Serum concentrations of vascular endothelial growth factor in ... - Nature

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Background: The role of vascular endothelial growth fac- tor (VEGF) in the pathogenesis of retinopathy of prematurity. (ROP) has been clearly established.
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Clinical Investigation

Serum concentrations of vascular endothelial growth factor in relation to retinopathy of prematurity Gunnel Hellgren1,2, Chatarina Löfqvist2, Anna-Lena Hård2, Ingrid Hansen-Pupp3, Magnus Gram4, David Ley3, Lois E Smith5 and Ann Hellström2

Background: The role of vascular endothelial growth factor (VEGF) in the pathogenesis of retinopathy of prematurity (ROP) has been clearly established. However, little is known about temporal changes in circulating VEGF concentrations in the preterm infant. The objective was to determine the longitudinal serum concentrations of VEGF in relation to ROP. Methods: This study included 52 infants born at