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Techniques in. Shoulder & Elbow Surgery 2008;9(3):168-173. 4. O'Toole RV, Riche K, Cannada LK, Hennessy M, Sciadini MF, Shi LL, Woodford M, Harris. MB .
Lewis L. Shi, M.D. Assistant Professor of Orthopaedic Surgery University of Chicago Medical Center Department of Orthopaedic Surgery and Rehabilitation Medicine 5841 S. Maryland Avenue, MC 3079 Chicago, IL 60637 Office: (773) 795-3583 Fax: (773) 702-4384 Email: [email protected] ACADEMIC TRAINING Sept 1996 to June 2000 Sept 2000 to June 2006 June 2006 to June 2011 Aug 2011 to July 2012

EMPLOYMENT Aug 2011 to July 2012 Aug 2011 to July 2012 Sept 2012 to present

B.A., Biochemical Sciences. Harvard College. Cambridge, MA M.D., Harvard Medical School. Boston, MA Residency, Harvard Combined Orthopaedic Residency Program, Massachusetts General Hospital. Boston, MA Fellowship, Harvard Shoulder and Elbow Fellowship, Boston, MA. Mentors: Dr. Jon JP Warner and Dr. Laurence D. Higgins

Assistant in orthopaedics, Massachusetts General Hospital, Boston, MA Assistant in orthopaedics, Brigham and Women’s Hospital, Boston, MA Assistant Professor of Orthopaedic Surgery, University of Chicago Medical Center, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago. Chicago, IL

BOARD CERTIFICATION 2011 American Board of Orthopaedic Surgery. Passed Step 1 ABOS exam. Board-eligible SCHOLARSHIP (a) Peer-reviewed publications in the primary literature, exclusive of abstracts: 1. Shi LL, Zurakowski D, Jones DG, Koris MJ, Thornhill T. Semiconstrained primary and revision total elbow arthroplasty with use of the Coonrad-Morrey prosthesis. J Bone Joint Surg Am. 2007;89(7):1467-75. 2. Thomas KA, Toth JM, Crawford NR, Seim HB 3rd, Shi LL, Harris MB, Turner AS. Bioresorbable polylactide interbody implants in an ovine anterior cervical discectomy and fusion model: three-year results. Spine. 2008;33(7):734-42. 3. Shi LL, Jawa A, Jupiter JB. Vascularized bone graft in humeral defects. Techniques in Shoulder & Elbow Surgery 2008;9(3):168-173. 4. O’Toole RV, Riche K, Cannada LK, Hennessy M, Sciadini MF, Shi LL, Woodford M, Harris MB. Analysis of postoperative knee sepsis after retrograde nail insertion of open femoral shaft fractures. Journal of Orthopaedic Trauma. 2010;24(11):677-82 5. Jawa A, Shi LL, O’Brien T, Wells J, Macy J, Higgins LD, Warner JJP. Prosthesis with Antibiotic-loaded Acrylic Cement (PROSTALAC) Use in Shoulder Arthroplasty Infection. Journal of Bone and Joint Surgery-American. 2011;93-A(21):2001-9. 6. Shi LL, Bae DS, Kocher MS, Micheli LJ, Waters PM. Contained versus uncontained lesions in juvenile elbow osteochondritis dissecans. Journal of Pediatric Orthopaedics. 2012 Apr;32(3)221-5.

