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Function: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains; together with the common gamma chain (IL2RG); constitute the high-affinity IL2 ...
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Name:Anti-IL2RA Rabbit Polyclonal Antibody

Catalog: TA323669

Product Data Sheet - ANTIBODY Components:

• Anti-IL2RA Rabbit Polyclonal Antibody (TA323669)

Amount:

100ul

Immunogen:

Synthetic peptide corresponding to a region derived from 260-272 amino acids of Human interleukin 2 receptor, alpha

Host:

Rabbit

Isotype:

IgG

Species Reactivity:

Human, Mouse, Rat

Guaranteed Applications:

IHC

Suggested Dilutions:

ELISA: 1:1000-10000, IHC: 1:25-100

Concentration:

1.2mg/ml

Buffer:

PBS pH7.3, 0.05% NaN3, 50% glycerol

Purification:

Antigen affinity purification

Storage Condition:

Shipped at -20C. Upon delivery store at -20C. Dilute in PBS (pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.

Target Target Name:

Homo sapiens interleukin 2 receptor, alpha (IL2RA)

Alternative Name:

CD25; IDDM10; IL2R; p55; TCGFR

Database Link:

NP_000408 Entrez Gene 3559 Human Entrez Gene 16184 Mouse Entrez Gene 25704 Rat

Function:

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains; together with the common gamma chain (IL2RG); constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor; while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein; soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated; but the significance of

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. © 2015 OriGene Technologies, Inc.

9620 Medical Center Dr., Suite 200, Rockville, MD 20850

each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. © 2015 OriGene Technologies, Inc.

9620 Medical Center Dr., Suite 200, Rockville, MD 20850

Validation Data

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human liver cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffinembedded Human liver cancer tissue using IL2RA antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200)

* More validation images may be available on our website: http://www.origene.com/antibody/TA323669.aspx

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. © 2015 OriGene Technologies, Inc.

9620 Medical Center Dr., Suite 200, Rockville, MD 20850