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Fresenius Environmental Bulletin. 4708. EFFECTS OF .... carried out using the SPSS 10.0 statistical program. (SPSS Inc. ..... Email: [email protected].
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Volume 25 – No. 11/2016, pages 4708-4713

Fresenius Environmental Bulletin

EFFECTS OF ROSEHIP EXTRACTS ON COMMON CARP (CYPRINUS CARPIO L.) TSH AND THYROID GLAND ACTIVITY Mehmet Ilker Dogru,1 Huseyin Polat,1 Kenan Erdogan,1 Arzu Dogru,2 Sevket Kandemir,3 Gulnihal Orun,4 Savas Yilmaz,5 Hasan Akgul,6 Ibrahim Orun 1* 1Department

of Biology, Aksaray University, Turkey of Science Teaching, Aksaray University, Turkey 3Department of Science Teaching, Amasya University, Turkey 4Vocational School, Aksaray University, Turkey 5Department of Biology, Ondokuz Mayis University, Turkey 6Department of Biology, Akdeniz University, Turkey

2Department

health conditions of fish as well as other vertebrates, and in defining the effects of various nutrition diets on growth and development in aquaculture. Although fish growth depends on the control of growth hormones, fish rely on thyroid and reproduction hormones for health growth. It is reported that Hypothalamic-pituitary thyroid axis (HPT) hormones play a vital role of reproduction metabolism due to their effects on energy metabolism, lipid metabolism, reproduction [2-5] and genetic transcription [6, 7]. In their study on Oryzias latipes fish species, Tagawa and Hirano state that partial depletion of T3 and T4 hormones greatly influences incubation, survival and developmental features of juvenile fish [8]. Other studies suggest that thyroid gland inhibition causes larval and juvenile fish not to go through metamorphosis [9] and exogenous T3 and T4 application cause early metamorphosis [10]. Recently, there are scientific researches seeking alternative natural solutions effecting animal health and growth in economically significant domesticated animals and aquaculture. These attempts rather depend on therapeutic and edible plants. The members of Rosaceae family have been used for food and medical needs throughout the world since early ages. They are used especially as medicine due to phenolic compounds, vitamins, anions, and cations they contain [11]. Rosehip, thanks to its polyphenol group compounds, is reported to be antioxidant, antidiabetic, anti-inflammatory, and effective in improving immunity system and lowering cholesterol [12-15]. These kinds of studies are mostly carried out on mammals as model animals. Studies on plant extracts with therapeutic effect on this and other kinds of fish are limited.

ABSTRACT The objective of this study was to evaluate the effects of rosehip extracts on serum thyroid stimulating hormone (TSH) and thyroid gland activity [free and total triiodothyronine (FT 3 and TT 3) and free and total thyroxine (FT 4 and TT 4)] of common carp which were acutely and subchronically exposed (4 and 30 days) to 5, 10 and 20 ppm of dosage. According to the experimental results, the decrease of serum TSH levels in 5 ppm group and the increase of serum TSH levels in 10 and 20 ppm groups were significant (p