7. Freehill MT, Shi LL, Tompson JD, Warner JJP. Suprascapular Neuropathy: Diagnosis and Management. The Physician and Sports medicine. 2012 Feb; 40(1):72-83. 8. Shi LL, Freehill MT, Yannopoulos P, Warner JJP. Suprascapular nerve: is it important in cuff pathology? Advances in Orthopedics. 2012:516985. Epub 2012 Nov 1. 9. Lafosse L, Van Isacker T, Wilson JB, Shi LL. A concise and comprehensive description of shoulder pathology and procedures – the 4D code system. Advances in Orthopedics. 2012:930543 Epub 2012 Dec 4. 10. Shi LL, Edward TB. The role of acromioplasty for management of rotator cuff problems: Where is the evidence? Advances in Orthopedics. 2012:467571. Epub 2012 Dec 19. 11. Lamplot JD, Qin J, Nan G, Wang J, Liu X, Yin L, Tomal J, Li R, Shui W, Zhang H, Kim SH, Zhang W, Zhang J, Kong Y, Denduluri S, Rogers MR, Pratt A, Haydon RC, Luu HH, Angeles JA, Shi LL, He TC. BMP9 Signaling in Stem Cell Differentiation and Osteogenesis. American Journal of Stem Cells. 2013 Mar 8;2(1):1-21. 12. Shui W, Yin L, Luo J, Li R, Zhang W, Zhang J, Huang W, Hu N, Liang X, Deng Z-L, Hu Z, Shi LL, Luu HH, Haydon RC, He T-C, Ho S. 2013. Characterization of chondrocyte scaffold carriers for cell-based gene therapy in articular cartilage repair. J Biomed Mater Res Part A. 2013 Apr 29. doi: 10.1002/jbm.a.34661. 13. Lian Z, Chai W, Shi LL, Chen C, Liu J, Wang Y. Analysis of PPARGC1B, RUNX3 and TBKBP1 polymorphisms in Chinese Han patients with ankylosing spondylitis: a case-control study. PLoS One. 2013 Apr 18;8(4):e61527. 14. Chai W, Lian Z, Chen C, Liu J, Shi LL, Wang Y. JMY Polymorphism Is Related to Severity of Ankylosing Spondylitis in Chinese Han Patients. Genet Test Mol Biomarkers. 2013 Jun 12 Epub. 15. Liu X, Qin J, Luo Q, Bi Y, Zhu G, Jiang W, Kim SH, Li M, Su Y, Nan G, Cui J, Zhang W, Li R, Chen X, Kong Y, Zhang J, Wang J, Rogers MR, Zhang H, Shui W, Zhao C, Wang N, Liang X, Wu N, He Y, Luu HH, Haydon RC, Shi LL, Li T, He TC, Li M. Crosstalk between EGF and BMP9 signaling pathways regulates the osteogenic differentiation of mesenchymal stem cells. Journal of Cellular and Molecular Medicine. J Cell Mol Med. 2013 Jul 11. doi: 10.1111/jcmm.12097. 16. Wang Y, Hong S, Li M, Zhang J, Bi Y, He Y, Liu X, Nan G, Su Y, Zhu G, Li R, Zhang W, Wang J, Zhang H, Kong Y, Shui W, Wu N, He Y, Chen X, Luu HH, Haydon RC, Shi LL, He TC and Qin J. Noggin Resistance Contributes to the Potent Osteogenic Capability of BMP9 in Mesenchymal Stem Cells. Journal of Orthopaedic Research. 2013 Jul 16. doi: 10.1002/jor.22427 17. Sheehan SE, Gaviola GC, Sacks, AC, Gordon RW, Shi LL, Smith SE. Traumatic Shoulder Injuries: A Force Mechanism Analysis, Part 1 - glenohumeral dislocation and instability. American Journal of Radiology. 2013 Aug;201(2):378-93. doi: 10.2214/AJR.12.9986 18. Sheehan SE, Gaviola GC, Sacks, AC, Gordon RW, Shi LL, Smith SE. Traumatic Shoulder Injuries: A Force Mechanism Analysis, Part 2 - complex injuries of the shoulder girdle and proximal humerus. American Journal of Radiology. Accepted and in press. 2013 19. Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, Zhang H, Li R, Kong Y, Chen X, Shui W, Wang N, Zhao C, Wu N, He Y, Nan G, Chen X, Wen S, Zhang H, Deng F, Wan L, Luu HH, Haydon RC, Shi LL, He TC* and Shi Q*. Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9regulated osteogenic differentiation of mesenchymal stem cells. PLOS One. 2013. In press. 20. Shi LL, Boykin RE, Lin A, Warner JJP. Association of suprascapular neuropathy with rotator cuff tendon tears and fatty degeneration. Journal of Shoulder and Elbow Surgery. 2013. Accepted and In press. (b) Non-peer-reviewed original articles

