1971-1972 n = 4,498. Stage III. 1977-1979 n = 4,190. Stage IV. 1981-1984 n = 3,204. Stage V. 1987-1991 n = 2,446. Reykjavik Study cohort. 18,912 participants.
Figure S1. Flow-chart of the Reykjavik Study. All males born between 1907 and 1934 and females born between 1908 and 1935 residing in Reykjavik or adjacent communities on December 1st 1966
Stage I 1967-1969 n = 4,574
Stage II 1971-1972 n = 4,498
Stage III 1977-1979 n = 4,190
Stage IV 1981-1984 n = 3,204
Stage V 1987-1991 n = 2,446
Reykjavik Study cohort 18,912 participants
Follow-up up to December 1999 (median, 19.4 years)
2,415 incident CHD cases, 3,897 matched controls
Exclusion of participants with cardiovascular disease at baseline or missing information on exposures or covariates