Efek Anti Agregasi Trombosit dari Ekstrak Bawang Putih (Alium sativum) pada
Tikus. Author : M. Soedjak.N(1), Sri Agus Sudjarwo(1), Koerniasari(2). Abstract :.
Efek Anti Agregasi Trombosit dari Ekstrak Bawang Putih (Alium sativum) pada Tikus Author : M. Soedjak.N(1), Sri Agus Sudjarwo(1), Koerniasari(2) Abstract : The effect of garlic extrac on platelet agregation and bleeding time in rat was studied. The rats were divided into treatment (garlic extract), comparative (aspirin) and control groups. The treatment with garlic extract or aspirin significant inhibited platelet aggregation and prolong the bleeding time compared from control group.. However the treatment with garlic extract was less effective than treatment with aspirin. The treatment with garlic extract inhibited platelet aggregation and prolong the bleeding time in a concentration-dependent manner. These results suggest that garlic extract inhibited platelet aggregation and prolong the bleeding time via inhibitor of the synthesis thromboxane A2. (end)