1. Shi LL, Jawa A, Jupiter JB. Long term bone changes in vascularized fibula grafts. The Orthopaedic Journal at Harvard Medical School. Oct. 2008. 2. Srikumaran U, Shi, LL, Higgins LD, Warner JJP. Arthroscopic and open decompression of the suprascapular nerve. Surgical Techniques of the Shoulder, Elbow, and Knee in Sports Medicine. 2nd edition. In press 2012. 3. Shi LL, von Keudell AG, Higgins LD. Treatment of shoulder infections; post arthroscopy, open surgery and arthroplasty. Current Orthopaedic Practice. In press 2012. (c) Book chapters 1. Harris MB, Shi LL, Vacarro AR, Zdeblick TA, Sasso RC. Nonoperative treatment of thoracolumbar spine fractures. Instructional Course Lectures. 58th ed. 629-638. 2009. 2. Shi LL, Wright RJ. The Knee. In Hocherberg MC et al (Eds), Rheumatology 5th edition (Chapter 74, pp. 729-747). Philadelphia, PA: Mosby Elsevier. 2011. 3. Ek ETH, Shi LL, Warner JJP. Disorders of the proximal biceps tendon: Evaluation and treatment. Biceps tenotomy vs. tenodesis. AAOS – The monograph series. In press 2012. (d) Posters and presentations 1. Shi LL, Jones DG, Koris M, Thornhill TS. Results of semi-constrained primary and revision total elbow arthroplasty. Journal of Shoulder and Elbow Surgery. Abstract. 2007:16(20):e27. 2. Wolf BT, Martin SD, Reichmann WM, Shi LL, Thornhill TS. Reinfection of infected total knee arthroplasty after two stage reimplantation: risk factors, treatment, morbidity and final outcome. Poster presentation. American Academy of Orthopaedic Surgeons annual meeting. San Francisco, CA. March 2008. 3. O’Toole RV, Riche K, Cannada LK, Hennessy M, Sciadini MF, Shi LL, Woodford M, Harris MB. Is it Safe to Treat Open Femur Fractures with Retrograde Nails? An Analysis of Postoperative Septic Arthritis. OTA Annual Meeting. Podium presentation. Denver, Colorado. Oct 2008. 4. Shi LL, Konopka JF, Wen G, Wang Q, Chai Y, Jupiter JB. A Comparison of the Outcome of Vascularized Fibular Grafts for the Reconstruction of Large Segmental Defects of the Humerus and Femur. New England Hand Society Annual Meeting. Podium presentation. Sturbridge, MA. Dec 5, 2009 5. Shi LL, Konopka JF, Wen G, Wang Q, Chai Y, Jupiter JB. Vascularized Fibular Grafts Hypertrophy. American Society for Reconstructive Microsurgery 2010 Annual Meeting. Podium presentation. Boca Raton, Florida. Jan 9-12, 2010. 6. Shi LL, Bae DS, Waters PM, Kocher MS, Micheli LJ. Contained versus uncontained lesions in juvenile elbow osteochondritis dissecans. The American Orthopaedics Society for Sports Medicine 2010 Annual Meeting. Podium presentation. Providence, Rhode Island. July 15-18, 2010. 7. Jawa A, Shi LL, O’Brien T, Wells J, Higgins LD, Macy J, Warner JJP. Two-stage reimplantation for shoulder arthroplasty infections. 11th International Congress on Shoulder and Elbow Surgery. E-poster. Edinburgh, UK. Sept. 5-8, 2010. 8. Shi LL, Jupiter JB. Bony Hypertrophy in Vascularized Fibula Grafts. 2010 Challenges in Fracture Care Across Disciplines. Sponsored by AO North America. Podium presentation. Phoenix, AZ. November 11-14, 2010. 9. Shi LL, Boykin RE, Warner JJP. The association of suprascapular neuropathy with rotator cuff tendon tear and fatty degeneration. Podium presentation. American Academy of Orthopaedic Surgeons Annual meeting. San Francisco, CA. February 7, 2012. 10. Sheehan S, Sood S, Brown P, Shi LL, Gaviola G. Traumatic shoulder injuries: a force mechanism analysis. Educational Electronic Exhibit. American Roentgen Ray Society Annual Meeting. Vancouver, 2012. Winner of Gold Medal.

