P=2e-3 P=7e-3 P=1e-3 P=0.53 P=7e-8 P=6e-3 - PLOS

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Johnson et al.,. A Genome-wide Screen for Genetic Variants that Modify the Recruitment of REST to its Target Genes. H1 ES Cells rs11159355. pRE1-18.
Supplementary Figure S3 Johnson et al., A Genome-wide Screen for Genetic Variants that Modify the Recruitment of REST to its Target Genes

H1 ES Cells

0.5

P=2e-3

0.4

R e a d D e n sity

Fraction Bound

rs11159355 pRE1-18 NRXN3

0.3 0.2 0.1 0 pR E 1-18

400 350 300 250 200 150 100 50 0

P=0.53

0 10 20 30 40 50 60 70 P o sitio n (b p )

0.8

P=7e-3

0.7 0.6

R e a d D e n sity

Fraction Bound

rs12244739 pRE1-53 GPR26

0.5 0.4 0.3 0.2 0.1 0 pR E 1-53

400 350 300 250 200 150 100 50 0

P=7e-8

0 10 20 30 40 50 60 70 P o sitio n (b p )

P=1e-3

0.6

R e a d D e n sity

0.5 Fraction Bound

rs3979 pRE1-56 ADRA2C

0.4 0.3 0.2 0.1 0 pR E 1-56

400 350 300 250 200 150 100 50 0

P=6e-3

0 10 20 30 40 50 60 70 P o sitio n (b p )