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Supp Fig1.pptx - PLOS
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Supp Fig1.pptx - PLOS
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NAc/dose effect of CHX. % Ch an g e fro. m b aselin e (= salin e ) sal. CHX12.5. CHX 25. CHX 50. 0. 50. 100. 150. A. C. *. *. NAc. % Ch an g e fro. m b aselin.
F
150
*
100
50
0
X
0
H
50
25 /3 hr
1g
C H X
sa l
C H X+ N A C
D
dS t/C
*
C H X
150 100
dS t/s al
NAc
25 /1 hr
C
C H X
0
sa l
*
N A c/ C H X
50
N A c/ sa l
*
% Change from baseline (=saline )
50
25
150
% Change from baseline (=saline )
C H X
C H X
NAc/dose effect of CHX
% Change from baseline (= Saline)
x7
25 /3 hr
25 /1 hr
C H X1 2. 5
sa l
% Change from baseline (=saline ) 100
dS t/C H X
C H X
C H X
sa l
% Change from baseline (=saline ) 100
dS t/s al x7
x7
E
N A c/ C H X
N A c/ sa lx 7
% Change from baseline (= Saline)
A B
NAc/CHX + N-acteylcysteine (NAC)
150
*
50
0
dorsal striatum
150
100
*
50
0
150
100
50
0
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