11. Shi LL, Freehill MT, Tompson JD, Warner JJP. Fluoroscopic-guided suprascapular notch injection as a diagnostic tool for suprascapular neuropathy. Poster. European Society for Surgery of Shoulder and Elbow annual meeting. Dubronik, Croatia. Sept 2012. 12. Lafosse L, Van Isacker T, Wilson JB, Shi LL. A concise and comprehensive description of shoulder pathology and procedures – the 4D code system. Poster. European Society for Surgery of Shoulder and Elbow annual meeting. Dubronik, Croatia. Sept 2012. 13. Shi LL, Boykin RE, Warner JJP. The association of suprascapular neuropathy with rotator cuff tendon tear and fatty degeneration. Poster. European Society for Surgery of Shoulder and Elbow annual meeting. Dubronik, Croatia. Sept 2012. 14. Ek ET, Shi LL, Warner JJP. Surgical Treatment of Isolated Type II SLAP Lesions: Repair versus Biceps Tenodesis. Podium presentation. Chinese Orthopaedic Association Annual Meeting. Beijing, China. November 2012. 15. Ek ET, Shi LL, Warner JJP. Surgical Treatment of Isolated Type II SLAP Lesions: Repair versus Biceps Tenodesis. Podium presentation. American Academy of Orthopaedic Surgeons Annual meeting. Chicago, IL. March 2013. 16. Ek ET, Shi LL, Tompson JD, Warner JJP. Reverse Shoulder Arthroplasty With Latissimus Dorsi/Teres Major Transfer: Technique, Rehabilitation And Results. Scientific Exhibit. American Academy of Orthopaedic Surgeons Annual meeting. Chicago, IL. March 2013. 17. Shi LL, Freehill MT, Ek ET, Tompson JD, Higgins LD, Warner JJP. Suprascapular notch injection as a predictor for suprascapular nerve decompression. Poster. American Academy of Orthopaedic Surgeons Annual meeting. Chicago, IL. March 2013. 18. Shi LL, Ek ET, Freehill MT, Vezeridis PS, Tompson JD, Higgins LD, Warner JJP. Suprascapular Neuropathy: An Elusive Cause of Shoulder Pain. Scientific Exhibit. American Academy of Orthopaedic Surgeons Annual meeting. Chicago, IL. March 2013. 19. Shi LL, Freehill MT, Ek ET, Tompson JD, Higgins LD, Warner JJP. Suprascapular notch injection as a predictor for suprascapular nerve decompression. E-Poster. Association of Shoulder and Elbow Surgeon Open meeting. Chicago, IL. March 2013. 20. Shi LL, Ek ET, Freehill MT, Tompson JD, Higgins LD, Warner JJP. Reverse shoulder arthroplasty with latissimus dorsi and teres major transfer: a solution for superior and posterior cuff dysfunction. 12th International Congress of Shoulder and Elbow Surgery. E-poster. Nagoya, Japan. April 2013. 21. Shi LL, Freehill MT, Ek ET, Tompson JD, Higgins LD, Warner JJP. Suprascapular notch injection as a predictor for outcome of suprascapular nerve decompression. 12th International Congress of Shoulder and Elbow Surgery. Podium presentation. Nagoya, Japan. April 2013. 22. Ek ET, Shi LL, Warner JJP. Surgical Treatment of Isolated Type II SLAP Lesions: Repair versus Biceps Tenodesis. E-poster. AANA Annual Meeting. San Antonio, TX. April 2013. 23. Jiang J, Toor A, Shi LL, Koh JL. An Analysis of Perioperative Outcomes in Patients Following Total Shoulder Arthroplasty and Reverse Total Shoulder Arthroplasty. ASES Closed meeting. October 13, 2013. Las Vegas, NV. 24. Toor A, Jiang J, Shi LL, Koh JL. A Comparison Of Perioperative Outcomes Following Total Elbow Arthroplasty In Patients With And Without Diabetes. ASES Open Meeting. AAOS Specialty Day March 15, 2014. New Orleans, LA. (e) Multimedia videos 1. Shi LL, Ek ET, Freehill MT, Vezeridis PS, Tompson JD, Higgins LD, Warner JJP. Suprascapular neuropathy and ossified transverse scapular ligament: Arthroscopic release techniques. Video, VUMEDI.com. June 2012. 2. Ek ET, Tompson JD, Shi LL, Higgin LD, Warner JJ.. Reverse Total Shoulder Arthroplasty with Latissimus Dorsi and Teres Major Transfer. Video, VUMEDI.com. June 2012.

3. Ek ET, Tompson JD, Shi LL, Phillips K, Beal J, Higgins LD, Warner JJ. Rehabilitation following Latissimus Dorsi Tendon Transfer: Use of Biofeedback training. Video, VUMEDI.com. June 2012. HONORS, PRIZES, AND AWARDS 1999 Phi Beta Kappa. Harvard College 1999, 2000 Derek Bok Award for Distinguished Teaching 2000 Magna Cum Laude with Highest Honors, Harvard College 2001 Paul Dudley White Fellowship for International Research, Harvard Medical School 2001 Community Service Award, Harvard Medical School 2009 AAOS Clinical Scientist Development Program (CSDP) participant 2012 Gold Medal presentation. American Roentgen Ray Society Annual Meeting. EDUCATION Harvard College 1997-2000 Teaching fellow, Statistics 100 “Introduction to Statistics” 2000 Guest lecturer, Statistics 100 “Introduction to Statistics” 1999 Teaching fellow, Engineering Sciences 145 “Physiological System Analysis” 2000 Guest lecturer, Engineering Sciences 145 “Physiological System Analysis” SERVICE Harvard College 1999-2000 Co-founder of National Collegiate Table Tennis Association (NCTTA) 2000-2001 Program director, Hepatitis B Education and Prevention Boston Initiative (HEPBI) 2000-2002.1 Clinic organizer, Harvard Square Homeless Clinic 2000-2012 Premedical advisor, Harvard College Harvard Medical School 2009-2012 Member of Faculty Committee on Community Service, Harvard Medical School