, ileus, perforations) * Vascular surgery * Cardiac Surgery * Organ Transplantation * Test

Practice ( 1 hour/week) The students can comply their surgical practice at weekends divided in 5-class periods at the Outpatient Department of the Surgical Clinic. There the students can participate in examining patients, can discuss the examination process and treatments, can take part of care of wounds and in the acute surgical interventions.

210 SYLLABUSES CLINICAL MODULE - DENTISTRY ENDODONTICS 7th semester LECTURE (1 hr/week) * * * * * *

1. Subjects and fields of endodontics. Anatomy, physiology, histology of the pulp tissue. The function of the pulp. Short introduction to the pathology of the pulp. 2. Treatment possibilities of the pulpal/periapical disease. Success rates. Circumstances affecting the outcome of the treatment. 3. Examination of patient with endodontic problems (Anamnesis, clinical examination) 4. Diagnostics in endodontics 5. Treatment planning in endodontics 6. The causes of pulpal diseases. Classification (old and new nomenclature). The indications and contraindications of root canal treatment.

*

7. Diseases with a pulpal etiology. Gangrena Simplex et Complicata

* * * * *

8. Failures during shaping and obturation of the root canal. 9. Advanced root canal obturation techniques. 10. Irrigation (Protocols, chemicals, instruments) 11. Retreatment, revision 12. WRITTEN DEMONSTRATION 13. Resorption

ESTHETICS OF THE FACE 7th/9 th semester LECTURE 1.Esthetics of the face, characteristics and factors determining the smile 2.Introduction to facial anatomy and esthetics 3.Historical overview 4. Dental esthetics, pink and white harmony 5. Surgical aspects of facial surgeries 6. Prevailing of esthetic aspects during the planning process of orthognathic surgery 7. Dysgnathic surgeries 8. Developmental disorders and their treatment 9. Injuries and complications 10. Scartreatment, after care, laser therapy 11. Dermatologicalaspects 12. Epithesis, facial prostheses 13. Ambulatory interventions-Botox, injectable fillers, hyaluronic acid ESTHETIC DENTISTRY I. 7th/9 th semester LECTURE (1 hr/week) * *

1. Introduction to esthetics: Extra oral factors, smile line and incisal edge, red-white harmony. Planning, diagnostic wax up. 2. Diagnostic wax up: Planning, fabrication of diagnostic wax model, controlled preparation

Curriculum 2014/2015 * * * * * * *

*

* *

3. Red-white harmony: optimal soft tissue esthetics and its realization 4. Marketing and Economy 5. Implant esthetics: Single implants in the front region 6. Magnification in dentistry 7. Communication and documentation: Methods of patient-doctor, technician-doctor communication, necessity and failures. 8. Adhesive post in root canal treated teeth, restorations with adhesive splinting Esthetic restoration in root canal treated teeth, composite based direct restorations 9. Bleaching: The chemical reaction and its theories. Techniques and ways to do it. Effects of light, heat and ultrasonic waves. Why, when and how? Ethical questions. 10. Ceramics: Classification and production. Bonding or cementing, chemical relations. The surface of ceramic and its pre-treatment. 11. Front restorations: Press ceramics, its advantages and disadvantages. Planning, preparation, bonding. 12. CAD/CAM: History, indications, failures. The way of preparation. 13. Ceramics in the molar region: Inlays, crowns, bridges. What, how, why, when?

ESTHETIC DENTISTRY II. 8th/10 th semester PRACTICE (1 hr/week) * * * * * * * * * *

1. Color theory (lecture) 2. Layering composite: Anatomic stratification (lecture) 3-4. Stratification technique (practice) A practice on front teeth 5. Stratification technique („accessory” Practice) 6. Shoulder preparation for full ceramic crowns (lecture) 7-8. Shoulder preparation for ceramic crowns (practice) 9. Veneers: Ceramic and composite (planning, perparation, bonding) 10-11. Veneer preparation 12. Manufacturing of temporary prostheses 13. Consultation

INFECTION CONTROL IN DENTISTRY 7th semester LECTURE and PRACTICE (Lecture 1 hr/week, practice 1 hr/week) * * * * * *

1. Introduction into infection control. Why does the dentist need infection control? 2. Introduction to infectious diseases 3. Blood-borne pathogens 4. Oral and respiratory diseases 5. Disinfection 6. Sterilization

211

212 *

7. Instrument processing, surfaces and equipment asepsis

* *

8. Laboratory and radiology asepsis 9. Aseptic techniques

* * * *

10. 11. 12. 13.

Protection of dental health care personnel. Immunization, protective barriers Waste management. Managing chemicals safely in the office Management of the office safety program. Work organization. Ergonomics Hospital infections

ORAL SURGERY I. 7th semester Practice 3 hrs/week Practice in basic dentoalveolar surgery: - apicectomy - excochleation - incision - bone correction Minimal requirements of semester 5 simple tooth extraction. ORAL SURGERY II. 8th semester Practice 3 hrs/week Practice in basic dentoalveolar surgery: apicectomy excochleation incision bone correction Minimal requirements of semester 5 simple tooth extraction. INTERNAL MEDICINE 7th semester

* * * * * * *

* * * *

LECTURE (3 hrs/week) Examination of the heart Carditis, valvular heart disease Diagnostic methods in internal medicine Diagnostic methods in internal medicine Arrhythmias Ischaemic heart disease, myocardial infarction Acute heart failure Acute heart failure. Therapy Chronic heart failure Chronic heart failure. Therapy Hypertension Hypertension. Therapy Disorders of the peripheral arteries and veins Methods and specific questions of the anticoagulant therapy Acute respiratory insufficiency Chronic pulmonary disorders Chronic pulmonary disorders. Therapy Diabetes mellitus Diabetes Mellitus. Therapy Acute and chronic renal disorders Acute and chronic renal disorders. Therapy

PRACTICE (2 hrs/week) Examination of the heart Carditis, valvular heart disease Diagnostic methods in internal medicine Arrhythmias Ischaemic heart disease, myocardial infarction Acute heart failure Chronic heart failure Hypertension Disorders of the peripheral arteries and veins Methods and specific questions of the anticoagulant therapy Acute respiratory insufficiency Chronic pulmonary disorders Diabetes mellitus Acute and chronic renal disorders

Curriculum 2014/2015 * * *

213

Hyperlipidaemia, hyperuricaemia Anemias Haemostatic disorders Leukaemias, lymphomas Principles of antibiotic therapy Consultation

Hyperlipidaemia, hyperuricaemia Anemias Haemostatic disorders Leukaemias, lymphomas Principles of antibiotic therapy Consultation

8th semester (15 weeks)

*

LECTURE (4 hrs/week) Esophageal disorders

*

Diseases of the stomach

* * *

Diarrhoea, constipation Inflammatory bowel diseases Disorders of the gallbladder and the biliary tract

* * *

Diseases of the liver Disorders of the pancreas Gastrointestinal tumors

* *

Disorders of the thyroid gland Diseases of the hypophysis and the parathyroid gland Diseases of the adrenal gland Degenerative, and autoimmune connective tissue disorders Degenerative, and autoimmune connective tissue disorders Consultation

* * * *

PRACTICE (2 hrs/week) Problem oriented evaluation of the symptoms of patients with esophageal disorders, functional evaluation of patients with esophageal disorders (esophageal manometry, 24 h pH-metry, evaluation of the biliary reflux) Upper gastrointestinal endoscopy. Helicobacter tests Diagnostic work up of patients with CU and Crohn’s disease Symptoms of biliary obstruction, investigative methods for patients with biliary obstruction (symptoms, biochemistry, ultrasonography, ERCP) Problem oriented laboratory investigation of the liver patient Diagnostic work up of patients with acute and chronic pancreatitis Early identification of patients with gastrointestinal cancer. Diagnostic methods General aspects of the patient with endocrine diseases Thyroid diseases in daily clinical practice Practical aspects of dealing with patients with Adrenal diseases Physical examination of patients with rheumatoid diseases

ORAL MEDICINE I. 7th semester

* * * * * * * * * *

LECTURE

PRACTICE

(2 hrs/week)

(1 hr/week)

1. Anatomical and histological structures of the mouth 2. Pathology of the oral mucosa. Primary and secondary skin lesions 3. Patient examination: anamnesis, clinical and other examination 4. Developmental and genetic disorders 5. Physical, chemical and iatrogenic diseases 6. Bacterial diseases 7. Viral diseases 8. Fungal diseases 9. Diseases of the lip 10. Diseases of the tongue

Patient topics. Patient topics. Patient topics. Patient topics. Patient topics. Patient topics. Patient topics. Patient topics. Patient topics. Patient topics.

presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’ presentations according to the lectures’

214 * *

Patient presentations according to the lectures’ topics. Patient presentations according to the lectures’ topics. Patient presentations according to the lectures’ topics.

11. Written exam 12. Immune-based diseases. Allergic diseases

*

13. Mucocutaneous diseases. Granulomatous mucocutaneous diseases

*

14. Consultation

ORAL MEDICINE II. 8th semester LECTURE * * * * * * * * * * * * * *

PRACTICE

(1 hr/week)

(2 hrs/week)

1. Oral Symptoms of the Neuroendocrine System and the Diseases of Metabolism 2. Oral Symptoms of the Gastrointestinal, Hepatic, Cardiovascular and Urogenital System

Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures Patient presentations the lectures

3. Diseases of the Salivary Glands 4. Oral Symptoms of the Blood and Blood-Forming Tissues 5. Oral Symptoms of the Psychological and Psychiatric Diseases 6. Benign Tumors of the Oral Cavity 7. Tumorlike Lesions of the Oral Cavity 8. Premalignant Lesions of the Mouth 9. Differential Diagnosis of the White-Lesions and Ulcers of the Oral Cavity 10. Written Exam 11. Malignant Epithelial and Salivary Tumors of the Oral Cavity 12. Other Tumors of the Oral Cavity (Lymphomas, Sarcomas) 13. Therapy of the Tumors of the Oral Cavity

according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of according to the topics of

14. Consultation

OPERATIVE DENTISTRY I. 7th semester LECTURE

PRACTICE

(1 hr/week)

(6 hrs/week)

*

1. Etiology of caries, the role of dental plaque

*

2. Epidemiology, risk factors, indices. The role of prevention. Digestion, fluoride.

On the first practice the 4th year student has to get familiar with the office equipment. On the second practice two patients will be called, the student has to take their status and history, after that one of them will be treated on the same appointment. The data and the status of the other patient will be recorded in a notebook and the patient will be informed that he/she will be called for another appointment. On the first practice the 5th year student will treat his/her patient from the previous year or summer practice. If there’s no such a patient the student will get someone from the notebook to treat. If there’s a patient a student wants to treat, he/she has to inform the assistants of the department at least two weeks before that


*

3. Etiology of caries, the role of diet, age, gender and habit 4. Response of the pulp to the progress of caries

* 5. Treatment planning * 6. The methods of shade selection *

* * * *

7. The steps of making a posterior composite filling. (Centripetal technique, Z-technique, elastic cavity wall theory, bulk fill systems) 8. Occlusion and articulation in operative dentistry 9. The making of III. IV. Class fillings and incisal fillings. 10. Filling, veneer, inlay, partial crown, full crown. Indications and possibilities 11. Inlay

*

12. WRITTEN DEMONSTRATION

*

13. The cementation of indirect adhesive restorations

*

14. Consultation

215 practice. The students can get extra patients from the notebook or from previously agreed patient examination at the admission office. Giving appointment, administration and any changing is the students’ responsibility. Only the points gained during the semester are considered. Points predetermined on the beginning of the semester define practical grades. By the end of the 4th year at least one from all Black cavity types should be performed, but VI.cl. By the end of the 5th year it’s recommended to perform at least one of all the items from the previously mentioned list. Exceptions

can be: core build up, fiber reinforced post, VI.cl., veneers. The lack of these treatments can be neglected if the student’s points are around the minimal point line (but achieved it). Only the main practice leader can give permission for this, after consulting the practice leaders.

216

OPERATIVE DENTISTRY SEMINAR I. 7th semester Aims: To help the students to increase their theoretical knowledge. The students will have a chance to get answers to their practical and theoretical questions. During the practices and lectures in most of the cases there’s not enough time for discussion and evaluation of special cases. 1. Introduction 2. Development of caries 3. Caries classification 4. Black classification and cavity preparation 5. Cavity nomenclature 6. Minimal and non-invasive preparation 7. Materials used for direct restaurations 8. Amalgam filling 9. Composite filling 10. Matrix systems 11. Occlusion, articulation 12. Finishing and polishing 13. Test 14. Consultation OPERATIVE DENTISTRY II. 8th semester

*

LECTURE

PRACTICE

(1 hr/week)

(5 hrs/week)

1. The Perio-Endo frontier. The comparison of apical and marginal periodontitis. Contact between the pulpal space and the periodontium. Perio-Endo lesions

On the first practice two patients will be called, the student has to take their status and history, after that one of them will be treated on the same appointment. The data and the status of the other patient will be recorded in a notebook and the patient will be informed that he/she will be called for another appointment. On the first practice the 5th year student will treat his/her patient from the previous year or summer practice. If there’s no such a patient the student will get someone from the notebook to treat. If a student wants to treat his/her own patient, he/she has to inform the assistants of the department at least two weeks before that practice. The students can get extra patients from the notebook or from previously agreed patient examination at the admission office. Giving appointment, administration and any changing is the students’ responsibility. By the end of the 4th year at least one from all Black cavity types should be performed, but VI.cl. By the end of the 5th year it’s recommended to perform at least one of all the items from the previously mentioned list. Exceptions can be: core build up, fiber reinforced post, VI. cl., veneers. The lack of these treatments can be neglected if the student’s points are around the minimal point line (but achieved it). Only the main practice leader can give permission for this, after consulting the practice leaders.

* 2. Focal infection *

3. Dental trauma. Diagnostics and treatment.

*

4. Apexification and avulsion

*

5. Endodontic treatment in high risk patients. Local and general effects of different endodontic materials.

* 6. WRITTEN DEMONSTRATION


7. Pain after treatment. Evaluation and solutions.

*

8. Magnification in endodontics

* * * *

9. Endodontic surgery I. – classic methods 10. Endodontic surgery II. - microsurgery 11. Bleaching of root canal treated teeth 12. Reconstruction of rootcanal treated teeth. Principles. Indications. Adhesive posts.

*

8. WRITTEN DEMONSTRATION

*

8. Consultation

217

OPERATIVE DENTISTRY SEMINAR II. 8th semester 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14.

Introduction Pulpal considerations Macro- and microscopy of the endodontium Pulpal and periapical diseases RCT - indications and contraindication RCT- instruments Length measurement RCT – materials RCT – techniques RCF – materials RCF – techniques Retreatment RCT - Coronal restauration Test

PROSTHODONTICS I. 7th semester LECTURE

PRACTICE, SURGERY

PRACTICE, LABORATORY

(1 hr/week)

(4 hrs/week)

(3 hrs/week)

1. Dental instruments used in prosthetic dentistry, practice of impression making in the dental surgery 2. Medical and dental history of the patients, extraoral and intraoral examination, making diagnostic impression and cast

1. Practice of tooth preparation

*

1. Administration, health insurance system in Hungary

*

2. Prosthetic treatment planning. Examination of a partially edentulous patient

*

*

*

3. The clinical anatomy of edentulous mouth: basic definitions. Consequences of total edentulousness, state of edentulousness. 4. The clinical anatomy of the edentulous maxilla (edentulous ridge, hard and soft palate, soft palate, maxillary tuberosity, buccal space). The definition and parts of complete denture. The supportive factors of functional stability of the complete denture. 5. The clinical anatomy of the edentulous mandible I. (alveolar ridge, retromolar pad, retromylohyoid space)

3. Planning of fixed dental prosthesis from the cast of patients

2. Preparing 13,16 abutments with chamfer

3. Making precision and antagonist impressions

4. Making precision and antagonist impressions 4. Tooth preparation for abutment, construction of temporary crown

5. Tooth preparation for abutment, construction of temporary crown

5. Making section cast

218 *

*

*

6. The clinical anatomy of the edentulous mandible II. (sublingual region, buccal shelf, region of buccinator and masseter muscles). The perioral muscles. 7. The fabrication of complete dentures I. (anatomical impression and model and definitive impression and model) 8. The fabrication of complete dentures II.(assesment of the occlusal plane, the occlusal vertical dimension and the centric relation)

*

9. The fabrication of complete dentures III.(Setting up of artificial teeth and try-in)

*

10. The fabrication of complete dentures IV. (Processing of denture in the dental laboratory, reocclusion)

*

11. WRITTEN ASSESMENT

*

12. Prosthetic rehabilitation of cancer patients

* *

13. The fabrication of complete dentures V. (insertion of denture, reocclusion, remontage, relining the denture) 14. Consultation

6. Tooth preparation for abutment, construction of temporary crown 7. Tooth preparation for abutment, construction of temporary crown 8. Making impressions

6. Making section cast

7. Modellation wax patterns of a faced metal bridge 8. Modellation wax patterns of a faced metal bridge

9. Visiting the dental laboratory to watch investing and casting technique 10. Finishing, polishing the 10. Checking the metal framework in the mouth, color framework matching 11. Checking the fixed 11. Fabrication a post and core prosthesis in the mouth, luting with interim cement 12. Making individual trays, definitive impressions and 12. Definitive cementation master models for lower and upper complete dentures 13. Making wax rims and bite 13. Checking the fix registration for complete prosthesis denture 14. Evaluation 14. Evaluation

9. Making impressions and bite registration


219

PROSTHODONTICS II. 8th semester

LECTURE (1 hr/week) *

1. Therapy of partial edentoulism

*

2. Parts of removable partial denture (RPD) – base plate, saddle

*

3. Parts of RPD – cast clasps

* * *

*

*

*

PRACTICE, Surgery (4 hrs/week)

(3 hrs/week)

1. 1st patient: Medical and dental history of the patients, extraoral and intraoral examination, making anatomical (primary) impression and cast 2. Planning and drawing the borders of complete removable denture

1. Making individual trays, definitive impressions and master models for lower and upper complete dentures 2. Making wax rims and bite registration

3. Making functional impression

3. Mountig the casts in an articulator 4. Setting up of artificial teeth

4. Registration of the occlusal plane, the occlusal vertical dimension and the centric relation 5. Removable partial denture – 5. Trying-in the set-up complete dentures theoretical bases in the mouth 6. Fabrication of clasp retained 6. Delivering the total removable dentures RPD 7. Parts of RPD – precision 7. Review session, remontage, if needed attachments MTO – this week in another time 8. 2nd patient: Medical and dental history 8. Fabrication of RPD with of the patients, extraoral and intaoral precision attachment examination, making anatomical (primary) impression and cast 9. Planning and drawing the borders of 9. Fabrication of RPD with complete removable denture telescopic crowns 10. Making functional impression 4. Parts of RPD – type of clasps

*

10. Hybrid prosthesis, theoretical bases

*

11. Fabrication of hybrid prosthesis

*

12. MTO (WRITTEN ASSESSMENT)

*

13. Interim and immediate dentures 14. RPD design for different cases

PRACTICE, Laboratory

11. Registration of occlusal plane, the occlusal vertical dimension and the centric relation 12. Trying-in complete dentures in the mouth 13. Delivering the complete dentures

14. Recall

5. Setting up of artificial teeth 6. Setting up of artificial teeth, MTO 7. Trying-in procedure

8. Preparing dentures for delivery

9. Finishing and polishing the dentures. 10. Finishing and polishing the dentures. Reocclusion. Practising the planning RPD on study cast and on designing sheets. Bending a wire clasp. 11. Planning of partial removable dentures, surveying the models 12. Making denture design for partial denture with metal framework 13. Making denture design for partial denture with metal framework 14. Evaluation of semester

220

DENTAL DIAGNOSTICS AND TREATMENT PLANNING 8th semester

* * * *

*

* *

* * * * * *

LECTURE

PRACTICE

(1 hr/week)

(1 hr/week)

1. Case history, diagnosis in dentistry. Documentation

1. Case history, diagnosis in dentistry. Documentation

2. Decision making in dental therapy

2. Decision making in dental therapy

3. Diagnosis and therapy in oral surgery

3. Diagnosis and therapy in oral surgery

4. Diagnosis and therapy in conservative dentistry. Diagnosis and therapy in endodontics. 5. Diagnosis, treatment planning and therapy in stomato-oncology. Saliva diagnostic methods 6. Diagnosis and classification of TMD Case presentations 7. Diagnosis and therapy in prosthetic dentistry Case presentations 8. Diagnosis and therapy in pediatric dentistry and orthodontics

4. Diagnosis and therapy in conservative dentistry. Diagnosis and therapy in endodontics. 5. Diagnosis, treatment planning and therapy in stomatooncology. Saliva diagnostic methods 6. Diagnosis and classification of TMD Case presentations 7. Diagnosis and therapy in prosthetic dentistry Case presentations 8. Diagnosis and therapy in pediatric dentistry and orthodontics

9. Diagnosis and therapy in parodontology.

9. Diagnosis and therapy in parodontology.

10. Diagnosis and therapy of tooth wear. Diagnostic of tooth discoloration. 11. MTO (WRITTEN ASSESMENT) 12. Photodocumentation. Phonetics in dentistry. 13. Methodology of a scientific research and documenting results. Preparation of thesis.

10. Diagnosis and therapy of tooth wear. Diagnostic of tooth discoloration. 11. MTO (WRITTEN ASSESMENT) 12. Photodocumentation. Phonetics in dentistry. 13. Methodology of a scientific research and documenting results. Preparation of thesis.

PEDIATRIC DENTISTRY I. 8th semester

* * * * * * * * * * * * * *

LECTURE

PRACTICE

(1 hr/week)

(2 hrs/week)

1. Fundamentals of pediatric dentistry 2. Patient management

1. Oral assessment; screening 2. Case history, case report 3. Sealants and preventive resin restorations 4. Restorative procedures for primary teeth 5. Restorative procedures for primary teeth 6. Minimal Invasive Technic 7. Pulp therapy; pulpotomy, pulpectomy 8. Diagnostic methods 9. MTO I. 10. Protective crown (permanent incisor) (model) 11. Stainless steel crown 12. Management of the fractured permanent incisors 13. Consultation 14. MTO II.

3. Morphology of primary teeth 4. Materials in pediatric dentistry 5. Eruption and shedding of teeth 6. Cariology of primary teeth 7. Pulp lesions in primary teeth 8. Cariology of permanent teeth 9. Treatment of permanent teeth 10. Local anesthesia, pharmacology; General anesthesia and pain control for the children 11. Traumatic dental injuries in childhood 12. Radiology in pediatric dentistry 13. Prevention in pediatric dentistry


221

PERIODONTOLOGY I. 7th semester LECTURE

PRACTICE

(1 hr/week)

(2 hrs/week)

*

1. The topics of the Periodontology. Introduction to periodontal diseases 2. Biochemistry and physiology of the connective tissue 3. Biochemistry and physiology of the bone

*

4. Dental plaque and calculus

*

5. Microbiology of periodontal diseases

*

6. Immune responses in periodontal diseases

6. Phantom course: treatment positions

*

7. Mechanisms of destruction of the periodontal tissues

7. Written and practical examination

*

8. The epidemiology of periodontal diseases

*

9. The risk factors of periodontal diseases

*

10. Endocrine disorders as a systemic modifiers of periodontal diseases

*

11. Genetics and periodontal diseases

*

12. Tobacco use and its relation to periodontal diseases

*

13. Systemic effects of periodontal diseases

* *

1. Seminar: Power driven instruments 2. Seminar: Hand instruments 3. Phantom course: practicing the use of scalers 4. Phantom course: practicing the use of universal curettes

5. Phantom course: practicing the use of Gracey curettes

8. Seminar and phantom course: General guidelines for periodontal surgery: instruments, local anesthesia, periodontal dressing, suturing 9. Phantom course: General guidelines for periodontal surgery: instruments, local anesthesia, periodontal dressing, suturing 10. Seminar: periodontal splinting. Phantom course: practicing of intra- and extracoronal periodontal splinting 11. Seminar: Examination of patient with periodontal diseases. Motivation and oral hygiene instruction. Self-performed plaque control. Initial (cause-related) therapy 12. Examination and treatment of patient with gingivitis 13. Examination and treatment of patient with gingivitis

PERIODONTOLOGY II. 8th semester

* *

* * *

*

Lecture (1 hr/week) 1. Classification and symptoms of periodontal diseases 2. Gingival diseases. Enlargement of gingiva. Gingivitis modified by endocrin factors. Gingival diseases modified by hematologic disorders. Gingival diseases modified by medications 3. Gingival diseases modified by other systemic conditions 4. The periodontal abscess. Necrotizing gingivitis. 5. Non-plaque induced inflammatory gingival lesions 6. The chronic periodontitis 7. The aggressive periodontitis 8. Periodontitis modified by systemic conditions 9. Basic principles of periodontal treatment 10. Treatment planing of chronic and aggressive periodontitis 11. Non-surgical periodontal therapy. Full mouth therapy. 12. The use of drugs in periodontal therapy

Practice (2 hrs/week) Practice in surgery: examination, instrumentation, cause-related therapy of patient with gingivitis. Complete therapy of 3 patients suffered from gingivitis.

222 13. The use of antiseptics in periodontal therapy BASIC TREATMENT IN DENTAL MEDICINE (summer practice) 8th semester 4th year dental students have to perform a practice of four weeks (4x35 hours) in Basic Treatment in Dental Medicine. Requirements for accepting the summer practice: - attendance of practices - completing the tasks given by the instructor - pieces upper or lower total removable denture or 1 piece of partial removable denture or 1 piece of post and core with crown or 1 piece of short bridge The summer practice is a criterium topic! Each student must fulfill it. SURGICAL CONSIDERATIONS IN DENTISTRY 7th semester

* * * * * * * * * * * * * *

PRACTICE (2 hrs/week) Internal medicine questions in dental practice Antibiotics in dentistry and oral surgery Cardiac risk patients in dental practice Dental treatment of patients with bleeding disorders Dental treatment of patients following radio/chemotherapy Maxillary sinus diseases and their management Forensic odontology Differential diagnosis of neck masses Differential diagnosis of facial pain Head and neck skin tumors Odontogenic tumors Bisphosphonate induced osteonecrosis of the jaws Sedoanelgesia Written exam

HUNGARIAN LANGUAGE VII. 7th semester Week 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15.

Topics Examination of patient with endodontic problems Root canal treatment Prosthodontics Prosthetical appliances Methods of tooth preparation Procedure of dental impressions Written test Autumn break Types of crowns Types of prostheses Types of bridges Inlays Veneer crowns Written test Oral assessment

Practice/ Skills Revision Reading comprehension Vocabulary practice Word building Lexical drills Dialogue

Reading practice Lexical drill Vocabulary practice Dialogue Role-play


223

HUNGARIAN LANGUAGE VIII. 8th semester Week 1. 2. 3. 4. 5. 6. 7. 8. 9 10. 11. 12. 13. 14. 15.

Topics Fixed bridges Removable partial dentures Complete dentures Dental implants Orthodontic appliances Orthodontics for children Written test Spring break Dental care in pregnancy Dental care in diabetes Xerostomia and Halitosis Prevention of cross infections Cosmetic dentistry Revision for the written test Revision for the oral examination

Practice/ Skills Revision Reading comprehension Word building Lexical drill Dialogue Case study

Dialogue Dialogue Reading comprehension Case study Reading comprehension

DERMATOLOGY 7th semester LECTURE PRACTICE (1 hrs/week) (3 hrs/week) Skin and mucous membrane anatomy and physiology Presentation of skin diseases Types of skin lesions Skin immunology Allergic skin reactions Urticaria Allergic skin diseases Eczema Drug allergy Autoimmune skin diseases Diseases of the connective tissue Vasculitis Vesiculobullous autoimmune skin diseases Viral, bacterial and fungal diseases of the skin and mucous membrane Sexually transmitted diseases Dermatoses caused by parasites Immunodermatologic disorders and papulo-squamous diseases Atopic dermatitis Psoriasis Lichen ruber planus Pityriasis rosea Disorders of the vessels Varicosity Thrombophlebitis Deep vein thrombosis Postthrombotic syndrome Leg ulcer Disorders caused by physical agents Artefact, combustio, congelatio Seborrhoeic dermatoses Acne Rosacea Perioral dermatitis Alopecias Skin tumours Benign lesions

224 Praecancerous lesions Cancers, melanoma malignum Tumours of mesodermal origine Consultation PRACTICE MANAGEMENT IN DENTISTRY 9th semester LECTURE (2 hrs/week) * 1. Career with dental certificate * 2. Quality control in dental practice * 3. HR in dental practice * 4. Service area competitor analysis * 5. Praxis marketing elements * 6. Branding and identity * 7. Connection between medical ethics and right * 8. Equipment in dental surgery. Design and function in dental office * 9. Problems of dental practice building and leading * 10. The difficulties of the foundation of dental practice * 11. Tariff of charges in dental office 12. Taxation of charges in dental office 13. Consultation, written demonstation DISEASES OF TEMPOROMANDIBULAR SYSTEM 9th semester LECTURE (1 hr/week) * 1. Pathology of temporomandibular system 2. Anatomy, normal function of temporomandibular joint * and muscles, innervations * 3. Inflammatory and degenerative thicknesses * 4. Symptoms of TMJ dysfunction * 5. Etiology of TMJ dysfunction 6. Clinical examination methods, diagnostics 7. Imaging methods, importance of MRI * 8. Differential diagnostics * 9. Conservative therapy I.: Medicaments * 10. Conservative therapy II.: Splints * 11. Conservative therapy III.: Physio- and Physicotherapy. 12. Conservative therapy IV.: Psychodiagnostic and psychotherapy 13. Correction of occlusion, prosthetic treatment of TMJ * patients. WRITTEN ASSESSMENT *

SEMINAR (1 hr/week)

The practical knowledge of the topics, patient examination methods, students get skill in taking case history and examination of the patients. Introduction of the preparation of splints, students make and insert a splint themselves.


225

DENTAL IMPLANTOLOGY I. 9th semester

* *

* * * * * *

Lecture (2 hrs/week) 1. Osseointegration, bone-physiology, bone-healing 2. History of dental implantology. Types, design of dental implants. The definition of an implant system 3. Prosthetic aspects of implant planning 4. X-ray diagnoses in implantology, CT, 3D etc. 5. Procedure of implant surgery 6. Consultation before implant surgery: indications and contraindications. Anatomical consideration of the jaws. Surgical planning 7. Bone augmentation procedures and different methods 8. Implant surgery combined with sinus elevation, bone augmentation 9. The dental office and the personnel requirements of dental implantology. Legal aspect of implantology, written consent 10. Immediate loading 11. Loss of implants, recall, overview 12. Implantology in orthodontics 13. Exam

DENTAL IMPLANTOLOGY II. 10th semester

* * * * * * * * * * * * *

Practice (2 hrs/week) 1. The DenTi Implant system in implantology practice I. 2. The DenTi Implant system in implantology practice II. 3. The Straumann Implant system in implantology practice 4. The SGS Implant system in implantology practice 5. The CAMLOG Implant system in implantology practice 6. The Nobel Biocare Implant system in implantology practice I. 7. The Nobel Biocare Implant system in implantology practice II. 8. The Ankylos Implant system in implantology practice I. 9. The Ankylos Implant system in implantology practice II. 10. Spring Congress 11. The MDI Implant system in implantology practice 12. Written exam, Evaluation of course 13. Semester overwiev

OPERATIVE DENTISTRY III. 9th semester Practice (4 hrs/week) Requirements and evaluation of operative dentistry practice Patient management: On the first practice the 4th year student has to get familiar with the office equipment. On the second practice two patients will be called, the student has to take their status and history, after that one of them will be treated on the same appointment. The data and the status of the other patient will be recorded in a notebook and the patient will be informed that he/she will be called for another appointment. On the first practice the 5th year student will treat his/her patient from the previous year or summer practice. If there’s no such a patient the student will get someone from the notebook to treat. If there’s a patient a student wants to treat, he/she has to inform the assistants of the department at least two weeks before that practice. The students can get extra patients from the notebook or from previously agreed patient examination at the admission office. Giving appointment, administration and any changing is the students’ responsibility. Only the points gained during the semester are considered. Points predetermined on the beginning of the semester define practical grades. Not fulfilling the following conditions results in automatical failure of the semester: By the end of the 4th year at least one from all Black cavity types should be performed, but VI.cl.

226 By the end of the 5th year it’s recommended to perform at least one of all the items from the previously mentioned list. Exceptions can be: core build up, fiber reinforced post, VI.cl., veneers. The lack of these treatments can be neglected if the student’s points are around the minimal point line (but achieved it). Only the main practice leader can give permission for this, after consulting the practice leaders.

