SC26196 concentration EC (C o n c e n tra tio n M ) SC26196 ... - PLOS

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Figure S2. Δ6 and Δ5 desaturase activities are not involved in ACh-mediated vaso-relaxation. Values are mean ± SD (n = 6). (A) ACh +/- SC26196 in aortae; (B) ...

0.10 0.08 0.06 0.04 0.02 0.00

B EC50 (Concentration M -6)

EC50 (Concentration M -6)

A

0

10-8 M 10-6M 10-4 M

SC26196 concentration

0.05 0.04 0.03 0.02 0.01 0.00

0

10-8 M 10-6 M 10-4 M

SC26196 concentration

Figure S2. Δ6 and Δ5 desaturase activities are not involved in ACh-mediated vaso-relaxation. Values are mean ± SD (n = 6). (A) ACh +/- SC26196 in aortae; (B) ACh +/- SC26196 in mesenteric arteries. Statistical comparisons of effect of dose of inhibitor were by 1-Way ANOVA with Dunnett’s post hoc test. Values significantly different from ACh treatment alone are indicated by *P