1Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, ... Center, Tel-Hashomer, Israel and 3Sackler School of Medicine, Tel Aviv ...
Journal of Perinatology (2007) 27, 77–81 r 2007 Nature Publishing Group All rights reserved. 0743-8346/07 $30 www.nature.com/jp
ORIGINAL ARTICLE
Maternal serum adiponectin levels during human pregnancy S Mazaki-Tovi1,3, H Kanety2,3, C Pariente2, R Hemi2, A Wiser1,3, E Schiff1,3 and E Sivan1,3 1
Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel; 2Institute of Endocrinology, Sheba Medical Center, Tel-Hashomer, Israel and 3Sackler School of Medicine, Tel Aviv University, Tel Aviv, Tel-Hashomer, Israel
Objective: Pregnancy is a unique situation characterized by insulin resistance. The role of adiponectin, an insulin-sensitizing hormone, has not been completely clarified during pregnancy. The aim of this cross-sectional study was to evaluate adiponectin levels during pregnancy and postpartum.
Study design: Adiponectin and leptin levels were tested in 80 pregnant women, 20 in each trimester (mean gestational age 10.5±1.9; 19.3±4.9; 39.3±0.8 weeks,) as well as 4 days postpartum. Results: Adiponectin levels during first (13.3±3.6 mg/ml), second (12.6±4.4 mg/ml) and third trimester (11.2±3.7 mg/ml) did not differ and were significantly higher than postpartum levels (8.8±2.1 mg/ml; P
