Danubius Hotel Flamenco, Budapest, Hungary

Contributors

Hungarian Dietetic Association

Association of Hungarian Physiotherapists

Hungarian Society of Sports Medicine

Hungarian Psychiatric Association

Sponsors

Exhibitors DAY Medical Magyarország Kft. Ellman Magyarország Kft. Elsevier B.V. HYD LLC. Mediwel Kft.

Hungarian Society of Sport Science

Hungarian Pediatric Association

OBESITOLOGIA HUNGARICA

From basic science to clinical practice 5th Central European Congress on Obesity XXIII. Annual Congress of the Hungarian Society for the Study of Obesity

1-3 October 2015 Danubius Hotel Flamenco, Budapest, Hungary

Imprint RESPONSIBLE PUBLISHER Hungarian Society for the Study of Obesity Dr. Halmy Lászlóné SEAT OF PUBLISHER Boróka u. 9., H-1025 Budapest RESPONSIBLE EDITOR Dr. Halmy Lászlóné GRAPHIC DESIGN AND MAKE UP Mithos Műhely Kft., Kósik Krisztina RESPONSIBLE PRESS FOLPRESS Nyomdaipari Kft., Várlaki Imre ISSN 1586-7935

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2015; (14) Supplementum 2; S1-S92 Contact for scientific and program issues Eszter Halmy E-mail: [email protected] Congress secretariat Asszisztencia Congress Bureau Szent István krt. 7. H-1055 Budapest, Hungary Phone: +36 1 350 1854 Fax: +36 1 350 0929 E-mail: [email protected] Venue Danubius Hotel Flamenco Tas vezér u. 3-7., H-1113 Budapest, Hungary Access by public transportation The venue is near Móricz Zsigmond körtér station of the green underground line (M4) and tram line 6. Social programs Welcome Reception Thursday, 1 October 2015 | 20:30-22:00 Registered participants of the congress are welcome to take part at the Welcome Reception that will be held at the congress venue. The reception is included in the registration fee, extra ticket for non registered participants can be bought on-site upon availability. Gala Dinner Friday, 2 October 2015 | 20.30–24:00



Gala Dinner will be organized in BorLaBor Restaurant (www.borlaboretterem.hu, H-1053 Budapest, Veres Pálné u. 7.). Shuttle busses will leave 20:00 from the hotel. Please have your ticket with you to board busses. Ticket is 30 EUR/person. Please contact the onsite registration desk for available tickets.

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OBESITOLOGIA HUNGARICA Main Patron Zsófia Pusztai Head of WHO Country Office for Hungary Patron András Székács EFSA Management Board, member Chair of the Congress Eszter Halmy Co-Chair of the Congress Csaba Nyakas Chair of the Scientific Committee Péter Jákó Chair of the Organizing Committee Emese Antal International Scientific Committee Ketevan Asatiani Ľubomíra Fábryová Martin Fried Vojtěch Hainer Svetoslav Handjiev Jan Kopecky Boris Krahulec Marie Kunesova Dana Müllerova Magdalena Olszanecka-Glinianowicz Gabriela Roman Local Scientific and Organizing Committee András Falus Tamás Forster Zoltán Karádi Jenő Major Éva Martos Dénes Molnár József Pucsok Imre Rurik Tamás Tóth Ferenc Túry 5

2015; (14) Supplementum 2; S1-S92

Dear Colleagues, geographical position in the largely inland countries of the continent with a number of unique and common cultural and economic needs. We believe that the regional congress is supportive in that line of necessities.

The growing epidemic of overweight and obesity incur significantly increased medical costs for the healthcare systems worldwide and decrease the quality of life for the individuals. The increasing incidence and increasing degree of excess weight at the same time require multidisciplinary approach and global strategies. Isolated initiatives have had no results so far.

Due to the one hundred and thirtyfive presentations from 31 countries submitted within the framework of the current 5th Central European Congress on Obesity several new researches enrich our knowledge and professional opinions can also be exchanged in friendly conversations on the topic of obesity, which is one of the main, or even the greatest challenge for health care systems in our century.

The life-style, the physical, chemical, biological and socioeconomic environmental factors are playing significant roles in the growing epidemic. There is no effective medication for obesity. Metabolic and bariatric surgery shows plenty of results but not sufficient in fighting against the increasing prevalence. The prevention of overweight and obesity is becoming more valuable in preobese conditions and especially in childhood. The trends of obesity immediately need measures for solutions. The time has come when a wide social collaboration is needed above and beyond healthcare systems.

The Congress is held in memoriam Professor László Halmy DMSc, founder and president for life of the Hungarian Society for the Study of Obesity whose scientific achievements ranged from basic research to clinical management of obesity.

I hope the 5th Central European Congress on Obesity provides an excellent forum where in this spirit and with the full spectrum of obesitology we strive to introduce and discuss the latest results of international research in order to encourage development of regional scientific cooperation and to draw the attention of decisionmakers to form a consensus in the restraint of this epidemy. I also hope the meeting will provide a forum for the coordination of the different areas of actions as well.

Eszter Halmy MSc PhDf, Chair of the Congress

The original idea leading to the foundation of the Central European Regional Congresses was initiated by Professor László Halmy at the 15th European Congress on Obesity in 2007 in Budapest and was supported by the Czech colleagues, who took the lead by organising the 1st Central European Congress on Obesity in Karlovy Vary in 2008. Following the first event, Budapest gave home to the 2nd Central European Congress on Obesity entitled ’Quo Vadis, Obesitology?’ in 2009. Continuing the tradition, the 3rd Central European Congress on Obesity took place in Olsztyn, Poland in 2011. The 4th Central European Congress on Obesity was organised by the Romanian colleagues in Cluj Napoca in 2013. The Central European region possesses a special

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The national founder of obesity research was born 80 years ago Eszter Halmy, László Gyula Halmy Hungarian Society for the Study of Obesity Professor László Halmy MD PhD DMSc, the founding and life president of the Hungarian Society for the Study of Obesity was born on 21 May 1935 in Budapest. After living a very active and versatile life full of great scientific and human achievements, he passed away on 11 April 2013.

those who examined first visceral and subcutan fat with computer tomography for further research in the 1990s and carried out comparative diagnostic examinations to implement CT, MRI and bio-impedance in practice. He justified the significance of the waist circumference to height index in developing hypertension and he suggested using it to assess risk factors instead of BMI (2007). Of the comorbidities of obesity, in the 2000s new scientific achievements were primarily reached in hypertension, lipid metabolism, fat liver, sleep apnoe, cardiovascular and rheumatic diseases and the medical water for internal use as well as drinking cures in obesity and in balneology. He conducted the first longitudinal research in epidemiology in Hungary on approximately 800 overweight or obese patients (BMI≥27 kg/m²) for 10 years who were treated for comorbidities from the end of the 1960s. In these examinations he drew attention to the importance of obesity in comorbidities and the set-point theory. Between 1998 and 2002 his repetitive annual epidemiological examinations on 20 000 persons for five years showed 1.1% increase yearly in the prevalence of overweight and obesity. His name is linked with the consensus conferences on obesity from 1998, the first official guideline (2002) and its updated versions on the diagnostics and treatment of obesity and also the first cost estimates on the domestic ’price’ of the consequences of obesity (1998). From 1999 he called attention to the importance of weight maintenance, the necessity of the adequate and well-organized therapy of obesity, the involvement of the general practitioners’ network and such national prevention programs. After the 15th European Congress on Obesity in Budapest, 2008 became the Year of Obesity in Hungary. He conducted several scientific examinations on inpatients and outpatients including the conservative treatment of a great number of morbid obese. He was also active in creating the lifestyle therapy in obesity, trying out several medicines and examining the efficiency of medications. By examining 72.000 lipid parameters he proved that morbid obesity is not only a more intense form of gaining weight, rather, it should be considered as a separate

He was specialised in Internal Medicine, Tropical Diseases, Hypertension, Lipidology, Public Administration, and held a European SCOPE Fellowship (European Association for the Study of Obesity). His scientific areas include obesitology, endocrinology, hepatology, neuroendocrinology, hypertension, lipidology and epidemiology. He published 592 presentations and 430 publications, 45 articles are in PubMed. His index of citation is 108 and his impact factor is 11.366. The list of publication is available from: http://www.laszlo.halmy.hu/CVPublications Professor László Halmy published 26 scientific publications related to obesity at the start of his researching career in endocrinology between 1967 and 1990. Due to this scientific direction of his, his name is linked with the foundation of obesity scientific area and the scientific society in Hungary (1991-1992). As an internist, he dealt with the entire spectrum of obesity and its comorbidities and also he had significant achievements in the epidemiology, diagnosis and treatment of obesity, the prevalence of obesity and hypertension and examining visceral obesity as the primary cause for comorbidities. He wrote his academic dissertation (1984) on this topic entitled ‘The origins and medical treatment of obesity’. In this work he examined the neuroendocrine regulation of obesity in his experimental studies and also he clinically studied the prevalence of obestity in comorbid conditions, the concentration of bile acids and the changes in the sympathetic nervous system, DHA-activity as well as the hormone changes in fasting cures and two-phase slimming diets. He was one of

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board of the Hungarian Society of Hypertension (1992). In addition to holding several posts in Hungarian scientific committees, professional bodies and boards, he also became a member of the New York Academy of Sciences (1992) and a medical supervisor for UN UNTAC mission in Cambodia (1992).

disease. As a Hungarian record, he treated a female patient of approximately 400 kg aged 42 within one and a half years’ stay in hospital who reached 115 kg by conservative therapy, nutrient additives and the medical treatment of comorbidities. After his examinations on civil servants he was the first to examine the nutrition of the obese in Hungary and directed attention to the lack of vitamin, mineral and trace element intake and also suggested the necessity of supplements. He also examined from 1990s the effects of certain supplements in slimming cures in hospitals. He worked out a complex exercise program for inpatients. Moreover, he also dealt with the genetic background of obesity and the interaction of the genes and the environment. In his final scientific presentation, again as one of the pioneers he drew attention to the role of endocrine disruptors in chronic diseases (2012) and his final monography is about the significance of drinking cures in internal diseases (2013). In addition to his scientific activities he directed the attention of the healthcare professionals and the public to the importance of obesity and the necessity of reducing this growing epidemic by means of his more than 500 media coverages.

