Control/Tracking Number: 2012-SS-A-15626-AHA Activity: Abstract Current Date/Time: 6/6/2012 12:23:13 PM Inflammatory Burden Of Peri-Coronary Adipose Tissue May Affect Plaque Destabilization In Patients With Non ST Segment Myocardial Infarction
Author Block: Tomasz Mazurek, Malgorzata Kobylecka, Janusz Kochman, Krzysztof Filipiak, Leszek Krolicki, Grzegorz Opolski, Medical Univ of Warsaw, Warsaw, Poland Abstract: Background: Extravascular expression of inflammatory mediators may adversely influence coronary lesion formation and plaque stability. Maximal standardized uptake value (SUV) of 18-fluorodeoxyglucose (FDG) detected by positron emission tomography in peri-coronary adipose tissue (PVAT) has been shown to be greater in patients with stable coronary artery disease, than in controls, and to correlate with % of coronary stenosis. We sought to investigate, whether PVAT may influence plaque composition in Non ST Segment Myocardial Infarction (NSTEMI) patients. Methods: 36 coronary arteries (LM, RCA, LCX, LAD) have been investigated in non-diabetic patients with moderate and low risk NSTEMI (GRACE
