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Observations
OBSERVATIONS CLINICAL TRIALS
Subjects no more: what happens when trial participants realize they hold the power? OPEN ACCESS
Patients will hold us all accountable in new and necessary ways Paul Wicks vice president of innovation, Timothy Vaughan director of data science, James Heywood cofounder and chairman PatientsLikeMe, Cambridge, MA 02141, USA
The social contract of the randomized controlled trial is imbalanced: patients adhere to arduous protocols, are randomized to placebo, and are blinded to their health status. Although most participants (>90%) would like a lay summary of results,1 only a minority (
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