Physio Syllabus Fall 2012 - Kalamazoo College

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PHYSIOLOGICAL PSYCHOLOGY PSYC 425/Fall 2012 MWF 11:50 a.m. to 1:05 p.m. Olds Upton #412 Professor:

Dr. Robert Batsell Office: Olds-Upton #403B E-mail: [email protected] Office Telephone: 337-7032 (or in emergencies: 743-8050)

Office Hours: MWF 10:00-11:00 a.m. and by appointment Teaching Assistant: Dana Allswede

Office: OU

Recommended Textbook: Breedlove, S.M., Rosenzweig, M. R., & Watson, N. V. (2007). Biological Psychology (Fifth Edition). Sinauer. Required Additional Readings: Colapinto, J. (2000). As nature made him. Harper Collins Publishers. Journal Articles (see pp. 4-8) Class List-serve: [email protected] I. COURSE SUMMARY Physiological psychology examines the interactions between the brain and behavior. In this class, we isolate the physiological processes that take place inside the body whenever behavior occurs. The assumption underlying this science is that for every behavioral event--every action, thought or feeling--there is a corresponding physical event or series of events taking place in the body. During this quarter, we will focus on a variety of topics including: the structure and function of neurons, neuroanatomy and function of the brain, behavioral neuroscience, cognitive neuroscience, affective neuroscience, and assorted special topics. By the end of this course, students should be able to think about an organism’s behavior on three levels (cellular, structural, and systems/behavioral).

2 II. GRADING. There are a total of 400 points available in this class. A 10% grading scale will be used in which students who score over 360 points will earn an ‘A,’ students who score between 320 and 359 will earn a ‘B,’ students who score between 280 and 320 will earn a ‘C,’ and so forth. Tests (4 Total) = Article Reviews (100 pts) =

350 50

A. Tests. Four tests will be given throughout the semester. The test format will include fill-in-the-blank, short-answer, and essay questions. The tests will cover the material presented in class and from the book chapters designated on the syllabus. Moreover, each test will include questions that are taken from book material that is not discussed in lectures. Please note that all exam dates are clearly marked on the syllabus, and they will be given on those dates. Students are required to abide by the Kalamazoo College Honor Code for all of their work in this class. Tests 1 and 2 are worth 75 points each and Tests 3 and 4 are worth 100 points each. B. Article Review Assignments: There are 4 randomly scheduled journal articles readings. For a paper review, the class will self-divide into small groups or pairs of students, and each group/dyad will complete the review sheet. One or two of these review sheets may be completed in class, but to facilitate a meaningful discussion of the article, the majority of the review sheets will be completed out of class before the scheduled class period. The questions on the review sheet will cover information such as the hypothesis, methods, and results of the research. Moreover, key questions will cover the implications of the research, not only for science but for society as well. Please note that spelling, grammar, and economical presentation of material will all be considered in determining the student’s grade. Plagiarism is not tolerated. The article review assignments will range in value from 12 to 15 points for each member of the group. III. ACCOMMODATIONS. A. Student Athletes. Student athletes who have university permission to miss classes or tests need to inform the instructor before they miss the assignment. B. Cultural/Religious Holidays. Kalamazoo College provides reasonable accommodations for observing religious or cultural holidays. Students can be excused from class to participate in these religious/cultural activities, but they will be responsible for getting all assignments and turning in course work. It is the student's responsibility to contact the faculty member in a timely manner to arrange for appropriate accommodations. C. Students with Disabilities. Kalamazoo College provides reasonable accommodations for students with disabilities. It is the student's responsibility to contact the office of the Dean of Students [337-7209] in a timely manner to arrange for appropriate accommodations.

