Figure S3 - PLOS

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Page 1. Control. IgG2a. CD11b. CD11c. Siglec H. cDC. (1.1%). pDC. (0.9%). cDC. (1.0%). pDC. (0.7%). SpiC. -/-. SpiC. +/-. Macrophages. Dendritic Cells. F4/80.
A

Macrophages

B

Dendritic Cells

Frequency

CD11b

Control

1.2%

RPM (0.0%)

IgG2a Mono (3.3%)

Siglec H

0%

cDC (1.1%)

pDC

RPM (2.0%)

F4/80

CD11c Mono (3.8%)

+

-

+

-

mPDCA-1

-

+

-

+

Siglec H

cDC (1.0%)

RPM (0.2%)

CD11c

* 1000

100

SpiC +/- -/-

D

10000

IFNB (pg/ml)

IFNB (pg/ml)

C

*

*

1000 100 10 1

SpiC +/- -/- +/- -/IgG2b + + - mPDCA-1 - - + +

E

100

IFNB (pg/ml)

F4/80

RPM

IgG2b

pDC (0.7%)

CD11b

SpiC-/-

Gran (2.3%)

0.4%

pDC (0.9%)

CD11b

SpiC+/-

Gran (1.1%)

0.8%

*

10

1

IgG2b + mPDCA-1 - +