Maik Stiehler, MD, PhD. Orthopaedic Surgeon. Head of Experimental Research
Group. Head of Bone Bank. Department of Orthopaedics. University Hospital ...
Maik Stiehler, MD, PhD Orthopaedic Surgeon Head of Experimental Research Group Head of Bone Bank Department of Orthopaedics University Hospital Dresden Fetscherstr. 74, 01307 Dresden
[email protected] Phone: +49 (351) 458-18188 Fax: +49 (351) 449 210 419
RESEARCH INTERESTS Bone tissue engineering CLINICAL INTERESTS total joint replacement EDUCATION 1995 – 2002 Medical studies at Georg-August-University Göttingen, Germany; Mount Sinai School of Medicine, New York, USA; Harvard Medical School, Boston, USA; University of Berne, Switzerland 1998 – 2002 Scholarship, "Studienstiftung des Deutschen Volkes" 2000 "Förderpreis 2000", Medical Technology Foundation "Family Klee" 2002 – 2006 Resident and research fellow, Department of Orthopaedic Surgery, University Hospital Aarhus, Denmark 2006 Dissertation in the field of nuclear medicine in the departments of Nuclear Medicine, Georg-August-University Goettingen, Germany and PhilippsUniversity Marburg, Germany Title: “Development and pre-clinical evaluation of different peptide-based CCKA, CCK-B/Gastrin and pan-CCK receptor ligands in relation to diagnosis and therapy of CCK-receptor-positive tumours in nuclear medicine.” 2006 Ph.D. defence in the interdisciplinary “Nanoscience and Biocompatibility Project” at the Department of Orthopaedics, Aarhus University Hospital, Denmark and at the Institute of Molecular Biology, Aarhus University, Denmark. Title: “Mesenchymal stem cells for bone reconstruction – molecular and tissueengineering strategies” 2006 – 2010 Resident, Department of Orthopaedics, University Hospital Dresden, Germany since 2008 Leader of local bone bank at Department of Orthopaedics since 2009 Leader of Experimental Research Group at the Department of Orthopaedics Group leader of binational Chinese-German consortium on “Modern tissue engineering concepts for bone regeneration “ since 2010 Consultant, Department of Orthopaedics
SELECTED PUBLICATIONS Book chapters Stiehler M and Günther KP. Epidemiologie der Hüftendoprothetik. In: Arbeitsgemeinschaft Endoprothetik Manual “Hüfte” (Hrsg. U. Holz). (in press).
Stiehler M, Kirschner S, Günther KP. Hip Surface Replacement. In: EFORT textbook, pelvis and hip section. 2010 (in press).
peer-reviewed scientific articles Hertel R, Hempfing A, Stiehler M, Leunig M. Predictors of humeral head ischemia after intracapsular fracture of the proximal humerus. J Shoulder Elbow Surg. 2004 Jul-Aug;13(4):427-33. Stiehler M, Duch M, Mygind T, Li H, Ulrich-Vinther M, Modin C, Baatrup A, Lind M, Pedersen FS, Bunger C. Optimizing viral and nonviral gene transfer methods for genetic modification of porcine mesenchymal stem cells. Adv Exp Med Biol. 2006;585:31-48. Mygind T, Stiehler M, Baatrup A, Li H, Zou X, Flyvbjerg A, Kassem M, Bunger C. Mesenchymal stem cell ingrowth and differentiation on coralline hydroxyapatite scaffolds. Biomaterials. 2007 Feb;28(6):1036-47. Epub 2006 Nov 1. Stiehler M, Lind M, Mygind T, Baatrup A, Dolatshahi-Pirouz A, Foss M, Besenbacher F, Kassem M, Bunger C. Morphology, proliferation, and osteogenic differentiation of mesenchymal stem cells stimulated by Ti, Ta, and Cr surfaces. Journal of Biomedical Materials Research Part A, Nov 2007 [Epub ahead of print]. Stiehler M, Bunger C, Baatrup A, Lind M, Kassem M, Mygind T. Effect of dynamic 3-D culture on proliferation, distribution and osteogenic differentiation of human mesenchymal stem cells. J Biomed Mater Res A, Apr 2008 [Epub ahead of print]. Günther KP, Witzleb WC, Stiehler M, Kirschner S. [Revision surgery of hip resurfacing.] Orthopade. 2008 Jul;37(7):685-94. German. Thieme S, Ryser M, Gentsch M, Navratiel K, Brenner S, Stiehler M, Rölfing J, Gelinsky M, Rösen-Wolff A. Stromal cell-derived factor-1alpha-directed chemoattraction of transiently CXCR4overexpressing bone marrow stromal cells into functionalized three-dimensional biomimetic scaffolds. Tissue Eng Part C Methods. 2009 Dec;15(4):687-96 Bernstein P, Bornhäuser M, Günther K-P, Stiehler M. Knochen Tissue Engineering in der Anwendung am periprothetischen Knochendefekt – eine Standortbestimmung. Orthopade. 2009 Nov;38(11):1029-37. German. Thielemann F, Günther KP, Stiehler M. Influence of overweight and obesity on the musculoskeletal system in children and adults. Adipositas 2010; 4; 26-35. Stiehler M, Seib P, Bernstein P, Rauh J, Goedecke A, Bornhäuser M, Günther KP. Cancellous bone allograft seeded with human mesenchymal stromal cells – a potential GMP-grade tool for the regeneration of bone defects. Cytotherapy (in press). Vater C, Kasten P, Stiehler M. Culture media for differentiation of mesenchymal stromal cells (Acta Biomaterialia, invited review paper, submitted).
MEMBERSHIPS Deutsche Gesellschaft für Orthopädie und orthopädische Chirurgie (DGOOC) 2
Société Internationale de Chirurgie Orthopédique et Traumatologie (SICOT)
REVIEW BOARD MEMBERSHIP Acta Pharmacologica Sinica Acta Biomaterialia Journal of Biomedical Materials Science Journal of Biotechnology Progress Journal of Orthopaedic Research Tissue Engineering
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