He became a member of the board of several scientific societies such as the Hungarian Society of Cardiology, the Hungarian Society of Endocrinology and Metabolism, the Hungarian Society of Hypertension, the Hungarian Society of Sport Medicine, the Hungarian Society for the Study of Obesity, the Hungarian Scientific Society of Law Enforcement, the Hungarian Association of Balneology and the honorary member of the National Association of Hungarian Dietitians and the Bulgarian Association for the Study of Obesity and Related Diseases. He was awarded with the title of Medical Brigadier General (2005) by the President of the State, the Ministerial Dagger of Honour for Scientific Research (2005) and the Medal for Scientific Research and Organisation (2004). He also held the Golden Ring of the Republic (1995). He received a 10-year Medal for Service (1982), a 15-year Medal for Service (1990), a 12-year Medal for Service (1990), a 25-year Medal for Service (1997) and a 30-year Medal for Service (2002.) He held the title of Excellent Immigration Officer in 1973 followed by the Golden Medal of Public Security (1979) and the Medal for the Service of the State (1981).

Having a look at his professional functions, he became a member of the Hungarian Collegium of Internal Medicine (2011), president of the 2nd Central European Congress on Obesity (2009), the national leader of SCOUT (20072010), president of Metabolism Club, Aesculap Academy (2008-2010), chair of the 15th European Congress on Obesity (2007), member of the directory board of the Hungarian Association of Balneology (2007), leader of Obesity Group of National Cardiovascular Prevention Program (2006), member of directory board of the Hungarian Scientific Society of Law Enforcement (20042007), member of Directory Board and Working Group on Metabolism of the Hungarian Society of Cardiology (2003) , member of the Scientific Committee of the Ministry of Interior (2001-2006), president of the Healthcare Section (2001-2006), editor-in-chief of Obesitologia Hungarica (2000), founder of the Hungarian Society for the Study of Obesity (1999), member of the Inter-ministerial Committee for Chemical Safety (1997-1999), president of the Social Insurance Health Insurance Self-Government (1996-1997), member of the directory board of the Social Insurance Health Insurance Self-Government (1995-1996), member of the Controlling Board of the Social Insurance Health Insurance Self-Government (1994-1995), the founder of Scientific Society of Social Insurance (1995-2007), the member of the directory board, Hungarian Society of Nutrition (1994-2000), the member of the Nutritional Forum (1993), the founder of the Hungarian Foundation Against of Obesity (1992) and member of the directory

Apart from his professional achievements, he also had several civilian medals and prizes such as ’Professional Award for excellent social responsibility’ posthumus in 2014 granted by The comprehensive health tests program of Hungary 2010-2020, ’For Szada’ posthumus honorary citizenship granted by the Local Government of Szada (2013), the Professional Award for Outstanding Social Responsibility (2012), László Mosonyi Award (2012), Award for Healthy Life (2012), Bezerédi Award, Golden grade (2009), József Soós Medal (2009), Oeuvre Prize, Hungarian Society for the Study of Obesity (2005), Pro Universitate et Scientia (2005), Ferenc Tangl Medal (2000), Medal from Primary Prevention Forum (1999), Memorial Plaquette of St. Kristóf (1996), Award for Peace-keeping, UN Police Mission in Cambodia (1995), István Kibédi Mátyus Plaquette (1993), Markusovszky diploma (1975), Silver Grade for Red Cross Activities (1963) and the First prize-winner of Kalokagathia Award for good student good sportsman (Kossuth High Shool) (1952). He founded and developed new scientific programmes and organisations and undertook the education of 28

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leaders, heads of hospital or ministry departments, chiefs of Health Care Services and international researchers. He laid the foundations of the concept and science of obesitology. He organised 62 congresses and conferences, conference meetings in the field of obesity and several more in other sciences. He established a scientific journal, defined professional protocols, organised national epidemiology programs and cooperated with a national club network on obesity. He also dealt with disseminating scientific information and advising in two national communication programs on health care. In the organisation of epidemiological study, he analysed the medical records of approximately 20.000 professionals between 1997 and 2002, organised the screening of the personnel of the Ministry of Interior and analysed the data of the 2001 physical survey of the professionals (2002) as well as the medical records of the professional staff from 2002 and 2003 (2004). He initiated medical scientific research and its organisational form in the Services of Law Enforcement and conducted the Hungarian Policemen’s Study for the regular health control of the personnel of the organisations of the Ministry of Interior and established the Hungarian Fit Policemen Study for regular screening of the personnel of the Police and a complex screening program for the staff of the Ministry of Interior (ophthalmology, orthopaedics, osteoporosis, hypertension, body composition, glucose tolerance). He analysed 72.265 serum lipid values. He carried out a 10-year retrospective study of the personnel of the Police Headquarters in Budapest (1980), directed the medical screening in the police headquarters (1980), and initiated the physical and psychological screening of the professional staff and the medical scientific research and its organisational form in the Services of Law Enforcement. He developed the Department of Cardiology, Metabolism and Rheumatology (1990), a radio-and enzyme immuno-assay laboratory (1973-84), thin layer chromatography (1968-1972), the National Program Central Research Group (1970) and a steroid chemistry laboratory (1968).

1984-1988). At an earlier stage of his life he served as the head of the 1st Medical Department of Otto Korvin Hospital of the Ministry of Interior (1972-1984). He was an assistant professor at the 4th Department of Medicine at the Postgraduate Medical Institute (19711972) and a scholarship holder from the Hungarian Academy of Sciences (1968-1971). He started his career as an assistant at the 4th Department of Medicine in the Postgraduate Medical Institute (1961-1968). In the area of scientific education he acted as the thesis advisor for 5 PhD students and a PhD program leader of Semmelweis Medical University. He was responsible for educating medical students (1973-1983) and dietitians (1974-1983). In 1982 he was awarded with the title of honorary professor and in 1976 as honorary assistant professor. He became a doctor of medical sciences (DMSc) at the Hungarian Academy of Sciences in 1986 and completed his PhD at the Hungarian Academy of Sciences in 1972. He graduated from the School of Medicine of the Medical University, Budapest in 1959.

Regarding his places of work, he was the medical director of Platon Health Advising and Services Ltd. (2007-2013) and the leader of the Cardiometabolic Centre (20062007). He worked for the Division of Hypertension and Lipid Metabolism Disorders at the Central Hospital of the Ministry of Interior (2003-2007) and acted as a head of division and coordinator of Epidemiologic Survey. He was the head of the Department of Medical Coordination (1999-2003) and the director of Medical Service (1997-1999). He headed the 5th Department of Internal Medicine of the Central Hospital of the Ministry of Interior (1989-1997). He also worked as a visiting professor at Black Lion Hospital in Addis Ababa (Ethiopia,

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2015; (14) Supplementum 2; S1-S92 Program Thursday | 1 October 2015

16:10-16:30 Coffee break

11:30-19:00 Onsite registration

16:30-18:00

13:00-13:30 Welcome snack 13:30-14:00

Opening Ceremony Welcome messages by Eszter Halmy Acting President of Hungarian Society for the Study of Obesity Chair of the Congress



Zsófia Pusztai Head of WHO Country Office for Hungary Patron of the Congress



Handing over honorary diplomas and medals Eszter Halmy Acting President of HSSO Péter Jákó Honorary President of HSSO

14:00-14:30 Genetics and epigenetics of obesity Chairs: Eszter Halmy, Csaba Nyakas 14:00-14:30 Genetics and epigenetics of obesity András Falus (Hungary) A-0113 14:30-16:10 From Basic Science to Clinical Practice In memoriam Professor László Halmy Chairs: Péter Jákó, József Pucsok 14:30-14:50 Take a walk with the Finntwins: What do the Finntwins tell about the causes and consequences of obesity? Aila Rissanen (Finland) A-0109 14:50-15:05 History of obesity research in Hungary: a tribute for the founder Csaba Nyakas (Hungary) A-0141 15:05-15:20 Metabolically healthy obesity: Does it exist? Vojtěch Hainer (Czech Republic) A-0094 15:20-15:35 Obesity management dilema: Should we focus on body composition or general health? Constantine Tsigos (Greece) A-0099 15:35-15:50 Effective methods of weight maintenance and weight reduction in differently financed weight management programs Eszter Halmy (Hungary) A-0142 15:50-16:05 Overweight, obesity and underweight prevalence in 7 years old children in the Czech Republic since 1951 Marie Kunešová, Bohuslav Procházka, Jana Vignerová, Jana Pařízková, Radka Braunerová, Markéta Mádlová, Jitka Riedlová, Hana Zamrazilová, Martin Hill, Alena Šteflová (Czech Republic) A-0096

Central regulation of energy balance, hunger and satiety Symposium organizer: Zoltán Karádi Chairs: Takashi Kondoh, Wolfgang Langhans

16:30-16:45 Health-related functions of died bonito dashi (A traditional Japanese fish stock) Takashi Kondoh, Tetsuro Matsunaga, Yoichi Ueta, Hisao Nishijo (Japan) A-0106 16:45-17:00 Role of peripheral GLP-1 in energy homeostasis and glycemic control Wolfgang Langhans, Jean-Philippe Krieger, Myrtha Arnold, Pius Lossel, Klaus G. Pettersen, Shin J. Lee (Switzerland) A-0105 17:00-17:15 Obesity induces resistance to anorexigenic peptides in rats Miklós Székely, Szilvia Soós, Márta Balaskó, Erika Pétervári (Hungary) A-0052 17:15-17:30 Effects of intraamygdaloid microinjections of RFamide-related peptides (RFRPs) on food intake in rats László Lénárd, Olga Zagoracz, Kristóf László, Tamás Ollmann, László Péczely, Rita Gálosi, Anita Kovács (Hungary) A-0061 17:30-17:45 Complex functional attributes of orbitofrontal cortical glucose monitoring neurons István Szabó, Edina Hormay, Bettina Csetényi, Viktor Torda, Mátyás Tóth, Zoltán Karádi (Hungary) A-0090 17:45-18:00 Discussion 18:00-18:45 Animal models in obesity research Chairs: Jan Kopecky, Csaba Nyakas 18:00-18:15 Healthy adipocyte Jan Kopecky (Czech Republic) A-0103 18:15-18:23 Omega 3 fatty acids augment beneficial effects of calorie restriction in mice – induction of the futile substrate cycling in white fat. Pavel Flachs, Ralph Ruhl, Petr Zouhar, Michaela Svobodova, Petra Janovska, Kristina Bardova, Jan Kopecky (Czech Republic) A-0116 18:23-18:31 INTERACTION BETWEEN HIGH VS. LOW CALORIE INTAKE AND PHYSICAL EXERCISE ON COGNITION IN RATS Klára Felszeghy, Anikó Pósa, Csaba Varga, Csaba Nyakas (Hungary) A-0057 18:31-18:45 Discussion

