Special Article - Europe PMC

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statistical concepts as P (probability) value or corre- ... journals misuse statistical methods and consequently .... prevent errors in the medical literature.
Special Article Introduction to Biostatistics An Annotated Bibliography for Medical Researchers SUSAN T. SACKS, PhD, and STANTON A. GLANTZ, PhD, San Francisco

Biostatistical methods have become thoroughly integrated into modern biomedical and clinical research. Nevertheless, every observer who has evaluated articles in medical journals has noted that as many as half the reported results were based on questionable statistical analysis. This situation, combined with the fact that most errors involve relatively simple statistical procedures, points to the need for researchers and practitioners to be able to personally judge the quality of the statistical analyses in what they read. Fortunately, there are several excellent papers and texts available for those interested. Biostatistical concepts and techniques play a central role in the development and evaluation of medical knowledge. Results of clinical trials are summarized in statistical terms and many people believe treatments must produce changes with "P