Oct 16, 2011 - First announcement of the Fanconi anemia International Registry [letter] http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml# ...
From bloodjournal.hematologylibrary.org by guest on October 16, 2011. For personal use only.
1982 60: 1054
First announcement of the Fanconi anemia International Registry [letter] AD Auerbach and TM Schroeder
Information about reproducing this article in parts or in its entirety may be found online at: http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about ordering reprints may be found online at: http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#reprints Information about subscriptions and ASH membership may be found online at: http://bloodjournal.hematologylibrary.org/site/subscriptions/index.xhtml
Blood (print ISSN 0006-4971, online ISSN 1528-0020), is published weekly by the American Society of Hematology, 2021 L St, NW, Suite 900, Washington DC 20036. Copyright 2011 by The American Society of Hematology; all rights reserved.
From bloodjournal.hematologylibrary.org by guest on October 16, 2011. For personal use only.
CORRESPONDENCE
First To the
Announcement
Fanconi
Arleen
D.
West
Germany,
order
to establish
known
and
our
method
based
amniotic
fluid
(Auerbach gather
genetic,
define
the
hematologic,
and
heterogeneity
differential
diagnosis,
including
the incidence
and
study
study.
aware
of patients
aim
data
of donor
Clinic
reports.
blood
without
trouble
with
that
and
efficient
Doing
fewer
money
but
disease,
clinicians
and
hematology
physicians
to join
and scientists
test
other
at
tests
as pointed
most
out
Assistant The
York
New
Professor
E. Rosenfield, ofPathology
In
York
1982),
S.P.
review
To the
Masouredis
Med.
number Genetics
paper
of Heidelberg
Neuenheimer Heidelberg Germany
Dr.
Rosenfield’s
of transfused
recipients
cited
mediated
Feld
West
328
by Rosenfield, cell
Washington,
et al. (American remarking at risk and
for delayed
basis
of
Taswell
units
of
hemolysis.”
patient
transfused
blood
however, tion,”
Clinic
Taswell
(“A
America ,
cations fusion
pp 71-92)
seminar
with
Clinic,
the
incidence
increased
from
Blood
indicates
over
I in 400
transfused
more figures
and
me that
4 units Banks,
units
transfused Second,
cell
destruc-
Washington,
of identified
Medicine CUNY
Department and
of
Clinical
Sinai
Microscopy
Hospital
York, N. Y.
administered
reactions
manifested
(1964-1973) The
patients
at Mayo
and,
in fact,
have
estimate
delayed seminar of
and did
not quote
by serologic
changes.
To
attention
only
come
positive
to our
antibody
no evidence
Blood
an incidence
incidence,
screen
and
of hemolysis
The
on immune-
reported This
have
of the
hemolysis.
Association
of I : I 500 units only
of my
for
et al. (“A
pp 71-92)
per patient.
patients
developed
correction at risk
Banks, of post-
the number
however,
includes
quote,
direct
“Some
because
of a
Coombs
test
or shortened
blood
cell
hemolysis
in
survival.”
The
difficulty
transfused namely,
that
required
for
difficulty
with
my
concluding
compatibility and
effective
defining
the
risks
of
illustrates
the
thesis
developed
in
patients
assessing
the
compatibility Dr.
remarks
testing in
final
point, out for
my
that
I have
I reference
the current if we had
predicting
in
review,
procedures
problem.
since
be unnecessary
methods
in
laboratory
is a complex
by pointing would
vitro
appropriate
testing
Rosenfield’s
clinical
no
him
in
debate more
vivo
on
reliable red
cell
survival.
D.C., communi-
hemolytic
(1978-1980).
likely Howard
blood.
improved
be
on the
Dr.
each
of
continuingly
1:6200
to 1:1400
incorrect
the
immune-mediated
of
then
1054
on
that,
and
that
of
Association
(1974-1977)
Bank
American
1981,
hemolysis
of units
by
was both
et al. gave told
average
showed
at Mayo reactions
an
1980) may
not patients,
has personally
Moore
recipients
understated
and
ofS.B.
74:94-97,
(0.025%)
Moore
59:873-875,
report
interpretation
gravely First,
receives
Clinic
(Blood
Pathology
This it
problem.
of Mayo
Mayo
Mayo
up to I in 4000
because
of the
tests
ofClinical
“possibly
misleading
magnitude
1981
Journal
that
the
Emeritus,
Taswell,
destruction,” D.C.,
transfusion
pretransfusion
cited
and ofMedicine,
Editor:
I appreciate
ofHuman
6900
of
of hemolytic
10021
recently
brief
and
the rug until
M.D.
School
Mount
New
Editor his
Sinai
Blood
asymptomatic To the
save time
recognition
Richard
The
University
Dr.
University Im
will under
Professor Director
Ph.D.
M. Schroeder
Institute
Much needed.
Avenue
York, New
Traute
think.
are badly
us
who are
Investigative Dermatology
Rockefeller
/230
cross-
institutions,
bankers
by Masouredis, their
not have It is clear and
other
problem
Mayo
reactions.
Professor
Laboratoryfor
would
but they
how to improve
by
screening
blood
of the
Rh-type-specific
patients.
most
desirable,
Mount D. Auerbach,
made and
both
and
this critical
is invited. Arleen
in
by
to determine
we probably
Clinic
less than
learn
ABO
technical given
indictment
specifically
tests
also sweep
finally
a serious
issued
testing,
Mayo
or value
1 in 200 transfused
are not only
tests, it will
clerical
wrong
procedures
a point
than
considerably
of exact
popular
antiglobulin
as done
more
of the
any
the
represents
if we just
more
to
from
also
blood,
all,
doing
albumin
accomplish
course
After much
transfusion
from
FA
compatibility
Registry
unrelated
fold
figure
of currently
is
to eventually
the
ten
the sensitivity
to
a means
by
But
patients,
and
reaction
differs
matching,
breakage
in order
the clinical
and
This
of the registry
FA
establish
in genetics
Correspondence with
is
and
of malignancy.
We ask all of our colleagues in this
FA
fibroblasts,
chromosome
presumptive clinical
of
all
of the features
lymphocytes,
in the disorder,
of
use of a cytogenetic
67: 128, 198 1 ). The all
Masouredis.
of patients
some
by the induced
as possible,
with
diagnosis
diversity
manifest
of FA
error.
us in
International
transfusion
Schroeder,
Registry
Clinical
that
to chemically
as far
International
be confirmed
on the sensitivity
M.
to cooperate
patients.
disorders
may cells
Traute
due to phenotypic
et al. Pediatrics
to ascertain,
an
(FA)
of other
Diagnosis
and
colleagues
maintain
to establish
the occurrence
U.S.A.,
upon
anemia
difficult
FA.
Auerbach,
call
Fanconi
often
Anemia hemolytic
Editor.
We,
of
of the
transto 1:3400
latest Clinic
figure has a
S. P. Masouredis,
M.D.,
Professor
of Pathology
Director,
University
University La Jolla,
Hospital
ofCalifornia. Calif
Blood,
Ph.D.
San
Blood
Bank
Diego.
T-003
92093
Vol. 60, No. 4 (October).
1982