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OBESITOLOGIA HUNGARICA 18:45-19:00 Exercise Break with Hydratation

Friday | 2 October 2015

19:00-20:25 Diagnosis, Prevalence and Costs of Obesity Chairs: Magdalena Olszanecka-Glinianowicz, Imre Rurik

07:00-20:00 Onsite registration

19:00-19:08 Risk of diabetes in combined metabolic abnormalities and body mass index categories Mohsen Janghorbani, Nouredin Soltanian, Bijan Iraj (Iran) A-0010 19:08-19:16 Lean mass and fat mass distribution in Ukrainian postmenopausal women with abdominal obesity and metabolic syndrome Vladyslav Povoroznyuk, Larysa Martynyuk, Nataliia Dzerovych, Lilya Martyntyuk (Ukraine) A-0039 19:16-19:24 Bone mineral density and trabecular bone score in Ukrainian women with obesity Vladyslav Povoroznyuk, Nataliia Dzerovych, Larysa Martynyuk, Tetiana Kovtun (Ukraine) A-0040 19:24-19:32 25-hydroxyvitamin D3 concentration and profile of selected adipokines in type 2 diabetic patients with excessive body weight Joanna Kocot, Małgorzata Kiełczykowska, Irena Musik, Piotr Dziemidok, Grzegorz Szcześniak, Jacek Kurzepa (Poland) A-0084 19:32-19:40 Prevalence of physiological risk factors among Kazakhs and Russians in Kazakhstan Toregeldy Sharmanov, Shamil Tazhibayev, Oksana Dolmatova, Baurzhan Zhussupov, Ayan Yergaliyeva, Altyn Sarsembayeva, Zhanar Tolysbayeva (Kazakhstan) A-0013 19:40-19:48 The association between body mass index and health outcomes in Italy Marco DiBonaventura, Henrik Meincke, Janine Fournier, Alessandro Forlin, Caroline Kaas Kristiansen (USA) A-0068 19:48-19:56 The association between body mass index and health outcomes in Germany Marco DiBonaventura, Henrik Meincke, Janine Fournier, Alessandro Forlin, Caroline Kaas Kristiansen, Lisa Seitz (USA) A-0069 19:56-20:09 Prevalence and economic burden of obesity in Hungary Imre Rurik, Gabriella Iski, Péter Torzsa, Csaba Móczár, Judit Szidor, Tímea Ungvári, János Sándor (Hungary) A-0087 20:09-20:25 Discussion 20:30-22:00 Welcome Reception

07:30-08:00 Brisk walking with Attila Katus 08:30-09:55 Policy and Prevention strategies Chairs: Éva Martos, Aila Rissanen 08:30-08:50 Hungarian policy measu es in the field of nutrition Éva Martos (Hungary) A-0123 08:50-09:05 Nutritional status and physical activity of the Hungarian adult population - Hungarian diet and nutritional status survey (OTÁP2014) Barbara Nagy, Éva Martos, Márta Bakacs, Eszter Sarkadi Nagy, Erzsébet Schreiberné Molnár (Hungary) A-0124 09:05-09:20 Czech National Actionplan Fighting Obesity -Health 2020 D. Mullerova, M. Fried, M. Haluzík, H. Janatová, M. Kunešová, T. Pelikánová, J. Rážová, Š. Svačina, A. Šteflová (Czech Republic) A-0097 09:20-09:35 Contribution to the prevention of obesity - „School for health” Svetoslav Handjiev, Aneliya Kuzeva, Teodora Handjieva-Darlenska (Bulgaria) A-0012 09:35-09:50 Possibilities and barriers of obesity management within the healthcare system in Hungary Eszter Halmy (Hungary) A-0146 09:50-09:55 Discussion 09:55-11:15

Community based programs to prevent childhood obesity and reduce health inequities, EPODE experience Chair: Jean-Michel Borys

09:55-10:10 EPODE Methodology: Community based intervention approaches to prevent childhood obesity and decrease health inequities Jean Michel Borys (France) A-0140 10:10-10:25 “PETICA – play for health” – childhood obesity prevention programme in Croatia Darija Vranesic Bender (Croatia) A-0147 10:25-10:40 Kindergarten – A Nucleus of CBI in the Prevention of Childhood Obesity (The SALTO Project) Susanne Ring-Dimitriou (Austria) A-0122

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2015; (14) Supplementum 2; S1-S92 10:40-10:55 GYERE program - Preventing childhood obesity by using the EPODE model in Hungary Zsuzsanna Szűcs, Jolán Kubányi, Szilvia Szigetvári (Hungary) A-0112 10:55-11:15 Discussion 11:15-11:35 Coffee break & Poster discussion 1

13:07-13:15 The relationship between obesity and microalbuminuria in children Aliz Szommer, Éva Kovács, Dénes Molnár (Hungary) A-0085 13:15-13:25 Discussion 13:25-14:15 Lunch break & Poster discussion 2

11:35-13:25 Childhood Obesity Chairs: Dénes Molnár, Maia Konstantinova

14:15-16:00 Obesity as a Gateway Disease Chairs: Tamás Forster, Constantine Tsigos

11:35-11:50 Metabolic syndrome in young children: definitions and results of the IDEFICS study Dénes Molnár (Hungary) A-0104 11:50-12:05 Indicators for assessment of cardio metabolic risk in children aged 7-18 years Maia Konstantinova M, Lalka Rangelova, Stefka Petrova, Veselka Duleva, Daniela Bojilova, Radka Savova, Margarita Arshinkova (Bulgaria) A-0066 12:05-12:20 Changes in subcutaneous adipose tissue distribution, plasma lipids, leptin, lipid peroxidation and fatty liver index in obese children and adolescents of the MODUL study Brigitte M. Winklhofer-Roob, Ines Pamperl, Eva Hütter, Martina Kandlbauer, Gernot Faustmann, Beate Tiran, Gholamali Khoschsorur, Andreas Meinitzer, Ulrike Fasching, Elisabeth Stöcklin, Peter Weber (Austria) A-0128 12:20-12:35 Childhood obesity and endocrine disorders – causes versus consequences Agnieszka Zachurzok (Poland) A-0072 12:35-12:43 Prevention of childhood obesity Éva Kovács, Dénes Molnár (Hungary) A-0086 12:43-12:51 24-hour blood pressure monitoring in obese children and adolescents Katarína Prochotská, László Kovács, Janusz Feber (Slovakia) A-0067 12:51-12:59 Non-invasive assessment of the arterial function in overweight and obes children and adolescents Erzsébet Valéria Hidvégi, Miklós Illyés, Attila Cziráki (Hungary) A-0037 12:59-13:07 Multiple-component care in lifestyle change is effective to decrease adolescent obesity Bernadett Heintz, Erika Medveczky, Valéria E. Fekete, Csaba Nyakas (Hungary) A-0079

14:15-14:30 Obesity and female infertility Magdalena Olszanecka-Glinianowicz (Poland) A-0100 14:30-14:45 Relationship of central obesity to cardiovascular risk Tamás Forster (Hungary) A-0121 14:45-15:00 Immunological aspects of obesity György Paragh, Péter Koncsos, Péter Fülöp (Hungary) A-0129 15:00-15:15 Lipid metabolism in obesity Albert Császár (Hungary) A-0139 15:15-15:30 Non alcoholic fatty liver disease Tatjana Ábel, Gabriella Lengyel (Hungary) A-0119 15:30-15:45 Obesity in endocrinology Zsuzsanna Valkusz (Hungary) A-013 15:45-16:00 Discussion 16:00-16:15 Exercise Break with Hydratation 16:15-17:55 Clinical aspects of obesity and co-morbidities Chairs: Marie Kunesova, Volkan Demirhan Yumuk 16:15-16:30 MicroRNA regulation of the inflammatory cytokines in adypocytes Károly Cseh (Hungary) A-0136 16:30-16:45 Lipids and the size of lipoprotein particles in newly diagnosed naive overweight/obese type 2 diabetic patients Ľ. Fábryová, A. Dukát, S. Oravec (Slovakia) A-0102 16:45-16:53 Comparative efficiency of aldosterone blockers in the complex therapy of resistant arterial hypertension in obese patients and patients with normal body mass M. T. Vatutin, A. M. Shevelok, G. E. Degtiarova (Ukraine) A-0008

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OBESITOLOGIA HUNGARICA 16:53-17:01 Thyroid pathologies in obese patients with normal thyroid functions Feray Akbas, Hanife Usta Atmaca, Fettah Sametoglu, Mustafa Boz, Mutlu Niyazoglu (Turkey) A-0016 17:01-17:09 Cigarette smoking and asymptomatic diastolic dysfunction in metabolically healthy obese patients Feray Akbas, Hanife Usta Atmaca, Fettah Sametoglu, Ilker Nihat Okten, Yasin Yuksel, Mustafa Boz (Turkey) A-0017 17:09-17:17 The role of stress management in weight control Edit Czeglédi (Hungary) A-0003 17:17-17:25 A high protein diet and isometric exercises decrease visceral fat in ER+ breast cancer patients on Tamoxifen Diana V. Artene, Cristian I. Bordea, Alexandru Blidaru (Romania) A-0092 17:25-17:40 Effect of subnormal level of deuterium on glucose tolerance, serum HDL- and Na+-concentration Gábor Somlyai, Miklós Molnár, Ildikó Somlyai, István Fórizs, György Czuppon, Orsolya Abonyi (Hungary) A-0120