OPERATIVE DENTISTRY Seminar III. 9th semester Seminar (1 hr/week) Current topics of operative dentistry according to contemporary scientific literature OPERATIVE DENTISTRY IV. 10th semester (6 hrs/week) PRACTICE Requirements and evaluation of operative dentistry practice Patient management: On the first practice two patients will be called, the student has to take their status and history, after that one of them will be treated on the same appointment. The data and the status of the other patient will be recorded in a notebook and the patient will be informed that he/she will be called for another appointment. On the first practice the 5th year student will treat his/her patient from the previous year or summer practice. If there’s no such a patient the student will get someone from the notebook to treat. If there’s a patient a student wants to treat, he/she has to inform the assistants of the department at least two weeks before that practice. The students can get extra patients from the notebook or from previously agreed patient examination at the admission office. Giving appointment, administration and any changing is the students’ responsibility. Only the points gained during the semester are considered. Points predetermined on the beginning of the semester define practical grades. Not fulfilling the following conditions results in automatical failure of the semester: By the end of the 4th year at least one from all Black cavity types should be performed, but VI.cl. By the end of the 5th year it’s recommended to perform at least one of all the items from the previously mentioned list. Exceptions can be: core build up, fiber reinforced post, VI.cl., veneers. The lack of these treatments can be neglected if the student’s points are around the minimal point line (but achieved it). Only the main practice leader can give permission for this, after consulting the practice leaders. OPERATIVE DENTISTRY Seminar IV. 10th semester Seminar (1 hr/week) Case studies. Comprehensive treatment planning and diagnostics DENTAL IMPLANTOLOGY (in Prosthodontics) 10th semester

* * * * * * * * * *

LECTURE (2 hrs/week) 1. Surface properties and modifications of dental implants. Characteristics of titanium 2. Hands on practice on manikin 3. The components of an implant system. Theoretical background of implantology: osseointegration, soft tissue integration, loading 4. Implant-prosthetic treatment planning: alternative treatment plans. Team work, documentation. Special fields: young, old patients, smoking etc. 5. Implant planning with CT and guide systems 6. Types of implant supported prostheses, indication, conditions 1. Temporary prosthesis 7. Types of implant supported prostheses, indication, conditions 2. Occlusion, articulation. Abutments 8. Dental technical aspects of implantology. Laboratory steps of preparing fixed prosthesis 9. Dental technical aspects of implantology. Laboratory steps of preparing removable prosthesis 10. Implant retained hybrid prosthesis

Curriculum 2014/2015 * * * *

227 11. Maintenance, oral hygiene, recall. Prosthetic problems and their solution. Possible complications during implant surgery, prevention and therapy. 12. Interesting and special implant prosthetic cases 13. Written test 14. Case presentations, course evaluation

ORTHODONTICS I. 9th semester Lecture (1 hr/week) * * * * * * * * * * * * *

1. History of Orthodontics 2. Classification and Terminology of Dentofacial Problems 3. Malocclusions and Functional Disorders 4. Clinical Orthodontic Diagnosis, Functional Analysis 5. Orthodontic Study Cast Analysis 6. Radiographic Analysis for Orthodontic Diagnosis 7. Treatment Plan and Documentation of Orthodontic Treatment 8. Removable Plate-Appliances 9. Functional Appliances 10. Fixed Appliances 11. Extraoral Appliances and Auxiliary Appliances used in Orthodontics 12. Anchorage in Orthodontics 13. Orthodontic Treatment Mechanics of the 21st Century 14. Consultation

Practice (2 hrs/week) 1. Clinical Examination: Anamnestic Records, Written Orthodontic Documentation 2. Clinical Examination: Intraoral and Functional Examination 3. Orthodontic Impression, Preparation of the Study Cast 4. Orthodontic Impression, Preparation of the Study Cast 5. Orthodontic Impression, Preparation of the Study Cast 6. Measurements on the Orthodontic Study Casts 7. Orthodontic photo documentation 8. MTO I. 9. Cephalometric Analysis of the Lateral Radiograph 10. Cephalometric Analysis of the Lateral Radiograph 11. Cephalometric Analysis of the Frontal Radiograph 12. Cephalometric Analysis of the Frontal Radiograph and Orthopantomogram 13. Cephalometric Analysis of the Frontal Radiograph and Orthopantomogram 14. MTO II.

ORTHODONTICS II. 10th semester

* * * * * * * * * * *

Lecture (1 hr/week) 1. Biology, Types and Mechanics of Orthodontic Tooth Movement 2. Interceptive Orthodontics, Early Treatments 3. Characteristics of Orthodontic Treatment During Mixed Dentition Period and Pubertal Growth 4. Conservatve Dentofacial Orthopedic Treatments in Late Childhood and Puberty 5. Adult Orthodontics 6. The Role of Orthodontics in Interdisciplinary Therapy 7. Dentoalveolar Surgical Interventions Associated to Orthodontic Treatments 8. Preparation and Planning of Orthognatic Surgical Interventions 9. Combined Ortho-Surgical Treatments 10. Comprehensive Treatment of Craniofacial Malformations 11. Modalities and Appliances of the Retention

Practice (2hrs/week) 1. Seminar: Removable Orthodontic Appliances 2. Clinical Presentation of Removable Orthodontic Appliances 3. Clinical Presentation of Removable Orthodontic Appliances 4. Clinical Presentation of Removable Orthodontic Appliances 5. Seminar: Fixed Orthodontic Appliances 6. Clinical Presentation of Fixed Orthodontic Appliances 7. Clinical Presentation of Fixed Orthodontic Appliances 8. Clinical Presentation of Fixed Orthodontic Appliances 9. Seminar: Braking of Bad Habits 10. Braking of of Bad Habits 11. Seminar: Complex Care of Children with Cleft Lip and Palate

228 * *

12. Causes of the Orthodontic Treatment

Relapse,

Complications

13. Dental and Hygienic Cae of Patients Wearing Orthodontic Appliances 14. Consultation

of

12. Complex Care of Children with Cleft Lip and Palate in Practice 13. Hygienic Coaching, Motivation and Professional Cleaning of Patients Who Wear Fixed Orthodontic Appliance 14. Consultation

ORAL SURGERY III. 9th semester

* * * * * * * * * * * * * *

Lecture (2 hrs/week) 1. Principles of trauma management. Conservative treatment of facial trauma. Mandibular fractures 2. Trauma: Midface, frontal skull base fractures 3. Temporomandibular joint surgery 4. Orthognathic surgery 5. Preprosthetic surgery 6. Distraction osteogenesis of the facial skeleton 7. Salivary gland diseases 8. Bisphosphonate related osteonecrosis of the jaws 9. Cleft lip and palate surgery 10. Etiology and diagnosis of oral cancer 11. Scientific search engines and databases 12. Surgical management of oral cancer. Reconstruction 13. Written exam 14. Discussion

Practice (4 hrs/week)

Minimal practice requirement: - 10 simple tooth extractions - 3 operation: Apicectomy Tooth extraction by operation Extraction of impacted or displaced tooth Incision (drainage) of abscess Cystectomy

ORAL SURGERY IV. 10th semester Practice (6 hrs/week) Practice in basic dentoalveolar surgery: - apicectomy - excochleation - incision - bone correction Minimal requirements of semester 8 simple tooth extraction, 2 operations PEDIATRIC DENTISTRY II. 9th semester

* * * * * * * * * * * * * *

Lecture (1 hr/week) 1. Diagnostic methods, oral assessment; screening 2. Bad habits in childhood 3. Caries therapy for primary teeth 4. Oral diseases and parodontology in childhood 5. Secondary diseases of caries in permanent dentition 6. Minimal invasive therapy 7. Pulp therapy for permanent teeth 8. Dental surgery in pediatric dentistry 9. Prosthetic dentistry in childhood 10. MTO 11. Traumatic injuries of primary teeth 12. Traumatic injuries of permanent teeth 13. Assessment of semester 14. Consultation

Practice (4 hrs/week) Diagnostic methods Caries prevention in childhood The caries lesion and its management in children and adolescents Pedodontic endodontics


229

PEDIATRIC DENTISTRY III. 10th semester

*

Practice (3 hrs/week) Diagnostic methods Caries prevention in child dental care The caries lesion and its management in children and adolescents Pulp therapy Knowledge of the materials and their usage

PERIODONTOLOGY III. 9th semester

* * * * * * * * * * * * *

Lecture (1 hr/week, ie. 2 hours/fortnight) 1. Aim, indications and contraindications of periodontal surgery 2. Aim and indication of periodontal plastic surgery 3. Elimination of periodontal pocket: gingivectomy and gingivoplasty. Treatment of enlargement of gingiva 4. Periodontal surgery: access therapy 5. Periodontal wound healing: regeneration or reparation 6. GTR. Flap preparation and suturing in regenerative surgical procedures 7. Grafting procedures 8. Biomediators in regenerative procedures 9. Pedicle soft tissue graft in root coverage procedures 10. Free soft tissue graft in root coverage procedures 11. Gingival augmentation, crown-lengthening procedures, the deformed edentulous ridge 12. Electrosurgery and lasers in periodontal surgical procedures 13. Postsurgical care. Outcome of surgical periodontal therapy


Examination and treatment of patient with gingivitis or chronic periodontitis.

PERIODONTOLOGY IV. 10th semester

* * * * * * * * * * * * *

Lecture (1 hr/week) 1. Supportive periodontal therapy 2. Treatment of furcation-involved teeth 3. Endodontics and periodontics. Treatment of dentin hypersensitivity 4. Occlusal therapy 5. Prosthetic rehabilitation of periodontitis patients. Periodontal health and restorative procedures 6. Orthodontics and periodontal therapy 7. Outcomes of periodontal therapy 8. The use of drugs in periodontal therapy 9. The use of antiseptics in periodontal therapy 10. Peri-implant mucositis and peri-implantitis 11. Treatment of risky patients I 12. Treatment of risky patients II 13. HIV-associated periodontal conditions 14. Consultation


Treatment of patient with chronic or aggressive periodontitis.

230 PREVENTIVE DENTISTRY 9th semester

* * * * * * * * *

Lecture (1 hr/week) 1. Definitions and objectives of preventive dentistry 2. Definitions of dental caries and role of fluorides 3. The effects of diet for general health and for dental caries 4. Preventive measures in periodontology 5. Preventive strategy and the orthodontic therapy 6. Preventive measures in prosthodontics 7. Iatrogen infections in dentistry and their prevention 8. Aethiology of oral precancerous lesions and their prevention 9. Exam – giving possibilities to get suggested mark for the examination

Practice (1 hr/week)

Visiting a medical department ward to maintain dental preventive instruction and motivation for inn-patients

PROSTHODONTICS III. 9th semester

* * * * * * * * * * * * * *

Practice (6 hrs/week) 1. Medical and dental history of the patients, extraoral and intraoral examination, making diagnostic impression and cast 2. Medical and dental history of the patients, extraoral and intraoral examination, making diagnostic impression and cast, jaw registration 3. Planning of fixed/removable dental prosthesis 4. Tooth preparation for abutments, construction of temporary crown 5. Tooth preparation for abutments, construction of temporary crown 6. Tooth preparation for abutments, construction of temporary crown 7. Tooth preparation for abutments, construction of temporary crown 8. Precision/master impressions and jaw registration 9. Precision/master impressions and jaw registration 10. Try in of fixed part & metal framework in the mouth, shade selection 11. Trial insertion of waxed-up dentures 12. Insertion of completed denture 13. Review 14. Review

PROSTHODONTICS SEMINAR I. 9th semester

* * * * * * * * * * * * * *

Practice (1 hrs/week) 1. Patient case presentation and treatment planning, alternatives 2. Patient case presentation and treatment planning, alternatives 3 Patient case presentation and treatment planning, alternatives 4. Treatment planning and prosthetic treatment of edentoulism in children 5. Different types of major connectors 6. Patient case presentation and treatment planning, alternatives 7. Patient case presentation and treatment planning, alternatives 8. Patient case presentation and treatment planning, alternatives 9. Patient case presentation and treatment planning, alternatives 10. Patient case presentation and treatment planning, alternatives 11. Patient case presentation and treatment planning, alternatives 12. Patient case presentation and treatment planning, alternatives 13. Patient case presentation and treatment planning, alternatives 14. Evaluation


231

PROSTHODONTICS IV. 10th semester Practice (6 hrs/week) 1. Medical and dental history of the patients, extraoral and intraoral examination, making diagnostic impression and cast 2. Medical and dental history of the patients, extraoral and intraoral examination, making diagnostic impression and cast, jaw registration 3. Planning of fixed/removable dental prosthesis 4. Tooth preparation for abutments, construction of temporary crown 5. Tooth preparation for abutments, construction of temporary crown 6. Tooth preparation for abutments, construction of temporary crown 7. Tooth preparation for abutments, construction of temporary crown 8. Precision/master impressions and jaw registration 9. Precision/master impressions and jaw registration 10. Try in fixed part & metal framework in the mouth, shade selection 11. Trial insertion of waxed-up dentures 12. Insertion of completed denture 13. Check up 14. Review

* * * * * * * * * * * * * *

TREATMENT OF TRAUMATIC DENTAL INJURIES IN CHILDHOOD 10th semester

* * * * * * * * * * * * * *

Lecture, Seminar (Lecture: 2 hrs/week, Seminar: 1 hr/week) 1. Traumatic injuries in childhood 2. Orofacial trauma in childhood 3. Injuries to the primary dentition 4. Crown and root fractures in the permanent teeth 5. Concussion, subluxation and luxation. Intrusion, Avulsion. 6. Injuries to developing teeth, Endodontic management 7. Treatment with implants in the trauma situation 8. Radiographic findings 9. Soft tissue injuries; injuries to the supporting bone 10. Orthodontic Management of the Traumatized Dentition 11. Prevention of dental and oral injuries 12. Follow-up procedures and recall schedule following the various trauma types 13. Consultation 14. MTO

FORENSIC MEDICINE 9th semester LECTURE week (2 hrs/ every second week) 1 Introduction. Essential law. 2 Medical law – Duties of the doctor 3 Medical malpractice in dentistry 4 Time of death. Changes after death. 5 Autopsy 6 Classification of wounds I. (blunt force and sharp injuries) 7 Classification of wounds II. ( heat and cold injuries, shot wounds) 8 Trauma of the head, face and denture Mid-term assessment 9 10 Medical documentation, documentation of injuries – expert opinion in dental cases 11 Autopsy 12 Accidents (traffic, sport, household) 13 Forensic aspects of alcohol and drug abuse 14 Identification of the living and of the dead 15 DNA investigations in forensic medicine

232

Faculty of Pharmacy


GENERAL INFORMATION REGARDING THE CREDIT SYSTEM AT THE FACULTY OF PHARMACY I. STRUCTURE OF STUDIES Students have to acquire 300 credits in order to obtain the Doctor of Pharmacy degree. Credits have to be acquired according to the following scheme: Compulsory subjects: 240 credits Compulsory elective subjects: 44 credits - Subjects of the ninth semester: one has to acquire min. 12 credits - Students have to submit a thesis in the tenth semester (10 credits) - 6 months of compulsory pharmacy practice, including 1 month of hospital practice (22 credits) Elective subjects: 16 credits Students have to obtain min. 80 credits until the end of the fourth semester.

233

234

Lecturer

2

-

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


Course Requirement

Exam

2

-

Exam

2

-

Exam

3

-

Term Mark

2

-

Term Mark

2

-

Exam

3

-

Term Mark

3

-

Exam

3

-

Exam

2

-

Term Mark

0

-

Term Mark

2

-

Term Mark

2

-

PHARMACY 2014/2015 1st year fall, 1st semester Compulsory Subjects

GYTKKA071

Pharmaceutical Biology

Dr. GÁBOR LACZKÓ associate professor Dr. LAJOS SIMON associate professor Dr. JÁNOS KARSAI associate professor Dr. JÓZSEF ELLER senior research associate Dr. FERENC PETÁK associate professor Dr. ÁRPÁD SZŐCS associate professor Dr. OTTÓ BERKESI associate professor, Dr. TAMÁS Department of Physical Chemistry KÖRTVÉLYESI associate professor and Materials Science Dr. habil. MÁRTA SZÉLL Head of Department Dr. habil. ZSUZSANNA LÁSZLÓ associate professor Medical Genetics Department

GYTKKA111

Anatomy I.

Anatomy Department

GYTKKA491

English Language I.

GYTKKA041

Physics-Biophysics I.

GYTKKA011

History of Pharmacy

GYTKKA021

Mathematics

GYTKKA022

Mathematics

GYTKKA031

Informatics

GYTKKA051

GYTKKA052

General Chemistry

General Chemistry

GYTKKA981

Latin Language

GYTKKA551

Hungarian Language I. Elective Subjects *

Experimental Physics Department Phramaceutical Chemistry Department Faculty of Science and Informatics, Bolyai Institute Faculty of Science and Informatics, Bolyai Institute Dept. of Med. Physics and Informatics Department of Physical Chemistry and Materials Science

Prof. habil. ANDRÁS MIHÁLY professor, Head of Department Dr. ÉVA DEMETER language Department of Foreign Languages teacher, Head of Department Dr. ÉVA DEMETER language Department of Foreign Languages teacher, Head of Department Dr. ÉVA DEMETER language Department of Foreign Languages teacher, Head of Department

2

-

2

-

-

2

-

2

2

-

-

4

3

-

2

-

-

2

-

2

-

4

Curriculum 2014/2015 XT0011-PHE

Criteria Subjects Physical Education*

235 Sport Center


* One has to complete 2 semesters of Physical Education until the end of the 5th year.

-

2

Signature

0

-

236

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

PHARMACY Course Requirement

Exam

3


Term Mark

2


Exam

4

General Chemistry exam

Exam

3

Term Mark

4

General Chemistry exam, practice General Chemistry exam, practice

Evaluation

2

Exam

2

Exam

2

Mathematics

Signature

0

Mathematics

Signature

0

-

Term Mark

2

-

Term Mark

0

English Language I.

Term Mark

2

Hungarian Lang. I.

2014/2015 1st year spring, 2nd semester Compulsory Subjects Physics-Biophysics II.

GYTKKA042 GYTKKA043 GYTKKA061 GYTKKA091

GYTKKA092

GYTKKA101 GYTKKA113 GYTKKA541 GYTKKA542 GYTKKA531 GYTKKA532 GYTKKA492 GYTKKA552

Dr. GÁBOR LACZKÓ associate Experimental Physics Department professor Physics-Biophysics II. Dr. GÁBOR LACZKÓ associate Experimental Physics Department professor Inorganic Chemistry Prof. habil. GYÖRGY DOMBI Institute of Pharmaceutical professor, Head of Department Analysis Qualitative Chemical Analysis Dr. TAMÁS MARTINEK associate Pharmaceutical Chemistry professor Department Qualitative Chemical Analysis Dr. LÓRÁND KISS assistant professor, Dr. ISTVÁN MÁNDITY Pharmaceutical Chemistry resident Department Quantitative Chemical Analysis I. Inorganic and Analitical Chemistry Dr. PÉTER ANTAL professor, Dept. Dr. GÁBOR GALBÁCS associate prof., Dr. PÁL SIPOS ass. prof. Anatomy II. Prof. habil. ANDRÁS MIHÁLY professor, Head of Department Anatomy Department Biostatistics Dr. KRISZTINA BODA associate Dept. of Med. Physics and professor Informatics Biostatistics Dr. KRISZTINA BODA associate Dept. of Med. Physics and professor Informatics First Aid and Resuscitation Dr. ANDREA CSERJÉS head physician National Ambulance Service First Aid and Resuscitation Dr. ANDREA CSERJÉS head physician National Ambulance Service English Language II. Dr. ÉVA DEMETER language Department of Foreign Languages teacher, Head of Department Hungarian Language II. Dr. ÉVA DEMETER language Department of Foreign Languages teacher, Head of Department Elective Subjects * Criteria Subjects

2

-

-

3

3

-

2

-

-

5

2

-

2

-

1

-

-

1

1

-

-

1

-

2

-

4

General Chemistry exam, practice Anatomy I. exam

Curriculum 2014/2015 XT00112PHE

Physical Education*

237 Sport Center



-

2

S

0

-

238

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


CE

4

Quant. Chem. Anal. I.

Term Mark

4


Evaluation

1


Exam

4

Term Mark

5

Exam

4

General Chem., Qual. Chem. Analysis General Chem., Qual. Chem. Analysis Anatomy II. exam

Term Mark

2

Anatomy II. exam

Exam

2

Term Mark

1

Exam

3

Term Mark

0

Math. (exam, pract.), General Chem. (exam, pract.) Math. (exam, pract.), General Chem. (exam, pract.) Math. (exam), Gen. Chem. (exam, pr.), Quant. Chem.(pr.), Phys.Biophys. Hung. Lang. II.

2014/2015 2nd year fall, 3rd semester Compulsory Subjects

GYTKKA103

GYTKKA104 GYTKKA105

Quantitative Chemical Analysis II. Quantitative Chemical Analysis II. Quantitative Chemical Analysis Calculation

GYTKKA121

Organic Chemistry I.

GYTKKA122

Organic Chemistry I.

GYTKKA151

Physiology I.

GYTKKA152

Physiology I.

GYTKKA131

Inorganic and Analitical Chemistry Dr. PÉTER ANTAL professor, Dr. GÁBOR GALBÁCS associate Dept. professor, Dr. PÁL SIPOS associate professor Inorganic and Analitical Chemistry Dr. ÉVA ENYEDY research Dept. worker, NOÉMI JAKAB assistant research worker Inorganic and Analitical Chemistry Dr. GÁBOR GALBÁCS associate Dept. professor Institute of Pharmaceutical Prof. habil. FERENC FÜLÖP Chemistry professor, Head of Department Institute of Pharmaceutical Dr. LORAND KISS senior lecturer Chemistry Physiology Department Prof. habil. GYÖNGYI HORVÁTH professor Physiology Department Dr. BALÁZS BODOSI assistant professor Department of Physical Chemistry Dr. GÁBOR PEINTLER associate and Materials Science professor

Physical Chemistry I.

2

-

-

6

1

-

4

-

-

6

4

-

-

2

2

-

Department of Physical Chemistry Dr. GÁBOR PEINTLER associate and Materials Science professor GYTKKA132

Physical Chemistry Calculation

-

1

Department of Physical Chemistry Dr. ZOLTÁN KIRÁLY associate and Materials Science professor GYTKKA161 GYTKKA553

Colloid Chemistry Hungarian Language III. Elective Subjects

Department of Foreign Languages Dr. ÉVA DEMETER language teacher, Head of Department

2

-

-

4

Curriculum 2014/2015 XT0011-PHE

Criteria Subjects Physical Education*

239 Sport Center



1

S

0

-

240

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

PHARMACY

Term Mark

4

CE

5

Phys. Chem. I. exam, Calculation, Colloid Chemistry exam Organic Chem. I. exam

Exam

5

-

Term Mark

2

-

CE

6

Signature

0

Exam

4

Physiology I. (exam, practice) Physiology I. (exam, practice) Organic Chemistry I. Organic Chemistry II. (parallel) Physiology I. (exam, pract.)

Exam

3

-

Term Mark

0

Hung. Lang. III.

Signature

0

Course Requirement

2014/2015 2nd year spring, 4th semester Compulsory Subjects

GYTKKA133 GYTKKA123

Physical and Colloid Chemistry practice Organic Chemistry II.

Department of Physical Chemistry Dr. GÁBOR PEINTLER associate and Materials Science professor Institute of Pharmaceutical Chemistry

GYTKKA142

Pharmaceutical Botany

Pharmacognosy Department

GYTKKA143

Pharmaceutical Botany

Pharmacognosy Department

GYTKKA153

Physiology II.

Physiology Department

GYTKKA154

Physiology II.

Physiology Department

GYTKKA171

Biochemistry

GYTKKA591

Pharmaceutical Propedeutics

GYTKKA554

Hungarian Language IV. Elective Subjects

Prof. FERENC FÜLÖP professor, Head of Department Dr. ZSUZSANNA HAJDÚ associate professor Dr. ZSUZSANNA HAJDÚ associate professor Prof. habil. GYÖNGYI HORVÁTH professor Dr. BALÁZS BODOSI assistant professor Prof. habil.LÁSZLÓ DUX professor, Head of Department

Biochemistry Department Pharmaceutical Technology Department

ifj. Dr. GÉZA REGDON associate professor Dr. ÉVA DEMETER language Department of Foreign Languages teacher, Head of Department

-

5

3

-

3

-

-

2

4

-

-

2

4

-

2

-

-

4

-

total 35

-

1

Criteria Subjects GYTKKA511 XT00112PHE

Dr. ERZSÉBET CSÁNYI associate professor

Summer Practice After 2nd Year Physical Education*

Sport Center



Signature

0

-


241

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

PHARMACY

Exam

3

Term Mark

3

Exam

5

Term Mark

5

Signature

0

Exam

4

Term Mark

0

Exam

3

Signature

0

Term Mark

0

Signature

0

Course Requirement

2014/2015 3rd year fall, 5th semester Compulsory Subjects Pharmacognosy Department GYTKKA181


Prof. habil. IMRE MÁTHÉ professor emeritus Dr. ATTILA HUNYADI assistant lecturer Prof. habil. FERENC FÜLÖP professor, Head of Department


Dr. ZSOLT SZAKONYI associate professor

Pharmaceutical Technology Department Microbiology Department

Prof. habil. PIROSKA RÉVÉSZ professor, Head of Department Prof. habil. YVETTE MÁNDI professor, Head of Department

Microbiology Department

Prof. habil. YVETTE MÁNDI professor, Head of Department

Pathophysiology Department

Prof. habil. GYULA SZABÓ professor, Head of Department

Pathophysiology Department

Prof. habil. GYULA SZABÓ professor, Head of Department

Pharmacognosy I. Pharmacognosy Department

GYTKKA182

GYTKKA231

GYTKKA232 GYTKKA221

GYTKKA201

GYTKKA202

GYTKKA191

GYTKKA192 GYTKKA555

XT0011-PHE

Pharmacognosy I.

Pharmaceutical Chemistry I.

Microbiology and Immunology

-

4

6

2

-

-

Pathophysiology I.

2

Pathophysiology I.

Department of Foreign Languages Dr. ÉVA DEMETER language teacher, Head of Department

Sport Center


-

-

4

Microbiology and Immunology

Hungarian Language V. Elective Subjects Criteria Subjects Physical Education*

-

4

Pharmaceutical Chemistry I. Pharmaceutical Technology I.

3

-

2

-

2

-

3

-

1

Organic Chem. II. exam, Botany II. (exam, pract.) Organic Chem. II. exam, Botany II. (exam, pract.) Qual.Chem., Quant.Chem.II., Organic Chem. II. Qual.Chem., Quant.Chem.II., Organic Chem. II. Phys. Chem. I., II., Colloid Chem. Biol.exam, Anat.II., Phys. II. exam, pr., Biochemistry Biology exam, Anatomy II., Physiology II. exam, Biochemistry Anatomy II. exam, Physiology II. exam, pr., Biochem. exam Anatomy II. exam, Physiology II. exam, pr., Biochem. exam Hung. Lang. IV.

242

Lecturer

2

-

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


CE

3

Pharmacognosy I. exam

Term Mark

3

CE

5

Term Mark

5

Exam

3

Pharmacognosy I. exam, practice Qual.Chem., Quant.Chem.II., Organic Chem. II. Qual.Chem., Quant.Chem.II., Organic Chem. II. Pharm. Techn. I.

Term Mark

3

Pharm. Techn. I.

Term Mark

3

Pharm. Techn. I.

Exam

4

Signature

0

Pathophys. I., Immunology Pathophys. I. (exam, pr.)

Exam

2

Mathematics, Physiology II. exam, Biochemistry

Term Mark

2

Term Mark

0

Mathematics, Physiology II., Biochemistry Hung. Lang. V.

2014/2015 3rd year spring, 6th semester Compulsory Subjects Pharmacognosy Department GYTKKA183


Prof. habil. IMRE MÁTHÉ professor emeritus Dr. ATTILA HUNYADI assistant lecturer Prof. habil. FERENC FÜLÖP professor, Head of Department


Dr. ZSOLT SZAKONYI associate professor

Pharmaceutical Technology Department Pharmaceutical Technology Department Pharmaceutical Technology Department

Prof. habil. PIROSKA RÉVÉSZ professor, Head of Department Dr. ERZSÉBET CSÁNYI associate professor Dr. ERZSÉBET CSÁNYI associate professor

Pharmacognosy II. Pharmacognosy Department

GYTKKA184

GYTKKA233

GYTKKA234 GYTKKA222 GYTKKA223

GYTKKA224

Pharmacognosy II.

Pharmaceutical Chemistry II.

4

Pharmaceutical Chemistry II. Pharmaceutical Technology II. Pharmaceutical Technology Prescription Pharmacy I. Pharmaceutical Technology Galenic Prep. and Their Manufacture

-

-

-

6

2

-

-

3

-

3

2

-

-

2

Pathophysiology Department GYTKKA193

Pathophysiology II.

GYTKKA194

Pathophysiology II.


Biopharmacy Biopharmacy Hungarian Language VI. Elective Subjects Criteria Subjects

Prof. habil. GYULA SZABÓ professor, Head of Department Pathophysiology Department Prof. habil. GYULA SZABÓ professor, Head of Department Department of Pharmacodynamics Dr. ISTVÁN ZUPKÓ associate and Biopharmacy professor, Head of Department Dr. ÁRPÁD MÁRKI assistant professor

4

Department of Pharmacodynamics Dr. ÁRPÁD MÁRKI assistant and Biopharmacy professor Department of Foreign Languages Dr. ÉVA DEMETER language teacher, Head of Department

2

-

-

3

-

3

Curriculum 2014/2015 GYTKKA512 XT00112PHE

243 Dr. ERZSÉBET CSÁNYI associate professor

Summer Practice After 3rd Year Physical Education*

Sport Center



-

total 35

-

1

Signature

0

Signature

0

244

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


2014/2015 4th year fall, 7th semester GYTKKA261

Compulsory Subjects Pharmaceutical Analysis

GYTKKA262

Pharmaceutical Analysis

GYTKKA225

Pharmaceutical Technology III.

GYTKKA226

Pharmaceutical Technology Prescription Pharmacy II. Pharmaceutical Technology Sterile and Aseptic Drug Formulations Pharmacodynamics I.

GYTKKA227

GYTKKA251 GYTKKA252

Pharmacodynamics I.

GYTKKA271

Public Health and Preventive Medicine

GYTKKA281

Ethics in Pharmacy

GYTKKA291

Introduction to Law

GYTKKA301

Introduction to Economics

GYTKKA557

Hungarian Language VII.

Institute of Pharmaceutical Analysis Institute of Pharmaceutical Analysis Pharmaceutical Technology Department Pharmaceutical Technology Department Pharmaceutical Technology Department

Prof. habil. GYÖRGY DOMBI professor, Head of Department Dr. GERDA SZAKONYI assistant professor Prof. habil. PIROSKA RÉVÉSZ professor, Head of Department Dr. ERZSÉBET CSÁNYI associate professor Dr. ZOLTÁN AIGNER associate professor

Department of Pharmacodynamics and Biopharmacy Department of Pharmacodynamics and Biopharmacy Department of Public Health

Dr. ISTVÁN ZUPKÓ associate professor, Head of Department Dr. RENÁTA MINORICS assistant professor Dr. habil. EDIT PAULIK associate professor, Head of Department

3

-

-

5

2

-

-

3

-

3

3

-

-

2 Dr. habil. ILDIKÓ CSÓKA associate professor, Head of Institute Institute of Drug Regulatory Dr. habil. ILDIKÓ CSÓKA Affairs associate professor, Head of Institute Institute of Drug Regulatory Dr. habil. ILDIKÓ CSÓKA Affairs associate professor, Head of Institute Department of Foreign Languages Dr. ÉVA DEMETER language teacher, Head of Department

2

3

Term Mark

4

Signature

0

Term Mark

5

Term Mark

3

Exam

3

Term Mark

2

Exam

1

Exam

2

Pathophys. II., Biopharmacy (th., pr.) Pathophys. II., Biopharmacy (th., pr.) Physiology II. (th., pr.), Pathophys. II., Microbiology, Immunology Pharm. Techn. II.

Exam

2

Pharm. Techn. II.

Exam

2

Pharm. Techn. II.

Term Mark

0

Hung. Lang. VI.

3

-

Institute of Drug Regulatory Affairs

2

Exam

Pharm. Chem. II. (theory, practice) Pharm. Chem. II. (theory, practice) Pharm. Techn. II. Pharm. Techn. II., Prescr. Pharm. I. Pharm. Techn. II.

-

-

2

-

-

2

Curriculum 2014/2015 GYTKKA1211

245

Preparation of Diplomawork I.

-

total10

-

1

Signature

0

Signature

0

Elective Subject

Criteria Subjects XT0011-PHE

Physical Education*

Sport Center



-

246

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


CE

6

Pharm. Techn. III.

Term Mark

2

Term Mark

2

Pharm. Techn. III., Prescr. Pharm. II. Pharm. Techn. III.

Term Mark

3

Pharm. Techn. III.

Exam

3

Pharmacodynamics I. (th., pr.)

Term Mark

2

CE

6

Pharmacodynamics I. (th., pr.) Ethics in Pharm.;Intro. to Law, Economy

Exam

2

Signature

0

Term Mark

2

CE

0

Physiology II., Pathophys. II., Pharmacodynamics Physiology II., Pathophys. II., Clin. Lab. (th.) Intro. to Law, Intro. to Economy Hung. Lang. VII.

Signature

0

Thesis Consultation I.

2014/2015 4th year spring, 8th semester GYTKKA228 GYTKKA229

Compulsory Subjects Pharmaceutical Technology IV.

GYTKKA253

Pharmaceutical Technology Prescription Pharmacy III. Pharmaceutical Technology Industrial Preparation and Investigation of Solid Dosage Forms (Tablet and T. Coating) Pharmaceutical Technology Investigation of Dosage Forms Pharmacodynamics II.

GYTKKA254

Pharmacodynamics II.

GYTKKA595

GYTKKA596

GYTKKA311

Drug Regulatory Affairs

GYTKKA481

Clinical Laboratory Practice

GYTKKA482 GYTKKA991 GYTKKA558 GYTKKA1221

Clinical Laboratory Practice Pharmacy Administration Hungarian Language VIII.

