Jun 30, 2015 - Yu-Hsuan Lin; Kuo-Ping Chang; Yaoh-Shiang Lin; Ting-Shou ChangEmail author ... Previous studies report body-mass index (BMI) and percent weight loss (WL) to ... 3-year disease specific survival (p = 0.341), 3-year locoregional free ... The online version of this article (doi:10.1186/s13014-015-0443-3) ...
Lin et al. Radiation Oncology (2015) 10:136 DOI 10.1186/s13014-015-0443-3
RESEARCH
Open Access
Evaluation of effect of body mass index and weight loss on survival of patients with nasopharyngeal carcinoma treated with intensity-modulated radiation therapy Yu-Hsuan Lin1,2, Kuo-Ping Chang1, Yaoh-Shiang Lin1,2 and Ting-Shou Chang1,2,3*
Abstract Background: Previous studies report body-mass index (BMI) and percent weight loss (WL) to have prognostic significance when treating patients with nasopharyngeal carcinoma (NPC). However, most of these investigations studied patients treated using different radiotherapeutic techniques. We evaluated the predictive effect of these two nutrition-related measurements on therapeutic outcome in NPC patients who only received intensity-modulated radiation therapy (IMRT) as part of their total treatment program. Methods: We retrospectively studied NPC patients treated with IMRT from January 2006 to February 2012. Cox proportional hazards was used to test the association of pretreatment BMI (