19:15-19:23 Laparoscopic Gastric Plication and its impact on body composition, lipid and glucose metabloism Pavol Holéczy, Marek Bužga, Zdeněk Švagera (Slovakia) A-0045 19:23-19:31 The effect of diet on weight loss after gastrointestinal surgery Edit Somogyi, Zita Dobák, Csaba Nyakas, †HS Koopmans (Hungary) A-0073 19:31-19:39 Single centre results and experiences after 405 laparoscopic Roux-en-Y gastric bypass and 38 laparoscopic gastric sleeve resections performed in Hungary between 2010 and 2015 Elemér Mohos, Gábor Tornai, Gábor Sándor, Petra Mohos, Tibor Nagy (Hungary) A-0127 19:23-19:31 The effect of diet on weight loss after gastrointestinal surgery Edit Somogyi, Zita Dobák, Csaba Nyakas, †HS Koopmans (Hungary) A-0073 19:39-19:50 Discussion 20:00

20:30-24:00 Gala Dinner Informal Round-table Meeting during the dinner

17:40-17:55 Discussion 17:55-18:15 Coffee break & Poster discussion 3 18:15-18:45 Metabolic and bariatric surgery in obesity Chairs: Róbert Tamás, Ketevan Asatiani 18:15-18:45

Shuttle bus for Gala Dinner

Bariatric and metabolic surgery – Current status Martin Fried (Czech Republic) A-0093

18:45-19:50 Metabolic and bariatric surgery Chairs: Martin Fried, Elemér Mohos 18:45-19:00 Postbariatric surgery medical follow up Volkan Demirhan Yumuk (Turkey) A-0110 19:00-19:15 Fatty acid composition of adipose triglycerides in obese diabetic women after bariatric surgery: 2 year follow up Marie Kunešová, Barbora Sedláčková, Olga Bradnová, Eva Tvrzická, Barbora Staňková, Petra Šrámková, Karin Doležalová, Pavla Kalousková, Petr Hlavatý, Martin Hill, Martin Fried, Vojtěch Hainer, Jana Vrbiková (Czech Republic) A-0095

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2015; (14) Supplementum 2; S1-S92 Saturday | 3 October 2015 07:00-15:00 Onsite registration 07:30-08:00 Brisk walking with Attila Katus 08:30-09:00 Media messages and disordered eating Chairs: Vojtěch Hainer, Tamás Tóth 08:30-09:00 Media messages and disordered eating Attila Forgács (Hungary) A-0132 09:00-09:50 Genes, environment interactions in modern societies Chairs: Dana Müllerova, Károly Cseh 09:00-09:08 DDE effect on adipogenesis M. Pesta, D. Mullerova, J. Dvorakova, M. Cedikova, P. Dvorak, V. Kulda, V. Babuska, M. Kralickova, J. Kuncova (Czech Republic) A-0098 09:08-09:16 Strong sex-specific additive effect of the NYD-SP18 and FTO variants on the BMI values Jaroslav A. Hubacek, Dana Dlouha, Vera Lanska, Vera Adamkova (Czech Republic) A-0005 09:16-09:24 Afamin, a potential marker of increased risk for metabolic syndrome, is strongly associated with hepatic lipid accumulation Timea Kurdiova, Vitazoslav Belan, Ramona Berberich, Daniela Gasperikova, Gerd Schmitz, Hans Dieplinger, Barbara Ukropcova, Jozef Ukropec (Slovakia) A-0044 09:24-09:32 The way of treatment the obesity patients by the computerized fragmentary images in the Internet Vlastopulo Vladyslav (Germany) A-0047 09:32-09:40 New method of weight loss by acupuncture tourmaline vibrational exposure for general population Vladyslav Vlastopulo (Germany) A-0049 09:40-09:50 Discussion 09:50-10:40 Psychological aspects of obesity Chairs: Svetoslav Handjiev, Dóra Perczel Forintos 09:50-09:58 Preventing overweight and obesity: Management vs leadership Arash Rashidi, Azadeh Davari (Iran) A-0004 09:58-10:06 Obesity and the workplace: the hidden case of nurses Luciana Torquati, Tracy Kolbe-Alexander, Christina Persson, Toby Pavey, Michael Leveritt (Australia) A-0064

10:06-10:14 Nutritional and metabolic status in adolescents with anorexia nervosa Andrey Zubovich, Elena Pavlovskaya, Tatyana Strokova, Olga Kuzmicheva (Russia) A-0031 10:14-10:34 Multilevel psychological approaches to weight control Dóra Perczel-Forintos (Hungary) A-0138 10:34-10:40 Discussion 10:40-11:00 Coffee break 11:00-13:10

Nutritional Science Symposium Organised by the Hungarian Dietetic Association Chairs: György Bíró, Endre Máthé

11:00-11:20 Human appetite for sweetness and weight management: a focus on recent data illustrating the role of low-energy sweeteners France Bellisle (France) A-0134 11:20-11:33 The connection between energy balance and hydration Emese Antal (Hungary) A-0115 11:33-11:46 Eating habits of our ancestors in the light of archaeobotanical remains Ferenc Gyulai (Hungary) A-0133 11:46-11:59 The soil nutrient status and mineral content of winter wheat grains in Hungary Zoltán Győri (Hungary) A-0137 11:59-12:12 Main problems in the dietary habits of children aged 4-10 Bernadett Kiss-Tóth (Hungary) A-0043 12:12-12:25 Overweight, obesity, other cardiovascular risk factors and vitamin D deficiency in school children with high risk family history Tamás Szamosi, Patricia Göltl, Dóra Török, András Szabó (Hungary) A-0078 12:25-12:38 Deeper knowledge - further questions. Microbiome and obesity Klára Tamássy (Hungary) A-0114 12:38-12:58 Achieving cellular homeostasis in multicellular organism: TOR pathway, mitochondrial dynamics, vitagenes and ageing Endre Máthé, Zsanett Zsvér-Vadas, Szabolcs Vígh (Hungary) A-0135

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OBESITOLOGIA HUNGARICA 12:58-13:10 Discussion 13:10-14:00 Salad Lunch by Eisberg 14:00-14:45 Nutrition, hydration, excercise in obesity Chairs: Lubomira Fabryova, Miklós Tóth 14:00-14:08 Professional collaboration, lifestyle changes and sustainable results in the field of weight reduction Ágnes Freiberg, Ilona Hegyi, Zsuzsanna Varga, Katalin Tóvizi, István Vasas (Hungary) A-0074 14:08-14:16 A survey on hydration and body composition among Italian young athletes Styven Tamburo, Stefania Pucciarelli, Valerio Napolioni, Massimo Nabissi, Nicola Sponsiello, Emilio Amadio, Rosita Gabbianelli (Italy) A-0080 14:16-14:24 Effects of 3-month aerobic-strength training on physical fitness and cognitive functions in seniors Patrik Krumpolec, Lucia Slobodova, Veronika Tirpakova, Matej Vajda, Silvia Vallova, Stanislav Sutovsky, Peter Valkovic, Milan Sedliak, Jozef Ukropec, Barbara Ukropcova (Slovakia) A-0036 14:24-14:32 Changes of brain derived neurotrophic factor in response to exercise in sedentary middle-aged and elderly individuals Denisa Maderova, Lucia Slobodova, Matej Vajda, Timea Kurdiova, Patrik Krumpolec, Silvia Vallova, Miroslav Balaz, Veronika Tirpakova, Ivan Jelok, Erika Zemkova, Dusan Hamar, Milan Sedliak, Barbara Ukropcova, Jozef Ukropec (Slovakia) A-0042 14:32-14:45 Discussion 14:45-15:15 Exercise is health Chairs: Eszter Halmy, Csaba Nyakas 14:45-15:15 Exercise is Health Miklós Tóth (Hungary) A-0144 15:15-15:25 Closing Invitation to 6th CECON

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2015; (14) Supplementum 2; S1-S92 Posters Discussions: Friday | 2 October 2015

13:25-14:15 Poster discussion 2

11:15-11:35 Poster discussion 1

National Institute of Surgery and Transplantatiology Andriy Lavryk, Olena Dmytrenko, Andriy Zgonnyk, Mykola Manoylo (Ukraine) A-0028

Association of metabolic syndrome with the cardio-ankle vascular index in asymptomatic Korean population Su-Hyun Nam, Sang-Wook Song, Sung-Goo Kang, Yun-Ah Lee (South Korea) A-0007 Cardiovascular risk in patients with hypertension on the background of morbid obesity and its medication, non medication and bariatric correction Anna Shkroba, Andrey Lavryk, Elena Mitchenko (Ukraine) A-0014 A success story in weight loss: You can do it without bariatric surgery or medication! Feray Akbas, Hanife Usta Atmaca, Fettah Sametoglu, Gokalp Avlagı (Turkey) A-0015 Relationship between nitric oxide and obesity in children Aleksandra Czumaj, Marta Śledzińska, Michał Brzeziński, Barbara Kamińska, Tomasz Śledziński (Poland) A-0021 Past and future trends in the prevalence of overweight and obesity in Lithuania Vilma Kriaucioniene, Janina Petkeviciene, Laura Webber (Lithuania) A-0022 Role of fractalkine/Cx3CR1 signaling in macrophage trafficing into adipose tissues and in the development of obesity Ágnes Polyák, Zsuzsanna Winkler, Szilamér Ferenczi, Dóra Kővári, Dániel Kuti, Krisztina J. Kovács (Hungary) A-0023 A study on the plantar pressure distribution among obese and non-obese participants Eleonóra Leidecker, Mónika Galambosné Tiszberger, Aliz Bohner-Beke, Bálint Molics, Melinda Járomi, János Kránicz (Hungary) A-0024 Only BMI is not enough for evaluation of nutritional state of professional soldiers in the Armed Forces of the Czech Republic Jana Fajfrová, Vladimír Pavlík, Miluše Vacková, Ondřej Blažek (Czech Republic) A-0025