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IV. CLASS RULES. A. Honor System. This course will operate in accordance with the Kalamazoo College Honor System: a responsibility for personal behavior, independent thought, respect for others, and environmental responsibility. Students who are caught cheating or plagiarizing will receive a zero for that assignment, will be referred to Student Services, and may fail the class. Students who download papers or any information from the Internet without citing the source may receive an F in this course. B. Attendance. Attendance will not be taken in this class; but students are expected to attend the scheduled classes. Many of the test questions will come from class lectures and are not in the book. It should be noted that students who have been successful in this class in the past have adopted the strategy of reading the book prior to lecture, attending the lecture, and then rereading the text over the corresponding material. C. Classroom Behavior. The Kalamazoo College Honor Code applies to classroom behavior as well as other types of interpersonal interactions on campus; “respecting others” includes respectful behavior in class. Although Kalamazoo College is committed to respecting fundamental principles of freedom of speech, including even controversial positions taken in class, all types of speech and behavior must be balanced with principles of appropriate classroom behavior. It is ultimately the faculty member who controls the classroom, and if a situation develops in which, in the opinion of the faculty member, the class is being disrupted, the faculty member has the ultimate right to ask a student to leave the class. Longer-term solutions to these problems will be dealt with according to College procedures. Also, the presence of electronic devices is distracting to the professor and other students. Cell phones should be silenced before class and in-class texting may be met with sarcasm, ridicule, and prolonged verbal abuse. D. Make-up Policy. If you know that you are going to miss an assignment (test or paper) for any reason, it is the responsibility of the student to contact the professor BEFORE the assignment is due. Makeup assignments may not be given if prior warning (and the professor’s consent) has not occurred.

4 Physiological Psychology Course Outline Fall 2012 SECTION #1: AN INTRODUCTION TO PSYCHOLOGY & BEHAVIOR Week #1: Introduction to Class Sept 10 (Mon)

Introduction to Class & Field of Neuroscience

Mobbs, D., & Watt, C. (2011). There is nothing paranormal about near-death experiences: How neuroscience can explain seeing bright lights, meeting the dead, or being convinced that you are one of them. Trends in Cognitive Science, 15, 447-449. http://tiny.cc/65vujw Sept 12 (Wed)

Brain Evolution [Breedlove et al., Ch. 1 & 5]

Sept 14 (Fri)

Methods of Studying the Brain [Breedlove et al., Ch. 5]

Week #2: Molecular & Cellular Neuroscience Sept 17 (Mon)

Neuronal Transmission [Breedlove et al., Ch 2 & 3]

Fields, R. D. (2004, April). The other half of the brain. Scientific American, 54-61. http://tiny.cc/v4vujw Sept 19 (Wed) Ch. 3 & 4]

Neuronal Transmission & Psychopharmacology [Breedlove et al.,

Sept 21 (Fri)

TEST #1

5 SECTION #2: Organization of the Nervous System & Brain Functioning Week #3 Sept 24 (Mon)

Organization of the Nervous System: Subcortical Regions

Sept 26 (Wed)

Organization of the Nervous System: Cortical Regions

Mason, M. P. (2008). An insult to the brain. Head cases. (pp. 65-72). Farrar, Strauss, Giroux: New York. http://tiny.cc/j5vujw Mason, M. P. (2008). Rob Rabe cannot cry. Head cases. (pp. 73-96). Farrar, Strauss, Girou: New York. , http://tiny.cc/76vujw Mason, M. P. (2008). The hospital in the desert. Head cases. (pp. 224-244). Farrar, Strauss, Girou: New York. Sept 28 (Fri)

Challenges to Localization of Function

Doidge, N. (2007). Midnight resurrections: Stroke victims learn to move and speak again. The Brain that Changes Itself (pp. 132-163). Viking, New York. http://tiny.cc/31vujw Week #4:

Brain Functioning (Cont’d)

Oct 1 (Mon)

Neuropsychology

Sacks, O. (1970). The man who mistook his wife for a hat. The man who mistook his wife for a hat and other clinical tales. (pp. 8-22), HarperPerrenial, New York. , http://tiny.cc/bawujw Oct 3 (Wed)

Decision Making & Morality in the Brain

Oct 5 (Fri)

Decision Making & Morality in the Brain

Burns, J. M., & Swerdlow, R. H. (2003). Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign. Archives of Neurology, 60, 437-440. http://tiny.cc/r0vujw Anderson, S.W., Bechara, A., Damasio, H., Tranel, D., & Damasio, A.R. (1999). Impairment of social and moral behavior related to early damage in human prefrontal cortex. Nature Neuroscience, 11, 1032-1037. http://tiny.cc/ezvujw Dolan, R.J. (1999). On the neurology of morals. Nature Neuroscience, 11, 927-929. http://tiny.cc/n2vujw Oct 10 (Mon)

TEST #2

6 SECTION #3: Behavioral Neuroscience Week #5: Physiological Substrates of Learning Oct 10 (Wed)

Long-term Potentiation [Breedlove et al., Chp 13]

BE SURE TO INCLUDE M ZETA MAINTAINING MEMORY HERE Oct 12 (Fri)

FALL BREAK: NO CLASS!