Pharmaceutical Technology Department Pharmaceutical Technology Department Pharmaceutical Technology Department

Prof. habil. PIROSKA RÉVÉSZ professor, Head of Department Dr. JÁNOS BAJDIK assistant lecturer ifj. Dr. PÉTER KÁSA assistant professor

Pharmaceutical Technology Department Department of Pharmacodynamics and Biopharmacy

Prof. habil. PIROSKA RÉVÉSZ Professor, Head of Department Prof. habil. GYÖRGY FALKAY professor, Dr. RÓBERT GÁSPÁR senior lecturer Dr. JUDIT HAJAGOS-TÓTH assistant lecturer Dr. habil. ILDIKÓ CSÓKA associate professor, Head of Institute Prof. habil. GYÖRGY FALKAY professor Dr. ANNA KLUKOVITS assistant professor Dr. PÉTER DORÓ associate professor, Head of Department Dr. ÉVA DEMETER language teacher, Head of Department

2

-

-

3

-

Department of Pharmacodynamics and Biopharmacy Institute of Drug Regulatory Affairs Department of Pharmacodynamics and Biopharmacy Department of Pharmacodynamics and Biopharmacy Institute of Clinical Pharmacy Department of Foreign Languages

-

4

3

-

-

3

3

-

2

-

-

2

-

1

-

2 total 10

Preparation of Diplomawork II. Elective Subjects Criteria Subjects

5

Curriculum 2014/2015 XT00112PHE

Physical Education*

247 Sport Center



-

1

Signature

0

248

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory

PHARMACY

Exam

4

Exam

3

CE

5

Term Mark

2

Term Mark

2

Exam

2

Course Requirement

2014/2015 5th year, 9th semester Compulsory Subjects Basic Clinical Disciplines GYTKKA331

Clinical Pharmacy GYTKKA341

Pharmacodynamics III. GYTKKA255

Pharmacodynamics III. GYTKKA256

Pharmaceutical Care

2nd Department of Internal Medicine Department of Clinical Pharmacy

Dr. NOÉMI GRUBER associate professor Dr. PÉTER DORÓ associate professor, Head of Department Department of Pharmacodynamics Prof. habil. GYÖRGY FALKAY and Biopharmacy professor, Dr. RÓBERT GÁSPÁR senior lecturer Department of Pharmacodynamics Dr. ANNA KLUKOVITS assistant and Biopharmacy professor Department of Clinical Pharmacy Dr. PÉTER DORÓ associate professor, Head of Department

-

2

-

3

-

-

3

-

GYTKKA351

Natural Treatments

2 Pharmacy Practice 1. (2 months)


Preparation of Diplomawork III. -

GTYKKA471

Compulsory Elective Subjects Ward Pharmacy (Clinical Pharmacy II) Pharmaceutical Psychology

Department of Clinical Pharmacy Dept. Of Behavioural Sciences

Dr. PÉTER DORÓ associate professor, Head of Department Dr. CSABA HAMVAI intern

GYTKKA321 GYTKKA421

2

2

GYTKKA451

Veterinary Pharmacy Quality Assurance

3

Department of Pharmacodynamics Dr. RÓBERT GÁSPÁR associate and Biopharmacy professor


3

Department of Pharmacodynamics Dr. ESZTER DUCZA assistant and Biopharmacy professor Institute of Drug Regulatory Prof. TAMÁS PAÁL professor

2 3

40 Term Mark hrs total Signature 10

6 0

Pharmacodyn. II. (th., pr.) Pathophys. II., Biopharm.,Public Health II. Phys.-Biophys. II., Pharmacognosy II., Pathophys. II., Pharmacodyn. II. Completion of the 4th year subjects Thesis Consultation II.

Exam

2

Exam

2

Exam

2

Pathophys. II.Biopharm., Pharmacodyn. II. Physiology II., Pathophys. II., par: Pharmacodyn. III. Pharmacodynamics II.

Exam

3

Pharm. Techn. IV.

-

-

Phys. II., Pathophys. II., Pharmacodyn. II. Pathophys. II., Biopharm., Public Health II. Pharmacodyn. II. (th., pr.)

Curriculum 2014/2015 Phythotherapy

249 Affairs Institute of Pharmacognosy

Everyday Dermatology

Department of Clinical Pharmacy

Computerized Dosage Form Planning Criteria Subjects Physical Education*

Pharmaceutical Technology Department

Dr. DEZSİ CSUPOR assistant lecturer Dr. PÉTER DORÓ associate professor, Head of Department ifj. Dr. GÉZA REGDON associate professor

Sport Center


GYTKKA461 GYTKKA571 GYTKKA361 XT0011-PHE

2 2

Exam

2

Exam

2

Term Mark

2

Signature

0

Pharmacognosy II. exam

-

-

2

-

1

-

250

Lecturer

Credit

Department

Form of exam

Course

Hrs/week: Practice

Course Code

Hrs/week: Theory


2014/2015 5th year, 10th semester Compulsory Subjects GYTKKA522


Pharmacy Practice 2. (4 months)

40 hrs

Thesis *One has to complete 2 semesters of Physical Education until the end of the 5th year. GYTKKA391

Term Mark 16 Defence

10

Evaluation

2

-

Evaluation

2

-

Evaluation

2

-

Evaluation

2

Short History of Hungary I.

Evaluation

2

Evaluation

2

Evaluation

2

-

Evaluation

2

-

Evaluation

2

-

Evaluation

2

Physiology II., Organic Chemistry II.

Elective Subjects in the years 1-4 GYTKKA901 GYTKKA1041

General Laws in Chemistry Short History of Hungary I. Radiochemistry

GYTKKA891

Institute of Pharmaceutical Analysis Dept. of Behavioural Sciences Institute of Pharmaceutical Analysis

Short History of Hungary II. GYTKKA1042 GYTKKA 671

Practical Optical Spectroscopy

Basic Communication The Role of Nutrition in the Prevention and Treatment of GYTKKA1081 Diseases

Dept. of Behavioural Sciences Institute of Pharmaceutical Analysis Institute of Drug Regulatory Affairs

GYTKKA1051

Communication in Pharm. Practice GYTKKA840 The Harms of Smoking and GYTKKA1071 Strategies to Quit GYTKKA780

Computer Literature

Institute of Pharmacodynamics and Biopharmacy

Prof. habil. GYÖRGY DOMBI professor, Head of Department SERFİZİNÉ Dr. ADÉL TÓTH assistant professor Prof. habil. GYÖRGY DOMBI professor, Head of Department SERFİZİNÉ Dr. ADÉL TÓTH assistant professor Prof. habil. GYÖRGY DOMBI professor, Head of Department Dr. habil. ILDIKÓ CSÓKA associate professor, Head of Institute Dr. RÓBERT GÁSPÁR associate professor

2 2

-

2

-

2

-

2

-

2

2 Institute of Drug Regulatory Affairs Institute of Pharmacodynamincs and Biopharmacy Institute of Pharmaceutical Chemistry

Dr. habil. ILDIKÓ CSÓKA associate professor, Head of Institute Dr. RÓBERT GÁSPÁR associate professor Dr. ZSOLT SZAKONYI associate professor

-

-

-

-

2

-

2

-

-

1


Psychiatry Department

Illicite Drug Use

Psychiatry Department

Biopharmaceuticals

GYTKKA1190

Clinical Aspects of Tropical Diseases Basic Clinical Pharmacology

GYTKKA701

Bio-Inorganic Chemistry

Institute of Pharmaceutical Analysis Psychiatry Department Psychiatry Department Institute of Pharmaceutical Analysis

Prof. habil. GÁBOR BÁLINT professor Prof. habil. GÁBOR BÁLINT professor Dr. GERDA SZAKONYI assistant professor Prof. habil. GÁBOR BÁLINT professor Prof. habil. GÁBOR BÁLINT professor Prof. habil. GYÖRGY DOMBI professor, Head of Department

Hrs/week: Practice

Lecturer

2

-

2

-

2

-

2

-

2

-

2

-

Credit

Tropical Medicine

GYTKKA1180

GYTKKA511

Department

Form of exam

GYTKKA441 GYTKKA1031

Course

Hrs/week: Theory

Course Code

251

Exam

2

Exam

2

Physiology II., Pathophys. II., Biopharm. -

Evaluation

2

Biology, Biochemistry

Evaluation

2

-

Evaluation

2

-

Evaluation

2

-

Course Requirement

252 Recommended textbooks for first year pharmacy students It is recommended to purchase the latest edition of the following textbooks! PHYSICS-BIOPHYSICS Recommended: • Péter Makra: Physics-biophysics (handout, see http://www.noise.physx.u-szeged.hu/MP/Education/PhysicsBiophysics/, also available on CooSpace) • Péter Makra (ed): Physics-biophysics practicals (handout, see http://www.noise.physx.u-szeged.hu/MP/Education/PhysicsBiophysics/, also available on CooSpace) • Damjanovich Sándor - Fidy Judit - Szöllısi János: Medical biophysics (3rd edition). Medicina Könyvkiadó Rt • Serway R A, Jewett J W. Physics for scientists and engineers. Thomson Brooks/Cole • G.B. Arfken et al: University Physics, Academic Press, Inc. • Tarján ed. An introduction to Biophysics with medical orientation, Budapest: Akadémiai Kiadó • Á. Süli: Physics for students of pharmacy (handout) • P. Simon: Practical Physics (handout) HISTORY OF PHARMACY • Lajos Simon: History of Pharmacy (handout) MATHEMATICS MATHEMATICS (available on: www.model.u-szeged.hu/Education-courses/mathematics for pharmacy students) • Janos Karsai: Basic Math for Life Sciences (interactive presentations) • Janos Karsai: Interactive lecture presentations for Mathematics in Pharmacy • Janos Karsai: Exercises and problems in Mathematics (handout) • Janos Karsai et al: Exercises for the Mathematics practical for Pharmacy students (handout) • Krisztina Boda and Janos Karsai: Mathematics Problems, Exercises for Pharmacy students (handout) • Tibor Asztalos: Mathematics for 1st year Pharmacy students (handout) • • • •

Krisztina Boda and János Karsai: Mathematics Problems, Exercises for Pharmacy students (handout) Tibor Asztalos: Mathematics for 1st year Pharmacy students (handout) János Karsai: Exercises and problems in Mathematics (handout) János Karsai et al: Exercises for the Mathematics practical for Pharmacy students (handout) www.model.u-szeged.hu/Education-courses/mathematics for pharmacy students or http://www.model.u-szeged.hu/user/karsai/math/mathgytk/math-english.html

GENERAL CHEMISTRY • Árpád Szőcs: General Chemistry (handout, PDF) • Árpád Szőcs: Calculations in General Chemistry (handout, PDF) • Árpád Szőcs: Practices in General Chemistry (handout, PDF) PHARMACEUTICAL BIOLOGY • Cell Biology and Molecular Genetics I. • Cell Biology and Molecular Genetics II. • Life (textbook) ANATOMY • András Mihály, MD, DSc: Human Anatomy, Histology and Development, Handout for Pharmacy Students at University of Szeged INORGANIC CHEMISTRY • N.N. Greenwood and A. Eranshaw: Chemistry of the Elements, 1st ed., Pergamon Press Ltd. QUALITATIVE CHEMICAL ANALYSIS • Vogel’s Qualitative Inorganic Analysis, 7th ed. Longman QUANTITATIVE CHEMICAL ANALYSIS Theory Obligatory: • D. A. Skoog, D. M. West, F. J. Holler and S. R. Crouch: Fundamentals of Analytical Chemistry, Brooks/Cole


253

Recommended: • D. A. Skoog, F. J. Holler and T. A. Nieman: Principles of Instrumental Analysis, Saunders College Publishing • Daniel C. Harris, Quantitative chemical analysis, 7th edition • Kellner, Mermet, Otto, Widmer: Analytical chemistry, Wiley-VCH • H. H. Willard et al.: Instrumental Methods of Analysis, Wadsworth Publ. Co. • J. S. Fritz and G. H. Schenk: Quantitative Analytical Chemistry, Allin and Bacon Practice Obligatory: • G. Galbács, K. Gajda-Srantz: Laboratory Manual for Pharmacy Students in Quantitative Analytical Chemistry (manual in manuscript form, currently available for the students in handout form) • Csikkel-Szolnoki, K. Jáky: Problems in Quantitative Analytical Chemistry for Pharmacy Students (ed. By G. Ács) Szeged, JATE Press BIOSTATISTICS • Lecture notes: http://www.szote.u-szeged.hu/dmi/ • Arnold Naiman, Robert Rosenfeld, Gene Zirkel: Understanding Statistics. McGraw-Hill International Editions • M.J.Campbell, D.Machin: Medical Statistics. John Wiley & Sons • Station A Glantz: Primer of Biostatistics. McGraw-Hill Recommended: • Arnold Naiman, Robert Rosenfeld, Gene Zirkel: Understanding Statistics. McGraw-Hill International Editions • Station A Glantz: Primer of Biostatistics. McGraw-Hill • M.J.Campbell, D.Machin: Medical Statistics. John Wiley & Sons • Rice Virtual Lab in Statistics. http://onlinestatbook.com/rvls.html FIRST AID AND RESUSCITATION • Brent, Karren: First Aid for Colleges and Universities, Brady Morton Series SHORT HISTORY OF HUNGARY (elective) • Kiss-Dózsai, András: A History of the Hungarian People. SZOTE, Szeged, 1987 • Lázár, I: Hungary – A Brief History. Corvina, Budapest, 1989 • Lázár, I: An Illustrated History of Hungary, Corvina, Budapest, 1998 • Csorba Cs, Estók J. Karádi: Illustrated History of Hungary, Helikon Kiadó, 2005 GENERAL LAWS IN CHEMISTRY (elective) • Lecture notes (handout) RADIOCHEMISTRY (elective) • Lecture notes (handout) Recommended textbooks for second year pharmacy students It is recommended to purchase the latest edition of the following textbooks! ORGANIC CHEMISTRY • Dr. Árpád Molnár: Basic Organic Chemistry I. and II. (handout) • J. McMurry: Fundamentals of Organic Chemistry, Brooks/Cole Publishing Company • Solomons-Fryhle: Organic Chemistry PHARMACEUTICAL BOTANY • Fahn: Plant Anatomy, Pergamon Press PHYSIOLOGY • William F. Ganong: Review of Medical Physiology from 22nd ed. by The McGraw-Hill Companies, Inc. • Dr. Mária Dux: Physiology Laboratory Manual (handout) PHYSICAL CHEMISTRY • Physical Chemistry (handout), 1987, SZOTE

254 • Physico Chemical Experiments (handout), 1987, SZOTE COLLOID CHEMISTRY Theory Obligatory: • Etelka Tombácz: Colloid Chemistry for Pharmaceutical Students. JatePress, Szeged 1988. • Lecture notes: http://koll1.chem.u-szeged.hu/colloids/staff/zoli/Pharmacy/ Recommended: • D. F. Evans, H. Wennerström: The Colloidal Domain: Where Physics, Chemistry, Biology and Technology Meet. Wiley-VCH , New York 2nd Ed., 1999. • D. H. Everett: Basic Principles of Colloid Science. The Royal Society of Chemistry, London 1988. • D. J. Shaw: Introduction to Colloid and Surface Chemistry, Butterworth-Heinemann, Oxford 4th Ed. 2007 • R. J. Hunter: Foundations of Colloid Science. Vol. 1., Clarendon, Oxford 2001. Laboratory Practice Obligatory: • Etelka Tombácz: Laboratory Manual of Colloid Chemistry for Pharmaceutical Students. JatePress, Szeged 1987. BIOCHEMISTRY • Pamela C. Champe, Richard A. Harvey: Lippincott’s Illustrated Reviews, BIOCHEMISTRY, 4th edition, Wolters Kluwer/Lippincott Williams&Wilkins • Robert K. Murray, Daryl K. Granner, Peter A. Mayes, Vicot W. Rodwell: Harper’s Illustrated Biochemistry, 25th edition Lange (International Edition) BASIC COMMUNICATION (elective course) • Lecture presentations: www.pharm.u-szeged.hu/gyfi/eng PRACTICAL OPTICAL SPECTROSCOPY (elective) • Lecture notes THE ROLE OF NUTRITION IN THE PREVENTION AND TREATMENT OF DISEASES (elective) • Lecture notes Recommended textbooks for third year pharmacy students It is recommended to purchase the latest edition of the following textbooks! PHARMACOGNOSY Obligatory: • Tóth, László: Pharmacognosy I-II • Gellért, Mária: Pharmacognosy Practice Recommended: • Bruneton, Jean: Pharmacognosy Phytochemistry Medicinal Plants, 2nd edition, Lavoisier Publishing, Paris 1999 • Eavens, William Charles: Pharmacognosy, W. B. Saunders, Edinburgh 15th edition 2009 PHARMACEUTICAL CHEMISTRY • Gareth Thomas (University of Porthsmouth) Medicinal Chemistry, 2nd Edition) John Wiley &Sons Ltd • Graham L. Patrick, An Introduction to Medicinal Chemistry, Oxford University Press • Foye’s Principles of Medicinal Chemistry, 6th Edition, Eds.: Williams D. A., Lernke T.L.; Lippincott, Philadelphia PHARMACEUTICAL TECHNOLOGY Obligatory: • M.E. Aulton: Aulton’s Pharmaceutics.The Design and Manufacture of Medicines, Churchill Livingstone Recommended: • M.J. Groves: Parenteral Technology Manual, Interpharm Press • S. Wu-Pong, A.B.C. Yu: Applied Biopharmaceutics & Pharmacokinetics, McGraw-Hill • Infield, I. Edafiogho: Calculations for Pharmaceutical Practice, Churchill Livingstone MICROBIOLOGY • Levinson: Rewiews of Medical Microbiology and Immunology. Lange Med. Publ. 11th, Ed.: 2010, • Practical Notes Edited by R. Pusztai, SZOTE, 2002


IMMUNOLOGY • A.K. Abbas et. al.: Basic Immunology, 2nd ed. (2006-2007), ELSEVIER Saunders PATHOPHYSIOLOGY Texbooks • Gayton and Hall: Texbook of Medical Physiology 12th ed. 2011 ISBN: 978-1-4160-4574-8/978-0-8089-2400-5 • Damjanov: Pathophysiology, Elsevier (Saunders title), 2008, ISBN: 978-1-4160-0229-1 • McPhee, Hammer: Pathophysiology of Disease 6th ed., McGraw-Hill Medical, 2009, ISBN- 0071621679/9780071621670 • Silbernagl, Lang: Color Atlas of Pathophysiology, George Thieme Verlag, 2000, ISBN: 9780865778665/9783131165510 • Kumar, Abbas, Fausto, Aster: Robbins & Cotran Pathologic Basis of Disease, 8th ed, Elsevier (Saunders title) 2010, ISBN: 978-1-4160-3121-5 • Goldman, Schafer: Goldman’s Cecil Medicine, 24th ed., Elsevier (Saunders title), 2012, ISBN: 978-1-4377-2788-3 • Longo, Fauci, Kasper, Hauser, Jameson, Loscalzo: Harrison’s Principles of Internal Medicine, 18th ed., McGraw-Hill Medical, 2012, ISBN 9780071748896/007174889X Handouts (for practice) • Fekete M.: Pathophysiology exercises II. 1987. • Szabó G.: Introduction to Electrocardiography 1999. BIOPHARMACY • Leon Shargel and Andrew Yu: Applied Biopharmaceutics and Pharmacokinetics, Appleton and Lange, 5th edition 2004 • M.E. Burton., L.M. Shaw, J.J. Schentag, W.E. Evans: Applied Pharmacokinetics and Pharmacodynamics. Principles of Drug Monitoring, 4th ed., Lippincott Williams and Wilkins, 2006 COMMUNICATION IN PHARMACY PRACTICE (elective) • W. N. Tindall, R. S. Beardsley, C. L. Kimberlin: Communication Skills in Pharmacy Practice,., Lippincott Williams&Wilkins, 4th Ed. 2007 COMPUTER LITERATURE (elective) • handout provided by the university THE HARMS OF SMOKING AND STRATEGIES TO QUIT (elective) • Lecture notes BIOPHARMACEUTICALS (elective) • Lecture notes

255

256 Recommended textbooks for fourth year pharmacy students It is recommended to purchase the latest edition of the following textbooks! PHARMACEUTICAL ANALYSIS • Kenneth A. Connors: A Textbook of Pharmaceutical Analysis, John Wiley and Sons 3rd ed, 2007 PHARMACODYNAMICS • Bertram G. Katzung: Basic and Clinical Pharmacology, Prentice-Hall International Inc.,11th ed. 2009 PUBLIC HEALTH • Paulik E (ed.): Public Health and Preventive Medicine. Medicina Publishing House, Budapest, 2013 ETHICS IN PHARMACY • Lecture presentations: www.pharm.u-szeged.hu/gyfi/eng INTRODUCTION TO LAW • Lecture presentations: www.pharm.u-szeged.hu/gyfi/eng INTRODUCTION TO ECONOMICS • Lecture presentations: www.pharm.u-szeged.hu/gyfi/eng DRUG REGULATORY AFFAIRS • Lecture presentations: www.pharm.u-szeged.hu/gyfi/eng CLINICAL LABORATORY PRACTICE • William J Mashall, Stephen K Bangert: Clinical chemistry, sixth edition, Elsevier, 2008 PHARMACY ADMINISTRATION • Gordon E. Appelbe, Joy Wingfield: Dale and Appelbe’s Pharmacy Law and Ethics, 9th edition, published by Pharmaceutical Press, 2009 Recommended textbooks for fifth year pharmacy students It is recommended to purchase the latest edition of the following textbooks! CLINICAL PHARMACY Recommended: • Clinical Pharmacy and Therapeutics by Roger Walker and Kate Whittlesea, Published by Churchill Livingstone, 4th edition 2007 • Roger and Clive R.W. Edwards: Clinical Pharmacy and Therapeutics, 3rd edition, Published by Churchill Livingstone, 2003 PHARMACODYNAMICS • Bertram G. Katzung: Basic and Clinical Pharmacology, Prentice-Hall International Inc.,11th ed. 2009 NATURAL TREATMENTS • S. Fulder: The handbook of alternative and complementary medicine, 3rd ed., Oxford Univ. Press, 1996 • Fundamentals of complementary and alternative medicine. Ed. By M.S. Micozzi, Churchill Livingstone 1996 PHARMACEUTICAL PSYCHOLOGY • Beardsley R.S., Kimberlin C.L., Tindall W.N. (2008): Communication skills in Pharmacy Practice: a practical guide for students and practitionres. Wolters Kluwer/Lippincott Williams and Wilkins • Csabai M., Molnár P. (2000): Health, Illness and Care. Springer Orvosi Kiadó Kft. • Nolen_hoeksema S., Fredrickson B.L., Loftus G.R., Wagenaar W.A. (2009): Atkinson and Hilgard’s Introduction to Psychology. Cengage Learning EMEA QUALITY ASSURANCE • Lecture presentations: www.pharm.u-szeged.hu/gyfi/eng PHARMACEUTICAL CARE

Curriculum 2014/2015 •

257

Clive Edwards, Paul Stillman: Minor Illness or Major Disease?, 4th edition, Published by Pharmaceutical Press, 2006

WARD PHARMACY (compulsory elective) • British National Formulary 60 September 2010, Published jointly by BMJ Publishing Group Ltd and Royal Pharmaceutical Society, 2010 • BNF for Children 2010-2011,Published jointly by the British Medical Association, Royal Pharmaceutical Society, the Royal College of Paediatrics and Child Health, and the Neonatal and Paediatric Pharmacists Group, 2010 VETERINARY PHARMACY (compulsory elective) • Steven B Kayne, Michael H Jepson: Veterinary Pharmacy, Pharmaceutical Press 2004 PHYTOTHERAPY(compulsory elective) • F. Capasso, T. S. Gaginella, G. Grandolini, A. A. Izzo: Phytotherapy – A Quick Reference to Herbal Medicine. Springer, 2003 EVERYDAY DERMATOLOGY(compulsory elective) • W.H.C. Burgdorf, G. Plewig, H.H. Wolff, M. Landthaler: Braun-Falco ’s Dermatology, 3rd edition, Published by Springer, 2009 5th year / Spring semester The deadline of submitting the thesis is March 2015 Pharmacy students perform a 4-month clerkship (3 successive months in public pharmacies, 1 month can be accomplished in pharmacy, pharmaceutical factory, galenical laboratory, university department or hospital pharmacy). Fees: From the academic year 2005/2006 fifth year pharmacy students have to pay the whole tuition fee for the second semester of the fifth year.

INTERIM PRACTICE Pharmacy students are required to complete a compulsory practice in a pharmacy which must be accredited by the country concerned. At the completion of the practice an evaluation form should be filled in, signed, stamped and sent directly from the pharmacy or submitted by the student in a sealed envelope. (The form can be downloaded from our website). A “Letter of Acceptance” completed by the pharmacy has to be presented at the Foreign Students’ Secretariat until May 6, 2014.

2nd year pharmacy students must perform a practice of 4 weeks in a pharmacy. 3rd year pharmacy students must perform a practice of 4 weeks in a pharmacy. 4th year pharmacy students must perform a practice of 2 months in a pharmacy (pharmacy, pharmaceutical factory, galenical laboratory, university department or hospital/clinical pharmacy). Note: The precondition of starting the 2-month compulsory practice is completing all the courses of the first four years and acquiring 16 credits of elective subjects.

5th year pharmacy students must perform a 4-month clerkship in the second semester of the academic year. (3 successive months in public pharmacies and 1 month in a hospital/clinical pharmacy.)

258 SYLLABUSES FOR 1ST YEAR PHARMACY STUDENTS PHYSICS-BIOPHYSICS 1st semester LECTURE Flow of fluids. Flow of incompressible fluids: the equation of continuity. Flow of ideal fluids: Bernoulli’s law. Flow of viscous fluids: Newton’s law and the Hagen–Poiseulle law. Laminar and turbulent flow. Intermittent flow in tubes with elastic walls. Non-Newtonian fluids Diffusion. Fick’s first law. Generalised equation of continuity. Fick’s second law. The oxygen supply of tissues Heat transport. Heat conduction. Heat convection. Heat radiation. Newton’s law of cooling. Evaporation. Heat exchange between the human body and its environment Transport through biological membranes. Passive diffusion. Facilitated diffusion; the kinetics of facilitated diffusion: the Michaelis–Menten equation. Active transport Membrane balance of neutral particles: osmosis. Van’t Hoff’s law. The physiological significance of osmosis. The Starling effect. Dialysis Membrane potential. Origin of the membrane potential. Diffusion potential. Determining the membrane potential experimentally. Resting potential. Action potential The experimental basis of quantum mechanics. Laws of thermal radiation. Photoelectric effect. The Franck-Hertz experiment. The spectrum of the hydrogen atom and the Bohr model. Particle-wave duality. Heisenberg’s uncertainty principle. Atomic orbitals 2nd semester LECTURE Optical spectroscopy. The energy-level structure of molecules: Born–Oppenheimer approximation; Jablonski diagram. Luminescence properties: absorption, fluorescence and phosporescence spectra; efficiency, polarisation and life time of radiation. Experimental methods of molecular spectroscopy: atomic absorption, atomic fluorescence, molecular absorption and molecular fluorescence spectroscopy Lasers. Special properties of laser radiation. Physical principles of laser operation: Einstein coefficients and optical gain. Population inversion. Laser oscillators. Laser types. Lasers in medical practice X-rays. General properties of X-rays. X-ray sources. Xray spectra: Bremstrahlung and characteristic radiation. The attenuation of X-rays in a medium. Medical applications of X-rays: the basics of tomography. Determining molecular structure with the help of X-ray diffraction Nuclear radiation. Models of the nucleus. Radioactive decay law, radioactive dating. Types of nucleus decay: alpha decay, beta decay, positron decay, K-electron capture, gamma radiation. Absorption of nuclear radiation in a medium. Dosimetry. Ionising radiation and the human being: effects of radiation, hit theories, radiation protection. Radiation meters: ionisation chambers, the Geiger–Müller counter, scintillators, gamma camera. Nuclear medicine

PRACTICE Statistical evaluation of experimental data Viscometry Electrical conductance. Conductometry Refractometry Optical imaging Optical absorption spectroscopy Kinetics of heating and cooling Chirality optical activity. Polarimetry Recording time-dependent electric signals Electronic amplifiers Absorption of nuclear radiation Optical emission spectroscopy

HISTORY OF PHARMACY * * *

Medicinal treatments and medicines in ancient societies: in prehistoric times, in Mesopotamia, Egypt, India, China, Hellas and in the Roman Empire. The rise of Chistianity. Nestorius and Nestorians. Monasticism. Medieval medicine. Medicine under Islam. The establishment of the first pharmacy.

Curriculum 2014/2015 * * * * * * * * * * * * * * * * * * * *

259 Crusades. The rise of universities (Salerno, Montpellier and other European universities). The first medical decree. Foundation of the first medical faculty. Renaissance. Art and science in the Renaissance. The time of alchemy. The emergence of medicinal chemistry (iatrichemistry), Paracelsus. The formation of the European pharmacy, foundation of pharmacies. The "Age of Scientific Revolution", medicine and pharmacy in the 17th century. Innovations in the 17th century. The story of Cinchona bark. Medicine and pharmacy in the 18th century. Innovation in the 18th century. Medicine and pharmacy in the 19th and 20th centuries. Formation of pharmaceutical industry. The history of medical and pharmaceutical education. History of the Hungarian pharmaceutical education and postgraduate training of pharmacists. Dispensatoriums, Antidotariums. Pharmacopoeias, national and international pharmacopoeias, Ph.Hg.VII. National and international standards of drugs. Definition and classification of drug. Expiry date. Drugs and doses. Dosage forms. The principles of efficacy, safety of drug use. The therapeutic index and the margin of safety. Drug utilization: monitoring of drug consumption. Regulation and control of drug consumption. Tolerance, physical dependence and drug abuse. Naming of medical substances: Latinized and licensed (trade) names. The forms dispensation. Formula Magistralis, Normalis, Originalis, Nosocomialis. The three levels of drug production. Public, clinical and hospital pharmacies. The conditions of a working pharmacy. Administration work in pharmacies. The development of drug control. Drug control and quality assurance (GMP, GLP, GXP). Drug trade and the drug supply in Hungary. Pharmaceutical societies and chambers. International organization of health care. World Health Organization (WHO). International Red Cross (Red Crescent, Red Half-Moon). Commission of Narcotic Drugs. International Pharmaceutical Federation (FIP). International Federation of Pharmaceutical Manufactures Association (IPFMA). European Federation of Pharmaceutical Manufacturers Association (EPFMA).

MATHEMATICS

*

*

*

*

*

*

*

LECTURE Basic concepts: sets, numbers, intervals, relations, functions. Elementary properties of functions: domain, range, graph, even/odd functions, periodicity, boundedness, monotonicity, concavity, maxima and minima. Compositions, one-to-one functions, inverse function. Elementary functions in the life sciences: Arithmetical and geometrical growth, power functions, exponential and logarithmic functions, trigonometric functions. Graphical study of functions and practical processes: elementary and logarithmic transformations, logarithmic plots. Applications of Calculus in life sciences: Intuitive concept of limits; Continuity Instantaneous growth rate, derivative: definition, general and geometrical meaning, equation of the tangent line. Second derivative, acceleration and concavity. Differentiation rules Applications: Relation between the growth and concavity and the derivatives, graphical and numerical study. Find maxima, minima and the maximal growth rate. Investigation processes in Pharmacy. Antiderivative, indefinite integral: inversion of differentiation, understanding vector fields. simple integration methods and rules Definite integral: geometric meaning (area under curve), and formal definition. Elementary properties and rules. The integral mean value. Simple numerical methods of integration. Area function, Newton-Leibniz formula.

PRACTICE Exercises and solutions of problems in the topics of the corresponding lectures.

260 Applications in Pharmacy. *

* *

Functions of two variables: graphical methods, partial derivatives and their geometrical meaning. Local minima and maxima. Curve fitting with the least square method, linear regression. Differential equations in Pharmacy: basic properties, vector fields, initial value problems, equilibria. Autonomous systems. Graphical study. Solution in case of separable right hand sides. Linear equations, exponential decay. Logistic equations. Some external effects and their meaning in life sciences. Equations of drug elimination, dosing, infusion, population dynamics.

INFORMATICS 1st semester PRACTICE (2 hrs/week) * Basic concepts of informatics in life sciences. Terminology used in informatics and computer techniques. The role of the human component. * Local and Network drives; File and folder operations on physical and logical drives. Overview of computer architecture. Hardware and software. Problems with national languages - solutions. * Operating systems. Overview of distributed and real-time operating systems, multitasking. Computer networks: Novell Netware, Internet. Resource management, network communication. * Creating formatted documents; stand-alone and shareble versions. Compatibility problems. PDF files. * Manual and automatic text editing and formatting. The use of templates and styles. * Simple vs. complex documents in life sciences. Tables, charts, ClipArt, WordArt, hypertext. * Elements of desktop publishing. Paper and screen oriented versions. * 1st practical test. * Data types in the pharmacological sciences. Number, date, time, money, dimensions, etc. * Practices on formulae, useful spreadsheet functions in life sciences. * Statistical evaluation and graphical presentation of medical/pharmacological data. * Slide presentation softwares. * 2nd practical test. * Computer aided measurement of bioelectrical signals. Data and image processing. * Seeking medical/pharmacological Web-sites. Fine tuning of Internet browsers. BIOSTATISTICS *

*

Data definition, types of data, displaying data. Characteristics of discrete and continuous distributions. Probability, random variables and their types, distributions. Some important distributions: binomial, Poisson, uniform and normal distribution and their properties. Statistical estimation, confidence intervals. Testing hypotheses, significance. Errors in hypothesis tests. Onesample t-test, paired and Independent samples t-tests. One-way analysis of variance. Relationship between continuous variables, correlation, linear regression. Relationship between categorical variables: contingency tables and 2 test, The 2 test for goodness of fit. Nonparametric methods.

GENERAL CHEMISTRY 1st semester

* *

LECTURE The science of chemistry Chemistry as physical science. Measurements and units in chemistry.

*

The language of chemistry

PRACTICE Chemical calculations The properties of gases. Concentration of solutions. The physical properties of solutions. Thermochemistry. Stoichiometry. Electrochemistry. Chemical equilibrium. Chemical equilibrium in solutions. Rate of chemical reactions. Laboratory experiments


* * *

*

*

* *

* *

* *

*

*

* *

* *

Atoms, molecules and formulas. The law of constant composition. The law of multiple proportions. Chemical formulas and names. Balanced chemical equations. Important types of chemical reactions. States of substances. Net ionic equations. Energy changes in chemical processes. Stoichiometry States of matter States of matter. Vapour pressure. The gaseous state. The ideal gas equation. Dalton's law of partial pressure. The kinetic theory of gases. Derivation of Boyle's law. Kinetic energy and temperature. Effusion and diffusion. Molecular speeds. Real gases. Critical phenomena. The structure of atoms

261 Separation of NaCl-CaCO3 mixture by solvation and filtration. Preparation of distilled water and its comparison with tap water by simple analysis.

Separation of the components of a mixture by sublimation. Undercooling. Preparation of solutions. Solubility studies. Study on the phenomenon of osmosis. Purification of crystalline potassium-aluminium sulphate by recrystallization.

Determination of the equivalent mass of magnesium. Determination of the molar volume of gases. Determination of the equivalent mass of zinc. Titration of NaOH solution with oxalic acid solution.