Τhe issue of bulimic behavior over time: it’s a disease or a phenomenon of the modern era. Bulimia through the lens of scientific research Athanasia Antiochou (Greece) A-0029 Application of functional food at complex of rehabilitation measures in patients suffering from coronary heart disease with obesity K.D. Babov, A.L. Plakida, E.A. Usenko (Ukraine) A-0032 metabolic syndrome in patients with severe mental disorder: physical activity program from the nursing consultant in the mental health unit: first steps Maria del Carmen Vallejo Curto, Laura Jardón Golmar, María Blanco Formoso, Tania Rivera Baltanás, Jose Manuel Olivares Díez, Carlos Spuch Calvar (Spain) A-0033 Parental attitudes toward nutrition and physical activity and children’s food intake, physical activity, sedentary behaviour and body mass index Sanja Šumonja, Marija Jevtić (Serbia) A-0035 Preventissimo – Prevention of obesity and comorbidities with e-Health Éva Palik Dr., Judit Schmidt, Judit Kovács, Bernadett Kiss-Tóth, János Szlankó, Zoltán Nácsa (Hungary) A-0041 Obesity, type 2 diabetes and exercise modulate specific microRNAs in skeletal muscle & circulation Silvia Vallova, Miroslav Balaz, Timea Kurdiova, Marek Vician, Daniel Gasperikova, Iwar Klimes, Erika Zemkova, Dusan Hamar, Jozef Ukropec, Barbar Ukropcova (Slovakia) A-0046 Association of plasma aldosterone level with obesity in chronic heart failure with preserved ejection fraction Nykolay Vatutin, Anna Shevelok, Anna Degtyareva (Ukraine) A-0051

Nutritional state and physical fitness among civilian and military medical students Jana Fajfrová, Vladimír Pavlík, Ondřej Blažek, Miluše Vacková (Czech Republic) A-0026

Obesity-induced shift in the age-related alterations of Cholecystokinin effects Nóra Füredi, Hella Gebhardt, Alexandra Mikó, Szilvia Soós, Miklós Székely, Márta Balaskó, Erika Pétervári (Hungary) A-0053

Nutritional habits, physical activity and nutritional state of Czech military medical students Vladimír Pavlík, Jana Fajfrová, Miluše Vacková, Ondřej Blažek (Czech Republic) A-0027

The potential role of alarin, a novel peptide mediator in body weight regulation Alexandra Mikó, Patrik Kéringer, Nóra Füredi, Miklós Székely, Márta Balaskó, Susanne Brunner, Barbara Kofler, Erika Pétervári (Hungary) A-0054

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OBESITOLOGIA HUNGARICA Age-related shifts in the responsiveness to coricotropin-releasing factor concerning energy homeostasis Judit Tenk, Rebeka Pagáts, Ildikó Rostás, Szilvia Soós, Erika Pétervári, Miklós Székely, Márta Balaskó (Hungary) A-0055 Leptin in metabolic dysregulation: the influence of age and nutritional state Ildikó Rostás, Zsófia Csernela, Judit Tenk, Szilvia Soós, Erika Pétervári, Miklós Székely, Márta Balaskó (Hungary) A-0056 Prevalence of melanocortin-4 receptor gene mutations in Slovak obese children and adolescents Eva Vitáriušová, Emil Polák, Peter Celec , Zuzana Pribilincová, Ľudmila Košťálová, Anna Hlavatá, Ľudevít Kádasi, László Kovács (Slovakia) A-0058 Complex lifestyle program to prevent obesity in mothers with children of nursery age Tímea Téglás, Judit Boda-Ujlaky, Bernadett Heintz, Attila Novák, Zita Dobák, Éva Bagi, Csaba Nyakas (Hungary) A-0059 Learning related effects of satiety inducing RFamide-related peptides (RFRPs) in the amygdaloid body of rats Anita Kovács, Olga Zagoracz, Kristóf László, Tamás Ollmann, László Péczely, Rita Gálosi, László Lénárd (Hungary) A-0060 Feeding-related effects of intrahypothalamic administration of neuropeptide QRFP-26 in rats Olga Zagoracz, Anita Kovács, Kristóf László, László Lénárd (Hungary) A-0062 Dance therapy on prescription as stressmanagement Agnes Nagy, Gabriella Hegyi (Hungary) A-0063 Association of plasma lipids fatty acid composition with metabolic profile of Czech adolescents P. Hlavaty, E. Tvrzicka, B. Stankova, H. Zamrazilova, B. Sedlackova, L. Dusatkova, M. Kunesova (Czech Republic) A-0065 Identification of risk factors for Non communicable diseases among public sector office employees Hasinthi. Swarnamali, Thilini Jayasinghe, Prasad. Katulanda (Sri Lanka) A-0070 Development of nutritious, low cost and attractive food items for school canteens Hasinthi Swarnamali, Thilini Jayasinghe (Sri Lanka) A-0071 Obesity-induced shift in the age-related alterations of CCK Nóra Füredi, Hella Gebhardt, Alexandra Mikó, Szilvia Soós, Márta Balaskó, Miklós Székely, Erika Pétervári (Hungary) A-0075 Different ways of body composition measurements in rats Patrik Kéringer, Alexandra Mikó, Éva Tékus, Nóra Füredi, Márta Balaskó, Erika Pétervári (Hungary) A-0076

17:55-18:15 Poster discussion 3 Transition of nutrition style and obesity, a Kuwaiti case study Othman Saleh Al-Razgan (USA) A-0077 The Hungarian Aqua Promoting Programme in the Young (HAPPY) - A best practice, sustainable community-based intervention program in Hungary Barbara Nagy, Anita Varga, Viktória Anna Kovács, Gergő Erdei, Márta Bakacs, Éva Martos (Hungary) A-0126 National nutritional environment survey in schools, 2013 Gergő Erdei, Barbara Nagy, Márta Bakacs, Eszter Sarkadi Nagy, Anita Varga, Kinga Miháldy, Erzsébet Molnár Schreiberné, Éva Martos (Hungary) A-0125 Expression of PPAR-gamma during in vitro adipogenesis after exposure to some atypical antipsychotics Melinda Kolcsár, Zsolt Gáll, László Bába, Ünige Szabó, Ilka Bíró, Tamás Tábi, Éva Szökő, Imre Zoltán Kun (Romania) A-0118 Metabolic flexibility differences between obesity-resistant (A/J) and obesity-prone (C57BL/6J) mice Bardova K., Horakova O., Janovska P., Kus V., van Schothorst E., Hoevenaars F., Hensler M. Keijer J., Kopecky J. (Czech Republic) A-0117 Cingulate cortex IL-1β mediated mechanisms in the regulation of feeding and metabolism in the rat Bettina Csetényi, Edina Hormay, Bernadett Nagy, István Szabó, Mátyás Tóth, Viktor Torda, Zoltán Karádi (Hungary) A-0089 Glucose-monitoring neurons of the rat cingulate cortex: feeding and metabolic significance Edina Hormay, Bettina Csetényi, István Szabó, Bernadett Nagy, Viktor Torda, Mátyás Tóth, Zoltán Karádi (Hungary) A-0088 Sarcopenia and water exercise Márta Hock, Katalin Takács, Mária Figler, Erika Pétervári, Márta Balaskó, János Garai, József Bódis, Szilvia Soós (Hungary) A-0083 Relationships between fasting serum amylase and ghrelin, peptide YY3-36 levels in healthy men Young Jin Tak (South Korea) A-0082 Multiplex-PCR for the identification of cows’, goats’ and sheep’s milk in dairy products Wojciech Barszczewski, Ewa Walczak (Poland) A-0130

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2015; (14) Supplementum 2; S1-S92 ABSTRACTS A-0003 The role of stress management in weight control Edit Czeglédi Semmelweis University, Institute of Behavioural Sciences, Budapest, Hungary Life style (overeating and physical inactivity) is of great importance in the etiology of obesity. Psychological factors are often found in the background of life style. Chronic stress can influence both energy intake and energy expenditure. Besides, it can contribute to behaviors that hinder the keeping of a diet (e.g., irregular eating pattern, emotional eating). The evidence-based Williams LifeSkills stress management and communication skills development training consists of adaptive emotion-focused and problem-focused coping strategies and skills to improve relationships. The Williams LifeSkills program can be understood in and adapted to the context of obesity and weight management as well. The log-entry technique enhances the identification of emotions, thus emotional hunger and physiological hunger can be differentiated. With the help of the 4-question technique (situation analysis) the participant can decide upon a more adequate response. Acquiring deflection skills may be helpful in replacing emotional eating with other behaviors. Assertive communication can contribute to the effective management of conflicts that otherwise would result in binge eating due to the tension or distress. Developing skills to improve relationships (e.g., empathy) facilitates the development of positive, supportive interpersonal relationships. Successful weight management in the “toxic” environment that encourages obesity requires resistance to temptation and great efforts to keep the diet and regular physical exercise. Therefore saying No and the problem solving technique can be very useful for those fighting excess weight. The Williams LifeSkills program was adapted to the issue of obesity. The effectiveness study is being performed. Experiences gained from the first seven training groups (n=79, 91,1% women, the drop-out rate: 24,1%) will be presented. A-0004 Preventing overweight and obesity: Management vs leadership Arash Rashidi1, Azadeh Davari2 1 National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Iran; 2 School of Leadership and Education Sciences, University of San Diego, USA Leadership may be defined as a “shared influence process to achieve goals”. While the clinical nutrition

approaches to prevent obesity and overweight mainly focus on managing the condition, there is a big need for adopting leadership approaches among clients. The leadership process depends on shared visioning, alliance and motivation. These skills need high levels of emotional intelligence to be applied by clinical practitioners. In many cases, there is no common (shared) vision or agreed weight loss strategy between the nutrition practitioner and his/her client, nor is enough time spent for aligning and motivating the obese person. Practitioners are heavily trained for the technical aspects related to the management of disease. Different measurements, examining underlying causes of obesity, presence or absence of other health conditions, calculating energy requirements and expenditures, development of lowcalorie meal plans (by hand or using software), and probably some question and answers fill the counseling session. However, agreement on proper dietary strategy and creating and keeping the motivation of client shall be prioritized, if sustainable changes in behavior and weight are to be achieved. A-0005 Strong sex-specific additive effect of the NYD-SP18 and FTO variants on the BMI values Jaroslav A. Hubacek, Dana Dlouha, Vera Lanska, Vera Adamkova Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic Purpose: The role of the FTO gene in obesity development is well established in populations around the world. NYD-SP18 variant was suggested to have similar effect on BMI, but the role of this gene in BMI determination has not yet been verified. The objective of our study was to confirm he association between the NYDSP18 rs6971019 SNP with BMI in the Slavic population and further analyze i/ possible sex-specific effects of the NYD-SP18 on BMI and ii/ simultaneous effect of FTO rs17817449 and NYD-SP18 rs6971019 on BMI. Subjects: Adult population sample based on the postMONICA study (1,191 males and 1,368 females). Outcome Measures: BMI; FTO and NYD-SP18 polymorphisms have been genotyped using PCR-RFLP. Methods: Individuals have been examined three times within the 9 years; polymorphisms have been genotyped using PCR-RFLP. Results: Genotype frequencies in Czechs are similar to the other populations (FTO, GG – 18%, GT – 49%, TT

