Image quality metrics for optical coherence angiography Andrea Lozzi,1,* Anant Agrawal,1 Adam Boretsky,1 Cristin G. Welle,1 and Daniel X. Hammer1,2 1
Center for Devices and Radiological Health, Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring MD 20993, USA 2
[email protected] *
[email protected]
Abstract: We characterized image quality in optical coherence angiography (OCA) en face planes of mouse cortical capillary network in terms of signal-to-noise ratio (SNR) and Weber contrast (Wc) through a novel maskbased segmentation method. The method was used to compare two adjacent B-scan processing algorithms, (1) average absolute difference (AAD) and (2) standard deviation (SD), while varying the number of lateral crosssections acquired (also known as the gate length, N). AAD and SD are identical at N = 2 and exhibited similar image quality for N