The development of the atomic theory. The electron. Xrays and radioactivity. The nuclear atom. The development of the quantum theory. The photoelectronic effect. The Bohr model of the hydrogen atom. Waves and particles. The quantum mechanical description of the hydrogen atom. Atoms, electrons, the periodic table Preparation of different types of chemical compounds. Preparation of a double salt. The quantum mechanical description of the hydrogen Study of heat of the solution. Determination of the atom. Electronic configuration of multielectron atoms. heat capacity and the approximate atomic mass of a Electrons in multielectron atoms. Ionization energy. metal. Electron affinity. The periodic table of elements. Periodic trends in atomic sizes. A group trend exemplified: the alkali metals. Periodic trends in the oxides, hydrides and haloides of elements. The chemical bond Electrochemical reactions. Transformation of chemical energy into electrical energy. Ionic bonds. The covalent bond. Electronegativity and Oxidation of iodide ions to iodine. Oxidation bonding. Lewis structures. Resonance. Overlap of atomic reactions by KMnO4. orbitals. The molecular orbital method. Oxidation number. Weak interactions. Molecular structure and stability Oxidation reactions by Fe(III) ions. Oxidation reaction by H2O2. Molecular properties and geometry. Thermochemistry. Effect of concentration on the rate of reaction. Oscillating reactions. Temperature dependence of reaction rate. Effect of catalysts on reaction rate. The properties of solutions Equilibrium constant. Hydrolysis of salt. Effect of temperature on the hydrolysis. Buffer solutions. Solubility of NaCl. Terminology. Expressions of concentrations. Solubility. Vapour pressure of solutions. Boiling point and freezing point of solutions. Osmotic pressure. Solutions of electrolytes. Colloids. Chemical equilibrium The equilibrium state and the equilibrium constant. The principle of Le Chatelier. Calculation of gas phase equilibrium constant. Solutions of sparingly soluble substances: the solubility product. Qualitative analysis by selective precipitation. Acids and bases Definitions of acids and bases. Strength of acids and bases. Acid and base strength and chemical structure. Acid and base reactions in aqueous solution. Weak acids and weak bases. Neutralization and titration. Buffers.

262 Polyprotic acids. * *

* *

* *

Oxidation-reduction Oxidation-reduction reactions. Oxidation-reduction processes in aqueous solution. Electrolysis and Faraday's laws. Galvanic cells. Cell potentials. Electrode potentials. Potential and concentration. The nernst equation. Some important electron transfer processes. Chemical kinetics Rate of reaction. Reaction rate and concentration. Rate law and reaction mechanism. Reaction rate and temperature. Reaction rate and equilibrium. Catalysis. Coordination chemistry Structure of coordination compounds. Isomerism of coordination compounds. Bonding of coordination compounds. Lability and stability of coordination chemistry. Complex ions in aqueous equilibria. Some applications of coordination chemistry.

INORGANIC CHEMISTRY 2nd semester

*

*

*

*

*

*

Classification of the elements based on the periodic table. Physical properties of the elements. Occurrence of the elements, isotopes. Synthesis and purification of the elements. General reaction routes of the elements. HYDROGEN Its place in the periodic table, electron configuration, physical properties, ortho and para hydrogen, isotopes of hydrogen, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (hydrides). NOBLE GASES Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them. Their chemical properties, reactions, synthesis and use of some important compounds containing them. ALKALINE METALS Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them. Ammonia solution of alkaline metals. Their chemical properties, reactions, synthesis and use of some important compounds containing them (alkaline hydrides; oxydes; hydroxides; halogenides; complex compounds; cryptates; biological importance). ALKALINE EARTH METALS Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them. Their chemical properties, reactions, synthesis and use of some important compounds containing them (calcium oxide; hydroxide; chloride; sulphate; EDTA complex; barium chloride, sulphate). BERYLLIUM Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it. BORON


*

*

*

*

*

*

*

*

*

Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (borides; boron halogenides; boranes; borax; boric acid). MAGNESIUM Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (oxyde; carbonate; sulphate; chlorophyll; Grignard compounds). ALUMINIUM Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing them (oxyde; sulphate; trichloride; hydroxide; alumen). SILICON Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it (glasses). Its chemical properties, reactions, synthesis and use of some important compounds containing it (oxydes; silicic acid; silicates; halogenides; silicons; siloxanes). GERMANIUM, ARSENIC, ANTIMONY Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them. Their chemical properties, reactions, synthesis and use of some important compounds containing them (arsenic oxydes; acids; antimony pentafluoride - super acids; antimony pentasulphide; bismuth nitrate). COPPER, SILVER AND GOLD Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them. Their chemical properties, reactions, synthesis and use of some important compounds containing them (copper sulphate; halogenides; silver nitrate; silver halogenides-photochemistry; gold chlorides). ZINC, CADMIUM AND MERCURY Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them. Their chemical properties, reactions, synthesis and use of some important compounds containing them (zinc oxyde; chloride; sulphate; metals dissolved in mercury; mercury chlorides; oxyde). TIN, LEAD AND BISMUTH Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them (radiation protection). Their chemical properties, reactions, synthesis and use of some important compounds containing them (oxydes; acetate). TRANSITION METALS General physical and chemical properties, electron configuration, occurrence, synthesis, use of them, important compounds (hydrides; Cr-oxydes, acids; Mnoxydes, acids and bases; Fe-oxydes, hydroxydes, complex compounds; Ni, Pd, Pt, Rh, Ir-catalysis). IRON

263

264

*

*

*

*

*

*

*

*

*

Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (iron; iron trichloride; sulphate; hemoglobine). RARE EARTH METALS General physical and chemical properties, electron configuration, occurrence, synthesis, use of them, important compounds (Ce-oxydation; Sm-pharmaceutical use; Th-physical properties; U-separation of the isotopes). FLUORINE Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (hydrogen fluoride, fluorides- caries prevention). CHLORINE Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (chlorine water; acids; salts of the acids). BROMINE AND IODINE Their place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of them. Solvatation of iodine. Their chemical properties, reactions, synthesis and use of some important compounds containing them (bromine water; hydrogen bromide, bromides-sedatives; oxoacids and salts; iodine solutions; pseudohalogenides; biological importance of iodine). OXYGEN Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Water (natural-, deionised, distilled water; physical properties; water as solvant). Its chemical properties, reactions, synthesis and use of some important compounds containing it. Substances for oxydation (peroxides, permanganates, chlorine water, iodine etc.) SULFUR Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it (ozone, natural, deionised and distilled water, hardness of water, hydrogen peroxyde). Its chemical properties, reactions, synthesis and use of some important compounds containing it (sulfides; acids; salts and acid derivatives containing sulfur). NITROGEN Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (ammonia, ammonium salts; oxides; acids; hydrazine; carbamide; azides). PHOSPHORUS Its place in the periodic table, electron configuration, physical properties, occurrence, synthesis and use of it. Its chemical properties, reactions, synthesis and use of some important compounds containing it (oxydes, acids, salts and their biological importance). CARBON


265

Its place in the periodic table, electron configuration, physical properties, isotopes of carbons, occurrence, synthesis and use of it (charcoal). Its chemical properties, reactions, synthesis and use of some important compounds containing it (carbides; carbon monoxide; carbon dioxide; acids; carbonates; hydrogencarbonates; antacid substances). PHARMACEUTICAL BIOLOGY *

Structure and biological functions of large macromolecules: lipids,carbohydrates, proteins, nucleic acids.

*

Comparison of eukaryotic and prokaryotic cells. Organization and biological function of nuclei, endoplasmic reticulum, ribosomes, Golgi complex, secretion vesicules, mitochondria and peroxisomes.

*

Components of cytoskeleton. Cellular movement. Cell adhesion and cell junctions.

*

DNA, gene, genom epigenome and chromosomes.

*

Replication and cell division.

*

Mendelian genetics, dominant- recessive, sex-linked mode of inheritance. Most frequent genetic disorders linked to autosomes and X chromosomes in humans.

*

Prokaryotic and eukaryotic geneexpression stratagies: transcription posttranscriptional processing, translation posttranslational modifications.

*

Regulation of geneexpression in prokaryotes and eukaryotes.

*

Principles of molecular biological technics: molecular cloning, RFLP, PCR, blottings, FISH.

*

The cell cycle and its regulation, cellular aging and programmed cell death

*

Molecular biology of cancer formation.

*

Biology of the immune system.

*

The most common signaltransduction pathways and their role in cellular functions.

*

Basics of pharmacogenomics: history of Gleevec, Herceptin.

ANATOMY 1st semester

* * * * * * * * * * * * * *

LECTURE (2 hrs/week) Morphology of the cell I. Morphology of the cell II. Morphology of the cell III. Epithelial tissues Connective tissues Bone and cartilage Muscle tissues Nervous tissue The parts of the human body The bones of the human body The joints of the human body The main skeletal muscles The anatomy of the heart and large vessels The anatomy of the respiratory tract (nasal cavity, larynx and lungs)

2nd semester

*

LECTURE (2 hrs/week) The anatomy of the digestive system I.

266 * * * * * * * * * * * * *

The anatomy of the digestive system II. The anatomy of the kidney and other organs of the urinary tract The anatomy of the female genital organs The anatomy of the male genital organs The histology of the ovary and testis (gametogenesis) The anatomy of the andocrine glands (principles of endocrine regulation) The anatomy of the central nervous system: the spinal cord The anatomy of the central nervous system: the brain stem and the cerebellum The anatomy of the central nervous system: diencephalon, basal ganglia, cortex cerebri The anatomy of the meninges and the cerebral ventricles The anatomy of the peripheral nervous system Human development I. Human development II.

QUALITATIVE CHEMICAL ANALYSIS * * *

* * * * *

*

* *

* *

* *

Concepts, aims and general methods. Ions. Classification of reactions. Redox reactions. (Oxidation number /oxidation state/. Oxidation and reduction.) Acid-base reactions. Reactions involving precipitation. Complex-formation reaction (Complex cations. Complex anions. Neutral complexes. Chelates.) Reaction sensitivity Reaction specificity Groups of cations Group 1: Hydrogen sulphide group. Group reaction. Reagents. General characterization of group 1. Group 1A (hydrochloric acid sub-group): Silver(I), reaction with hydrogen sulphide, hydrochloric acid, bromides and iodides, alkali hydroxides, ammonia, chromates. Lead(II), reaction with hydrogen sulphide, chlorides, iodides, sulphates, alkali hydroxides or ammonia, chromates. Mercury(I), reaction with sulphides, chlorides, ammonia, alkali hydroxides, iodides, metallic copper. Group 1B (copper sub-group): Mercury(II), reaction with sulphides, ammonia, alkali hydroxides, tin(II) chloride, iodides, metallic copper. Copper(II), reaction with sulphides, ammonia, alkali hydroxides, hexacyanoferrate(II), cyanides, iodides, metallic iron or zinc, flame coloration. Bismuth, reaction with sulphides, alkali hydroxides or ammonia, water, hydrolysis, tetrahydroxostannate(II), iodides. Cadmium(II), reaction with sulphides, alkali hydroxides, ammonia, cyanides. Simple analysis of cation group 1. Group 2 (arsenic group): Group reaction. Reagents. Arsenite arsenic(III), reaction with sulphides, silver ions, iodine, Marsh reaction, Bettendorf reaction, Gutzeit test, Sanger-Black test, heating test. Arsenate arsenic(V), reaction with sulphides, silver ions, Marsh, Bettendorf, Sanger-Black and Gutzeit reactions, magnesia mixture. Antimony(III), reaction with sulphides, water, hydrolysis, alkali hydroxides or ammonia, metallic zinc or iron, Marsh, Sanger-Black and Gutzeit test. Antimony(V), reaction with sulphides, iodides. Tin(II), reaction with sulphides, mercury(II), alkali hydroxides, metallic zinc, luminescence test. Tin(IV), reaction with sulphides, alkali hydroxides, metallic zinc, metallic iron. Simple analysis of cation group 2. Group 3 (ammonium sulphide group): Group reaction. Reagents. Cobalt(II), reaction with ammonium sulphide, alkali hydroxides, ammonia, cyanides, thiocyanates, nitrites, Borax-bead test. Nickel(II), reaction with ammonium sulphide, ammonia, alkali hydroxides, cyanides, dimethylglyoxime. Iron(II), reaction with ammonium sulphide, alkali hydroxides or ammonia, hexacyanoferrate(III), ,-dipyridyl, permanganate. Iron(III), reaction with ammonium sulphide, hydrogen sulphide, ammonia or alkali hydroxides, sodium acetate, hexacyanoferrate(II), thiocyanate, iodides. Chromium(III), reaction with ammonium sulphide, ammonia, alkali hydroxides, hydrogenperoxide. Oxidation to chromate in melt phase. Chromate, reaction with sulphides, ethanol, silver ion, barium ions, peroxichromate reaction. Aluminium(III), reaction with ammonium sulphide, ammonia, alkali hydroxides, alizarinsulphonate, Thénard-blue test. Zinc(II), reaction with ammonium sulphide, ammonia, alkali hydroxide, hexacyanoferrate(II), Rinmann-green test. Manganese(II), reaction with ammonium sulphide, ammonia or alkali hydroxides. Oxidation to permanganate with lead(IV). Oxidation to permanganate with persulphate. Oxidation in the melt phase. Permanganate, reaction with sulphides, peroxides, ethanol. Simple analysis of cation group 3. Group 4, alkaline earth (ammonium carbonate) group: Group reaction. Reagents. Calcium(II), reaction with ammonium carbonate and carbonates, sulphates, oxalates, phosphates, hexacyanoferrate(II), chromate. Visible spectrum. Strontium(II), reaction with ammonium carbonate and carbonates, sulphates, lime water, oxalate, phosphates, chromate. Visible spectrum, flame coloration. Barium(II), reaction with ammonium carbonate and carbonates, sulphates, calcium or strontium sulphate, oxalates, phosphates, chromate or dichromate. Visible


* * *

*

*

* *

* *

267 spectrum, flame coloration. Simple analysis of cation group 4. Group 5, magnesium and alkali metal group (soluble group): Group reaction. Magnesium(II), reaction with ammonia, alkali hydroxides, ammonium carbonate, phosphates, quinalizarine. Sodium(I), reaction with antimonate, zinc uranylacetate. Visible spectrum, flame coloration. Potassium(I), reaction with tartaric acid, hexanitrocobaltate(III), perchloric acid, tetraphenylboron. Visible spectrum, flame coloration. Ammonium(I), reaction with tartaric acid, hexanitrocobaltate(III), tetraphenylboron, strong bases, Nessler reaction. Lithium(I), reaction with ammonium carbonate, phosphates. Visible spectrum, flame coloration. Simple analysis of cation group 5. Groups of anions. Group 1: Carbonate, reaction with acids, hydrolysis (phenolphthalein), magnesium sulphate. Hydrogencarbonate, reaction with acids, hydrolysis, magnesium ions. Sulphite, reaction with acids, barium ions, silver ions, iodine. Thiosulphate, reaction with acids, silver ions, iodine. Heating in flame. Sulphide, reaction with acids, nitroprusside, Hepar-reaction. Polysulphide, reaction with acids. Silicate, reaction with dilute acids, molybdate. Tetrafluoride test. Hypochlorite, formation and reaction with acids. Group 2: Group reaction. Sulphate, reaction with barium ions, lead ions, Hepar reaction. Water-insoluble sulphates. Phosphate, reaction with barium ions, silver ions, magnesia mixture, molybdates. Borate, reaction with barium ions, silver ions. Turmeric paper reaction. Flame coloration. Fluoride, reaction with barium ions, calcium ions, silver ions, sulphuric acids, thiocyanates. Tetrafluoride test. Bromate, reaction with barium ions, silver ions, bromides, concd. hydrochloric acid, metallic zinc. Iodate, reaction with barium ions, silver ions, iodides, concd. hydrochloric acid, metallic zinc. Group 3: Group reaction. Chloride, reaction with silver ions, Chromyl chloride reaction, Berg reaction, oxidative agents. Bromide, reaction with silver ions, chlorine water, permanganate. Iodide, reaction with silver ions, chlorine water, iron(III) ions, oxidants. Cyanide, reaction with silver ions, hexacyanoferrate(II) reaction, acids (HC1), iodine or bromine. Thiocyanate, reaction with silver ions, iron(III) ions. Group 4: Group reaction. Nitrate. Brown-ring test. Reduction with metallic zinc in alkaline medium. Nitrite, reaction with strong acids, iron(II) ions, Griess-Ilosvay reaction, urea, permanganate oxidation, iodide, metallic zinc. Acetate, reaction with strong acids, iron(III) ions. Esterification. Decarboxylation with calcium oxide. Chlorate, reaction with strong acids, disproportionation by heating, concd. sulphuric acid, iodides, metallic zinc. Perchlorate, reaction with iodides, metallic zinc, potassium ions. Methylene blue reaction. Total analysis of solids for cations and anions: physical appearance, color, preliminary tests, heating, flame coloration, preparation of solution, analysis for cations and anions. Identification of anions in mixtures: Chloride, bromide and iodide. Chloride and iodide. Bromide, iodide and nitrate. Nitrite and nitrate.

QUANTITATIVE CHEMICAL ANALYSIS 2nd semester

*

*

*

*

LECTURE The nature, role and importance of quantitative analytical chemistry in the industry, research and medical practice. The fundamental concepts and methods of analytical chemistry. The measuring equipment and their calibration used in analytical chemistry. The sampling, sample treatment and preparations, techniques in component concentration and separation. Dissolving, fusion, mineralization of the samples. Basic principles of gravimetry solubility of precipitates, factors influencing the solubility of pracipitates. Mechanism and conditions of analytical precipitation. Impurities in precipitates. Techniques used in precipitation. Washing, filtering, thermal treatment and weighing of precipitates. Calculating the gravimetric results. Gravimetric determination of cations and anions. Precipitates formed by organic reagents. Principles of titrimetric methods. Volumetric glassware and their calibration. Preparation and standardization of titrants. End-point determination techniques in titrimetry. Calculation of results, error calculation and their sources.

PRACTICE Introduction:

Health and accident prevention regulations.

The use of volumetric glassware.

Procedure of chemical analysis.

268 * Acid-base theories, ionization of strong and weak acids, bases and their salts, calculation of pH. Classification and characterization of solvent used in acid-base titration. Construction of titration curves. Detection of end-point, mechanism of indication, indicator exponent. Preparation and standardization of titrants in acid-base titration. Titration of strong and weak acids, bases and their salts. Titration of alkali carbonate, bicarbonate and hydroxide mixture. The hardness of natural waters. The role of acid-base titrationin analysis of trigycerids (fats and oils). Acid-base titration in nonaqueous solution. * Principles of precipitate forming titration. Calculation of solubility and construction of titration curves. End-point detection methods in precipitate forming titration. Preparation and standardization of silver nitrate titrant. Determination of silver ions, halogenides and pseudohalogenides. * Complex equilibrium in analytical chemistry, theory of complexometric titration. Influence of pH and the presence of other complex forming reagents on stability of complexes. The selectivity of complex forming titration. Indication of end-point by visual and instrumental methods. Preparation and standardization of EDTA solution. Direct, indirect and back titration in complexometry. Determination of hardness of waters. * Redox equilibrium in analytical chemistry. Influencing factors on redox potential. Calculation of redox potential change during the titration, construction of titration curve. Role of induced reactions and catalysis in redox titrations. Indication methods of end-point, mechanism of indications, influencing factors on redox indicators. * Preparation and standardization of potassium permanganate solution. Direct, indirect and back titration in permanganometry. * Preparation and standardization of the titrants in cerimetry and chromatometry. Cerimetric and chromatometric determination of iron(II), hydrogenperoxide, alcohols and organic acids. Determination of chemical oxygen demand of natural waters. * Influencing factorsin bromatometric redox systems. Preparation of titrant in bromatometry. Determinations based on addition and substitution reactions of organic compounds with bromine. Direct titration with potassium bromate standard solution determination of As(III), ascorbic-acid, azophenum. Back titrations in bromatometry. Determination with brominechloride. * Preparation and standardization of iodine and sodiumthiosulfate standard solution. End point indication in iodometry and iodimetry. pH dependence on iodometric titrations. Determination of oxidizing agents titration of halogens, hypohalogenides, halogenites, halogenates and metallic oxides. Determination of dissolved oxygen in waters. Determination of reducing agents titration of sulfides, sulfites, aldehydes, saccharides. Water determination by Karl Fischer methods. * Reductometric methods titanometry, ascorbinometry. *

Instrumental methods of chemical analysis, classification and importance of instrumental analysis.

Calculation of analytical results and solving of problems.

Gravimetry:

Gravimetric determination of sulfate ion in form of BaSO4.

Gravimetric determination of and calcium ion sin form of CaC2O4*H2O.

Acidi- and alkalimetry:

Preparation and standardization of hydrochloric acid and sodium hydroxide standard solution.

Titration of week acids (acetic acid).

Titration of a mixture of strong and week acids (sulphuric and boric acid).

Determination of sodium thiosulphate (multiplying procedure). Determination of amonia in amonium salts by destilation.


*

*

*

Electrochemical methods potentiometry (membrane-type and special electrodes) and potentiometric titrations, electrolytic methods (polarography, volt-ammetric titrations), coulombmetry and measurements based on electric conductivity. Spectrometric methods in instrumental analysis, interaction of electromagnetic radiation with matter. General rules of light absorption and emission. Excitation methods in atomic emission spectroscopy. Principles and applications of atomic absorption. Ultraviolet visible and infrared spectrophotometry. Fluorometric methods. Separation methods of instrumental analysis. Principles and applications of gas chromatography, high performance liquid chromatography and ionchromatography. Basic principles of resonance methods (NMR, ESR) and mass spectrometry.

* * *

269 Determination of potassium ion by ion exchange separation.

Argentometry:

Preparation and standardization of silver nitrate and potassium thiocyanate titrant.

Titration of bromide ion by Volhard method (back titration). Instrumental analysis: Spectrophotometry: determination of salicylic acid Flame photometry: determination of alkaline ions

FIRST AID AND RESUSCITATION * * * * * * * * * * * *

*

The principles of first aid and emergency situation. Constantin’s cross. Victim assessment. Rescuing technique. Rautek’s manoeuvre, log-roll technique, KED, paramedic-EMC-NIC introducing, helmet removing. Unconscious patients, BLS, XBLS, AED Unconscious patients, BLS, XBLS, AED – practice Obstructed airway emergencies. Choking. Submersion. Respiratory distress. Heimlich manoeuvre. Stable position (Gabor’s manoeuvre). Esmarch-Heiberg manoeuvre. Laryngeal mask, ET. Bleeding. Mechanism of injuries (joints, bones). Pain relief. Recognition of patients with shock conditions. Capeline bandage. Dessault dressing. Art. pressure points. Art. pressure bandages. Venous pressure dressings. Stifneck, VM, pneumatic splints. Scoop strecher. Mechanism of injuries. Type of wounds. Burn injuries. Electrical accident. Rescuing technique. First aid technique. Recognition of poisoning. First aid on the scene. Repeat: BLS, opening airways, ventilation, chest compression, stopping the bleeding, application of bandage, splinting technique, immobilization technique, Trendelenburg position, log-roll, Rautek, Heimlich, helmet removing, stabilization of body. Final examination.

SHORT HISTORY OF HUNGARY I –II. 1st semester * Geography, population, political system of Hungary * Brief history of Szeged * Origin of the Hungarians, Finno-Ugric language relationship, ancient history * Early Middle Ages, foundation of the Hungarian State * Hungary as a Central European power, age of the Anjou dynasty * Age of János and Mátyás Hunyadi * Written test I * Art, architecture and culture in Medieval Hungary * Ottoman Turkish conquest, tripartite division of Hungary * Efforts to unify the country, the Principality of Transylvania * Reform movements in Western Christianity, main characteristics of Christian denominations * Liberation of Hungary, Rákóczi rebellion, Hungary as a part of the Habsburg Empire * Written test II 2nd semester * Reform era of 1825-1848, activities of Széchenyi and Kossuth * Revolution and war of independence of 1848-49 * Compromise in 1867, formation of Austro-Hungarian Monarchy

270 * Brief history of Budapest * World War I, dismemberment of Austro-Hungarian Monarchy * Written test I * Interwar period, Horthy regime * Hungary in World War II * Hungary after World War II, Hungary as a part of the Soviet block * Revolution in 1956 * Kádár regime and its fall, elections of 1990 * Outstanding Hungarian scientists, artists, athletes of modern times * Written test II ENGLISH 1st semester

* * * * * * * * * * * * * *

PRACTICE (2 hrs/week) Introduction and group discussion. Interviewing: asking and answering Yes/No and Wh-questions. Reading comprehension: skimming texts, understanding the essence of texts. Reading and discussing articles about hot issues on diseases and their cures. Vocabulary expansion, reading about recent advances in pharmacology. Video watching and discussion on the same topic. Writing tasks: how to write an essay/composition. Briefing task: reading a longer text (n=1500) on chemistry and summarizing it in 500 words. The use of connectors in writing. Listening skills: listening to a recording on vitamins and their effects, note taking exercise. Practising the Passive Voice. Speaking skills: preparing talks and mini-presentations. Paraphrasing and the use of references in presenting mini-projects. The use of Modal Verbs. Revision of the Past Simple and the Present Perfect Tenses. Presenting research methods and results. Mid-term test. Guided note taking. Listening to a recording on pathogens and taking notes. Comparing and discussing notes. Identifying main points. Semantic markers. Reading skills: preparing study notes from lengthy texts, identifying most important facts. Description, cause and effect. Understanding and memorizing definitions. Focussing on grammar and vocabulary expansion: CFC practice tests and health vocabulary tests. Video-watching: eating disorders – anorexia, bulimia and binge eating. Summarizing the film in writing and giving opinion on the topic. The use of definite and indefinite articles. Preparing short oral presentations on harmful habits. Arguing and defending viewpoints. Preparing for discussions. Indirect speech. Guided note taking. Listening to a recording on constipation and its cures. Developing patient advice leaflets from notes. Vocabulary and grammar revision. Practice tests. Final test.

2nd semester

* * * * * * * *

PRACTICE (2 hrs/week) Organizing written notes and identifying main points. Lecture notes taken from Biology. Commonly used abbreviations and their interpretation. Video watching: psoriasis and its treatment modalities. Medicaments used externally. Group discussion of a video film, arguing and convincing. Essay writing on the importance of the pharmacist in giving advice on a healthy diet. Suggestions and recommendations. The use of MUST/SHOULD/WOULD. Reading skills: developing faster reading and deeper understanding of read texts. Accomplishing reading comprehension tasks. CAE Reading Test. Vocabulary expansion: preparing word-nets concerning internally used medicines. Adjectives, Comparatives and Superlatives. Making use of the Internet in class: searching the Net for information on certain health issues. Presenting ideas found on the Net. Group discussion and evaluation. Revision of Future Tenses and expressions meaning intension and certainty in the future. Describing expected and adverse effects of drugs. Mid-term test. Developing awareness of proper and improper sentence constructions, grammar and vocabulary. Error spotting in essays written by group mates.

Curriculum 2014/2015 * * * * * *

271 Clear and concise writing. How to make our writing more effective? Practising short essay writing, analysing problems of English from in biology and chemistry texts. Repetition and reformulation of ideas. Reading and understanding Tables. Numericals, decimals, reading out numbers. Reading and presenting graphs. The Conditional Mood. Vocabulary expansion: preparing word-nets concerning shapes. Vocabulary expansion: English words of Greek and Latin origin in the field of Pharmacy. Prefixes and suffixes giving oppositional meaning to adjectives and adverbs. Listening and writing skills: listening to a recording on the drug industry and taking notes. Comparing and discussing notes. Defining and non-defining relative pronouns. Vocabulary and grammar revision. CAE and Medical Practice tests. Final test.

LATIN 1st semester

* * * * * * * * * * * * * *

PRACTICE (2 hrs/week) The role of the Latin language in medicine and pharmacy. Pronunciation. Groups of nouns - typical forms. Noun-adjective agreement, grammatical gender. 1st declension. Noun-adjective agreement, grammatical gender. Cases. Preas. Imp. Activi form of Latin verbs. Simple medicine forms. Plural forms in 1st declension..Prepositions. Praes. Imp. Passivi. 2nd declension. Grammar revision excercises. Ointment, oil. Mid-term test. The stucture of medical prescriptions. 3rd declension - nouns. 3rd declension - adjectives. Prepositions. Medicine forms. The structure of medical prescriptions. Abbreviations. Cardinals in prescriptions. Miscellaneous exercises. Cardinals - "gramma". 4th declension. Herbal teas. 5th declension. Comparison of adjectives. Participles in the pharmaceutical language. Herbs and plants. Revision. Final test.

272 HUNGARIAN LANGUAGE 1st semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) Introduction: general information about the language. The Hungarian alphabet, pronunciation and intonation. Greetings, notices. Getting acquainted: Who are you? Where are you from? Conjugation of the verb ‘to be’, subject form of the personal pronouns. What is where in Szeged? Asking questions. Question words, existential sentences. Definite and indefinite articles. Meeting students. The conjugation of verbs: present indefinite conjugation, singular forms. Cardinal numbers: telephone numbers and prices. Going shopping. The accusative form of nouns. Revision of grammar and vocabulary. Going to the cinema. Telling the time. Making an appointment. Plural forms of the verb (indefinite present tense). The postposition ‘elıtt’. TEST 1 A Sunday out: museum, theatre. The plural form of nouns and adjectives. Expressing possibility. The infinitive form. Buying cinema tickets. Practising the present tense indefinite conjugation. Some adverbial suffixes: ba/-be (to, into), -ban/-ben (in) In a restaurant. Ordering a meal. Further adverbial suffixes: -hoz/-hez/-höz (to), -nál/-nél (at) General revision. TEST 2 Oral tests

2nd semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) My family:possesive suffixes, genitive structure. I have a…:Possesives+case endings. Expressing possession. What is your friend like:describing people. Calendar, dates. Revision TEST 1 Students life: review of indefinite conjugation. Transitive and intransitive verbs. Definite conjugation. Daily routine: verbal prefixes. Finding a flat: suffixes tól/tıl, hoz/hez/höz, ra/re. Compound nouns. Weather and seasons. General revision. TEST 2 Preparation for the oral exam. Oral tests

BASIC COMMUNICATION (ELECTIVE COURSE) 1. Introduction, motivation 2. Definition of communication, elements and basics of interpersonal communication, Factors influencing communication 3. Belbin test, human characters and their handling 4. Movie 5.

Body language

6.

Active listening, I and You language

7.

Summary: situations, practice

Curriculum 2014/2015 8. 9.

Verbal communication elements: assertivity, win-win communication Presentation skills

273

274 SYLLABUSES FOR 2ND YEAR PHARMACY STUDENTS QUANTITATIVE CHEMICAL ANALYSIS 3rd semester

*

*

*

*

*

*

*

LECTURE The nature, role and importance of quantitative analytical chemistry in the industry, research and medical practice. The fundamental concepts and methods of analytical chemistry. The measuring equipment and their calibration used in analytical chemistry. The sampling, sample treatment and preparations, techniques in component concentration and separation. Dissolving, fusion, mineralization of the samples. Basic principles of gravimetry solubility of precipitates, factors influencing the solubility of pracipitates. Mechanism and conditions of analytical precipitation. Impurities in precipitates. Techniques used in precipitation. Washing, filtering, thermal treatment and weighing of precipitates. Calculating the gravimetric results. Gravimetric determination of cations and anions. Precipitates formed by organic reagents. Principles of titrimetric methods. Volumetric glassware and their calibration. Preparation and standardization of titrants. End-point determination techniques in titrimetry. Calculation of results, error calculation and their sources. Acid-base theories, ionization of strong and weak acids, bases and their salts, calculation of pH. Classification and characterization of solvent used in acid-base titration. Construction of titration curves. Detection of end-point, mechanism of indication, indicator exponent. Preparation and standardization of titrants in acid-base titration. Titration of strong and weak acids, bases and their salts. Titration of alkali carbonate, bicarbonate and hydroxide mixture. The hardness of natural waters. The role of acidbase titrationin analysis of trigycerids (fats and oils). Acid-base titration in nonaqueous solution. Principles of precipitate forming titration. Calculation of solubility and construction of titration curves. End-point detection methods in precipitate forming titration. Preparation and standardization of silver nitrate titrant. Determination of silver ions, halogenides and pseudohalogenides. Complex equilibrium in analytical chemistry, theory of complexometric titration. Influence of pH and the presence of other complex forming reagents on stability of complexes. The selectivity of complex forming titration. Indication of end-point by visual and instrumental methods. Preparation and standardization of EDTA solution. Direct, indirect and back titration in complexometry. Determination of hardness of waters.

PRACTICE Complexometry:

Preparation and standardization of EDTA standard solution.

Determination copper(II)-ion.

Titration of calcium- and magnesium ions in mixture.

Permanganometry:

Preparation and standardization of potassiumpermanganate standard solution.

Titration of hydrogen-peroxide.


275

*

Redox equilibrium in analytical chemistry. Influencing factors on redox potential. Calculation of redox potential change during the titration, construction of titration curve. Role of induced reactions and catalysis in redox titrations. Indication methods of end-point, mechanism of indications, influencing factors on redox indicators.

*

Preparation and standardization of potassium Bromatometry: permanganate solution. Direct, indirect and back titration in permanganometry. Preparation and standardization of the titrants in Preparation of potassium bromate standard cerimetry and chromatometry. Cerimetric and solution. chromatometric determination of iron(II), hydrogenperoxide, alcohols and organic acids. Determination of chemical oxygen demand of natural waters.

*

Determination of iron(II) ion.

*

Influencing factorsin bromatometric redox systems. Titration of arsenic(III) ion by Gyıry. Preparation of titrant in bromatometry. Determinations based on addition and substitution reactions of organic compounds with bromine. Direct titration with potassium bromate standard solution determination of As(III), ascorbic-acid, azophenum. Back titrations in bromatometry. Determination with brominechloride.

*

Preparation and standardization of iodine and Determination of antipyrin by bromine substitution sodium-thiosulfate standard solution. End point reaction. indication in iodometry and iodimetry. pH dependence on iodometric titrations. Determination of oxidizing agents titration of halogens, hypohalogenides, halogenites, halogenates and metallic oxides. Determination of dissolved oxygen in waters. Determination of reducing agents titration of sulfides, sulfites, aldehydes, saccharides. Water determination by Karl Fischer methods.

*

Reductometric methods titanometry, ascorbinometry. Instrumental methods of chemical analysis, classification and importance of instrumental analysis. Electrochemical methods potentiometry (membranetype and special electrodes) and potentiometric titrations, electrolytic methods (polarography, voltammetric titrations), coulombmetry and measurements based on electric conductivity.

