Diagnostic performance of 64-slice computed tomography coronary ...

0964-08_ActaCardio_63-1_03_07-3101

Acta Cardiol 2008; 63(1): 11-17

ORIGINAL

29-01-2008

13:50

Pagina 11

doi: 10.2143/AC.63.1.2025326

11

ARTICLE

Diagnostic performance of 64-slice computed tomography coronary angiography to detect significant coronary artery stenosis

Fatih BAYRAK1, Tahsin GUNEYSU2, Gokmen GEMICI1, Deniz SEVINC2, Bulent MUTLU3, Semih AYTACLAR2, Muzaffer DEGERTEKIN1 1 Yeditepe

University Hospital, Cardiology Department; 2 Sonomed, Radiology Department; 3 Kosuyolu Heart and Research Hospital, Istanbul, Turkey. Objective — We aimed to determine the diagnostic accuracy of 64-slice multi-slice computed tomography (MSCT) to detect significant coronary artery stenosis with comparison to conventional coronary angiography (CCA). Methods — In 100∞∞patients (70∞∞men, average age 58∞∞±∞∞10∞∞years and age range 31-75∞∞years) scheduled to have conventional coronary angiography, MSCT was performed before catheterization (within 2∞∞months).All patients were in sinus rhythm, able to hold breath for 15∞∞seconds, and had serum creatinine levels∞∞∞ 1.5∞∞mg/dl), inability to follow breath-hold commands, previous coronary artery bypass surgery and intervening cardiac event between MSCT and CCA (a total of 22∞∞patients was excluded). For the remaining 100∞∞patients, indications for CCA were atypical chest pain in 30, stable angina pectoris in 52, and unstable angina pectoris and non-ST elevation myocardial infarction in 18. All patients gave written informed consent to undergo MSCT, the study was approved by the local ethics committee and the procedures followed were in accordance with the Declaration of Helsinki.

PATIENT

PREPARATION

One hour before MSCT imaging, patients with heart rates over 65∞∞beats/min received 100∞∞mg atenolol, patients with heart rates between 50-65∞∞beats/min received 50∞∞mg atenolol. Continuous monitoring for heart rate and blood pressure was performed and if necessary additional intravenous metoprolol (5-20∞∞mg) was administered to achieve a target heart rate∞∞