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OBESITOLOGIA HUNGARICA – 33%; NYD-SP18, AA – 53%, AG – 40%, GG – 7%). At first examination, NYD-SP18 rs6971019 SNP was related to BMI in males (2000/1 GG 28.3±3.7 kg/m2 vs. +A 27.5±3.7 kg/m2 P 1cm, 11 patients had multiple nodules < 1cm, 10 patients had thyroiditis findings. The last patient was diagnosed with Hashimoto thyroiditis with blood tests and imaging. Fine needle aspiration biopsy was performed for nodules > 1 cm or suspected for malignancy. Hurtle cells in one patient and papillary carcinoma in another was found. They were referred to surgery. The other biopsies were benign. These patients were followed and medication was started if needed according to guidelines. Conclusions: Thyroid diseases, especially hypothyroidism often accompanies obesity. Screening with a blood test for thyroid functions is convenient. But as it is possible to diagnose various thyroid pathologies in obese patients with normal thyroid hormone levels, thyroid ultrasonography should be added to screening methods. Thus, it would be possible to diagnose, follow and treat unknown thyroid pathologies and prevent probable serious consequences.

A-0017 Cigarette smoking and asymptomatic diastolic dysfunction in metabolically healthy obese patients Feray Akbas, Hanife Usta Atmaca, Fettah Sametoglu, Ilker Nihat Okten, Yasin Yuksel, Mustafa Boz Istanbul Training and Research Hospital, Internal Medicine Clinic, Istanbul,Turkey Purpose: Diastolic dysfunction is a disturbance in ventricular relaxation, distensibility or filling—regardless of whether the ejection fraction is preserved or depressed and whether the patient is asymptomatic or symptomatic. Here, we aimed to show the relationship between smoking and diastolic dysfunction in metabolically healthy obese patients. Material and methods: 100 obese patients without accompanying diseases or any signs of acute/chronic heart failure were included in the study. None of the patients were on any medications influencing diastolic dysfunction. None of them had metabolic syndrome according to IDF 2005 criteria. Age, gender, smoking habits, total cholesterol and HDL cholesterol levels, systolic blood pressure were screened. Two-dimensional doppler echocardiography was performed. Framingham Study Risk Assessment Tool for Estimating 10-year Risk of Having a Heart Attack was used to predict the future cardiovascular outcome. Data was statistically analyzed using SPSS Windows 11.5. Results: 33 smoking, 67 non-smoking, totally 100 obese patients were included in the study. 9 (27.3%) patients in smoking group and 20 (29.8%) patients in non-smoking group had diastolic dysfunction. 24 (72.7%) in smoking group and 47 (70.2%) patients in non-smoking group had normal echocardiography. There was no statistically significant difference for diastolic dysfunction between smoking and non-smoking groups. But for 10year Risk of Having a Heart Attack, non-smoking group had significantly lower risk compared to the smoking group. Also, the group with diastolic dysfunction had significantly higher risk when compared to group with no diastolic dysfunction. Conclusions: Recent studies have shown that asymptomatic diastolic dysfunction is a predictor of future cardiovascular morbidity and mortality. Obesity is a chronic inflammatory state which is related to diseases like diabetes, hypertension, metabolic syndrome which also increase the risk for cardiovascular diseases. Smoking is a well-known atherosclerotic risk factor. Although diastolic dysfunction does not especially seem to be increased in obese patients in our study, both smoking and diastolic dysfunction are related to increased cardiovascular risk.

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2015; (14) Supplementum 2; S1-S92 Thus, it is essential to encourage obese patients for smoking cessation and screen for diastolic dysfunction to take necessary precautions to prevent from potentiation of the cardiovascular risk. A-0018 Biliopancreatic diversion by Scopinaro for the treatment of patients with morbid obesity - a step back or step forward Andriy Lavryk, Mykola Manoilo, Olexander Tyvonchuk, Olena Dmitrenko Shalimovs National Institute of Surgery and Transplantology NAMS of Ukraine, Kyiv, Ukraine Introduction: Morbid obesity - one of the leading factors of premature death due to pathology associated with it. At the same time, bariatric surgery at present is the real way to treat obesity - with weight loss, reduction of comorbidity and mortality. Malabsorptive bariatric procedures can achieve perfect results, but with some compromises. According to the classical method proposed Scopinaro biliopancreatic diversion (BPD) consists of distal subtotal resection of the stomach, a division of the small bowel 250 cm from ileocecal valve, an anastomosis of distal small bowel to the stomach, and creating a common limb (CL) length 50cm. BPD provides weight loss due to a combination of restriction (reducing gastric volume 30-40%) and limiting the possibility of absorption of nutrients. Materials and methods: 76 patients underwent BPD from 2007 to 2013. We have modified classic technique - performed resection only antrum and increased CL to75-85 cm. The mean age of patients was 42 years. The mean body mass index (BMI) in patients was 47 kg / m² (38-63). Comorbidities: type II diabetes was diagnosed 19 (25%) patients, arterial hypertension - 16 (21%), hyperlipidemia in 17 (22.4%) patients preoperatively. The examination of patients (percentage of weight loss, nutritional status, level of comorbidity and metabolic disorders) conducted by 1,3,6 months to 2 years. Results: Decrease in body weight was observed in the first year faster, and after 24 months BMI was on average 32 kg/m² (28-36). 2 cases of protein deficiency (2.6%) in non-compliance patients, both patients were treated with parenteral nutrition. Repeated surgery for lengthening the CL no patient needed. Iron deficiency anemia was detected in 18 (23.6%) patients. Obesity-associated disease: in 17 of 19 patients (89%) with diabetes and in 11 of 16 (68%) with hypertension were cured, and the patients stopped taking drugs after surgery. Cholesterol and triglycerides were normalized at 100% of patients at 1 year after surgery.

The most frequent complications after surgery were gastrostasis - 18 cases (23%) and the development of peptic ulcers of the stomach - 9 (11.8%), which is good undergone conservative treatment, deaths were not. Conclusions: BPD - the most effective combined bariatric procedure with long-lasting results in terms of weight loss and improvement of obesity-related diseases, including diabetes of the second type. In terms of postoperative complications (gastrostasis, peptic ulcer) and mortality comparable with other bariatric procedures. However, it can cause serious nutritional and metabolic disorders in the remote period without adequate maintenance and substitution therapy. Our results show that increasing the length of the CL to 75-85 cm successfully offset the metabolic complications without reducing the overall effect of the surgery. And the intake of vitamins, minerals, iron and protein is necessary to provide for life to maintain normal metabolic and nutritional status. A-0020 The choice of anesthetic technique for general anesthesia in morbidly obese patients Andrij Lavryc, Olga Vynnichenko, Andrij Mazur National Institute of surgery and transplantation after O. O. Shalimov, Kiev Bariartric surgery is the most effective treatment for patients with morbid obesity. The choice of anesthetic technique for general anesthesia in morbidly obese patients remains controversial. Early and uneventful postoperative recovery of morbidly superobese patients remains a challenge for anesthesiologists. This study includes 82 patients with a mean body mass index 51,4 kg / m2 and we analyzed using sevofluran and propofol. The aim of the study was to investigate the difference between using sevofluran and propofol in morbid obese patients. Materials and Methods: 82 morbidly obese (IBW=51,4±8,3kg/m2) undergoing biliopancre¬atic diversion with duodenal switch procedures and sleeve gastractomy were studied. In the first group (52 patients), patients were anesthetized with sevoflurane, and sevoflurane being administered according to standard clinical practice. In the second group (30 patients) anesthesia was maintained with propofol. In both groups rocuronium (2,5 ± 0,3 mg / kg / min and 3,6±0,2 mg / kg/ min) and fentanil (0,1 mcg / kg / min±0,03 and 0,04 mcg / kg / min±0,01) had been used. Recovery times were recorded. Time to extubation was also noted. Results: Awakening and extubation times were

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OBESITOLOGIA HUNGARICA significantly shorter in sevoflurane group (P < 0.05). This study shows that the use of inhalation anesthesia reduces the doses of narcotic analgesics and muscle relaxants in patients with morbid obesity and reduce time to extubation.

subgroup (7.20 ± 3,02 and 9.85 ± 4,16, respectively). The difference between NO level in EBW female and EBW male was statistically significant. There were no significant changes in NO level among different age subcategories in both groups. NO level was negatively correlated with BMI and serum total cholesterol level.

A-0021 Relationship between nitric oxide and obesity in children Aleksandra Czumaj1, Marta Śledzińska2, Michał Brzeziński2, Barbara Kamińska2, Tomasz Śledziński1 1 Department of Pharmaceutical Biochemistry, Medical University of Gdańsk, Gdańsk, Poland 2 Department of Pediatric Gastroenterology, Hepatology and Nutrition, Medical University of Gdańsk, Gdańsk, Poland

Conclusions: We show here that obesity is associated with decreased level of NO. These results suggest that decreased level of NO could be involved in the development of cardiovascular disorders during growing up of children with excessive body weight.