*

*

*

*

* * *

Jodometry: Preparation and standardization of sodiumthiosulfate solution. Determination of phenol by Koppeschaar.

Spectrometric methods in instrumental analysis, Titration of thiocyanate ion by Schulek. interaction of electromagnetic radiation with matter. General rules of light absorption and emission. Excitation methods in atomic emission spectroscopy. Principles and applications of atomic absorption. Ultraviolet visible and infrared spectrophotometry. Fluorometric methods. Separation methods of instrumental analysis. Jodometric determination of copper(II) ion. Principles and applications of gas chromatography, high performance liquid chromatography and ionchromatography. Basic principles of resonance methods (NMR, ESR) Instrumental analysis: and mass spectrometry. Conductometric titration: determination of oxalic acid Coulombmetry: determination arsenic(III) ion

276 * *

Potentiometry: alkalimetric titration of phosphoric acid, cerimetric titration of iron(II)-ion by potentiometric end point indication Voltametry: iodometric titration of iodate by byamperometric end point detection Chromatograpy: gas chromatographic analysis of alcohols or HPLC measurement of phenolic compounds

* *

PHYSICAL CHEMISTRY

* * * *

LECTURE Thermodynamics The first law of thermodynamics The second law of thermodynamics The third law of thermodynamics

* *

Phase equilibrium Chemical equilibrium

* *

Electrochemical equilibrium Iontransport

* *

Reaction kinetics

* *

PRACTICE Thermochemistry Determination of the heat of neutralization. Phase equilibria Determination of vapour pressure and heat of vaporisation of a liquid. Determination of the partial molar volume. Solubility relations in a three component system. Determination of boiling point diagram of two component miscible liquids. Partition experiments. Solubility measurements of solid substances. Reaction kinetics Temperature dependence of the decomposition of a medicine. The kinetics of the hydrolysis of methyl acetate. The study of catalysis, promotion and inhibition. Primary salt effect on the kinetics of ionic reactions. Study of the kinetics of the decomposition of benzene-diazonium-chloride. Determination of initial rate and order of a reaction by clock reaction. Electric conductance Study of dissociation by electric conductance. Dependence of conductivity on concentration. Solubility by conductivity measurements. Electromotive force Study of redoxy electrodes. Dependence of electrode potential on the concentration of electrolyte. Concentration cells. Determination of pH. Experiments based on optical methods Dependence of light refraction on the concentration. Study of absorption spectrum of solutions. Study of inversion of cane sugar by polarimetry. Study of complexes by spectrophotometry.

ORGANIC CHEMISTRY 3rd semester

*

LECTURE General introduction. Electronic theory and bonding in carbon compounds. Degree of oxidation, functional groups, families of organic compounds. Classification of organic transformations. General rules of nomenclature. Bond polarization.

PRACTICE Basic methods of synthetic organic chemistry; Distillation; Crystallization, melting point; Extraction;


*

*

*

*

*

*

*

Isomerism in organic chemistry: constitutional, conformational, configurational. Conformation, configuration. Stereoisomerism: geometric isomers (cis-trans), optical isomers, chirality. Central chirality, molecular asymmetry. Stereochemical characteristics of chemical transformations. Asymmetric synthesis, resolution. Tautomerization. Hydrocarbons. Saturated hydrocarbons (alkanes): structure, conformation. Free-radical halogenation. Unsaturated hydrocarbons (alkenes): mono-olefins, dienes. Electrophilic additions. Dienes, conjugation. Alkynes. Aromatic hydrocarbons: monocyclic, isolated, and condensed ring systems. Aromaticity, aromatic electrophilic substitutions. Substituent effects on aromatic SE reactions: reactivity and orientation. Organic halides. Nucleophilic substitutions and eliminations; stereochemistry. Structure and reactivity of organic halides. Compounds containing C–O and C–S single bonds. Alcohols and thio analogs: substitution, elimination, oxidation. Phenols and thio analogs. Acidity. Hydrogen bonding. Ethers and thio analogs: openchain and cyclic ethers. Crown ethers. Nitrogen-containing compounds. Nitro compounds. Amines: basicity, nucleophilicity. Alkylation, reactions with nitrous acid and carbonyl compounds. Biological and pharmaceutical importance of amines. Azo compounds, diazomethane, diazonium compounds. Carbonyl compounds. Aldehydes, ketones: general reactivity. Nucleophilic additions, condensations, oxidations, reductions. Carboxylic acids and derivatives. Acidity. Nucleophilic acyl substitutions: ester formation, ester hydrolysis. Carboxylic acid derivatives: general reactivity. Substituted carboxylic acids: dicarboxylic acids, ketoand hydroxy-carboxylic acids. Carbonic acid derivatives.

277 Reactivity of functional groups in organic compounds (hydrocarbons, halogeno compounds, hydroxyl derivatives, amino derivatives, carbonyl compounds, carboxylic acids and derivatives saccharides,

Syntheses (oxidation, reduction, nucleophilic substitution, electrophilic substitution, electrophilic addition, esterification, acylation, condensation, cyclocondensation, synthesis of representative compounds with pharmacological activities

4th semester

*

* * * * *

LECTURE Heterocyclic compounds. Saturated and unsaturated compounds. Aromatic heterocycles: five- and sixmembered rings with one or two heteroatoms. Benzo-fused derivatives. Aromaticity and reactivity. Tautomerization of aromatic heterocycles. Amino acids, peptides, proteins. Chemistry of a-amino acids. Synthesis and structure determination of peptides. Chemistry related to the structure of proteins. Carbohydrates. Structure and chemistry of monosaccharides. Di-, oligo- and polysaccharides. Nucleic acids. Building blocks of nucleic acids. Ribonucleic acids, deoxyribonucleic acids: the Watson-Crick model. Nucleotide coenzymes. Isoprenoids. Terpenoids, carotenoids, steroids. Alkaloids.

278 PHYSIOLOGY 3rd semester LECTURE Introduction, homeostasis

Membrane physiology

Transmission: synapsis, receptors Muscle physiology Blood physiology

Heart physiology

Circulation

Respiration physiology

Physiology of the urinary system

PRACTICE Information about work safety and fire protection. Recording technics, recording devices: kimograph, computer. Methods of stimulation: thermal, chemical, electrical, types of electrodes. Membrane potential and action potential observing with METANEURON system: ionic theory of the action potential, the threshold of action potential, stimulus strengths – duration relationship, refractory periods. Electromyography (EMG). Neuromuscular studies with BIOPAC system. Blood tests: The microscope in haematological tests, sterilisation and disinfection, methods of taking blood from the fingertip, centrifuges. Blood cells (HEMOSURF program), qualitative blood smear, hematocrit (micro). Observation of blood clotting (in vitro), determination of blood groups (AB0, Rh), prothrombin time. Using and cleaning of the melangeur pipettes, Bürker's chamber, red blood cell count, white blood cell count, osmotic resistance of red blood cells, observing reticulocytes in blood smear. Principles of: methods of taking blood from a vein, Price-Jones' curve, erythrocyte sedimentation rate by Westergren, bleeding time, partial thromboplastin time, thrombin time, International Normalized Ratio (INR), thrombocyte count (Fischer-Germer), reticulocyte count, staining index, haematological automata. Studies on the circulatory system: Experiments in the isolated rat heart preparation (Langendorf perfusion): effects of ions and drugs (adrenaline, acetylcholine, atropine) on the heart. Video: in situ registration of the activity of the heart in the frog. Human ECG: recording the human ECG, characteristics of the normal ECG, draw the electrical axis of the heart. The human circulatory system: peripheral pulse, characteristics of the radial pulse, blood pressure measurement, effects of breathing on the circulation, cold pressor test, investigation of the axon reflex flare (triple response of the skin), jugular pulse. The human respiratory system: spirometry, determination of inspiratory and expiratory pressures, palpation over the chest, auscultation over the heart and lungs. Technical information for the urine practice. Urine analysis: colour, smell, transparency and pH. Microscopic investigation of the urinary sediment (power point slide show). Specific gravity. Detection of: calcium (Sulkowitsch' test), glucose (Nylander's and Fehling's tests), proteins


Volumen-, osmo- and pH regulation

279 (Heller's test, boiling test, sulphosalicylic acid test), acetone (Rothera’s test,Legal’s test), bile pigments, UBG (Ehrlich's method), blood (benzidine test; theory), pus (theory). Rapid (strip) tests. Demonstration of the effect of ADH on the diuresis. Dilution and concentration test in human (theory). Counting corpuscular elements in urine (Addis' method, theory). Determination of clearance (theory).

Skin and thermoregulation 4th semester Physiology of the gastrointestinal system

Vitamins, nutrition, metabolism Endocrine system

Physiology and structure of the nervous system Motor system

Somatosensory system

Autonomous nervous system

Sensory system: vision, hearing, taste, smell

The pH of the saliva, detection of proteins of the saliva. Investigation of saliva amylase and maltase. Demonstration of the protein digesting activity of pepsin. Detection of lactic acid in gastric juice. Collection of gastric juice (MAO, BAO, PAO theory). Measurement of acidity of the gastric juice with titration. Calculate of Body Mass Index (BMI) Video (stomach). Pregnancy tests The effect of insulin on blood glucose level Thorn's test (theory) Demonstration of blood-brain barrier in the rat Human reflexes (patella-, Achilles-tendon, biceps, triceps-, radial-reflex; skin reflexes) Tremor – tremometer. Video (disorders of the motor system) Investigation of the skin senses (pressure, pain, tactile sense, graphaesthesia, sense of localisation). Weber’s 3 basin test. Cool and hot receptors localization on the hand. Observation of the autonomic nervous system with the BIOFEEDBACK program, the polygraph examination (BIOPAC), Vision: determination of visual acuity, accommodation, Mariotte's blind-spot test, the light-response of the pupil(direct and consensual pupil reflex). Testing of colour blindness, visual field. Ophthalmoscopy. Dark adaptation, fusion frequency, observation of the ophtokinetic reflex. Detection of astigmatism (Placido's keratoscope, Javal-Schiötz'-ophthalmometer). Visual evoked potentials (computer program). Optical illusion (magic pictures). Video: visual field Hearing and balance: laryngoscopy, otoscopy Determination of the acoustic acuity (audiometry), tuning fork tests (examinations according to Rinne, Schwabach and Weber). Bárány's pointing test. Sense of taste, olphactometry. Reaction time measurement: motor response to each visual stimulus, and to each auditory

280 Sleep ang higher brain functions

Sport physiology

stimulus (BIOPAC) Effects of relaxation and arousal to body functions. EEG recording. Cognitive tests (Stroop paradigm, Mini-Mental Test, Eyes test, Trail making test). The effects of physical exercise on respiration, heart rate and blood pressure.

COLLOID CHEMISTRY

*

LECTURE Introduction Colloidal state and systems Major characteristics of colloidal systems: classification, definition, delimitation and comparison. Incoherent (incohesive) and coherent (cohesive) colloidal systems. Macromolecular colloids

* *

Chemical structure of macromolecules. Characterization of macromolecular coils.

* *

Preparation of polymeric materials. Macromolecular solutions, molecular mass determination. Polyelectrolytes, structure and solution behavior. Association colloids Structure and types of amphiphilic molecules, HBL scale. Micelle formation equilibrium. Structure of micelle. Critical micelle formation concentration. Physical-chemical properties of surfactant solutions.

* * *

*

* * * * * * * * * * * * * * * * * * * * * * * *

Solubilization in surfactant solutions. Interfaces Interfacial phenomena, interfacial energy. Gas/liquid, liquid/liquid interfaces. Surface tension, surface activity, excess amounts, spreading. Monomolecular films. Gas/solid and liquid/solid interfaces. Adsorption. Adsorbents. Spreading and wetting. Charged interfaces, electric double layer. Electrokinetic phenomena. Preparation, characterization and stability of colloid and coarse disperse systems Classification and characterization of colloid and coarse disperse systems. Spontaneous and forced changes in colloidal state, preparation and destabilization, colloidal stability. Aerosols, foams, emulsions, microemulsions, suspensions and sols. Structural characterization of colloidal systems Particle size and shape. Size distribution. Measuring methods. Coherent systems, gels. Rheology, flow curves, tixotropy.

PRACTICE Safety precaution, fire protection. Viscosity of polymer solutions. Effect of surface active agents on surface tension of water. Solubilization of organic acids. Adsorption from solution, determination of specific surface of adsorbent. Emulsions, microemulsions. Spreading and wetting. Making of monomolecular films by Pockels method.


281

BIOCHEMISTRY * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

Enzymology Definition and scope of biochemistry Conditions of processes in biological systems Living organism as a thermodynamically open system Protein structure Functions of proteins in the organism Protein composition/structure Protein conformation Enzymes Enzymatic action Coenzymes Classification of enzymes. Isoenzymes, their clinical importance Units of enzyme activity Enzyme kinetics Role of enzymes during catalysis Steady state condition Order and conditions of reactions Lineweaver-Burk equation/plot Kinetics of inhibition Carbohydrate metabolism Energy generation and storage Glycolysis Glycogen metabolism Synthesis of glucose (gluconeogenesis) from non-carbohydrate precursosrs: glycerol (from neutral lipids), glucogenic amino acids Importance of hexose monophosphate shunt Relationship between the carbohydrate metabolism and other metabolisms Lipidmetabolism Metabolism of fatty acids and triacyl glycerols and phospholipids Lipoproteins Amino acid metabolism Urea cycle and nitrogen elimination Nucleotide metabolism Citric acid cycle, terminal oxidation and oxidative phosphorylation Citric acid cycle as the central pool of the intermediate metabolism Definition of terminal oxidation, redox systems in the organism Oxidative phosphorylation Biochemical characterization of the connective tissue and the cytoskeleton Collagen structure and its synthesis Biochemistry of membranes Structure of biological membranes, fluid mosaic model Membrane proteins and transport systems Biochemistry of contractile tissues Types of contractile tissues Regulation of muscle contraction by calcium Biochemistry of the neural tissue and vision Biochemistry of the blood Organic components of the blood plasma Biochemical characteristics of blood cells Biochemistry of blood clotting and fibrinolysis Biochemistry of the liver and biotransformation Structure of liver and its microcirculation system

282 * * * * * * * * * * * * * *

Biotransformation Biochemical effects of alcohols Biochemistry of hormones Chemical and biochemical classification of hormones Biochemistry of thyroid and parathyroid hormones Hormonal regulation of blood glucose level Biochemistry of steroid hormones Tissue hormones, growth factors Regulation of gene expression General principles of biochemical regulation, adaptation, limits of adaptation Signalling systems Cyclic nucleotide dependent signalling systems Phosphorylation and dephosphorylation as regulation mechanisms General principles of biochemical regulation

PHARMACEUTICAL BOTANY 4th semester LECTURE (3 hrs/week)


*

Introduction to the course and the living cell. The Introduction, Use of the microscope, Lab drawing, hierarchy of plant structure. Endomembrane concept The living plant cell, plasmolysis and cytoplasm. Nucleus, mitochondria and plastids.

*

Cell wall, plasmodesmata. Meristem & the primary plant body. Plant tissues, simple tissues, tissue systems. Parenchyma and collenchyma

Dermal Tissue System Epiderm cells and stomatal apparatus, Trichomes, Periderm and lenticel

*

Sclerenchyma - Sclereids and fibers. Secretory structures (internal and external sttructures). Dermal Tissue System: Epidermis and stomata, trichomes. Periderm, lenticell

*

Xylem - Tracheids, vessel members, fibers. Primary Vascular Tissue System Xylem, Phloem, Vascular xylem and ontogenesis. Phloem - Sieve tubes and bundles. cells Sieve tubes and cells Ontogenesis and function

*

Root - Primary structure and differentiation. Secondary growth in roots Adventious roots

Tissues of a Monocot Root, Tissues of a Young Dicot Root, Secondary Thickened Roots

*

Shoot apical meristem. Stems and Buds. Stem Primary vascular differentiation. Stem Differentiation and secondary growth.

Anatomy of Secondary Thickened Roots II

*

Woody stem. Cork and anomalous cambia. Stem types and stem modifications. Underground stems. Duration, Plant habit, Leaf structure and ontogeny, Leaf variation

Lab Test

*

Leaf arrangement, Leaf types, Morphology: leaf shapes, margins, venation, Modified structures. Flower structure, Corolla types, Stamens, Pistils, Ovary position, Floral formulas

Primary Growth of Stems, Herbaceous Stems, Woody Stems, Bark

*

Inflorescence types, Sporogenesis and Underground stems gametogenesis, Fertilization and embryogenesis. Pollination, Breeding Systems, Seed, Fruit (dry fruits, fleshy fruits) and seedlings

*

Plant Taxonomy, Nomenclature, Cronquist System, Monocots vs. Dicots. Magnoliidae: Magnoliaceae, Lauraceae, Nymphaeaceae, Ranunculaceae,

Ground Tissue System: Parenchyma Collenchyma Sclerenchyma, Secretory canals and glands

Anatomy of Leaves


283

Papaveraceae *

Hamamelidae: Cannabaceae, Urticaceae,

Anatomy of Seeds

Juglandaceae, Fagaceae, Betulaceae. Caryophyllidae: Phytolaccaceae, Caryophyllaceae, Polygonaceae. *

Rosidae: Rosaceae, Mimosaceae, Caesalpiniaceae, Lab Test Fabaceae, Rutaceae Dilleniidae: Malvaceae, Violaceae, Passifloraceae, Cucurbitaceae, Salicaceae, Brassicaceae

*

Rosidae: Apiaceae, Asteridae: Solanaceae, Lamiaceae, Scrophulariaceae, Rubiaceae Asteridae: Asteraceae, Commelinidae: Poaceae, Liliidae: Liliaceae

Excursion to the Botanic Garden

PHARMACEUTICAL PROPEDEUTICS 4th semester

* * * * * * * * * * * * * * * *

LECTURE (2 hrs/week) Definition of drugs, classification of drugs. Active substances, additives, pharmaceutical dosage forms. Medical prescription. Parts of prescription. Legal condition system of prescription writing. Types of drug prescription: formula magistralis, formula normalis, formula originalis, formula nosocomialis, formula officinalis Pharmacies. Types of pharmacies (public pharmacy, branch pharmacy, ’hand’ pharmacy, hospital pharmacy). Establishment of pharmacies, equipment and fittings in pharmacies, function of pharmacies. Order of service of pharmacies. Instruments and tools in public pharmacies. Functions and structures of pharmacopoeias. Hungarian Pharmacopoeia Ed. VII. and VIII., European Pharmacopoeia. Pharmaceutical collections, specialist books Pharmaceutical calculation (solubility, calculation of concentration, etc.) Role and rules of dose checking. Grouping of dosage forms (liquid, semisolid and solid dosage forms). Classification of dosage forms according to application place. ATC code. Institutional pharmacy and its tasks (hospital and clinical pharmacy). Industrial pharmacy. Mass measurement. General rules of mass measurement. Principles of measurement with scales. Definition and process of filtering. Grouping of procedures according to the energy used. Pharmacist education, graduate and postgraduate education, PhD. Hungarian organizations of pharmacy (Hungarian Society for Pharmaceutical Sciences, Hungarian Chamber of Pharmacists, National Association of Private Pharmacists, etc.). Most important international organizations of pharmacy (FIP, EUFEPS).

HUNGARIAN LANGUAGE 3rd semester

* *

* * * * * *

PRACTICE (4 hrs/week) General revision. A weekend trip to Budapest. The comparative and superlative form of adjectives. Travelling by train. Sightseeing. Travelling abroad:revision of case endings and postpositions. Noun formation. I feel ill 'kell'+personalised infinitive. Reflexive pronouns. Health vocabulary. At the doctor's: kell, lehet, szabad, tilos. Suffix szor/szer/ször. Body parts. Revision TEST 1 Where were you in the summer: past tense conjugations.

284 * * * * * *

What happened? :past tense definite and indefinite. Time expressions. Revision of grammar and vocabulary. Revision of grammar and vocabulary. TEST 2 Preparation for the oral exam Oral tests

4th semester

* * * * * * * * * * * * * *

PRACTICE (4 hrs/week) Services: possesive suffixes in the plural. At the pharmacy. Private conversations:personal pronouns with case endings. Hat/het. Revision of past and present tense conjugation. Questions and question words. Word order and complex sentences. Grammar exercises and reading comprehension tasks. TEST 1 Practising role-play and picture description. Practising role-play and picture description. Grammar exercises and reading comprehension tasks. Grammar exercises and reading comprehension tasks. Words originating from the same root (kezd, kezdıdik etc.) Revision of grammar and vocabulary. Practising role-play and picture description.


285 SYLLABUS FOR 3RD YEAR PHARMACY STUDENTS

PHARMACOGNOSY 5th semester

*

* *

*

*

* *

*

*

* * *

* *

* *

LECTURE PRACTICE (3 hrs/week) (4 hrs/week) About pharmacognosy in general. The history of Receipt of laboratory tools pharmacognosy. Plant nomenclature and nomenclature of plant drugs. What is a plant drug? Collection and cultivation of medicinal plants. About plant drugs. The preparation of plant drugs. Safety and laboratory procedures Basic phytochemistry procedures, extraction methods, chromatography I.: Percolation of Rutae herba with solvents of different polarity, TLC examination of the extracts Basic metabolic pathways. Primary metabolits. The Basic phytochemistry procedures, extraction methods, origin of carbohydrates. The formation of fats and chromatography II.: Separation with column proteins. Secondary metabolites. The origin of chromatography: chloroformic extract of Rutae herba, terpenoids. The formation of phenolic compounds TLC examination of the fractions and alkaloids. About carbohydrates in general. The types, Basic phytochemistry procedures, extraction methods, occurence, uses (in medicine) of carbohydrates. chromatography III.: Isolation of rutamarin with Honey, Tamarin pulp, manna, fig. Rose fruits. preparative TLC, Purity examination of the isolated Starches. component by TLC Two dimensional TLC Gums and mucillages. Tragacantha, acacia gum, Drugs with carbohydrate content I.: Testing of starch agar, cotton. Carragen, steraculia gum, psillium, containing drugs (Maydis amylum, Solani amylum, marshmallow root, linseed. Tritici amylum), Microscopical characteristics, General starch tests, Test for impuritites, Gossypii lana: Behrens, Schweitzer test, Isolation of polysaccharides from Lini semen and Althaeae radix Fats, fixed oils, waxes. Arachis oil, sesame oil, olive Drugs with carbohydrate content II.: Hydrolysis and oil. Castor oil, coconut oil, linseed oil, theobroma TLC determination of the monosaccharides isolated oil. Hydnocarpus oil, bees wax, spermaceti. from the polysaccharides of Lini semen and Althaeae radix, Acaciae gummi, Tragacantha: Test for identification and purity, Determination of swelling value of Agar Prostaglandins. Krebs cycle. Amino acids. Peptides. Drugs with fixed oil content: Comparison of fixed oils Enzymes, pepsin. derived from different drugs with TLC, Test for rancidity, Detection of vitamine A from cod fish liver oil Drugs with organic acid content: Detection of vitamine C from Rosae pseudo-fructus Alkaloids in general. MTO Ornithine-derived alkaloids. Tropane alkaloids. Drugs with alkaloid content I.: General alkaloid Hyoscyamus leaf. Egyptian Henbane. Belladonna reactions, Drugs with alkaloids derived from ornitine: herb and root. Stramonium leaf. Duboisia leaves. alkaloids with tropane skeleton., TLC determination of Coca leaf and Cocaine. Belladonnae folium, Stramonii folium, Hyoscyami folium, Vitali reaction, Detection of scopoletin, Drugs with alkaloids of phenylalanine-origin: Ipecacuanhae radix → Rubremetin-reaction, Frohde-reaction Lysine-derived alkaloids. Lobelia. Tobacco Drugs with alkaloid content II. alkaloids. Drugs with alkaloids derived from phenylalanine: Detection of carotinoids from Capsici fructus, Marquis reaction, detection of meconic acid from Opium Separation of morphine from the other opium alkaloids, Purity test of the isolated morphine by TLC Phenylalanine-derived alkaloids. Opium poppy. Drugs with alkaloid content III.

286 Opium. *

* *

Phenylalanine-derived alkaloids. Ephedra.Khat. Hydrastis. Ipecacuanha. Colchicum seed and Corm.

*

* *

Triptophan-derived alkaloids. Ergot.

*

Calabar bean. Nux vomica. Rauwolfia. Catharanthus roseus. Cinchona. Imidazole alkaloids. Jaborandi leaf. Purine alkaloids. Coffee seed. Thea. Cocoa seed. Mat leaf. Cola. Guarana.

*

Drugs with alkaloids derived from tryptophane: Strychni semen: detection of strychnine, brucine, loganin, Chinchonae cortex: Thalleioquin reaction, Grahe test Secale cornutum: van Urk reaction, detection of antraquinones (sclereritin) Drugs with alkaloid content IV. Drugs with alkaloids derived from tryptophane: Chinchonae cortex: Thalleioquin reaction, Grahe test, Quantitative determination of the alkaloid content of Chinchonae cortex by spectrofotometry Drugs with alkaloid content V. Drugs with alkaloids derive from xanthine: TLC examination of the caffeine, theobromine, theophylline content of Coffeae semen, Colae semen, Cacao semen, Theae folium, Micromurexid reaction MTO

Oral exam: images of medical herbs and in toto drugs

6th semester

*

* * *

*

*

*

*

*

*

LECTURE PRACTICE (3 hrs/week) (4 hrs/week) Isoprenoid compounds (in general, biogenesis). Receipt of laboratory tools Monoterpenes, volatile oil (preparation, characters, uses) Peppermint leaf and oil, spermint oil. Lavender oil and flower. Rosemary oil and leaves. Oil of rose. Safety and laboratory procedures Determination of drugs with volatile oil content I. General examination of volatile oils (colour, odour, taste, purity), Lavandulae flos, Coriandri fructus, Menthae piperitae folium, Menthae crispae folium, Carvi fructus: TLC determination of monoterpenes Caraway and caraway oil. Coriander and coriander Determination of drugs with volatile oil content II. oil. Dill and dill oil. Thyme, eucalyptus oil and leaves. Cardamon fruit, bitter orange peel. Lemon peel, juniper berries and oil. TLC examination of Matricariae flos, Determination of proazulenes by EP-test (Absinthii herba, Millefolii herba, Matricariae flos), Equipment for the steam distillation of the volatile oils Aniseed and aniseed oil, fennel, cinnamon and Determination of drugs with volatile oil content III. cinnamon oil. Star anis fruit and oil. Camphor. Clove and clove oil. Nutmeg and nutmeg oil. Calamus, ginger, turmeric. Iridoids, gentian roots. Valerian. Caryophylli floris aetheroleum: determination of the eugenol content in Cassia flask, Cinnamomi cassiae aetheroleum: determination of the cinnamaldehyde content in Cassia flask, Anisi fructus and Foeniculi dulcis fructus: TLC determination of phenylpropanederivatives Drugs with miscellaneous terpene content: Determination of valepotriates, Definition of bitterness value Determination of unknown drug powders


* *

*

*

*

*

*

* *

*

* *

287 Drugs with saponin content: Liebermann-Burchardreaction (Primulae radix, Saponariae albae radix), TLC determination of Liquiritiae radix, TLC determination of Hederae folium Determination of unknown drug powders Diterpenoids, colophony resin and turpenine. Drugs with digitalis glycoside content: Keller-Kiliani test, Asafoetida, myrrh, Triterpenoids (biogenesis of Baljet test, Kedde test (Digitalis purpureae folium, triterpenoids). Ginseng, senega root. Quillaya bark, Digitalis lanatae folium, Strophanthi semen), TLC Liquorice. determination of Digitalis purpureae, Determination of unknown drug powders About steroids in general (biogenesis of steroids). Drugs with triterpene saponin content I.: TLC Steroidal saponins (dioscorea, solanum, determination of Calendulae flos, TLC determination of sarsaparilla root). Natural steroids as staring Hippocasteni semen, TLC determination of Urticae materials for partial synthesis of pharmaceuticals. herba et radix, Determination of unknown drug powders About cardioactive glycosides containing drugs in MTO general. Digitalis (purpurea) leaf. Digitalis lanata leaf. Strophamtus and other (nerium, thevetia, Drugs with anthraquinone content: Gel convallaria, adonis) cardenolid containing drugs. chromatographic separation and TLC determination of Bufadienolids and its drugs (squills, black hellebore the anthraquinone derivatives of Frangulae cortex, rhizom). Bornträger reaction (Frangulae cortex, Rhei rhizome, Sennae folium, Aloe), Separation of the free and glycosidic antranoids of Aloe and Sennae folium, Rosenthaler and Schouteten test (Aloe) Phenols and phenolic glycosides. PhloroglucinolDrugs with flavonoid content I.: TLC determination of derivatives. Male fern. the flavonoid aglycones (glycoside-free components) from Tiliae flos, TLC determination of the flavonoids from Sambuci flos and Hyperici herba, Determination of unknown drug powders Anthraquinones and glycosides. Senna leaf. Drugs with flavonoid content II.: Isolation and TLC Cascara bark. Frangula bark. Rhubarb. Aloes. determination of the purity of hesperidin from Aurantii epi- and mesocarpium, Detection of procyanidins from Crataegi folium cum flore and Crataegi fructus (BateSmith test), Determination of unknown drug powders Flavonoid compounds. Silybum. Sambucus. Drugs with tannin content: General tannin reactions Drug with hydroquinone derivative content: TLC determination of the methanolic extract and sublimate of Uvae ursi folium, Determination of catechin derivatives and phenolic components of Uvae ursi folium, Determination of unknown drug powders Tannins. Galls and tannic acid. Hamamelis. Drug with triterpene saponin content II.: TLC Catechu. Rhatany. determination of the ginsenosides (A-I) from Panax ginseng tea, capsule and alcoholic extract, Determination of unknown drug powders Coumarins and their glycosides. Visnaga. Lignans. MTO Podophyllum and Podophyllum resin. Simple phenolic compounds. Vanilla and Vanillin. Oral exam: images of medical herbs and in toto drugs Baerberry leaves. Capsicum. Indian hemp. Henna. Sesquiterpenes, chamomile flowers. Matricaria flowers. Fish berries, santonica flowers. Sandal wood, oil of cade.

PHARMACEUTICAL CHEMISTRY 5th semester LECTURE GENERAL PART

*

Definition and classification of drugs or pharmaceuticals. The history and development of drug control. Nomenclature of drugs. Physical, physico-chemical and chemical investigations of

PRACTICE Seminar: Taking laboratory equipment. Measures in the laboratory. Safety instructions and fire-protective rules. Lab note book. Natrii chloridum It. A, B, Pt. Appearance of solution, Acidity or alkalinity, Ferrocyanides, Iodides, Phosphates, Sulphates, Arsenic, Barium, Iron, Heavy metals, Informative test: 2, 3

288 pharmaceuticals and substances used in pharmacy. Identification and qualitative tests, quantitative assays.

INORGANIC PART

*

Halogen group. Chlorine water, Iodine, Hydrochloric acid, Sodium fluoride, Sodium chloride, Potassium chloride, Sodium bromide, Potassium bromide, Sodium iodide, Potassium iodide, Potassium chlorate, Potassium perchlorate.

*

Oxygen compounds. Demineralized water, Distilled water, Hydrogen peroxide solution 30%, Potassium hydroxide, Sodium hydroxide. Sulphur and its compounds. Purified sulphur powder, Precipitated sulphur, Sodium disulphite, Potassium sulphate, Sodium sulphate, Sodium thiosulphate. Nitrogen group. Nitrogen, Concentrated ammonia solution, Ammonium chloride, Ammonium bromide, Nitrous oxide, Sodium nitrite, Concentrated nitric acid, Potassium nitrate.

*

*

*

* *

*

*

Phosphoric acid and its salts. Sodium dihydrogenphosphate, Disodium hydrogenphosphate, Calcium hydrogenphosphate, Tricalcium phosphate. Compounds of arsenic, antimony and bismuth. Arsenic oxide, Bismuth oxynitrate. Carbon group. Activated charcoal, Carbon dioxide, Lithium carbonate, Sodium carbonate, Potassium carbonate, Potassium thiocyanate. Silicon compounds. Hydrophilic colloidal silica, Hydrophobic colloidal silica, Talc, Magnesium trisilicate, White clay. Lead compounds. Lead monoxide, Lead acetate.

Seminar: Reagents, limit test solutions and colorimetric matching fluids. Identifying and general purity tests of European Pharmacopoeia 6th Ed. Ammonii chloridum It. A, B, Pt. Appearance of solution, Acidity or alkalinity, Bromides and iodides, Calcium, Assay, Informative test: 2,3 Kalii chloridum It. A, B, Pt. Appearance of solution, Acidity or alkalinity, Iodides, Sulphates, Barium, Heavy metals, Iron, Informative test: 2,3 Seminar: Pharmaceutical nomenclature. Quantitative assays. Group of halides. Compounds of halides, oxygen group and alkali hydroxids: Chlorine water, bromine, Iodum, Acidum hydrochloridum, Natrii chloridum, Kalii chloridum, Natrii bromidum, Kalii bromidum, Natrii iodidum, Kalii iodidum, chloride of lime, Kalii perchloras, Oxygenium, Aqua purificata, Aqua valde purificata, Aqua ad iniectabilia, Hydrogenii peroxidum 30 per centum, Natrii hydroxydum, Kalii

hydroxidum. Natrii iodidum It. A, B, Pt. Appearance of solution, Alkalinity, Iodates, Sulphates, Thiosulphates, Heavy metals, Iron, Informative test: 1, 3 Iodum It. A, B, Pt.. Bromides, chlorides

Seminar: Sulphur and sulphur compounds. Compounds of the nitrogen group, salts of the phosphoric acid. Sulfur ad usum externum, Natrii metabisulfis, Natrii sulfis, Natrii sulfas, Kalii sulfas, Natrii thiosulfas, Nitrogenium, Ammoniae solutio concentrata, Ammonii chloridum, Ammonii bromidum, Dinitrogenii oxidum, Natrii nitris, Kalii nitras, Natrii dihydrogenophosphas, Kalii dihydrogenophosphas, Dinatrii phosphas, Dikalii phosphas, Calcii hydrogenophosphas, Tricalcii

phosphas. Aqua purificata Pt. Nitrates, Acidity or alkalinity, Oxidisable substances, Chlorides, Sulphates, Ammonium, Calcium and magnesium

Hydrogenii peroxidum 3 per centum It. A, B) Natrii bromidum It. A, B, Pt. Chlorides, Assay, Informative test: 1, 3 Kalii bromidum It. A, B, Pt. Appearance of solution, Acidity or alkalinity, Bromates, Iodides, Sulphates, Heavy metals, Iron, Informative test: 2, 3 Ammonii bromidum It. A, B, Pt. Appearance of solution, Acidity or alkalinity, Bromates, Iodides, Informative test: 2, 3


*

*

*

*

*

* *

*

*

* *

Boron compounds. Boric acid, Sodium borate.

