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Essentially, the main vascular pathology of NAION is focused on ischemia of the anterior lamina cribrosa around the optic disc and metarterioles of the posterior ...
Optic disc perfusion in ischemic optic neuropathy

·Clinical Research·

Optical coherence tomography angiography of optic disc perfusion in non-arteritic anterior ischemic optic neuropathy Jia-Wen Ling1,2, Xue Yin1, Qian-Yi Lu1, Yi-Yi Chen1, Pei-Rong Lu1 1

Department of Ophthalmology, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China 2 Department of Ophthalmology, the Third People's Hospital of Zhangjiagang, Zhangjiagang 215600, Jiangsu Province, China Correspondence to: Pei-Rong Lu. Department of Ophthalmology, the First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou 215006, Jiangsu Province, China. [email protected] Received: 2017-02-10 Accepted: 2017-05-11

Abstract

● AIM: To compare the optic disc blood flow of non-arteritic ischemic optic neuropathy (NAION) eyes with normal eyes. ● METHODS: The optic disc blood flow densities of diagnosed non-acute phase NAION eyes (21 eyes, 14 individuals) and normal eyes (19 eyes, 12 individuals) were detected via Optovue optical coherence tomography angiography (OCTA). The optic disc blood flow was measured via Image J software. Correlations between optic disc perfusion and visual function variables were assessed by linear regression analysis. ● RESULTS: The average percentage of the optic disc nonperfusion areas in the non-acute phase NAION patients (17.84%±6.18%) was increased, when compared to the normal control eyes (8.61%±1.65%), and the difference was statistically significant (P