Jun 4, 2012 - Calabar, Calabar, Nigeria. 3. Department of. Biochemistry, Imo State. University .... Preparation of haemoglobin solution: Blood specimens from ...
Journal of Research in Biochemistry
Journal of Research in Biochemistry An International Online Open Access Publication group
Original Research
Anti-aggregation effects of processed yellow and white Garri Aqueous Filtrates on sickle cell Trait Haemoglobin. Authors: Ibegbulem CO1, Nwaogu LA1, Alisi CS1, Igwe CU1, Egbung GE2 and Chikezie PC3. Institution: 1.Department of Biochemistry, Federal University of Technology, Owerri, Nigeria. 2. Department of Biochemistry, University of Calabar, Calabar, Nigeria. 3. Department of Biochemistry, Imo State University, Owerri, Nigeria.
ABSTRACT: Aqueous filtrates of processed yellow and white garri {fried fermentation products of cassava (Manihot esculenta)} were investigated for their effects on the aggregation of sickle cell trait haemoglobin (HbAS), in vitro. Phytochemicals detected in the two filtrates included tannins, catechins, flavonoids, cyanogenic glycosides, β-carotene and thiocyanates. Biomolecules such as amino acids, monosaccharides and ρ-hydroxybenzoic acid (ρ-HBA) were also present. Saponins and cardiac glycosides were not detected in either of the filtrates. The processed white garri aqueous filtrate did not contain β-carotene. Palm oil did not contain cardiac glycosides. The amino acid with the highest (p