Aluminium compounds. Dried aluminium hydroxide, Aluminium sulphate, Crystalline potassium aluminium sulphate, Aluminium chloride. Zinc compounds. Zinc chloride, Zinc oxide, Zinc sulphate.

289 Seminar: Inorganic arsenic and bismuth compounds. Carbo and inorganic compounds of carbon. Silicium, lead, boron, aluminium and zinc compounds. Arsenii trioxidum ad praeparationes homoeopathicae, Bismuthi subcarbonas, Bismuthi subnitras ponderosus, Carbo activatus, Carbonei dioxidum, Natrii hydrogenocarbonas, Kalii hydrogenocarbonas, Natrii carbonas, Kalii carbonas, Lithii carbonas, Silica

colloidalis anhydrica, Silica colloidalis hydrica, Aluminii magnesii silicas, Magnesii trisilicas, Talcum, Kaolinum ponderosum, Bentonitum, Acidum boricum, Borax, Aluminii oxidum hydricum, Aluminii sulfas, Alumen, Aluminii chloridum, Zinci chloridum, Zinci oxidum, Zinci sulfas. Natrii hydrogenocarbonas It. A, B, C, Pt. Appearance of solution, Carbonate, Chlorides, Sulphates, Heavy metals, Iron, Ammonium, Arsenic, Calcium

Natrii carbonas decahydricus It. A, B, C, Pt. Appearance of solution, Alkali hydroxides and bicarbonates, Informative test: 1, 2 Kalii hydrogenocarbonas It. A, B

Mercury and its compounds. Mercury, Mercury(I) chloride, Mercury(II) amidochloride, Red mercury iodide, Yellow mercury(II) oxide, Mercury(II) sulphide. Copper and silver compounds. Copper(II) sulphate, Seminar: Mercury compounds, iron and iron Silver nitrate. compounds, mangan, calcium, magnesium and barium compounds, mercury, mercury(I) chloride, Hydrargyri dichloridum, Cupri sulfas, Argenti nitras, Ferrum ad praeparationes homoeopathicas, Ferrosi sulfas, Ferri chloridum, Mangani sulfas, Kalii permanganas, Calcii chloridum, Calcii carbonas, Calcii hydroxidum, Calcii sulfas, Magnesii subcarbonas levis, Magnesii chloridum,

Iron and its compounds. Powdered iron, Reduced iron, Iron(III) chloride, Iron(II) sulphate.

Magnesii oxidum leve, Magnesii peroxidum, Magnesii sulfas, Barii sulfas. Natrii thiosulfas It. A, B, C, D, Pt. Appearance of

solution, Acidity or alkalinity, Sulphates and sulphites, Sulphides, Heavy metals, Assay, Informative test: 1, 3 Manganese compounds. Potassium permanganate. Natrii metabisulfis It. B, C, Pt. Appearance of solution, Thiosulphates, Informative test: 1 Calcium compounds. Calcium chloride, Calcium Kalii sulfas It. A, B bromide, Calcium oxide, Dried calcium sulphate, Calcium carbonate. Magnesium compounds. Magnesium chloride, Natrii sulfas decahydricus It. A, B, Pt. Appearance of Magnesium carbonate, Magnesium oxide, solution, Acidity or alkalinity, Chlorides, Calcium, Heavy Magnesium sulphate. metals, Iron, Magnesium, Informative test: 1, 3 Barium compounds. Barium sulphate. Calcii sulfas dihydricus It. B, C Acidum boricum It. A, B, Pt. Organic matter, Assay ORGANIC PART Borax It. A, B, C, Pt. Appearance of solution, pH, Ammonium, Arsenic, Calcium, Heavy metals, Informative test: 1 Natrii nitris It. A, B, Informative test: 1, 3 General Anaesthetics Kalii nitras It. A, B, Informative test: 2, 3 Ether, Chloroform, Halothane (Narcotan), Isofluran Sulfur ad usum externum It. A, B, Pt. Appearance of (Florane), Thiopental (Trapanal) solution, Odour, Acidity or alkalinity, Chlorides, Sulphates, Sulphides

290 *

*

* * *

*

* *

*

*

* *

* *

* *

* *

Sedative-Hypnotics

Seminar: Nomenclature of organic drug compounds. Carbocyclic and heterocyclic skeletons, functional groups. Isomerism of the organic drug compounds. Constitution, configuration, conformation. Geometrical isomerism: Z, E, cis, trans, endo, exo. Chirality, optical isomerism. Enantiomers, epimers, diastereomers, inversion, retention,, enantiomer excess, „euthomer”, „distomer”, ,,eudismic ratio”. Indication of the configuration: Fischer and Cahn-Ingold-Prelog conventions. Absolute and relative configuration. L, D, meso and erithro–threo isomerism, enol–oxo, lactam– lactim tautomerism. Carbo activatus It. A, B, Pt. Acidity or alkalinity, Alkalisoluble coloured substances, Sulphides, Adsorption power, Informative test: 2

Chloral hydrate, Paraldehyde, Carbromal, Barbital, Phenobarbital, Hexobarbital, Glutethimide, Talidomide (Contergan), Nitrazepam (Eunoctin), Midazolam (Dormicum) Drugs Used in the Treatment of Chronic Alcoholism Arsenii trioxidum ad praeparationes homoeopathicas It. A, B Disulfirame (Antaethyl) Dinatrii phosphas dodecahydricus It. A, B, C, D, Informative test: 1, 3 Anticonvulsant Drugs Natrii dihydrogenophosphas dihydricus It. A, B, C, Pt. Appearance of solution, Reducing substances, Informative test: 2, 3 Phenobarbital (Sevenal), Primidone (Sertan), Calcii hydrogenophosphas dihydricus It. A, B, Pt. Phenytoin (Diphedan), Ethosuximide(Petnidan), Carbonates, Chlorides, Sulphates, Arsenic, Barium, Iron, Clonazepam (Rivotril), Carbamazepin (Stazepine, Heavy metals, Informative test: 1, 3 Tegretol), Lamotrigin (Lamictal), Valproic acid (Convulex) Antipsychotics, Neuroleptics Silica colloidalis hydrica It. A, Informative test: 1, 2, 3 Chlorpromazine (Hibernal), Chlorprotixene Seminar: Heterocyclic ringsystems, pharmaceutical (Truxal), Haloperidol, Risperidon (Risperdal), periodicals and manuals, literature. Study of the Clozapine (Leponex), Olanzapin (Zyprexa) pharmaceutical literature by traditional methods and computer. Anxiolytics General anaesthetics: Aether[1], Chloroformium, Halothanum (Narcotan), isoflurane (Forane), thiopental (Trapanal) Chlordiazepoxide (Elenium), Diazepam (Seduxen), Sedatohypnotics: Chloralhydratum, paraldehyde, Medazepam (Rudotel), Alprazolam (Xanax), Carbromalum, Barbitalum, Phenobarbitalum (Sevenal), Tofisopam (Grandaxin), Meprobamate (Andaxin), Hexobarbitalum (Novopan), Glutethimidum (Noxyron), Buspiron (Anxiron), Trimetozine (Trioxazin) thalidomid (Contergan), Nitrazepamum (Eunoctin), Midazolamum (Dormicum) Narcotic Analgesics and their Antagonists Treatment of alcoholism: Disulfiramum (Antaethyl) Morphine, Ethylmorphine, Pethidine (Dolargan), Ferrum ad praeparationes homoeopathicae It. A, Pt. Methadone(Depridol), Fentanyl (Durogesic), Sulphides and phosphides, Assay Tramadol (Contramal), Naloxon (Narcanti) Antidepressants Ferri chloridum hexahydricum It. A, B, Pt. Free chlorine, Ferrous ions, Informative test: 1 Imipramine (Melipramin), Amitriptyline (Teperin), Ferrosi sulfas heptahydricus It. A, B Maprotilin (Ludiomil), Fluoxetin (Prozac), Sertraline (Zoloft) Antiparkinson Agents Magnesii sulfas heptahydricus It. A, B Levodopa, Carbidopa, Amantadine (Viregyt-K), Magnesii subcarbonas levis It. A, B, C, Pt. Appearance Selegiline (Jumex), Procyclidine (Kemadrin), of solution, Chlorides, Sulphates, Arsenic, Calcium, Iron, Apomorphine (Apo Go) Informative test: 1 Muscle Relactants Seminar: Pipecuronium bromide (Arduan), Baclofen Antiepileptics: Phenobarbitalum (Sevenal), Primidonum (Lioresal), Carisoprodol, Tolperisone (Mydeton) (Sertan), Phenytoinum (Diphedan), etosuximid (Petnidan), clonazepam (Rivotril), carbamazepine (Stazepine, Tegretol), lamotrigin (Lamictal), valproic acid (Convulex)


Psychomotor Stimulants, Anorectics

*

Amphetamine, Caffeine

* *

Hallucinogens and illegal drugs Cocain, Heroin, LSD, tetrahydrokannabinol (THC), MDMA (Extasy) Anorectics Sibutramin (Reductil)

* *

*

Nootropics

* * *

*

Piracetam (Nootropil) Parasympathomimetics Acetylcholine, Carbachol (Miostat), Pilocarpine (Humacarpin), Physostigmine, Neostigmine methylsulphate (Stigmosan) Cholinesterase reactivators

*

Pralidoxime

*

Sympathomimetics

*

Epinephrine (Anapen), Isoprenaline, Oxedrine (Sympathomim), Phenylephrine (Vibrocil), Ephedrine (Epherit), Naphazoline, Xylomethazoline (Novorin)

291 Neuroleptics: Chlorpromazini hydrochloricum (Hibernal), chlorprotixen (Truxal), Haloperidolum, Risperidonum (Risperdal), Clozapinum (Leponex), olanzapin (Zyprexa) Anxiolytics: Chlordiazepoxidum (Librium), Diazepamum (Valium), medazepam (Rudotel), alprazolam (Xanax), tofizopam (Grandaxin), meprobamate (Andaxin), buspiron (Anxiron), Trimetozinum (Trioxazin) Kalii permanganas It. A, B, Assay Mangani sulfas monohydricus It. A, B

Magnesii trisilicas It. A, B, Informative test: 1, 2, 3 Magnesii oxidum leve It. A, B, Pt. Appearance of solution, Chlorides, Sulphates, Arsenic, Calcium, Iron, Informative test: 1, 3) Zinci oxidum It. A, B, Pt. Alkalinity, Carbonates and substances insoluble in acids, Assay Zinci sulfas heptahydricus It. A, B Seminar:

Opioid analgesics and antagonists: Morphinium chloratum, Aethylmorphini hydrochloricum, Pethidini hydrochloricum (Dolargan), Methadoni hydrochloricum (Depridol), fentanil (Durogesic), tramadol (Contramal), Naloxone (Narcati) Antidepressants: Imipramini hydrochloricum (Melipramin), Amitriptylini hydrochloricum (Teperin), maprotilin (Ludiomil), fluoxetine (Prozac), sertaline (Zoloft) Antiparkinson agents: levodopa (Dopaflex), carbidopa, amantadine (Viregyt-K), Apomorphini hydrochloricum (Apo-Go), selegiline (Jumex), procyclidine (Kemadrin) Muscle relactants: Pipecuroni hydrobromidum (Arduan), Baclofenum (Lioresal), Carisoprodolum, Tolperisone (Mydeton)

Bismuthi subnitras ponderosus It. A, B, C, Assay, Informative test: 2 Alumen It. A, B, C, Informative test: 1 Aluminii sulfas It. A, B, Pt. Appearance of solution, Ammonium, Iron, Heavy metals, Informative test: Barii sulfas It. A, B, Pt. Oxidisable sulphur compounds, Soluble barium salts Titanii dioxidum It. A, Informative test: 2, 3 Hydrargyri dichloridum It. A, B Argenti nitras It. A, B Cupri sulfas pentahydricus It. A, B, Assay

* * * * * * * * 6th semester

* *

* *

LECTURE Parasympatholytics Atropine, Homatropine, Methylhomatropine bromide, Scopolamine, Propantheline bromide, Tropicamide (Mydrum) Sympatholytics Prazosine (Minipress), Propranolol (Huma-pronol), Atenolol (Blokium), Metoprolol (Betaloc), Pindolol (Visken)

PRACTICE Seminar: Psychomotor stimulants: Amphetamine,[2] Caffeine

Hallucinogens and illegal drugs: Cocaine, heroin, LSD, Tetrahydrocannabinol (THC), MDMA (Ecstasy) Anoretics: Sibutramin (Reductil)

292 * *

* * * * * * * *

*

* * * * * * * * *

* *

*

* * * * * * *

Anti-Migrain Agents Sumatipran (Imigran)

Local anesthetic agents Cocain, benzocain, procain, lidocain, bupivacain (Bucain, Marcain) Spasmolytics Papaverin, Drotaverin (No-Spa), bencyclan (Halidor) Antiasthmatic drugs Theophylline, Salbutamol (Buventol), Terbutaline (Bricanyl) Antiarrhythmic drugs Quinidine, Lidocaine, Amiodarone (Cordarone)

Nootropics: Piracetam (Nootropil) Parasympathomimetics: Acetylcholine, Carbachol (Miostat), Pilocarpine (Humacarpin), Physostigmine, Neoostigmine methylsulphate (Stigmosan) Cholinesterase reactivators: Pralidoxime Trometamolum (Identification: A; Tests: Appearance of solution, pH, Chloride, Heavy metals, Iron; Assay; Informative test: 3) Ureum (Identification: C, D; Tests: Appearance of solution, Alkalinity, Biuret, Ammonium, Heavy metals) Phenolphthaleinum (Identification: B) Vanillinum (Identification: D) Seminar:

Sympathomimetics: Epinephrine (Anapen),

Isoprenaline (Isuprel), Oxedrine (Sympathomim), Phenylephrine, Ephedrine (Epherit), Naphazoline, Xylomethazoline (Novorin) Digitalis and other cardiac glycosides Parasympatholytics: Atropine, Homatropine, Methylhomatropine bromide, Scopolamine, Propantheline bromide, Tropicamide (Mydrum) Digitoxin (Digimerck) Local anesthetic agents: Cocaine, Benzocaine, Procaine, Lidocaine, Bupivacaine (Bucain, Marcain) Xantin derivatives Spasmolytics: Papaverine, Drotaverine (No-Spa), Bencyclane (Halidor) Theobromine, Theophylline, Caffeine Anti-Migrain Agents: Sumatriptan (Imigran) Antiemetics Aether (Tests: Acidity, Substances with a foreign odour, Aldehydes, Peroxides) Ondansetron (Zofran), Dimenhydrinate (Daedalon) Barbitalum (Identification: D; Tests: Acidity; Informative test: 4) Anticoagulants and haemostatics Hexobarbitalum (Identification: D) Acenocoumarol (Syncumar), Ticlopidine (Ticlid) Phenobarbitalum (Identification: D; Tests: Acidity; Informative test: 4) Antihypertensive agents Phenobarbitalum natricum (Identification: D, E; Informative test: 1) Methyldopum (Dopegyt), Captopril (Tensiomin), Natrii acetas trihydricus (Identification: A, B; Tests: Enalapril (Ednyt), Losartan (Cozaar), Dihydralazin Appearance of solution, pH; Reducing substances, (Depressan), Moxonidine (Cynt) Chloride, Sulphate, Arsenic, Heavy metals, Iron; Informative test: 2, 3) Antianginal agents and vasodilators Tosylchloramidum natricum (Identification: A, B, C, D, E; Assay) Glyceril trinitrate (Nitromint), Pentaerythritol Seminar: tetranitrate (Nitropenton), Isosorbide mononitrate (Cardisorb, Rangin), Nicotinic acid, Pentoxyfilline (Trental) Antihyperlipidaemic agents Sympatholytics: Prazosine (Minipress), Propranolol (Huma-pronol), Atenolol (Blokium), Metoprolol (Betaloc), Pindolol (Visken) Lovastatin (Mevacor), Phenofibrate (Lipanthyl, Antiasthmatic drugs: Theophylline, Salbutamol Lipidil) (Buventol), Terbutaline (Bricanyl) Calcium channel blockers Antiarrhythmic drugs: Quinidine, Lidocaine, Amiodarone (Cordarone) Nifedipine (Corinfar), Amlodipin (Amlipin, Norvasc), Digitalis and other cardiac glycosides: Digitoxin Verapamil (Isoptin), Diltiazem (Blocalcin) (Digimerck) Agents improving cerebral circulation Xantin derivatives: Theobromine, Theophylline, Caffeine Vinpocetine (Cavinton), Cinnarizine (Stugeron) Anticoagulants and haemostatics: Acenocoumarol (Syncumar), Ticlopidine (Ticlid) Antitussiv agents Ethanolum (96 per centum) (Identification: C, D; Tests: Appearance, Acidity, alkalinity; Informative test: 2) Codeine, Noscapine, Butamirate (Sinecod), Alcohol isopropylicus (Identification: C; Tests: Prenoxdiazine (Libexin) Peroxides)


Mucolytics

293

Apomorphini hydrochloridum (Identification: C; Informative test: 3, 4)

Codeini hydrochloridum dihydricum (Identification: C,

*

Bromhexine (Paxirasol), Ambroxol (Halixol), Terpin, Acetylcysteine (ACC, Fluimucil) Drugs of osteoporosis prevention

* *

Clodronic acid (Bonefos) Drugs for rheumatic gout

Morphini hydrochloridum (Identification: C, D, E) Calcii gluconas (Identification: B; Tests: Appearance of

* *

Allopurinol (Milurit), Colchidin (Colchicum-Dispert) Thyroid and antithyroid drugs

*

Levothyroxine (Euthyrox), Liothyronin, Thiamazole (Metothyrin), Propylthiouracil (Propycil) Antidiabetics

*

D, E; Informative test: 4)

Ethylmorphini hydrochloridum (Identification: C, D; Informative test: 4)

*

*

*

*

* * * *

* *

*

*

* *

* *

solution, Sucrose and reducing sugars, Chloride; Assay; Informative test: 1, 2, 3) Chlorali hydras (Identification: A, B; Tests: Appearance of solution, pH; Chloral alcoholate, Chloride, Heavy metals; Assay) Seminar:

Antihypertensive agents: Methyldopum (Dopegyt),

Captopril (Tensiomin), Enalapril (Ednyt), Losartan (Cozaar), Dihydralazine (Depressan), Moxonidine (Cynt) Glibenclamide (Gilemal), Metformin (Adimet, Antianginal agents and Vasodilators: Glyceril trinitrate Metrivin) (Nitromint), Pentaerythritol tetranitrate (Nitropenton), Isosorbide mononitrate (Cardisorb, Rangin), Nicotinic acid, Pentoxyfilline (Trental) Artificial sweeteners Antihyperlipidaemic agents: Lovastatin (Mevacor), atorvastatin (Atorvox, Liprimar),Phenofibrate (Lipanthyl, Lipidil) Saccharin sodium, Aspartame (Nutrasweet), Calcium channel blockers: Nifedipine (Corinfar), Acesulfam-potassium amlodipine (Amlipin, Norvasc), Verapamil (Isoptin), Diltiazem (Blocalcin) Mono- and disaccharides Agents improving cerebral circulation: Vinpocetine (Cavinton), Cinnarizine (Stugeron) Fructose, Glucose, Lactose, Sucrose Benzocainum (Identification: C, D; Informative test: 3) Drugs used in stomac disease Cocaini hydrochloridum (Identification: D, E; Informative test: 4) Phenolphthalein, Diphenoxylate (Reasec), Lidocainum (Identification: D, E; Tests: 2,6Loperamide (Imodium), Metoclopramide (Cerucal), dimethylaniline; Informative test: 2) Cimetidine, Ranitidine (Ulceran, Zantac), Omeprazole (Losec), Sulfasalazyneb (Salazopyrin) Diuretics Procaini hydrochloridum (Identification: C, D, E, F; Informative test: 3, 4) Acetazolamide (Huma-Zolamide), Furosemide Tetracaini hydrochloridum (Identification: B, C, D; (Furon), Hydrochlorothiazide (Hypothiazid), Informative test: 2) Etacrynic acid (Uregyt), Amiloride, Spironolactone (Verospiron), Sorbitol Antiallergic antihistamins Acidum asparticum (Identification: B; Tests: Appearance of solution, Chloride, Sulphate; Assay; Informative test: 2, 3) Promethazine (Pipolphen), Dimenhydrinate Glycerolum (85 per centum) (Identification: C, D; (Daedalon), Dimethindene (Fenistil), Cetirizine Assay) (Zyrtec), Loratadine (Claritine) Nonsteroidal analgesics and antipyretics Seminar: Salicyclic acid, Acetylsalicylic acid (Aspirin), Antitussiv agents: Codeine, Noscapine, Butamirate Paracetamol (Rubophen), Phenacetin, Phenazone, (Sinecod), Prenoxdiazine (Libexin) Aminophenazone, Propiphenazone, Metamizol sodium (Algopyrin) Nonsteroidal antiinflammatory agents Mucolytics: Bromhexine (Paxirasol), Ambroxol (Halixol), Terpin, Acetylcysteine (ACC, Fluimucil) Phenylbutazone, Etofenamate (Rheumon), Drugs of osteoporosis prevention: Clodronic acid Nifluminic acid (Donalgin), Indometacin, Diclofenac (Bonefos) (Voltaren, Cataflam), Ibuprofen (Solpaflex, Advil), Naproxen (Naprosyn, Aleve)

294 *

Piroxicam (Hotemin, Feldene),

*

Antiinflammatory steroids

*

Hydrocortisone, Prednisolone, Triamcinolone acetonide (Ftorocort), Flucinolone acetonide (Flucinar), Betamethazone (Diprophos), Dexamethasone (Oradexon), Beclomethasone (Aldecin), Budesonide (Pulmicort), Mazipredone (Depersolon) Antifungal agents

* *

*

Clotrimazole (Canesten), Tolnaftate (Chinofungin), Terbinafine (Lamisil), Ketoconazole (Nizoral), Fluconazole (Diflucan) Drugs used in the chemtoherapy of helminthiasis

Drugs for gout: Allopurinol (Milurit), Colchicine (Colchicum-Dispert) Thyroid and antithyroid drugs: Levothyroxine (Euthyrox), Liothyronin, Thiamazole (Metothyrin), Propylthiouracil (Propycil) Antidiabetics: insulin, Glibenklamide (Gilemal), Metformin (Adimet, Metrivin)

Artificial sweeteners: Saccharin sodium, Aspartame (Nutrasweet), Acesulfame potassium Mono- and disaccharides: Fructose, Glucose, Lactose, Sucrose

Atropini sulfas (Identification: D, E, F; Informative test: 3)

* * * * *

*

Levamisole (Decaris), Mebendazole (Vermox) Antimalarial agents Quinine, Chloroquine (Delagil), Mefloquine (Lariam), Pyrimethamine Antiseptics and desinfectans Methenamine, Ethanol, Isopropanol, Phenol, Thymol, Resorcin, Clioquinol, Hexachlorophene, Benzalkonium chloride, Tosylchloramid sodium, Lactic acid, Chlorohedidine, Acriflavinium chloride, Xanthacridine chloride, Briliant green, Fuchsin, Methylene blue Microbiological preservatives

Physostigmini salicylas (Identification: C, D) Pilocarpini hydrochloridum (Identification: D, E) Ephedrini hydrochloridum (Identification: D, E) Isoprenalini hydrochloridum (Identification: D, E) Papaverini hydrochloridum (Identification: D; Informative test: 2)

Natrii edetas (Identification: B, C, D; Assay; Informative test: 3)

*

Methyl (p-hydroxy benzoate), Benzylalcohol, Benzoic acid, Sorbic acid Chemotherapic sulfonamides

Acidum acetylsalicylicum (Identification: B, C, D; Assay;

*

Sulfadimidine, Sulfamethoxazole

Acidum salicylicum (Identification: C; Informative test:

*

Chemotherapic nitrocompounds

*

Nitrofurantoin, Metronidazole (Klion)

*

Other chemotherapic compounds

*

Trimethoprim, Nalidixic acid (Nevigramon)

* * * *

Fluoroquinolon derivatives Ciprofloxacin (Ciprobay), Ofloxacin (Tarivid) Antituberculotics Isoniazid (Isonicid), Pyrazinamide, Ethambutol (Sural)

*

Sex hormones and analogues

*

Oestradiol, Oestrone, Ethinyl oestradiol, Clomifen (Clostilbegyt), Raloxifen (Evista), Testosterone (Andriol), Nandrolol (Retabolil), Progesterone, Levonorgestrel

*

Formaldehydi solutio (35 per centum) (Identification: A, B, C; Tests: Appearance of solution, Acidity; Assay) Informative test: 1) 2, 3)

Methylis parahydroxybenzoas (Identification: D; Informative test: 2, 3) Phenazonum (Identification: C, D; Tests: Appearance of solution, Acidity, alkalinity, Chloride, Sulphate, Heavy metals; Assay; Informative test: 4) Metamizolum natricum (Identification: B, C, D; Informative test: 1, 3) Phenylbutazonum (Identification: D; Informative test: 1, 2) Paracetamolum (Identification: D, E) Indometacinum (Identification: D, E) Seminar: Drugs used in stomac disease : Phenolphthalein, Diphenoxylate, Loperamide (Imodium), Metoclopramide (Cerucal), Cimetidine (Histodil), Ranitidine (Ulceran, Zantac), Omeprazole (Losec), Sulfasalazine (Salazopyrin) Antiemetics: Ondansetron (Zofran), Dimenhydrinate (Daedalon) Diuretics: Acetazolamide (Huma-Zolamide), Furosemide (Furon), Hydrochlorothiazide (Hypothiazid), Etacrynic acid (Uregyt), Amiloride, Spironolactone (Verospiron), Sorbitol


295

*

Nonsteroidal agents acting on sexual activity

*

Sildenafil (Viagra), Apomorphine (Uprima)

* *

Vitamins Retinol (vitamin A1), Ergocalciferol (vitamin D2), Cholecalciferol (vitamin D3), Menadione (vitamin K3), Thiamine chloride (vitamin B1), Riboflavine (vitamin B2), Pyridoxine (vitamin B6), Nicotinamide, Folic acid, Ascorbic acid (vitamin C) Antiviral agents Thiamini hydrochloridum (Identification: B, C; Informative test: 2) Amantadine, Acyclovir (Zovirax), Ribavirin Cholesterolum (Identification: C; Informative test: 1) (Copegus, Rebetol), Nevirapine (Viramune) Antibiotics Prednisolonum (Informative test: 1) Benzylpenicillin, Ampicillin (Semicillin), Amoxicillin Acidum citricum monohydricum (Identification: A, C, D; (Aktil), Oxacillin, Imipenem (Tienam) Tests: Appearance of solution, Oxalic acid, Sulphate, Heavy metals; Informative test: 3) Sulbactam (Unasyn), Clavulanic acid, Cephalexin Natrii citras (Identification: A, B; Tests: Appearance of (Pyassan), Cefuroxime (Zinacef, Zinnat), solution, Acidity, alkalinity, Chloride, Oxalates, Sulphate, Chloramphenicol, Doxycycline (Tenutan) Heavy metals; Assay; Informative test: 2, 3) Antineoplastic agents Seminar: Cyclophosphamide (Cytoxan), Carmustin (BICNU), Nonsteroidal analgesics and antipyretics: Salicyclic acid, Acetylsalicylic acid (Aspirin), Paracetamol Cisplatin (Platidiam), Carboplatin (Cycloplatin), Fluorouracil (Efudix), Methotrexate (Trexan), (Rubophen), Phenacetin, Aminophenazone, Imatinib (Glivec) Propiphenazone, Metamizol sodium (Algopyrin) Drugs used for immunomodulation Nonsteroidal antiinflammatory agents: Phenylbutazone, Etofenamate (Rheumon), Nifluminic acid (Donalgin), Indometacin, Diclofenac (Voltaren, Cataflam), Ibuprofen (Solpaflex, Advil), Naproxen (Naprosyn, Aleve), Piroxicam (Hotemin, Feldene) Azathioprine (Imuran) Antiinflammatory steroids: Hydrocortisone, Prednisolone, Triamcinolone acetonide (Ftorocort), Flucinolone acetonide (Flucinar), Betamethazone (Diprophos), Dexamethasone (Oradexon), Beclomethasone (Aldecin), Budesonide (Pulmicort), Mazipredone Coffeinum (Identification: C, D, F; Informative test: 3) Theobrominum (Identification: B, C; Tests: Acidity; Informative test: 3) Theophyllinum (Identification: C, E; Tests: Appearance of solution, Acidity; Assay; Informative test: 3) Acidum tartaricum (Identification: A, B; Tests: Appearance of solution, Oxalic acid, Chloride, Sulphate, Calcium) Methenaminum (Identification: B, C, D; Tests: Appearance of solution, Acidity, alkalinity, Free formaldehyde, Chloride, Sulphate, Ammonium, Heavy metals; Informative test: 1) Seminar: Antifungal agents: Clotrimazole (Canesten), Tolnaftate (Chinofungin), Terbinafine (Lamisil), Ketoconazole (Nizoral), Fluconazole (Diflucan) Drugs used in the chemtoherapy of helminthiasis: Levamisole (Decaris), Mebendazole (Vermox) Antimalarial agents: Quinine, Chloroquine (Delagil), Mefloquine (Lariam), Pyrimethamine Antiseptics and desinfectans: Tosylchloramide sodium, Methenamine, Chlorhexidine

* * * *

*

* *

*

*

* * * *

*

* *

* * *

Antiallergic antihistamins: Promethazine (Pipolphen), Dimenhydrinate (Daedalon), Dimethindene (Fenistil), Cetirizine (Zyrtec), Loratadine (Claritine) Acidum ascorbicum (Identification: D; Assay; Informative test: 2) Nicotinamidum (Identification: C, D) Riboflavinum (Identification: C)

296 *

Microbiological preservatives: Methyl phydroxybenzoate

*

Chemotherapic silfonamides: Sulfadimidine,

*

Chemotherapic nitrocompounds: Nitrofurantoin,

Sulfamethoxazole Metronidazole (Klion) *

Other chemotherapic compounds: Trimethoprim, Nalidixic acid (Nevigramon)

Fluoroquinolon derivatives: Ciprofloxacin (Ciprobay), Ofloxacin (Tarivid) *

Antituberculotics: Isoniazid (Isonicid), Pyrazinamide, Ethambutol (Sural)

*

Saccharinum natricum (Identification: C, D, E;

* *

Fructosum (Identification: B, C, D) Glucosum anhydricum (Identification: C; Tests:

Informative test: 1)

* * *

* * * *

*

* * * * * * * *

*

Appearance of solution, Acidity, Alkalinity, Foreign sugars, soluble starch, dextrins, Chloride, Sulphate, Arsenic, Barium, Calcium; Informative test: 2) Lactosum monohydricum (Identification: C; Informative test: 2) Sorbitolum (Tests: Reducing sugars; Informative test: 2) Saccharum (Identification: C; Tests: Appearance of solution, Acidity, Alkalinity, Dextrin, Glucose and invertsugars) Bismuthi subsalicylas (Identification: A, B; Tests: Chloride; Assay; Informative test: 1) Bismuthi subgallas (Identification: A, B) Seminar: Sex hormones and analogues: Oestradiol, Ethinyl oestradiol, Clomifen (Clostilbegyt), raloxifen (Evista), Testosterone (Andriol), Nandrolone (Retabolil), Progesterone, Levonorgestrel Nonsteroidal agents acting on sexual activity : Sildenafil (Viagra), Apomorphine (Uprima) Vitamins: Retinol (vitamin A1), Ergocalciferol (vitamin D2), Cholecalciferol (vitamin D3), Menadione (vitamin K3), Thiamine chloride (vitamin B1), Riboflavine (vitamin B2), Pyridoxine (vitamin B6), Nicotinamide, Folic acid, Ascorbic acid (vitamin C) Phenolum (Identification: A, B, C) Resorcinolum (Identification: B, C; Tests: Appearance of solution, Acidity, alkalinity, Pyrocatechol; Assay) Thymolum (Identification: C, D) Acidum benzoicum (Identification: B; Tests: Oxidisable substances; Assay; Informative test: 1, 2) Natrii benzoas (Identification: A, B; Tests: Appearance of solution, Acidity, Alkalinity; Informative test: 2, 3) Seminar: Antiviral agents: Amantadine, Acyclovir (Zovirax), Ribavirin (Copegus, Rebetol), Nevirapine (Viramune) Antibiotics: Benzylpenicillin, Ampicillin (Semicillin), Amoxicillin (Aktil), Oxacillin, Imipenem (Tienam), Sulbactam, Clavulanic acid, Cephalexin (Pyassan), Cefuroxime (Zinacef, Zinnat), Chloramphenicol, Doxycycline (Tenutan), Neomycin, Erythromycin (Eryc) Antineoplastic agents: Cyclophosphamide (Cytoxan), Cisplatin (Platidiam), Carboplatin (Cycloplatin), Fluorouracil (Efudix), Methotrexate (Trexan), Imatinib (Glivec)


297

Drugs used for immunomodulation: Azathioprine

*

(Imuran)

Chloramphenicolum (Identification: D, E; Informative

*

test: 1)

Oxytetracyclini hydrochloridum (Identification: B, C; Informative test: 2) Sulfadimidinum (Identification: C, D; Informative test: 1) Chinidini sulfas (Identification: B, C; D, E, F; Tests: pH; Informative test: 1, 3, 4) Chinini sulfas (Identification: B, C, D, E; Tests: pH; Informative test: 1, 3, 4) Acidum lacticum (Identification: A, C; Tests: Appearance, Sugars and other reducing substances,, Citric, oxalic and phosphoric acids, Sulphate, Calcium, Heavy metals; Assay; Informative test: 3)

