Effectiveness of a 12-month Exercise Program on Physical ...

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Abstract. Aim: The study aimed at determining whether physical exercise training improves the quality of life (QoL) and physical fitness of breast cancer survivors ...
ANTICANCER RESEARCH 32: 3875-3884 (2012)

Effectiveness of a 12-month Exercise Program on Physical Performance and Quality of Life of Breast Cancer Survivors TIINA SAARTO1, HEIDI MARIKA PENTTINEN1, HARRI SIEVÄNEN2, PIRKKO-LIISA KELLOKUMPU-LEHTINEN3, LIISA HAKAMIES-BLOMQVIST4, RIKU NIKANDER2,5, RIIKKA HUOVINEN6, RIITTA LUOTO2,7, HANNU KAUTIAINEN8, SALME JÄRVENPÄÄ9, IRJA IDMAN1, MERI UTRIAINEN1, LEENA VEHMANEN1, ANNA-STINA JÄÄSKELÄINEN1, ANNELI ELME1, JOHANNA RUOHOLA6, TIINA PALVA10, HARRI VERTIO11, MATTI RAUTALAHTI12, MIKAEL FOGELHOLM2,4, CARL BLOMQVIST1 and MINNA-LIISA LUOMA13,14 1Department

of Oncology, Helsinki University Central Hospital, Helsinki, Finland; UKK Institute for Health Promotion Research, Tampere, Finland; 3Department of Oncology, Tampere University Central Hospital, Tampere, Finland; 4Finnish Academy, Helsinki, Finland; 5Helsinki Metropolia University of Applied Sciences, Helsinki, Finland; 6Department of Oncology, Turku University Central Hospital, Turku, Finland; 7National Institute for Health and Welfare, Helsinki, Finland; 8Unit of Family Practice, Central Finland Central Hospital, Jyväskylä, Finland; 9The Medcare Foundation, Äänekoski, Finland; 10Pirkanmaa Cancer Society, Tampere, Finland; 11Cancer Society of Finland, Helsinki, Finland; 12Finnish Medical Society Duodecim, Helsinki, Finland; 13Department of Psychology, University of Helsinki, Helsinki, Finland; 14Unit of Functional Capacity, National Institute for Health and Welfare (THL), Helsinki, Finland 2The

Abstract. Aim: The study aimed at determining whether physical exercise training improves the quality of life (QoL) and physical fitness of breast cancer survivors. Patients and Methods: A total of 573 breast cancer survivors were randomized into an exercise or a control group, 12-months after adjuvant treatments. EORTC QLQ-C30 and BR-23 questionnaires were used for evaluation of QoL, FACIT-F for fatigue and the Finnish modified version of Beck’s 13-item depression scale (RBDI) for depression. Physical fitness was assessed by a 2-km walking test, and a figure-8 running test and physical activity (PA) by metabolic equivalent (MET) hours per week (MET-h/wk). Results: Figure-8 running time improved significantly among the patients of the intervention group compared with the controls (p