Purpose: The nitric oxide (NO) is an important mediator involved in vascular homeostasis. Changes in NO level are considered to be associated with juveniles obesity and its clinical consequences like cardiovascular disease, diabetes, and hypertension. However, previous studies on NO levels in obese children provide inconclusive results. In the present study, the NO levels were compared in excessive body weight (EBW) and healthy children in order to assess whether childhood EBW is associated with changes in NO level. It was also investigated whether features like age and gender are associated with NO levels in selected groups. Materials: 37 normal weight and 43 EBW children, ageand gender-machted were included into the study. The subjects were qualified to EBW group if BMI percentile were ≥ 85, based on International Obesity Task Force. From all patients blood samples were collected. Outcome Measures: The NO level was evaluated on the basis of its stable products nitrate and nitrite. Moreover, various clinical parameters and body measurements in each group were determined. Methods: For the purpose of this study, we have assessed nitrite plus nitrate concentration in blood samples by colorimetric detection of the Griess reaction product. Moreover, selected biochemical parameters were measured. The significance of the results was tested by unpaired two-tailed t-test and linear regression analysis. Results: The NO level in EBW group was equal to 8.72 ± 3.09 [μM], whereas in normal weight group level NO was 22,22 ± 11,52 [μM]. The observed difference was statistically significant. The EBW female subgroup was characterized by lower level of NO than EBW male

A-0022 Past and future trends in the prevalence of overweight and obesity in Lithuania Vilma Kriaucioniene1, Janina Petkeviciene1, Laura Webber2 1 Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania; 1 UK Health Forum, London, UK Purpose: The study purpose was to assess changes of overweight and obesity prevalence between 2000 and 2012 in Lithuanian adult population and to project trends to 2050. Materials or Subjects: The data were obtained from six biennial cross-sectional nationally representative postal surveys from 2000 to 2012. In total, 5602 men and 7712 women aged 20-64 participated in these surveys. Outcome Measures: Self-reported body weight and height were used to calculate body mass index. Overweight was defined as BMI≥25 kg/m2 and obesity as BMI≥30 kg/m2. Methods: Lithuania participates in the EConDA project which is funded by the EU Commission and aims to develop models to test the differential effect of chronic disease interventions in population sub-groups. To project trends in obesity forward to 2050 by educational level a two-part modelling process was developed. The first part applies a multivariate, categorical regression analysis to cross-sectional BMI data by sex, age and education using data of 2000-2012 study years. The second part of the modelling process applies a microsimulation programme to enable longitudinal projections. Results: During the study period the most remarkable increase in the prevalence of obesity was found among 55-64 years men (from 14.9% in 2000 to 32.3% in 2012) and in the same age group of women (from 32.9% to 41.7%). By 2050, the prevalence of obesity among men was projected to increase across all age (except 20-29

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2015; (14) Supplementum 2; S1-S92 year old) and educational groups. In 2000-2012 the prevalence of overweight was higher among men with university education compared to less educated. However, projections suggest opposite trends, with the highest prevalence of overweight among less educated men over the next decades if trends go unchecked. In 2000-2012 the lower proportion of high educated women was overweight or obese compared to low educated. By 2050 inequalities in the prevalence of obesity and overweight among Lithuanian women was projected to increase: less educated women will have the prevalence of obesity 3.4 times higher and the prevalence of overweight - two times higher than those with university education. Conclusions: Projection of obesity trends showed educational and age differences in prevalence of obesity and overweight in Lithuania which are important for the planning of future health programs and policies. A-0023 Role of fractalkine/Cx3CR1 signaling in macrophage trafficing into adipose tissues and in the development of obesity Ágnes Polyák1,2, Zsuzsanna Winkler1,3, Szilamér Ferenczi1, Dóra Kővári1, Dániel Kuti1, Krisztina J. Kovács1 1 Laboratory of Molecular Neuroendocrinology, Institute of Experimental Medicine, Budapest, Hungary; 2 Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, Hungary; 3 János Szentágothai Neuroscience School, Semmelweis University, Budapest, Hungary Purpose: The purpose of the study was to investigate the role of fractalkine/Cx3CR1 signaling in macrophage trafficing and the development of obesity. Materials or Subjects: Experiments were performed on male Cx3CR1 +/gfp, and Cx3CR1 gfp/gfp mice on a C57BL6 background. Outcome Measures: Body weight, food intake, glucose tolerance, white and brown adipose tissue histology, inflammatory cytokine mRNA expression. Methods: Mice were fed with fat enriched diet (FatED, 2:1 mixture of standard chow and lard) or normal diet (ND) for 10 weeks starting at PND 35. Body weight and food consumption was measured weekly. Oral glucose tolerance test was performed two days before the end of the experiment. H&E staining was accomplished on paraffin embedded tissues. Gene expression analysis was performed by RT-PCR.

Results: FatED fed Cx3CR1 +/gfp mice became obese, developed glucose intolerance. Adipose cells in white adipose tissue, and lipid droplets in brown adipose cells were enlarged, macrophages infiltrated into white (WAT) and brown adipose (BAT) tissue. Inflammatory cytokine expression was elevated in both WAT and BAT. Compared to FatED fed Cx3CR1 +/gfp mice, FatED fed Cx3CR1 gfp/gfp mice resulted in lower body weight, and prevented the development of glucose intolerance. There were no difference in energy intake between the two groups. Adipose cells in WAT and lipid droplets in BAT were smaller, fewer macrophages were present in the tissues, and inflammatory cytokine expression was lower. Conclusions: Fractalkine/Cx3CR1 signaling has significant role in macrophage trafficing, and participates in the development of obesity and the infammation of WAT and BAT. A-0024 A study on the plantar pressure distribution among obese and non-obese participants Eleonóra Leidecker1, Mónika Galambosné Tiszberger2, Aliz Bohner-Beke3, Bálint Molics1, Melinda Járomi1, János Kránicz1 1 Pécs University Faculty of Health Sciences Institute of Physiotherapy and Sport Sciences, Pécs, Hungary 2 Pécs University Faculty of Business and Economics Department of Business Methodologies, Pécs, Hungary 3 Pécs University Faculty of Health Sciences School of Health Sciences, Pécs, Hungary Purpose: Almost all the literature emphasize the major role of body weight on foot health and foot loading, however its impact on regional plantar pressure is not well known. The aim of the study was to assess the impact of obesity on plantar pressure patterns among the working-age population. Materials: The study involved 180 healthy subjects (38.83+- 10.5 yrs, BMI range was 24.18+- 4.95 kg/m²). The plantar pressure patterns of two different BMI categories (non-obese and obese) were measured. Methods: The following three parameters on eight regions of the foot were studied by dynamic pedobarography: contact area, maximum force, and peak pressure. Results: Our results suggest that, compared with nonobese subjects, the peak pressure was the highest on the midfoot (p=0.000) and the forefoot (p=0.000). Regarding the maximum force, the most significant statistical

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OBESITOLOGIA HUNGARICA difference was also on the midfoot (p=0.000), with a value higher among the obese group. The contact area value on the total foot and the midfoot was lower among the non-obese subjects (p=0.001). Conclusions: Our results indicate that the impact of obesity on plantar pattern is of major significance. Foot loading, with the exception of the toes, increases significantly on the total foot, especially on the medial midfoot. We believe that the outcomes of our study will provide useful data for prevention and footwear design. A-0025 Only BMI is not enough for evaluation of nutritional state of professional soldiers in the Armed Forces of the Czech Republic Jana Fajfrová, Vladimír Pavlík, Miluše Vacková, Ondřej Blažek Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Science University of Defence Hradec Králové, Hradec Králové, Czech Republic Introduction: In the Armed Forces of the Czech Republic there has been introduced a system evaluating the health capability of active-duty service, regulation No 103/2005 Sb. One of the evaluation criteria is also the nutritional state assessed only by BMI values. Aim of our study was to determine real nutritional state of soldiers. Methods: Nutritional state assessment was focus on body composition measured by bioimpedance analysis supplemented with waist circumference, skinfold thickness, mid-arm circumference and hand grip strength test. Results: For now we enrolled 421 male soldiers and 81 female soldiers with mean age 31.6 ± 7.6 years and 29.2 ± 9.3 years, respectively. BMI was 26.0 ± 3.1 kg.m-2 vs. 23.8 ± 4.4 kg.m-2. Overweight was found in 50.4 % vs. 21 %, obesity in 9.7 % vs. 8.6 %. Percentage of body fat in range of overweight was found in 10.9 % vs. 33.3 % and in range of obesity was found in 5.9 % vs. 22.2 %. Waist circumference ≥ 94 cm for men and ≥ 80 cm for women was found in 9.7 % and 4.9 % and waist circumference ≥ 102 cm for men and ≥ 88 cm for women was found in 5.5 % and 7.4 %. Conclusion: First results of our work indicate that the BMI criterion as single parameter is inappropriate, especially for evaluating overweight and it is necessary to extend the current assessment algorithm with other parameters, which means waist circumference and percentage of total body fat. These parameters are able to complete the BMI values and better distinguish

individuals with the risk of development of obesity and associated complications fromphysically fit individuals with increased body weight due to well-developed musculature. Nowadays we prepare amendment of regulation about evaluating the health capability of active-duty service.

Supported by a long-term organization development plan 1011 A-0026 Nutritional state and physical fitness among civilian and military medical students Jana Fajfrová, Vladimír Pavlík, Ondřej Blažek, Miluše Vacková Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Science University of Defence Hradec Králové, Hradec Králové, Czech Republic Introduction: Becoming a student of university leads to significant change of lifestyle, especially eating habits a physical activity. Students of Military medicine are supposed to be in good shape in contrast to regular students of medicine. Aim of the study is to find out impact of university education on change of lifestyle, nutritional state, metabolic rate and physical fitness among medical students and comparison between military and civilian students. Methods: We enrolled students of first classes of Charles University Faculty of Medicine in Hradec Kralove and Faculty of Military Health Sciences University of Defence Hradec Kralove divided into two groups, military and civilian, with 30 students in each group. Design of study consists of first baseline measurement of nutritional state and control measurements perform each year during the university education. Body composition has been evaluated using eight-point tactile electrode method by multifrequency impedance analyser InBody 720. Resting energy expenditure (REE) was measured by indirect calorimetry (Vmax Encore). Physical fitness has been tested using cycle ergometry and handgrip strength test by digital tensometer. Results: Selected results of military group vs. civilian group: BMI 3.1 ± 2.0 kg/m2 vs. 21.9 ± 2.6 kg/m2 (p=0.97); percentage of body fat 16.5 ± 6.9 % vs. 16.6. ± 7.7 % (p= 0.47); waist circumference 76.0 ± 6.2 cm and 73.6 ± 7.4 cm (p= 0.91); percentage of body fat in normal range was in 70 % vs. 56.7 % (p=0.14); REE 88.3 ± 6.7 % vs. 88.2 ± 6.6 % (p= 0.52); mean heart rate on cycloergometry 138 ± 5 bpm and 141 ± 6 bpm (p=0,029), W170 2.5 ± 0.5 W/ kg vs. 2.1 ± 0.6 W/kg (p=0,99).