* * * *

PHARMACEUTICAL TECHNOLOGY 5th semester

* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

LECTURE Introduction to Pharmaceutical Technology I, General considerations Pharmaceutics Biopharmaceutics Classification of technological operations Types of dosage forms Quality for pharmaceutical products Introduction to Pharmaceutical Technology II Preformulation, formulation Drug formulation by neural network and factorial design Normatives in pharmaceutical technology GMP, ISO Validation, qualification Basics of industrial drug formulation Physico-chemical basics of pharmaceutical technology, theory and practice Interfacial phenomena Surface and interfacial phenomena Adsorption Adhesion Electrokinetic processes Rheology in pharmaceutical technology Concept of rheology Classification of rheological processes Rheology of disperse and coherent systems Connection between the pharmaceutical technology and the technical chemistry Water purifying methods Distillation Ion exchanging Reverse osmosis Seawater desalination Excipients in pharmaceutical technology Classification of excipients Dosage forms and excipients Liquid dosage forms Grouping Physicochemical characteristics Stability problems Biopharmaceutical considerations Emusions and suspensions

298 * * * * * * * * * * * *

Types and stability Administration routes Excipients Liposomes Types and stability Administration routes Powders Particle size, distribution mixing Extraction of plants Methods and equipment Types

6th semester

* * * * * * * * * *

LECTURE Aerosols and Inhalasols Types and stability Administration routes Preparations Theory and practice of sterilization Theory of sterilization Methods Control of sterilizing Aseptic dosage forms Requirements of parenteral preparations

* * * * * * * *

Clean air technology Application routes Excipients Containers Elements of homeostasis TestS for pyrogens Dosage forms Industrial metods

* * * * * * * * * * * * *

Microbiological preservation of liquid dosage forms Requirements of preservatives Efficacy of preservatives Preservatives Ophthalmic dosage forms Eye drops Eye cleaning solutions Semisolid dosage forms Classification of dermatological preparations Types of ointment bases Production of ointments Investigation of ointments Choice of oinments, therapeutic and practical considerations Gels Polymers in pharmaceutical technology Hydrogels Stimuli responsive hydrogels Nasal drug delivery systems Basic concepts of administration Factors affecting bioavailability Dosage forms and excipients Rectal and vaginal dosage forms

* * * * * * * * *

PRACTICE Prescription pharmacy 1 General instruction Rules of measuring Dispensing of solutions „A” measuring of liquids „B” measuring of powders Writing of prescriptions Liquid dosage forms Solutio Diluendum, aqua aromatica, gargarisma, elixírium, mixtura, sirupus, klysma Solubility, right order of dissolving, dilution, calculation Solvents, excipients) Calculation Solutio acriflavini (FoNo VII. 20,0 g) Solutio contra rhagades mamillae(FoNo VII. 33,6 g) Gargarisma chlorogenii (FoNo VII. 100,0 g) Sirupus zinci (FoNo VII. 100,0 g) Solutio noraminophenazoni pro parvulo (FoNo VII. 100,0 g Mixtura pectoralis (FoNo VII. 100,0 g Solutio pepsini (FoNo VII. 100,0 g Magistral preparation (50,0g) Mixtura solvens (FoNo VII. 100,0 g Gutta, Klysma Checking the dose Otogutta, nasogutta Dilutio, trituration Gutta methylhomatropini composita (FoNo VII. 10,0 g) Otogutta peroxydi (FoNo VII. 10,0 g) Klysma chlorali pro infante (FoNo VII. 80,0 g) Nasogutta zinci cum ephedrino (FoNo VII. 10,0 g) Solutio theophyllini (FoNo VII. 100,0 g) Solutio nephrolitica (FoNo VII. 100,0 g)Incompatibility AUV preparations Oily and alcoholic solutions Incomp II (sol. 150,0g) Otogutta fungicida (FoNo III Vet) Solutio metronidazoli (FoNo VII. 30,0g) Spiritus iododalicylatus (FoNo VII. 30,0g) Self-made preparation Incomp I (gutta 20,0g)

Curriculum 2014/2015 * * * * * * * *

Therapeutic considerations Dosage forms Additives Granulation and granules Types of granules Particle binding mechanisms Methods of granulation Investigation of granules

* *

Pressing of solid particles, compressibility and process Tablet compression

* * * *

Tablet compression machinery Compressibility and its measurement Tablet making and texture of tablets Development of solid dosage forms

*

Methods

*

Excipients

* *

Characteristics of texture Preformulation tests

*

Tests of tablets

*

Influencing factors on the physical parameters

*

Problems during tableting

* * *

Equipment for the tablet making

*

*

* * *

* * *

299 Oleum pro inhalatione (FoNo VII. 20,0g) Gutta antipyretica (FoNo Vet. III. 100,0g) Galenic Practice Introduction Functions of a galenic pharmacy Galenic preparations of the Pharmacopoea Calculations Dosage form investigations of the Pharmacopoea (Ph.Eur., USP, Br.Ph.) Quality control, Operation methods, Production sheets Safety precaution, fire protection, material safety data sheets Measurement of mass, balances Definitions, types, general rules Mechanical balances: mass-comparative balances: equal arm balances (Berkel), unequal-arm balances (OWA, Metripond, cg quick balance); deformation principles balances (coil, spiral and bent spring); Electronical (strain-gauge) balances: advantages, different functions, types (analytical, precision and industrial platform balances, moisture analyser balance), adjusting/calibration (inner, external). Separation methods: Distillation: definition, parts, sets of operation/material/heating, laboratory distillator, thermocompression, products; Ion-exchange/demineralization: theory, synthetic resins, capacity, process, products; Reverse osmosis (RO): theory, RO membrane, process, product; Centrifugation: definition, factors, alignment, parts, types of rotors (e.g. swing-out rotor, angle rotor). Desintegration Crushing, pulverization: definitions, working principle, efficiency of crushing, crushers (Jaw, gyratory) grinders (roller and hammer); Process of milling: mills (mortar and pestle, ball, vibratory ball, centrifugal ball, planetary ball, disk, cutting, industrial jet and colloid mill), rotary cone sample divider; Particle size analysis (PSA) and its application: importance, FDA guide, USP tests, US and UK standard sieves, frequency of distribution, cumulated plots, microscopic measurement, laser diffractometer. Homogenization Mixing: definiton, efficiency, required mixing time, mixing equipments Liquid mixing: paddle, anchor and propeller type, high shear homogenizer, circular flow and turbine mixer, shakers; Mixing of semisolids: planetary mixer, kneaders, dispersers, curved blade impeller; Mixing of solids: cylindric, cubic, tumbler, double cone, twin shell and vertical screw mixers. Material transfers

300 *

Drying: definitions, purpose, efficiency, industrial microwave drying, vacuum drying, spray drying (nozzle, atomizer) and its application; Dissolution: solutions, theory, definitions, expressions of concentration, pharmaceutical applications, dosage form, dissolution rate, formulation; Molecular and colloidal solution (preparation): real solution, stock solution, syrups (medicinal and flavouring), mucilages (polymers), elixirs, spirits, mixtures, aromatic waters, tinctures; Industrial liquid mixing equipments (e.g. double planetary mixer, high-shear rotor-stator mixer, different mixing blades, Powermix and Triple Shaft mixer, disperser), filtering, storage tanks, industrial liquid filling. Extraction and extracts: definiton, types of process and equipments (maceration, turboextraction, vibroextraction, percolation), dosage forms (preparation, requirements, storage): extracts, tinctures. Preparation of disperse systems Emulsifying: emulsions, definitions, types, calculation (work-equation, required HLB), industrial manufacturing methods, equipments (mixers, homogenizers, colloid mills, ultrasonic devices), stability; Suspending: suspenions, definitions, classification, flocculation, industrial manufacturing methods, equipments, kinetics of sedimentation. Semisolid dosage forms Soaps and soap-containing preparations: definitons, types, preparations (Ph.Hg. and USP); Ointments, creams, pastes, hydrogels: definitions, classifications, requirements, types of ointment bases, industrial production of semisolid preparations, laboratory (LUX, Erweka, Sabaria) and industrial mixers (e.g. counter-rotating paddle agitator), pastes, threeroll apparatus, penetrometric examination; Suppositories: definitions, types, types and preparation of suppository bases, laboratory and industrial preparation of suppositories (suppository moulding equpiments), types of moulds (metal, plastic), form-fillseal.

*

*

*

* *

* *

*

* * *

*

PATHOPHYSIOLOGY 5th semester LECTURE

SEMINAR/PRACTICE

Introduction to Pathophysiology; Inflammation I.: Definition, causes, mediators and signs of acute inflammation. Regulation and outcome of acute inflammation.

Safety regulations. Review of physiologic background of circulation and normal ECG. In the practice room: Registration and analysis of ECG. Determination of spirometric parameters.

Inflammation II.: Chronic inflammation. Local and generalized reactions of inflammation: fever, inflammatory pain.

Seminar: Inflammation I. (Lecture topic of the 1st week). In the practice room: Registration and analysis of ECG. Determination of spirometric parameters.

Pathophysiology of leukocytes I.: Immunology: In vivo allergic reactions,

Seminar: Inflammation II. (Lecture topic of the 2nd week).


301

autoimmunity, immunodeficiency. Endocrinology I.: Disturbances of endocrine regulation. Diseases of hypothalamus, hypophysis and thyroid gland. Hyperparathyreoidism.

Seminar: Pathophysiology of leukocytes I.: Immunology (Lecture topic of the 3rd week).

Endocrinology II.: Hypoparathyreoidism. Diseases of adrenal (cortex and medulla) gland.


Starvation and obesity. Diabetes mellitus, hypoglycemia Diabetes mellitus causes, types, clinical signs, pathogenesis and consequences. Hypoglycemia

Seminar: Endocrinology II. (Lecture topic of the 5th week).

Cardiovascular system I.: Pathophysiology of plasma lipoprotein metabolism. Development of atherosclerosis.

Seminar: Starvation and obesity. Disturbances of carbohydrate metabolism (Lecture topic of the 6th week).

Cardiovascular system II.: Seminar: Cardiovascular system I. Pathogenesis and consequences of atherosclerosis. (Lecture topic of the 7thweek). Primary and secondary hypertension. Cardiovascular system III.: Pathophysiology and ECG of acute coronary syndromes: angina pectoris, myocardial infarction

Seminar: Cardiovascular system II. (Lecture topic of the 8th week).

Cardiovascular system IV.: Congenital heart diseases. Mitral, aortic stenosis and regurgitation. Compensated and decompensated heart function, Heart failure.

Seminar: Cardiovascular system III. (Lecture topic of the 9th week).

Peripheral circulatory diseases: Volume depletion. Syncope. Circulatory shock (development, stages). Multiple organ dysfunctions in shock.


Pathophysiology of salt-water balance I.: Volume excess, hyper- and hyponatremia, hyperand hypocalcemia

Seminar: Peripheral circulatory disease (Lecture topic of the 11th week).

Pathophysiology of salt-water balance II.: Hyper- and hypokalemia, disturbances of trace elements and vitamins.

Seminar: Pathophysiology of salt-water balance I (Lecture topic of the 12th week).

Cardiovascular system V.: Disturbances of electrical impulse generation and conduction.

Seminar: Pathophysiology of salt-water balance II (Lecture topic of the 13th week).

6th semester LECTURE Pathophysiology of kidney diseases I.: Proteinuria, hematuria, glycosuria, ketonuria, pyuria, bacteruria, polyuria, oliguria and anuria.

SEMINAR/PRACTICE Safety regulations. Seminar: Thermoregulation. (Please download and study the material from our website or coospace before class).

Pathophysiology of kidney diseases II.: Nephrotic and nephritic syndrome, pyelonephritis, kidney stones. Acute and chronic renal failure.

Seminar: Kidney diseases I. (Lecture topic of the 1st week). In the practice room: Investigation of urine and renal function: proteinuria, hematuria, pyuria, hemoglobinuria, ketone bodies, urobilinogen, urine

302 sediment and casts. Pulmonary diseases I: Abnormal breathing patterns, dyspneas. Obstructive pulmonary diseases: CODP, asthma bronchiale, cystic fibrosis.

Pulmonary diseases II: Restrictive pulmonary diseases (pleural disorders, pulmonary edema, embolism, hypertension), hypoxias, respiratory failure.

Seminar: Kidney diseases II. (Lecture topic of the 2nd week). In the practice room: Investigation of urine and renal function: proteinuria, hematuria, pyuria, hemoglobinuria, ketone bodies, urobilinogen, urine sediment and casts. Seminar: Pathophysiology of pulmonary diseases I. (Lecture topic of the 3rd week).

Disturbances of acid-base metabolism: Respiratory acidosis and alkalosis. Metabolic acidosis and alkalosis.



Seminar: Disturbances of acid-base metabolism (Lecture topic of the 5th week).

Gastrointestinal diseases II.: Diseases of absorption, diarrhea, constipation. Intestinal obstruction. Acute and chronic pancreatitis.

Seminar: Gastroenterology I. (Lecture topic of the 6th week).

Diseases of liver and biliary tract: Diseases of Seminar: Gastroenterology II. (Lecture topic of the 7th bilirubin metabolism: hemolytic, hepatocellular and week). obstructive jaundice. Causes, pathogenesis and consequences of hepatic cirrhosis. Pathophysiology of leukocytes: Leucopenia. Proliferative diseases: reactive and malignant diseases (leukemias, lymphomas).

Seminar: Pathophysiology of liver diseases (Lecture topic of the 8th week).

Red blood cell diseases I.: Polycytemias, Anemias - ineffective erythropoesis.

Seminar: Pathophysiology of leucocytes II. (Lecture topic of the 9th week).

Red blood cell diseases II.: Anemias due to blood loss, hemolysis. Hemostasis I.: Bleeding disorders (platelet disturbances).

Seminar: Red blood cell diseases I. (Lecture topic of the 11th week).

Hemostasis II.: Bleeding disorders (vascular, clotting factor disturbances), thrombosis and embolism.

Seminar: Red blood cell diseases II. Hemostasis I. (Lecture topic of the 12th week). In the practice room: Determination of WBC, RBC, platelet, eosinophyl and reticulocyte count. Staining and analysis of blood smear.

Pathophysiology of the CNS I.: Multiple sclerosis, neurodegenerative diseases: Alzheimer’s, Parkinson’s and Huntington’s disease. Pathogenesis of psychiatric disorders.

Seminar: Hemostasis II. (Lecture topic of the 13th week). In the practice room: Determination of WBC, RBC, platelet, eosinophyl and reticulocyte count. Staining and analysis of blood smear.

Pathophysiology of the CNS II.: Circulatory diseases of the CNS. Cerebral edema. Pain, headaches, seizures and epilepsy.


Curriculum 2014/2015 MICROBIOLOGY AND IMMUNOLOGY 5th semester LECTURE (4hrs/week) * Introduction to microbiology. Classification and characterization of bacteria. Microbial genetics. Basic principles of immunology. Constituents of the immune system. Primary and secondary immune organs. Antigens. * Principles and practice of sterilization and disinfection. Factory hygiene and good manufacturing practice. Microbiological requirements and purity classes of pharmaceutical products. Antigen recognition by and activation of T and B cells. Pharmaceutical products of microbial origin. Microorganisms in pharmaceutical industry. Production of pharmaceuticals by recombinant DNA technology. The histocompatibility complex (MHC). Antigen presentation by MHC. * Antibiotics and antimicrobial agents. Mechanisms of action of antibiotics Bacterial resistance to antibiotics. Antibiotic policy. Industrial production of antibiotics. Humoral immune response. Structure of immunoglobulins * Streptococcus, Neisseria, Enterococcus, Staphylococcus Complement system. * Gram negative rods I. Enteric and extraintestinal pathogens Mycobacterium. * Gram negative rods II. Bacteria related to respiratory tract (Haemophilus, Bordetella, Legionella) Pathogens of zoonoses (Yersinia, Francisella) Gram positive aerob rods (Corynebacterium, Listeria) Cytokines I.

*

Gram positive anaerob rods (Clostridium)B. anthracis Spirohatales. Cytokines II. holiday General properties and structure of viruses. Reproduction of viruses. Viral pathogenesis, chemotherapy of viral infections Obligate intracellular bacteria (Chlamydia, Coxiella bunettii,

*

Mechanisms of immunotolerance. Immunology of transplantation. Autoimmunity Hepatitis viruses DNA viruses. Herpesviruses, human papillomaviruses

303

PRACTICE (2hrs/week) Introduction, laboratory safety. Wet-mount preparation. Preparation of bacterial smear, simple staining.

Combined staining. Practice of sterilization. Sterility testing. Disinfection.

Culture media. Inoculation and plating bacterial culture. Haemoculture. Colony morphology.

Biochemical tests. Anaerobic cultivation.

Test of bacterial resistance to antibiotics. Enumeration of bacteria.

Sterility and pyrogenicity testing of pharmaceutical products Serological tests I.: Precipitation, agglutination.

MTO

holiday Serological tests II.: CFT; IF; RIA, etc. Cell mediated reactions. Serobacteriological products. Vaccines.

R. slovaca, R. prowazekii)

Summary of the most important human pathogenic bacteria I.

304 Hypersensitivity reaction. Immunodeficiencies. *

*

RNA viruses II. Slow viruses. Retroviridae, AIDS RNA viruses I. Influenzaviruses, measles-, mumps-, rubeola viruses. Immunization against microbes. Vaccination RNA viruses III Poliovirus, coxsackie viruses Rabiesvirus. Manufacture of immunological products and their quality control. Fungi of medical importance. Immunological methods. Important human pathogenic helminths. Important human pathogenic protozoa.

Summary of the most important human pathogenic bacteria II.

Propagation and assay of viruses. Serological methods in virology.

Important human pathogenic fungi. Consultation

BIOPHARMACY LECTURE Basic principles

PRACTICE Basic principles, drug administration.

Drug absorption and distribution. Specific distributions, Blood-brain barrier, placenta. Plasma protein binding.

Absorption, distribution. Blood plasma curve of one compartment intravascular model system.

Drug metabolism, first-pass effect, factors influencing metabolism. Drug elimination, clearance. Pharmacokinetics of repeated dose administration, plato phenomenon. Pharmacokinetic model systems. Concept and determination of AUC. Model independent pharmacokinetics. Physiological and Biological availability. Equivalences.

Drug metabolism. Blood plasma curve of one compartment extravascular model system. Pharmacokinetic of Infusion. Blood plasma curve of repeated dose administration. Blood plasma curve of two compartment intravascular model system. Calculation of physiological availability and absolute and relative bioavailability. Multi dose schedule for subject with renal impairment.

Factors influencing biological effects of drugs.

Multi dose schedule for subject with hepatic dysfunction. Dosage schedule for children and elderly subjects.

Dose - response relationships.

Dose-response curves. Calculation of ED50, pD2.

Drug interactions. Synergism, antagonism.

Synergism, antagonism, dose-response curves. Calculation of ED50, pD2, pA2, pD'2.

Receptors, signal transduction. Drug allergy, idiosyncratic drug reactions, polymorphisms.

Non-linear pharmacokinetics, Michaelis-Menten pharmacokinetics.

Therapeutic drug monitoring. Non-linear pharmacokinetics.

HUNGARIAN FOR PHARMACEUTICAL PURPOSES 1st semester PRACTICE (3 hrs/week) * The human body. The main systems and organs. Terminology exercises.


305 Drug forms. Drugs for internal and external use. Definition and translation of new expressions. Drug description analyses: indication, dosage, contraindication. Comparison of Hungarian and English drug description. Administration of drugs. The effect of drugs. Drug interaction. Side effects of medications. Word building exercises. Classification of drugs. Drug types. Standard expressions and phrases. Herbal medicines. Natural source ingredients. Trends toward herbal medicines. Cloze-test. Mid-term test. In the pharmacy. OTC drugs and prescription drugs. Pharmacist-patient dialogue. Food and nutrition.The major components of food. Healthy diet. Terminology exercise. Deficiency diseases. Listening exercise on healthy nutrition. Discussion. Vitamins. Main sources of vitamins and minerals. Daily vitamin requirements. Pharmavit products. Infections. Antibacteril and antiviral drugs. Influenza. Pharmacist-patient dialogue Vaccination. Resistance to infections. Medical leaflets for educational purposes. Revision of previous topics. Test.

* * * * * * * * * * * * *

2nd semester PRACTICE (3 hrs/week) * Antibiotics. Types of antibiotics. Antibiotic resistance. Natural alternatives. Terminology exercises. * Analgesics. Types of analgesics, mechanism of action. Aspirin. Suffixes in medical language. * Inflammation. Anti-inflammatory drugs. NSAIDS. Corticosteroids. Vocabulary study. * Drugs in the treatment of skin disease. Ointments, lotions, creams. Antipruritics. Role play. * Allergy. Drugs in treatment of allergy. Regimens and diet. Environmental effects. Prefixes in the medical language. * The GI tract and drugs. Antidiarrhoeal drugs and laxatives. Emetics and antiemetics. Role play. * Revision of previous topics. Mid-term test. * Drugs for IBS and IBD. Diet and regimen. Discussion. * Ulcer. H.pylori. Anti-ulcer drugs. PPI. Diet and regimen. Terminology exercises. * Diabetes. IDDM, NIDDM. Oral anti-diabetics. The importance of good control. * Insulin treatment. Complications of diabetes. Compliance. Regimen and diet. Educational leaflets. * The pharmaceutical industry in Hungary. Hungarian drugs on the world market. Discussion. * The Faculty of Pharmacy at SZTE. The institutes and departments of the faculty. Scientific achievements. International cooperation. * General revision. Test. COMMUNICATION IN PHARMACY PRACTICE (ELECTIVE COURSE) * Introduction, course content. Importance of psychotherapy and communication in health care

*

Laws and ethical regulations concerning pharmacist’ communication Patient types and their handling

*

Practice: situations in pharmacy

*

Dispensing and consulting: verbal and non-

*

verbal elements of pharmacist-patient relationship I. *

Dispensing and consulting: verbal and nonverbal elements of pharmacist-patient relationship II.

*

Improving patient adherence with proper communication, special patients and situations in pharmacy I.

306 *

Improving patient adherence with proper communication, special patients and situations in pharmacy II.

*

Persuasion in pharmacy

*

Promotion of medicinal products


307 SYLLABUSES FOR 4TH YEAR PHARMACY STUDENTS

PHARMACEUTICAL ANALYSIS AND DRUG CONTROL

*

*

*

* *

* * * *

*

*

*

*

LECTURE Instrumental analytical methods are applied for characterization of starting materials and final products, and also for the control of pharmaceuticals and their decomposition products according to pharmacopoeias, together with the metabolites of pharmaceuticals. Electrometric methods: voltametry, polarography, amperometry, potentiometry, conductometry and oscillometry. Spectrophotometry, spectrophotometers, atomic and molecularspectra, UV and visible absorption spectrophotometry, chemical structure and qualitative and quantitative determination of pharmaceuticals by spectrophotometry. Spectrofluorometry and IR spectrophotometry. Structure determination and application of IR spectra for qualitative and quantitative purposes. Emission and atomicabsorption spectrophotometry and flame photometry. Nuclear magnetic resonance spectroscopy (NMR). Mass spectrometry (MS) and combinations of gas chromatography and high-pressure liquid chromatography with MS. Field ionization and chemical ionization mass spectrometry. Thermoanalytical methods (TG DTG. DTA, DSC). Optical rotation (ORD, CD), refraction and molecular refraction. X-ray diffraction (XRD), XRD analysis of solid pharmaceuticals and determination of particle size. Fundamentals of nuclear pharmacy. Radionuclide generators (liquid and solid column). Dosage forms of radiopharmaceuticals. Radioimmunoassay (RIA). Physical methods: density, solubility, viscosity, surface tension, melting range, eutectic temperature, dropping point, congealing point, boiling range, sublimation, flame coloration, residues of drying and ignition, loss on drying, acid- insoluble ash, etc. Chromatographic methods: adsorption column, partition column, paperchromatography, thin-layer chromatography (TLC), gas chromatography (GC), high-performance liquid chromatography (HPLC), ionexchange chromatography, molecular sieves, gel permeation (filtration), zone electrophoresis and counter-current distribution. Chemical purity and its control. The origin of impurities. Manufacturing product licensing standards. Pharmacopoeial standards. Identity, purity and assays of pharmaceuticals according to pharmacopoeias. Methods of drug registration, preclinical requirements, clinical trials (phases I-III), quality control during manufacturing (GMP) and quality control in postmarketing phase.

PRACTICE Pulvis neutracisus (FoNo) (a multicomponent divided powder)

Identity tests: frangula bark, sodium, carbonate, bismuth, magnesium. Assay: bismuth, magnesium.

Pilula somniferens (FoNo) Identity tests: hexobarbital, phenobarbital, lactose.

Assay: hexobarbital phenobarbital. Spiritus iodosalicylatus (FoNo) Identity tests: iodine, potassium, ethanol, iodide, salicylic acid. Assay: iodine and salicylic acid

Pulvis antidoloricus (FoNo)

Identity tests: ethylmorphine, caffeine, phenacetin, acetylsalicylic acid.

Assay: ethylmorphine, acetylsalicylic acid.

Unguentum hydrargyri amidochlorati (FoNo)

308 *

* * * * * * * * * * * * * * * * * * * * * * * * * *

* *

Quality control and separation of formulated Identity tests: mercury(II) and ammonia, chloride, pharmaceuticals. Separation of active ingredient/s sorboxethene. from the base and separation of active components into fractions. Separation of formulated pharmaceuticals according to Stass-Otto. Identification of separated components. General tests: sensory, heating test, solubility and acidity/alkalinity. Chemical examination: tests for elements (sulphur, halogen, nitrogen, etc.). Assay of halogens and sulphur according to Carius and Schoeniger. Analysis of pharmaceuticals on the basis of functional groups. Hydrocarbons (saturated, unsaturated and aromatic). Qualitative and quantitative determination of halogenated hydrocarbons. Compound with one or more hydroxy groups (alcohols and phenols). Ethers, aldehydes and ketones. Reactions of amines and alkaloids, their determination in galenicals and formulated dosage forms. Carboxylic acids and their derivatives. Their determination in galenical preparations and in vegetable drugs. Urea derivatives (ureides) and sulphonamides and their reactions. Amino acids and peptides, their synthesis and reactions. Quality control of peptide derivatives. Assay: marcury(II)amidochloride Suppositorium aminophenazoni (FoNo) Identity tests: aminophenazone Assay: aminophenazone Suppositorium antiemeticum (FoNo) Identity tests: lidocaine, atropine, caffeine. Assay: lidocaine, caffeine. Injectio algopyrini 50% Identity tests: noraminophenazone sodium mesilate Assay: noraminophanazonum natrium mesilicum Solution theobromoiodati (FoNo) Identity tests: theobromine, sodium, potassium, iodide, salicylic acid. Assay: theobromine, iodide. The constituents of the following dosage forms are identified by thin layer chromatography (TLC): Pulvis asthmalyticus fortis (FoNo) Pulvis asthmalyticus fortis cum atropino in tablettis (FoNo) Antineuralgica tablet Barbamid tablet Nasogutta ephedrini (FoNo) Identity tests: ephedrine Assay: ephedrine Chromatographic methods prescribed in the Pharmacopoeia VII. Sparsorium sulfaboricum (FoNo) Identity tests: sulphadimidine, boric acid. Assay: sulphadimidine. Measurement of physical data prescribed in pharmacopoeias (melting, boiling range, optical rotation, specific rotation, refraction, etc.) Identification of 20 pharmaceutical substances on the basis of pharmacopoeial tests. Methods of instrumental analysis.


*

*

* * *

309 Acidi- alkalimetry, direct titrations of strong acids and bases and weak acids and bases, back titrations, determination of organically combined nitrogen. Related with these all of the methods of pharmacopoeias and the prescriptions of the National Institute of Pharmacy (NIP) should be interpreted. Titrations in non-aqueous solvents: titration of alkali metal salts of organic acids and the titration of halogen acid salts of organic bases (alkaloids). Oxidation reduction titrations with potassium permanganate, iodine, potassium iodadate, potassium bromate, cerium(IV) sulphate solutions. Karl-Fischer titrations (aquametry). Argentometric titrations. Complexometric methods: direct and back titrations. Gravimetric methods in Ph. Hg. VII. Separation of complex mixtures of pharmaceuticals on the basis of chemical characters (weak acids, bases, amphoteric and neutral) of the components.

PHARMACEUTICAL TECHNOLOGY 7th semester

* * * * * * * *

LECTURES General instruction Coating process of solid dosage forms Requirements of coating process Sugarcoating, filmcoating, melted coating Instrumentation of coating process Capsules Categories of capsules Soft and hard gelatin capsules

* *

Capsule filling Tests for capsules

* * * *

Soaps, patches, preparations for veterinary use Application of soaps Process of preparation Medicated plasters

* *

FoNo VET and preparations Homeopathy

* * * * *

Preparation of mather tincture Preparation of potencies Dosage forms Drying Classification of methods

* * * *

Convective and radiation drying Driers Freeze drying Crystallization processes

*

Operations and methods

*

Crystallization from melt

PRACTICE Prescription pharmacy 2 General information Fire safety Solutions, repetition) Ph.Hg.VIII, FoNo VII.) Calculations decoctum, infusum

Collodium cum acido salicylico Fo No VII. dos. I (10,0 g) Gutta analeptica FoNo VI. dos. ½ (10,0 g). Otogutta chloramphenicoli FoNo Vet III. dos I (10,0 g) Suspensions Emulsions Units, Latin number

Solution against perspiration (Husz-Regdon) (50,0 g) Solutio gingivalis FoNo VII. dos. I (30,15 g) Nasogutta containing protargol Manuale Pharmaceuticum dos. ½ (16,8 g) Decoctum saponariae FoNo VII. dos. ½ (100,0 g) Self-made preparations Checking the dose

Infusum sennae cum magnesio sulfurico (100,0 g) Suspensio bismuthi subsalicylici pro infante FoNo VI. dos. I. (100,0 g) Suspensio expectorans FoNo VII. dos ½ (100,0 g) Emulsio olei jecoris FoNo VII. dos. ½ (100,0 g) Linimentum scabicidum FoNo VII. dos. ½ (50,0 g) Linimentum sulfadimidini FoNo Vet. II. dos. I. (50,0 g) Suspensio anaesthetica FoNo VII. dos. I (100,0 g) ½ cs Suspensio salicylamidi 2% cum sorbito FoNo VI. dos. I (100,0 g)

310 *

Spherical crystallization

* * * *

Packaging, packaging materials Requirements Safety Modification of biological activity

* *

Interactions in pharmaceutical technology Interaction and incompatibility

* * * * * * * *

Causes and types directions and guidelines Stability of drugs and dosage forms Stability ICH and structure of ICH Shelf life, reaction kinetics Automatization, instrumentation and monitoring of technological processes Product manufacturing process

*

On – line monitoring

* * * * * * *

Process development and optimization

* * * * * * * * * * * * * * *

* * * * * *

Suspensio zinci aquosa FoNo VII. dos. I (100,0 g) Zinkoxidshüttelmixtur NRF 2001 dos. I (100,0 g) Zinkoxyd-Schüttelpinselung NFA dos. I (100,0 g) Linimentum calcis FoNo VI. dos. ½ (50,0 g) Linimentum ammoniatum FoNo VII. dos. ½ (50,0 g) Incomp. III. (solution or suspension) (100,0 g) Gargarisma antisepticum Fo No VII. dos. ½ (50,0 g) Powders Divided and undivided powders Dusting powders Capsula operculata Incompatibility Tea mixtures Emulsions, suspensions Powder dividing by eyes, checking with measurement Powder dividing by Hunfalvyl, checking with measurement Capsula operculata calibration Pills Calculation, writing of prescription

Infusum sennae cum magnesio sulfurico (100,0 g) Pulvis coffeini 50 mg FoNo VII. dos. 1/3 (No. X) Pilula coffeini 50 mg FoNo VII. dos. I (No. XXX) Sparsorium antisudoricum FoNo VII. dos. ½ (34,2 g) Pulvis calcii lactophosphorici FoNo VII. dos ½ (25,0 g) Suppository Preparing of suppository with moulding and handmade method Calibration of moulding forms

Suppository containing Bismuthum subgallicum (No. X) Hard gelatine capsules containing Ascorbic acid (No. XX) Pulvis bismuthi tannici FoNo VII. dos. ½ (No. X) Suppositorium analgeticum forte FoNo VII. dos. ½ (No. III) Suppositorium antipyreticum pro infante FoNo. VII. dos. I (No. VI) Suppositorium paracetamoli 60 mg FoNo VII. dos. I (No. X) Vaginal dosage forms Stifts Powders Calculation for moulding and hand-made method

Sal ad rehydrationem cum natrio hydrogencarbonico pro parvulo FoNo VII. dos. I. (30,8 g) Oralytpulver 60 SR 2001 dos. I (28,0 g) Oral Rehydration Salts BP 1998 dos. I (27,9 g) Emulsio paraffini cum phenolphthaleino FoNo VII. dos. ½ (100,0 g) Globulus containing Zincum sulfuricum (No. IV) Suppositorium laxans FoNo. VII. dos. I (No. X) Pilula tonisans FoNo VI. dos. ½ (No. XXV)

Curriculum 2014/2015 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

311

Ovulum metronidazoli FoNo VII. dos. I (No. X) Suppositorium ad nodum FoNo. VII. dos. I (No. X) Suppository containing Benzocainum Manuale Pharmaceuticum dos. 1/10 (No. X) Inkomp. VI. dusting powder (50,0 g) Eoszacharum containing barbitalum (No. X) Suppository

Calculation of prescription components Globulus metronidazoli compositus FoNo VII. dos. I. (No. X) ½ g.globulus Suppositorium expectorans FoNo VI. dos. I. (No. VI) Suppository for children Manuale Pharmaceuticum dos. I (No. X) Effervescent powder for x-ray (Manuale Pharmaceuticum dos. I (16,6 g) SELF-MADE PREPARATIONS Preparation of sterile and aseptic dosage forms Aseptic preparation Eye-drops Solutions for eye-drops

Solutio ophthalmica cum benzalkonio Solvens pro oculoguttis cum benzalkonio cum thiomersalo Solvens viscosa pro oculoguttis cum thiomersalo cum cetrimido Hydrogelum carbomerae pro oculoguttis FoNo preparations

