Page 1 Indian Vet. J., January, 2006; 83 : 110 - 111 ...

lhdianVet．J．，January，2006；83：110・111

CHEMOSTERILIZATlON OF MALE DOGS i．Canpolat，S．KiliclandA．Cevik2

1DepartmentofSurgeIyand2Pathol0gy VeterinaryFacuItyFi伯tUniversity23119， EIazIg−nJkey （Received：19・10−2004：Accepted O6“12−2004）

ChemosteriIizationistriedonthe COnCentrationestimationwasperformedprior

malesofsomespeciesincludingmonkeys，tOand7・15130and60daysafter hamsters，rabbits．ratsanddogsby．intratesticuIardrug叫eCtion・ThesexuaI intratesticular叫eCtionofseveralagents desireandinfer冊yioftheanimalswere

（Kar，1961；KaretaI．，1965；lmmegart，teStedbyallowlngthemtomatewithabitchl 2000）．Thepurposeofthestudywasto atOeStruSCyCle・Twodogsfromeachgroup determinetheefficacyofintratesticu−ar Wereeuthanaisedondays7・15・30and60 injectionofethanolandcalciumchIorideon afterdrugmjeCtionforhistopathoIogIC ChemosteriIizationofmaledogs・    eValuationoftheirtesticles・Statistical

anaIyseswasperformedwithstudentt−teSt．

MaterialsandMethods

ResuitsandDiscussion

SixteenmaIedogs，24−44kgbody Weight，2−4yrsold，WereuSed・Theywere  lttSticularswe冊gwasevidentinall dividedrandomIyintotwoequalgroups dogsofbothgrOuPSfellcWing向ectionand CailedEG（ethanoIgroup）andCCG（Caicium reaChedpeakwithin48hours・While Chloridegroup）．AfterlmilocaIanaesthetic teSticularvoiumedecreasedsignificantIy一

（Citanest2％）injectjons，tenmiabsolute（P＜0・05）inEGaHer3weeks，noSignificant ethan010rtenmlcalciumchlorideat30％ ChangeoccuredinCCG（P＜0．05）．The COnCentrationwereInjeCtedintratesticuIar−y・teSticIesunde…entatrOphyatthe60thday Trans−SCrOtaltesticularultrasonographywasinEGbutmarkedalterationwasnot

Performedwith7．5−5Mhziinearprobe（Pie ObservedinCCG・In3EGcases．testicular medicaL ScanVet−200）pri°rtOthe SWe冊gwasassociatedwithfistulaand intrastesticularInjectionandonceadayfor Sloughingofthescrotalskin・Atnecropsy． aweekfoIIowlngintrastesticu−ar…jection theirtesticulartissuesweref。undtobe

andthenatoneweekinteNaIsupt060days・neCrOtized with muddy texture・ During this examination， the Histopathclog−calexaminationreveaied ultrasonographicappearanceofatestiswas COaguIativenecrosis・TheseprobIemswere

evaluatedanditSheight（h），Width（W）amd nOtreCognizedinanyCCGcases・ Iength（l）wasmeasured．Thevclumeofthe tesliswasestimatedusingVolume＝何6） Ultrasonographicexamination°neday X（WXhxl）equation．Serumtestosteroneafterdruginjectonrevealedthetesticular

tissueofaiIanimalsofbothgroupsto 圃        iVJJanua，y2006

田 l．canpoiatefaI．

PreSentdiffuseechotextureandincreased

calciumchloride．

echogenicity・Thenecrotizedregionswere differentiateduItras。nOgraphicallyfromthe

ResuIts suggestthatintratesticuiar

normaItesticulartissuewithhypoechogenic

lnJeCtionofproperdoseofabseluteethanoI

appearance・lnthisstudy，meanbaseline

COuldbeane的ctivemethodfornonsurglCaI

Value ofserum testoteroneconcentratjon

SteriiizationofthemaIedogs・

WaSdeterminedas35．2±2．6pg／mIwhich

References

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0ptimum effective dose of caicium Chiorideinratwasconsideredtobebetween 10−20mg，however．themostdesiredresuIt Obtained

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etaIっ2002）．TheseauthorsandSamanta （1998）found marked necrosisin the

Seminiferous tubules during the use of

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PUBLICAJlONREcEiVED TextbookonNecropsyandHistopatIl0−09−cal

Techniques‥ByD・GopaIaKrishnaRao，Dean，Veterinary

Coilege・Bidar，Kamataka・PubIishedbyAcademapubLishers，

1329，MaIiwara，VaidwaraNaiSarak，Delhi−110006．First

Edn・2005．Page269，Price：Rs．200l−

IVJJanuary2006

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