population based data from 10 022 cases - Europe PMC

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Feb 6, 1988 - GEORGE BLACKLEDGE, MD, PHD,director. Birmingham and West Midlands Regional Cancer Registry. SUSAN WILSON, BA, statistician.
386

PAPERS

BRITISH MEDICAL JOURNAL

AND

SHORT

VOLUME

296

6 FEBRUARY 1988

REPORTS

Young age as a prognostic factor in cervical population based data from 10 022 cases

cancer:

analysis of

CLIVE A MEANWELL, KRYSTYNA A KELLY, SUSAN WILSON, CLAUDIA ROGINSKI, CIARAN WOODMAN, ROD GRIFFITHS, GEORGE BLACKLEDGE

Abstract The effect of young age on survival in cervical cancer is not fuily known, although evidence has suggested that it is a poor prognostic factor and that young patients should therefore be treated differently from older patients. All 10 022 cases of invasive cervical cancer in the west Midlands during 1957-81, which comprised 10% of the cases in England and Wales, were analysed to determine the prognostic effect of age. Univariate analysis showed a median survival time of 54 months for all cases, with survival rates at five years of 69% for patients aged under 40 and 45% for those aged 40 or older (XI' (log rank)=331-4; p