Economic Modeling of Type 2 Diabetes Mellitus

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Diabetes is a chronic condition that affects millions of people worldwide. According to the ... The United Arab Emirates is ranked 10th in the world in terms of ...
   

Economic  Modeling  of  Type  2   Diabetes  Mellitus    

Zohour  Anouassi A00017460   Paris  Sorbonne  University  Abu  Dhabi  

I n i t i a t i o n   t o   R e s e a r c h   i n   E c o n o m i c s   P r o f e s s o r   G r é g o i r e   R o t a   G r a z i o s i  

Economic  Modelling  of  Type  2  Diabetes  Mellitus    

Zohour  Anouassi    

Table  of  Contents   INTRODUCTION  ___________________________________________________________________   3   ACADEMIC  LITERATURE   ____________________________________________________________   3   TRADE-­‐OFF  _______________________________________________________________________   4   SIGNIFICANCE  OF  THE  STUDY  ________________________________________________________   4   EXPECTED  OUTCOME/RESULT   _______________________________________________________   4   CONCLUSION  _____________________________________________________________________   4   BIBLIOGRAPHY   ___________________________________________________________________   5  

 

Job  Oriented  Course  –  Dr.  Grégoire  Rota  Graziosi  

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Economic  Modelling  of  Type  2  Diabetes  Mellitus    

Zohour  Anouassi    

Introduction   Diabetes   is   a   chronic   condition   that   affects   millions   of   people   worldwide.   According   to   the   World   Health   Organization   (WHO),   approximately   180   million   people   suffer   from   Type   2   diabetes   (Thurecht,  Brown,  &  Yap,  2011).  The  organization  also  estimates  that  the  prevalence  of  the  condition   is   going   to   increase   by   at   least   15%   by   the   year   2030   (Willis,   Asseburg,   &   He,   16).   The   increase   in   prevalence   implies   that   more   people   will   be   suffering   from   the   condition,   thus   creating   an   urgent   need  to  address  such  a  problem  in  the  present.  The  United  Arab  Emirates  is  ranked  10th  in  the  world   in  terms  of  prevalence  of  Type  2  Diabetes.  Currently,  approximately  20%  of  the  population  suffers   from   the   condition.   Diabetes   has   been   linked   to   several   complications   that   increase   the   economic   burden   of   handling   the   condition   for   both   individuals   and   the   health   sector.   For   example,   Type   2   Diabetes  leads  to  complications  of  the  liver,  the  kidney,  and  the  heart  (Govan,  Wu,  Lindsay,  &  Briggs,   2015).   The   burden   of   managing   the   condition   together   with   its   associated   risks   increases   as   the   prevalence   rises.   Governments   experience   difficulty   in   addressing   such   a   problem   through   recent   strategies   implemented   because   there   is   no   way   of   telling   whether   the   desired   results   will   be   achieved.   Economic   models   help   to   address   this   problem   by   providing   a   reliable   forecast   of   how   interventions   implemented   in   the   present   will   impact   the   future   state   of   diabetes   within   a   given   population.  Economic  modelling  of  Type  2  Diabetes  has  been  used  in  the  past  to  help  governments   justify  healthcare  spending  meant  to  reduce  the  prevalence  of  the  disease  and  help  those  who  are   already   victims   to   better   manage   their   condition   so   as   to   reduce   risks   of   further   complications.   Additionally,   economic   modelling   helps   to   discern   which   interventions   will   be   cost-­‐effective   and   yield  more  positive  results  in  the  future.  The  proposal  seeks  to  examine  economic  models  of  Type  2   Diabetes  that  have  been  designed  in  the  past  and  establish  their  significance  in  tackling  the  problem   in  the  United  Arab  Emirates.  The  study  hypothesizes  that  there  is  a  proposed  model  in  the  current   literature  that  can  match  the  needs  of  Unites  Arab  Emirates  health  initiative  and  be  used  to  justify   programs  meant  to  address  the  problem  in  the  present.   Academic  Literature   The   study   will   be   conducted   through   a   systemic   review   process.   Prominent   databases   that   are   home   to   medical   journals   tackling   diabetes   issues   will   be   selected.   Such   databases   include   PubMed,  EBSCOhost,  and  Medline.  The  databases  will  be  searched  for  articles  addressing  economic   modelling  of  Type  2  Diabetes.  To  increase  the  volume  of  relevant  articles  for  a  sufficient  analysis,  the   search   will   include   all   articles   written   in   the   last   decade.   An   exclusion   criterion   will   be   used   to   determine  the  articles  that  will  qualify  for  the  final  analysis.  Firstly,  articles  that  conduct  a  systematic   review   will   be   excluded.   Such   articles   will   mostly   have   summaries   of   information   on   all   the   available   models,  thus  compromising  the  level  of  analysis  that  can  be  performed  on  them.  Secondly,  articles   that  focus  on  clinical  trials  conducted  to  test  the  viability  of  a  given  model  will  be  excluded.  Clinical   trials   usually   occur   in   the   highly   controlled   environment,   which   limits   the   applicability   of   their   findings   to   other   environments.   However,   in   the   case   of   economic   models   that   have   had   clinical   trials   conducted   in   different   environments,   the   study   will   consider   them   because   their   degree   of   generalizability  will  have  improved.   A  research  will  also  be  conducted  by  the  Ministry  of  Health  in  the  United  Arab  Emirates  to   determine   factors   that   the   ministry   considers   important   in   tackling   the   Type   2   Diabetes.   The   research   will   also   seek   to   evaluate   the   resources   available   at   the   ministry's   disposal   to   determine   which  models  best  fit  with  the  ministry's  goal  of  preventing  cases  of  Type  2  Diabetes  and  managing   the   condition   of   current   victims   to   reduce   risks   of   complication.   After   evaluating   the   ministry's   goals   and   resources,   they   will   be   matched   to   the   proposed   economic   models   contained   in   the   current   literature.  The  models  will  be  chosen  on  the  basis  of  applicability  in  the  current  United  Arab  Emirates   health   sector   and   their   ability   to   deliver   positive   results   in   the   most   cost-­‐effective   manner.   The   identified  model  will  then  be  recommended  to  the  ministry  to  help  fight  the  diabetes  menace.  The   Job  Oriented  Course  –  Dr.  Grégoire  Rota  Graziosi  

