International School of Advanced Magnetic Resonance Applications in Medicine and Neuroscience (Scuola Internazionale sulle Applicazioni Avanzate di Risonanza Magnetica in Medicina e in Neuroscienze) Director: Prof. Girolamo Garreffa Honorary member of SSFSR and I.E.ME.S.T.
Basic Course announcement:
Magnetic Resonance Methods and Techniques
“Autumn School of Magnetic Resonance Applications in Medicine & Neuroscience”
18 October 2018, Villa Santa Teresa – Bagheria (Pa)
AIMS AND RECIPIENTS The basic course of the “Autumn School of Magnetic Resonance Applications in Medicine & Neuroscience” aims to tackle and develop the principles behind MR methods and techniques. We welcome any participants with at least a three-year university degree such as Radiography, Physics, Chemistry, Engineering and all those (i.e. Radiologists, Radio-oncologists, Oncologists, Neurologists, Neurosurgeons, Radiographers) who, utilize MR applications at different levels, or who want to acquire or expand professional skills by attending one or more course modules since registration to single modules is allowed. The basic course also provides propaedeutic competences towards the advanced course, whose contents will soon be released in detail. The project also offers the opportunity to attend to one or more basic modules to undergraduate students in Physics, Chemistry and Engineering with the opportunity to earn University credits. These opportunities will be regulated by agreements with University Departments approved by the Director of the International School. The admission to the courses will be evaluated by the Chair of SC and applications submitted with also a MR project proposal are preferred. Entries will be assessed on a case-to-case basis by the President of the Scientific Board. The most successful application will be rewarded with a free admission to the course. Some participants might be eligible to a discounted fee, in which case the eligibility will be assessed on a case-to-case basis. The basic course will be propaedeutic to the advanced course which will take place next spring and whose contents will be soon go public and will also include any topics from the previous course that need further discussion.
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REGISTRATION AND CERTIFICATIONS The course will take place from 18 to 21 October 2018 in Bagheria, about 10 km from Palermo, at Villa Santa Teresa (SS 113 Km 246). Members can take advantage of discounts for their stay with conventioned hotels; a shuttle is available to move towards Villa Santa Teresa and the airport of Palermo. The full course registration fee is € 500 but it is also possible to register to single modules only and the registration fee for each single RM1 / RM2 / RM3 / RM4 module is € 100; the registration fee for a single RMSp1 / RMSp2 experimental module is € 150. The members of the SSFSR "Silvia Mascolino" can benefit from a 40% discount on registration fee. Participants (at least two) of the same institution can benefit from a 25% discount on registration fee. Registration form can be downloaded at www.scuolasicilianaradioprotezione.it Registration request and further information can be obtained sending an Email to:
[email protected] and for detailed information about the course programme, contents and objectives:
[email protected] The email subject should read: “Basic Course: Magnetic Resonance Methods and Techniques” The course also offers CME accreditation by the National Agency for Regional Health Services (AGENAS) for the health professionals, also according to the recent decree n. 042/2018 issued by the Regional Health Department of Sicily. At the end of the course, the I.E.ME.S.T. and the “SSFSR Silvia Mascolino” will release participation awards signed by the respective Presidents and Director of the Project “International School of Advanced Magnetic Resonance Applications in Medicine & Neuroscience” indicating the topics discussed. The participant, moreover, might request an additional assessment session which will be run by a committee of experts in the field of Magnetic Resonance; in this case the candidate will provide an original essay on a chosen topic among those discussed in the course. Should the candidates be successful they will obtain another certificate indicating the verified skills; the essay will be published in the Proceedings of the Autumn School and shared on the IEMEST and SSFSR web sites. The committee experts, chosen by the president of the scientific board with the advice of the other members, will be made public on the 10th of September 2018. The handing out of the certificate will cost 100 €
LECTURERS OF THE BASIC COURSE Marcello Alecci Giuseppe Cellini (GE Healthcare, IT); Alessandro D’Aquila (SSFSR) Stefania Della Penna Fabrizio Fasano (Siemens UK, 7 Tesla Cardiff) Angelo Galante Girolamo Garreffa Giuseppe Lazzara (Università di Palermo)
Nunzio Mallia Alfonso Mangione Maurizio Marrale Giacomo Messina Luciano Mirarchi (Siemens, IT) Matteo Milanesi (Canon Medical Systems IT) Paolo Sessa (Philips, IT)
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DURATION AND COURSES SCHEDULING The course will run for a total of 27 hours of lectures, hands-on sessions and finally an assessment, over four days of full-immersion, which are made up of four lecture modules and two hands-on and experimental sessions. Tutoring is also provided. Below is the detailed programme.
