Pharmacometabolomics in Early‐Phase Clinical Development

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Apr 29, 2016 - use of pharmacometabolomics in early−phase drug devel- opment, and conclude with recommendations for applica- tions in clinical trials.
Citation: Clin Transl Sci (2016) 9, 128–138;  C 2016 ASCPT. All rights reserved

doi:10.1111/cts.12396

REVIEW

Pharmacometabolomics in Early-Phase Clinical Development T Burt1,∗ and S Nandal2

INTRODUCTION Pharmacometabolomics is an emerging field that uses the body’s complement of metabolites to identify individuals likely to experience treatment or adverse effects. Nevertheless, review of clinicaltrials.gov reveals that