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Economic  Modelling  of  Type  2  Diabetes  Mellitus    

Zohour  Anouassi    

model   will   be   used   to   justify   spending   on   Type   2   Diabetes   programs   and   provide   enough   guarantees   that  interventions  made  in  the  present  will  reduce  the  prevalence  of  the  disease  in  the  future.   Trade-­‐off   Economic   modelling   has   significant   benefits   compared   to   short-­‐term   prevention   and   treatment   methods   used   in   Type   2   Diabetes.   As   argued   by   Watson,   Preston,   Squires,   Chilcott,   and   Brennan  (2014),  the  high  prevalence  of  the  condition  in  the  population  requires  a  long-­‐term  strategy   that   fuses   both   prevention   and   treatment   methods   to   reduce   the   prevalence   of   the   condition   in   the   future.   However,   such   strategies   take   long   before   their   fruits   can   be   realized.   Governments   and   health   ministries   are   discouraged   from   embracing   such   strategies   because   they   have   no   way   of   ascertaining  their  success  in  the  future.  Economic  modelling  provides  a  solution  to  the  problem  by   allowing   stakeholders   to   determine   the   important   factors   they   want   to   address   in   the   future   and   how   such   factors   match   the   resources   at   their   disposal.   It   then   becomes   easy   to   justify   the   implementation   of   a   long-­‐term   project   that   has   more   chances   of   reducing   the   prevalence   of   the   condition  in  the  future.   Significance  of  the  Study   Currently,  the  health  sector  in  the  United  Arab  Emirates  uses  traditional  prevention  and  cure   methods   to   address   the   problem   of   diabetes.   However,   such   methods   have   not   proved   very   effective  in  the  past  because  the  prevalence  of  diabetes  has  continued  to  rise  through  the  years.  The   study   is   significant   in   the   sense   that   it   will   allow   the   Ministry   of   Health   to   implement   long-­‐term   interventions   that   have   a   high   probability   of   reducing   the   population   affected   by   Type   2   Diabetes.   The   study   will   help   the   ministry   identify   an   economic   model   of   Type   2   Diabetes   that   matches   its   resources   and   objectives.   The   model   will   then   be   used   to   justify   healthcare   spending   directed   towards   long-­‐term   projects   meant   to   reduce   the   prevalence   of   the   condition.   Secondly,   the   study   will   contribute   to   the   literature   on   the   subject   especially   on   environmental   factors   that   determine   which  economic  model  is  applicable  in  a  given  setting.   Expected  Outcome/Result   The   study   hopes   to   identify   an   economic   model   of   Type   2   Diabetes   that   can   be   used   to   reduce   the   prevalence   of   the   disease   in   the   United   Arab   Emirates   population.   It   will   also   identify   the   specific  environmental  factors  that  make  such  a  model  suitable  for  the  UAE's  case.   Conclusion   Diabetes  is  a  global  problem  that  affects  millions  of  people  daily.  Due  to  the  complications   associated   with   Type   2   Diabetes,   individuals   and   governments   face   significant   economic   and   healthcare  burden  as  they  try  to  address  the  condition.  The  prevalence  of  diabetes  worldwide  has   been   on   an   increase   through   the   years.   Long-­‐Term   strategies   are   thus   required   to   address   the   problem   fully   and   reduce   its   prevalence.   The   study   seeks   to   conduct   a   systematic   review   on   economic  models  of  Type  2  Diabetes  that  can  be  implemented  in  the  UAE  to  reduce  the  prevalence   of  the  disease  and  its  economic  burden.  

Job  Oriented  Course  –  Dr.  Grégoire  Rota  Graziosi  

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Economic  Modelling  of  Type  2  Diabetes  Mellitus    

Zohour  Anouassi    

Bibliography   Govan,  L.,  Wu,  O.,  Lindsay,  R.,  &  Briggs,  A.  (2015).  How  do  diabetes  models  measure  up?  A  review  of   diabetes  economic  models  and  ADA  guidelines.  Journal  of  Health  Economics  and  Outcomes  Research   ,  3  (2),  132-­‐152.   Thurecht,  L.,  Brown,  L.,  &  Yap,  M.  (2011).  Economic  modeling  of  the  prevention  of  Type  2  Diabetes  in   Australia.  International  Journal  of  Microsimulation  ,  4  (3),  71-­‐80.   Watson,  P.,  Preston,  L.,  Squires,  H.,  Chilcott,  J.,  &  Brennan,  A.  (2014).  Modelling  the  Economics  of   Type  2  Diabetes  Mellitus  Prevention:  A  Literature  Review  of  Methods  ,  12  (3),  239-­‐253.   Willis,  M.,  Asseburg,  C.,  &  He,  J.  (16,  8  1007-­‐1021).  Validation  of  economic  and  health  outcomes   simulation  model  of  type  2  diabetes  mellitus  (ECHO-­‐T2DM).  Journal  of  Medical  Economics  .    

Job  Oriented  Course  –  Dr.  Grégoire  Rota  Graziosi  

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