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Control/Tracking Number: 14-A-8391-ACC Activity: ACC Abstract Current Date/Time: 11/12/2013 4:58:00 AM Short-term Outcomes In Coronary Artery Disease Patients With Multi-Lesion Disease Implanted With Multiple Bioabsorbable Vascular Scaffolds

Author Block: Apurva Patel, Roosha Parikh, Anish Chandarana, Parloop Bhatt, Milan Chag, Satya Gupta, Hemang Baxi, Vineet Sankhla, Mehul Dudhasia, Urmil Shah, Keyur Parikh, Care institute Medical Sciences(CIMS), Ahmedabad, India, Cleveland Clinic Foundation, Cleveland, OH, USA Abstract: Background: ABSORBTM bioabsorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, CA, USA) provides transient scaffolding and everolimus drug delivery. There is limited data on its use in multi-lesion coronary artery disease (CAD). We studied the 30-day outcomes in 21 such patients who were implanted with multiple ABSORB BVS. Methods: A total of 21 patients underwent PCI procedure using BVS at a tertiary hospital , Western India from 12/1/2012 to 10/1/2013 who had multi-lesion CAD in at least two different native coronary lesions treated by individual stenting with one or more stent in each lesion. Demographic and clinical parameters were obtained. Primary end-point was Major Adverse Cardiac Events (MACE) at 30 days. Results: Of the 21 patients assessed (Mean age 53 years, 85.71%( 18) Males), 52.38% (11) had Hypertension, 38.09% (8) had Diabetes, 19.04% (4) had prior history of Percutaneous Coronary Intervention (PCI). Total 61 lesions were identified, 96.7% (59) lesions had > 80% stenosis, LAD 49.2% (30), RCA 29.5% (18), LCX 21.3% (13), 23.8% (5) patients had single vessel disease, 57.14% (12) patients had double vessel disease and 19.04% (4) patients had triple vessel disease, all of which were treated with BVS (Average stent per patient 2.90, with range of 2-6 BVS per patient ). At 30 days, MACE rates were 9.52% with 2 patients having Scaffold(stent) Thrombosis , related to technical issues: under expansion & possible damaged BVS while crossing during original implantation with both successfully managed by balloon intervention only. 71.5% (15) patients had excellent, 14.3% (3) had very good, 9.5% (2) patients had good and 4.7% (1) patients had fair Quality of Life (QOL) which was assessed using standard SF-36 questionnaire at 30 day telephonic follow-

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up. Conclusion: At 30 days, Bioabsorbable scaffolds show good results in patients with multi-lesion CAD. It is a novel approach, without limitations of metallic drug eluting stents like long-term dual anti-platelet therapy, metal jackets from multiple metallic stents, and after 1 year the artery being in natural state future intervention including Re-PCI or bypass surgery is easier. However, long term efficacy and safety still needs to be assessed. : Category (Complete): 40. TCT@ACC-i2: Coronary Intervention: Lmain, Multivessel, Bifurcation Prevention Pathway Abstracts (Complete): Keyword (Complete): Revascularization, multivessel ; Coronary artery disease, multivessel ; Stent, bioabsorbable Institution Information (Complete): *Responsible Institution 1: : Care institute Medical Sciences(CIMS) *City: : Ahmedabad *Country: India Responsible Institution 2: : Cleveland Clinic Foundation City: : Cleveland State: Ohio Country: USA * : No * : No

Presentation Preference (Complete): Poster Presentation Only Payment (Complete): Your credit card order has been processed on Saturday 9 November 2013 at 1:55 PM. Status: Complete Need Technical Assistance? OASIS Helpdesk American College of Cardiology 2400 N Street, NW Washington, DC 20037

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