Jul 19, 2017 - Authenticated. Download Date | 12/1/17 1:23 AM ... lates analysis processes were free from phthalate contamination. The samples obtained were analyzed ... autosampler and pump. Chromeleon software (Version 6.80) was.
Higher phthalate concentrations are associated with precocious puberty in normal weight Thai girls https://doi.org/10.1515/jpem-2017-0281 Received July 19, 2017; accepted October 4, 2017; previously published online November 25, 2017
Abstract Background: The cause of precocious puberty may be associated with genetics and other conditions such as central nervous system (CNS) insults, or the exposure to endocrine disrupting chemicals (EDCs). Phthalates is known to be one of the EDCs and have estrogenic and antiandrogenic activities, and may be associated with advanced puberty. The objective of the study was to determine the association between urinary phthalate metabolites and advanced puberty. Methods: A cross-sectional study was conducted in patients with precocious puberty (breast onset
