Marie Bashir Institute. Tackling Infections, locally and globally sydney.edu.au/mbi
1. Westmead Precinct. Research Group. Arboviruses. Clinical micro lab - ...
Marie Bashir Institute Tackling Infections, locally and globally
Westmead Precinct Research Group
Arboviruses
Clinical micro lab - Paediatrics
Critical Infections (CRE)
Fungal infections (translation)
Institute | Building
ICPMR (Westmead)
The Children’s Hospital Westmead
ICPMR (Westmead)
ICPMR (Westmead)
Key strengths
Reference laboratory for diagnosis, detection and surveillance of medically important arboviruses in the Asia Pacific region. Test development and reagent production for arboviruses and other emerging viral pathogens.
Respiratory and diarrheal virus diagnosis.
Part of Critical Infection CRE Genetic ecology of antimicrobial resistance, particularly genetic associations and relative fluxes via transmission vehicles. Impact of antimicrobials on microflora Whole gut ecology level, (including selection of resistance), and level of mobile genes and their vehicles
Molecular pathogenesis, secretion mechanisms, cell signalling, drug discovery Pathology West Mycology reference lab
PC2/QC2 containment facility, with ability to culture viruses and produce antigens for use in a variety of serologic tests. PCR development.
MALDI TOF Viral cell culture Diagnostic PCR
Sequenom MassARRAY Analyzer 4, iPrep™ Purification Instrument, RotorGene 6000. Rapid molecular typing MALDI-TOF MS
Genetic manipulation of fungi (Cryptococcus neoformans model) using biolistic transformation, mouse and Galleria mellonella (wax moth) infection models Molecular traffic in fungi using fluorescence microscopy
Antimicrobial Cycling study database Antimicrobial resistant clinically important Enterobacteriaceae
Cryptococcal culture collection Other fungal culture collection
Jon Iredell | Sally Partridge | Belinda Roychoudhry | Masrura Kabir
Tania Sorrell | Wieland Meyer | Julie Djordjevic | Sharon Chen | Catriona Halliday | Tom Olma Sophie Lev
Equipment models
Datasets Strainbanks Senior people Post-docs PhD Students Other people Other resources
Bordatella species diagnosis
Reference and prototype strains, strains isolated from clinical samples. Linda Hueston
Alison Kesson | Alex Outhred | KinChuen Leung
Andrew Ginn | Muhammad Kamruzzman | Shoma Mohsin | Carola Venturini | Alicia Fajardo-Lubian Kaitlin Tagg | Ruwan S | Jen Kok | Alex Agyekum Emily Mascord | Ramona Negre | Thrift Henderson
Chayanika Biswas | Cecilia Li | So Young (Grace) Chen Desmarini Desmarini |Christabel Wilson | Pierre Juillard
sydney.edu.au/mbi
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Marie Bashir Institute Tackling Infections, locally and globally
Westmead Precinct (continued) Research Group
HIV Laboratory
Influenza
Medical Entomology
Neuroimmunology Antibody Research
Institute | Building
ICPMR (Westmead)
ICPMR (Westmead)
ICPMR (Westmead)
The Children’s Hospital Westmead
Key strengths
Viral Diagnostics Antiviral resistance testing
WHO collaborating centre
Reference laboratory for all medically important arthropods (e.g. mosquitoes, bed bugs, ticks, lice), the pathogens they transmit & control/management strategies Medical Maggot Program Science communications (social and traditional media)
Autoantibody methodology Encephalitis Autoimmune brain disease CNS demyelination
PC4 Laboratory Cell culture AQIS serology laboratory
Real time platforms, molecular subtyping of influenza, scope for neuraminidase resistance testing. Testing for other respiratory viruses
Arthropod (mostly mosquito) collecting equipment, mosquito, fly and bed bug laboratory colonies, medical entomology library, microscopes (inc. macro photography)
Autoantibody methodology FACS Neuronal culture Cell based assays
Clinical specimens Viral isolates
Influenza A & B culture collection from 2000 on wards, other respiratory viruses
Medical Entomology reference specimens NSW Arbovirus Surveillance Program data
Serum and CSF databases of human CNS inflammation Encephalitis cohorts (Serum and CSF)
Dominic Dwyer | Men McPhie | Jen Kok | Mala Ratnomohan
Dominic Dwyer | Jen Kok | Mala Ratnamohan | Ken McPhie
Cameron Webb | Stephen Doggett | Merilyn Geary | Cheryl Toi
Russell Dale | Fabienne Brilot
Equipment models
Datasets Strainbanks Senior people Post-docs
Fabienne Brilot
PhD Students
Eleanor Hitchen | Jesse Lay | Jen Kok
Other people Other resources
Clinical antiviral and vaccine trials unit
David Lilly | Kai Dang | Nur Abu Kassim John Clancy (mosquito taxonomist), John Haniotis (arbovirologist)
Darshi Ramanathan | Esther Tantsis | Sekhar Pillai | Shekeeb Mohammad Vera Merheb
sydney.edu.au/mbi
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Marie Bashir Institute Tackling Infections, locally and globally
Westmead Precinct (continued) Research Group
Salmonella
Sexual health
Tuberculosis (CRE)
Institute | Building
ICPMR (Westmead)
Parramatta HIV/STI clinic
ICPMR (Westmead) The Children’s Hospital Westmead*
Key strengths
NSW Enteric Reference Laboratory
HIV non-B subtypes and clinical trials Anal cancer and HPV Non-gonococcal urethritis/Mycoplasma Adolescent Sexual Health and HPV vaccine decision aids Expanded rapid HIV & HCV testing among dental & pharmacy staff Health promotion among MSM
NSW Mycobacterium Reference Laboratory Part of NHMRC TB CRE Epidemiology, clinical & operational TB research*
Equipment models
Datasets Strainbanks
PC3 and PC4 Laboratory Ion Torrent PGM and pipelines for Salmonella sequencing and analysis MLVA genotyping of Salmonella Typhimurium
PC3 and PC4 laboratory Ion Torrent PGM and pipelines for Mycobacteria sequencing MIRU-5 genotyping of MTB, phenotypic and molecular testing of drug susceptibility
Strain bank of bacterial enteric pathogens: including Salmonella, Shigella, Vibrio, Listeria monocytogenes and enterohaemorrhagic Escherichia coli
General Practice Database (BEACH GP database with Family Medicine Research Centre)
DNA extracts of M.tuberculosis from all culture-confirmed cases in NSW and ACT Working on National Child TB registry*
Vitali Sintchenko | Peter Howard
Deborah Couldwell | Spring Cooper | Richard Hillman | Catriona Ooi | Anthony Santella | Shailendra Sawleshwarkar | Rick Varma Elizabeth Hayles | Natalie Hamam
Vitali Sintchenko | Grant Hill-Cawthorne | Peter Jelfs | Ben Marais | David Isaacs
Senior people Post-docs
Qinning Wang | Michael Roper
PhD Students Other people Other resources
Cristina Sotomayor
Nadine Holmes | Elena Martinez Ulziijargal Gurjav | Alex Outhred
sydney.edu.au/mbi
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