Oct 15 (Mon)

Physiological Substrates of Learning

Tang, Y., Shimizu, E., Dube, G. R., Rampon, C., Kerchner, G. A., Zhuo, M., Liu, G., & Tsien, J. Z. (1999). Genetic enhancement of learning and memory in mice. Nature, 401, 63-69. http://tiny.cc/g3xujw Oct 17 (Wed)

Physiological Substrates of Learning (Continued)

Ressler, K. J., Rothmaum, B. O., Tannenbaum, L., Anderson, P., Graap, K., Zimand, et al. (2004). Cognitive enhancers as adjuncts to psychotherapy: Use of DCycloserine in phobic individuals to facilitate extinction of fear. Archives of General Psychiatry, 61, 1136-1144 , http://tiny.cc/p6vujw Oct 19 (Fri)

Sex: As Nature Made Him

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Week #6: Oct 22 (Mon)

Sex & the Brain: ARTICLE REVIEW DUE

Roselli, C. E., Larkin, K., Resko, J. A., Stellflug, J. N., & Stormshak, F. (2004). The volume of a sexually dimorphic nucleus in the ovine medial preoptic area/anterior hypothalamus varies with sexual partner preference. Endocrinology, 145, 478483. http://tiny.cc/r7vujw Oct 24 (Wed)

Pain I [Guest Lecture: Dr. Bart Manning, Pfizer Inc.]

Oct 26 (Fri)

Pain II

Oct 29 (Mon)

Test #3

7 SECTION #4: COGNITIVE & AFFECTIVE NEUROSCIENCE Week #8: Cognitive/Affective Neuroscience Oct 31 (Wed)

Physiological Substrates of Memory

Nov 2 (Fri)


Squire, L. R. (2009). The legacy of Patient H. M. for neuroscience. Neuron, 61, 6-9. , http://tiny.cc/w8vujw Week #9: Cognitive/Affective Neuroscience Nov 5 (Mon)


Nov 7 (Wed)

Physiological Substrates of Emotion

De Quervain, D. J-F., Kolassa, I-T., Ertl, V., Onyut, P. L., Neuner, F., Elbert. T., & Papassotiropoulos, A. (2007). A deletion variant of α2B-adrenoceptor is related to emotional memory in Europeans and Africans. Nature Neuroscience. , http://tiny.cc/w8vujw Nov 9 (Fri)

Neurogenesis I

Week #10: Neurogenesis & Early Life Stress Nov 14 (Mon) Neurogenesis II Nov 16 (Wed)

Neurogenesis III

Erickson, K. I. et al. (2011). Exercise training increases size of hippocampus and improves memory. Proceedings of the National Academy of Sciences, 1073 1-6. , http://tiny.cc/w8vujw Son, H., Banasr, M., Choi, M., Chae, S. Y., Licznerski, P., Lee, B…..& Duman, R. S. (2012). Neuritin produces antidepressant actions and blocks the neuronal and behavioral deficits caused by chronic stress. Proceedings of the National Academy of Sciences, 109, 11378=11383. http://tiny.cc/d8vujw Nov 18 (Fri) Effects of Stress During Critical Periods Entringer, S., Buss, C., Kumsta, R., Hellhammer, D. H., Wadhwa, P. D., & Wust, S. (2009). Prenatal psychosocial stress exposure is associated with subsequent working memory performance in young women. Behavioral Neuroscience, 123, 886-893. http://tiny.cc/d8vujw

8 Evans, G. W., & Schamberg, M. A. (2009). Childhood poverty, chronic stress, and adult working memory. Proceedings of the National Academy of Sciences, 106, 65456549. http://tiny.cc/c4vujw Week #11: Monday (Nov. 19th) 8:30 to 11 a.m.

TEST #4: Non-cumulative FINAL