Oculogutta antidota Oculogutta atropini Oculogutta carbomerae Oculogutta chloramphenicoli Oculogutta erythromycini Oculogutta gentamicini Oculogutta homatropini Oculogutta indosoli Oculogutta naphazolini Oculogutta neomycini Oculogutta neonatorum Oculogutta pilocarpini Oculogutta polymyxini Oculogutta rifampicini Oculogutta scopolamini Oculgutta tetracaini Oculogutta viscosa Oculogutta zinci Eye ointments Bases of eye ointments

Oculentum simplex Oculentum hydrosum Oculentum basis FoNo preparations

Oculentum Oculentum Oculentum Oculentum

dionini erythromycini neomycini neomycini cum prednisolono

312 * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

Aerosols, inhalasols Concentration of infusion solutions, isotonic calculations Sterilization Pyrogens, pyrogen removal methods Filtration Large volume parenteral preparations Infusions with electrolyte

Infusio natrii chlorati Infusio salina Infusions with sugars

Infusio glucosi Infusio manniti Infusio sorbiti Infusions with electrolyte and sugars

Infusio glucosi cum kalio Infusio glucosi salina Investigation of large volume parenteral preparations Supplementary infusions Stock solution

Natrium lacticum solutum 20% pro infusione Infusions for correction of acidosis

Infusio natrii lactici Infusio natrii hydrogencarbonici Infusions for correction of alkalosis

Infusio gastrica Dialysis Peritoneal dialysis solutions

Solutio pro dialysi peritoniale I. Solutio pro dialysi peritoniale II. Perfusion solutions Plasma substitute infusions

Infusio dextrani Parenteral nutrition Preparation of parenteral nutrition infusion

Magistral parenteral nutrition infusion Injections

Injectio natrii chlorati Injectio glucosi Injectio papaverinii chlorati Injectio coffeini natrii benzoici Investigation of injections Non-heat sterilizable injections

Injectio urea Injectio aethylmorphinii chlorati Multidosage injections

Injectio procainii chlorati Injectio atropinii sulfurici Powder ampoules

Kalium chloratum sterilizatum Injectio trometamoli cryosiccata Liofilization Emulsion and suspension type injections Visit in the Central Pharmacy


313

8th semester

* *

LECTURE Pharmaceutical technology and biopharmaceutics LADMER Biopharmaceutical considerations in drug product design Bioavailability Biopharmaceutical Classification System Effect of the physico-chemical properties of the drugs and the type of dosage forms on the biological response Physico-chemical profiling of the drug Solubility, lipophylicity, ionization (pKa), log P

* * * * * * * * * * *

Permeability Absorption in the GI tract Absorption in the mouth Absorption in the gastric tract Absorption in the intestinal tract Colon therapy Rectal therapy Traditional and modified drug release preparations Parenteral application and pharmaceutical parameters Pharmacokinetics models Clearance

* *

Factors effecting drug absorption by injection Inhalasols

* * * * * * *

Lung and its biopharmaceutical aspects Dosage forms and their special requiremets Lung delivery systems Dermal and transdermal drug delivery systems Skin parameters Permeation enhancers Ointment bases and application

* * * * *

Patches and their mechanism Biopharmaceutical aspects of dental, vaginal ophthalmic

* *

otic and nasal preparations

* *

Rectal drug delivery systems Rectal dosage forms

* *

Formulation factors Drug absoption modifiers

* * * *

Pediatric dosing and dosage forms Pediatric pharmacokinetics and pharmacodynamics Excipients Administration routes

* * * * * *

PRACTICE Prescription pharmacy 3 General rules Repetition of liquid dosage forms

Suspensio bismogeli (FoNo VII., 100 g) Sirupus kalii chlorati (FoNo VII., 100 g) Repetation of solid dosage forms

Sparsorium antimycoticum (FoNo VII., 50 g Suppositorium noraminophenazoni 500 mg (FoNo VII., N° VI.) Ointments, Creams, Pastes, Hydrogels

Globulus glycerini boraxati (FoNo VII., N° X.) Ung. salicylatum 1% (FoNo VII., 30,0 g) Ung. boraxatum (FoNo VII., 50,0 g) Hydrogelum antisudoricum (FoNo VII., 25,0 g Ung. nystatini (FoNo VII., 50,0 g Ung. carbamidi (FoNo VII., 25,0 g Ung. dithranoli 0,1% Incompatibilities

Inkomp. IV. – ointment 30,0 g) Ung. camphoratum ad pernionem (FoNo VII., 30,0 g) Ung. lidocaini ad rhagades (FoNo VII., 20,0 g) Pasta antirheumatica (FoNo VII., 175,0 g [1/2 dózis]) Ung. antisepticum (FoNo VII., 30,0 g) Ung. contra panaritium (FoNo Vet. III., 50,0 g) Ung. nasale (FoNo VII., 10,0 g) Detergens sulfuratum (FoNo VII., 100,0 g) Zincum gelatinosum 50,0 g (FoNo VI. elıirata) Lanstein paszta Manuale Pharmaceuticum 100,0 g Hydrophile Metronidazol-Creme 2% Standardisierte Rezepturen 2001 (NRF/SR) 100,0 g Anionische Nystatin-Creme 100,0 g Homeopathy Aromatherapy SELF-MADE PREPARATIONS Industrial preparation and investigation of solid dosage forms Cycle 1 Powder rheological investigation and qualification of raw materials with ASTM apparatus (effective and auxiliary materials). Powder rheological investigation and qualification of raw materials with PTG-1 equipment (effective and auxiliary materials). Particle size investigation of raw materials with a vibration sieve analysis method. Moisture content investigation of raw materials. Compactibility investigation of materials. Investigation of water absorbing capacity of raw materials and powder mixtures.

314 *

Therapeutic systems I

* *

Solid systems Biodegradabile polymers

*

Therapeutic systems II

* *

Semisolid systems TTS

* *

Lyotropic liquid crystals Micro- and multiple emulsions

* *

Microsferes, liposomes In vitro dissolution test methods

*

Ex vivo and in vivo methods

*

Characterisation of dissolution profiles

*

Comparision of dissolution profiles IVIVC

*

Biopharmaceutical aspects of original and generic preparations

* * * * * * * * * * * * * * * * * * * * * * * * * *

Preparing granules with high shear mixer (solvent granulation with Pro-c-epT equipment). Preparing granules (binder granulation with LuxRoyal equipment). Preparing granules with centrifugal granulator (binder granulation with Freund CF-360 equipment). Preparing granules with fluid granulator (binder granulation with Strea-1 equipment). Capsule filling and blistering. Mass control of filled capsules. Cycle 2 Compressibility investigation of different materials with the use of different compression forces. Recording and analysing differen pressure curves. Geometrical investigation of tablets prepared by different compression forces. Physical investigation of different tablets (breaking hardness, friability, etc.). Tablet preparation by direct compressing without auxiliary materials with the use of eccentric tablet machine. Tablet preparation by direct compression with auxiliary materials with the use of eccentric tablet machine. Tablet preparation with rotary tablet machine. Preparing and mechanical investigation of tablets with effective materials compressed with different compression forces. Water absorbing capacity of different tablets. Dissolution and solution test of different tablets. Sartorius resorption test. Cycle 3 Investigation of film forming temperature with different film forming polymer compositions. Film coating of granules in centrifugal granulator. Film coating of granules in fluid granulator with the use of Wurster-column. Film coating of tablets. Sugar coating of tablets in drageé pan. Dissolution test of enteric coated tablets. Investigation of diffusion. Designing, preparing and investigating of new tablet composition. Investigation of dosage forms Investigation of suspensions:  distributional stability investigations of flocculated and non-flocculated suspensions  deteremination of the type of sedimentation and the half life time  investigation of the effect of different additives on the sedimentation process. Investigation of air humidity on the geometrical parameters of tablets:


* *

* *

* * * * * *

* * * * * *

* * * *

PHARMACODYNAMICS-TOXICOLOGY 7th semester LECTURE * Drugs acting on ganglionic transmission. Adrenergic neuron blockers. Directly acting parasympathomimetics. Indirectly acting parasympathomimetics. Parasympatholytics. Atropine poisoning. Antispasmodics (papaverine and related drugs) * Pharmacology of sympathomimetics

*

Pharmacology of sympatholytics

315  determination the influence of 100% relative air humidity on the weight and geometrical parameters of phenylbutazone tablets. Investigation of polymer films:  determination of solving time of gelatin films with different thickness in artificial gastric and intestinal juice. Investigation of hydrophyl sols’viscosity changing:  study the viscosity changing by electrolites of the Mucilago methylcellulosi and Mucilago hydroxyaethylcellulosi. Investigation of ointments I:  Characterization of water-free ointment bases with the help of physical investigations. Investigation of ointments II:  Determination of washability and rheological features of ointments. Investigation of ointments III:  Consistency characterisation of the ointments by determinating viscosity, spreadability and adhesion. Determination of average molecular weight of dextrane:  Determination of average molecular weight of dextrane with measuring density and viscosity. Water-absorption of polymers:  Investigation of the water-absorption process by means of Enslin-apparatus. Light permeability determination of glass containers:  Investigation of transmittancy of glass containers with different colours in a given wave lenght range. Investigation of drug release by means of the agar diffusion plate method:  Investigation of drug release from different ointments. Determination of drop weight:  Investigation of the effect of different additives on the drop-weight and surface tension.

PRACTICE Administration of drugs to experimental animals. Demonstration of the local and systemic effect. Enternal and parenteral route of administration.

Dose-response relationship of drugs. Indication of microsomal enzymes by phenobarbital. Statistical evaluation of experimental data. Drug interactions, competitive antagonism. Experiments in isolated guinea pig ileum. Dose-response relations. General anaesthesia. Demonstration of anaesthesia induced by ethylether. Intravenous anaesthetics. Narcotic analgesics. Methods for demonstration of analgesic activity. Evaluation of analgesic potency. Neuroleptics and tranquillizing drugs. Evaluation of behavioral effects of drugs in mice and rats

316

*

Diuretics and antidiuretics

*

Antianginal agents. Antihyperlipidemic agents

*

Cardiotonics, treatment of congestive heart failure

*

Antiarrhythmic agents

*

Antihypertensive therapy. Calcium channel blockers. Drugs acting on renin-angiotensin system

*

Pharmacology of blood coagulation. Thrombolytics. Drugs acting on platelets.

*

Steroidal antiinflammatory drugs. Non-steroidal antiinflammatory drugs. Antihistamines

*

*

*

Pharmacology of insulin and its congeners. Orally acting antidiabetics Antitussive agents and mucoregulators. Antiasthmatic agents. Drugs used in the treatment of peptic ulcer.

*

Digestive agents, digestive enzymes

*

Laxatives & prokinetic agents

*

Drugs for inflammatory bowel disorders, obstipants

*

Drugs acting on bile. Hepatoprotectives

*

Antiemetics

*

(locomotor activity, jumping test, motor coordination). Convulsants and analeptic drugs. Effects of strychnine and pentylenetetrazol. Anticonvulsant drugs. Reversal of respiratory depression. Investigation of local anaesthetics on frog skin and rabbit cornea. In vitro demonstration of nerve block anaesthesia. Agents acting on the autonomic nervous system. Effects on isolated frog heart, the pupil of rabbit and the salivary secretion of rat. Agents acting on the autonomic nervous system. Demonstration of drug effects on isolated ganglia and nictitating membrane of cat. Agents acting on the automic nervous system. Effects on cholinergic and adrenergic drugs on the blood pressure of anaesthetized animals. Agents affecting the smooth muscle function. Demonstration of the action of drugs on isolated ileum. Drugs affecting the striated muscles. Muscle relaxant effect of tubocurarine and succinylcholine. Effect of cardiotonics on isolated frog heart. Demonstration of cardiac action with the help of ECG. Vasoconstrictor and vasodilator effect of drugs. Laewen-Trendelenburg experiments. Diuretic effect of drugs in rats and in anaethetized rabbit. Drugs acting on blood coagulation. Evaluation of prothrombin activity. Anticoagulant activity of heparin and acenocoumarol. Choleretic and laxative drugs. Biliary excretion of BSP. Investigation of laxative effect. Pharmacological effects of histamine and antihistamines. Effect of drugs on permeability of capillaries in rat. Investigation of antiphlogistics. Demonstration of drug effect in rat-paw edema, exudative pleuritis and cotton-granuloma tests. Toxicological invesitgations. Benefit of activated charcoal. Demonstration of leucopenia produced by cytotoxic agent. Determination of cholinesterase activity after intoxication with organophosphate substances.

8th semester * * * * * * * * *

Hypnotics and sedatives. Pharmacology of barbiturates, benzodiazepines, zolpidem, zopiclone, zaleplone, and miscellaneous drugs. Intoxication with sedato-hypnotics. Ethanol, alcoholism, alcohol withdrawal Pharmacology of anxiolytic drugs Definition of general anaesthesia, stages. Inhalational general anaesthetics. Intravenous general anaesthetics. Premedication and complementary medication of general anaesthesia. Neurolept-analgesia Mechanism of action of local anaesthetics. Therapeutic use of local anaesthetics Opioid analgetics. Pharmacology and therapeutic use of morphine. Acute morphine intoxication and abuse. Semi-synthetic and synthetic opiates. Opiate antagonists. Pharmacotherapy of epilepsies

Curriculum 2014/2015 * * * * * * * * * * * * * * * * * *

317

Therapy of Parkinson’s disease, secondary parkinsonism Therapy of Alzheimer’s disease and sclerosis multiplex Neuroleptics Therapy of endogenous depression Psychostimulants. Pharmacology of amphetamine Hallucinogens Peripheral skeletal muscle relaxants Centrally acting skeletal muscle relaxants Pharmacology of bone metabolism. Osteoporosis, rheumatoid arthritis, osteoarthritis Pharmacology of female sex hormone and their antagonists Pharmacology of androgens and their antagonists General characterisation of contraceptives, oral contraceptives Therapy of infertility Pharmacology of pituitary hormones Pharmacology of thyroid gland Drugs acting on the uterine function Pharmacology of obesity Therapy of erectile dysfunction

PUBLIC HEALTH AND Preventive Medicine 7th semester LECTURE (2 hrs/week) *Introduction. The aim and scope of public health and preventive medicine. Basic knowledge of demography. *Basic knowledge of epidemiology, main types of epidemiological studies. Health status of world population. *Epidemiology of cardiovascular and cerebrovascular diseases, and malignant tumours. *Epidemiology of metabolic, gastrointestinal, and chronic respiratory diseases. Epidemiology of accidents and suicide. *General epidemiology of infectious diseases. Prevention, vaccinations. Epidemiological safety. Epidemiology of infectious diseases: airborne diseases. *Epidemiology of infectious diseases: enteric, hematogenic and lymphogenic diseases, cutaneous and sexually transmitted diseases. *Epidemiology of infectious diseases: zoonoses, transmissible spongiform encephalopathies, health care associated infections, infection control (nosocomial surveillance). *HOLIDAY *Epidemiology of smoking, alcohol and drug consumption (health risks, prevention). *Nutrition in public health. Healthy diet. Malnutrition. Food quality and safety. *Structure and operation of health systems. Health and health care in the family (mother, infants, youth, elderly). *Environmental health. Climate change and health. Health effects of physical, chemical and biological factors of micro- and macro environment. *Occupational health. Occupational diseases caused by physical, ergonomic and psychosocial exposures. *Health effects of occupational and environmental chemical exposures. Risk assessment and communication. Chemical safety.

ETHICS IN PHARMACY Lectures * Ethics and morality. History of ethics, Ethical theories. Fields of ethics * Code of Practices, their role in regulation, functions, general content. * Ethics in health care (autonomy, non-maleficence, beneficence, justice) * Ethics of the therapeutic relationship * Allocation of resources in health care, relationship between economy and ethics. Organ donation and transplantation * The beginning and end of life: abortion, assisted reproductive technics, euthanazia, hospice * Research ethics * Sale and promotion of medicinal products, ethical aspects and regulations * Ethics in pharmacy, Code of Pharmacy Practice Seminars * Ethics of pharmacy practice. Pharmaceutical care in pharmacy; Private life of a pharmacist

318 *

Pharmacist and different relationships: patient, phsysician, assistant, pharmacist, other health care workers

*

Competency fields of a pharmacist, Promotion and marketing in pharmacy, keeping the secret of the patient * Pharmaceutical service (strike, misuse of drugs) * other topics, exam consultation DRUG REGULATORY AFFAIRS 8th semester * Introduction *

Bacis Acts and Regulations within Pharmacy

*

Regulation of drug research and human clinical trials

*

Drug manufacture, procurement, wholesale distribution

*

Retail medicine supply (to patients) – regulation concerning community pharmacies

*

Regulation of hospital pharmacies

*

Marketing authorization process of medicinal products

*

Prescribing and dispensing of medicinal products

*

Regulation of herbal medicines (mostly in Europe)

*

Regulation of controlled substances (narcotic and addictive products)

*

Advertising and promotion of medicinal products

*

Drug pricing, drug reimbursement or subsidy, governmental drug budget control

*

Regulation of hazardous waste handling

*

Pharmacovigilance-system

INTRODUCTION TO ECONOMICS 7th semester * Introduction lecture: affiliation between economics and pharmaceutics, introduction of the necessity of the subject, statement of the syllabus * Theoretical economics: efficacy, change and comparative benefits, act of decreasing border profit, formation of money and its functions * Theoretical economics: market processes (demand, offer, rate, benefit, economic profit, inventory profit), market persons * Theoretical economics: competition, monopoly, price searching (price flexibility, price discrimination) * Theoretical economics: income allocation, externalies, markets and state, total performance of economic systems * Theoretical economics: national economic policy, international change, employment and unemployment * Accountancy and analysis: basic definitions (property, subject tools, etc.), movement of tools and sources, economic events, certificates * Accountancy and analysis: accounting of economic events, definition of expenses and result, indexes of financial state of employments * Basics of marketing: marketing research, marketing channels, price policy, marketing communication * Basics of marketing: marketing planning, marketing strategy, marketing service * Business planning, financial planning: theory of development of business and financial plan * Fiscal and monetary policy: functions of the state, subsystems of the finances, persons of financial system and their functions * Basics of pharmacoeconomics: economic characterizations of the health care market, health care systems, comparability of medicine doses (ATC, DDD), comparative standard indexes of therapies’ efficiency (NNT, NNH, etc.) * Basics of pharmacoeconomics: mesurement of quality of life (QALY, questionnaires), pharmacoeconomic analyses

Curriculum 2014/2015 INTRODUCTION TO LAW (SOCIAL LAW) 7th semester * Basic terms, introduction to the law *

Basics of constitution and state organizations

*

Constitutional law

*

Basics on the European Union, European Law

*

Basics of civil law: contracts

*

Basics of civil law: partnerships and self-employment

*

Intellectual property

*

Basics of criminal law

*

Basics of labour law

*

Basics of tax law

*

Basics of social security

*

Equal treatment

HUNGARIAN FOR PHARMACEUTICAL PURPOSES 1st semester

* * * * * * * * * * * * * *

PRACTICE (2 hrs/week) Video program “The Role of the Pharmacist in the Community”. Discussion, new words, expressions. A modern pharmacy. General rules, requirements. The laboratory. Reading comprehension, vocabulary practice. Briefing pharmaceutical news. Translation of drug descriptions. Basic vocabulary. The specific jargon of the text. Summary. Health education in Hungary. General vocabulary. Analysis and discussion. Translation: Bactroban. Vocabulary study. Cloze-test. Revision. Mid-term test. Iron deficiency. Word building exercise. Briefing. AIDS. Reading comprehension, discussion. Terminology exercise. Translation: Lipanthyl. Vocabulary study. Cloze-test. Analyzing patient information leaflets: Aurobin. Discussion. Life expectancy in different countries. Discussion. Role play. Translation: Librium. Vocabulary study. Terminology exercise. Revision. Test.

2nd semester

* * * * * * *

PRACTICE (2 hrs/week) Pharmacotherapy. Reading comprehension. Vocabulary study. Geravit Pharmaton. Reading comprehension. Vocabulary practice. Tranquillizers: Seduxen. Vocabulary study. Standard expressions. Translation. Use and misuse of drugs. Addiction. Standard expressions and phrases. Immunopathology. Reading comprehension. Vocabulary study. Cloze-test. Interferon. Translation. Vocabulary study. Short news from “Magyar gyógyszerészet”. Revision. Mid-term test.

319

320 * * * * * * *

Taleum nasal spray. Vocabulary study. Role play. Erythromicin. Standard expressions. Word building exercises. Translation: Tarivid. Use of vocabulary. Cloze-test. Committee on the Safety of Medicines. Drug tests on animals. Discussion. Outstanding personalities of the Faculty of Pharmacy, their scientific achievements. General revision. Preparation for the final exam. Final test, exam.

CLINICAL LABORATORY DIAGNOSTICS 8th semester Lecture: *

-Obtaining biological samples, general pretest preparation

*

-Diagnostics of anorganic ions

*

-Diagnostics of carbohydrate metabolism

*

-Diagnostics of lipid metabolism

*

-Proteins

*

-Rest nitrogen, creatinine, ammonia, urea and bilirubin determinations

*

-Enzymes, enzyme diagnostics

*

-Immunoanalytical methods

*

-Diagnostics of hereditary metabolic diseases

*

-Endocrinological tests

*

-DNA based diagnostical tests (PCR, real-time PCR, DNA array)

*

-Quality control

Practice: *

-Urine analysis

*

Hematology (sampling, test tubes, complete blood count, clotting probes)

*

Tumormarkers

*

Pregnancy tests

*

POCT for blood glucose and hemoglobin A1c

*

POCT for cholesterol and triglycerades

PHARMACY ADMINISTRATION 8th semester PRACTICE (2 hrs/week) The aim of the course is to teach pharmacy students about the essential administrative and management steps during everyday work in a community pharmacy. The course gives insight to national and international practices. Topics covered during the course: type of pharmacies ownership pharmacies

Curriculum 2014/2015 activities of community pharmacies storing medications counterfeit medication Price of medicines Health insurance systems, medication reimbursement Prescription (forms, requirements, essential elements) Prescribing errors, medication errors

321

322 SYLLABUSES FOR 5TH YEAR PHARMACY STUDENTS

PHARMACODYNAMICS III. 9th semester * Antineoplastic drugs: alkylating agents, antimetabolites * Immunsuppressants and immunstimulants * Basic principles of the chemotherapy: resistance, selective toxicity * Penicillins, cephalosporines * Pharmacology of the sulfonamides * Aminoglycosides * Tetracyclines, macrolides * Fluoroquinolones and chloramphenicol * Drugs used in the treatment of tuberculosis * Antiviral drugs * Drugs used in the treatment of malaria * Antifungal agents * Antiseptic agents * Antiparasitic agents * Pharmacology of the vitamins * Pain managament * Drug treatment in perinatology and gerontology * Headache disorders: migrain and cluster * Principles of toxicology and treatment of poisoning

FUNDAMENTALS OF CLINICAL THERAPY * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

Internal medicine The patient's examination The more important diseases of the circulatory system and their therapy Diseases of the respiratory system therapy Diseases of the kidneys therapy Diseases of the digestive system therapy The most important diseases of the ductless glands and their therapy Diseases of the blood therapeutic possibilities Surgery Resuscitation restitution of the circulation and of the breathing Mass accidents emergency service Skull-injuries commotio, contusio, compressio: fracture of bones sprain Dull-damages of the chest The types of bleeding and their therapy Burning damages Appendicitis, ileus, acute abdomen Pediatrics The periods of childhood The main stations of the baby's and child's normal development The conditions of the reasonable treatment The various types of treatment, the sorts of taking in the drugs which are the rules in childhood? Special standpoints of drug use in Pediatrics Methods of antifebrile therapy in Pediatrics Antispasmodic drugs in Pediatrics The treatment of circulatory insufficiency and shock What to do in case of status asthmaticus? The most common complaints of the respiratory system in childhood treatment. Obstetrics and Gynaecology Pharmacological influence of the uterus' activity /oxytocin, prostaglandins, beta-mimetics etc./

Curriculum 2014/2015 * * * * * * * * * * * * * * *

323

The starting of a delivery Disseminated intravascular coagulation /DIC/ placenta praevia, missed abortion, rupture of the uterus "Extrauterin" pregnancy Acute inflammatory diseases in obstetrics /"post partum" endomymetritis, septic abortion etc./ Torsion of ovarian cyst's peduncle Neurology, psychiatry The role of psychiatry in the education of medical and pharmacy students. The symptoms of increased intracranial pressure and its treatment The course of parkinsonism and its treatment Schizophrenia Psychosis maniaco-depressiva Neurological, psychiatric and social consequences of alcoholism Polytoxicomania Suicide Enumeration of psychic abnormalities and the principles of the treatment

CLINICAL PHARMACY I. * * * * * *

* * * * * * * * * *

Introduction to Clinical Pharmacy Activity round and function areas of clinical pharmacy. General and special works of clinical pharmacy. Connection of clinical pharmacist with pharmacotherapy and drug order. Drug safety. The role and works of pharmacist in the in-patient provision Place of pharmacist in medical attendance. The role of pharmacist in drug provision. Connection with patients, physicians, nurses, members of other disciplines. Clinical importance of drug formulation Applied drug technology as a paret of clinical pharmacy. Formulation of oral preparations. Liquid oral drug formulations. Formulation of parenteral drugs, formulation of intramuscular, intravenous injections. Parenteral therapeutic systems. Rectal drug formulations, local drug formulations. Non-compliance Idea, definition, extent and importance of non-compliance. Methods for assessment of non-compliance. Major reasons for non-compliance. Strategies for improving compliance. Therapeutic drug monitoring Possibilities in public pharmacy practice. Hospital practice (Drug history taking. Monitoring of drug effectiveness. Drug blood-level monitoring. Measurement methods). Drug side-effects Drug side-effects. Classification, reasons of drug side-effects. Drug side-effect monitoring systems. Drug interactions Influental factors of development of drug interactions. Mechanism of drug interactions, its evaluating methods. Clinical important interactions. Drug information Topics connected with drug information. The role of pharmacist. The sources of information, its storage and retrieval.

VETERINARY PHARMACY (COMPULSORY ELECTIVE SUBJECT) 9th semester - Introduction to veterinary pharmacy. - Legal requirements for the sale and supply of veterinary medical products. - Business and financial aspect of veterinary products. - Comparative anatomy and physiology. - FoNo Vet III. Veterinary vaccines - Animals and human health.

324 - Food-borne zoonoses. - Complementary and alternative therapies. - Health and nutrition of horses and pigs. - Diseases of cattle, sheep and goats - Diseases of cats and dogs - Pigeon healthcare. - The diseases and healthcare of bees and fish. - The diseases and healthcare of other small pets (Reptiles, aviary and cage birds, small mammals). - Veterinary vaccines - The management of animal soft tissue injuries - Laboratory animals, knock-out animals, transgenic animals - Genetically modified foods and organisms

PHYTOTHERAPY - AN INTRODUCTION TO HERBAL MEDICINE (COMPULSORY ELECTIVE SUBJECT) 9th semester

*

* * * *

*

*

*

LECTURE (2 hrs/week) History and modern phytotherapy traditional medicinal systems that use plants (TCM, ayurveda, North-America, Africa, European traditions etc.); the principles of evidence-based phytotherapy Herbal product regulation International outlook Phytochemical overview of herbal active substances Alkaloids, glycosides, flavonoids, saponins, tannins, bitters, mucilages etc. The issue of safety and efficacy Standardization, quantification, preclinical and clinical trials, the value of tradizional use Plants and the nervous system Anxiety, insomnia Depression Plants and the digestive system Stomatitis, gingivitis Dyspepsia Flatulence Gastritis, eptic ulcer Kinetosis Obstipation Diarrhea Plants an the cardiovascular system Congestive heart failure Atherosclerosis, hypertension Chronic venous insufficiency, haemorrhoids Arterial occlusive disease Plants and the renal system Infections of the urinary tract


*

*

*

*

*

Diuretics, urinary stones Plants and the respiratory system Cold and flu, rhinitis Expectorants Mucilaginous drugs, antitussives Immunomodulatory drugs Plants and the reproductive system Premenstrual syndrome Menopausal symptoms Benign prostatic hyperplasia Plants and metabolic diseases Lipid metabolism Glucose metabolism Obesíty Plants and the cutaneous system Antiseptic herbal drugs Anti-inflammatory drugs Wound healing and post-traumatic drugs Plants in the treatment of pain Headache Migraine Articular and muscular pain Adaptogenic plants

PHARMACEUTICAL PSYCHOLOGY (COMPULSORY ELECTIVE SUBJECT) 9th semester LECTURE (2 hrs/week) 1. Introduction 2. Compliance, adherence, basis of communication 3. Communication barriers I. 4. Communication barriers II. 5. Impression formation 6. Giving information, patient education 7. Non-verbal communication I. 8. Non-verbal communication II. 9. Enhancing the pharmacist-patient relationship 10. Test 11. Consultation

PHARMACEUTICAL CARE 9th semester LECTURE (2 hrs/week) Methods of patient counselling Sunburn Allergic rhinitis, atopic dermatitis Asthma, COPD Diabetes mellitus Thromboembolism Musculoskeletal disorders Common cold, Flu Antibacterial therapy Hypertension Headache

325

326 Insect bite Constipation & diarrhoea EVERYDAY DERMATOLOGY (COMPULSORY ELECTIVE SUBJECT) 9th semester LECTURE (2 hrs/week) Cutaeous structure; layers & typical cells Basic physiological functions of the skin Acne Seborrhoic dermatitis (face and scalp) Diseases of the Hair (alopecia areata, telogen effluvium, male pattern alopecia) Psoriasis Dermatophyte infection of the skin Candidiasis Impetigo contagiosa Folliculitis Erysipelas Herpes labialis, herpes genitalis Herpes zoster Kaposi’s sarcoma Gonorrhoea Syphylis Scabies Urticaria Allergic contact dermatitis Topical corticosteroids: recommandations for use Common warts Condyloma acuminatum AIDS Pityriasis versicolor Dermatological vehicles QUALITY ASSURANCE (COMPULSORY ELECTIVE SUBJECT) 9th semester * Introduction: pharmaceutical quality assurance Definitions of „quality” Quality control and conformity assessment From quality control to quality assurance. PDCA Levels of the quality assurance/manegement * Certain defect analysis and quality monitoring methods * Quality assurance in the standardised and regulated fields: different sides of the national quality assurance systems * The ISO quality assurance standard series * Good Manufacturing Practices * Good Laboratory Practices * Good Clinical Practices * Good Pharmacy Practices and quality assurance in pharmacies


327 Vow to be made by 1st year medical and dental students

I, ……… name …….., / as the student of the University of Szeged / promise solemnly / that I will observe and adhere / to the rules and regulations / of the Hungarian Republic. / Also I will observe and adhere / to the rules and regulations / of the University of Szeged / and I am aware of these. / I devote all my best efforts / to go through with my studies here / as efficiently as possible. / I will give my teachers / the respect and gratitude / which is their due. / I will respect the secrets / which are confided in me / even after the patient has died. / I will maintain by all means in my power / the honor and the noble traditions / of the medical and dental profession./ I will devote my time and efforts / to learn the progressive achievements / of the basic and clinical sciences / in order to use this knowledge / for advancing medicine and dentistry, / for the care of my patients / and to promote man's progress on Earth. / I make these promises solemnly, / freely, / and upon my honor.

Oath to be taken by medical and dental graduates I, ……… name …….., / on this occasion / of my admission / to the ranks of the medical profession / swear on my honor / to devote my talents and knowledge / to the benefit of mankind. I shall hold / University of Szeged in esteem. I shall count those / who have instructed me / in the science of medicine / as my masters, / and shall show them / gratitude and respect at all times. I shall impart my medical knowledge / and experience / to the generations of physicians to come. / I shall constantly labour / to increase my erudition / with a view to developing / and advancing medical science. / I shall practice my profession / conscientiously. I vow to devote / my medical knowledge / to the protection of health / and to the benefit of the sick. / I shall treat / and advise patients / in the best of their interest / and to the best of my knowledge / and convictions / and I shall strive / to safeguard their health / against hazardous / and injurious effects. I shall reveal no secret / concerning my fellow men / whether learned within my practice of medicine / or outside it / unless the law demands this. I shall inform the patients / and also their relatives / if the patients’ interest so requires / as to the patients’ condition / and the method of treatment / in a timely and considerate manner. / I shall issue a medical certificate / only in accordance with my true convictions. I shall conduct myself / towards the patients / my fellow physicians and the society as a whole, / in a matter befitting my calling as a physician. / I shall preserve the honor / of the medical profession / and its noble traditions. I shall not be hampered / from fulfilling the duties of my profession / on the grounds of social, / political, / national, / racial / or religious distinction. I take this oath solemnly / and of my own free will.

Vow to be made by 1st year pharmacy students I .................name................./ as the student of the University of Szeged / promise solemnly / that I will respect the Constitution and laws/ of the Hungarian Republic. I will also observe and adhere / to the rules and regulations / of the University of Szeged. / I promise to devote all my best efforts / to go through with my studies here / as efficiently as possible. I will give my teachers / the respect and gratitude / which is their due. / I will respect the secrets of the patients / which are confided in me / during my course of studies. / I will maintain by all means in my power / the honor and the noble traditions / of my profession. I will devote my time and efforts / to learn the progressive achievements / of the basic and clinical sciences / in order to use this knowledge / for advancing medicine, / for the care of my patients / and to promote man's progress on Earth. / I make these promises solemnly, / freely, / and upon my honor.

Oath to be taken by pharmacy graduates I....... name....., / hereby swear / that I shall always maintain / an attitude in accordance / with my vocation as a pharmacist. / In my professional practice, / I shall proceed with the greatest degree / of conscientiousness / and with the utmost diligence. / I shall always behave / worthy of my profession. / As part of the healing work, / I shall devote all my energies / to the protection and recovery / of the health of the individual and society. / I shall not reveal any data / concerning the health status / or the medication of my patients / unless the law obliges me to. / I shall maintain / my theoretical and practical knowledge /at a high level./ I shall never use my knowledge / for activities that are contrary / to the ethical code of pharmacists. / I shall use my knowledge/ only for the defence / and restoration of health / of my fellow humans. / I shall do my best / to promote the science of pharmacy/ and keep the good name / of the University of Szeged. / I take this oath solemnly / and of my own free will.