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2015; (14) Supplementum 2; S1-S92 Conclusion: Results of first measurement show that there is no significant difference between military and civilian group and both group have favourable nutritional state. Military students are heavier with more muscle mass and performed better on ergometry but with no statistical significance. Mild but significant difference was in mean heart rate during ergometry in favour of military students. We expected accenting of difference between groups in time.

Supported by a long-term organization development plan 1011 A-0027 Nutritional habits, physical activity and nutritional state of Czech military medical students Vladimír Pavlík, Jana Fajfrová, Miluše Vacková, Ondřej Blažek Department of Military Internal Medicine and Military Hygiene, Faculty of Military Health Science University of Defence Hradec Králové, Hradec Králové, Czech Republic Introduction: Becoming a student of university leads to significant change of lifestyle, especially eating habits a physical activity. On the contrary, students of military medicine are supposed to be in good shape to fulfill their military duties. Aim of work was the monitoring of nutritional state and lifestyle of military medical students. Methods: To evaluation were included 108 (67 men, 41 women) students of Faculty of Military Health Science with the mean age 21.9 ± 2.1 years. Nutritional state of students was evaluated by BMI, waist circumference, skinfold thickness, mid-arm circumference and bioelectrical impedance analysis. Muscle strength was evaluated using the hand grip test. Lifestyle was evaluated by food frequency and physical activity questionnaire. Results: Men vs. women; BMI 24.1 ± 2.5 kg.m-2 vs. 21.8 ± 2.3 kg.m-2, percentage of body fat 11.8 % vs. 21.4 %. Prevalence of normal weight according to BMI was 70.1 % vs. 87.8%, of overweight was 26.9 % vs. 12.2 % and of obesity was only 3.0 % vs. 0 %. Percentage of body fat in normal range was in 44.8 % vs. 51.2 %, below normal range was in 53.7 % vs. 48.8 % and in range of overweight was in only 1.5 %. Aerobic physical activity at least 3 times a week had 19.4 % vs. 87.5 % and anaerobic physical activity at least 3 times a week had 88 % vs. 75.6 %. Cereals, fruit and vegetables, meat, and dairy products were consumed daily. Sweets and coffee were consumed practically daily and alcohol 2 times a week. Only 9 men and 4 women were smokers.

Conclusion: In our group of military students was lower prevalence of overweight and obesity in comparison with Czech population. According to all of the results is clear that military medical students are kept in very good nutritional state, mainly thanks to regular physical activity and also to balanced nutritional habits in spite of higher consumption of sweets.

Supported by a long-term organization development plan 1011 A-0028 National Institute of Surgery and Transplantatiology Andriy Lavryk, Olena Dmytrenko, Andriy Zgonnyk, Mykola Manoylo National Institute of Surgery and Transplantatiology, Kyiv, Ukraine Introdution. Obesity is not only a medical but also a social problem. In Europe 45% to 70% of the population are overweight. Diet and drug therapy can achieve the desired result in only a small number of patients. Using surgical methods to reduce body weight not only reduces the weight and also normalizes metabolic disorders. All modern operating techniques bariatric surgery are associated with intervention on the stomach, especially angle of His. However, morphological and functional condition of the esophageal-gastric junction in obese patients has been insufficiently studied. Objective: To study the endoscopic changes and function of esophageal-gastric junction in patients with morbid obesity. Materials and Methods: Clinically examined 78 patients with morbid obesity: men were 28 (35.9%), women - 50 (64.1%), aged 19 to 62 years, mean age 42,3 ± 14,7; Average BMI - 47,50 ± 4,36 kg/m2. All the patients had undergo upper endoscopy (UE), esophageal manometry and intraesophageal pH-monitoring Results: 4 (5.12%) patients had endoscopic signs of hiatal hernia (HH) at 36 -38 cm. In 18 (23.07%) patients in UE was „opened” cardia, in 3 (4.65%) patients of them cardia closed partially. In 4 (5.12%) patients diagnosed cardia polyps. It should be noted that 14 (17.95%) of patients diagnosed endoscopic positive form of GERD, of whom 10 (12.820%) patients mucosal changes in the lower third of the esophagus consistent with reflux esophagitis LA-A, in 4 (5.12%) patients with reflux esophagitis LA-B. According to intraesophageal pH monitoring in 31 (39.74%) patients diagnosed GERD, of whom 17

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OBESITOLOGIA HUNGARICA (21.79%) with non-erosive form. DeMeester score was within 38.15 - 87.51, with an average of - 56,69 ± 5,86. Increased DeMeester score was due as an increase in the number of pathological reflux, and as increase in their duration. Reflux in the afternoon it was characterized by an increase in their number and duration after meal. Basal pH in the esophageal lumen was within 3.20 - 6.30, the mean value of 4,43 ± 0,27. In 27 (34.31%) patients had lower esophageal sphincter pressure was reduced, the average value of 8,44 ± 0,97 mm Hg. In 6 (7.69%) patients with reduced LES pressure in the esophageal pH monitoring pathological gastroesophageal reflux are not registered. In 4 (5.12%) patients diagnosed HH type I, II degree. In no one of patients gastroesophageal reflux was registered by X-ray barium swallow. Conclusions: The status and function of the esophagealgastric junction in patients with morbid obesity deserves attention and further study, and it should be consider when choosing a type of bariatric operation. In addition, much important to study the state of esophagealgastric junction in patients after weight loss and weight normalization. A-0029 Τhe issue of bulimic behavior over time: it’s a disease or a phenomenon of the modern era. Bulimia through the lens of scientific research Athanasia Antiochou INVESTIGATION OF «ΤHE ISSUE OF ’’ΒULIMIC BEHAVIOR’’ OVER TIME: IT’S A DISEASE OR A PHENOMENON OF THE MODERN ERA; BULIMIA THROUGH THE ’’LENS’’ OF SCIENTIFIC RESEARCH» Dietitian-Nutritionist Aim: The aim of the study was the fact that bulimia is a delicate lasting value issue that needs careful treatment. If we consider that psychogenic eating disorders are complex disorders and the disordered eating habits often are accompanied by psychological difficulties which need to be cured will be obvious the importance of the issue. Specifically, we were tried to determine the reasons why a person is led to bulimic episodes and to identify the reasons why a bulimic person wants to tackle this problem. Material: 75 people (73 women and 2 men) were participated in this research. The sampling was almost by accident; with the help of a dietetic office which is specialized in treating bulimic incidents we were communicated with people who visited the clinic.

Method: An almost closed questions questionnaire was supplemented by the individuals. In addition there were also some open-ended questions to explore their reasons for existence problem or ways of facing the situation. After collected the questionnaires all questions were coded and analyzed using the statistical package SPSS (statistical package for the social sciences). Results: After analysis it was appeared that eating disorders are emotional and physical problem which are associated with obsessive thoughts about food weight and body image. They usually begin in adolescence. Teenage girls and young women are more at risk of anorexia nervosa and bulimia. Of the total of patients presenting bulimia or anorexia, only 10% to 15% are men. An estimated 1.1% to 4.2% of women have bulimia nervosa at some point in their lives. For anorexia nervosa this percentage ranges from 0.5% to 3.7%. Conclusions: The bulimic persons usually have normal or near normal body weight. If coexist and anorexia nervosa then weight loss in observed. People with bulimia nervosa, afraid to gain weight, desire to lose weight and feel very bad about their bodies. Also they feel really bad and ashamed of the incidents that have bulimia. Keep secret such behavior. After the cancellation behavior following the bulimic episode, they feel better. A-0030 Subsidy targeting program through cash transfer on food security and women’s overweight/obesity in urban population of Tehran Fatemeh Mohammadi-Nasrabadi1, Nasrin Omidvar1, Mohammad-Reza Khoshfetrat1, Anahita Houshiar-Rad1, Nahid Zerafati-Shoa1, Nasrin Hoseinpoor1, Homa Heidari1, Telma Zoghi1, Monireh Dadkhah1, Yadollah Mehrabi2 1 National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2 Biostatistic Department, Faculty of Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Purpose: Cash transfer is one of the strategies used by many developing countries to improve food security and nutritional status of lower socio-economic groups. The aim of the present study was to compare food security and women’s overweight/obesity of urban households before and after targeted subsidy cash transfer program in the city of Tehran. Subjects: The study population included households from six districts with different socio-economic status in

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2015; (14) Supplementum 2; S1-S92 the city of Tehran. Food security and food expenditures data on each household were collected in 2009 (before) and 2012 (after) implementation of the policy, through interviews at the subject’s home. Outcome measure: Data gathered in both period included: a)demographics; b)food security by previously validated Household Food Insecurity Access Scale (HFIAS); c)Dietary intake by three consecutive 24 hours recalls. In addition, weight, waist and height of women were measured and body mass index (BMI) was computed. Chi-squared test was used for analyzing differences in qualitative variables and differences in quantitative variables were analyzed using paired t-test and one way analysis of variance (ANOVA) before and after the targeted subsidy policy implementation. Results: Based on the results, the frequency of food secure households has declined from 56.4% to 43.5%, mild food insecurity has increased from 19.3% to 28.4%, moderate food insecurity has risen from 13.3% to 15.5% and severe food insecurity has grown from 11% to 12.5% in the second measurement. Consumption survey showed significant decrease in consumption of meat and dairy groups after changing commodity subsidy program to cash transfer in household’s residents in Tehran. Weight (from 70.6±0.8 to 71.4±0.9), waist (from 87.4±0.7 to 89.9±0.8) and BMI (from 28.7±0.3 to 29.0±0.3) increased significantly after 3 years in women (p