Purpose: To compare posterior corneal elevation (PCE) changes and corneal biomechanical ... At 12 months, PCE change was greater in FS-LASIK than SMILE.
MiR expression profiles of 12 pituitary tissue specimens. (8 NFPA ... to miR-. Base Release 15.0 representing hairpin precursor miRs ... Members of this family, activin, TGFb and bone ..... 181a, miR186, miR-708) did not differ significantly in.
Aug 8, 2012 - in the pathological process of Klinefelter syndrome. Further ... or focused on the character of microRNAs in Klinefelter syndrome until now.
Purpose: To evaluate and compare corneal topographic changes following pars plana vitrectomy with the 23-gauge (G) and 25-G transconjuntival sutureless vi-.
Oct 29, 2013 - lenticule extraction (SMILE) and femtosecond LASIK (femto-LASIK). Design: .... (indicating no problems) to four (indicating a significant problem). ..... Wei S, Wang Y (2013) Comparison of corneal sensitivity between FS-LASIK.
with the handheld ultrasound pachymeter (USP), ultrasound biomicroscopy ... central corneal thickness, ultrasound pachymetry, ultrasound biomicroscopy,.
Oct 18, 2010 - are cytoplasmic foci in mammalian cells enriched in the GW182 protein .... pore, Billerica, MA) to isolate small RNAs (,300 nt). Small ..... MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding).
Jan 3, 2015 - In addition to these findings, another study showed that smoking may inhibit or suppress the triggering factors of keratoconus and lead to a.
Apr 27, 2015 - RESEARCH ARTICLE. MicroRNA Transcriptome Profile Analysis in. Porcine Muscle and the Effect of miR-143 on the MYH7 Gene and Protein.
miRNA modules a b hsa-miR-147 hsa-miR-296 hsa-miR-215 hsa-miR-7 hsa-miR-130b hsa-miR-23b hsa-miR-105 hsa-miR-133a hsa-miR-147 hsa-miR-206.
Aug 8, 2013 - [35] found that miR-32 and its target SLC45A3 regulate the lipid metabolism of oligodendrocytes and myelin. As far as we knew, this is the first ...
Molecular Vision 2013; 19:1815-1825 Received 11 January 2013 | Accepted 3 August 2013 | Published 8 August 2013
MicroRNA profile comparison of the corneal endothelia of young and old mice: implications for senescence of the corneal endothelium Xiaowen Zhao, Yusen Huang, Ye Wang, Peng Chen, Yang Yu, Zicheng Song State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China Purpose: To identify critical microRNAs (miRNAs) that play important roles in regulating the aging of corneal endothelial cells in mice aged 10–13 weeks and 2 years. Methods: We collected the corneal endothelia from 30 mice aged 10–13 weeks and 30 mice aged 2 years. The samples were pooled into six groups (Y1, Y2, Y3 and S1, S2, S3). Each group comprised corneal endothelia from 10 mice, and these six groups were used for a genome-wide miRNA microarray study. The expression levels of eight selected miRNAs were further validated independently by quantitative reverse transcription polymerase chain reaction (qRT-PCR). Target genes were predicted using a computational approach due to their base-pairing rules between miRNA and messenger RNA target sites. The locations of binding sequences were within the target’s 3′ untranslated regions (UTR), and the conservation of target binding sequences occurred within related genomes. Additional gene ontology and signaling pathway analyses were performed using bioinformatics tools. Results: Twenty-seven miRNAs (7 upregulated and 20 downregulated) were found to be differentially expressed (fold change >2, p value