Accepted Article
Impact of Delirium on Patients Hospitalized for Myocardial Infarction: a Propensity Score Analysis of The National Inpatient Sample
Abdullah Abdullah, MBBS, MRCP, MSc 1, George Eigbire, MD1, Amr Salama, MD1, Abdul Wahab, MD1, Mohanad Awadalla, MBBS2, Ryan Hoefen, MD, PhD3, Richard Alweis, MD1,4,5 1- Department of Medicine - Rochester Regional Health, Unity Hospital, Rochester, NY 2- Department of Medicine – University of Massachusetts Medical Center, Worcester, MA 3- Department of Cardiology - Rochester Regional Health, Unity Hospital, Rochester, NY 4 - Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 5- School of Health Sciences, Rochester Institute of Technology, Rochester, New York Corresponding author: A S Abdullah, MBBS, MRCP, MSc.
[email protected] 1555 Long Pond Road Unity Hospital – Rochester Regional Health Department of Medicine Rochester, NY 14626 Cell: +15855030583 Key words: “Myocardial Infarction”, “Delirium”, “Altered mental status”, ICD-9-CM codes, comorbidities. Authors disclosures: None
Abstract Background: Delirium is associated with worse outcomes in critically ill patients. In the subset of patients with myocardial infarction (MI), the impact on clinical outcomes of delirium is not as well elucidated. Hypothesis: Delirium is associated with increased mortality in patients hospitalized for MI Methods: The study used data from the National Inpatient Sample (NIS) 2012 2014, Healthcare Cost and Utilization Project (HCUP). We included discharges associated with the primary diagnosis of MI using the relevant ICD-9-CM codes. The outcome was inpatient mortality between the delirium group and propensity score matched controls without delirium.
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/clc.22972
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Accepted Article
Results: The study included 1,330,020 weighted discharges with MI as the principal diagnosis. Within this cohort, 18,685 discharges (1.4 %) had delirium. Delirium was associated with older age, lower rates of PCI, and increased comorbid conditions. The delirium group had higher mortality: 10.5 % vs. 2.6 %, p
