Development of Small Diameter Nanofiber Tissue ... - Semantic Scholar

4 downloads 0 Views 10MB Size Report
Apr 1, 2015 - Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, et al. Inter-Society ... Naito Y, Shinoka T, Duncan D, Hibino N, Solomon D, Cleary M, et al. Vascular .... Athanasiou KA, Niederauer GG, Agrawal CM.
RESEARCH ARTICLE

Development of Small Diameter Nanofiber Tissue Engineered Arterial Grafts Hirotsugu Kurobe1☯, Mark W. Maxfield2☯, Shuhei Tara1, Kevin A. Rocco2, Paul S. Bagi2, Tai Yi1, Brooks Udelsman2, Zhen W. Zhuang2, Muriel Cleary2, Yasuko Iwakiri2, Christopher K. Breuer1, Toshiharu Shinoka1* 1 Nationwide Children’s Hospital, Columbus, Ohio, United States of America, 2 Yale University School of Medicine, New Haven, Connecticut, United States of America ☯ These authors contributed equally to this work. * [email protected]

Abstract OPEN ACCESS Citation: Kurobe H, Maxfield MW, Tara S, Rocco KA, Bagi PS, Yi T, et al. (2015) Development of Small Diameter Nanofiber Tissue Engineered Arterial Grafts. PLoS ONE 10(4): e0120328. doi:10.1371/ journal.pone.0120328 Academic Editor: Donghui Zhu, North Carolina A&T State University, UNITED STATES Received: July 26, 2014 Accepted: January 20, 2015 Published: April 1, 2015 Copyright: © 2015 Kurobe et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper and its Supporting Information files. Funding: YI received grant support from National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases (R01DK082600). Funding for this study was provided by the OHSE Committee (Department of Surgery, Yale University School of Medicine). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have the following interests: CB and TS have received grant

The surgical repair of heart and vascular disease often requires implanting synthetic grafts. While synthetic grafts have been successfully used for medium-to-large sized arteries, applications for small diameter arteries (