DAY 1: Thursday 18 October Lecturers: Mangione, Messina, Lazzara, Alecci, Mallia Module MR1 (8:30 – 13:30) Fundamentals - Basic relevant physics in MR; - Basic relevant chemistry in MR (molecular structures, compounds, chemical shift); - Description of MR Scanner components and parts; - Basic MR Scanner technology and types of magnets; - Static Magnetic Fields and Spatial Gradients; - The Radiofrequency field, coils, types and features.
16:30 – 19:00 Presentation Event of the International School Chairman: Paolo Guzzanti, Journalist and Writer There will be present important guests and the greetings of MR Scientific Community Members, who have already joined the project of the International School will also be video transmitted.
Day 2: Friday 19 October Lecturers: Marrale, Garreffa, D’Aquila, Galante, Della Penna Module MR2 (9:00 – 13:00) MR Image formation - Dynamic Gradients, gradient coils, types and technical parameters; - MR Signal: production and acquisition; - The concept of MR pulse sequence, the contrast and its signal weighting; - MR image formation.
Module MR3 (15:00 – 19:00) MRI and its different modalities, methods of analysis, introduction to advanced methods in clinical practice and research - Main MRI pulse sequences, types and features; - Pulse sequence parameters, their meaning and effect; - Advanced pulse sequences in MRI: DWI, EPI, SWI, MRS, ..; - Research applications fMRI, DTI, multi-modal, multi-parametric MR, data analysis Hybrid-Imaging; - “in vivo” MR Spectroscopy, basic biochemical concepts, tissue metabolites in heath and diseases; - Artifacts in MRI, types and possible causes.
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DAY 3: Saturday 20 October Lecturers: Fasano, Milanesi, Sessa, Mirarchi, Cellini, Mallia, Garreffa, Galante Module MR4 (9:00 – 13:00) MR Safety - General concepts of MR Safety "from low field to high field", state of art and perspectives; - SAR and peripheral nerve stimulation (PNS), sequence parameters involved; - Implanted devices (passive, active), the MR Conditional concept, B1+ RMS; - Patient safety in MR environment, during the scan, the burns risk, the tissue overheating risk (SAR), the peripheral nerve stimulation risk; - Superconducting magnets, liquid Helium and related risks, the quench.
Module RMSp1 (15:30 – 19:30) practical session, hands-on - Static magnetic fields and its spatial gradients (mapping and critical issues); - Test Phantom scan and acquisition, scan parameters selection: analysis of their effects; - generation of main artifacts and explanation; - SAR and related scan parameters.
DAY 4: Sunday 21 October Lecturers: Alecci, Galante, Garreffa, Mallia, Midiri Module RMSp2 (9:00 – 15:00) experimental session and final test - Workbench RF Surface coil mounting and validation; - Workbench RF Volume coil mounting and validation; - SAR and physical aspects related to tissue heating; - The action of dynamic gradients; - Patient Safety in MRI Practice; - Optimization and personalized pulse sequences and diagnostic protocols; - Final discussion, summary of principal topics and conclusions.
