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Review Article CODEN: IJPRNK IMPACT FACTOR: 4.278 V Krishna Murthy Naik, IJPRBS, 2014; Volume 3(6): 392-401

ISSN: 2277-8713 IJPRBS

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND BIO-SCIENCE A REVIEW ON ITS ETHANOBOTANY, PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF CARDIOSPERMUM HELICACABUM LINN V. KRISHNA MURTHY NAIK1, K. SUDHAKAR BABU1, J. LATHA2, V. PRABHAKAR1 1. Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P, INDIA 2. Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K.University, Anantapuramu, A.P, INDIA

Accepted Date: 14/12/2014; Published Date: 27/12/2014

Abstract: The use of plant as medicine is as old human civilization. Exploration of this traditional knowledge cures to common disease is an attractive prospect. This weed has been known to possess analgesic, antipyretic, antibacterial, anticancer, antioxidant, antifertility and wound healing activity. Cardiospermum halicacabum Linn. Commonly known as “Balloon vine” has many associated utilities, including a remedy for joint pain, the crude extracts from leaf and steam of Cardiospermum halicacabum Linn, phytochemical compounds including oleic acid, arachidic acid, linoleic acid, plamitic acid, stearic acid, oleic acid, eicosenoic acid, have been isolated from this plant. The aim of this review article was to summarize the information to botany, phytochemistry, traditional and pharmacological activity of the Cardiospermum halicacabum Linn. The Plant stem also used antioxidant, analgesic and anti inflammatory and anti diabetic activities are yet to be commercially formulated as modern medicines, even though they have been acclaimed for their therapeutic properties in the traditional systems of medicine. Keywords: Anticancer, Phytochemistry, Medicine, Disease.

Corresponding Author: MR. V. KRISHNA MURTHY NAIK Access Online On: www.ijprbs.com PAPER-QR CODE

How to Cite This Article: V Krishna Murthy Naik, IJPRBS, 2014; Volume 3(6): 392-401

Available Online at www.ijprbs.com

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Review Article CODEN: IJPRNK IMPACT FACTOR: 4.278 V Krishna Murthy Naik, IJPRBS, 2014; Volume 3(6): 392-401

ISSN: 2277-8713 IJPRBS

INTRODUCTION ETHNOBIOLOGICAL TAXONOMY OF BALLOON VINE BY THE IRULAS OF TAMIL NADU: The traditional Irula classification of Balloon vine is complex and has been largely influenced by urbanization. Many aboriginal communities in India, such as the Irulas are still considered in the pre-agricultural stage of development. Traditionally, the Irulas are mainly gatherers and depend on the forest produce for food, medicine and utilities. Their villages are widely dispersed geographically in the reserve forest and foothills. However, some villages are on the adjacent rangelands and consequently are influenced by the large urban centers of modern society. The aboriginal farmers in these rangelands grow herbs and produce (e.g., millets) as a commodity for sale in urban villages of mainstream society. Ragupathy (1992) during his ethno botanical survey of the Irulas in the Thanjavur district of Tamil Nadu recorded the food and medicinal use of several ethnotaxa of Cardiospermum halicacabum. In these surveys, all of the informants were familiar with balloon vine as a food and many (85%) could identify different ethnotaxa used for various utilities. The stem and leaves of this plant are regularly used to make soup and curry. The seeds of some ethnotaxa are used as oral pain relievers or applied to aching joints as a paste. These reports suggest that the Irulas’ classify several ethnotaxa of balloon vine and that these may be respectively associated with a specific utility. Surveys from non-traditional communities indicate that some people (20%) are still familiar with some of the basic traditional knowledge concerning the utility of balloon vine. Surprisingly, it was also noted that many (75%) people in modern urban centers use of balloon vine to treat rheumatoid arthritis, but few (