In absence of NRG-1, Ang II induced arterial hypertension, concentric LV hy- pertrophy, interstitial myocardial fibrosis, and LV diastolic failure (increased slope.
Pathophysiology
dent predictor of the nondipping pattern in our cohort (p=0.008, OR: 1.12, 95% confidence interval: 1.03-1.22). Table 1
Age (years) Male sex (n) Left atrial volume index (mL/m2 ) LV mass index (g/m2 ) Mitral E wave (m/s) E/A ratio Lateral e’ (cm/s) E/e’ ratio Vp (cm/s) Pulmonary vein S wave (m/s)