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THE PROJECT International School of Advanced Magnetic Resonance Applications in Medicine and Neuroscience ISchool-AMRapp in Medicine & Neuroscience
The project “International School of Advanced Magnetic Resonance Applications in Medicine & Neuroscience” is made up of different editions of basic and advanced courses on applied Magnetic Resonance in Medicine and Neuroscience; it is supported by the Scuola Siciliana di Formazione superiore di Radioprotezione “SSFSR Silvia Mascolino” and by the Euro Mediterranean Institute of Science and Technology (IEMEST), the respective Presidents appointed Prof. Girolamo Garreffa as Director of the Project. Girolamo Garreffa, Physicist, is an honorary member of SSFSR and of IEMEST Scientific Committee, active scientist since 1990 in the field of Applied Physics and in particular on the advanced applications of Magnetic Resonance Methods in Neuroscience. The project involves the participation of scientific Institutions and partners both in the private and public sectors. Moreover, an international conference will be organized every year, with the aim to offer to the participants a concrete opportunity to interact with the leading scientists and learn about cutting edge multidisciplinary topics. The scientific committee (SC) of the project is composed of: ➢ Prof. Girolamo Garreffa (Physicist) ➢ Prof. Marcello Alecci (Physicist) ➢ Dott. Leonardo Angelone (Engineer) ➢ Prof. Alessandro Bozzao (Radiologist) ➢ Prof.ssa Stefania Della Penna (Physicist) ➢ Prof. Angelo Galante (Physicist) ➢ Prof. Walid Kyriakos (Engineer) ➢ Dott. Nunzio Mallia (Physicist) ➢ Prof. Alfonso Mangione (Physicist) ➢ Prof. Maurizio Marrale (Physicist) ➢ Dott. Roberto Miraglia (Radiologist) ➢ Prof. Luca Saba (Radiologist) ➢ Dott. Vincenzo Santoro (Radiographer) ➢ Dott.ssa Rita Vadalà (Radiologist) ➢ Prof. Bruno Zobel Beomonte (Radiologist)
Chairman and Director of the Project Università degli Studi dell’Aquila; U.S. FDA (Silver Spring, MD, USA) Università di Roma “Sapienza” ITAB, Università G. d’Annunzio, Chieti; Università degli Studi dell’Aquila; Harvard University (Boston, USA) ANFEA (National Presidency), SSFSR I.E.ME.S.T. University of Palermo, SSFSR IRCCS ISMETT, Palermo University of Cagliari TSRM PSTRP Professional Association (National Presidency) IRCCS Santa Lucia, Roma Università Campus Biomedico di Roma
The Advisory Board (AB) of the project at the moment is composed of:
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Dott. Brenno Cabella
Istituto de Fisica Teorica - IFT- Unesp, Hospital Das Clinicas - USP (Brasile)
Prof. Francesco Cappello
University of Palermo
Dott. Hans Engels
MR:Comp (Germany) ex MRSafety Director Philips Healthcare
Prof. Giacomo Messina
University of Reggio Calabria
Prof. Massimo Midiri
University of Palermo
Prof.ssa Stefana Milioto
University of Palermo
Dott. Francesco Potito
Chair of “Fondazione Potito”, Campobasso
Prof. Aldo Quattrone
Rector Emeritus of “Magna Graecia” University of Catanzaro
Prof. Robert Mulkern
Harvard University (Boston, USA)
Prof. Stefano Seri
Aston University, Birmingham (UK)
Dott. Luigi Zummo
“Gruppo Karol Strutture Sanitarie” (Presidency), Palermo
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AIMS OF THE PROJECT The courses are designed and structured with the aim to allow the participant to acquire in-depth skills regarding technologies and methodologies in Magnetic Resonance, from clinical practice to scientific research. Thanks to the collaboration with the most affluent scientists in the field and experts from industry, the course will include basic concepts of physics, technology, methodology and MR safety related to the use of Magnetic Resonance methodologies, leading the participant towards adequate knowledge and then move on to acquire additional skills on advanced applications of Magnetic Resonance methods and techniques, now of huge interest in Medicine, Neuroscience, Applied Physics, Biomedical Engineering and Industry. The contents are selected in order to provide, since the start, a thorough and interactive vision of the complex operative scenario of Magnetic Resonance, which, because of the fast-paced technological progress of the recent years, requires those in the field to obtain an ever growing level of competence. The courses are characterized, in particular, by practical sessions, guided by high profile tutors and also with the collaboration of experts of the main industries in the field, all activities are supervised by the Director of the Project. Among the objectives of the Project IS-AMRapp in Medicine and Neurosciences are: the creation of an international network of contacts and skills and the realization of research programs on a national and international scale.
ADVANCED COURSE “Spring School of Advanced Magnetic Resonance Applications in Medicine & Neuroscience” The advanced course will focus on the recent progress in MR methodologies and technologies applied to Brain Investigation and clinical practice with exploring all possible benefits in harmony with the WHO objectives of personalized medicine. These advancements require a constant update of skills and knowledge within the MR field also in terms of quality of investigation and safety of the patient (high field MR, multimodal/hybrid Imaging, MR-HIFU). MR techniques introduced and elaborated in the basic course will be further developed with the collaboration of national and international experts, not only with the aim of good practice but also exploring different new scenarios and applications such as multimodal MRI, MRI-guided focused ultrasound and many others. The great potential of advanced MR diagnostics and how it aids precision medicine will be discussed, as well as high field MR systems (>= 3T)
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